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Rural Health Transformation Project funding could bring childcare to Juneau hospital workers
A Juneau nonprofit received grant funding to create a childcare center for Bartlett Regional Hospital employees.
D'Aneglo Russell Could Make Sense for Trail Blazers
Fresh off his Memphis release, the veteran playmaker offers Portland low-risk backcourt depth and elite shot-creation to fortify a roster suddenly aiming for a Western Conference playoff run.
Florida business owners say minimum wage increase could help retain Alabama workers
Supreme Court Ruling Could Have Limited Impact on Voter Screening in Midterms
Federal law requires a 90-day “quiet period” before elections, likely restricting the immediate scope of a decision that allows the use of a citizenship database to examine voter rolls.
Could New York use expanded federal voter citizenship database?
New York election officials can now choose to use an expanded federal database to verify the citizenship of people on voter rolls.
White House claims pro-Trump ad it paid Fox to air was ‘public service announcement’
Some Democrats say taxpayer-funded ad could be illegal government propaganda aimed at influencing voters
White House has not acted on RFK Jr.’s push for proof ultra-processed foods are safe
A draft letter obtained by The Post shows Kennedy’s favorable response to a petition that food experts said could lead to significant changes for the industry.
Family of paralyzed Marine vet allegedly shot by migrant speaks out as health issue could delay testimony
Jimmy Friesenhahn, a Marine veteran paralyzed in a San Antonio shooting, faces a health crisis before trial, his family told Fox News Digital.
Eye of the Tiger: Pivotal position matchups vs. Texas A&M
Which specific matchups could be key on Saturday night?
Proposed business park south of Durango could noticeably increase county’s share of manufacturing jobs
Strategic plan calls for nearly 1.2 million square feet of commercial and industrial space over 21 years
Liverpool could sign Everton's best player next summer
Liverpool haven’t signed a player directly from Everton since Abel Xavier crossed Stanley Park in 2002, but that record could soon be broken. There are always rumours linking the Reds with whoever i...
Dan Dickman’s legacy takes center stage at 2026 Business Appreciation Luncheon
Dan Dickman's influence was unmistakeable at the 2026 Business Appreciation Luncheon. Many remembered Dickman as a mentor, advocate and community leader who helped people see a path forward when they could not see one themselves.
NASA teases new PRIMA telescope that could peer even deeper into the infrared universe than the James Webb Space Telescope
NASA has announced that a new telescope concept called PRIMA is moving forward in consideration for a 2033 launch to look at the origins of planets and galaxies.
The business case for pacing AI
Spacing out model launches and more efforts on safety could spur wider business adoption - if the political support is there.
Brandi Glanville says health battle forced her to spend 'hundreds of thousands'
Reality star Brandi Glanville explains why her recent financial strain made turning down opportunities more difficult and pushed her to prove she could perform again on FOX's "Special Forces."
Manchester City Could Pay a Bigger Price Than Any Sanction
Manchester City could face a much harsher penalty than just financial sanctions following the stunning news on Friday. The post Manchester City Could Pay a Bigger Price Than Any Sanction appeared first on HEAVY.
Barcelona could reignite pursuit of Sporting star in January
The board at La Liga giants Barcelona are giving consideration to reigniting their chase of Sporting CP star Luis Suárez following the turn of the year.That’s according to Spanish outlet Fichajes, ...
Oceans Calling cancels entire festival as storm silences Ocean City event
BALTIMORE — Oceans Calling canceled the rest of its three-day festival Friday, ending hopes that crews could overcome worsening wind and beach erosion to stage shows Saturday and Sunday at
Oceans Calling cancels entire festival as storm silences Ocean City event
BALTIMORE — Oceans Calling canceled the rest of its three-day festival Friday, ending hopes that crews could overcome worsening wind and beach erosion to stage shows Saturday and Sunday at
Discovery could help older adults maintain muscle strength
A groundbreaking discovery could help older adults maintain the muscle strength they need to stay active and independent.
Voters are turning to AI on politics. Is it up to the task?
Artificial intelligence is playing a growing role in how voters get information about politics and elections, raising fresh questions about how the technology could influence the way voters stay in…
Earth microbes survive simulated conditions of Saturn moon’s ocean
Experiment suggests organisms could live in harsh environment under Enceladus’s icy crust, strengthening possibility moon could support life
Rocks from Pompeii suburb tells a story of destruction—that could help us today
Chemistry and first-person sources are joining forces to date eruptions.
Why the 2026 election could be the worst midterm for the GOP this century
The Republican Party’s two worst midterm elections in the 21st Century were in 2006 and 2018. In the former, an unpopular Middle Eastern war cost George W. Bush dearly. In 2018, voters balked at the upending of historic norms and chaotic style of a new president named Donald Trump.
