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The Last of Us Day Reveals Ghost of Yotei Collab Content and Ambience Video as Fans Beg Naughty Dog for TLOU 3
Naughty Dog has revealed it's celebrating The Last of Us Day 2026 with Ghost of Yotei content, player avatars on PlayStation and Steam, and an hour-long ambience video as fans continue begging for any updates on The Last of Us Part 3.
Scientists Have Developed a Breakthrough Energy Source to Fuel the First Humans on Mars
A NASA-backed experiment shows how engineered microbes can convert discarded water bottles into edible protein.
Power & Politics: New Charges for former State Sen. Dennis Bradley; one-on-one with Republican candidate for CT's 4th Congressional District
Dr. Don McAulay, of Quinnipiac University, and Republican Congressional Candidate Dr. Michael Goldstein join the show this week.
USADA Celebrates 25th Science Symposium by Advancing Detection of Peptides
USADA’s Annual Symposium on Anti-Doping Science marked its 25th anniversary with a focus on peptides and protein therapeutics.
Avex Music Group CEO Brandon Silverstein Expands Global Role as Avex Acquires His S10 Entertainment
/PRNewswire/ -- Avex Inc. (TSE: 7860) ("Avex"), the publicly traded global entertainment conglomerate led by CEO Katsumi Kuroiwa, has increased its ownership...
Rethinking Medicare home health
Liran Einav, Amy Finkelstein, Yunan Ji, and Neale Mahoney examine the design of the Medicare home health benefit. They assess the program’s objectives and offer reforms to better meet these goals.
FDA-approved epilepsy drug may help reverse osteoarthritis damage
Researchers at Yale have identified a promising new approach to osteoarthritis that could do more than simply ease pain. The epilepsy drug lacosamide appears to block a protein involved in both pain signaling and cartilage destruction, helping damaged joints shift back toward repair in preclinical studies.
Are sports & entertainment becoming the 'anti-AI trade'?
Turney Duff chats with Yahoo Sports staff writer Dylan Dittrich and Clocktower Group chief macro strategist Eric Wallerstein about how sports and the "entertainment economy" are emerging as attractive investments as the public's appetite for in-person experiences continues to grow.
'Very friendly territory': The politics behind President Trump’s Oklahoma rally
With President Donald Trump stumping in our state this evening, StateImpact’s Logan Layden talked with OU political science professor Allyson Shortle about the politics of the visit.
Trump’s mail voting crackdown tests Postal Service leader who says he’s ‘not political’
David Steiner once criticized Donald Trump’s leadership style after seeing him on “The Apprentice.” Nearly two decades later, he finds himself navigating Trump’s influence on the Postal Service.
Insects are essential to vertebrate life—as food, shelter and medicine
While insects provide an essential food source for many vertebrate species, they're more than just a protein-laden snack. Chimpanzees use them to sterilize wounds, and herons use them as fishing bait. ...
Colts’ Shane Steichen Reveals Unusual Post-London Plan
All good coaches have a plan when it comes to being strategic with schedules. A 17-game season can really be strenuous on the players' bodies and minds. This is why Steichen came up with a unique plan. He wanted to combat some of these challenges. The post Colts’ Shane Steichen Reveals Unusual Post-London Plan appeared first on HEAVY.
Yale School of Medicine On the Science of Childhood Anxiety, Say, Anxiety Disorders Are the Most Common Mental Health Challenges In Youth
Credit: Matt Bradbury October 5, 2026 - By Isabella Backman - Anxiety disorders are the most common mental health challenges in youth. Left untreated, they can disrupt the lives of both children and their families. The good news is that with intervention, most children will overcome these conditions. Across Yale School of Medicine, scientists are working to understand anxiety at every level, from common anxious behaviors to molecular biomarkers in the brain. They are using their findings to develop and disseminate new evidence-based treatments for childhood anxiety. Today, the go-to treatment for childhood anxiety disorders is cognitive behavioral therapy (CBT). This is a form of psychotherapy that teaches children skills for confronting anxious thoughts and helps them practice managing situations that cause anxiety. While it is the gold-standard treatment backed by considerable scientific evidence, up to 50% of children will not see sufficient benefit from CBT alone. Wendy Silverman, PhD, Alfred A. Messer Professor in the Child Study Center, co-directs the Anxiety and Mood Disorders Program alongside Eli Lebowitz, PhD, associate professor in the Child Study Center. One of their main interests is learning how to improve outcomes beyond CBT. “We’re developing cutting-edge, research-based knowledge that can reduce the suffering that anxiety causes children and their families,” says Silverman. Changing parent behavior YSM experts are investigating how to improve CBT outcomes for children by involving the parents. Silverman’s research has uncovered two main components of parent intervention that improve childhood anxiety: not enabling children to completely avoid the things that make them anxious and taking steps to enhance their autonomy. Parents may unintentionally reinforce their child’s anxiety by allowing them to avoid what makes them anxious. They also may unintentionally limit the children’s sense of autonomy by being overly intrusive. “One of the things that we take pride in is that we’ve focused on trying to understand what parents need to do, and to test our ideas and see if changing the parents’ behaviors is enhancing the effects of CBT,” Silverman says. “Our findings thus far suggest that they do." As much as CBT can be helpful, it can also be challenging to get one’s child to do the necessary steps for CBT to work. This is one important reason why Lebowitz created a novel intervention program for parents named Supportive Parenting for Anxious Childhood Emotions (SPACE). Existing intervention programs often teach parents to act as therapists for their child, such as training them on how to practice breathing exercises. “It makes sense, but this doesn’t work very well in practice,” says Lebowitz. “And part of the reason, I think, is that it’s not easy to get your kid to do things, especially if they’re not excited about doing it.” SPACE is unique because it focuses entirely on parent involvement and changing parental behavior—children are not involved in the sessions. For example, parents learn how to use supportive messages that convey confidence that their child can tolerate and manage distress. “It might sound like a parent saying to a child, ‘I get that this is really hard for you, but I know that you can handle it,’” Lebowitz says. The program also works with parents to identify the ways in which they are accommodating anxious behaviors. “We’ll pick one thing that parents are doing that is an accommodation and help them make a detailed plan for how they’re going to change that,” Lebowitz explains. Treating Anxiety in Children and Adolescents Much of the existing research on SPACE has focused on parents of children under age 14. Ongoing studies are now exploring its use with parents of older teens. “Both anxiety and accommodation can interfere with normative developmental shifts during the teen years, including increased autonomy and individuation from parents,” says Rebecca Etkin, PhD, associate research scientist in the Child Study Center. “In this sense, SPACE may be particularly well-suited for anxious teens and their parents. We want to see whether it is effective during this distinct developmental window.” Unfortunately, many families in need of CBT face barriers, including limited availability of services and geographic constraints. One way to improve access is digital interventions. Silverman and her team are developing an evidence-based digitized intervention program for parents that they can access directly from their computer or smart phone. “The work we’re doing will be one of the very few parent interventions that is digitized and importantly tested for effectiveness,” she says. Creating interventions for anxiety-related challenges Silverman and Lebowitz recently received a generous gift to develop and test other interventions that help parents reduce other child anxiety-related behavioral and emotional difficulties, such as restrictive eating and unexplained somatic symptoms. One of these projects in particular focuses on understanding the risks of social media and its potential benefits, including offering a sense of connection. “A lot of research has focused on the