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NMSU computer science undergraduate research experience points students toward Ph.D.
New Mexico State University computer science students were among 120 attending the inaugural in-person workshop and research showcase for the Computing Research Association (CRA) Undergraduate...
Meet Sauqina: ‘My Program Will Really Prepare Me to Upgrade My Skills as a STEM Education Lecturer’
After various roles in the field of science education, Sauqina had the opportunity to help prepare the next generation of science teachers. Now, as a Fulbright Scholar earning her Ph.D. in the Learning and Teaching in STEM science education concentration, she is excited to upgrade her skills and work with other experts in the NC State College of Education.
Social Science: Neither Social nor Science
After finishing required coursework, Ph.D. students in most disciplines take preliminary (sometimes called qualifying) exams to demonstrate that they’re ready to begin independent dissertation…
Scientist whose work revealed immune system-hypertension link to receive the 2026 Joseph A. Vita Award
Embargoed until 8 a.m. CT/9 a.m. ET, Wednesday, Sept. 30, 2026 DALLAS, Sept. 30, 2026 — A groundbreaking scientist whose discoveries revealed how immune activation and inflammation contribute to high blood pressure will be recognized by the American...
Alumni Ronay Bakan Wins Multiple Dissertation Awards from the American Political Science Association
Department of Political Science Ph.D. alumnus Ronay Bakan has won two different awards from sections of the American Political Science Association (APSA) for her dissertation titled “Counterinsurgent Urbanism: Weaponizing Land and Heritage in the Kurdish Region of Turkey”. Bakan won the Best Dissertation Award from the Middle Eastern and North Africa (MENA) section, and Honorable...
Science under siege: As federal funding dries up, top research universities are turning out fewer PhDs
The number of students admitted to Ph.D. programs this fall dropped 15 percent from , according to data from over 50 top research universities, raising
ESMO: Roche touts ‘convincing’ phase 3 KRAS data after win over rivals
Roche has shed more light on its investigational KRAS G12C inhibitor's phase 3 victory over Amgen’s Lumakras and Bristol Myers Squibb’s Krazati. The open-label Krascendo 1 trial enrolled 338 people with previously treated KRAS G12C-mutated non-small cell lung cancer (NSCLC). Patients who had already received a KRAS G12C inhibitor or pan-KRAS/RAS inhibitor were excluded from the trial. Participants received either divarasib once daily, Lumakras once daily or Krazati twice daily. Roche announced back in July that divarasib had demonstrated statistically significant improvements in progression-free survival (PFS) and overall survival (OS), meeting the trial’s primary and key secondary endpoints. But the Swiss pharma had been holding back the detailed data until now. At the European Society for Medical Oncology (ESMO) Congress in Madrid, Roche revealed that median OS for the 167 patients who received divarasib was 17.7 months, compared to 12 months for the 171 patients who received Lumakras or Krazati. The benefit was similarly clear when it came to median PFS, which stood at 9.8 months versus 5.7 months, respectively. A total of 44% of patients receiving divarasib were alive without disease progression at one year, compared to 24% of the control group, according to Roche’s presentation. It was a similar story for the objective response rate, which came in at 58% for divarasib versus 32% for the control group, while median duration of response was 11.9 months versus 6.9 months. Stefan Frings, M.D., Ph.D., deputy chief medical officer at Roche Pharma, told Fierce that the data made for a “very comprehensive, strong package, which should be convincing to health authorities.” “It’s an important advance for patients with lung cancer,” Frings said in an interview at a Madrid hotel during the conference. “It's a second-line setting, and patients who receive divarasib benefit compared to the current first-generation KRAS G12C inhibitors by having far longer overall survival,” he continued. “They live longer. They have better progression-free survival, better response rates, and with a safety profile which is—if [anything]—even better,” he said. According to Roche, 4.8% of patients receiving divarasib discontinued treatment due to treatment-related adverse events, compared to 11.7% in the control group. Serious treatment-related adverse events were also less common with divarasib, at 7.8% versus 15.2%. Roche’s confidence in divarasib had been building even before this phase 3 success. The candidate had already shown better potency and selectivity than the incumbent KRAS G12C inhibitors Krazati and Lumakras in preclinical tests. After cross-trial comparisons suggested that the edge translated into better clinical outcomes, Roche axed a study comparing divarasib to the chemotherapy docetaxel and went toe-to-toe with Lumakras and Krazati. “We designed the drug on purpose with higher potency and better selectivity,” Frings explained. “So, based on preclinical models, we clearly knew it would