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A Powerful New ‘QR Code’ Untangles Math’s Knottiest Knots
With a newly discovered mathematical tool, researchers are hoping to gain unprecedented insight into the structure of complex knots.
UNE launches new Institute of Public and Planetary Health in honor of David Evans Shaw
Rooted in science and inspired by UNE’s mission to improve the health of people, communities, and the natural world, the David Evans Shaw Institute of Public and Planetary Health brings together expertise UNE's broad expertise to address complex, interconnected challenges, from coastal resilience and climate change to aging populations and mental health.
How can scientists visualize cellular life with greater precision? - Salk Institute for Biological Studies
Highlights Salk researchers collaborated with scientists at Albert Einstein College of Medicine to develop a new class of probes for imaging living cells The probes, called visible-spectrum antigen-stabilizable fluorescent nanobodies (VIS-Fbs), generate high-contrast images with minimal disruption to normal cellular activity The technology enables more precise investigation of complex biological processes, including cell signaling, development, and disease progression LA JOLLA—Fluorescent proteins have revolutionized science, enabling researchers to tag and visualize individual molecules in living cells, tissues, and animals. Using these tools, researchers have watched viruses infect cells in real time, observed cellular trash collection, and tracked the signaling that spurs tumor growth.
Scientists stunned as JWST finds ice clouds on a giant alien planet
Scientists have discovered unexpected water-ice clouds on a distant, Jupiter-like exoplanet, challenging current atmospheric models. By directly imaging Epsilon Indi Ab with the James Webb Space Telescope, they found less ammonia than expected—likely hidden by thick, patchy clouds. The finding reveals new layers of complexity in giant planets and shows how much we still have to learn.
Entertainment complex planned for downtown Clearwater
It’s being designed as the “gateway” to a re-imagined Cleveland Street corridor.
Clearwater $50M entertainment project takes shape
A $50M entertainment project in downtown Clearwater will feature a seven-screen multiplex, dining and attractions aimed at boosting activity along Cleveland Street.
Why Business Owners Delay Exit Planning
Most business owners know they should plan their exit—but identity, fear of loss, and complexity quietly make it far harder than it seems.
Including A 20,000-Cap Arena: Live Nation, OVG & Atlético Madrid To Build Entertainment, Sports & Educational Complex In Spanish Capital
Barsento, a joint venture formed by Live Nation, Oak View Group (OVG), and Atlético de Madrid, alongside the Mayor of Madrid, José Luis Martínez-Almeida,
Moss for ProMarket: How the Professionalization of College Sports Changed Who Wins
The new model in the United States of paying college student athletes emerged from a complex settlement in the 2025 House v. NCAA private antitrust class action. The settlement supercharged Division I schools’ incentives to fund high-revenue sports programs because they need to pay for millions of dollars in required revenue-sharing with their student athletes. The prospect […]
Peak brain power comes after 50: here’s why your business can’t afford to ignore that
Science and data prove what we already know: that many of the cognitive capabilities that matter most in today’s complex, fast-moving organizations improve with age.
As upfront negotiations near, buyers chart path through complex sports market
The DOJ's NFL probe highlights how sports rights complexity can be ‘good for pricing, but hard on strategy’ for brands and buyers.
Scientists stunned as bacteria rewire DNA machinery to shape cells
Cyanobacteria—ancient microbes that oxygenated Earth and made complex life possible—are still revealing surprises billions of years later. Scientists have now discovered that a molecular system once used to separate DNA has been repurposed into something entirely different: a structure that shapes the cell itself.
New study reveals how maze-like magnetic patterns form and evolve in materials
Maze magnetic domains in soft magnetic materials strongly influence energy loss in electric motors, particularly at high temperatures. However, existing models struggle to explain their complex, temperature-dependent behavior. To address this gap, researchers developed an entropy-extended Ginzburg-Landau model combined with data-driven analysis to study these structures. The approach reveals how entropy and energy interactions drive magnetization reversal and increasing domain complexity, providing new insights into magnetic energy-loss mechanisms.
Alpena County approves entertainment complex at fairgrounds
ALPENA — The Alpena County Board of Commissioners approved their portion of a contract which would allow an entertainment complex to be built at the Alpena County Fairgrounds. The project is contingent upon the Alpena County Fairgrounds board’s approval of their portion of the contract. Jason Atwell, Blackwater NE head of production and events, and […]
Harrison County sports complex opens after three years
Leaders cut ribbon on new facility featuring courts, walking track and splash pad.
Bank of Hawaiʻi launches new Center for Family Business and Entrepreneurs
Center helps Hawaiʻi business owners plan for succession, unlock opportunity and navigate complexities of business, family and personal wealth.
Complete Guide to Secrets of Strixhaven’s Mystical Archive Bonus Sheet
The plane of Arcavios is the home of the Biblioplex, a huge library that’s said to have all the known spells in the Multiverse. This is what inspired the first Strixhaven Mystical Archive, and for our return to Strixhaven, WotC saw fit to bring it back!
Engineering, game design faculty turn nuclear science into interactive learning experience
At Kennesaw State University, learning about nuclear energy isn’t limited to textbooks and lectures. Researchers are developing a video game that helps users understand how reactors operate through hands-on experience. At the center of the project titled “Simulating the AP1000: An Educational Game to Promote Understanding of Nuclear Energy Safety and Sustainability” is a collaboration between engineering and game design faculty. The initiative focuses on turning complex nuclear concepts into an interactive learning experience.
Roman Space Telescope Science Platform Will Open New Frontiers in Space Science
Preparations for NASA's soon-to-launch Nancy Grace Roman Space Telescope have already introduced historic changes to the field of astronomy. Starting in 2027, Roman will deliver an unprecedented volume of complex survey data that will be impractical to download to individual computers for analysis. Astronomers and engineers at the Space Telescope Science Institute (STScI), working in close collaboration with the mission’s partners at NASA and Caltech/IPAC, have met these new developments head
Review: Three books on the confusing, complex world of American politics
Three authors explore the American political landscape and offer provocative ideas on how to fix it—and if it is worth saving.
Stateside LIVE! to debut $20M renovation at South Philadelphia sports complex in May
It will open on May 29 with events planned all Memorial Day weekend.
Health Taxes and the IMF: Are Support and Reform Aligned?
Health taxes remain one of the clearest opportunities for countries to raise revenue while improving public health, but how these reforms are supported matters as much as whether they are adopted. The current pattern—where reform commitments are concentrated in lower-income countries, while technical support is more visible elsewhere—raises a practical concern: complex excise reforms may be pursued without commensurate design and implementation support. Given the technical demands of these reforms, this gap could affect both their durability and effectiveness.
Safe2Eat in 2026 – Science-backed guidance for all Europeans!
Now in its sixth year, Safe2Eat remains a flagship EU-wide initiative designed to make food safety science accessible and relevant to everyday life. By translating complex scientific knowledge into practical guidance, the campaign helps consumers better understand how food safety works and how it supports their health and wellbeing.Growing reach across Europe and neighbouring countriesSince its launch, Safe2Eat has steadily expanded its geographical scope. From an initial group of 9 participating countries, the campaign reaches 23 countries across Europe and beyond in 2026. This year’s edition...