Bill Gates warns AI could lead to 'a billion deaths'
The cofounder of Microsoft made grave predictions about AI and voiced support for government regulation of the sector.
Report: Cubs, Red Sox Could Finish Series In Tampa
As a looming nor’easter forces scheduling shifts and doubleheaders, the regular-season finale faces a potential relocation to Tropicana Field to bypass Boston’s worsening weekend weather forecast.
The 5 College Football Games to Watch in Week 4
Before diving in, please note that Big Ten games are not included below since they are covered in our weekly Big Ten preview. Clemson at Cal 10:30 p.m., ESPN (Friday) This may not be worth the late-night viewing, but this game could answer two interesting questions — is Dabo Swinney’s time at Clemson coming to […]
Sherrill wants Caldwell to resign. If he stays, lawmakers may face an impeachment fight.
If he remains in office, the controversy could continue limiting her ability to travel outside New Jersey while intensifying pressure on lawmakers to consider impeachment.
Montgomery County business owner pleads guilty in SEPTA bid-rigging case
A former Montgomery County business owner could face prison after pleading guilty in a SEPTA bid-rigging scheme.
Texas vs Tennessee: Which program is the real UT?
The Top 25 battle for the real UT could be decided.
Supreme Court allows Trump administration to use expanded database for potential voter purges
Critics have said the data could lead to U.S. citizens being kicked off the voter rolls, but the justices noted the law prohibits broad voter purges in the weeks leading up to an election.
Dodgers could be foiled by familiar foe
Seeing the booze-drenched celebration around him through the tinted lenses of his eyewear, Manny Machado suddenly recalled he’d done this before.
'Everything we know about space travel is going to change within a decade': The fusion breakthrough that could unlock a path to the stars
Several companies have made significant headway toward nuclear fusion propulsion drives. Is humanity on the brink of a revolution in spaceflight?
College football has never been better. So why are its leaders set on a 24-team playoff that could ruin the sport?
Anton Johansson Had One Rule in His Sidney Crosby Encounter
Detroit Red Wings prospect Anton Johansson addressed his earlier preseason encounter with Sidney Crosby and explained why he could not back down.
The Packers' struggles could be the Jets' gain
Politely, Taylor Swift Could Have Skipped the Encore
Taylor Swift just released "The Life of a Showgirl: The Encore." Here, a lifelong fan dives into why the pop star could have skipped the curtain call.
Proposed Changes to Demographic Data Collection in the Census Could Impact Efforts to Address Health and Health Care Disparities
This issue brief provides an overview of the decennial census and discusses potential implications of the changes outlined in a September 2026 proposed rule to prohibit the collection of race and ethnicity data on the census and exclude many noncitizen immigrants from the apportionment count.
McDonald’s may get into the advertising business
The fast-food giant is testing a commerce media network, saying it could be a $1 billion business.
Grizzlies' Most Realistic 2026-27 Outcome Could Be Ideal
The Grizzlies may hover around the Western Conference play-in race in 2026-27, an outcome that could balance development with favorable lottery positioning.
Texas advocates warn proposed cuts to health, assistance programs could hurt vulnerable communities
The Texas Health and Human Services Commission proposed cuts to more than 20 client services programs. Dozens of Texas advocates testified at a legislative budget board hearing Thursday to ask state lawmakers to protect those programs.
Removal of 760,000 people from ACA marketplace could undermine US health system
Trump administration move weakens federal insurance programs – and some poor people will likely forego healthcare
David Bride: Small business investment could fuel resident interest
As mayor, I would focus on giving small businesses practical support. That means connecting entrepreneurs with public funding, private investment, banks and community organizations.
DARPA wants to give the military something much better than GPS
GPS can be jammed. DARPA is making clocks that could keep military systems running without it and eventually enable completely new capabilities.
