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Why we need to talk more about menopause and its health consequences

More than 1 million women in the U.S. start menopause every year, yet this biological certainty is too often shrouded in secrecy or ignored by many mainstream researchers. Horizons moderator William Brangham explores what we do and don’t know about menopause with Dr. Sharon Malone and Dr. Lauren Streicher.

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May 8 • 7:00 PM EDT • Health • pbs.org
Central MN SBDC receives $5,000 grant from Midwest Business Finance Corporation

The Central Minnesota Small Business Development Center (SBDC), hosted by the Herberger Business School at St. Cloud State University, has been awarded a $5,000 grant from Midwest Business Finance Corporation (MBFC). In 2025 alone, the Central MN SBDC served 392 clients, including 228 who were brand new to the SBDC — all receiving free, high-quality business consulting and technical assistance. From [...]

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May 8 • 1:38 PM EDT • Business • today.stcloudstate.edu
What is ‘Blue Dot Fever’ and how is it affecting Syracuse concerts?

Big names like Post Malone, Meghan Trainor and Pussycat Dolls have canceled tour dates.

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May 7 • 11:59 AM EDT • Entertainment • syracuse.com
How a free city program helped San Antonio entrepreneur land shelf space at retail stores

San Antonio entrepreneurs looking to start or grow a business don’t have to do it alone or spend a dime to get started.

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May 7 • 11:42 AM EDT • Business • ksat.com
The first-ever La Chona Festival is coming to Los Angeles

Six legendary norteño bands are coming together to celebrate the first-ever La Chona Festival in Los Angeles on Saturday, June 27.

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May 7 • 9:00 AM EDT • Entertainment • calonews.com
Republicans alone on filibuster-proof immigration enforcement bill

Democrats score no wins five months after insisting on use of body cameras, judicial warrants and a racial profiling ban

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May 7 • 12:08 AM EDT • Politics • njspotlightnews.org
Solo cruises: What to know before booking a cruise alone

I cruised solo on Royal Caribbean's Wonder of the Seas and thought the activities and excursions made it easy to meet people.

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May 6 • 10:17 AM EDT • Business • businessinsider.com
Giving my 10-year-old more independence has made more confident, too

I was scared to let my kids roam alone or have sleepovers. Now that our oldest is almost 11, I think it's time to give them more independence.

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May 6 • 8:11 AM EDT • Business • businessinsider.com
Opinion | New bill would give Minnesota small businesses $100M after ICE surge

ICE actions have resulted in at least $600 million in lost revenue in Minneapolis-St. Paul alone and an estimated $240 million in wages, business leaders write.

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May 6 • 5:59 AM EDT • Business • startribune.com
Military Vets Finally Have a Launchpad for Their Business Dreams in SA

San Antonio is about to become the first city in the country to offer veterans — and their families — a direct path to owning their own business. District 9 Councilwoman Misty Spears is behind a new Small Business Accelerator Program that connects vets with mentors, funding resources, and even a pitch competition — and it's already gotten the green light from the city. Army veteran Melanie McCoy knows firsthand how lonely and confusing starting a business can be without support. Now she's helping lead the charge with a new non-profit called Supply SA, designed so no vet has to figure it out alone. With 75% of San Antonio's economy powered by small businesses, this program could be a game-changer for the whole city. #VeteranOwned #SmallBusinessSA #SanAntonio #MilitaryEntrepreneur #VetBiz

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May 5 • 11:40 PM EDT • Business • ksat.com
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How community-building fuels small business growth

Relationships help fuel greater growth than tools alone.

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May 5 • 9:45 AM EDT • Business • fastcompany.com
How Metro Detroit nonprofit campaign supports mental health awareness

A local group is spreading a simple yet powerful message: you are not alone.

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May 5 • 9:13 AM EDT • Health • clickondetroit.com
Post Malone to Headline Australia’s Strummingbird Festival in 2026

Post Malone marks his return to Australia three years after a sold-out run at Spilt Milk.

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May 4 • 11:23 PM EDT • Entertainment • yahoo.com
Caleb Downs Is the Cowboys’ Best Pick in Years

Caleb Downs very clearly has “it.” It’s extremely premature to make a claim as bold as “best in a decade” before a draft pick touches the field in training camp, let alone at game speed. However, some people have “it”—an aura people can see on film and in real game time. Every draft has a […] The post Caleb Downs Is the Cowboys’ Best Pick in Years appeared first on The Lead.

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May 4 • 3:52 PM EDT • Sports • sports.yahoo.com
Global Health & WASH: May 2026 Funding Opportunities (14 new opportunities!)

