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Guided search helps Kentuckians navigate treatment, mental health and recovery resources
A new guided search feature from FindHelpNow.org makes it easier for Kentuckians to find substance use disorder treatment, mental health care and recovery resources that fit their needs.
Pfizer makes ‘business decision’ to end phase 2 trial of autoimmune drug as program’s future uncertain
Pfizer has called time on a phase 2 trial of its CXCR5 antibody in an autoimmune blood disorder, with the company tight-lipped on whether this marks the end of the road for the asset. The Big Pharma had been evaluating the therapy, dubbed PF-06835375, in a phase 2 study of 61 patients with primary immune thrombocytopenia (ITP) that kicked off in 2022, according to the federal trials register. However, Pfizer confirmed to Fierce on Monday that this study had been terminated “due to a business decision.” “The decision to terminate the trial was not based on any safety concerns,” a spokesperson pointed out. At time of publication, PF-06835375 remained listed on Pfizer’s website for both ITP and lupus. A phase 1 study in lupus wrapped up in 2022, according to the trials database. ITP is an autoimmune disorder characterized by a low platelet count. Novartis was at one point evaluating its B-cell-depleting antibody ianalumab—recently approved as Fabhalta to treat immunoglobulin A nephropathy—as a potential treatment ITP. But the therapy struggled to demonstrate a benefit in the clinic for this indication. When contacted by Fierce, Pfizer wouldn’t confirm whether all work on PF-06835375 has been halted, and whether the company has any other plans to explore C-X-C chemokine receptor type 5 (CXCR5) as a mechanism. CXCR5 is found in blood cancers such as diffuse large B-cell lymphoma and mantle cell lymphoma chemokine receptor. However, there is little expression in normal tissue, which has led some drug developers to explore its potential. Vincerx Pharma had at one point been planning to take an anti-CXCR5 ADC into the clinic to treat B-cell malignancies, but that ambition was scrapped due to cash constraints. Where Big Pharma is placing its bets is one of the hot topics being discussed at Fierce Biotech's high-impact event in London next month. Find out more information and register by clicking on the banner below: [ ](https://qtxasset.com/quartz/qcloud5/media/image/where_big_pharma_is_placing_its_bets.png?VersionId=B8JrRbJ.pFUSK1pJgjeWHLGm_18RdLAy)
GLP-1 drugs may protect kidney health in people with bipolar disorder
Mayo Clinic researchers found that GLP-1 receptor agonists, medications widely used for diabetes and weight management, were associated with a lower risk of dialysis or kidney transplantation in adults with bipolar disorder and chronic kidney disease.
James Maddison marks first Tottenham start in nearly 18 months with stunning goal in first Premier League win of season
Tottenham playmaker struck opener in 3-1 win over Coventry which moved side off foot of Premier League; the 29-year-old was making his first start following torrid long lay-off after suffering an ACL injury
Rangers Find Their Offensive Rhythm In Win Over Ducks
The New York Rangers’ offense came alive on Monday night at Madison Square Garden, en route to a decisive 5-2 victory over the Anaheim Ducks.
UFC 333 Embedded, Episode 1: 'I just take their zeros'
The first episode of UFC 333 Embedded was released on Monday.
GLP-1 Drugs and Mental Health: Effects on Depression and Anxiety
GLP-1 receptor agonists affect pathways involved in mood, appetite, and reward, prompting research into their potential benefits for depression, substance use disorders, and binge eating. Psychiatric treatment benefits remain unproven, while conflicting observational findings and reassuring trial evidence require careful interpretation.
After years of backlash, Apu returns to 'The Simpsons' with a South Asian voice
The Halloween-themed episodes of “The Simpsons” have always been a treat of spooky stand-alone storylines | KNX News 1070 AM
Bears Receive New Trade Take on Colts DT DeForest Buckner
Harrison Graham of Chat Sports believe the Bears should look to make a trade for Colts defensive tackle DeForest Buckner. The post Bears Receive New Trade Take on Colts DT DeForest Buckner appeared first on HEAVY.
Reid Defends Kicker Who’s Still Taking Away Points
Kansas City Chiefs kicker Harrison Butker missed two kicks on Sunday, but Andy Reid doesn't sound concerned.
Scientists discover a surprising link between vitamin C and cancer survival
A surprising clinical trial suggests that taking vitamin C daily could improve survival in people with precancerous blood disorders and early-stage blood cancers. Patients receiving the supplement had fewer adverse events and showed a promising survival advantage, raising hopes that a common vitamin could help protect against leukemia-related complications.
Entertainment Look-A-Head: ‘Cyberpunk: Edgerunners 2,’ ‘Call of Duty: Modern Warfare 4,’ ‘Clayface’
From Oct. 20-25, new games launch, movies hit the theaters and several series get new episodes.
MTSU group selected for prestigious Berkeley Lab learning opportunity
MURFREESBORO, Tenn. — Five students from Middle Tennessee State University will travel to California this November for an immersive “mini-semester” at Lawrence Berkeley National Laboratory, also known as Berkeley Lab. Nyah Bentley, Addison Berry, Tomy Chet, Sarah A. Holzmann, Gavin Liles and Gloria Silva will join groups from two other universities, Spelman College and the University of […]
Mental Health Monday: Resources for those in recovery
Chelsea Bly, Associate Director of Children’s Services at Valley Health, joined Holly Baratta to tell us about substance abuse disorder in West Virginia and the resources available to take the first steps towards recovery.