idea that social media is harmful and the less of it the better,” says Lebowitz. “But we actually see is that this is not quite right—there are negatives, but there are also positives. So, we’re trying to get a little bit more nuanced of a picture.” The team is working with teens with social anxiety and their parents over an extended period to better understand their social media habits and how their anxiety levels affect engagement with different platforms. The teens will answer questions sent to an app on their phones about mood and social media usage in an effort to capture emotional responses as they unfold. “We hope to develop interventions that can help make the best of social media while protecting against the more problematic effects,” Lebowitz says. The brain’s role in anxiety Researchers are also testing therapies to address anxiety at the neurological and molecular levels. In collaboration with Dylan Gee, PhD, professor of psychology in Yale's Faculty of Arts and Sciences, and Hilary Blumberg, MD, John and Hope Furth Professor of Psychiatric Neuroscience at Yale School of Medicine, Lebowitz and Silverman are using brain imaging to identify changes in a child’s brain before and after parents enroll in SPACE. In one study, children viewed anxiety-inducing images while undergoing magnetic resonance imaging (MRI); the researchers conducted scans with and without the children’s parents nearby. Before SPACE, children’s brains were better able to activate the regulatory circuitry needed to turn off an anxious response when their parents were nearby. But after SPACE, children could activate this circuitry even without the parent around. “As parents work on gradually reducing some of their accommodations, you can see a child get better at regulating their own fear system in the brain,” Lebowitz says. “It’s remarkable.” Research into the molecular underpinnings of anxiety can also inform new childhood anxiety treatments. In a recent study, Lebowitz, Silverman, and Flora Vaccarino, MD, Harris Professor in the Child Study Center, discovered that a protein known as fibroblast growth factor 2 (FGF2) could be protective from the toxic effects of stress. FGF2 levels in children and their parents were linked to the children’s risk of developing anxiety and depression, the study showed. The findings could help explain why some children who are exposed to early life trauma such as poverty or abuse are more prone to developing mental health disorders. And FGF2 could be a target for treatment. “This is very novel because it starts to give a clue to what is the molecular chain that connects those lived experiences to the actual psychological outcomes,” Lebowitz says. New ways to study and treat childhood anxiety Michael Crowley, PhD, associate professor in the Child Study Center, collaborates with Silverman and Lebowitz to study the role that attention plays in development and maintenance of childhood anxiety. There is a large body of research that shows that anxious children, like anxious adults, are prone to focus on threatening stimuli such as angry faces compared with neutral faces. This has led to innovative interventions that involve attention retraining. The idea is that if experts train children to look away from threatening stimuli, it may reduce their anxiety—especially children with social anxiety who are most prone to attend to threats. The researchers have just completed a clinical trial for attention retraining with 10- to 14-year-olds with social anxiety disorders and are currently analyzing the findings. Besides this innovative attention retraining research, as Crowly notes, “I like to design tasks that are engaging to kids,” Crowley says. “My goal is to assess something without the kids knowing what we are assessing.” With this goal in mind, Crowley has created a virtual game, named Boom, to study threat processing in children with anxiety disorders. The game is similar to that of hot potato—the child and three digital players take turns virtually passing a ball to each other’s gloves. At some point, the ball turns into a bomb, and as the bomb lands in each player’s glove, the outline of the glove turns yellow. The goal is to avoid having the bomb go off in your glove. What isn’t obvious is that the game is designed to measure different types of threatening stimuli, both ambiguous and direct. In the game, the direct threat occurs as the bomb is traveling towards your glove. The ambiguous threat is the yellow outlined glove as it is unknown where the bomb will travel next. While children play the game, Crowley’s team measures their brain activity using electroencephalography (EEG). The researchers have discovered that in kids with anxiety, the brain reacts more strongly to ambiguous threats than it does in their peers, but less strongly to direct threats. They believe that the initial abnormally large brain response to not knowing where the bomb is going impairs the brain's ability to properly respond when the threat is actually traveling the child’s way. “The brains of children with anxiety are unable to differentiate between threats you need to do something about and those that are not your problem.” Michael Crowley, PhD, develops innovative games for studying anxiety in children and adolescents.Credit: Matt Bradbury Based on these insights, Crowley hopes to study whether interventions like attention training could restore appropriate threat processing. Crowley’s team is also working on a test called the Balloon Risk Avoidance Task, which evaluates risk-taking and avoidance behaviors. It features a digital balloon that is full of air and about to burst. Kids have six seconds to let air out of the balloon. The more air they let out, the less risk they face that the balloon will pop. But at the same time, the balloon becomes less valuable as it deflates. “The more air you keep in the balloon, the more points you get,” Crowley explains. So far, the researchers have found that when the balloons pop unexpectedly, teens with social anxiety show distinct brain responses. Studying these responses can help psychologists understand the underlying pathways driving the various manifestations of anxiety. The genetics of anxiety When Thomas Fernandez, MD, associate professor in the Child Study Center and of psychiatry, was still in training, there was a lot of excitement about understanding the genetics associated with autism spectrum disorder. Since then, scientists have identified around 250 genes associated with autism. The genetic contribution to anxiety disorders, on the other hand, has historically received less attention. Anxiety is less heritable than autism, but the genetic contribution for anxiety disorders that emerge in childhood may be higher than for anxiety disorders overall. While scientists estimate the heritability of anxiety disorders in general to be around 30% to 50%, some studies suggest higher heritability for certain childhood-onset anxiety presentations. “I saw firsthand how researchers in the field went about finding vulnerability genes for autism,” Fernandez says. “So, we’re using a very similar playbook for childhood anxiety.” “I saw firsthand how researchers in the field went about finding vulnerability genes for autism. So, we’re using a very similar playbook for childhood anxiety.” Thomas Fernandez, MD Associate Professor In the Child Study Center and in Psychiatry Now, Fernandez and Emily Olfson, MD, PhD, assistant professor in the Child Study Center, are studying children and their parents to identify genetic changes that are present in the child but not the parents, known as “de novo mutations.” “All of us have some de novo mutations—maybe about 50 to 100 sprinkled throughout the genome,” Olfson says. “But when they occur within the coding regions of genes, they can be really disruptive.” Previous research shows that people with autism have higher rates of damaging de novo mutations than the general population. In 2022, Olfson, Lebowitz, Silverman, and Fernandez published a study on 68 children and their families that found that children with anxiety had similarly high levels of these mutations. Studying de novo mutations can help point the researchers to where they should be looking for genes associated with anxiety. “The end game is using the genes to steer us toward the right part of biology that we can then target to come up with better treatments,” Fernandez says. Building on those findings, the team is now studying more families to better understand how these de novo mutations, along with other genetic and environmental factors, shape pediatric anxiety disorders. They recently received a National Institutes of Health grant to enroll 750 new families over the next five years. Olfson is the principal investigator, with