ETSU renaming sports complex after major partnership
East Tennessee State University’s Campus Recreation Field Complex is getting a new name and a significant investment in student recreation facilities.
New model helps investors and regulators understand complex businesses and see their positive sides
Warren Buffett advised that you should never invest in a business you can't understand. But that hasn't stopped many investors. New research from the McCombs School of Business at The University of Texas ...
Developers to meet with business owners about replacing historic cottages with 324-unit complex
Tennessee-based Bristol Development Group proposes demolition of colorful Fruitville Road village.
WTOV9 Senior Expo scores big with turnout at The Highlands Sports Complex
The 5th WTOV9 Senior Expo proved to be another success on Tuesday.More than 50 vendors welcomed north of 1,000 people at The Highlands Sports Complex.Among many
Personnel note: Ivan Rodriguez-Seda joins Continental Strategy’s Jax office
'He has a proven record of delivering results on complex issues, securing hundreds of millions in funding, and building coalitions internationally.'
Southcoast Health recognizes team for patient discharge support
Marylouise Gamache and the EOHHS Complex Discharge Support Team received the Southcoast Health Hero for Health Award.
REMSA Health leaders 'perplexed' by Sparks push to consider other ambulance options
Top REMSA Health officials are pushing back against Sparks Mayor Ed Lawson's push to consider other emergency medical service options in the region, saying his
Retro Rewind re-creates the glorious drudgery of working a '90s video store
What the nostalgic throwback lacks in complexity it makes up for in repetitive charm.
Asphalt/concrete plant proposed for former Bentley’s entertainment complex
ASHLEY — Ashley Borough Council will hold a public hearing on Tuesday on a proposed rezoning of the property where the former Bentley’s entertainment complex sits to allow for the development of an asphalt/concrete processing plant.
Google shoehorned Rust into Pixel 10 modem to make legacy code safer
Cellular modems are complex black boxes of legacy code, but Google is making them safer with Rust.
'Beatles vs. Stones' Tribute Show Coming to Rome's Capitol Arts Complex
The Beatles vs. Stones—A Musical Showdown is bringing the ultimate British Invasion tribute to the Capitol Arts Complex in Rome.
Opinion: I was recruited to play a sport here, but first, my family had to pay for it
It was a hot summer day in east Long Island. Hundreds of kids and parents from across the country piled into a sports complex consisting of four adjacent turf baseball fields. The gates were manned by a brigade of staff who were commandeering the large crowd. “Are these credentials right?” they asked as they showed...
The essential role of a health plan in Ohio
How health plans in Ohio can simplify care, improve affordability and provide personal support when families face complex health needs.
From Vision to Reality: Sports Complex Initiative Takes Center Stage at April Greenville-Pitt Power Luncheon
A major community initiative is coming into focus this April, and local leaders will have a front-row seat to the conversation. Andrew Schmidt, President &
Demon Slayer: Kimetsu no Yaiba – The Hinokami Chronicles 2 DLC character Shinobu Kocho (Infinity Castle) launches April 17
Demon Slayer: Kimetsu no Yaiba – The Hinokami Chronicles 2 downloadable content character Shinobu Kocho (Infinity Castle) will launch on April 17, publisher Aniplex and developer CyberConnect…
Making light spin with a gold nanorod
Controlling photon spin, or the handedness of light, is useful for storing and transmitting information. However, generating circularly polarized light typically requires complex or chiral structures. Researchers from the Tokyo University of Science show that hitting a gold nanorod slightly off-center with an electron beam causes the light around it to rotate. This method offers a simpler way to control photon spin and could accelerate the development of smaller, more efficient optical and quantum devices.
The Complex Transformations Underlying MC Escher’s Works
Self-similar images are rather common, which are images in which the same image is repeated on a smaller scale somewhere within the image that one is looking at, something which is also referred to…
Ancient Egyptian stone monument depicting a Roman emperor as a pharaoh discovered in Luxor
A stone slab depicting the Roman emperor Tiberius was found during restoration work at the Karnak temple complex in Luxor.
Neandertals may have hunted and eaten outsiders, chilling cannibalism study finds
A cave in Belgium has revealed unsettling evidence that Neandertals selectively cannibalized outsiders, focusing on women and children. The victims weren’t from the local group and appear to have been treated like prey, with bones butchered for meat and marrow. This suggests the behavior wasn’t ritual, but practical—or possibly linked to intergroup conflict. The discovery paints a darker, more complex picture of Neandertal life during their final millennia.
110,000-year-old discovery rewrites human history: Neanderthals and Homo sapiens worked together
The first-ever published research on Tinshemet Cave reveals that Neanderthals and Homo sapiens in the mid-Middle Paleolithic Levant not only coexisted but actively interacted, sharing technology, lifestyles, and burial customs. These interactions fostered cultural exchange, social complexity, and behavioral innovations, such as formal burial practices and the symbolic use of ochre for decoration. The findings suggest that human connections, rather than isolation, were key drivers of technological and cultural advancements, highlighting the Levant as a crucial crossroads in early human history.
'DWTS' alum Hayley Erbert says her heart is 'breaking into a million pieces' after having first baby with Derek Hough
'DWTS' alum Hayley Erbert says her heart is 'breaking into a million pieces' after having her first baby with Derek Hough two years after a life-threatening health scare: 'Motherhood is even more complex and contradicting than I could have ever imagined.'
Tribute show to feature Beatles, Stones
Beatles vs. Stones tribute show will take the stage April 16 at the Capitol Arts Complex in Rome with music from both iconic bands.