Joint Statement for the International Day of Political Prisoners on October 30
On the International Day of Political Prisoners, the October 30 Coalition and NED release a joint statement urging support for political prisoners and those championing their freedom.
How will the riots in France affect the country’s politics?
For weeks, people in France have been protesting over the cost of living and school conditions. But this weekend, many protests turned violent -- and now French officials have implemented a curfew to quell the violence. The country’s far-right is seizing the moment to make a case for their policies.This episode was produced by Sophia Paliza-Carre and Karen Zamora, with audio engineering by Damian Herring. Our director is Kathryn Fink.It was edited by Mallory Yu and Tinbete Ermyas.Our interim executive producer is Courtney Dorning.Support public media with NPR+ and enjoy perks for over 25 podcasts like this one. This show’s perks include bonus episodes and sponsor-free listening. Learn more at plus.npr.org.
You can still get into Macklemore’s sold-out Red Rocks Amphitheatre show for under $100
The Seattle rapper plays a sold-out show in Morrison on Oct. 22.
Trump Wades into Israeli Politics
Netanyahu is stumbling toward the finish line of this election cycle with Israel isolated internationally more than ever before, as major European partners have all but turned their backs on the Jewish state, and a majority of Americans view Israel negatively.
'Other Desert Cities' review: Julia Louis-Dreyfus debuts Broadway
A revival of Jon Robin Baitz's 'Other Desert Cities,' directed by John Benjamin Hickey, opens at Broadway's Hudson Theatre with a cast that includes Julia Louis-Dreyfus, Ed Harris and Allison Janney.
Folk duo Buffalo Traffic Jam adds Madison show to sold-out 'Pictures of You Tour'
MADISON (WKOW) — Buffalo Traffic Jam is bringing their sold-out "Pictures of You Tour" to The Sylvee on Feb. 21, 2027.
See your patient population more clearly with the UNOS SDOH Report
The UNOS Social Determinants of Health Report helps transplant programs better understand the social and economic factors affecting their patient populations through center-specific data and regional, peer and national comparisons. These insights can help programs identify trends, support quality improvement and advance more equitable access to transplantation.
Health and Human Services nurses win Public Health Award
Two Gunnison County Health and Human Services public health nurses, Shonna Gray and Amelia Meyer, were awarded the Exemplary Public Health Nurse Award at the recent Public Health in the Rockies …
'The Simpsons' shocks with return of Apu after controversy
Apu is back on "The Simpsons." In the animated series' latest episode, the character spoke for the first time in almost 10 years.
Toxic Algae Health Advisory in Effect for Pattison Lake
Thurston County Public Health & Social Services is reporting a toxic algae bloom in Pattison Lake.
Roberto De Zerbi Breaks Silence On Richarlison
Tottenham Hotspur head coach Roberto De Zerbi has insisted Richarlison’s future is no longer his ‘problem'
Worried About Your Teen? Check Their Dental Exam Results For A Window Into Their Well-Being
By Dennis Thompson HealthDay ReporterMONDAY, Oct. 19, 2026 (HealthDay News) — You can tell a lot about your teen from their oral health, says a new American Academy of Pediatrics (AAP) report. Many teenage health problems — eating disorders, smoking, drug use, sexually transmitted diseases — can be ...
Meatballs on hold: IKEA delays opening new Madison store until spring
The Swedish furniture and home decor company confirmed the updated plans for its second Wisconsin location in an email to the Cap Times.
The sport of online harassment
Non-consensually posted intimate images can devastate women – and beget male bonding.The burner accounts on X loosely grouped into the “burnerverse” started by bonding over college sports – but soon took a darker turn when some of them began trying to make salacious rumors or non-consensual intimate images of young women and their names go viral. Ej Dickson investigated the burnerverse for Wired, profiling one of these women who were doxxed – and found links between these burner accounts and college fraternities. But what makes misogyny such a potent tool for men’s bonding? And with laws against non-consensually distributed intimate images in all 50 states – how is it still happening at scale?To talk more about the culture that supports this kind of harassment and the structures that keep it in place, Brittany is joined by Ej Dickson, senior culture writer at wired, and Dr. Mary Anne Franks, professor at the George Washington University Law School and president of the Cyber Civil Rights Initiative.Support public media with NPR+ and enjoy perks for over 25 podcasts like this one. This show’s perks include sponsor-free listening. Learn more at plus.npr.org.
Farmworkers’ health matters: South Africa looks to alternatives for chemical pesticides
Insects like fall armyworm or mealybugs can decimate food and commercial crops; like their counterparts elsewhere in the world, South Africa’s small and large farmers alike use synthetic chemical pesticides to control these and other pests. But about 385 million cases of unintentional acute pesticide poisoning are reported worldwide each year, according to the Pesticide […]
10 Best Maine Registered Agent Services Of 2026
Discover the best registered agent services in Maine for 2026.
New Episode “The Science Fair Disaster” Inspires Children to Embrace Science, Creativity, and Learning from
— Keisha and Alexis’ Grand Adventures, an educational animated YouTube series for children ages 5–10, introduces its latest episode, “The Science Fair
MGPI to rebrand as Sempreon
Move represents the next chapter for Atchison, Kan.-based company.