Pioneer of China NewCo model sued in US over trade secret misuse, double-dealing
A legal feud unfolding in New York is putting a spotlight on the work of a business development veteran who is credited for pioneering one of biopharma’s hottest dealmaking mechanism: the China “NewCo” model. In a lawsuit originally filed in New York state court and recently moved to federal court, China’s Lepu Medical Technology has alleged that biopharma business development consultant Su Zhang, who was hired to help shop its GLP-1 weight-loss candidates to Western partners, engaged in corporate double-dealing and trade secret leaks. According to the complaint, while acting as Lepu’s primary dealmaking liaison for a group of obesity and metabolic disease drug candidates, Zhang was secretly double-dipping as the acting chief business officer for a direct competitor, BrightGene Pharmaceutical. “She never adequately disclosed the role, never sought Lepu’s consent, and never proposed any safeguard,” Lepu alleged in its complaint, which was filed in July after Zhang’s consulting firm, CoDevCo, sought certain transaction-based success fees from its angry customer through an arbitration process in Singapore. Lepu, the parent company of Lepu Biopharma, has asked Zhang to pay back its $500,000 retainer and disgorge all benefits she received during the alleged breaches of fiduciary duty, plus other damages and relief. The company has also requested the court grant injunctions to protect Lepu’s trade secrets. The ill-fated partnership officially kicked off in December 2024, when Lepu tapped CoDevCo as its “exclusive business development mechanism” to identify collaborators for the company’s drug candidates. According to Lepu’s complaint, Zhang personally negotiated and signed the agreement as managing director for CoDevCo, which used her home address. Before the Lepu deal, Zhang made a name following a short stint as the global head of business development for Hengrui Pharmaceuticals. It was during her tenure that Hengrui signed a landmark deal granting exclusive rights for a portfolio of GLP-1 assets to Hercules, which was at that time newly established by a group of private equity and venture capital firms. In addition to the regular upfront and milestone payments, Hengrui also gained an equity stake in Hercules, which later became Kailera Therapeutics. The Hengrui-Hercules deal opened a new paradigm, where a Chinese biopharma company spins off certain early-stage assets to investors for further development through the creation of a new company abroad. The “NewCo” model quickly came into vogue as it allows Western investors to access high-potential assets originating from China at an early stage while giving the Chinese licensors an opportunity to reap long-term benefits through equity stakes in the new firms. The NewCo model proved its value when Kailera staged a record-breaking $625 million IPO on Nasdaq this April, merely two years into the Hengrui deal. Related Kailera CEO 'knew we were in a good spot' before obesity biotech's record-breaking $625M IPO On her LinkedIn page, Zhang described her work at Hengrui as “[b]uilding team and capability from the ground up,” forming NewCo and major pharma partnerships worth billions of dollars. Lepu clearly wanted that kind of track record to help boost its own cardiometabolic portfolio, which includes a range of assets for obesity, Type 2 diabetes, fatty liver disease and muscle preservation during weight loss treatment. “Lepu’s pipeline is very valuable, but only if Lepu could secure the right international partner to expand into the overseas market during the available commercial window,” the company argued in its complaint. The Chinese biotech said it had little knowledge of U.S. laws, customs or business practices in the business development field, and therefore “needed to rely entirely” on the expertise of Zhang and her team as the firm’s first engagement of a U.S.-based BD consultant. “Zhang’s dominating influence on the business development strategy is further evidenced by the fact that she personally controlled the business-development communications on behalf of Lepu with potential partners,” Lepu said in its complaint. After entering the deal, Zhang introduced Lepu to her four associates. According to Lepu’s version of events, all of them were allegedly employed at different time points to perform similar jobs at other Chinese companies that Lepu described as its competitors, while having access to Lepu’s confidential information. As such, Lepu described Zhang’s team as “a roster of individuals whose primary professional loyalty, by virtue of their concurrent full-time employment, ran to Lepu’s competitors.” As well as the specific examples set out in the case, a look at Lepu’s deals over the period suggests Zhang may have been involved in at least one transaction. During their partnership, Lepu, through its subsidiary Shanghai Minwei Biotechnology, also out-licensed its GLP-1/GIP/FGF21 agonist MWN105 to a NewCo called Sidera Bio in the fall of 2025. The deal included an upfront and near-term payment of $35 million, up to $1.01 billion in milestones, and a 9.99% stake in the Danish startup. It seems likely that Zhang facilitated the Minwei deal given that Lepu is on record as having used CoDevCo as its “exclusive business development mechanism.” The big shock for Lepu came in the form of a news article on June 25, 2025. The article, reporting on phase 2 data for BrightGene’s GLP-1/GIP receptor agonist BGM0504, identified Zhang as acting chief business officer of the Lepu rival. Blindsided by her association with BrightGene, Lepu confronted Zhang in July 2025. “Lepu was given assurances that there was nothing to be concerned about and told that Zhang would explain the matter to Lepu,” Lepu alleged in its complaint. “Zhang never did.” Lepu claimed that Zhang had the motive and opportunity to steer potential prospective partners toward BrightGene or other competitors. Later, in February 2026, one of Zhang’s associates joined