The May update for Global Health & WASH brings new calls that cluster around three distinct shifts: LMIC research leadership moving from funder encouragement into a hard eligibility constraint, pharmaceutical and corporate-linked funders running structurally independent education and use-inspired research portfolios at substantial scale, and AI adoption shifting decisively from speculative tool to operational capability across health and WASH systems alike. In LMIC Research Leadership as Eligibility, Not Encouragement, Wellcome anchors the dominant signal of the month with three separate major calls that all require or strongly center LMIC leadership in their basic eligibility architecture. Wellcome’s ESIC Hubs (£1.5-£1.9M per hub over 3-5 years) explicitly requires an LMIC-based lead applicant, treating Global South leadership as a design constraint rather than a participation goal. Wellcome’s Infectious Disease Clinical Trial Development Award funds transdisciplinary teams whose lead must be a mid-career or established researcher based at an organization in Africa, South Asia, or Southeast Asia. Wellcome’s larger Infectious Disease Clinical Trial Award (£1M-£8M for optimizing licensed interventions) requires the administering organization to be in eligible LMIC regions and at least 50% of applicants based there. Around Wellcome, the same pattern shows up at smaller scale and across funders: CHINNOVA channels $1M into West and Central African research institutions for climate-health work; IBRO’s Neuroscience Training Grants explicitly tier ceilings by region of residence with Africa receiving the highest amount ($5,000); IHME’s GBD Emerging Researcher Award reserves at least one of its two annual awards for an LMIC researcher; Sidaction’s HIV Cure call funds research teams across France, the Netherlands, and eligible African countries with a minimum two-country collaboration requirement. Taken together, these calls signal a meaningful shift in how research equity is being operationalized — not as encouragement language at the bottom of a call, but as a structural feature of who can lead, where the work must be administered, and what proportion of the team must be regionally rooted. In Pharma-Funded Independent Medical Education and Use-Inspired Research, the lineup this month is unusually deep. Pfizer alone runs four parallel calls under independent education and quality improvement frameworks: a Migraine and Women’s Health RFP (200K x 2-year, $500K pool), Migraine IME ($200K, $1M pool), JAK Inhibitor evidence-based education ($100K), and Maternal Vaccination HCP Education in Saudi Arabia ($75K), plus a separate Pediatric Pneumococcal Surveillance research call in Saudi Arabia ($400K per project). Novo Nordisk Foundation runs four parallel calls of its own at substantial scale: Infectious Diseases Catalyst Grants (DKK 60M pool, up to DKK 7M collaborative), Non-Diabetic Endocrinology Collaborative Grants (DKK 53M pool, DKK 5-10M per project), Pioneer Innovator Grant Health (DKK 1.1M), and Distinguished Innovator Grant Health (DKK 6.8M). LEO Foundation deploys DKK 2-4M per project for dermatology research excellence. Pfizer’s framing across calls deliberately separates the funding from product promotion, emphasizing measurable practice-relevant change and structural distance between scientific outputs and commercial activity. Novo Nordisk’s “use-inspired” hard filter pushes researchers toward a credible translation pathway from mechanism to deployable tool. The pattern: industry-aligned funders are running structurally independent portfolios at meaningful $ that fund implementation evidence, not promotion. In AI as Operational Capability, Not Speculation, several calls this month explicitly treat AI adoption as a near-term operational question with real evidence and governance requirements, rather than a speculative trend to be watched. Wellcome’s ESIC Hubs frames AI as “the accelerator” for evidence synthesis, asking hubs to translate technical innovation into adoption-ready workflows that can match real-world policy timelines. UNICEF Venture Fund’s new Climate Tech for Children’s Health call funds for-profit startups deploying AI, machine learning, and blockchain in low-resource environments, with a strict requirement that solutions must already have a working prototype with promising pilot results. The Water Research Foundation has launched two simultaneous AI calls treating reproducibility, cybersecurity guardrails, and human-in-the-loop deployments as core design constraints rather than nice-to-haves: one on GenAI and Agentic AI in water utilities ($200K), one on alternatives to water shutoffs that explicitly screens for implementation economics evidence. Nordic Innovation’s quantum technology call (NOK 4.5M) extends the same logic into life science and healthcare, demanding consortium-stage projects mature enough to test with real users. TEF-Health offers €300K in subsidized testing infrastructure for European healthcare AI and robotics SMEs. The pattern: funders are converting AI pilots into playbooks, requiring transfer evidence and risk controls before AI can move from experimentation to sector-wide operational practice. For LMIC-based researchers in infectious disease or evidence synthesis, the three Wellcome calls together represent the deepest concentration of LMIC-led research capital in recent memory — pair the Infectious Disease Clinical Trial Development Award (£200K, deadline May 19) as a strategic pipeline feeder into the larger Infectious Disease Clinical Trial Award (£1-£8M, deadline June 2), since the development award functions explicitly as a track into the larger trial scheme. For Nordic researchers, the four Novo Nordisk Foundation calls plus LEO Foundation and Nordic Innovation Quantum represent ~$30M in regional research capital this cycle, all with deadlines clustered in May-August. For WASH practitioners, the three Water Research Foundation calls together (each up to $200K) are a cluster worth reading across — one on AI deployment, one on shutoff alternatives, one rewarding applied innovation — and the strongest applicants will articulate how their work bridges utility operations to policy-relevant evidence. For US-based clinical researchers and educators, the four Pfizer calls plus the APF Portfolio’s 80+ programs form an unusually accessible recurring pipeline; APF’s prohibition on indirect costs is a meaningful structural feature for early-career applicants whose institutions might otherwise absorb significant overhead. Snapshot of New Opportunities Total Estimated Funding Pool: $100 Million+ USD The grants are organized into three categories: Open Calls: Current grant and opportunities with a deadline. Grants are listed by closing date. 39 open opportunities- 14 new! Rolling Applications: current grant and opportunities with rolling applications (but it’s still best to submit as early as possible). 14 rolling opportunities- 1 new opportunity! Long term planning: Grants that have closed their current rounds, but are expected to open new windows. 4 long term opportunities! A quick tip for returning readers: if you want to jump straight to the newest additions, use CTRL F to search for “New!” and navigate quickly to the latest funding opportunities This post is for paid subscribers. This helps support the time and effort it takes to curate and organize these opportunities. Subscribe To keep this accessible to everyone who needs it, we’re happy to offer pay what you can rates. You can find more details here. Open Calls: Migraine Competitive Grant Program: Migraine and Women’s Health (Quality Improvement and/or Research RFP), Pfizer.*Closing soon!* Pfizer, in collaboration with the American Headache Society, is seeking independent quality improvement and research projects that close persistent gaps in migraine care for women across the United States. The funding logic centers on measurable, practice-relevant change: proposals should generate actionable evidence, tools, or system improvements that can be shared and used widely, not just within a single site. Priority areas span menstrual migraine and screening in women’s health settings, the role of hormonal fluctuations across the lifespan, sex-specific risk factors, comorbidities and quality-of-life burden, and disparities in outcomes by race, ethnicity, and socioeconomic status. The call is structured as a two-step competitive process with an initial Letter of Intent, with the strongest concepts expected to translate scientific insight into implementable improvements in diagnosis, management, and equity. Geographies: United States. Who can apply: U.S.-based organizations (not individuals), including professional schools, healthcare institutions, professional organizations, and other entities focused on healthcare improvement. Funding amount: Up to USD $200,000 total over 2 years; total pool USD $500,000. Targeted Sectors / SDGs: Health; Focus areas: migraine, women’s health, quality improvement, clinical research, menstrual migraine, health disparities. Deadline: LOI: May 5, 2026; Full proposal (by invitation): August 28, 2026. Learn more and apply here. This RFP rewards “shareable impact”: the most competitive submissions will pair rigorous methods with a clear plan for system uptake and dissemination beyond the originating institution. ReSSARC: Strengthening the Health Sector and Food Security in the Central African Republic (AID 013381/01/0) Call for Proposals, Italian Agency for Development Cooperation (AICS). *Closing soon!* AICS is seeking a limited set of high-capacity humanitarian partners to deliver an integrated package that stabilizes essential health services while reducing acute malnutrition and strengthening food security resilience in priority areas of the Central African Republic. The funder’s logic is explicitly nexus-based: proposals should meet urgent, life-saving needs while reinforcing local systems, coordination mechanisms, and community-level capacity so results persist beyond the emergency window. AICS emphasizes inclusion and protection outcomes, expecting gender-sensitive design and explicit measures for groups facing compounded vulnerability, including women, children under five, internally displaced people, and people with disabilities. The call also signals a localization pathway, encouraging stronger collaboration with national NGOs and balanced partnerships, alongside clear coordination with existing cluster and humanitarian actors to minimize duplication and improve coverage. Geographies: Central African Republic (Bangui, Ombella-Mpoko, Ouham, Ouham-Pende, Lim-Pende, Lobaye). Who can apply: Non-profit organizations registered with AICS, plus eligible non-profits without an office in Italy that have a pre-existing collaboration agreement with an AICS-listed organization. Funding amount: Total pool EUR €1,800,000; max EUR €800,000 (single applicant) or EUR €1,000,000 (ATS). Targeted Sectors / SDGs: Health; Focus areas: malnutrition prevention and treatment, maternal and child health, community health services, food security and resilience, localization partnerships Deadline: May 5, 2026. Learn more and apply here. This call is structured to reward partners who can link frontline service delivery to system durability and localization, not just short-term coverage gains. Contracts for Innovation in drug and alcohol addiction healthcare, Innovate UK. *Closing soon!* Innovate UK, on behalf of the Office for Life Sciences Addiction Healthcare Goals program, is procuring R&D to accelerate innovations that can improve treatment outcomes, strengthen recovery, and reduce harm and deaths linked to drug and alcohol addiction. The competition is positioned as a market-facing readiness push: selected projects are expected to advance solutions toward later-stage validation, generate evidence of user acceptability and UK market fit, and map credible routes through regulatory and certification requirements. Innovate UK signals a preference for innovations that can be field-tested in relevant UK settings and progressed to TRL 6 or 7, with practical plans for commercialization after contract completion. This structure favors applicants that can execute most work in-house, co-develop with service providers and people with lived experience, and translate technical progress into deployable tools for addiction healthcare delivery. Geographies: United Kingdom. Who can apply: Single organizations of any size (including EU, EEA, or international) leading delivery, with most work and key deliverables carried out in the UK; subcontractors for specialist skills only. Funding amount: GBP £200,000–1.5 million per project (inclusive of VAT); Total pool: GBP £20 million (across two strands). Targeted Sectors / SDGs: Health; Focus areas: Mental Health, Health Systems Strengthening, Research & Development, Technology Access. Deadline: May 6, 2026 (11:00am). Learn more and apply here. This call uses procurement to pull near-market addiction innovations toward operational proof and adoption pathways in UK services.

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May 4 • 3:59 AM EDT • Health • impactfunding.substack.com
Baseball Drops Finale to Rhode Island

Kingston, R.I. – (May 3, 2026) – The pitching duo of Evan Maloney and Joe Sabbath combined to allow just one run on four hits, as Rhode Island took the Atlantic 10 baseball series finale from Fordham, 5-1, at Bill Beck Field on Sunday

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May 3 • 11:38 AM EDT • Sports • fordhamsports.com
Unified support is vital to Tallahassee’s small businesses

At the Florida Small Business Development Center at Florida A&M University, our mission is to ensure owners are not navigating this journey alone.

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May 3 • 5:03 AM EDT • Business • tallahassee.com
Ronald Acuña Jr. exits game with apparent left hamstring ailment

Can the injury bug leave this team alone, already?

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May 2 • 8:55 PM EDT • Sports • sports.yahoo.com
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Feeling hot-headed this summer? You’re not alone. Science explains why

India News: Have you ever noticed your mood shifting on days when the heat feels almost unbearable? The smallest things start to feel irritating and even routine .

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May 2 • 5:52 AM EDT • Science • timesofindia.indiatimes.com
Paste Ends The Games Coverage That Gave So Many Writers Their Start

After briefly being a standalone site and then being folded into The AV Club, Paste's games writing seems to be no more

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May 1 • 1:12 PM EDT • Technology • aftermath.site
Thoughts on Theology in Science by Kenneth Francis: Berkeley Vs Solipsism

Even if reality were an illusion only perceived by spirits, then there is still a source of order for that illusion, a core source of reality.

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Apr 30 • 4:10 AM EDT • Science • mindmatters.ai
PayPal's new CEO makes Venmo a standalone business unit as potential buyers circle

PayPal is betting that a new corporate structure can reignite growth at a company that has lost ground to Apple, Google and Stripe in the e-commerce battle.

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Apr 29 • 2:15 PM EDT • Business • cnbc.com
Funding and community for women Veteran founders: the Women Veterans Giving Small Business Award

The Women Veterans Giving Small Business Award ensures that women who have served are not building their businesses alone.