Streaming’s Biggest Show Returns…and a Buzzy Genre Struggles
(Welcome to my weekly streaming ratings report, the single best guide to what’s popular in streaming TV and what isn’t. I’m the Entertainment Strategy Guy, a former streaming executive who now analyzes business strategy in the entertainment industry. If you were forwarded this email, please subscribe to get these insights each week.) Obviously, the big news of the week (if not month) is Netflix letting go of executive Bela Bajaria, their chief content officer. I’m going to cover this in my next “Most Important Story of the Week”, but I also have a data angle that I might publish before then. (Too much news this month, am I right?) But first, I have a bonus Streaming Ratings Report issue for you. Today’s article is a bit of a grab bag of topics I’ve wanted to write about, but couldn’t squeeze into the (already very long) Streaming Ratings Report issues. The NFL drives huge viewership numbers, so I’ve got a look at that. A whole bunch of TV shows returned to the traditional broadcast channels, and I have thoughts. And I have a quick look at adult animated shows, since a couple flopped earlier this month. Plus, the Emmys aired earlier this month, and we got some fun data bout how popular those nominated shows are and why I’m not optimistic about the show’s future. That’s a lot, so let’s dive right in. Subscribe Sports - Football Remains the King of Streaming Over the last two Streaming Ratings Reports, I sorta ignored the biggest “show” each week. (I was tempted to say “piece of content” but I know that word bugs folks.) In my database, I call these “specials”, and they sure are special. I speak of the king of American TV: football!!! Streaming football is back and, unlike some other sports, it routinely dominates all viewership. Probably the best way to show this is to update one of my favorite graphics, the “40 Million Hour Club”1 since football games have joined that club each week they’ve premiered: (Yep, that’s the data through 28-Sep, the first four weeks of the season. As a reminder, I take the average minute audience provided by Nielsen, factor out a percentage of linear TV viewers in home markets, and multiply the run time by the three-hour runtime.) Again, the numbers are huge. Let’s start with Netflix. They grabbed the rights to the bonus opening week NFL Kickoff game (which was on YouTube last year) and it put up 18.5 million viewers on average. That nets out to 47.4 million hours of estimated streaming hours. That’s good! Though, notably, it’s well below Christmas Day games from previous years. Compared to other streamers/broadcasters, that’s a bit of a mixed result. On one hand, Netflix’s 18.5 million average is about what YouTube claimed last year, though Nielsen used a bespoke methodology at that time, so I trust this viewership figure more. So that’s good. (The game also shifted from a Friday to a Thursday and that could have helped the viewership as well.) And Netflix continues to best Prime Video in total viewership—as you’ll see next—though Netflix has had much higher-profile (opening week and Christmas Day) games. NBC/Peacock’s opening game the night before averaged 25.1 million average viewers, which is just much bigger than Netflix (or Prime Video). That’s the big caveat to all streaming viewership records: even in success, they can’t compete with traditional linear TV. Previously, I called this my “hierarchy of viewership”, and the data keeps supporting that thesis. The downside for NBC is that this game’s viewership was down compared to previous years, though it may be a counting issue. Here’s a great chart from Sports Media Watch: Indeed, looking at all the opening week games across all windows, Netflix still lags the other primetime windows, but does well compared to the afternoon games: I saw a few folks make the case that streamers still lag traditional broadcasters in reach, and I’d add they really lag compared to “broadcast plus streaming” options like NBC/Peacock, ESPN/Disney+ and CBS/Paramount+. The best data I saw for this came from Samba TV, who charted reach through the 2025 season, and, wow. (Samba TV’s numbers are historically lower than Nielsen’s, so don’t compare their household figures to Nielsen’s hours, but use them as a proxy for the relative reach of the streamers.) The good news is Prime Video is NOT having a down year. Their opening Thursday Night Football game reached 18.6 million viewers (about what Netflix got), but that’s a high for Prime Video on Thursdays and the biggest Thursday night game since 2015. The TNF games the weeks of 21-Sep and 28-Sep continued this streak, getting 43.1 (16.8 million average viewers) and 42.5 total hours (16.6 million average viewers), which were both up from last year. Still, that continues the (typical) season slide: (For those new-to-streaming-football-numbers folks, the viewership declines for Thursday Night Football as the year goes along.) Overall, it appears as if Prime Video is now part of the “football habit”, be it for customers at home or out at places like bars and restaurants. And its viewership is slowly catching up to broadcast. One last chart shows this. Last season, Nielsen started adding out-of-home viewership to the charts, so I try not to do season-to-season comparisons as I did for the first few years. And while Nielsen added Big Data viewing this year, I’m going to compare the last two seasons. Here’s that chart, which shows the season-over-season gains: When it comes to streaming football, we have to keep a few seemingly contradictory thoughts in our head… First, streaming doesn’t come close to matching broadcast’s reach and, thus, viewership. Second, even with that gap, football is still the biggest “thing” on streaming. It’s very, very popular. Third, while some methodology changes have likely helped Prime Video’s numbers, their viewership does appear to be growing. Lastly, yeah, the NFL started the season off poorly, with week one dragging down the