be superior to the first generation.” “It’s honestly not so frequent that pharma companies go head-to-head,” he added. “But if you want to make a point, if you want to convince payers, prescribers and patients … then a head-to-head win is rather rewarding.” While Amgen and BMS reached the regulatory finish line first for KRAS G12C-mutated, locally advanced or metastatic NSCLC in 2021 and 2022, respectively, they have struggled to capitalize on their head start. Krazati brought in $55 million for BMS in the second quarter, while Lumakras delivered $111 million to Amgen. For its part, Roche is aiming for peak divarasib sales of 1 billion to 2 billion Swiss francs ($1.2 billion to $2.5 billion), according to Frings. The Big Pharma is currently recruiting patients into a phase 3 trial comparing divarasib plus Keytruda against Keytruda plus chemotherapy in previously untreated advanced or metastatic nonsquamous KRAS G12C-mutated NSCLC. Roche has previously suggested that sales in metastatic disease would account for most of the forecast. Frings was tight-lipped on the exact timeline for a regulatory filing but said the Swiss pharma is “certainly keen to get this to as many patients as possible around the world.” Roche has more RAS drugs coming up behind divarasib. The pharma has already launched phase 1 trials of a pan-RAS inhibitor called RG6505 and a KRAS G12D inhibitor dubbed RG6620 in solid tumors. Roche’s partner Chugai Pharmaceutical is also testing a pan-KRAS inhibitor called AUBE00. Roche has made a “deliberate effort” to test a range of RAS drugs, Frings said. “If you have many rare mutations and you are scrambling to find sufficient patients, a pan-RAS inhibitor makes a lot of sense,” he explained.
Optimi Health Appoints Dr. Michael Blough as Chief Clinical Development Officer
Supports Optimi’s planned Phase 2 psilocybin trial in major depressive disorder and Phase 3 MDMA trial in PTSDVANCOUVER, British Columbia, Sept. 22, 2026 (GLOBE NEWSWIRE) -- Optimi Health Corp. (NASDAQ: OPTH) (CSE: OPTI) (FSE: 8BN) ("Optimi" or the "Company"), a commercial-stage pharmaceutical manufacturer of regulated psychedelic drug products, today announced the appointment of Michael Blough, Ph.D., as Chief Clinical Development Officer. Dr. Blough has significant experience leading Health Ca
Cornell science educator David Kornreich, Ph.D. ’01, dies at 52
David Kornreich, Ph.D. ’01, who taught physics and astronomy in the College of Arts and Sciences, died Aug. 30 in a plane crash near Ithaca. Kornreich, a native of Houston, Texas, was 52.
Alumni Ronay Bakan Wins Multiple Dissertation Awards from the American Political Science Association
Department of Political Science Ph.D. alumnus Ronay Bakan has won two different awards from sections of the American Political Science Association (APSA) for her dissertation titled “Counterinsurgent Urbanism: Weaponizing Land and Heritage in the Kurdish Region of Turkey”. Bakan won the Best Dissertation Award from the Middle Eastern and North Africa (MENA) section, and Honorable...
3 Steps to Support Mental Health for Rural Youth
(Feature Impact) Young people face a growing number of pressures, including academic expectations, social responsibilities, complex family situations and uncertainty about their own futures. Mental health support is important for all – but in many rural areas, those pressures are even greater.According to the Centers for Disease Control and Prevention, the suicide rate for rural youth ages 15-19 is 74% higher than their urban counterparts. Barriers like limited insurance coverage, unreliable internet for telehealth, scarce providers, long drive times and lack of public transportation make it harder to get mental healthcare when it’s needed. Plus, asking for help can feel like opening oneself up to judgment and stigmatization.That’s why Rural Minds, the only nonprofit focused on mental health for rural communities, created the Rural Youth Mental Wellness pilot program supported by Boehringer Ingelheim. It was developed by an advisory committee made up of rural youth to provide their peers with practical, free, accessible mental health resources. Incorporating feedback on the pilot, the updated program sponsored by the Sompo Foundation is now launching its national rollout.“A young person’s ZIP code should never determine whether they can access meaningful mental health support where and when they need it,” said Jessica L. Schleider, Ph.D., director, Lab for Scalable Mental Health, Northwestern University. “Our lab is thrilled to partner with Rural Minds as they champion evidence-based, anonymous, freely available support tools designed to overcome barriers to help-seeking faced by rural youth across the country.”If the rural mental health crisis affects you or a loved one, consider these ways to help.Break the Stigma Surrounding Mental HealthIn communities where self-reliance is valued, asking for help can sometimes be viewed as a sign of weakness. Young people who feel unheard and unsupported often struggle with being vulnerable, so they continue carrying their increasingly heavy burdens alone.Parents, educators, healthcare providers, community leaders and peers can work to change that