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Apr 29 • 9:30 AM EDT • Business • news.va.gov
How UTC’s Mocs Wellness Initiative is reshaping health on campus

On a weekday afternoon inside the Aquatic and Recreation Center, a group of UTC employees moves through a workout they didn’t design on their own. They’re not guessing at exercises. They’re not following a generic plan. And they’re not doing it alone. Instead, they’re working with a team.

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Apr 29 • 8:09 AM EDT • Health • blog.utc.edu
Empty seats 'a symptom of staggering success'

The sight of empty seats in the Manchester City end at Wembley for Saturday's FA Cup semi-final against Southampton has inevitably triggered the usual cycle of lazy jibes from rival fans. Under Pep Guardiola, a trip to England's showpiece venue has shifted from a once-in-a-generation opportunity to a routine commitment. Since 2011, City have visited the national stadium 33 times, and the weekend's clash against the Saints was Guardiola's 25th Wembley appearance alone, including the Premier League meetings with Tottenham in 2018.

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Apr 29 • 3:38 AM EDT • Sports • sports.yahoo.com
Justin Berfield regrets 'Malcolm in the Middle' revival forced costar Erik Per Sullivan back into the spotlight: 'Leave Erik alone!'

‘Malcolm in the Middle’ star Justin Berfield feels bad that the show's revival turned the spotlight on his former costar Erik Per Sullivan after he left Hollywood.

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Apr 28 • 11:42 PM EDT • Entertainment • ew.com
Astorg buys Thermo Fisher Microbiology business

Astorg has agreed to acquire Thermo Fisher Scientific’s microbiology business, creating a standalone diagnostics platform backed by private equity investment.

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Apr 27 • 10:16 PM EDT • Business • marketsgroup.org
City touts long-term rewards of hosting NFL Draft even as some businesses took losses

Although local businesses had been hoping for better sales during the NFL Draft, officials remain optimistic that the success of the event will bring visitors...

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Apr 27 • 6:19 PM EDT • Business • post-gazette.com
The best, boldest and most 'wait, what?' Stagecoach outfits, from Sydney Sweeney’s corset to Brittany and Patrick Mahomes' coordinated country-chic

From Sydney Sweeney's lingerie saloon moment to Post Malone's quadruple denim ensemble, the best Stagecoach looks went beyond the basics.

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Apr 27 • 2:11 PM EDT • Entertainment • yahoo.com
Prisco's NFL Draft 2026 grades for every team, including best and worst picks for all 32 franchises

The Chiefs stand alone with an A+ in after a dominant draft haul

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Apr 26 • 6:25 PM EDT • Sports • cbssports.com
Stagecoach 2026: How to watch livestream with Post Malone, Hootie & the Blowfish

You can also catch Ludacris, Warren Zeiders and Third Eye Blind on Amazon Music and Prime Video's Sunday Stagecoach livestream, which starts at 3 p.m. Pacific.

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Apr 26 • 6:00 AM EDT • Entertainment • latimes.com
How to use habit-stacking to reach your health and wellness goals

Habit-stacking, a technique that’s gotten a lot of attention in recent years, can create a structured and effective routine when motivation alone isn’t enough.

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Apr 26 • 6:00 AM EDT • Health • washingtonpost.com
Other states made bolder moves to fix mental health care. What lessons does this hold for SC?

South Carolina is hardly alone in struggling to care for the mentally ill inmates filling its jails. But other states have made greater strides in devising potential fixes.

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Apr 26 • 5:00 AM EDT • Health • postandcourier.com
Michigan group pushes to get big money out of politics

A new push to limit corporate money in Michigan politics appears to be gaining traction.There is strong bipartisan support for restricting political contributions from regulated monopolies and companies seeking government contracts, according to a survey commissioned by supporters of the proposal. S...

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Apr 25 • 12:10 AM EDT • Politics • thefulcrum.us
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College basketball rankings: North Carolina tumbles after Henri Veesaar's NBA Draft declaration

New North Carolina coach Michael Malone lost a would-be roster cornerstone when Veesaar decided to make the leap to the next level

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Apr 24 • 3:57 PM EDT • Sports • cbssports.com
UNC big man Henri Veesaar declares for 2026 NBA Draft, leaving massive hole for Michael Malone

UNC big man Henri Veesaar declares for 2026 NBA Draft, what's next for UNC basketball

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Apr 24 • 11:41 AM EDT • Sports • cbssports.com
Apple’s Cal AI crackdown signals it’s still policing the App Store

Apple tells TechCrunch Cal AI was removed not for web payments alone, but for deceptive billing, manipulative tactics, and App Store rule violations.

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Apr 21 • 3:09 PM EDT • Technology • techcrunch.com
Responding to Today's Gaps for Tomorrow's Health Emergencies: 2026 Ready or Not Report

Join Trust for America’s Health (TFAH) for a Congressional Briefing and National Webinar on the latest information on public health emergency readiness and findings from TFAH’s upcoming report, Ready or Not 2026: Protecting the Public’s Health from Diseases, Disasters, and Bioterrorism – releasing May 7th. The past year alone saw the U.S. facing the most […]

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Apr 21 • 2:47 PM EDT • Health • tfah.org
Science Research Students Present at Terra NYC Semifinals

By DORIS CHEN and YUEHAN DAI Nineteen Midwood students showcased months of independent research at the Terra NYC STEM Fair on March 1 at Stuyvesant High School, with 12 groups being part of the semifinals and one group making it to the finals. Seniors Charlotte Maloney and Karen Zevelev

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Apr 21 • 1:46 PM EDT • Science • midwoodargus.com
The World’s Forests Won’t Be Saved by Science Alone: We Need Better Communication

Research tells us that we need sustainable forest practices. But how does this knowledge lead to action?

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Apr 21 • 11:00 AM EDT • Science • therevelator.org
Lancaster Democratic candidates to host public town hall

Democratic legislative candidates Nancy Mannion, James Malone and Chad Gleissl will host a town hall Thursday in Manheim Borough to answer voter questions.

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Apr 20 • 12:36 PM EDT • Politics • lancasteronline.com
2026 Best Business Schools | Total Cost & Scholarships At P&Q’s Ranked Business Schools

Looking at tuition and fees alone, earning a business degree from a ranked program now costs more than $200,000 at 49 U.S. schools,

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Apr 19 • 4:07 PM EDT • Business • poetsandquantsforundergrads.com
Curing U.S. Health Care, Part I

In 2008, much to their own surprise, leading Democrats unified around a program of major health care reform. Policy wonks had spent years developing the concepts behind what eventually became Obamacare; big Democratic victories in the 2006 midterms and the prospect of controlling both Congress and the presidency made it possible to imagine turning those ideas into reality. During the Democratic primary, Hillary Clinton and Barack Obama advocated similar plans, based on those ideas, for expanding insurance coverage. And it happened! The Affordable Care Act was enacted in 2010. When it was fully implemented in 2014, millions of Americans got health insurance: Impressive as the raw numbers are, they don’t tell the whole story. Before the ACA, even upper-middle-class Americans often found it impossible to get health insurance if they had pre-existing medical conditions. Many Americans were trapped in jobs they wanted to leave but couldn’t for fear of losing their employment-based coverage. Meanwhile, dire predictions from the usual suspects about runaway costs proved wrong. In fact, overall U.S. medical spending has grown much more slowly since the ACA was enacted than before. But the U.S., alone among advanced nations, still falls far short of providing universal health care. As you can see from the chart above, 8 percent of the population was still uninsured in 2024, a number that is set to rise over the next two years as a result of Republican policies. True, many of the uninsured in 2024 were undocumented immigrants, who we don’t try to cover. But there are still a lot of uninsured. Moreover, a significant number of Americans who have health insurance are in fact underinsured. As a result, they are at risk of incurring devastating healthcare costs and are sometimes forced to forgo needed care. This number is set to rise sharply in the next two years as a result of Republican policies adopted under Donald Trump. And not only is the U.S. unique among advanced countries in its under-provision of health care coverage, it also incurs by far the world’s highest healthcare costs per capita. So now may well be a good time to get behind a new push for major health reform — an effort, if you like, to finish the job begun under Obama. Today’s primer is devoted to the economics of health reform. During his failed effort to repeal the Affordable Care Act, Donald Trump famously complained, “Nobody knew healthcare could be so complicated.” Actually, we did know — and it’s not that complicated. Health economists understand the principles very well. And because health policy varies greatly among advanced nations, we know a lot about what works and what doesn’t. This will be the first in a series about health reform. Beyond the paywall I’ll address the following: 1. Why markets can’t be trusted to deliver healthcare 2. Routes to universal healthcare 3. What works? In a follow-up post I’ll discuss the pros and cons of different approaches, and possible paths forward for the United States.

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Apr 19 • 6:31 AM EDT • Health • paulkrugman.substack.com
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Loneliness may be silently eroding your memory, new research reveals

New research suggests loneliness affects older adults' baseline memory performance but may not directly accelerate cognitive decline over time.