numbers in year-over-year comparisons. However—and again, methodology changes may have helped this—the viewership grew compared to previous seasons over the next couple of weeks. So football is still king. On streaming and off. Television - Adult Animation Continues to NOT Make the Streaming Charts In the last two reports, two adult-animated shows whiffed: Netflix’s animated comedy, Dang! Paramount+’s Sega-video-game-inspired fantasy/comedy, Golden Axe. Neither made the charts, but that’s usually the case for animated shows. I mean, here’s literally every animated show that’s made the Nielsen Original charts since the start of 2025: And one of those shows is G_abby’s Dollhouse_! A kids show! The problem with charts like this is that they don’t give you a sense of how many shows miss the charts. Netflix had at least eleven animated flops, including comedies like Big Mouth (a show everyone assumed was popular in the pre-Streaming Ratings Era), Long Story Short, Haunted Hotel, Mating Season, Strip Law, and Alley Cats, and action shows like Blood of Zeus, Castlevania: Nocturne, Devil May Cry, Splinter Cell: Deathwatch, and Tomb Raider: The Legend of Lara Croft. Prime Video had at least six animated misses, two in the same universe (Hazbin Hotel, Helluva Boss), three more comedies (#1 Happy Family USA, The Second Best Hospital in the Galaxy and Kevin) and an action show (The Mighty Nein). Disney+ had MCU and Star Wars animated misses (Eyes of Wakanda, Marvel Zombies, Star Wars: Visions, Star Wars: Maul – Shadow Lord, and Star Wars: Tales of the Underworld) but I can’t tell how many of those shows were geared towards adults. HBO Max had Harley Quinn and Hulu had Solar Opposites. None of these shows made the charts! That’s a lot of misses! If I remade the chart with all those misses, here’s how it would look: Listen, I know the counter arguments. First, it’s cheaper to produce animated shows than live action. Fair enough, but with viewership this low, even that cheaper price point starts to not matter. Second, just look at the acquired charts. Hit animated comedies can generate viewership for years! Shows like The Simpsons, South Park, Family Guy, and Bob’s Burgers do really, really well. Fair enough, but streaming has failed to recreate the dynamic that Fox has mastered so well. That’s a problem for streaming still. Television - Emmys! The annual Emmys broadcast was a few weeks ago, and I’ve got data on how the nominees performed on streaming, plus hot takes on this year’s viewership (and the big news about the broadcast’s, er, streamcast’s future). We’re just getting started with this issue, but the rest is for paid subscribers of the Entertainment Strategy Guy, so if you’d like to find out… The top Emmy-nominated shows… ...why I’m worried about the future of the Emmys telecast... ...the pros of broadcast television ...and the cons... ...please subscribe! We can only keep doing this great work with your support. Coming Soon! Next week, we’ve got a double issue (since the weeks of 21-Sep and 28-Sep were so light), but then I’ll be all caught up after a deluge of streaming ratings data from Nielsen in September. In the meantime, I’m going to try to take a look at Netflix’s stats to explain why Bela Bajaria is out. But even light weeks give me plenty to talk about. The Great British Baking Show returns to Netflix and Apple TV has a buzzy new star-studded comedy. And Netflix has a controversial-but-appears-to-be-popular new game show. Plus big films like Toy Story 5, Backrooms and The Breadwinner head to streaming. And is East of Eden a hit? After that, The Kardashians return to Hulu, Prime Video has a reboot of Carrie, and Netflix has a horror show, Below. Disclosure Day heads to Peacock, The Housemaid heads to HBO Max_,_ a new Ben Affleck film, Animals, lands on Netflix, and Apple TV has a new John Cena action film based on, checks notes, Hasbro’s Matchbox toys. Okay. Longterm, some interesting TV production news. HBO Max ordered How to Survive Without Me, starring Kaley Cuoco, Joshua Jackson, Ray Romano and Rita Wilson, for fifteen episodes! I love that some streamers (or, at least, HBO Max) are finally ordering TV shows with more than eight episodes. In less wise production news, Landman does not appear to be coming back this year, since it just started production. Frankly, I don’t love this (get your shows out on time) but Landman is so popular, I doubt it matters.
LIFE-HEALTH-GLP-1S-ALCOHOL-FILEPIC-DMT
A Philadelphia Veterans Affairs doctor is leading a national trial testing whether GLP-1 drugs could help patients with alcohol use disorder.
Learn Why The Bull Case For Madison Square Garden Entertainment Stock Could Change Following Revenue Jump
Madison Square Garden Entertainment reported revenue of US$1.1b, up 13% year on year, supported by the New York Knicks’ NBA Championship run and record sales for its Christmas Spectacular. The 30 day Harry Styles residency now under way at the Garden underscores how concentrated, high profile bookings can deepen event utilization across an already busy venue portfolio. We will look at how Madison Square Garden Entertainment’s investment narrative is affected by this 13% revenue jump and...
How to Watch Grimsburg Season 3, Episode 3
Grimsburg is back after a week off with Season 3, Episode 3, "Breaking Badly." Jon Hamm returns to Grimsburg as Detective Marvin Flute to solve the town's
California Politics 360 full episode | California, US government clash over voter rolls
The Trump administration sued California election officials this week. They asked a judge to block the state from counting mail-in ballots from people the federal government has identified as “likely” non-citizens until their status can be confirmed.
The 20 best “Bluey” episodes of all time
Even adults love the hit Australian animated series.
The 20 best ‘Bluey’ episodes of all time
From baby races and grumpy grannies to obstacle courses and sleepytime, these are our picks for the best episodes of ‘Bluey’ so far.