co-investigators Lebowitz, Fernandez, Silverman, and Shuangge Steven Ma, PhD, department chair and professor of biostatistics at Yale School of Public Health. Neurodevelopment, Risk Genes, and Mental Health Conditions - The Olfson Lab Joel Gelernter, MD, Foundations Fund Professor of Psychiatry, is interested in how different anxiety disorders differ genomically. “We are studying social phobia, panic disorder, and generalized anxiety disorder, working to understand why people differ in their risk to these specific anxiety disorders and evaluating various risk factors,” he says. Gelernter was recently involved in one of the largest studies to date of the genomics underlying anxiety disorder. The study included around 122,000 people with anxiety disorders and around 730,000 without. It found that some genetic differences associated with anxiety were linked to signaling that helps reduce overactivity in the nervous system. Many anxiety medications available today work by targeting this process. “It’s nice when the biology that you get out of a large genome-wide study ratifies things that we already know because that can help increase confidence in further findings from the study,” Gelernter says. Uncovering the neurobiology of psychiatric disorders John Krystal, MD, Robert L. McNeil, Jr. Professor of Translational Research and chair of the Department of Psychiatry, is interested in the neurobiology of psychiatric disorders, including post-traumatic stress disorder (PTSD), of which anxiety is a major symptom. In the late 1980s, Krystal’s team discovered that the drug yohimbine activated symptoms in patients with PTSD. “This was the first time we could link a specific biological mechanism to the symptoms of PTSD,” Krystal says. At the time, he adds, this finding was highly controversial. “A lot of people felt that PTSD was a purely psychological syndrome that didn’t have an underlying biology.” Since then, Krystal has dived deep into understanding the neurobiology of PTSD to learn how to better treat it. His team is evaluating the use of ketamine and psychedelics. These would be among the first treatments to be developed specifically for PTSD. They may also be applicable for other disorders including anxiety disorders, Krystal adds. An important gap in PTSD treatment is the absence of biological tests that inform how to best help patients manage their PTSD symptoms. A doctor doesn’t diagnose cancer based on how they feel. Rather, they use tests of the biology of the cancer to determine the best course of treatment. “And we can’t do that in any psychiatric disorder other than Alzheimer’s disease,” Krystal says. “But now we are building a foundation for this approach to the treatment of anxiety disorders for the first time.” Source: Yale School of Medicine
Norway parliament probes Epstein links to politicians, diplomats
Norway's parliament begins public hearings on Wednesday on ties between late US sex offender Jeffrey Epstein and Norwegian diplomats and politicians in a scandal that has shaken the nation's elite.
Maximilian Eggestein explains what makes ‘the perfect Freiburg player’
SC Freiburg midfielder Maximilian Eggestein has spoken at length on his role within Julian Schuster’s side, the importance of sacrificing individual ambitions for the collective and his plans to rem...
Avex Increases Ownership of Brandon Silverstein's S10 Entertainment
Japanese entertainment giant Avex Inc. owns 85% of Brandon Silverstein's S10 Entertainment with a shared goal of reaching 100%.
Fueling Performance: Kansas Checkoff Keeps Beef Front and Center in High School Sports
Targeting the next generation of beef consumers, the initiative reinforces beef’s role as the premier protein for athletic fueling and recovery.
Optimum Nutrition unveils multi-functional shakes
The protein shake features 30 grams of protein, 8 grams of fiber.
Sony introduces AI upscaling to base PS5; Marvel's Wolverine and Ghost of Yōtei are first games to implement new tech
PlayStation Spectral Super Resolution (PSSR) remains exclusive to the PS5 Pro, which SIE says is the "gold standard"
Avex expands stake in S10 Entertainment and targets full ownership
Japanese music company Avex has expanded its stake in management firm S10 Entertainment by acquiring 85% of the company.
Gov. Stein and NCDHHS announces $17 million for rural mental health services
North Carolina will invest more than $17 million to expand rural mental health and substance use services in multiple ENC counties, including crisis-response te
Ginkgo Bioworks to Provide Autonomous Lab Access to NSF X-Labs Researchers, Contributing Cloud Lab Time and Protein Testing Services to $1.5 Billion Breakthrough Science Program
Ginkgo Bioworks (NYSE: DNA) today announced that it will provide in-kind access to its autonomous laboratory in Boston to support the National Science Founda...
Sony announces QSSR AI upscaling tech for base PS5 in Marvel's Wolverine and Ghost of Yōtei
The PS5 Pro is no longer the sole domain of AI upscaling tech on console.
Leucine does more than build muscle. It powers up your cells
The essential amino acid leucine can boost cellular energy production by protecting key proteins on mitochondria from being destroyed. The discovery reveals a new connection between nutrition and metabolism that could eventually lead to new approaches for metabolic disorders and cancer.
Yankees news: Feeling like home
Yankees train at George Steinbrenner Field, Game 2 is a "must win," ALDS "far from over," Wells explains blunder
Fibermaxxing is trending. Here’s what the science says
Fiber is the new protein. Here's what dietitians say about fiber, health and the "fibermaxxing" social media trend.
The pilot of 'Veep' established Julia Louis-Dreyfus a generational talent
The show, which ran until 2019, firmly established Julia Louis-Dreyfus as her own generational comedic talent.
Studying Science in an Anti-Scientific Time
This Chronicle Review Deep Cut was first published in 2025. By Julianne Werlin Thanks for reading The Chronicle Review! Subscribe for free to receive new posts and support my work. Subscribe The last two decades have not been kind to science studies. Already bruised and battered by the “science wars” of the 1990s, by the 2000s sociologists of science — who had long argued that science had to be understood in its human context — were encountering the funhouse-mirror version of their own views in right-wing critiques of climate scientists. It was enough to give some prominent scholars pause. “Was I wrong to participate in the invention of this field known as science studies?” asked Bruno Latour, the most famous sociologist of science in the world, in 2003. “Should we apologize for having been wrong all along? Or should we rather bring the sword of criticism to criticism itself and do a bit of soul-searching here: What were we really after when we were so intent on showing the social construction of scientific facts?” In response, Latour proposed a change of method and attitude. Science studies, now chastened and contrite, would no longer seek to strip facts of their authority, but to enrich and enhance them. What this meant in practice was never fully clear. But his diagnosis of problems resonated, even if his solutions did not. Latour’s exercise in public hand-wringing signaled a shift in mood. By 2016, with the first election of Donald Trump, the idea that skepticism of science was a right-wing position, not a left-wing one, had become a commonplace, discussed eagerly in The New York Times. For liberals, vaccine denial during the Covid era and Trump’s second-term attacks on the funding of scientific research, covered extensively in these pages, added a new urgency to the defense of science on both practical and principled grounds. There was little appetite for a sociology or philosophy of science that emphasized the messiness and missteps of the scientific process rather than its integrity and triumphs. The distinguished historian of science Peter Dear’s new book, The World as We Know It: From Natural Philosophy to Modern Science (Princeton University Press, 2025), which seeks to tell the story of 18th- and 19th-century science for a general public, may seem comfortably remote from these bitter contests. In its 16 short chapters, Dear draws swift, sure sketches of major discoveries from Newton to Einstein, ably guiding the reader through debates on stellar nebulae, animal taxonomy, atomic chemistry, evolution, and other flashpoints in the history of science. But though a work of history, Dear’s book must still negotiate our polarized present. In a blurb on its back cover, the historian of biology Lynn K. Nyhart alludes to the “present moment, when scientific knowledge is being swamped by misinformation and its institutions