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Apr 18 • 8:33 PM EDT • Health • foxnews.com
Charlize Theron is 'not haunted' anymore by her mother fatally shooting her father: 'He was going to kill us'

"I think these things should be talked about because it makes other people not feel alone," the "Mad Max: Fury Road" star said in a new interview.

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Apr 18 • 1:36 PM EDT • Entertainment • yahoo.com
Scott Gaudin: Business owners don’t need a bank. They need a banker.

There is no shortage of banks—there are more than 4,500 nationwide. There is no shortage of products, platforms or capital in the market today. On paper, business owners have more options than ever before. And yet, many still feel like they are making important decisions alone. That is the problem. Business owners do not need […]

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Apr 17 • 3:30 PM EDT • Business • businessreport.com
Listen: With Little Federal Regulation, States Are Left To Shape the Rules on AI in Health Care

As artificial intelligence embeds itself into health care, some physicians and patient advocates worry it could be used by insurance companies to refuse payment for care. Maryland passed one law banning AI from acting alone on a denial. Meanwhile, Virginia’s then-governor vetoed that state’s attempt at regulating AI in health insurance.

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Apr 17 • 5:00 AM EDT • Health • kffhealthnews.org
Vance tells Pope Leo to ‘be careful’, Homan says ‘leave politics alone’

Senior Trump administration officials escalated criticism of the Vatican on Tuesday, with Vice President Vance warning Pope Leo XIV to “be careful” when speaking about theology and White House Bord…

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Apr 15 • 10:57 PM EDT • Politics • thehill.com
The history of popes and politics

Today on AirTalk: Popes and politics; L.A. City Charter reform proposals; Doing things alone; Will Gen Z save moviegoing? A chimpanzee civil war? and…

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Apr 15 • 11:51 AM EDT • Politics • laist.com
Republicans are moving to fund Homeland Security 'the hard way' after end of talks

Republicans in Congress are forging ahead with a risky go-it-alone strategy for funding the Department of Homeland Security | KMBZ

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Apr 14 • 5:54 PM EDT • Politics • audacy.com
UNC basketball under Michael Malone: Insiders reveal transfer portal news, 2026 recruits, roster, best targets

TarHeel247, the 247Sports affiliate of the North Carolina Tar Heels, shares its latest college basketball transfer portal news

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Apr 14 • 10:41 AM EDT • Sports • cbssports.com
UCLA makes WNBA draft history with record number of selections

Entering Monday night, UCLA had only produced six first-round draft picks since 1997. The program nearly matched that at the 2026 WNBA Draft alone.

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Apr 13 • 8:48 PM EDT • Sports • usatoday.com
2026 Bluebird Banter Top 40 Prospects: Matt’s Pref List

The last instalment in the Top 40 series on this off-day is my list of prospects I was somewhat higher on and would have either had on or in the mix for the back of my list alone. As Tom noted on his list, these are deep(er) sleepers, generally low probability, but usually they’re be […]

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Apr 13 • 1:16 PM EDT • Sports • sports.yahoo.com
‘Little House on the Prairie’: Netflix Reboot Debuts Teaser Trailer

'Even though they were all alone, they were happy because they were a family — and they were together.'

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Apr 13 • 12:25 PM EDT • Entertainment • cbs19news.com
Old Republic spins out TPA business as standalone brand after 30 years

Unit steps out from under PMA Companies with its own identity

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Apr 13 • 8:35 AM EDT • Business • insurancebusinessmag.com
Old Republic spins out TPA business as standalone brand after 30 years

Unit steps out from under PMA Companies with its own identity

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Apr 13 • 8:35 AM EDT • Business • insurancebusinessmag.com
‘I’m playing the long game’: Journalists are striking out alone and discovering the business is toughest beat of all

News Creators have become preferred sources for younger viewers, but how do they grow and sustain their independent endeavors?

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Apr 13 • 12:01 AM EDT • Business • digiday.com
Science 4 Everyone: Why aren't your plants growing back after the winter?

Are your plants not growing after winter? You aren't alone. Storm Team4 meteorologist Ryan Miller explains why winter conditions affect your plants.

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Apr 12 • 12:01 PM EDT • Science • nbcwashington.com
UNC basketball under Michael Malone: Insiders reveal transfer portal news, 2026 recruits, roster, best targets

TarHeel247, the 247Sports affiliate of the North Carolina Tar Heels, shares its latest college basketball transfer portal news

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Apr 12 • 10:57 AM EDT • Sports • cbssports.com
Chelsea Star Speaks On Exit From Manchester United

Garnacho, Chelsea Move Signals Reflection After Man United ExitThere is often a moment, quiet and uncomfortable, when a young footballer begins to understand that talent alone does not carry a career....

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Apr 11 • 11:50 AM EDT • Sports • sports.yahoo.com
XChat, X's standalone messaging app, launching on iPhone and iPad next week

XChat, the standalone messaging app from X, now has a release date. XChat will arrive on iPhone and iPad in...

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Apr 10 • 4:31 PM EDT • Technology • 9to5mac.com
Chimpanzees in Uganda are locked in a deadly 'civil war' after their group split apart — and scientists don't know why

The first well-observed "civil war" in wild chimpanzees reveals that shifting social ties alone can fracture a group, igniting deadly conflict between former friends.

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Apr 9 • 2:00 PM EDT • Science • livescience.com
SGMC Health Offers Safe Sitter® Classes to Promote Summer Safety for Children

SGMC Health will offer Safe Sitter® classes this summer to help prepare middle school students with the skills and confidence needed to stay safe while home alone, babysitting, or caring […]

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Apr 8 • 3:37 PM EDT • Health • sgmc.org
FedEx Freight sets goalposts for standalone business

FedEx Freight outlined financial targets and operational initiatives ahead of a June separation from parent FedEx Corp.

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Apr 8 • 1:35 PM EDT • Business • freightwaves.com
Viewpoint: FP10 should remain open, excellent and secure

Europe is right to worry about research security. Foreign interference is real. So is the misuse of sensitive knowledge. Universities working in sensitive areas such as AI, quantum, semiconductors and advanced materials cannot afford to ignore the geopolitical environment around them.But Europe is in danger of drawing the wrong conclusion, one that would increase, not reduce, its strategic vulnerabilities.If the EU applies an “EU preference” logic to the next Framework Programme for research and innovation (FP10), it will weaken one of its greatest strategic assets: a research system built on openness, excellence and international collaboration. In the name of security, Europe could end up advancing science more slowly, innovating less effectively and making itself less attractive to global talent and partners in advanced science and technology.That would be a serious mistake.The EU preference included in Article 10 of the proposed European Competitiveness Fund may make sense in some industrial or deployment contexts, but is far harder to justify when applied to collaborative research in advanced science and technology, where excellence and global connectivity are crucial. Research is not procurement. It does not thrive when isolated. It advances through access to the best ideas, the best people, the best facilities and the best data, wherever they are found. This is why FP10 should not simply absorb industrial policy logic by default. Doing so would risk importing instruments that are ill-suited to research and that ultimately increase vulnerability rather than resilience.For universities of science and technology, the issue is especially acute. These institutions sit at the frontier of knowledge and technology creation in the very fields Europe sees as critical for its future competitiveness and resilience. They know better than most that security risks are real. But they also know that openness and security are not opposites. In practice, they have to be made to work together. Research security is not about closing doors. It is about building resilience through collective responsibility, trust, proportionate safeguards and better governance. That is a fundamentally different approach from default restriction.The risks of non-collaborationThe real danger in the current debate is that Europe talks too much about the risks of collaboration and not enough about the risks of non-collaboration. Those risks are strategic too. Cut researchers off from international networks and Europe loses access to knowledge, data, infrastructures and talent. Slow down global collaboration in critical technologies and Europe slows down its own progress on cutting-edge science. Make participation rules unpredictable and Europe weakens its attractiveness to researchers and investors alike.In other words, over-restricting collaboration will create strategic vulnerabilities, particularly in advanced science and technologies.This point is often underestimated in policy discussions that frame openness mainly as a value to be defended. Europe’s scientific strength, technological development and long-term competitiveness depend on remaining connected to the best research ecosystems in the world. For a continent that wants to accelerate deep tech, strengthen industrial capacity and reduce strategic dependencies, weakening the excellence base would be self-defeating. That does not mean ignoring risk. Quite the opposite. Universities are already strengthening due diligence, internal governance, awareness-raising, screening procedures and compliance support. Across Europe, institutions are working to manage risks linked to foreign interference, sanctions, export controls and the misuse of research. The right response is not complacency. It is better risk management. But that means targeted, evidence-based and proportionate measures, not blunt top-down restrictions with wide spillover effects. In the daily reality of universities, openness and restriction often coexist. The real challenge is how to apply safeguards without sliding into securitisation that damages academic freedom, open science and international cooperation. Restrict partners, not nationsMore restrictive treatment of collaborators from European Economic Area members Iceland, Liechtenstein and Norway, or from Switzerland and the UK, is strategically very difficult to justify. These are deeply embedded partners in Europe’s research and innovation ecosystem. Beyond that, Europe should still resist default exclusion and instead rely on case-by-case assessment. The relevant question is not nationality in the abstract. It is the actual risk profile of a collaboration: the institution, the affiliations, the field, the knowledge involved, the intended use and the safeguards available. Screening should focus on institutions and affiliations rather than nationality alone. Related articlesParliament ‘misreads’ link between Horizon Europe and ECF, Commission official saysFrustration grows at governance gap in next Horizon EuropeIf EU preference logic is imported into research without careful calibration, the likely result is a chilling effect. Researchers may step back from legitimate and beneficial collaboration, even where risks are manageable. International partners may see Europe as less predictable. And Europe may end up undermining the very excellence base it needs to compete, scale up and lead in strategic technologies, thereby increasing its dependence on others.FP10 should do the opposite. It should remain open by default, with restrictions used only exceptionally, and then on the basis of clear evidence. It should integrate research security into open science and research integrity frameworks, not set them against each other. And it should recognise that academic freedom, scientific excellence and responsible international collaboration are not obstacles to Europe’s security, they are part of it. Europe needs stronger tools to protect itself. But it also needs the discipline to avoid measures that would weaken it and increase its strategic vulnerabilities in the process. In FP10, that means staying open, excellent and secure.Louise Drogoul is senior advisor for innovation and sustainability at the Cesaer university association.