BrightGene as the vice president for global business development, according to the complaint. Around the same time, Lepu sent written demand letters asking Zhang to account for her BrightGene role, identify what confidential data were shared with the rival firm, and provide any conflict-of-interest or firewall policies during the engagement. According to Lepu, neither CoDevCo nor Zhang answered the questions in their responses. Related Novo vs. KBP: How a $1.3B deal turned into a fraud accusation and an international legal fight In a motion to dismiss filed with the U.S. District Court in the Eastern District of New York on Sept. 4, Zhang’s legal team argued that Lepu’s agreement was signed with CoDevCo, and that an employee of the contractor does not owe fiduciary duties to the client. In its complaint, Lepu said: “That CoDevCo was the contracting entity does not insulate Zhang from personal liability for duties she personally undertook and personally breached.” Taking the argument one step further, the defending party argued that the consulting agreement “does not create a fiduciary relationship even between CoDevCo and Lepu; instead, it identifies CoDevCo as an independent contractor retained to market Lepu’s business to potential western partners.” Although CoDevCo was Lepu’s exclusive business-development contractor, there were no terms stipulating that the consulting firm should serve only Lepu, Zhang’s lawyer noted. As to Lepu’s claims that Zhang misappropriated trade secrets, the defendant argued that Lepu authorized the use of the information so Zhang’s team could perform their service per the agreement. In a rebuttal filed on Sept. 11, Lepu’s lawyer set out why they believe the Chinese biotech satisfied New York law’s misappropriation definition by alleging that the defendant used a trade secret “in breach of a duty or through improper means.” As an alternative to dismissing the suit, the defendant suggested the action should be stayed pending outcomes from the arbitration of a separate case in Singapore. While NewCo pioneer Zhang is defending her business arrangements, momentum behind the NewCo trend has continued unabated into 2026. Through August, Chinese biotech assets have spurred 15 NewCo deals this year, according to local trade publication PharmaDJ.
Oklahoma’s Turnover Woes Could Doom Their SEC Run
Oklahoma's -4 turnover margin and weak rushing game are major red flags against Georgia. Here is why the Sooners are in serious trouble this weekend.
DNA database of UK dogs could help police collar criminals
Experts working on database that could identify particular breeds involved in crimes, or rule out canine suspects
CRISPR could help doctors attack blood cancer without destroying healthy cells
Researchers used CRISPR to remove CD33 from donor stem cells, potentially giving doctors a way to attack aggressive blood cancers without destroying the healthy cells patients need after a transplant. In a 30-patient trial, the edited cells successfully took hold and appeared to shield blood cells from a CD33-targeted cancer treatment.
Earth is tearing apart beneath the Pacific Northwest
Scientists have captured a subduction zone off Vancouver Island in the process of tearing itself apart, revealing that these massive tectonic systems may die piece by piece rather than all at once. The discovery could help explain ancient plate fragments, volcanic activity, and how hidden breaks beneath Cascadia may influence future earthquakes.
'Disgraceful' - Chris Sutton Makes Worrying Celtic Claim
Chris Sutton has made a Celtic claim that could leave the fans worried about the future.
Hung parliament: who could form a coalition after the next general election?
A ‘mega poll’ from YouGov suggests parties could be scrambling to forge an alliance
Can the Left Make America Fun Again?
Hi friends, I’ve got a piece in The New York Times today about how collective joy — participatory, youthful, anti-corporate — can defeat Trumpism and transform our lives. The basic argument is that politics used to be embedded in communal life: dances, sports leagues, union halls. As that infrastructure disappeared — and more of everyday life was atomized and privatized — politics became something broadcast at people rather than something they did together. NYC-DSA and Zohran provide another model, where socials and face-to-face organizing are tied to a fight vs the corporations that fenced off so much of the good life. Rebuilding that kind of collective fun, I argue, could help bring young people back into politics and, by redistributing America’s wealth, make everyday life more joyful. I would super appreciate it if you’d read the piece, share it, or post comments on it. Thank you! p.s. FYI, Opinion writers don’t get any say over their headlines! More Take action to support the fight of licensed deck officers at Alaska Tanker Company and Overseas Shipholding Group to win a first union contract. This is one of the most important, and underreported, unionization campaigns in America: these workers have a huge amount of power over domestic energy distribution and maritime supply chains, and they’re still without a contract two years after having voted overwhelmingly to unionize. Please sign the public petition here, and if you’re an academic you can sign this support letter.
Smith takes helm of Des Moines schools
A national search could have been launched by the Des Moines school board in its search for a new superintendent. Instead, the board turned to Matt Smith, an education leader with 16 years of experience in the district who brings a deep understanding of its challenges and a plan for its future. The Sept. 15…
Trump picked a fight with the media... and lost
Jonathan Freedland speaks to the Guardian’s Shrai Popat about why Trump seems weaker these days, and why it could be dangerous to underestimate him
Two questions the Wisconsin Badgers must answer vs. Penn State
The Wisconsin Badgers' season could take an incredible turn if they're able to defeat Penn State in Week 4.