are under siege.” Dear himself, in his conclusion, refers to the “yard signs” and “bumper stickers” that proclaim “Science Is Real.” One antidote to both anti-science propaganda and to reductive slogans in science’s defense is a robust history and philosophy of science: exactly what Dear’s scholarship has long offered. But his new book illustrates how difficult such work has become. Dear, an emeritus professor of history at Cornell University, is best known as a creative and philosophically minded historian of the Scientific Revolution. His edited volume The Literary Structure of Scientific Argument (1991) analyzed the rhetoric of Galileo’s thought experiments to brilliant effect. Discipline and Experience: The Mathematical Way in the Scientific Revolution (1995) was a major contribution to the analysis of scientific experiments in early modern Europe and beyond, while Revolutionizing the Sciences: European Knowledge in Transition, 1500-1700 (2001), now in its third edition, remains one of the best overviews of the profound epistemological upheavals of 16th- and 17th-century science. But Dear has also ventured into later periods. Nearly two decades ago, in The Intelligibility of Nature: How Science Makes Sense of the World (2006), he turned to the 18th and 19th centuries to sketch a history and theory of scientific knowledge. Aimed at a generalist audience, Dear’s simple prose belied serious philosophical ambitions. Science, Dear argued, has two aspects: “natural philosophy,” the quest to understand the true nature of the universe, and “instrumentality,” the applied skills and technologies that allow us to manipulate the world for human advantage. Both strands are ancient, but the innovation of the phenomenon we call “science” was to yoke them together. As Francis Bacon wrote, “Human knowledge and human power meet in one; for where the cause is not known, the effect cannot be produced,” an insight typically abridged to “knowledge is power.” Or, in Bertrand Russell’s characteristically blunt phrase, science has two functions, “1. to enable us to know things, and 2., to enable us to do things.” So far, so conventional. But Dear took issue with this familiar story in one respect. Bacon’s formula implied that theory and practice could be fused in a single method. In fact, Dear argued, the quest to understand nature and the desire to manipulate it were coupled only loosely. They could come together, but they could also pull apart. Focusing on natural philosophy, the “knowing” half of the scientific circle, he used a series of case studies from cosmology, taxonomy, chemistry, electromagnetism, and quantum theory to show how theories changed over time, in dialogue with practice, but never reducible to it. Take the case of matter, the basic substrate of the physical world. In the 18th and 19th centuries, scientists not only disagreed about what it was, but also about how well it could be known. In 1789, the chemist Antoine Lavoisier dismissed speculation about the atomic composition of chemicals as “discussions entirely of a metaphysical nature,” as he sought to orient chemistry away from philosophical abstraction and toward laboratory results. But in the 19th century, atoms returned with a vengeance in the atomic chemistry of John Dalton, who wanted to explain the underlying structure of nature. It was not just that Dalton and Lavoisier had a different set of experimental results, or even a different theory, Dear showed. What counted as an explanation had changed. In arguing that scientific theories depended on their intelligibility to human beings with complex arrays of beliefs and commitments, Dear was in sympathy with science studies. Key figures such as the sociologist Steven Shapin emphasized the importance of psychological mechanisms like trust in the formation and acceptance of scientific ideas. But in focusing on the scientific pursuit of knowledge, not its politics or economics, Dear resisted the more cynical perspective of some of his colleagues. The Intelligibility of Nature strikes a very different note than Shapin’s collection of a few years later, Never Pure: Historical Studies of Science as If It Was Produced by People With Bodies, Situated in Time, Space, Culture, and Society, and Struggling for Credibility and Authority (2010), to name just one example. Walking a very fine line, Dear depicted science as driven at once by complex social dynamics and by the intellectual power of real discoveries. It was a testament not only to his own acumen but also to the vitality of the field that he was able to do so. Nearly two decades later, The World as We Know It returns to the questions broached in The Intelligibility of Nature. Like Dear’s earlier study, it begins with the Newtonian cosmos and ends with debates between Einstein and Bohr on quantum physics. Beyond its terminal figures, many of the same characters appear in both studies, including the naturalists John Ray and the Comte de Buffon; the chemists Étienne François Geoffroy, Antoine Lavoisier, and John Dalton; as well as Charles Darwin and Michael Faraday, among others. Its subject is nearly identical: As in The Intelligibility of Nature, The World as We Know It considers natural philosophy as opposed to instrumentality, here defined as the “desire to create a picture of what the world is really like — the world as God knows it — rather than simply having instrumental or operational control over it.” The two books also overlap in insights — and sometimes even in language. The reader who has learned in The Intelligibility of Nature that Buffon’s method of classifying animals “reflected his belief in the importance of the senses and empiricism in learning about nature (a doctrine associated with Newton and the philosopher John Locke)” will experience a sense of déjà vu on reading, in The World as We Know It, that the classification “reflects Buffon’s commitment to the epistemological stance of Newton and his philosophical underlaborer John Locke, who stressed the role of the senses in creating natural knowledge.” Later in the passage, we read that, “because of its stress on understanding the ways of life of animals in their environments, Buffon’s approach could almost be labeled (anachronistically) as ‘ecological.’” And again, “an anachronistic way of putting it would be to say that Buffon recommends an ecological mode of understanding.” Likewise, in The Intelligibility of Nature we read of Dalton that he was initially drawn to meteorology, and that: He did a bit of experimental work on these things, especially having to do with the water-holding capacity of gases, but his real interest lay in understanding what, at an underlying natural-philosophical level, was really going on physically.” Whereas, in The World as We Know It: He did experimental work on these things, especially concerning the water-holding capacity of gases — although not at a very refined level quantitatively — but he was continually trying to develop a theoretical conception of what was happening physically. The final full chapter of each book closes on the same resigned note. Intelligibility: These days, most serious work on the natural philosophical underpinnings and implications of quantum mechanics is performed not by physicists but by philosophers of science. Among scientific practitioners themselves, Bohr’s attempt to use instrumentality as sufficient grounds for a respectable science has met with a high degree of success. And again, in The World as We Know It: Bohr’s and Einstein’s concerns are now questions that are mostly discussed by philosophers of science rather than by physicists themselves. The marginalization of these sorts of questions amounts to the demise of natural philosophy, at least in physics, in the 20th century. Quantum mechanics “works,” and that’s good enough for most scientists who encounter it. Examples could be multiplied. When handling the same subject matter, some echoes are inevitable. Scholars should not feel that because they have written “Isaac Newton died in 1727” in one book, in the next they must describe him as perishing, expiring, or meeting his maker. But the repetitions of language and arguments (not to mention six reproduced images) threaded throughout The World as We Know It are more extensive than that. They should have been caught by Princeton University Press or its reviewers, and revised. Because the two books have so much in common, it is easy to see where they diverge. The World as We Know It is a less theoretical work than its predecessor. The sociology of knowledge that organized The Intelligibility of Nature has been reduced in scale and folded into readings and examples. The taut interplay between history and theory, which gave the earlier study so much interest, is