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Apr 7 • 8:00 PM EDT • Science • sciencebusiness.net
It's Becoming Almost Impossible To Get A Mac Studio Or Mac Mini In 2026

Having trouble getting your hands on a Mac Studio or Mac mini in 2026? You're not alone, as both popular products are on long-term backorder.

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Apr 7 • 6:01 PM EDT • Technology • bgr.com
North Carolina to reportedly hire former Nuggets coach Michael Malone as Hubert Davis' replacement

Malone won an NBA championship with the Denver Nuggets during the 2022-23 season.

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Apr 6 • 3:35 PM EDT • Sports • sports.yahoo.com
North Carolina to hire Michael Malone as next basketball coach: Led Nuggets to NBA title in 2022-23

The Tar Heels have landed an unexpected hire as their next coach

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Apr 6 • 2:06 PM EDT • Sports • cbssports.com
Inside the mission to recover a downed American airman

Hiding alone in a mountain crevice behind enemy lines, the injured American airman knew exactly what to do: survive and evade.

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Apr 5 • 8:24 AM EDT • Politics • cnn.com
Deep dive
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Small Business Workshop on Social Media Marketing

If you’ve boosted posts and gotten little to no results, you’re not alone.

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Apr 4 • 7:50 PM EDT • Business • 2ndlifemediaalamogordo.town.news
I watched The Godfather again at 64 and cried — not because the movie changed, but because I finally understood that the films we watched in our twenties weren’t just entertainment, they were instruction manuals for masculinity, family, and honor that shaped every major decision I ever made

Last week, I found myself alone in my living room, remote in hand, scrolling through streaming options when The Godfather appeared on screen. It had been years since I’d watched it. Decades, really. Something made me click play, and three hours later, I was sitting there with tears streaming down my face. Not because Sonny […]

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Apr 4 • 6:00 PM EDT • Entertainment • vegoutmag.com
Trump's go-it-alone certainty confronts the uncertainties of war

President Donald Trump claims that the United States has, in his words, “completely decimated” Iran

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Apr 4 • 9:06 AM EDT • Politics • washingtonpost.com
Business News: Minerva Repositions In New Role As “Distinct Entity” Within Montblanc Brand

New watches will display the standalone Minerva name on the dial.

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Apr 3 • 3:00 PM EDT • Business • hodinkee.com
Gemma 4 and what makes an open model succeed

Having written a lot of model release blog posts, there’s something much harder about reviewing open models when they drop relative to closed models, especially in 2026. In recent years, there were so few open models, so when Llama 3 was released most people were still doing research on Llama 2 and super happy to get an update. When Qwen 3 was released, the Llama 4 fiasco had just gone down, and a whole research community was emerging to study RL on Qwen 2.5 — it was a no brainer to upgrade. Today, when an open model releases, it’s competing with Qwen 3.5, Kimi K2.5, GLM 5, MiniMax M2.5, GPT-OSS, Arcee Large, Nemotron 3, Olmo 3, and others. The space is populated, but still feels full of hidden opportunity. The potential of open models feels like a dark matter, a potential we know is huge, but few clear recipes and examples for how to unlock it are out there. Agentic AI, OpenClaw, and everything brewing in that space is going to spur mass experimentation in open models to complement the likes of Claude and Codex, not replace them. Especially with open models, the benchmarks at release are an extremely incomplete story. In some ways this is exciting, as new open models have a much higher variance and ability to surprise, but it also points at some structural reasons that make building businesses and great AI experiences around open models harder than the closed alternatives. When a new Claude Opus or GPT drops, spending a few hours with them in my agentic workflows is genuinely a good vibe test. For open models, putting them through this test is a category error. Something else to be said about open models in the era of agents is that they get out of the debate of integration, harnesses, and tools and let us see close to the ground on what exactly is the ability of just a model. Of course, we can’t test some things like search abilities without some tool, but being able to measure exactly the pace of progress of the model alone is a welcome simplification to a systematically opaque AI space. Share The list of factors I’d use to assess a new open-weight model I’m considering investing in includes: Model performance (and size) — how this model performs on benchmarks I care about and how it compares to other models of a similar size. Country of origin — some businesses care deeply about provenance, and if a model was built in China or not. Model license — if a model needs legal approval for use, uptake will be slower at mid-sized and large companies. Tooling at release — many models release with half-broken, or at least substantially slower, implementations in popular software like vLLM, Transformers, SGLANG, etc due to pushing the envelope of architectures or tools. Model fine-tunability — how easy or hard it is to modify the given model to your use-case when you actually try and use it. The core problem is that some of these are immediately available at release, e.g. general performance, license, origin, etc. but others such as tooling take day(s) to week(s) to stabilize, and others are open research questions — with no group systematically monitoring fine-tunability. In the early era of open models, the days of Llama 2 or 3 and Qwen pre v3.5, the architectures were fairly simple and the models tended to work out of the box. Some of this was due to the extremely hard work of the Llama, Qwen, Mistral, etc. developer teams. Some is due to the new models being genuinely harder to work with. When it comes to something like Qwen 3.5 or Nemotron 3, with hybrid models (either gated delta net or mamba layers), the tooling is very rough at release. Things you would expect to “just work” often don’t. I’ve been following this area closely since we released Olmo Hybrid with a similar architecture, and Qwen 3.5 is just starting to work well in the various open-source tools that need to all play nice together for RL research. That’s 1.5 months after the release date! This is just to start really investing more into understanding the behavior of the models. Of course, others started working on these models sooner by investing more engineering resources or relying on partially closed software. The fully open and distributed ecosystem takes a long time to get going on some new models. All of this is lead-in for the most important question for open models — how easy is it to adapt to specific use-cases? This is a different problem for different model sizes. Large MoE open-weight models may be used by entities like Cursor who need complex capabilities in their domain, e.g. Composer 2 trained on Kimi K2.5. Other applications can be built on much smaller models, such as Chroma’s Context-1 model for agentic search, built on GPT-OSS 20B. The question of “which models are fine-tunable” is largely background knowledge known by engineers across the industry. There should be a thriving research area here to support the open ecosystem model. The first step is to understand characteristics of different base and post-trained models to understand what they look like. The second step is to tune pretraining recipes for open models so they’re more flexible. Interconnects AI is a reader-supported publication. Consider becoming a subscriber. Subscribe For The ATOM Project and other Interconnects endeavors, we’ve put in substantial effort to measuring adoption trends in the open ecosystem. Everything takes a long time to unfold after a model is first publicly available — and adaptability is why. What we know for sure now, when Qwen has been going from strength to strength with its releases, is that technical staff across the industry has gotten comfortable working with Qwen models. Countless research methods and datasets were made to work with Qwen. It’ll take patience for any other model family to get to this point — a patience I’m not sure many open model builders have. This takes us to Gemma 4, Google’s latest open models. Gemma 3 was released more than a year ago, in March of 2025, and is a bit underrated. Gemma 4 comes in 4 sizes for now, with a bigger, MoE model of over 100B total parameters rumored but not released yet. The models we have today come in sizes of ~5B dense, 8B dense, 26B total 4B active MoE, and 31B dense. I’m most excited that they’re finally adopting a standard Apache 2.0 open source license. This’ll massively boost adoption. The standard of better licenses for strong open-weight LLMs was set by mostly Chinese open model labs in the last 1-2 years, and now U.S. companies are following suit. I will personally be so happy if the horrible Llama licenses and Gemma terms of service were an ~18-month transient dynamic of the industry being nervous about releasing strong open models. The Gemma 4 scores look very solid, the small models have incredible benchmark scores (especially in general domains like LMArena) and the 31B model rivals the recent Qwen 3.5 27B, which is the leading member of that class. The ~30B size range is an important one, as it’s accessible both to researchers and to enterprises looking to deploy the model in real use-cases. Where the 7B model scale is the default for tinkering and research, a 30B model is the default for seeing if an open model can unlock substantial value in your specific workflow — a good mix of intelligence, low price, tractability for downstream training, etc. This takes us back to the above adoption criteria I mentioned for open models and the bigger question — do I think Gemma 4 will be an overwhelming success? Previous Gemma models have been plagued by tooling issues and poorer performance when being finetuned. Gemma 4’s success is going to be entirely determined by ease of use, to a point where a 5-10% swing on benchmarks wouldn’t matter at all. It’s strong enough, small enough, with the right license, and from the U.S., so many companies are going to slot it in. I’m cautiously optimistic that Gemma 4 is going to work better here. Winds are shifting for open models built in America. We saw GPT-OSS go through a bumpy launch to become an overwhelming success. There’s a collective energy around the likes of Reflection, Arcee, Nemotron, Gemma, Olmo, and peers that show substantial demand for building new stacks around open models. There’s capital to be spent on AI stacks across the economy by those who want more ownership of everything, including the model. After launching The ATOM Project 240 days ago, the conversation is shifting into the next stage. Summer of 2025 was a crisis moment where the U.S. AI scene realized it can’t wait and figure out open models after building AGI. The two markets will capture different areas and proceed in parallel. Now that more companies in the U.S. are releasing strong models, we need to improve the ecosystem so that these models are easy to use, understand, and build value around. It’s the hard work to build another inflection point in these adoption plots I’ve been updating consistently, but that’s the work to be done. Join me in it. More data coming soon! Here’s a sneak peek:

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Apr 3 • 12:57 PM EDT • Technology • interconnects.ai
Faculty spotlight: The unlikely path to building UVA’s newest school

Brian Wright didn’t expect to end up in the data science field, let alone helping lead a school.

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Apr 3 • 11:08 AM EDT • Science • news.virginia.edu
iPhone 17e vs. iPhone 17 Buyer's Guide: 35+ Differences Compared

The iPhone 17e and iPhone 17 are among the most affordable iPhones in Apple's current lineup, separated by just $200, but the gap between them is more significant than the price difference alone suggests. The $599 iPhone 17e is Apple's budget-first option, built around the efficient C1X modem and a single-camera system.

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Apr 1 • 11:21 AM EDT • Technology • macrumors.com
Why Health Taxes Alone Won't Fix Malnutrition in Poor Countries

Health taxes on sugar seem to have captured the zeitgeist: Mexico's soda tax, the UK's sugar levy, South Africa's Health Promotion Levy, a sugar tax in the Philippines, and so on. The evidence on these policies suggests real benefits: (1) reduced consumption of sugary drinks, (2) measurable revenue for governments, and, (3) in theory, a nudge toward healthier choices. But the conversation is increasingly moving past sugar with increasing calls for health taxes on so-called ultra-processed foods.

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Apr 1 • 8:00 AM EDT • Health • cgdev.org
Shakira says she feels like she's just getting started. A Rock Hall nomination begs to differ

Shakira says her new world tour is turning lifelong dreams into reality as she sets attendance records and earns major recognition. The boundary-breaking Colombian performer told The Associated Press she

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Mar 31 • 8:00 AM EDT • Entertainment • calonews.com
Lauren Book to launch 11th annual ‘Walk in My Shoes’ trek across Florida

'For eleven years, we have walked across Florida to shine a light on child sexual abuse and to remind survivors they are not alone.'

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Mar 30 • 4:15 AM EDT • Politics • floridapolitics.com
How the 5Cs of credit help Nevada small businesses access capital

Looking for capital for your Nevada small business? You’re not alone.

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Mar 29 • 10:00 PM EDT • Business • vegasinc.lasvegassun.com
Cuba is not alone, deputy FM says as US threats grow
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Mar 29 • 3:06 PM EDT • Politics • aljazeera.com
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Windows 11’s push for mandatory Microsoft accounts is hitting a nerve with users who say the change complicates setup, privacy, and basic PC ownership

The mandatory Microsoft account requirement in Windows 11 is a drag, and I can only hope it one day goes away. I'm not alone.

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Mar 29 • 9:12 AM EDT • Technology • windowscentral.com
Chris Kelly Opinion: A petition for better acting in politics and PR

“Memory, all alone in the moonlight/ I can dream of the old days/ Life was beautiful then…” – from “Memory,” by Andrew Lloyd Webber Successful theatrical productions achieve the “suspension of disbelief,” temporarily convincing audiences th…

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Mar 29 • 5:00 AM EDT • Politics • thetimes-tribune.com
You're not alone: Most users are disappointed with the Galaxy S26 Ultra – here's what Samsung could ...

More was expected from the S26 Ultra.

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Mar 28 • 5:03 AM EDT • Technology • phonearena.com
LA Artisteada podcast’s live ‘Take the Stage’ celebrates female artists

This Sunday, March 29, LA Artisteada, a podcast dedicated to spotlighting a wide range of artistic voices, will host “Take the Stage”, a live event creating space for women of

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Mar 27 • 10:00 AM EDT • Entertainment • calonews.com
Transcript: How Democrats Can Defeat Trump’s Identity Politics

Author Justin Gest says that economic policy alone won’t defeat the far-right in the United States and Europe.

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Mar 26 • 8:00 PM EDT • Politics • newrepublic.com
How Democrats Can Defeat Trump’s Identity Politics

Author Justin Gest says that appealing to voters’ sense of belonging and identity is essential and can’t be done with economic policy alone.

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Mar 26 • 8:00 PM EDT • Politics • newrepublic.com
Startups juice carbon removal with power generation

The era of relying on carbon removal revenue alone is over.

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Mar 25 • 1:45 PM EDT • Business • axios.com
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March Madness 2026: Our experts reset their NCAA Tournament brackets with updated picks heading into Sweet 16

If your bracket is busted, you are not alone, so here's what our experts would do if given a chance to reset their predictions

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Mar 25 • 12:34 PM EDT • Sports • cbssports.com
Glyphosate: A story of science, risk, and nuance