“AI polls” are fake polls
A few weeks after Donald Trump’s second presidential win, I took the train up from London (where I was living at the time) to Oxford to attend a conference on polls and forecasts of the 2024 election. Most of the attendees were pollsters or academics, but I also watched presentations from Aaru and Electric Twin, two companies that do what is interchangeably called synthetic sampling, silicon sampling, or synthetic audiences. Stripped of startup jargon, that means they use large language models (LLMs) to simulate responses to public opinion polls by having AI agents take on the role of survey respondents. I had already heard of Aaru thanks to some articles with eye-catching headlines like “No people, no problem: AI chatbots predict elections better than humans” in the months leading up to Election Day. The founders were making some big, some might even say far-fetched claims, such as: “within two years, we will simulate the entire globe — from the way crops are grown in Ukraine to how that impacts production of oil in Iraq, trade through the strait of Malacca, and elections for the mayor of Baltimore.” When Semafor asked Aaru’s cofounders — Cameron Fink and Ned Koh — about my boss, they said “we respect all those who came before us.” Nate (as he so often does) shared his thoughts on Twitter: Fink and Koh were relatively good-natured about this back-and-forth when we spoke at Oxford. They even offered to mail me one of the t-shirts featuring Nate’s quote they apparently had made. I never took them up on the offer, which I now somewhat regret. These synthetic sampling companies fell off my radar for a while, but they do still exist. In fact, Aaru recently received a $1 billion valuation. Is what they’re doing anywhere close to the most important frontier in AI development? Not by a longshot, especially when Anthropic just developed a model so adept at exploiting software vulnerabilities that it’s only being released to 40 companies. Still, silicon sampling is increasingly finding its way into public polling. Axios reported in March that “a majority of people trust their own doctors and nurses” based on findings from Aaru — without mentioning that the “people” in that sentence were actually LLMs. Around the same time, the Public Sentiment Institute “boosted” their online sample of 373 real survey respondents with 114 AI agents.1 (Spoiler alert: even the co-founder of Electric Twin doesn’t think that’s a particularly defensible approach.) Polling companies like Qualtrics and Ipsos are also developing synthetic data panels. So, what should we make of these … “polls”? Let’s get one thing out of the way: whatever they are, they’re not polls in the way that term is usually defined. Subscribe You can’t replace polls with AI On one hand, using LLMs to essentially make up fake survey respondents sort of sounds like the dumbest idea ever, one that will at best imperfectly replicate real polls while introducing all sorts of biases. On the other hand, with LLMs improving at a remarkable, perhaps even alarming rate, maybe that means I’m a dinosaur at the ripe old age of 24 because I still want to rely on polls that talk to actual people. I’m not going to argue that synthetic samples are completely useless. In fact, as I’ll return to later, there is evidence that some techniques can replicate topline survey results quickly and cheaply. But the marketing from certain companies can be slightly optimistic. “No traditional poll will exist by the time the next general election occurs,” said Fink in 2024. We’re just 206 days away from the midterms, and based on the fact that I still have to collect a bunch of polls every day, I’d say he should have run that prediction by a sample of AI agents before the interview.2 To see why synthetic samples can’t replace polls, here’s a quick primer on how they work. The simplest version of these models involves taking a LLM (like ChatGPT or Claude), giving it a demographic profile (e.g., a white, college-educated woman who lives in Utah and makes $70k a year), and then asking it to respond to a survey question. You repeat that process a few thousand times using different demographic profiles and end up with a sample of synthetic survey responses. The actual models used by private companies are more sophisticated than this, usually because they incorporate more hypothesized demographic characteristics for each agent and provide them with extra information. Aaru, for example, feeds agents a diet of news and information they’d be likely to consume, while Electric Twin incorporates their customers’ proprietary data about the audience they’re trying to replicate. The way Ben Warner, the co-founder of Electric Twin, explained it to me was “we have a large amount of data on […] for instance, 5,000 people. Can we make an accurate prediction of how they would respond to another question?” Still, it should be obvious why synthetic samples can’t replace polls. Polling is fundamentally a data collection process. We might use surveys to make predictions by feeding them into election forecasts, but the main purpose of a poll isn’t prediction, it’s gathering new data about what people think and how they feel. Silicon sampling, on the other hand, produces no new data. It’s simply a model: you input LLM training data, demographic prompts, and a bunch of other information, and it spits out a prediction for what a poll would say. We love models here, but models aren’t polls. That difference is an important philosophical sticking point for most pollsters I talk to. “I think politics should stay away from [synthetic sampling], because we’re trying to […] represent the voice of the people,” said Natalie Jackson, a vice president at GQR Insights. Democratic pollster John Hagner told me: “I think I’m just incredibly skeptical of this idea. I don’t think it’s research. At that point, you’re asking the machine to tell you what you already believe.” Hagner has seen some presentations of early synthetic sampling experiments, but so far, “if it’s being used in a campaign, people are keeping it incredibly quiet.”3 But Eli, I hear you saying, aren’t polls themselves increasingly governed by modeling decisions? Indeed they are: pollsters’ choices on which sampling method to use, how to define their likely voter models, and how to weight their samples can and do lead to dramatic differences in the results they publish. Aaru even referenced these limitations in the methodology statement included with that maternal mortality “poll” — although I’m using the term “methodology statement” loosely here, because it doesn’t really explain how the model works at all. We can ignore the (frankly preposterous) implication that synthetic sampling isn’t subject to a separate set of biases. The important point is that there’s still a meaningful difference between using weighting and other statistical techniques on actual polling data and using a model to predict what a poll would say. The latter is far closer to election forecasts or techniques like MRP — potentially useful models, but not a replacement for polls.4 To be fair, other synthetic sampling companies are perfectly happy with the distinction between polls and models. Warner compared polling and synthetic sampling to different tools in a toolbox. “The mistake I think we make is we think that these new tools should either work in exactly the same way or somehow replace these old tools,” he said. “Rather than thinking of it as, okay, so we’ve always had the hammer, we’ve always had the screwdriver, now we’ve got a saw. But don’t use a saw to try [to] do the job of a hammer.” A quick comment from Nate Eli didn’t ask me for a comment — rather rude of him, don’t you think? But since I’m editing this story, I figured I’d add a few quick thoughts rather than putting words in his mouth. Beyond the frequently misleading marketing, what bothers me about the AI “poll” hype is that as AI tools make statistical inference cheaper and/or better (note that these are not synonyms) that actually increases the comparative value of collecting original data. You might be able to train a model to make a reasonable estimate of what some hard-to-reach poll respondent would say — say, a young Black man who voted for Trump. (Such a person checks a number of boxes for a voter who is usually hard to reach in surveys.) Indeed, this is closely related to what models like the Silver Bulletin forecast already do. They essentially smooth out the kinks in noisy survey data by making inferences based on past voting patterns or national polls or surveys of other states. But you don’t actually know what these voters think unless you’re reaching them directly. If there’s a shift in opinion among this subgroup, you’re not going to detect it. So if I were running a campaign, I’d invest more in going the extra mile to find a representative sample of those voters. And then I’d hire some smart quants — or Claude? — to figure out the implications for campaign strategy based on proprietary data