Wall St Week Ahead Jobs report, inflation data to test US rate path, economic strength
Investors will sift through reports on employment and inflation in the coming week to assess chances of a sharper trajectory of interest rate hikes, which could undermine the US stock market's rally.
Texas advocates warn proposed cuts to health, assistance programs could hurt vulnerable communities
The Texas Health and Human Services Commission proposed cuts to more than 20 client services programs. Dozens of Texas advocates testified at a legislative budget board hearing Thursday to ask state lawmakers to protect those programs.
Virginia health committee considers mandating licensed nurses in every school
Virginia schools could be required to have a licensed nurse in every building starting in 2028, under a legislative proposal introduced Wednesday. The measure is designed to close healthcare gaps by placing experts in schools to manage complex medical conditions. Virginia permits school divisions to employ nurses, but state law doesn’t require it. About 8% […]
Pirates break single season strikeout record
The Bucs could have been better on the mound. And they were already pretty good.
Some dementia patients grow lucid near the end. Scientists hope it’s a clue.
Accounts raise tantalizing questions about what happens inside a brain afflicted by dementia and whether cognitive abilities could possibly be restored.
There’s a central place to donate to help Walhalla businesses destroyed in massive downtown fire
WALHALLA — Even as the rubble still smoldered in downtown Walhalla, the community shifted from shock over the businesses destroyed in a massive blaze to asking how they could help them recover. Now, t...
Why Germany Is Building an Ark for U.S. Climate Data
As researchers around the world begin work on the next U.N. climate assessment, fears are growing that the Trump administration could meddle with critical U.S. climate data.
Democrats weigh how to handle data center vote that could benefit a GOP foe
“They say they’re for more affordability,” embattled GOP Sen. Jon Husted said. “This is a chance for everybody to prove it.”
Who on Earth Could Start Game 162 for the Astros?
There are three games remaining in the 2026 regular season, and somehow the Astros control their own destiny in the American League West. The Astros have won two of three games this week despite not having a starting pitcher complete three innings. Hunter Brown will start Friday’s game in West Sacramento, with Hayden Wesneski likely […]
Utah Jazz Could See Major Player Swings as Expectations Rise
As the franchise pivots from development to winning, shifting stakes will test locker room veterans and rising stars alike, forcing critical adjustments in performance and nightly availability.
Future of Marketing Briefing: Imagining the ad business hiding inside Meta’s Muse
Meta built its $243 billion ads business on human attention. Agents could be next in line.
Thai court case risks election rerun and renewed political turmoil
An adverse ruling could force Thailand back to the polls within months, ending a period of unusual political stability.
Snakes Sweep and Still Alive: Dbacks 12, Rockies 8
The Arizona Diamondbacks stayed alive this afternoon as they were able to complete the 3-game sweep at Coors Field. This marks the first time since 2018 that the Dbacks have been able to complete a sweep at Coors, and it could not have come at a better time. The story of the game was the […]
Not just physics: Quantum to make business case at Chattanooga conference
EPB knows most businesses don't have a clear idea of how quantum technology could be useful to them. That's why the Chattanooga utility is hosting its inaugural "Quantum in Business" conference.
Agents involved in Mar-a-Lago search ask Judge Aileen Cannon whether gag order blocks testimony
FBI agents who probed Donald Trump’s handling of classified documents at his Mar-a-Lago home asked Judge Aileen Cannon on Thursday whether they could testify before a grand jury — or even consult their lawyers — as part of an investigation into whether former government officials conspired against the president.
Reducing the $2T federal deficit could lower inflation, interest rates for Americans: CRFB
Curbing the federal government's roughly $2 trillion budget deficit could lower inflation and current interest rates for households, a CRFB report finds.
Flutter Entertainment Falls as Guidance Cuts and a Recent Downgrade Weigh on Sentiment
Flutter Entertainment (FLUT) is down 4.4% today. Here is some analysis on what might have caused this price movement.Analysis: The most likely driver is continuing fallout from Flutter’s lowered 2026 outlook and a recent analyst downgrade that highlighted repeated guidance cuts and a slower-than-expected FanDuel sportsbook recovery. This could also reflect investor concern that heavier spending to defend market share may keep profits under pressu
Don’t Be Fooled: GOP Scuffle Over NIH Grants Doesn’t Mean Science Has Prevailed
Trump has backed down for now in his new bid to control research grants, but his tune could change after the midterms.
Politics Friday: How would having a woman as governor changes Capitol issue set?
Friday at noon, Minnesota is on the verge of joining the solid majority of states to have a woman as governor. We discuss what impact that could have on issue debates. Also, a look at the polling.
Panthers may soon get a much-needed return at RB
The Panthers could be getting back some much-needed help in their RB room pretty soon.