In the summer of 2014, a California groundskeeper named Dewayne Johnson started noticing patches of raw, weeping skin spreading across his body. He had spent years applying Roundup, Monsanto’s glyphosate-based herbicide, for a school district, sometimes drenched in it when equipment malfunctioned. By 2014, he had a diagnosis: non-Hodgkin’s lymphoma. In 2018, a jury awarded him $289 million in damages, later reduced on appeal. Tens of thousands of lawsuits followed. The story hasn’t quieted down. It’s all over the internet, swinging between “this will kill you, buy organic” and “relax, you’re fear-mongering.” Some of that recent chatter stems from an Executive Order protecting glyphosate and its production, which set off intense infighting within the MAHA movement. Some of it reflects a deeper truth: Americans genuinely care about harmful chemicals in their environment (see poll below). And the conversation isn’t going anywhere, with a Supreme Court case involving Monsanto set for this April. Glyphosate (the active ingredient in Roundup) is one of the most widely used herbicides in the world. But does glyphosate cause cancer? And how much exposure is actually risky? With so much mistrust in institutions and corporations (and some genuine conflicts of interest), making sense of the actual scientific evidence is genuinely hard. Here is a translation of what the scientific evidence actually says. Does glyphosate cause harm? Glyphosate is an herbicide that kills most plants it contacts rather than targeting specific species. It works by blocking an enzyme pathway (EPSPS) that plants and many microorganisms need to produce essential amino acids. Without those amino acids, the plant can’t grow and dies. Glyphosate was first developed by Monsanto in the 1970s and became ubiquitous after the company introduced “Roundup Ready” crops in the 1990s. In 2024, Bayer removed glyphosate from residential Roundup-branded products due to litigation pressure. But today it is still the most widely used herbicide in the world. Farmers also discovered they could spray it directly on crops like oats, lentils, beans, and peas just before harvest to dry them out faster and make harvesting easier. Because of its widespread use, it’s obviously really important to understand if it’s harmful to humans. The key principle: The dose makes the poison The most important concept in toxicology is that “the dose makes the poison.” Sixteenth-century physician Paracelsus articulated what remains the foundational principle of toxicology: sola dosis facit venenum. Water will kill you if you drink enough of it. Aspirin saves lives at 81 milligrams and causes internal bleeding at higher chronic doses. So, at what dose is glyphosate poisonous? The LD50 in rats (the dose that kills half the test animals) is around 5,600 mg/kg body weight. Table salt is roughly 3,000 mg/kg. By that classic measure, glyphosate is less acutely toxic than salt. But some people are exposed to a lot of glyphosate through their work. And among the general public, there are many questions about low-dose, cumulative exposure from multiple sources over long periods. Does glyphosate cause health problems? Cancer Correlation maps are striking, with one analysis finding that 60% of counties that spray the most glyphosate have non-Hodgkin’s lymphoma rates above the national average. But correlation alone doesn’t establish cause, which is why animal and human studies matter. In animals: Rat studies are typically what most fear is rooted in, but most people don’t know the study details on the dosage given to rats. A pooled analysis of the 13 most rigorous rat studies found evidence that very high doses, around 55,000 times greater than typical food residue exposure, can cause certain cancers. In humans: One of the strongest studies followed 55,000 herbicide users over 20 years and found no overall increased cancer risk. There was one signal: among those with the highest use, rates of acute myeloid leukemia (AML) appeared elevated. A broader meta-analysis of 18 human studies also found no overall cancer risk, though a separate meta-analysis focused specifically on non-Hodgkin lymphoma found that people with high cumulative glyphosate exposure faced a 41% higher relative risk compared to those with low or no exposure. These human studies are observational studies (randomized controlled trials would be unethical), and meta-analyses are only as reliable as the studies they pool. But the story seems consistent: at very high exposure levels, there may be some cancer risk. But that’s about as far as the science currently takes us. Emerging research: gut and reproductive health Gut: Because glyphosate targets a pathway that exists in some gut bacteria, scientists have questioned whether it could affect the microbiome. In mice, a 2023 University of Iowa study found that glyphosate altered gut bacterial composition and raised markers of intestinal inflammation. A 2024 systematic review found similar patterns: disrupted gut bacteria and problems with the mucus layer that protects the intestinal wall in mice. Whether this translates to humans is an open question. The human gut is highly variable and resistant, and we don't yet have strong studies confirming the same effects in people. Reproductive health: Animal studies have found that glyphosate-based herbicides can interfere with reproductive hormones, including disrupting egg cell development in mice and reducing the number of eggs available in sheep’s ovaries. However, the doses used in these experiments were high, so it’s not yet clear whether the same effects would occur in humans. On the human side, a 2021 pilot study led by Mount Sinai researchers tested urine samples from pregnant women across the U.S. and found glyphosate in 95% of them. The study also found a possible connection between higher glyphosate exposure during pregnancy and a subtle physical difference measured in female newborns. That said, some connections weren’t statistically reliable and this was a small study. The researchers themselves said more and larger studies are needed before drawing firm conclusions. What do regulators say about glyphosate safety? In 2015, the International Agency for Research on Cancer (IARC), part of the World Health Organization, classified glyphosate as "probably carcinogenic to humans" (Group 2A). The classification is worth taking seriously. But, there’s an important distinction: IARC classifies hazard, meaning the potential to cause harm under some conditions. It does not assess risk, which accounts for actual exposure levels and the real-world probability of harm. The U.S. EPA, the European Food Safety Authority, Health Canada, and regulatory agencies in Australia and Japan have all concluded that glyphosate is “unlikely to be carcinogenic to humans” at realistic exposure levels. They’re asking a different question: given how much of this people actually encounter, what is the probability of harm? Your actual exposure is what determines your actual risk. What does glyphosate mean for your daily life? At the grocery store: Food residues are small. The EPA’s acceptable daily intake is 1.75 mg/kg of body weight per day. To hit that threshold from oatmeal alone, a 150-pound adult would need to eat roughly 50 pounds of oats every day. But this calculation addresses only one pathway (food), and we don’t yet have robust tools to measure people’s actual total exposure. If reducing exposure matters to you, organic certification prohibits synthetic herbicides, and organic oat products generally test at lower or undetectable levels. Either way, a diet rich in whole grains, conventional or organic, is far better for your health than one that omits them out of fear of residues. On the farm: Occupational exposure is orders of magnitude higher than consumer exposure. Farmers and farm workers who mix, load, and apply glyphosate-based herbicides, especially without protective equipment, face meaningfully different risk profiles. Proper PPE isn’t optional. Integrated weed management strategies that rotate chemical modes of action are also worth taking seriously, both for health and for long-term effectiveness. If you live near a farm: Spray drift is real. Concentrations near field edges can spike during and after application, particularly on windy days. This is an area where I think public health could really step up and empower rural communities with buffer zones, rather than placing the onus on individuals. But for now, knowing your local agricultural calendar and keeping windows closed during application are the first steps. Bottom line Dewayne Johnson was exposed to glyphosate at levels most people will never encounter, and a jury decided he deserved compensation. That outcome is not evidence that the oatmeal in your pantry is dangerous. But it is a reminder that the dose, the context, and the person doing the exposing all matter enormously. Glyphosate is a chemical tool with benefits, trade-offs, and genuine open scientific questions. Learning to hold that complexity without collapsing into panic or dismissal is, honestly, one of the most useful and hardest things to do in navigating modern health science. Love, YLE Your Local Epidemiologist (YLE) is founded and operated by Dr. Katelyn Jetelina, MPH PhD—an epidemiologist, wife, and mom of two little girls. Hannah Totte, MPH, is an epidemiologist and YLE Community Manager. YLE reaches more than 425,000 people in over 132 countries with one goal: “Translate” the ever-evolving public health science so that people will be well-equipped to make evidence-based decisions. This newsletter is free to everyone, thanks to the generous support of fellow YLE community members. To support the effort, subscribe or upgrade below: Subscribe

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Mar 25 • 10:25 AM EDT • Science • yourlocalepidemiologist.substack.com
iOS 27 Siri Overhaul: Standalone App, New Design, Dynamic Island Integration and Ask Siri Button

Apple is testing a standalone Siri chatbot app for iOS 27, reports Bloomberg's Mark Gurman. Apple plans to debut a chatbot version of Siri that will compete with Claude and ChatGPT, and the new Siri could be accessible through a dedicated app. Gurman previously said that Apple was not going to develop a standalone Siri app, but it appears plans have changed.

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Mar 24 • 3:22 PM EDT • Technology • macrumors.com
Apple Plans AI Reboot With Siri App, New Look and ‘Ask Siri’ Button in iOS 27

Apple Inc. is testing a standalone app for its Siri voice assistant alongside a new “Ask Siri” feature that will work across the company’s software, part of a broader artificial intelligence overhaul.

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Mar 24 • 2:49 PM EDT • Technology • bloomberg.com
Josh Shapiro endorses James Malone in key Lancaster County Senate race

Gov. Josh Shapiro has officially endorsed James Malone’s bid for reelection in the Lancaster County state Senate district that both parties say could determine party control next year.

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Mar 24 • 5:00 AM EDT • Politics • lancasteronline.com
The reality of death and the Trinitarian “science” of salvation

Readings: • Ez. 37:12-14 • Psa. 130:1-2, 3-4, 5-6, 7-8 • Rom. 8:8-11 • Jn. 11:1-45 We live in a time of astounding scientific breakthroughs and unprecedented medical marvels. In my lifetime alone, we’ve witnessed men landing and […]

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Mar 21 • 12:00 PM EDT • Science • catholicworldreport.com
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From Project Hail Mary to Saturday Night Live UK: your complete entertainment guide to the week ahead

Scientist Ryan Gosling is alone in deep space – or is he? – and America’s famed topical satire is given a British angle

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Mar 21 • 2:00 AM EDT • Entertainment • theguardian.com
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New dispute emerges around Subnautica 2’s early access release