that my competitors didn’t have access to. -Nate Silver Are these models any good? If synthetic surveys are just a new type of model, the next obvious question is whether the models are at least accurate. The answer very much depends on who you ask. On one end of the spectrum, you have the maximalist argument that synthetic sampling is more accurate than actual polls. “It’s an incredibly challenging problem to go to someone and say ‘hey, we’re going to be more accurate at predicting human behavior than you, even when you talk to your customers directly’,” Koh recently told CNBC. In his view, synthetic sampling isn’t a saw to polling’s hammer, it’s “magic.” There’s certainly evidence that synthetic samples can replicate certain survey toplines. But if Aaru does have any examples of their approach outperforming the polls, they’re keeping those to themselves.5 Aaru’s 2024 election model, for example, had Kamala Harris leading in Michigan, Nevada, Pennsylvania, and Wisconsin on November 4th. And although they’ve since taken down their forecast page, they gave Harris a 50.5 percent chance of winning the race on November 2nd.6 After the election, Fink told Semafor he was happy enough with those results because they were “within margin of error,” a term that is completely meaningless when applied to a “sample” of AI agents. And of course, Aaru says their models have improved since 2024, so supposedly now they’d be more accurate than the polls? Still, their stronger argument is on cost: “We are significantly faster and cheaper than traditional polling, and still more accurate,” said Fink. The first two claims are undeniably true, but the third brings us to the opposite end of the spectrum. Both Jackson and Hagner are skeptical that these models are reliable for anything beyond replicating common survey toplines. “I just […] don’t think the machines are what we want when we’re looking for nuanced views. My example on this is people in Arizona and Nevada in 2024 who voted for Trump and voted for expanding abortion in their states on ballot initiatives,” said Jackson. Hagner identified another issue. Maybe the synthetic respondents, like sycophantic LLMs, are inhuman in one important way: they’re too nice. “The reports that have come through at the meetings that I’ve been at are that the early experiments on this, they cannot get respondents to be as racist or sexist or, frankly, as negative as human respondents,” he said. Academic research mostly agrees on this point. While there are some papers that show promising results when using LLMs to replicate polling data, most show that LLMs suffer from various quirks like producing too few “don’t know” responses and can seriously overpredict the favorability of politicians like Donald Trump and Kamala Harris. They also seem to struggle with too little variation between demographic subgroups, so the difference in predicted opinion between Democrats and Republicans, for example, is too small. When I asked Warner about these studies, his response to these papers was that just because academics can’t get synthetic sampling to work doesn’t mean that the technique doesn’t work in general. “Actually, the argument is, okay, yours does not [work]. That does not mean […] for this complex set of machinery, which uses a lot of investment, a lot of time, a lot of money, you can’t get it to work.” Cards on the table, I’m somewhat sympathetic to this argument because academics aren’t exactly great at making election forecasts. Usually, the people with skin in the game are the most accurate. Warner’s argument is that the approach Electric Twin takes — which includes, for example, making multiple predictions for each synthetic respondent using different models and prompts and subsequently averaging those to get a final prediction in a sort of ensemble forecast — produces better results than the simpler academic models. Warner shared a comparison between his method and the method from a recent academic paper with me, and Electric Twin was indeed able to get more accurate replication. But even still, he acknowledged that synthetic sampling “is not a crystal ball.” “If you asked me, do I think using other data sources will be more accurate than asking somebody who they will vote for, I would probably say no. But if you asked me ‘would your system be useful for our turnout modeling today?’ I would say yes.” For better or worse, it looks like the method is already getting more popular in the market research world. Most of the clients Aaru touts these days are businesses like EY and McDonald’s. And AI will probably begin to pop up in other parts of the political polling process. Pollsters are already using it to code open-ended survey responses, and some firms, like YouGov, are testing using LLMs to ask survey respondents questions. More worryingly, one danger to actual polls is that AI agents can be used to infiltrate online surveys. Most online polls use various checks to prevent that from happening, but there’s conflicting evidence on how effective those filters are and how prevalent AI agents currently are in online panels. If those agents ever become impossible to detect, it might spell the end of online polling, but the solution isn’t to replace all of your respondents with ChatGPT. Silver Bulletin is a reader-supported publication. To receive new posts and support our work, consider becoming a subscriber. Subscribe 1 That particular poll obviously doesn’t meet Silver Bulletin standards for aggregation. But we exclude all Public Sentiment Institute polls from our averages because we classify them as an amateur polling firm. 2 You could argue that Fink meant the next presidential election, but (a) I’m also confident we’ll still have real polls in 2028 and (b) in that case he should have asked an LLM to define “general election.” 3 Quick caveat: that’s reporting from a Democratic pollster. It’s possible that Republicans are more willing to use AI in political campaigns. 4 Indeed, Silver Bulletin does not include “polls” produced by MRP in our forecasts or averages, and we think it’s extremely misleading when their practitioners describe them in a way that suggests original data had been collected among a large number of states or Congressional districts. 5 A recent report from Aaru and EY did show two examples of a synthetic estimate being closer than a survey to a real-world benchmark — but I’d take those findings with a grain of salt because the report reads more like an ad and didn’t involve any sort of prediction being made ahead of time. 6 For comparison, our odds for Harris on the same day were 48.2 percent.
Pool at Altru Sports Complex will also house UND diving facility to simulate low gravity
The neutral buoyancy facility will be built under the floor of the pool's deep end and used for experiments, research and training in the space studies program.
Ontario’s big play: Building a sports empire in the Inland Empire
The Inland Empire city is experiencing rapid changes — the latest addition being a mega sports complex. Here's what residents and visitors can expect.
Cenkusha Launches C1: An AI-Enabled Business Management System that Reveals How Value Flows in Organizations
Cenkusha is a technology company that provides the organizational nervous system and structural backbone that modern enterprises need to operate intelligently in an increasingly complex world.
Public exhibit blends art, science and community knowledge
An art and science exhibit this spring at the Morris Thompson Cultural and Visitors Center in Fairbanks explores the beauty, complexity and changing nature of Alaska’s winter.
Gadsden to invest $2.7 million in sports complex upgrades along Coosa River
Gadsden city leaders are investing millions of dollars into the city’s sports complex, with new construction aimed at expanding playing space and drawing larger
Scientists say we’ve been treating Alzheimer’s all wrong
Alzheimer’s isn’t just one problem—it’s a tangled mix of biology, aging, and overall health. That’s why drugs targeting a single factor have fallen short, even as new treatments show modest benefits. Scientists are now pushing toward multi-pronged strategies, from gene editing to brain-cell rejuvenation and gut health interventions. The goal: stop treating Alzheimer’s as one disease and start tackling it as a complex system.
Adyen tool speeds business payments
Financial operations at global enterprises remain “stubbornly complex,” as treasury teams juggle multiple banking and payment systems, the company said.
Judge rules youth organization can keep Waukee sports complex
A judge ruled in favor of the Iowa Youth Athletic Foundation, allowing the organization to retain ownership of the Kettlestone Sports Complex in Waukee after a property tax dispute.
Allies or Adversaries? Science Diplomacy’s Calibration in the President’s Budget Request
Nestled in the cuts and investments of interest to the S&T community is a more complex story of how the administration is approaching the practice of science diplomacy.