Sabres defenseman Mattias Samuelsson is listed as week to week
Buffalo could be down another blue liner with Olen Zellweger placed in the concussion protocol
Scientists sound alarm over new endangered species rules
Scientists and environmental advocates say Trump administration changes could put species like the North Atlantic right whale in harm’s way.
Mets Could Get Series Sweep While Ruining Rangers Season
Thomas Sorber Is Thunder's Forgotten First-Round Wild Card
Hidden behind injuries and draft-day hype, the physical Georgetown product offers a bruising interior presence and elite wingspan that could redefine the Thunder’s versatile frontcourt rotation.
NBA dark-horse contenders? Raptors, Warriors among teams that could make unexpected run
Should Raiders consider trading for Marvin Harrison Jr?
Former 1st round pick could use a change of scenery
Trump officials end review of how arch could harm historic sites
A required consultation process with local preservationists is being terminated, a Trump appointee said Thursday.
Probable Italy vs. Belgium line-ups and latest injury news
Italy tested Moise Kean and Francesco Pio Esposito together for the Nations League clash, while Belgium are without injured Leandro Trossard, but could start Napoli’s Kevin De Bruyne.It kicks off at...
Semaglutide is improving the heart health of millions—but how? Experts are stumped
“Our analyses could not fully ascribe the effects of semaglutide on cardiovascular disease to known risk factors with any certainty,” one researcher said after exploring years of data. "These results suggest that semaglutide should be considered as a cardiovascular disease reduction drug and not just as a weight loss drug,"
Eagles vs. Bears: 5 sneaky threats on Chicago's roster
The Eagles visit Soldier Field looking to keep rolling, but these five Bears could make Monday night's game much more difficult
Why Astros placed Cristian Javier on IL before MLB postseason
This could be a significant loss for the Astros.
The story behind Princess Diana's infamous revenge dress. And why she almost didn't wear it.
One of the most recognizable dresses in modern history is going up for auction and could fetch an eye-watering price. Why Diana's revenge dress is so coveted goes far beyond a fashion story.
‘The Three B’s’ Combined XI
Everyone has been talking about Brighton, Brentford and Bournemouth, largely due to their consistent ability to punch above their perceived weight. But what is the best eleven that could be fielded using only players from each club?
Starfield 2 will likely never happen because the first wasn’t ‘anywhere near successful enough’, former dev says
A sequel could have been much closer to the original vision…
How Snail Shells Could Help Scientists Track Storms From Prehistoric Times
Researchers linked growth spurts in a snail’s shell to 2 cyclones, suggesting shells could help uncover ancient storm tracks.
The same AI-chatbot could validate opposing political views. Could that deepen divisions?
A study shows chatbots mirror users' politics, part of a broader tendency known as AI sycophancy. Researchers fear this could deepen polarization.
The same AI-chatbot could validate opposing political views. Could that deepen divisions?
A study shows chatbots mirror users' politics, part of a broader tendency known as AI sycophancy. Researchers fear this could deepen polarization.
Farquhar hints 2027 could be his final chapter in sport
Ryan Farquhar hints that 2027 could be the final chapter for him in the sport - as the road racing legend reflects on crashes and family sacrifices on the BBC Bikes Podcast.
Roma interested in Kvernadze and Bakola for January
The right-footed left winger Roma has been seeking since Gasperini’s arrival could be just 90 kilometers away. After seeing a long list of targets fall through, from Summerville to Leweling, the Gia...
Control Resonant gets tough, but gives you the tools to deal with it
Thanks to assist mode, I could set my own challenge.
When what you see doesn’t make sense, your brain does something remarkable
The brain may have a built-in way to quickly settle disagreements between regions processing the same scene. Researchers found that matching signals between two visual areas lasted longer, while conflicting signals rapidly faded away. This “consensus building” mechanism could help explain how the brain turns many specialized inputs into one unified view of the world.
Distant time crystals can somehow fall into the same rhythm
Researchers have shown that multiple time crystals inside a semiconductor can synchronize their oscillations, much like pendulum clocks gradually falling into the same rhythm. The coupling is carried by spin-polarized electrons, allowing time crystals separated by up to 40 micrometers to lock to a common frequency. The discovery reveals surprisingly long-range connections between these exotic spin systems and could help researchers develop future spin-based devices.
Is metascience being co-opted?