Readers respond: Coordination, not isolation, for Oregon State Hospital
Letters to the Editor can be submitted to letters@oregonian.com with full name and place of residence.
David Crowley says Black infant health is a priority; no response from Tom Tiffany
David Crowley, the Democratic candidate for governor, responded to a questionnaire from the Cap Times about Wisconsin’s ongoing Black infant mortality crisis. Tom Tiffany, the Republican nominee, d…
Allison Williams Says There Is ‘a Science’ to Buying a Kids’ Halloween Costume as a Parent (Exclusive)
The actress shares a 4-year-old son, Arlo, with husband Alexander Dreymon
Bob Ferguson’s board is telling him to let people out of prison. He keeps saying no
Ferguson has given little explanation as to why he has so often rejected the recommendations of his Clemency and Pardons Board.
New guided search tool helps Kentuckians navigate treatment, mental health and recovery resources
By Leah Dick University of Kentucky Finding the right support for substance use disorder treatment, mental health care, recovery housing or naloxone distribution can be an important step toward better…
'Dancing with the Stars' pro Val Chmerkovskiy pulled after Carrie Ann Inaba remark
"Dancing with the Stars" pro Val Chmerkovskiy will miss next week's episode after a controversial social media remark about Carrie Ann Inaba that seemed to reference Will Smith's Oscars slap.
Veterans Services Fair promotes mental health support
Shingleton said the former Army slogan “Army of One” was a perfect example of the isolation veterans can experience.
SCIENCE-DINOSAUR
In this illustration, the meat-eating dinosaur Invictibellatrix amberina feeds on a mammal while grasping another alongside other dinosaurs on the Isle of Wight, United Kingdom, in the Cretaceous Period around
Val Booted Next DWTS Episode, Jenna Dewan Dance With Alan
“The well-being of everyone who works on 'Dancing With the Stars' is non-negotiable. Val’s social media post was inappropriate and does not reflect the values or standards expected of anyone connected with the show. As a result, he will not participate in next week’s show," BBC Studios said in a statement.
The strange genius of Nathan Fielder, explained in 5 episodes
Nathan Fielder’s ‘You Can See Everything’ has everyone talking. But how do you even begin to explain his whole... thing? These five essential TV episodes are a good place to start.
Business Notes: Spanberger appoints Hampton Roads leaders to advisory council; $1.6M raised for St. Jude’s
View the latest business milestones and professional accolades in Hampton Roads.
Man gets 2 life sentences for killing 2, injuring 3 in Chester business shooting
A man was sentenced to two life terms in prison for killing two brothers and injuring three other people at a laundry business in Chester in 2024.
What to know about menopause and mental health
In honor of Menopause Awareness Month, mental health expert and physician's assistant Rebecca Barbee joins us to discuss how menopause can intensify emotional challenges for women living with mental illnesses including bipolar disorder.
Knicks’ Season Opener: 3 Things To Watch Against 76ers
In the New York Knicks' season opener, the team will begin their quest to defend the NBA title. There will be no easing into things over the Knicks' first 10 games. In particular, when they welcome the Philadelphia 76ers to Madison Square Garden on Tuesday, Oct. 20, they'll be facing a revamped opponent with plenty …
Appeals court blocks part of Arizona prison healthcare order
The 9th Circuit Court of Appeals, in the unsigned order, said that the state is raising "serious questions" about the ability of a federal judge to take over health care in a prison system.
Brain cells meant to protect us may be fueling cognitive decline
Scientists have uncovered a surprising cause of age-related cognitive decline involving brain cells previously thought to be entirely beneficial. As these cells become dysfunctional, they can produce abnormal amounts of myelin, disrupting nerve fibers and potentially contributing to worsening memory and thinking skills.
Rabies reports are rising in California. Experts can’t explain why
Rabies reports are up across the U.S., including in one greater Bay Area county where human exposures to rabid animals have tripled, prompting a local advisory to stay away from sick creatures.
Madison Square Garden Entertainment Corp. $MSGE Stock Bought by Assenagon Asset Management S.A.
Assenagon Asset Management S.A. grew its holdings in Madison Square Garden Entertainment Corp. (NYSE:MSGE - Free Report) by 42.4% in the 3rd quarter, according to its most recent disclosure with the Securities and Exchange Commission (SEC). The institutional investor owned 1,229,680 shares of the co
Prison healthcare takeover put on hold as Arizona’s appeal moves forward
Arizona prison healthcare receivership: An appeals court delays the takeover, keeping the state in control pending its appeal
Springville businesses fear festival losses amid SCE power shutoff
Southern California Edison power safety shutoffs left Springville businesses concerned about communication and potential losses.
Sean Combs transferred to new prison after perks report, head injury
Sean Combs was transferred on Friday to FCI Allenwood, a low-security prison in Pennsylvania, following allegations of special prison perks and a head injury at FCI Fort Dix in New Jersey.
Scientists discover how deep sleep builds muscle, burns fat, and boosts the brain
Scientists have discovered a surprising two-way relationship between sleep and growth hormone, revealing how the brain carefully balances physical recovery with wakefulness. The findings could help explain why poor sleep harms metabolism and brain health, potentially opening the door to new treatments for sleep and neurological disorders.