there, but it is subtle. In the earlier book, the case studies demonstrated theoretical claims about the character and development of science. In the later work, each narrative of discovery is an end in itself. Insights emerge from the history, but they do not control the organization of the study. With the theory muted, it can be hard to understand the logic uniting Dear’s sprawling history of more than two centuries of scientific knowledge. The 16 brisk chapters cover an enormous amount of material. But the closer the volume edges to comprehensiveness, the more obvious the missing elements become. A chapter on “Institutions and Pedagogy,” describing the birth of the research university, illustrates the problem. Inserted roughly halfway through the book, the unnumbered chapter is designed as an “entr’acte,” in acknowledgement that it does not fit the study’s organization around scientific discoveries. Yet as Dear is well aware, no general history of the development of modern science can bracket its 19th-century institutionalization and professionalization. It was the 19th-century university, after all, that gave us the “scientist,” a term coined by the Cambridge philosopher William Whewell. Dear’s history of scientific discoveries implies a wider social and institutional history, but it remains largely subterranean, only occasionally extruded under the pressure of the narrative. It must be said that the balance is not all on the side of the earlier study. There are some advantages to the more historical, less theoretical organization of The World as We Know It. Dear’s accounts of paradigm shifts are remarkably lucid, no small accomplishment given that they span fields and centuries. He makes excellent use of the wealth of new scholarship on Darwin and his influences, to which he has himself contributed. It is satisfying to see puzzle pieces from Buffon’s natural history, Georges Cuvier’s animal taxonomy, Thomas Robert Malthus’s demography, and Charles Lyell’s geology recombined seamlessly in the Darwinian jigsaw. Likewise, Dear’s discussion of stellar nebulae, divided between chapters two and 15, shows vividly how Newton, Kant, Herschel, and Hubble reimagined insights and observations as they sought to discover whether the diffuse light that filtered through early telescopes was a glowing, gaseous substance or discrete but distant stars. Yet despite such pleasures, the book remains a more modest work than The Intelligibility of Nature. Dear has clearly not changed his views about the history of science. But in the two decades that have elapsed, the discipline and the world around it have changed, making it harder to write a sociologically and philosophically ambitious history of science for the general reader. That is a shame, because in the age of Silicon Valley and biotechnology, both the reciprocity and the tensions Dear identified between the epistemological and instrumental ambitions of science are more evident than ever. In recent years, some of the most exciting new books on the history of science in early modernity have focused precisely on this pressure point. Important studies such as Pamela H. Smith’s From Lived Experience to the Written Word (2022), James Poskett’s Horizons: The Global Origins of Modern Science (2022), and Vera Keller’s The Interlopers: Early Stuart Projects and the Undisciplining of Knowledge (2023) all shed new light on how early modern science negotiated the relationship between its instrumental and epistemological ambitions, or in Russell’s phrase, knowing and doing. There is every opportunity for a philosophically informed approach to draw new insights from this wealth of material. Dear, unfortunately, has not done so in The World as We Know It. But for future scholars of the history of science, his body of work over nearly four decades may provide just the model. Julianne Werlin is an associate professor of English at Duke University. 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Sony Brings AI Upscaling To The Base PS5
Marvel’s Wolverine and Ghost of Yōtei are the first games to support Quick Spectral Super Resolution.
Is It Healthy to Eat Nuts Every Day? Yes, If You Avoid These 3 Things, Dietitians Say
Nuts are rich in healthy fats and plant protein. Here’s the healthiest way to enjoy nuts every day, according to dietitians.
Gov. Stein announces $20M fund to increase health care access in rural North Carolina
A new fund will increase access to health care in rural parts of North Carolina.
SIG: Material science drives next generation of aseptic packaging
Scientific developments and material innovations have pushed aseptic packaging research beyond its conventional role in preserving products.
Avex Acquires Majority Stake in S10 Entertainment, Expands Brandon Silverstein’s Global Role
Avex Inc. (TSE: 7860) has increased its ownership of S10 Entertainment, acquiring an 85% stake from founder Brandon Silverstein and... Read More
Charley Steiner will call Dodgers postseason home games on radio
LOS ANGELES — Every game of the Dodgers postseason, from the National League Division series to — should they advance — the National League Championship Series and World Series, will be televised by Fox Sports. But on radio, Charley Steiner will call Dodgers home playoff games at Dodger Stadium for AM 570 and the team’s […]
State investing over $17M in mental health service grants
Governor Josh Stein and the state Department of Health and Human Services made the announcement today.
PS5 gets "AI-guided upscaling" a bit like PS5 Pro's, and it's available now in Marvel's Wolverine and Ghost of Yotei
AI upscaling was previously exclusive to PS5 Pro, but base PS5s are getting a watered down version, and it's available now.
Using comic books to get serious about science
Nuclear engineer-turned-librarian Jim Ottaviani found his niche as a writer of nonfiction comic books about scientific superheroes. Move over, Marvel. Step aside, DC Comics: Einstein, Pasteur, and more, have muscled their way into the best-seller stratosphere.
Better together: How to pair protein and fiber
Learn how to pair protein and fiber for more satisfying meals. A dietitian shares simple protein-and-fiber food combinations to try.
Hannah Pingree campaign returns donations from former Epstein attorney
The contributions to her campaign from Paul Hoffman, first reported by the Portland Press Herald, came in over the spring.
SJ Cafe in Loves Park has closed. The business is for sale
By Kevin Haas Rock River Current Get our mobile app LOVES PARK — A locally owned cafe that centered on quick grab healthy options such as smoothies, wraps, parfaits and protein bites has closed after less than a year in business. SJ Cafe, 6731 Broadcast Parkway, announced its closure on Monday via Facebook. Owner Danna
Blood Proteins May Offer New Clues to Gut Health in Coeliac Disease
Coeliac disease is an autoimmune condition in which the immune system reacts adversely to gluten. Eating gluten causes inflammation in the gut, which can damage the intestine and impair its ability to absorb nutrients.
Protein sciences in drug discovery 2026
ELRIG’s Protein Sciences in Drug Discovery 2026 meeting will be held at GSK Stevenage (UK) on November 10th-11th 2026.
Colts' Steichen evaluates Sauce Gardner's early impact
Shane Steichen evaluated the early impact that Colts' CB Sauce Gardner has made this season.
Politics on Stage. Wonderful Life on Broadway. Jeremy O Harris to Mamdani: Call me. Stageworthy News of the Week.
On stage during the first week of October: Plays about the Epstein Files. Gun violence. Black women silenced. Complicity. Sexism. Homophobia. This seems an unusual burst of political theater even f…
A day in the life of Fishwife CEO Becca Millstein
Fishwife co-founder and CEO Becca Millstein adapts to her fast-growing business by keeping her personal routine as simple and stree-free as possible.
Governor’s advisory council discusses Youth Risk Behavior Survey ahead of final policy recommendations
Gov. Stein's advisory council is finalizing recommendations on youth well-being before the legislature decides how to use Meta settlement funds.
Massie's Epstein bill push approaches required signatures
The measure is on hold for now because the House is out of session until after the November election.
Blood proteins may offer new clues to gut health in coeliac disease
Coeliac disease is an autoimmune condition in which the immune system reacts adversely to gluten. Eating gluten causes inflammation in the gut, which can damage the intestine and impair its ability to absorb nutrients.
Francis Halzen wins 2026 Nobel Prize in physics
Among past laureates are some of the most celebrated figures in science, including Albert Einstein, Marie and Pierre Curie, Max Planck and Niels Bohr.