In July, the White House released a report that argued academia is deeply dysfunctional and in need of radical reform.Science: A New Golden Age sets out a litany of problems many academics will recognise: interminable waits for grants; short-term funding rather than support for longer, more ambitious projects; ballooning administrative requirements; pressure to publish, and many more. “The scientific machine is getting bogged down,” it says. At least on the face of it, Science: A New Golden Age is a triumph for the metascience movement, a loose-knit, global group of academics, philanthropists and think tankers that want far more testing and experimentation in how we fund public research and innovation. The report tells US research funders to set up internal metascience units to do just this. But it has also set alarm bells ringing that metascience is being conveniently deployed to help justify the defunding of US universities, which US vice president JD Vance has openly labelled “the enemy.” “Just because you have an issue with your plumbing in your house doesn't mean you light the entire house on fire and burn it to the ground,” said Colette Delawalla, chief executive of Stand Up for Science, a group campaigning against what it says are attacks on scientists by the Trump administration. No one is arguing that academia doesn’t need reform, but there’s debate over how far and how fast the system should be shaken up. Does public R&D need slow and steady evidence-based adjustment, or radical new experiments?One of the key arguments in Science: A New Golden Age is that there’s not enough funding for what it calls “mid-level” science: engineering-heavy projects that require tens of millions of dollars, involve ten to a hundred people, and last around five years. Such a project might develop a brain-computer interface for people with Alzheimer's disease, for example. As such, the US National Science Foundation (NSF) has already announced $1.5 billion to set up so-called X-Labs, effectively new research organisations to pursue breakthroughs in areas such as quantum sensing and new scientific instruments. Funding divertedBut there’s a catch: this money has squeezed NSF budgets for more traditional, fundamental research grants, Science reported in June, likely meaning less cash for university-based scientists. Science: A New Golden Age also makes various swipes at universities, accusing them of extracting overheads from scientists to fund administrative bloat. “We have become dependent on a narrow set of legacy institutions,” it says. The report doesn’t mention it, but the US government is simultaneously seeking greater powers over federal funding, which would allow political appointees at funding agencies to screen or cancel research grants mid-project. The White House is also seeking to slash the NSF’s budget by more than half in 2027, although similar cuts proposed for 2026 were blocked by Congress. Convenient hookThis has worried some that the metascience agenda could be misused as a kind of smokescreen to further weaken universities. James Wilsdon, executive director of the Research on Research Institute at University College London, said that the report contains lots of “interesting ideas” and agrees that in places, academia is a “pretty broken system.” But the risk is that metascience is being deployed as a “convenient hook” to support cuts and a “political land grab” to transfer grant power from scientists to political appointees in US funding agencies.So far, the metascience agenda hasn’t been seized on by radical right parties in Europe. But Wilsdon worries it will cross the Atlantic, politicising research reform efforts and making them more difficult to carry out. The report is already making some in Europe sceptical of the entire idea. “The system is not without flaws, but the metascience discussion is not likely to improve the system but rather to generate munition to undermine it,” said Claes de Vreese, a professor of AI and society at the University of Amsterdam. Peter Thiel protégéOfficially, Science: A New Golden Age has just one named author: Michael Kratsios, the director of the Office of Science and Technology Policy and a former chief of staff to Silicon Valley mogul Peter Thiel. He also served as chief financial officer of Thiel’s Clarium Capital Management. Since the 1990s, Thiel has criticised US universities for moving away from teaching what he views as the classic works of western civilisation, and drifting towards “anti-Western zealotry.” And since 2011, he has offered two-year fellowships of $250,000 to young people to skip or drop out of university, and instead start companies or pursue scientific research. “College can be good for learning about what’s been done before, but it can also discourage you from doing something new,” according to the Thiel Fellowships website. In other areas, the Trump administration has promoted academics with a longstanding interest in metascience. For example, the head of the National Institutes of Health, Jay Bhattacharya, in 2020 co-authored a study arguing the funder backs overly conservative proposals, although he achieved wider prominence as a critic of pandemic lockdowns. Careless talk costs fundingEven before the Trump administration embraced the metascience agenda, some metascientists privately wondered whether they should be careful not to overstate dysfunctions in academia, in case this gets used as ammunition against universities. But others think being cautious with criticism is pointless. After all, last year, the Trump administration sought to cut funding from US universities on an entirely different premise: supposed antisemitism on campus. “I don't think these governments need a technical metascientific excuse to attack the universities, they will want to do so anyway,” said Will Stone, a researcher at Science Works, a new think tank advocating for a “metascience revolution” in the UK. “I think researchers should report what they find, even when the findings may be used to advance policies they disagree with,” echoed Russell Funk, a researcher at the University of Minnesota, who in 2023 co-authored a highly influential paper that argued scientific papers were becoming less disruptive over time. No justificationThat said, Funk