Politics Unusual: Governors debate discussion, ballet props
In this episode of Politics Unusual, FOX 5 NY’s political reporter Morgan McKay sits down with politics strategists to discuss the recent New York gubernatorial debate between Gov. Kathy Hochul and Republican nominee Bruce Blakeman. Also, a conversation with the executive director of Citizens Union about the five ballot propositions.
7+ Florida Politics Now: Discussing the upcoming midterm elections
On this episode, we’re discussing the upcoming midterm elections.
7+ Florida Politics Now: Discussing the upcoming midterm elections
On this episode, we’re discussing the upcoming midterm elections
Netflix Scrambles to Rewrite Its Narrative With Layoffs and a Sudden Firing
Despite strong revenues and profits, the streaming service cut 1,000 jobs and jettisoned its chief content officer. Drops in the stock price and viewer engagement are to blame.
Financial advisor advises to review health plans before cutting costs
Open enrollment is underway, and one financial advisor says there are specific places to cut costs and places not to.
Historic Torrance building to be transformed into community health clinic
L.A. County Supervisor Janice Hahn officially broke ground on the new Pathway Torrance Community Health & Wellness Center on Friday, Oct. 16.
Cin-Emma Extra! reviews ‘You Can See Everything’ documentary, talks incoming ‘Club Kid’
“You Can See Everything” documents the 34 days before Theranos co-founder Elizabeth Holmes is sent to prison.
Billy Joel can't drive or perform following brain disorder diagnosis
Billy Joel shared health updates following his 2025 brain disorder diagnosis, stating that he has to take “a series of tests” before being able to tour and drive again.
Indigenous Biz Con explores a renaissance in Tribal business, technology and entertainment
Indigenous Biz Con returned for its fifth year Oct. 11-13, bringing Indigenous leaders, entrepreneurs and community members to Milwaukee to explore a potential economic renaissance for Indian Country. The annual conference, held at Potawatomi Casino, featured discussions on the current state and
Indigenous Biz Con explores a renaissance in Tribal business, technology and entertainment
Indigenous Biz Con returned for its fifth year Oct. 11-13, bringing Indigenous leaders, entrepreneurs and community members to Milwaukee to explore a potential economic renaissance for Indian Country. The annual conference, held at Potawatomi Casino, featured discussions on the current state and
Sean 'Diddy' Combs transferred to Allenwood prison
Disgraced music producer Sean "Diddy" Combs, who was sentenced for prostitution-related crimes, has been transferred to a new US prison following media reports detailing an alleged brawl and special treatment
Sean ‘Diddy’ Combs transferred to new federal prison after medical emergency
Sean ‘Diddy’ Combs was moved from FCI Fort Dix in New Jersey to FCI Allenwood Low in Pennsylvania days after he reportedly suffered a head injury.
Health officials issue water quality advisory for Fort Walton Beach park
The advisory remains in effect until follow-up testing confirms bacteria levels have dropped back into acceptable safety ranges.
'Avatar: Seven Havens' episode 5 is chock-full of 'Last Airbender' Easter eggs
Plus, a treat for Korrasami fans!
Sean ‘Diddy’ Combs moved to new prison after reports of luxury lifestyle
The hip-hop mogul has been moved to a federal prison in Pennsylvania after reports that the he was living the high life and was injured in a fight at his New Jersey lockup, a source said
Jax from ‘Love Is Blind’ stands by comparing Stew to Mitt Romney after Kennedy comparisons
‘Love Is Blind’ stars Jax and Stew talk to EW about their awkward breakup — and whether he looks more like John F. Kennedy or Mitt Romney.
Billy Joel Shares Heartbreaking Health Update After Brain Disorder Surgery
The 'Piano Man' singer, 77, was forced to cancel his tour in 2025 due to normal pressure hydrocephalus.
Billy Joel Shares Heartbreaking Health Update After Brain Disorder Surgery
The 'Piano Man' singer, 77, was forced to cancel his tour in 2025 due to normal pressure hydrocephalus.
Sean 'Diddy' Combs moved to a new prison after reports of a luxury lifestyle behind bars
Sean “Diddy” Combs has been moved to a federal prison in Pennsylvania after reports that the hip-hop mogul was living the high life and was injured in a fight at his New Jersey lockup | WBBM Newsradio 780 AM & 105.9 FM
Can AI solve our mental health access problem?