Business People: Hilton exec Mark Weinstein to lead Target marketing
RETAIL Target Corp., Minneapolis, announced that Mark Weinstein has joined the company as chief marketing and guest experience officer. Weinstein joins Target from Hilton, where he served as global chief marketing officer for all 28…
Newport Mental Health is building a network of care for Newport County
We asked Newport Mental Health President and CEO Dayna Gladstein to tell us more about the organization.
A lawsuit accuses Starbucks of mislabeling 8 'sugar-free' protein drinks
Starbucks is facing a consumer lawsuit over claims that the protein drinks labeled as “sugar-free” on its cafe menus may actually contain more sugar than a Reese’s peanut butter cup.
SFFILM to honor ‘Project Hail Mary’ with Sloan Science in Cinema Prize
Past winners include Oscar Best Picture nominees Oppenheimer, The Martian, Hidden Figures, Don't Look Up, and Frankenstein.
Land O’Lakes Bulks Up Its Protein Capacity
The cooperative is expanding its processing facilities to capitalize on consumer demand for more protein products.
SLR Business Credit Provides $10MM Senior Secured Asset-Based Credit Facility to Markstein Sales Company
SLR Business Credit (SLRBC) closed a $10 million senior secured asset-based credit facility to Markstein Sales. The facility is secured by the company’s
Leader of Jewish Greens calls for Zack Polanski to resign
Vivien Lichtenstein says party leader should stand down over ‘Zionism is racism’ policy after losing byelection
German politicians warn of antisemitism on October 7 anniversary
Leading German politicians including Chancellor Merz and President Steinmeier called for people to reject antisemitism.
The Harvard Crimson (@theharvardcrimson)
83 likes, 0 comments - theharvardcrimson on October 6, 2026: "Harvard’s Faculty of Arts and Sciences is launching 25 tenure-track faculty searches, FAS Dean Hopi E. Hoekstra announced in a Monday email to faculty, further loosening a University-wide hiring freeze instituted last spring as the school draws an influx of philanthropic support. The searches, which include positions across the FAS’ three divisions and the School of Engineering and Applied Sciences, come less than a week after Hoekstra announced the school would also be upping Ph.D. admissions for the upcoming admissions cycle — and as the University continues soliciting support from donors for its academic programming. Full story linked in bio. 🖋: Abigail S. Gerstein and Amann S. Mahajan 📷: Mae T. Weir".
Experts say a heart-healthy diet is more about consistency than chasing trends
A new ACC scientific statement looks at how eating well can help with the prevention and management of CVD. Plant-based foods as well as healthy fats and proteins are recommended over foods high in refined starches, added sugars and unhealthy fats.
Governor Stein announces $20 million fund to increase access to healthcare in rural North Carolina
$20 million fund aims to expand healthcare in rural North Carolina
Goodbye joint replacements? Stanford scientists found a way to regrow cartilage and stop arthritis
Scientists have found a surprising way to regrow damaged knee cartilage by blocking a protein that becomes more abundant with age. In old mice, the treatment restored naturally lost cartilage and also helped prevent osteoarthritis after ACL-like knee injuries, while human cartilage taken from knee replacement patients began producing new, functional joint cartilage after exposure to the same inhibitor.
Massie's Epstein bill push approaches required signatures
The measure is on hold for now because the House is out of session until after the November election.
New Star-Filled Movie Directed By Hyatt Hotel Heir Filming in San Francisco
Filming for an upcoming movie titled 'Fog City' has taken over two blocks of Steiner Street this week, with a cast that reportedly features Miranda Otto, Cooper Koch, and Angus Imrie. The picture is being directed by billionaire Hyatt hotel heir Daniel Pritzker.
A Slice of Joy: In Conversation With 'Mystic Pizza' Performer Teisha Thomas
We caught up with powerhouse performer Teisha Thomas, who serves up heart, hits, and hospitality in 'Mystic Pizza' at the Ordway.
Ghost of Yōtei’s New DLC Should Have Been in the Game from the Very Start
Echoes of Sekigahara allows Atsu to be so much more than just the Onryō
Heartland Catfish Unveils New Website
Heartland Catfish Company recently launched a new website in celebration of its 30th anniversary. The site has been refreshed to focus on retail and food service partnerships, give a detailed look at the company’s products and processes and emphasize consumer education about the benefits of U.S. Farm-Raised Catfish as a versatile and healthy protein source. […]
Political analyst on Trump's campaign stop in reliably red Oklahoma
NPR's Steve Inskeep speaks to political analyst and columnist Ron Brownstein about President Trump's pre-midterm campaign visit to the Republican-majority state of Oklahoma.
Democrats release midterms ad featuring family of Epstein victim Virginia Giuffre
(CNN) — The campaign arm working to elect House Democrats released a political advertisement on Monday featuring the family of Virginia Giuffre, who was the first victim of Jeffrey Epstein
Reclaiming 'Health Sovereignty': EU Gastein Forum Confronts A Fragmenting Global Order
Health, long treated as a sanctuary of diplomatic consensus, has entered an era of high politics and ideological division. Leading the closing panel of the EU Health Forum Gastein (EHFG) on Friday (2 October), session chair Ilona Kickbusch, founder of the Global Health Centre at the Graduate Institute in Geneva, highlighted how recent votes at the UN General Assembly demonstrate that nation-states increasingly split and vote instead of searching for consensus.
Scientists Find a Hidden Network of Tiny Channels The Brain May Use to Flush Out Toxic Alzheimer's Proteins
Toxic proteins need an exit.