3L Rachel Sadler Charts Path in Brain Health, Technology, and Policy Through UC Law SF’s Health Law Concentration - UC Law San Francisco (Formerly UC Hastings)
3L Rachel Sadler studies health law and policy at UC Law SF while researching the legal implications of neurotechnology and other emerging tools that may affect human cognition. 3L student Rachel Sadler shares how UC Law SF’s Health Law Concentration prepared her for a career focused on the intersection of brain health, government policy, and technology. Gained a detailed understanding of how U.S. health care is regulated and where policy reform is needed through coursework and research. Interned with state and federal agencies that regulate health care services and worked with a major health care provider’s bioethics department. Plans to pursue a career focused on protecting cognitive liberty and mental privacy as new technologies reshape healthcare. 3L Rachel Sadler: The Health Law Concentration has given me fluency in one of the most complex regulated industries and the tools to become an effective advocate for better health policy. Before coming to law school, I spent a decade teaching and working with teachers and administrators on high school programming for multilingual learners. Healthcare kept emerging as the most powerful driver of student outcomes. I wanted to understand how to make effective policy change in this area and how to use existing law to defend people’s health rights in California. Through the concentration’s coursework, I gained a sophisticated understanding of how U.S. healthcare is regulated. I also learned where the pressure points for reform exist. The courses gave me space to develop what became my central research interest: how law and policy can be built to protect human cognition and healthy brain development, particularly regarding new technologies such as generative AI and neurotechnology. The health law faculty were instrumental in that process, genuinely invested in helping me and other students define and pursue our own intellectual vision. During law school, I interned at the General Counsel’s Office for Region IX of the U.S. Department of Health and Human Services. I also externed at the California Department of Justice’s Health, Education and Welfare Division. Additionally, I externed at Kaiser Permanente Northern California’s Bioethics Department. Alongside those placements, I conducted extensive independent research on mental privacy and emerging neurotechnology, working closely with Professors Emily Murphy and George Horvath. That research became the throughline of my law school experience and the foundation of my current policy focus. I must also credit Nicole Ozer of the Center for Constitutional Democracy (CCD), whose deep knowledge of California privacy law and the public-interest privacy landscape deeply informed my work. I currently serve a research assistant with the CCD, where I spearhead the development of K-12 educational resources in partnership with law faculty and students. I’ve found UC Law SF to be an ideal place for second-career, nontraditional students. There is a tremendous diversity of life and career experience here, and I felt fully welcomed into the community, despite returning as a student at a different stage of life. I came to law school wanting to promote equity in California’s healthcare system. I am leaving with a sharper and more specific ambition: to build a policy career focused on protecting cognitive liberty and mental privacy from technological intrusion. This is both an urgent and underserved area of law, and I want to be part of defining this landscape going forward. Whether as a practicing attorney or a policy advisor, I plan to work on these issues after law school. I strongly recommend UC Law SF and the Health Law Concentration. When I arrived in law school, I worried the concentration would be narrow and that my non-clinical background would be a disadvantage. The opposite was true. The health law faculty thinks about health expansively, encompassing social determinants of health, structural inequity, and emerging technologies alongside the regulatory mechanics of the industry. The faculty are accessible, intellectually generous, and genuinely invested in students’ development. I found my research vision here, and I deeply appreciate the concentration’s role in this. The Evidence of Success series highlights UC Law SF students as they share how the College’s opportunities equip them with the experience, skills, and confidence to excel in the legal profession.
McKinney advances plans for 300-acre sports and entertainment complex
City leaders in McKinney have taken the first step toward developing a new entertainment amenity in the Collin County seat. McKinney City Council on April 7 authorized the city manager to negotiate a...
Experts set 2030 nutrition science goals for resilient food systems
As the second quarter of the 21st century unfolds, experts are examining the state of nutrition as the UN Sustainable Development Goals (SDG) deadline looms with five years remaining. To achieve these targets, a new paper outlines key goals for nutrition science from 2025 to 2030. The Frontiers in Nutrition publication discusses the interconnectedness between nutrition, food security, and sustainability in complex food systems affected by shocks, policies, and environmental limits. The researchers reveal how these modern factors impact nutrition science and shape research agendas.
Kansas City youth sports complex proposal prioritizes local students
The City Council will vote Thursday on a resolution directing the city manager to identify property and financing for the facility.
Poke makes AI agents as easy as sending a text
Poke brings AI agents to everyday users via text message by handling tasks and automations without complex setup, apps, or technical know-how.
Science Communications with Natasha Kassulke
Are you interested in learning how to turn complex ideas into messages people actually understand? Then Science Communication is the perfect class for you! This fall 2026 semester, Science Communication (Hybrid) will be taught by instructor Natasha Kassulke. WHY TAKE THIS COURSE? ● Earn college credit in high school ● Explain ideas clearly and confidentlyStory...
Nashville Yards entertainment complex set for April 29 opening
Hooky space within CAA-anchored building will be highlighted by seven-screen cineplex, bowling, arcade
Nashville Yards entertainment complex sets April 29 opening
Hooky space within CAA-anchored building will be highlighted by seven-screen cineplex, bowling, arcade
How does mitochondrial DNA affect your health? - Salk Institute for Biological Studies
Highlights Salk scientists have created a platform to study mitochondrial DNA mutations that lead or contribute to human disease They generated a library of 155 mitochondrial DNA mutant cells, nearly the human level of mitochondrial DNA mutant diversity The platform and library will accelerate innovation in the mitochondrial disease therapeutic space LA JOLLA—Some of your most important life partners are the mitochondria that power all your cells. You and these little cellular powerhouses are in a 1.5-billion-year-old evolutionary relationship—but mitochondria brought some baggage. Mitochondria brought their own DNA with them when they joined with the bigger, more complex cells so long ago, and today that mitochondrial DNA influences human health.
Scientists say we’ve been wrong about what makes sprinters fast
A new international study is shaking up how we think about elite sprinting, arguing there’s no single “perfect” running style behind the world’s fastest athletes. Instead, speed emerges from a complex mix of an individual’s body, coordination, strength, and training—meaning every top sprinter moves differently. Using examples like rising Australian star Gout Gout, researchers show that unique physical traits can produce world-class speed without copying anyone else’s technique.
$9M 24-acre Jay park renovation will include sports complex, disaster hub
A $9.1 million upgrade of Jay park will include full-scale sports complex, playground, outdoor workout area and a disaster response hub.
Kansas City explores possibility of building urban youth sports complex
Members of a city council committee directed the city manager’s office to study the possibility of developing an urban youth sports facility.