Last week I asked you what worries you most about AI in health. It was close, but your top answer was “AI giving bad health advice.” Last week’s poll results: You’re in good company. This concern was top of mind at a conference I joined at Stanford last week, where researchers, clinicians, and people who build AI systems spent a day debating trust and safety in health AI. Stepping back, I’m also hearing your emerging concerns about AI’s impact on our well-being generally. I see this as a matter of public health, and we’ll take it in pieces as we learn together. Today we’ll focus on AI chatbots used for therapy for mental health. Early this month, Governor Newsom vetoed Senate Bill 903, California’s most ambitious attempt to regulate AI use for mental health. It’s at the center of active debate, and raises the questions patients, family members, citizens, and voters will face as AI moves deeper into health care. Let’s work through it. What is “AI-based therapy”? It’s really two things: purpose-built mental health apps designed to deliver structured support, and general chatbots like ChatGPT, Claude, and Gemini that people increasingly use for emotional support—even if they weren’t built for it. Spoiler alert: I don’t know whether the shift toward AI therapy is good or bad. The evidence isn’t there yet. But I do know it’s already happening, and I have some ideas about how we can roll it out with safety in mind. The therapy dilemma, in a nutshell Mental health challenges are common, and strain health and well-being across populations. Therapy (interactive dialogue with a trained, empathetic practitioner) helps many people heal. The demand for licensed therapists far exceeds the supply in California, and AI-based therapy can narrow that gap. AI-based therapy remains novel, unproven, and not well tested. Right off the bat, we can see we’re dealing with trade-offs here. Since the main driver of demand for therapy from a robot is lack of access to therapy from a human, we’ll start there. It’s too hard to find and afford a human therapist California is short roughly 55,000 licensed, non-prescribing therapists and counselors, about 40% of what we need. Psychiatrists, who rely on talk therapy as a complement to prescribed medications, are even more scarce. Eight counties have none, and density ranges from 1.7 per 100,000 residents in San Benito County, to 68.1 in Marin County. My wife is a psychiatrist in Marin, and even here access is tight. If it’s hard in the best-supplied county, imagine rural Sierra County, or the San Joaquin Valley. In 2024, more than half of Californians who tried to make a mental health appointment struggled to find a provider who took their insurance, compared with 14% for physical health care. When Senate staff posed as “secret shopper” patients and called 120 mental health providers in Medicare Advantage networks, they landed an appointment less than once for every five tries. Insurers pay behavioral health clinicians about 22% less than medical and surgical clinicians for comparable office visits. On top of that, billing denials and prior authorizations hit hardest at the solo and small practices common in mental health. Psychiatrists opt out of Medicare at the highest rate of any specialty. In many places, a cash practice for therapy fills quickly with patients paying $250 or more an hour, with no insurance paperwork at all. Families who can pay cash find providers more easily. Those who rely on insurance, including Medi-Cal enrollees, older adults, rural residents, and non-English speakers, compete for what’s left. So we can’t pretend the human system works, and we can’t blame people for turning to AI for support when they’re in distress. AI is filling the gap It’s estimated that roughly a quarter of AI users use it for mental health support. If you have internet, it’s available 24/7, it’s cheap, and it speaks your language. Uninsured adults are about twice as likely as insured adults to do it (30% vs. 14%). It feels anonymous in ways that may enable people to ask things they’re unsure or embarrassed about. The largely hidden, personal use makes it hard to study whether it’s actually helping people with their mental health issues, but researchers are trying. Does AI therapy work? A 2026 analysis of nearly 40 randomized trials found chatbots showed a real but small reduction in depression symptoms. But most of these trials were compared to an alternative of no therapy, not a human therapist. So the benefit of AI therapy is probably real, but modest, and mostly untested against the alternative of human contact. We need more studies. Serious concerns OpenAI’s own estimate is that more than a million ChatGPT users each week show signs of suicidal planning or intent. These are high stakes encounters, and AI doesn’t always get it right. That’s partly because a chatbot can sound like a therapist, but it has no license, no duty of care, and it’s not clear who to hold accountable when it gets things wrong. AI is also designed to help users in whatever task they’re seeking to accomplish. People may feel like they’re getting therapy, but they’re mainly getting a convincing conversation. It’s easy for an AI companion to wander into gray areas, like playing along with “creative writing” that may be about the user’s own suicidal intent. Courts are driving safety conversations A wave of lawsuits have been filed on behalf of families claiming that chatbots pushed people they loved toward self-harm, including teens who died by suicide. The first settlements came this year. OpenAI is headquartered in San Francisco, and dozens of cases alleging that ChatGPT drove users to suicide or self-harm are now before a San Francisco judge. Character.ai has filed for bankruptcy after several states brought lawsuits accusing the chatbot of pushing dangerous content to kids. But the technology seems to be improving. Last month, an independent evaluation found that newer AI models “almost never endorse suicide.” That’s progress, but our societal appetite for even one preventable death is very low. So how do we move forward? Finding a middle ground Earlier this month the governor vetoed Senate Bill 903, a bill designed to place guardrails on the use of AI for therapy. The bill would have prohibited any AI-based platform from being advertised as psychotherapy, and would have required a licensed professional to review and approve each encounter where AI was used to support therapeutic decisions. Newsom called it overly broad, since even routine screening questions would have needed clinician sign-off. Knowing we’re already short on mental health providers, requiring human review of AI encounters may not relieve our access problems. Still, the answer isn’t no oversight. Here’s one feasible short term solution. Rather than reviewing each encounter, a licensed clinician can design the guardrails: what counts as a crisis, what triggers an immediate handoff to a human, and what gets sampled for audit each month. The AI runs inside that structure. Conversations get checked, failures get reported, and a real clinician owns the framework. Medicine already has models to learn from. The FDA process for rolling out newly approved medications is an example. After a product reaches patients, we keep watching for adverse events. Patient-facing AI needs the same “digital pharmacovigilance”: systematic tracking of harms, near misses, and the types of groups that get hurt and why. It’s also critical that users know that they can reach a human if they’re in crisis. Most chatbots now include messages like these: Bottom line The rush to use unproven AI tools for mental health support is mostly a workaround, a sign of a health system people can’t get into. We need better access to proven care from licensed clinicians. That takes reimbursement that makes accepting insurance viable, and a bigger workforce. But, built and tested well, AI could be part of the answer. It could be the 2 a.m. check-in when no one else is awake, or a way for patients to practice skills their therapist taught them. It could be the first step to get someone the right level of care, and take paperwork off clinicians’ plates so they spend more time with patients. None of this is simple. The SB 903 veto doesn’t end the debate, and the legislature will be back. In the meantime, those of us using these tools need to stay informed, ask hard questions, and hold the companies building them accountable. I’ll try to do my part, and we’ll keep learning together. Love,Matt P.S. If you or someone you know is struggling with mental health challenges, emotional distress, substance use problems, or just needs to talk, call or text 988- you’ll reach a real person— or chat at 988lifeline.org 24/7. Dr. Matt Willis is the author of Your Local Epidemiologist in California. A California native, he’s served as a primary care physician, CDC epidemiologist, and public health officer for Marin County, where he guided the pandemic response. He lives in Marin with his family and their dogs, Teddy and Ramona. Thank you Cynthia He, MD, PhD, and Parnika Saxena, MD, for their guidance in preparing this article. Cynthia works in an outpatient mental health clinic, treating patients who have Medi-Cal or, sometimes, no insurance. Parnika works in an inpatient psychiatric unit, treating patients with public or private insurance or self-pay ability. All opinions are their own and do not represent their employers.