Netflix’s Summer of Bummer
(Welcome to the Entertainment Strategy Guy, a newsletter on the entertainment industry and business strategy. I write a weekly Streaming Ratings Report and a bi-weekly strategy column, along with occasional deep dives into other topics, like today’s article. Please subscribe.) Today, I’ve got a guest post from longtime friend of the newsletter, Brandon Katz. I’ve been trying to find time all summer to look at Netflix’s straight-to-streaming film slate, but between a pre-planned trip and Nielsen moving up their streaming data timeline, I’ve been swamped. So I reached out to Brandon, one of my favorite fellow analysts, to write about it. And I feel like he captured the tone and data focus of the newsletter perfectly. You can connect with Brandon on LinkedIn and Twitter. Enjoy! Don’t worry, folks. You’re in safe hands with me. To ease any anxieties about an interloper in ESG’s domain, I’ll start by stealing one of his best framing devices: headlines. Box office flops are covered in the same way the Teenage Mutant Ninja Turtles eye pizza: with cartoonish insatiability. I would know. I’m a former reporter who wrote nearly identical headlines: Yet, intentionally or not, streaming misses get treated with kids gloves, filtered through a rosy lens: In the last six years, U.S. streaming viewership has become nearly as transparent as the box office, but the data often arrives weeks later, in a number of less intuitive metrics, and with nary an official budget to be found. This plays into the Wall Street-whispering narratives major streamers have been cultivating for years. They get a pass in a way that theatrical studios simply don’t. Subscribe Netflix’s Summer Slate Not a single Netflix original film released between May and August this year opened above 20 million U.S. TV hours, per Nielsen. That benchmark usually serves as the EntStrategyGuy’s floor for a streaming hit on Netflix. None of these films enjoyed a hit-cementing single week of 20-plus million hours during their runs. Netflix’s two best films were true crime docs, Maternal Instinct (16.5 million hours) and The Crash (19.7 million), the best overall week for a film this summer. Great for most other streamers, but not necessarily what we’re used to seeing from Netflix. For an overly-dramatic comparison, Happy Gilmore 2 opened last summer to around 47 million hours (celebrity cameos, baby!). Zooming out, the picture looks even worse. In 2026, Netflix’s five biggest scripted summer films posted the lowest average (28.6 million hours) and median (28.8 million hours) eight-week viewership totals of the past four years. Now, it’s unrealistic and unfair to expect Netflix to deliver a _KPop Demon Hunters-_sized hit every year. But it’s also not ideal to see the size of their hits shrinking over the last few summers. Let’s quickly run through some of the notable summer misses. Jennifer Lopez and Brett Goldstein’s perfectly fine romcom, Office Romance, fell off the charts after 20 million hours in its first two weeks. Top films usually last for four-plus weeks. Starry titles ideally don’t decay that fast either. Homegrown star Millie Bobby Brown couldn’t prevent the snappy Enola Holmes franchise from diminishing returns. At 14.3 million U.S. hours, the third film posted roughly half of what the first two films did in their first two weeks. What’s on Netflix calculated that per-day global views were down nearly 60% from the second movie. The Whisper Man did okay with more than 36 million hours over its first four weeks. But I expected a little more juice from a film featuring Robert De Niro, Michelle Monaghan, and Adam Scott. Kevin Hart’s Ladies First collected just 11.2 million hours total across two weeks. That’s a big miss for one of Netflix’s go-to stars. Plopping into the same bucket are Sunny Sandler’s Don’t Say Good Luck (10.3 million in two weeks) and John Cena’s Little Brother (17.5 million). Meanwhile, English-language originals Color Book (June 19), In the Hand of Dante (June 24) and Heartstopper Forever (July 17) never sniffed Nielsen’s Top 10 at all, despite needing only 2 to 5 million hours to land in the top ten most weeks. (By my count, eleven English-language scripted original films released between May and August did chart). It’s only fair to mention that Swapped (1-May) posted nearly 42 million U.S. hours over five weeks (the longest Netflix original run this summer) and is currently their eighth most-watched English-language film ever worldwide. Remarkably Bright Creatures (37 million, 4 weeks) and Voicemails for Isabelle (27 million, 4 weeks) weren’t bombs either. Still, overall, I think it’s fair to say this was a quieter summer season than we’re used to seeing from the market-leader. You might not realize that given the language commonly used in public analysis. The Twist Despite the starkly black-and-white tone of the coverage, here’s the twist: when many box office bombs arrive on streaming, their viewership looks a whole lot like many of Netflix’s supposedly successful summer releases. Hmm, where have we heard that one before? Masters of the Universe topped out at $65 million stateside against a $170 million budget_._ I’ll admit, Skeletor ripping sleeveless curls as a gym bro and bodyslamming Adam’s co-workers was funny. But, much to the chagrin of my bank account, my laughter doesn’t launch franchises. Yet the He-Man reboot opened to 19.6 million hours (from a Wednesday five-day opening instead of just one weekend), on par with Hoppers on Disney+ (19.4 million). It put up nearly 47 million hours over its first six weeks, bigger than all of Netflix’s summer releases. Pretty darn healthy and likely to land among the 25 most-watched movies on streaming this year. Sticking with Amazon, The Sheep Detectives just barely broke even at the box office with $133 million worldwide (and only $66 million domestic). I never expected cloven-hooved, cud-chewing mammals to be able to bring me to tears. Yet that’s exactly how I found myself at the end of this surprisingly affecting movie (#NoShame). It was likely the unexpected quality in a family-friendly film that powered its streaming over-performance. Sheep Detectives delivered a solid run for Prime video netting 26.2 million hours! How about franchise IP? Star Wars: The Mandalorian & Grogu had the lowest opening ($81 million) and lowest-grossing Disney-era live-action Star Wars film ($178 million domestic). One day before release, its Heat score (19.8%)—audiences who list their interest as a 7/7—fell behind blockbusters Wicked (21%), Superman (23%), Fantastic Four: First Steps (23%), Michael (23%), Toy Story 5 (26%) and Avatar: Fire and Ash (27%), according to Greenlight Analytics. The urgent enthusiasm just wasn’t there. On streaming, Mando opened to weeks of 12.1 million, 6.1 million and 2.7 million hours (21 million total) over its first three frames. Not the numbers Lucasfilm was hoping for nor the numbers of a streaming hit. But they’re in the same vicinity as some Netflix summer releases with $345 million at the global box office to offset a smidgen of the pain. Final Thoughts So why oh why does this nuance gap exist? Four key reasons: Data Literacy: A “$100 million opening” just makes sense. After decades of box office reporting, even casual movie fans are well-versed in the benchmarks of hits and home runs. There’s an immediate shorthand. But “16.5 million” hours doesn’t land nearly as cleanly. Despite leaps of progress, the streaming ratings era is still in its infancy compared to theatrical. The EntStrategyGuy and I met thanks to a late 2010s group chat of data nerds hungry to find a shred of certainty in nebulous streaming performance. I’m not surprised to see “No. 1 on Netflix” still getting misconstrued out in the wild. Timing: By Friday morning, we have the box office’s Thursday night previews totaled, allowing us to better project the weekend’s expectations. From there, ticket sales are reported daily. By Sunday, the film’s fate is usually finalized, at least in terms of public perception. In streaming, Nielsen recently improved its delay to…two weeks. The medium isn’t forced to contend with instant gratification as harshly. Financials: Theatrical film budgets are a mere Google away. Profit and loss is calculated in the cold and unforgiving naked light of day for all to see. But finding the vast majority of streaming exclusive movie budgets requires the forensic investigation skills of a Criminal Minds detective. Also, it’s very difficult to calculate how much revenue/value a straight-to-streaming films provides a streamer. This is why there are so few stories about streaming original movies “losing X amount of money”. On top of that, marketing budgets are far greater for theatrical movies than streaming exclusive movies, which leads to earlier and better awareness. This then translates to a wider pool of potential interest. Narrative Control: Netflix is the only major streaming service to publish weekly first-hand viewership data and annual engagement reports. Naturally, some headlines borrow their first-hand framing**.** Other streamers benefit from their comparative lack of transparency. They may occasionally announce vague performance platitudes such as Apple TV’s Mayday becoming its “biggest film debut on the platform to date over its first 18 days,” and that it ranked No. 1 with left-handed viewers in its first weekend. (Fine, I made up that second one). But, for the most part, they keep first-hand viewership shrouded in mystery to avoid bad press. Especially for outlets that demand multiple articles per day from their writers, it’s an easy (and understandable) way for some reporters to hit their daily article quota by just repeating what the streamers have told them. TL:DR version: Streaming-exclusive movies are asked to do different things than theatrical movies, but that doesn’t mean they should escape judgment. Both still need to draw enough eyeballs to justify their cost within the proper performance contexts. The more cleanly we can inject a little nuance into streaming analysis, the better we’ll understand the audience and content trends that drive this industry. And that’s what all of this is really about: knowing what audiences actually want! Brandon Katz is the Director of Insights & Content Strategy at Greenlight Analytics where he focuses on evaluating the ever-fluid media landscape to unearth understanding, opportunity and value. Greenlight Analytics is the entertainment intelligence consulting company redefining how Hollywood finds, understands, and activates audiences. Prior to joining Greenlight Analytics, he served as the senior entertainment industry strategist at Parrot Analytics, and as a full-time entertainment industry reporter covering the Xs and Os of Hollywood, most notably with TheWrap and the Observer.