Waukee basketball complex owner wins tax dispute with Dallas County
A Dallas County judge said \
The Boundless Deep: Young Tennyson, Science, and the Crisis of Belief by Richard Holmes
Pantheon Review by Walter Cummins The image of Alfred Tennyson I’ve carried for decades goes back to the childhood card game of Authors that depicts him with a stately continence sharpened by a jutting black beard. He’s formidable, his aura superior. Holmes opens his biography of the youthful Tennyson by describing the similar formality of the imposing Tennyson statue at Trinty College Cambridge, sharing the honor with other Trinity greats, including Isaac Newton, Francis Bacon, and Thomas Babington Macaulay. Holmes doesn’t want to chip away at that statue but rather reveal its inner youthful core of the man—tall, handsome, and talented but unformed, emerging from a disturbed family of addicted or insane male siblings and four unusual sisters struggling under a violent alcoholic clergyman father. Alfred was certainly statuesque, but would he end up a block of unformed stone like his equally promising brothers? He was youngest of three equally regarded Tennyson brothers at Cambridge, all bright, handsome, and talented, in fact Alfred regarded by some as less promising than his elders who also wrote poetry. Yet Alfred wrote one of his major poems, “The Kraken,” at twenty, revealing both his talent, his interest in geological forces, and the haunting creature that embodied his anxieties. While Holmes focuses on Tennyson of the 1830s and 1840s, he can’t tell his story without exploring his involvement with the Victorian intellectual upheaval. Tennyson was fascinated by new scientific perspectives, following the latest findings as soon as books and articles were published. He was especially taken with Charles Lyell’s deep studies of geology and the discovery of fossils and a timeline of the planet’s development that did much to question fundamental religious assumptions. The impact of these discoveries is reflected in Tennyson’s poetry and led to the crisis in belief he shared with so many contemporaries. He was especially taken by the cycles of destruction and renewal that informed the struggles he confronted in In Memoriam, Maud, and Idylls of the King. Tennyson was only one of the eventual major figures at Cambridge at the same time, young men just beginning to realize their potential. Charles Darwin was at Christ College, although there is no evidence that he and Tennyson even met as students or later in life. Yet evolution became significant in Tennyson’s thinking and the issues of his poetry. One of Tennyson’s best and most important Cambridge friends was Edward FitzGerald, who became the translator of The Rubáiyát of Omar Khayyám and in their on and off relationship served as Tennyson’s harshest critic. FitzGerald was also a friend of the novelist William Makepeace Thackeray, the two of them partying in Paris as undergraduates. That connection led to a friendship between Thackeray and Tennyson. Others who came to play significant roles in Tennyson’s life were Thomas Carlyle, the Brownings, and the Pre-Raphaelites. Tennyson’s deepest friend at college was Arthur Hallam, who at twenty wrote a glowing review of Tennyson’s first poetry collection, travelled on European adventures with him, and fell in love with his sister Emily. Hallam was also regarded as one more very promising Cambridge student. His sudden death at twenty-two in Vienna from a stroke while travelling with his father devastated many friends, but perhaps Tennyson most of all. He did not write immediate poems of grief but took years to compile those collected in In Memoriam A.H.H., published in 1850, almost twenty years after Hallam’s death For all of Tennyson’s early poetic successes and successes, Holmes reveals him as an often troubled young man suffering periods of depression, fearing planetary upheaval, concerned about supporting himself, disappointed in romances, and worried that he would inherit the family’s mental illness tendencies. Yet despite his seeming withdrawals, he was always writing poetry that he kept private and would not let go, constantly revising. 1850 became a transformative year for Tennyson. He finally consented to publishing In Memoriam with a last-minute prologue that acknowledged God and perhaps convinced the religious Emily Sellwood to marry him after years of pursuit.. He opened up to Emily, revealing his struggles with fears of depression and “weird seizures.” The devastating event of that time was the stillborn death of his unnamed first son. It shook him, but Emily’s faith brought them closer and convinced him to believe in an afterlife. Two later sons survived. With the death of William Wordworth in April of 1950, Tennyson was named poet laureate at age forty-one, reluctantly accepting. It’s as if Tennyson’s life split in half in that year. He lived another forty years, now a recognized success, with the prestige of being an official poet writing patriotic verse, wealthy and revered, no longer the insecure young man seeking an outlet for his immense talent. He earned a place in the Authors deck, now dignified and in 1884 elevated to the peerage as Arthur, Lord Tennyson. Richard Holmes is the author of twenty previous books on the Romantics and Victorians, several of which received awards. The Boundless Deep was shortlisted for the 2025 Baillie Gifford Prize for Non-Fiction. He captures the complex vicissitudes of Tennyson’s youth, illustrated by frequent excerpts from the poetry, placing that life in the full context of the shattering discoveries that led to an upheaval of thought in the Victorian age.
Affordability and Preventive Public Health Policy
Affordability pressures increasingly shape health risk in the United States, influencing both the upstream conditions that sustain health and the downstream ability to access health promoting resources. Financial stability is a key driver of health, affecting patterns of health, health care use, and the tradeoffs people must make among competing needs. The economic policy landscape aimed at improving financial security for Americans is expansive, complex, and often difficult to organize, making it challenging to discuss how different policies influence financial resilience and population health. We propose the Earn–Keep–Grow framework as a practical way to organize and guide discussion of these policies in population health research and policy decision-making.
Immunic COO highlights the importance of science-led innovation to mark World Health Day
Immunic Inc (NASDAQ:IMUX, FRA:10VA) chief operating officer Jason Tardio talked with Proactive's Stephen Gunnion about the importance of science-led innovation in tackling neurological diseases, particularly multiple sclerosis, on World Health Day 2026. Tardio highlighted that the biotech industry is fundamentally grounded in scientific research and data, noting that “everything we do is rooted in science.” He explained that Immunic is focused on developing innovative therapies designed to improve patient outcomes and address significant unmet medical needs. The discussion centred on multiple sclerosis (MS), a complex neurological disease that continues to present challenges despite decades of progress. Tardio pointed out that while advancements have been made, “the disease is not solved for,” with many patients still experiencing disability progression and requiring safer, more tolerable treatments. He emphasised the urgent need for innovation, particularly in progressive forms of MS where treatment options remain extremely limited. Immunic’s lead asset, vidofludimus calcium, is being developed as a novel approach aimed at addressing the full spectrum of the disease. Tardio also reinforced the broader mission of the healthcare and biotech sectors, stating that the ultimate goal is to help individuals “live a better quality of life” and “a healthier life longer.” Watch the full interview to learn more about Immunic’s approach to advancing MS treatment through science. For more videos like this, visit Proactive's YouTube channel, like this video, subscribe to the channel, and enable notifications so you never miss an update. #Immunic #MultipleSclerosis #BiotechInnovation #Healthcare #MSResearch #DrugDevelopment #ClinicalTrials #Neurology #WorldHealthDay #ScienceDriven #VidofludimusCalcium #PharmaNews #BiotechNews
Bill Ackman’s Fund Offers to Buy Universal Music in $64 Billion Deal
The complex transaction pitched by the billionaire hedge fund manager would need to pass muster with the music label’s shareholders.
Club sports athletes report minimal damage after Morning on the Green festival
Women's Ultimate Frisbee and Rugby Team Captains share their thoughts on the impact of the Morning on The Green Festival on the Lower Sports Complex fields.
Earth’s most powerful ocean current didn’t form the way we thought
A colossal ocean current encircling Antarctica—stronger than all the world’s rivers combined—played a far more complex role in shaping Earth’s climate than scientists once thought. New research shows it didn’t form just because ocean gateways opened, but required shifting continents and powerful winds to align. This shift helped pull carbon dioxide out of the atmosphere, contributing to a major cooling event that transformed Earth into the ice-covered world we know today.
Construction on Rockrose Sports Complex ‘ahead of schedule’
Over six months since the initial groundbreaking of Kids Inc.’s Rockrose Sports Complex, progress continues to be made on the project.
Fire officials release findings from 2025 Millcreek business complex fire
Millcreek Township fire officials have released the findings of a formal After Action Review (AAR) following a massive fire at a business complex in December. The assessment evaluated the departmen…
Stafford Businessman Seeks to Build Massive Sports Complex at Buc-ee’s Site
The Colosseum is looking to build a state-of-the-art 300,000-square-foot sports and recreation complex at the Stafford County Buc-ee's site.