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Plague is stoppable. The next health threat may not be.
The word plague is scary. Centuries ago, the Black Death killed tens of millions of people and changed the course of history. Plague still kills people around the world, and the word still evokes catastrophe. New fears of plague surfaced on October 2, when a lab worker in Irkutsk, Russia, died of pneumonia. Reports suggested that she may have contracted plague through a laboratory exposure. Understandably, people were alarmed. On October 7, the World Health Organization called for the Russian Federation to be transparent about what it knew. WHO issued an update on October 10. Russian authorities told WHO that testing did not identify plague and that investigations found no laboratory release. WHO said confidence in its risk assessment remained limited and that further clinical, epidemiological, and laboratory information was needed. The cause of the woman’s illness remains unknown, and WHO says a laboratory-associated exposure cannot be excluded. As I explained in a recent interview, this incident is very unlikely to lead to a pandemic. Plague is still active, including in the U.S., which sees a handful of cases each year. But it is a disease we can prevent and treat. Plague doesn’t spread readily, and it responds to antibiotics. The standard response—isolate the patient, trace contacts, and administer antibiotics and monitor for symptoms among contacts for seven days—works. We have even planned for antibiotic-resistant plague. At CDC, we developed a playbook for antibiotic-resistant plague and ran exercises on how to find and stop it. CDC guidance anticipates engineered resistance and recommends two different classes of antibiotics if there’s reason to suspect it. There is no evidence that resistance—or even confirmed plague—is involved in this incident. We have thought through how to address plague, but we’re not ready for the next major health threat that emerges from a lab or from animal spillover to humans. What should concern people is how little stands between the world and the next pathogen to get loose. Since peak COVID, epidemic preparedness has fallen off the political agenda, but the risk is greater than ever. More labs handle dangerous pathogens with more ways to make those pathogens deadlier, and more people live and work in close contact with animals. There are actions we can take now: We need better lab safety in every country. The number of labs that work with dangerous pathogens has increased worldwide over two decades, but there’s no enforceable international standard and no inspection regime; the Biological Weapons Convention, fifty years on, still has no verification mechanism. Labs that study dangerous germs need strong safety systems, training, and oversight. We need to reduce spillover events. Three in four emerging human infections start in animals, and there’s a lot we can do to reduce spillover risk, but the world is doing very little of it. Live-animal markets are one place to act. For instance, closing live-bird markets helped control H7N9 influenza in China. Reducing opportunities for people to encounter infected animals can prevent infections before they become outbreaks. In The Formula for Better Health, which is now out in paperback along with the hardcover, Kindle, and audiobook versions, I argue that labs do too many risky experiments with too many dangerous pathogens in too many institutions, and that every experiment should first answer one basic question: Is the likely benefit greater than the risk? Spillover risk can also be reduced: In the book, I discuss how Brazil cut its deforestation rate by 70% from 2004 to 2012 while increasing agricultural production and reducing risky contact between people and forest animals. We need faster detection and response. Delay costs lives. Strong surveillance, good labs, and trained responders can turn a single case into a small cluster of infections instead of an epidemic. Resolve to Save Lives has worked for nearly a decade to help countries find and stop outbreaks faster. The 7-1-7 target, which Resolve to Save Lives developed with partners in Uganda and elsewhere, provides a clear standard: detect within 7 days, notify within 1 day and complete all essential early response actions within 7 days. In Uganda’s Kasese district, for example, a review of a measles outbreak using 7-1-7 identified shortages of accessible funds, fuel, and vehicles that delayed the response. District leaders established funds they could access quickly. When, a few months later, the Crimean-Congo hemorrhagic fever appeared, the district detected it in three days, notified authorities in one, and mounted an effective response in two. Only one case was confirmed, and the patient survived. Because funds were available before the emergency, authorities were prepared and able to act. This kind of preparation can’t wait until the next crisis begins. Plague is an old disease we that know how to stop. The next threat may be harder to recognize, harder to treat, and easier to spread. Safer labs, less risk of spillover, and faster outbreak detection and response need sustained investment now, while we still have time to prevent the next emergency. Share
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