UK author and politician Jeffrey Archer dies aged 86
Jeffrey Archer, the best-selling British novelist and former politician who was jailed for lying in a high-profile libel case, has died aged 86, his publisher HarperCollins said on Monday.
Biden-era FBI’s ‘Nixonian’ Trump family surveillance draws scrutiny from unlikely corner
Julian Epstein, a former top Democratic official, compared the FBI's tracking of Melania Trump, Barron Trump and Susie Wiles to Nixonian tactics.
Review: Ghost of Yotei: Complete Edition (PS5) - Atsu Shines in Story DLC, But Most Wanted Mode Steals the Show
Wanted dead
25 Years of Business Income Insurance Coverage Claims Since the Attacks of Sept. 11, 2001
The 9/11 attacks reshaped business income insurance, spurring decades of litigation over loss calculations, restoration periods, expert evidence, and terrorism coverage. These disputes continue to influence claims and policyholder protections after major catastrophes.
Scientists Uncover a “Pain Switch” That Could Help Ease Arthritis Pain
For years, scientists thought they understood the job of a protein called TRPM2. It sits on the endings of sensory nerves and detects mild, non-painful warmth. That seemed to settle the question of wh...
Jeffries: 'Epstein cover-up in on the ballot'
New York state Sen. Zellnor Myrie says he’s planning on reintroducing legislation that would allow victims of Jeffrey Epstein and other abusers to seek punitive damages from deceased perpetrators’ estates.
After 34 years and 150,000 movies, Scarecrow Video’s longtime buyer retires
Mark Steiner was critical to shaping Scarecrow's video collection, expanding the store's inventory from 1,000 titles in 1992 to more than 156,000 titles today.
Blood proteins may offer new clues to gut health in celiac disease
Celiac disease is an autoimmune condition in which the immune system reacts adversely to gluten. Eating gluten causes inflammation in the gut, which can damage the intestine and impair its ability to ...
Scientists have identified a 'protein signature' in blood that could predict healthy aging
Having a certain ratio of proteins produced by immune cells in your blood is linked to a higher risk of age-related diseases, scientists report.
'Here & Now' Highlights: Charles Franklin, Jason Stein
A month before the 2026 election, the Marquette Law School Poll shows candidates for governor neck-and-neck — poll director Charles Franklin explained where voters stand and why. Enrollment caps for ...
BMW eyes auto division margin of 3-5% in 2028, Bernstein analysts say
BMW set a margin target of 3% to 5% for its auto division in 2028, Bernstein analysts wrote in a note on Wednesday, as the German company plans to offer fewer models and increase localization.
The hidden math of Alzheimer's could point to new treatments
Mathematics may hold unexpected clues to understanding Alzheimer’s disease. Scientists have developed a model showing how common metals like copper and zinc may influence the buildup of proteins associated with the disease, while also exploring possible ways to stop the process. The findings could help researchers identify promising strategies for preventing harmful plaque formation.
Relatives of Epstein victim appear in attack ad targeting Jeff Crank
Relatives of Virginia Giuffre, one of Jeffrey Epstein‘s most prominent victims, accuse U.S. Rep. Jeff Crank in a TV ad released Monday by his Democratic challenger of refusing to meet with them last year when they sought his assistance to force a vote to release federal files related to the convicted sex offender. Sky and […]
Your gut may be making a molecule that raises Alzheimer’s risk
Scientists have linked a gut bacterial compound called ImP to greater Alzheimer’s risk, harmful brain protein buildup, and faster cognitive decline. The finding raises the possibility that reducing ImP in the blood could one day help slow or prevent dementia.
Ghost of Yotei: Complete Edition Gets Awesome Astro Bot, Journey, Helldivers Armour Sets
Ghost with the most
Scientists Find a Hidden Network of Tiny Channels The Brain May Use to Flush Out Toxic Alzheimer's Proteins
Toxic proteins need an exit.
Who gets to be a genius? Matilda effect and the women missing from science
Albert Einstein is probably the most quoted scientist in the world, and among the lines most popularly credited to him is one he almost certainly never said.
Assembly pathway reveals how bacteria build protein coils that extend in acid
The assembly pathway behind refractile-body proteins may have finally been resolved, researchers from Science Tokyo report. Using genetic engineering and several techniques for analyzing protein structure, ...
Starbucks sued over ‘sugar-free’ claims for protein beverages
Starbucks has been sued by consumers who said the coffee chain falsely advertised eight protein beverages as “sugar-free” because they contain lactose, a naturally occurring sugar in milk.
Opinion | Meta Is Crushing Small Online Retailers
Meta is crushing small online businesses by charging more for less effective ads, a sign of its extraordinary grip on the market.
Jared Goldstein, M.D., Joins Baptist Health Urology
September 18, 2026 – Baptist Health is pleased to announce the addition of Jared Goldstein, M.D., a highly skilled urologist and urologic surgeon, to the Baptist Health Urology team. Dr. Goldstein brings to the community extensive expertise in general urology, minimally invasive surgery and men’s health services. Dr. Goldstein specializes in the diagnosis and treatment […]
Eating More Protein Might Not Be as Healthy as You Think
A comprehensive look at scientific research to date points to unexpected benefits from consuming less protein, challenging the surging popularity of protein-packed meals and snacks. The research also raises a bigger question: How much protein do we really need?
Sweet protein brazzein shows promise in reducing blood sugar spikes: Study
Russian research reveals that the protein brazzein could help reduce blood sugar spikes.
Power & Politics: New Charges for former State Sen. Dennis Bradley; one-on-one with Republican candidate for CT's 4th Congressional District
Dr. Don McAulay, of Quinnipiac University, and Republican Congressional Candidate Dr. Michael Goldstein join the show this week.
The Last of Us Day Marked with PS5 Avatars, Ghost of Yotei DLC, Figures
Get your redemption code here
Democrats release midterms ad featuring family of Epstein victim Virginia Giuffre
The campaign arm working to elect House Democrats released a political advertisement on Monday featuring the family of Virginia Giuffre, who was the first victim of Jeffrey Epstein to go public with allegations of abuse.
Matt Vioral Joins Brillstein Entertainment Partners As Manager
Matt Vioral has joined Brillstein Entertainment Partners in a transition to management after two decades at Gersh, Deadline has learned.
ELRIG and The Protein Society announce keynote speakers for Protein Sciences in Drug Discovery 2026
ELRIG, a not-for-profit, volunteer-led organization dedicated to the global drug discovery community, and The Protein Society, an international, not-for-profit, scholarly society, with the mission to provide forums for the advancement of research into protein structure, function, design and applications, today announced the keynote speakers for Protein Sciences in Drug Discovery 2026.