Lawyers for the ousted—and now partially reinstated—leadership team of Unknown Worlds, the studio behind Subnautica 2, are crying foul over news that the game will be released into early access in May. The release announcement earlier this week was made improperly, potentially “damaging the game and sowing additional confusion among the Subnautica community,” the lawyers said in a letter sent on Tuesday to Vice Chancellor Lori Will of Delaware’s Court of Chancery. In their letter, the lawyers also floated the idea of asking Will to find Krafton in contempt of the court’s ruling. The letter was sent just one day after Will’s bombshell ruling that publisher Krafton had breached its contract with Unknown Worlds’ executive team, when it fired them last June. The new issue isn’t necessarily the May early access timeframe, but how the news was announced. The letter and Krafton’s response have not been previously reported. A quick recap of prior events: Subnautica 2 is an unreleased, underwater survival adventure and the most-wishlisted game on Steam. Last year, longtime Unknown Worlds CEO Ted Gill, along with studio co-founders Charlie Cleveland and Max McGuire, were fired by Krafton. They swiftly sued, saying the publisher had terminated them to avoid paying out up to $250 million in potential performance-based bonuses. The studio leaders had hoped to earn that with an early access release of the game, which Krafton had blocked. The publisher argued in court that Subnautica 2 wasn’t ready, which the ousted execs disputed. On Monday, Will ruled that Krafton had violated its contract, firing the execs to avoid the performance payouts, and that it had to reinstate Gill and give him full authority over any early access release for Subnautica 2. On Tuesday, IGN reported on a new memo issued that day to Unknown Worlds staff by Steve Papoutsis, the executive Krafton had put in charge of Unknown Worlds after the 2025 firings. In the note, Papoutsis said that Subnautica 2 had passed a key development milestone “last week” and that he and Krafton had determined the game “is ready for Early Access release in May.” This news appeared to catch the lawyers for Gill, Cleveland and McGuire by surprise. On Tuesday night, they sent a letter to Will expressing “serious concerns” about whether it would be possible to forge an agreement with Krafton consistent with the judge’s order. Papoutsis’ memo was a problem, they wrote. He didn’t have the authority to declare anything about Subnautica 2’s release. As of 9am ET on Monday, March 16, the effective date of Will’s order, Papoutsis wasn’t CEO of Unknown Worlds. Gill was. And, per Will’s order, only Gill could make Subnautica 2 release decisions. They continued: Krafton self-servingly announced the launch without any regard to its impact on the game, the team, or the community—let alone this Court’s Opinion. Announcing the release of a game is momentous, and it is typically accompanied by significant marketing activity, fanfare, and community coordination. And most importantly, the announcement is carefully designed to maximize excitement for the game. That entire process was supposed to be driven by Mr. Gill. However, in defiance of the Court’s Opinion, Krafton has now taken that away, further damaging the game and sowing additional confusion among the Subnautica community. The lawyers speculated that Krafton had “intentionally leaked” Papoutsis’ memo and then issued an official statement to confirm the leak. Game File is a reader-supported publication. My reporting is only possible through support from readers like you. To support my work, consider becoming a free or paid subscriber. Subscribe On Wednesday, lawyers for Krafton defended their client in their own letter to vice chancellor Will, saying nothing they did violated her order nor showed contempt: Papoutsis’s message was simply celebrating the UW employees’ efforts toward a past event: Krafton’s pre-Opinion determination that Subnautica 2 was ready for Early Access release. There was nothing improper about conveying the results of the milestone review or thanking the development team for their dedication and talent. They added that Gill could still make his own call about Subnautica 2’s release: In his role as CEO, Gill will be able to assess independently his views on the state of Subnautica 2 and the appropriate release schedule; nothing in Papoutsis’s message alters Gill’s authority or discretion. Vice chancellor Will has not responded to the letters and doesn’t necessarily have to. Both parties were previously ordered by Will to confer this week and submit a proposed judgment consistent with her ruling. The letter from Gill’s attorney’s this week doesn’t indicate whether he would or would not support a May release for Subnautica 2. But it could limit his options. And, if Gill’s lawyers are right, the lack of marketing fanfare around the leak of the May date could dull the launch of the game. Any harm to Subnautica 2’s launch is an extra sensitive issue given the context of the legal dispute: millions of dollars of payouts are on the line, tethered to the scale of the game’s initial performance. In her ruling on Monday, Will noted that there was obvious “bad blood” between Gill’s side and Krafton but that the two would need to work together: “They can—and must—act in good faith to navigate their remaining contractual relationship.” Item 2: A new kind of couch co-op game A highlight of GDC each year is the Alt.Ctrl showcase that features games played with extremely experimental controllers. Perusing this year’s offerings last Friday, I found a game controlled with giant scissors, another with big toothbrushes and one that amounted to dumpster diving. My favorite was Pivot, a co-op game about collectively maneuvering a couch. It was developed by students at the University of Utah’s masters of arts and engineering games program. Players lift and tilt the physical couch in order to control the position of a virtual one. That virtual one is moving through an obstacle course on-screen, while being pursued by a giant skull. Developer Nishant Verma told me at GDC that the couch is made of styrofoam (this became more evident as I watched!) and that the name was a riff on an episode of the sitcom Friends. Item 3: In brief… 🚫 Ubisoft is laying off more than 100 workers at its Red Storm studio, as the North Carolina location known for decades for its Tom Clancy games, ceases in-house game development, VGC reports. 👀 On Monday, Nvidia’s revealed its DLSS 5 AI-driven graphics technology that purports to improve game graphics… and it has been roasted about it by the media and the online gaming public for the remainder of the week. The tech changed the faces of characters in footage from Resident Evil Requiem, Hogwarts Legacy and EA Sports FC, drawing accusations of giving carefully art-directed games the generic look of AI “slop.” Nvidia CEO Jensen Huang had said on Monday that “DLSS 5 is the GPT moment for graphics—blending handcrafted rendering with generative AI to deliver a dramatic leap in visual realism while preserving the control artists need for creative expression.” By mid-week, Huang was telling Tom’s Hardware that the new tech’s critics were “completely wrong” because game-makers could still “fine-tune the generative AI” to suit their game’s aesthetics.

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Mar 19 • 5:28 PM EDT • Technology • gamefile.news
German Health Minister Nina Warken and WHO Hub in Berlin highlight 2025 achievements

Germany’s Federal Minister of Health, Nina Warken, visited the WHO Hub for Pandemic and Epidemic Intelligence in Berlin today to review progress and launch its 2025 Annual Report. The report highlights advances in using artificial intelligence, data science and pathogen genomics to strengthen global preparedness for future pandemics.In 2025, the WHO Hub in Berlin worked with more than 160 Member States and over 190 partners to help countries and organizations develop new systems and tools to detect and understand new public health threats as quickly as possible, whenever and wherever they occur.BMG to confirm whether they wish to contribute a quote. “Detecting outbreaks early is one of the most effective ways to save lives and prevent epidemics from becoming global crises,” said Federal Minister of Health Nina Warken. “Germany is proud to host and support the WHO Hub for Pandemic and Epidemic Intelligence. Its work strengthens our safety at home and helps protect people worldwide.”Artificial intelligence is increasingly transforming the detection of outbreaks. In 2025, the Hub launched an upgraded version of the Epidemic Intelligence from Open Sources (EIOS) system, which uses enhanced AI functions to scan global online information in real time and help experts quickly identify unusual health events. The system is now used by 120 countries.To better anticipate health threats, countries need information beyond traditional health data. The Hub supports countries in implementing Collaborative Surveillance, which integrates data on climate, animals, travel, and population movement to provide a more comprehensive and real-time understanding of health threats.The Hub also expanded global access to pathogen genomics, which helps scientists detect new pathogens, such as viruses and bacteria, understand how they spread and how dangerous they may become. Through the International Pathogen Surveillance Network (IPSN), the WHO Hub in Berlin worked with 309 partners in 101 countries to expand access to these technologies.“We are in a new era of global health threats, and we need new tools to face tomorrow’s challenges,” said Dr Chikwe Ihekweazu, Executive Director of the WHO Health Emergencies Programme. “The WHO Hub in Berlin helps countries use data and technology more effectively so they can identify risks earlier and respond faster. No country can address these threats alone. Strong cooperation remains our best defence.”“Berlin offers an ideal environment for our work. We collaborate closely with world-leading institutions such as the Robert Koch Institute and the Charité Center for Global Health,” said Dr Oliver Morgan, Head of the WHO Hub for Pandemic and Epidemic Intelligence. “Germany has supported the WHO Hub since its establishment, and we are pleased to welcome Federal Minister Nina Warken to the Hub today. This strong partnership helps us advance innovation in pandemic and epidemic intelligence and better support countries to prepare for future health threats.”The Hub is expanding the use of advanced analytics and mathematical modelling to forecast how outbreaks may develop and to assess which response measures are most effective. Through its Collaboratory, the Hub connects modelers and analysts with governments to ensure their work addresses real public health needs. In 2025, the community grew to 1300 members from 50 countries and 200 institutions. An AI-powered pandemic simulator, currently in the prototyping phase, will help decision-makers compare outbreak scenarios and help identify effective disease control measures.

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Mar 19 • 8:00 AM EDT • Health • who.int
This heart-healthy diet may also lower the risk of dementia

Two studies have found the DASH diet — either alone or combined with the Mediterranean diet — is a winner in terms of brain health.

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Mar 19 • 6:00 AM EDT • Health • washingtonpost.com
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Mar 17 • 1:06 PM EDT • Sports • youtube.com
Alibaba shakeup hints at an AI business model

The $325 bln group ‌is separating its AI initiatives from its cloud computing unit. It’s a nod to a craze for digital agents like OpenClaw and willingness of consumers to pay for these standalone services. Monetising AI will remain daunting but the rejig makes sense.

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Mar 17 • 12:58 AM EDT • Business • reuters.com