Expanding Digital Horizons: A Practitioner's Guide to the Newly Expanded IRS Business Tax Account — Current Federal Tax Developments
On April 6, 2026, the Internal Revenue Service released News Release IR-2026-46, marking a significant milestone in the agency's ongoing service improvement efforts. For CPAs and EAs navigating the daily complexities of tax administration, the newly expanded Business Tax Account (BTA) platform promi
Lawmakers propose $10M for Barren County sports complex
House Bill 900 allocates the money for the 2027–2028 fiscal year through the Budget Reserve Trust Fund Account.
Scientists found a “lost world” of animals that shouldn’t exist yet
A remarkable fossil discovery in southwest China is rewriting the story of how complex animal life began, showing that many key animal groups appeared millions of years earlier than scientists once believed. Dating back over 540 million years, the fossils reveal a surprisingly diverse and advanced ecosystem from the late Ediacaran period—before the famous Cambrian explosion. Among the finds are early relatives of starfish, worm-like creatures, and even ancestors of animals with backbones, suggesting that the roots of modern life were already taking shape.
No Time to Read, Plenty to Say
In an era where information is increasingly packaged as entertainment and consumed rapidly, the transmission of meaning has become more fragile. Writers, technologists, and institutions alike are realizing that communication is a complex interaction shaped by audience habits, digital tools, and shifting cultural norms. Each alteration not only affects what we know but also how we understand. The result is a growing tension between expression and interpretation. One that challenges our assumptions about knowledge, attention, and responsibility in the modern world.
AI That Forecasts Hurricanes Years Ahead: Inside BU Research
At Boston University, research is the driving force behind innovation that spans industries and shapes the future. BU empowers faculty and students to tackle complex global challenges, producing thousands of publications each year and fueling breakthroughs that extend far beyond campus. Learn more about the innovators whose work powers discoveries on and off campus. Boston […]
Newly discovered fossils give scientists first look at the evolution of early complex animals
Newly discovered fossils have given scientists their first real glimpse of when Earth made a crucial transition from plants and unrecognizably simple animals to the complex creatures that took over the world and would eventually lead to us.
NASA shoehorns in human science on Artemis II moon mission
“The most complex machine we’re flying is the human, and we have to understand the human as a system in order to be successful.”
Major changes delays entertainment complex headed for Texas coast
It'll be worth the wait as the company adds go-karting and mini-golf to its plans.
Fossil site in China reveals bevy of complex creatures lived prior to the Cambrian explosion, including a 'Dune'-like sandworm
A site in southwestern China holds a wide array of strange life-forms that emerged prior to the Cambrian explosion, and it pushes back the origin of complex life by millions of years.
Fossils from China show complex life evolved millions of years earlier than once thought
Newfound fossils from China suggest that complex animals were around millions of years earlier than thought, among them possibly our vertebrate ancestors.
I started using Obsidian as a complete beginner and now I understand why people switch and never go back
It can be as simple, or as complex as you want it to be.
Can AI Be My Health Adviser? I Tested Claude and Perplexity With My Real Medical Records to See
Scientists discover fossils that change what we know about evolution
Scientists have discovered fossils in China that reveal a crucial transition from simple to complex life on Earth
K-Pop Star Mark Lee Exits SM Entertainment, Announces He's Leaving NCT 127 and NCT Dream
K-Pop star Mark Lee has announced he's leaving NCT 127 and NCT Dream following the conclusion of his contract with SM Ente...
Gemma 4 and what makes an open model succeed
Having written a lot of model release blog posts, there’s something much harder about reviewing open models when they drop relative to closed models, especially in 2026. In recent years, there were so few open models, so when Llama 3 was released most people were still doing research on Llama 2 and super happy to get an update. When Qwen 3 was released, the Llama 4 fiasco had just gone down, and a whole research community was emerging to study RL on Qwen 2.5 — it was a no brainer to upgrade. Today, when an open model releases, it’s competing with Qwen 3.5, Kimi K2.5, GLM 5, MiniMax M2.5, GPT-OSS, Arcee Large, Nemotron 3, Olmo 3, and others. The space is populated, but still feels full of hidden opportunity. The potential of open models feels like a dark matter, a potential we know is huge, but few clear recipes and examples for how to unlock it are out there. Agentic AI, OpenClaw, and everything brewing in that space is going to spur mass experimentation in open models to complement the likes of Claude and Codex, not replace them. Especially with open models, the benchmarks at release are an extremely incomplete story. In some ways this is exciting, as new open models have a much higher variance and ability to surprise, but it also points at some structural reasons that make building businesses and great AI experiences around open models harder than the closed alternatives. When a new Claude Opus or GPT drops, spending a few hours with them in my agentic workflows is genuinely a good vibe test. For open models, putting them through this test is a category error. Something else to be said about open models in the era of agents is that they get out of the debate of integration, harnesses, and tools and let us see close to the ground on what exactly is the ability of just a model. Of course, we can’t test some things like search abilities without some tool, but being able to measure exactly the pace of progress of the model alone is a welcome simplification to a systematically opaque AI space. Share The list of factors I’d use to assess a new open-weight model I’m considering investing in includes: Model performance (and size) — how this model performs on benchmarks I care about and how it compares to other models of a similar size. Country of origin — some businesses care deeply about provenance, and if a model was built in China or not. Model license — if a model needs legal approval for use, uptake will be slower at mid-sized and large companies. Tooling at release — many models release with half-broken, or at least substantially slower, implementations in popular software like vLLM, Transformers, SGLANG, etc due to pushing the envelope of architectures or tools. Model fine-tunability — how easy or hard it is to modify the given model to your use-case when you actually try and use it. The core problem is that some of these are immediately available at release, e.g. general performance, license, origin, etc. but others such as tooling take day(s) to week(s) to stabilize, and others are open research questions — with no group systematically monitoring fine-tunability. In the early era of open models, the days of Llama 2 or 3 and Qwen pre v3.5, the architectures were fairly simple and the models tended to work out of the box. Some of this was due to the extremely hard work of the Llama, Qwen, Mistral, etc. developer teams. Some is due to the new models being genuinely harder to work with. When it comes to something like Qwen 3.5 or Nemotron 3, with hybrid models (either gated delta net or mamba layers), the tooling is very rough at release. Things you would expect to “just work” often don’t. I’ve been following this area closely since we released Olmo Hybrid with a similar architecture, and Qwen 3.5 is just starting to work well in the various open-source tools that need to all play nice together for RL research. That’s 1.5 months after the release date! This is just to start really investing more into understanding the behavior of the models. Of course, others started working on these models sooner by investing more engineering resources or relying on partially closed software. The fully open and distributed ecosystem takes a long time to get going on some new models. All of this is lead-in for the most important question for open models — how easy is it to adapt to specific use-cases? This is a different problem for different model sizes. Large MoE open-weight