thinks that metascientific research certainly doesn’t justify a weakening of universities. Instead, scientists need “time, resources and stability to pursue unfamiliar ideas,” he said. “Taking away those conditions works against the very goal the reforms are supposed to achieve.”The Institute for Progress, a Washington DC-based innovation policy think tank that has championed X-Labs and metascience units, also says that reforms should complement, not supplant, universities. “Unpredictable, unreliable, and reduced federal funding to researchers is destabilising to the very foundations of research and development and is bad,” said Jenn Gustetic, the institute’s director of metascience and R&D policy.Evolution or revolution?This points to a much bigger divide in the metascience community: how far and how fast should public R&D be shaken up? Does it need evolution or revolution? For example, Science: A New Golden Age says the science system relies too heavily on traditional “workhorse” project grants, the type that pay out around $250,000 a year to fund “hypothesis-driven science by small teams on tractable questions.” However, in criticising project grants, the report “decisively picks one side of a debate that is far from settled,” David Hilmer Rex, a metascientist based in Denmark, has written. In June, Pierre Azoulay, a metascientist at the Massachusetts Institute of Technology, defended project grants, saying that the alternative of X-Labs “merits scepticism.”A-B testingOne challenge in metascience is that it’s easier to generate evidence for some types of change than others. Most straightforwardly, research funders can run A-B tests on different ways of awarding money. For example, Germany’s Volkswagen Foundation recently trialled distributed peer review, where applicants rate each other’s proposals, and measured its results against traditional review panels. Distributed peer review made quicker decisions, although awarded money to largely different ideas. However, much of the focus of the metascience movement has been on founding fast-moving and free-acting new research organisations and funders, in contrast to the alleged stodginess of mainstream academia or public innovation grants. A culture of speed and freedom are the animating principles behind Germany’s Sprind or the UK’s Advanced Research and Invention Agency (Aria).Related articlesViewpoint: it's time to experiment with how Europe funds science European researchers sound the alarm that Trump rule changes will hit cooperationHowever, while it’s possible to closely study previously successful bodies, such as the US Defense Advanced Research Projects Agency (Darpa), for historical clues to their secret sauce, it’s impossible to guarantee in advance that the likes of Sprind or Aria will actually work as hoped. But advocates of new organisations say this inherent uncertainly shouldn’t stop us trying. “If we wait for definitive proof that something will work before we try it, I don't know where your proof is coming from,” said Stone. Trade-offsUp until now, experiments in metascience haven’t generally come with hard trade-offs over money. In the US, new ideas such as focused research organisations have often been funded by billionaire philanthropists. In Europe, new innovation agencies such as Sprind and Aria, or the Netherland’s new National Agency for Disruptive Innovation, haven’t needed explicit cuts elsewhere in the research system. But with the $1.5 billion establishment of X-Labs by the NSF, the trade-offs are becoming clearer. Some metascientists privately wonder whether a smaller pilot would have been more appropriate, given that the idea is untested. The Institute for Progress counters that the $1.5 billion X-Labs budget is spread out over a decade, so will account for less than 2% of the NSF’s annual budget. “It’s important to remember that [Darpa] was once an institutional experiment as well. Now it’s one of the most cited innovative funding models in the world,” said Gustetic.As for Europe?The US isn’t the only country placing metascience at the heart of its research strategy. Science: A New Golden Age looks admiringly at the UK, which in 2024 set up a Metascience Unit to scrutinise how it funds research. In Brussels, it’s more of a mixed picture. In 2018, the EU set up the European Innovation Council to funnel grants and equity to start-ups, although it’s sometimes criticised for awarding money too slowly. Recently, the council has started experimenting with challenges, where teams of inventors compete to overcome a technological challenge. The European Commission also wants to experiment with partially randomising grant winners, to cut down on bureaucracy. However, the Commission’s own advisers have said the EU’s own research schemes are too conventional. They want the Commission to establish a new dedicated unit to scrutinise and experiment with funding. But there’s no sign of a such unit emerging in Brussels’ plans for the next Horizon Europe programme, which from 2028 is set to distribute more than €160 billion over seven years. Sam Bogerd, director of breakthrough innovation at the Brussels-based Arq Foundation, an AI-focused think tank that also looks at metascience, says that Europe might have the opposite problem to the US: universities and basic research funding are still reasonably well supported, but there’s not enough experimentation. “We're not taking a close enough look at where this money can achieve the most, and I am worried that the good ideas around metascience will be tainted politically by their association with the Trump administration,” he said. He’s still lobbying for the Commission to set up an experimental unit. But in the meantime, the Arq Foundation plans to do its own research, and is currently hiring two metascience researchers to run the rule over how Brussels spends research funding.
Scientists thought they knew how this 70-year-old leukemia drug worked
A 70-year-old leukemia drug is still revealing new secrets. Researchers found that removing a protein called NUDT5 protected cells from the drug, even though simply blocking the protein had little effect. The unexpected result points to a hidden cellular role that could help explain why people respond differently to certain leukemia treatments.