models may be used by entities like Cursor who need complex capabilities in their domain, e.g. Composer 2 trained on Kimi K2.5. Other applications can be built on much smaller models, such as Chroma’s Context-1 model for agentic search, built on GPT-OSS 20B. The question of “which models are fine-tunable” is largely background knowledge known by engineers across the industry. There should be a thriving research area here to support the open ecosystem model. The first step is to understand characteristics of different base and post-trained models to understand what they look like. The second step is to tune pretraining recipes for open models so they’re more flexible. Interconnects AI is a reader-supported publication. Consider becoming a subscriber. Subscribe For The ATOM Project and other Interconnects endeavors, we’ve put in substantial effort to measuring adoption trends in the open ecosystem. Everything takes a long time to unfold after a model is first publicly available — and adaptability is why. What we know for sure now, when Qwen has been going from strength to strength with its releases, is that technical staff across the industry has gotten comfortable working with Qwen models. Countless research methods and datasets were made to work with Qwen. It’ll take patience for any other model family to get to this point — a patience I’m not sure many open model builders have. This takes us to Gemma 4, Google’s latest open models. Gemma 3 was released more than a year ago, in March of 2025, and is a bit underrated. Gemma 4 comes in 4 sizes for now, with a bigger, MoE model of over 100B total parameters rumored but not released yet. The models we have today come in sizes of ~5B dense, 8B dense, 26B total 4B active MoE, and 31B dense. I’m most excited that they’re finally adopting a standard Apache 2.0 open source license. This’ll massively boost adoption. The standard of better licenses for strong open-weight LLMs was set by mostly Chinese open model labs in the last 1-2 years, and now U.S. companies are following suit. I will personally be so happy if the horrible Llama licenses and Gemma terms of service were an ~18-month transient dynamic of the industry being nervous about releasing strong open models. The Gemma 4 scores look very solid, the small models have incredible benchmark scores (especially in general domains like LMArena) and the 31B model rivals the recent Qwen 3.5 27B, which is the leading member of that class. The ~30B size range is an important one, as it’s accessible both to researchers and to enterprises looking to deploy the model in real use-cases. Where the 7B model scale is the default for tinkering and research, a 30B model is the default for seeing if an open model can unlock substantial value in your specific workflow — a good mix of intelligence, low price, tractability for downstream training, etc. This takes us back to the above adoption criteria I mentioned for open models and the bigger question — do I think Gemma 4 will be an overwhelming success? Previous Gemma models have been plagued by tooling issues and poorer performance when being finetuned. Gemma 4’s success is going to be entirely determined by ease of use, to a point where a 5-10% swing on benchmarks wouldn’t matter at all. It’s strong enough, small enough, with the right license, and from the U.S., so many companies are going to slot it in. I’m cautiously optimistic that Gemma 4 is going to work better here. Winds are shifting for open models built in America. We saw GPT-OSS go through a bumpy launch to become an overwhelming success. There’s a collective energy around the likes of Reflection, Arcee, Nemotron, Gemma, Olmo, and peers that show substantial demand for building new stacks around open models. There’s capital to be spent on AI stacks across the economy by those who want more ownership of everything, including the model. After launching The ATOM Project 240 days ago, the conversation is shifting into the next stage. Summer of 2025 was a crisis moment where the U.S. AI scene realized it can’t wait and figure out open models after building AGI. The two markets will capture different areas and proceed in parallel. Now that more companies in the U.S. are releasing strong models, we need to improve the ecosystem so that these models are easy to use, understand, and build value around. It’s the hard work to build another inflection point in these adoption plots I’ve been updating consistently, but that’s the work to be done. Join me in it. More data coming soon! Here’s a sneak peek:
Iterative Health, US Heart & Vascular Partner to Advance Community-Based Cardiovascular Research
April 2, 2026 — Iterative Health and US Heart & Vascular (USHV) have announced a strategic partnership to advance research through community-based innovation in cardiovascular care. "Clinical research is one of the most powerful ways we expand access, improve patient outcomes, and shape the future of cardiovascular care," said Robbie Allen, chief executive officer of US Heart & Vascular. "By partnering with Iterative Health, we are strengthening our ability to bring innovative therapies directly into the communities we serve. This collaboration ensures our physicians and patients have access to leading-edge trials while allowing US Heart & Vascular to remain focused on delivering exceptional, physician-led care." Under the agreement, USHV research sites will join Iterative Health’s global site network, which now spans over 100 sites across three continents. The companies share a commitment to advancing clinical research as a driver of care innovation, and this collaboration represents a major milestone for both organizations, strengthening USHV's leadership in community-based cardiovascular research and expanding Iterative Health's multispecialty focus beyond GI, hepatology, and obesity into cardiology. USHV clinical research sites will gain access to Iterative Health's centralized operational backbone, providing end-to-end support across clinical research operations, services, business development, technology innovation, and corporate functions. The strategic partnership reduces operational complexity and unlocks growth potential for USHV research sites while enabling all USHV physicians to expand access to cutting-edge therapies to the thousands of patients they serve annually. "Innovation in cardiovascular medicine shouldn't be limited to a few academic centers," said Thomas Waggoner, DO, MD, RPVI, FACC, FSCAI, FSVM, RPVI, Structural Cardiologist and Medical Director for Clinical Research at Pima Heart & Vascular, and USHV Physician Champion for Clinical Research. "By expanding community-based research across USHV, we're ensuring more patients have access to clinical trials and breakthrough therapies close to home, where trusted relationships with their physicians already exist." This alliance reinforces Iterative Health's standing as the definitive research partner across specialized therapeutic areas, now spanning GI, hepatology, obesity, and cardiovascular care. Trusted by many of the nation's leading provider organizations and biopharma sponsors, Iterative Health's global site network delivers industry-leading trial performance, accelerating life-changing therapies to market at scale. "Entering cardiology through our strategic partnership with US Heart & Vascular is a defining moment for Iterative Health and reflects the strength of our site-serving model," said Jonathan Ng, founder and CEO of Iterative Health. "Together, we are ensuring that thousands of patients have access to the newest available therapies, and that sponsors have a credible, high-performing partner to accelerate cardiovascular trial success." For more information, visit www.iterative.health and https://usheartandvascular.com/.
Singer Will.I.Am Wants To Fix Inner Cities With A Ridiculously Complex $30,000 Trike With Tron Lightcycle Wheels And An AI 'Brain'
Singer Will.I.Am has designed a car, again. This one is a ridiculously complex $30,000 three-wheeler with an AI employee, to save inner cities
How we came to be: Scientists get first look at the evolution of early complex animals
WASHINGTON (AP) — Newly discovered fossils have given scientists their first real glimpse of when Earth made a crucial transition from plants and unrecognizably simple animals to the complex creatures that took over the world and would eventually lead to us.
How we came to be: Scientists get first look at the evolution of early complex animals
Scientists have discovered fossils in China that reveal a crucial transition from simple to complex life on Earth.