culture by normalizing mental health conversations. This includes helping teenagers feel seen and accepted by educating them on mental health issues and coping strategies, listening to their experiences without judgment, sharing your own stories and reminding them it’s courageous to seek support.Consider Single-Session InterventionsThe first step is always the hardest when it comes to seeking mental health support, and not every struggling young person is ready or able to see a therapist. With access to free, confidential, self-guided materials to begin building mental wellness skills, the first step may be less scary.Single-Session Interventions (SSIs) are brief, structured online courses designed to teach youth practical skills for handling stress, low mood, self-image and more. The Rural Youth Mental Wellness Program offers SSIs in partnership with Project YES (Youth Empowerment and Support), a free digital resource developed with Northwestern University’s Lab for Scalable Mental Health at the Feinberg School of Medicine.Anonymous access to SSIs through the partnership provides strategies for:Improving moodRethinking body imageReframing negative thoughtsKnowing your power to changeTaking steps toward goalsProtecting LGBTQ+ prideHandling self-harm urgesStaying safe amid dark thoughtsEach SSI typically takes 5-10 minutes. Although SSIs are not a replacement for therapy, they provide a research-backed source of support for young people experiencing bouts of stress or low-to-moderate distress.Know When to Seek Professional HelpSelf-guided resources and supportive conversations are a valuable starting point, but sometimes young people need qualified professional help. Look for symptoms like worsening mood or behavior, substance use, self-harm or difficulty managing everyday tasks, and take teens seriously when they express dark feelings.Doctors and counselors can provide personalized support for youth in crisis, and the 988 Suicide and Crisis Lifeline offers free, confidential 24/7 support for mental health by dialing 9-8-8.“I grew up in a small town where mental health was almost taboo,” said committee member Asheton Medlin. “Being part of the committee that built this program let me help make sure rural youth today have the support I didn’t. I’m excited to help bring these resources to them because this generation deserves the chance to grow up and change the world.”Find more information at RuralMinds.org.Photos courtesy of Shutterstock googletag.cmd.push(function() { googletag.display('yup-rectangle-one'); });
AAPS names Patrick Sinko chief science officer
The American Association of Pharmaceutical Scientists (AAPS) has named Patrick J. Sinko, Ph.D., R.Ph., as chief science officer. Sinko will set the organization’s scientific strategy, guide scientific programming across in-person and digital platforms, and guide the direction of AAPS’s portfolio of peer-reviewed journals. Sinko, a pharmacist and pharmaceutical scientist, retains his academic appointment at Rutgers,…
Rear Admiral Tim Gallaudet, PhD, USN (Ret.) to Discuss “Marine Science & Technology Leadership in Turbulent Times” at St. Mary’s College
The Patuxent Partnership and the Steny H. Hoyer Center for the Study of Democracy at St. Mary’s College of Maryland will present an evening with Rear Admiral. Tim Gallaudet, Ph.D., USN (Ret.), on Wednesday, Sept. 30, from 5-7 p.m. at the College’s Nancy R. and Norton T. Dodge Performing Arts Center.
Computational Models as Liminal Models in Neuroscience, a Cognitive Science Speaker Series Presentation | Events
Speaker: Danielle Williams, Ph.D. Title: Computational Models as Liminal Models in Neuroscience Short Bio: Danielle is a philosopher of mind and science whose research examines the role of computation in our theories and explanations of the mind and brain. Her work brings together philosophy of mind, cognitive science, neuroscience, and artificial intelligence, with particular interests in computational theories of mind, computational modeling, and the relationship between different explanatory and modeling strategies in the mind sciences. She also investigates philosophical questions raised by contemporary AI, including the nature of opacity in computational models and its implications for explanation in cognitive science. Alongside this work, she is a historian of cognitive science and AI, examining how the development of computer technology has shaped our conceptions and models of the mind and brain. Abstract: Scientists rely on various types of models to make sense of their phenomena of interest. This has led philosophers to take up a range of semantic, ontological, and epistemological questions about how models represent, what kinds of things models are, what we learn from models, and how they explain. One type of model that has been of particular interest to philosophers is the computational model. Computational models are commonplace in the mind sciences in general and neuroscience in particular, with many asking how computational modeling can help us understand the nervous system and its contribution to cognition and behavior. These questions are particularly pressing in neuroscience, as computational models have become a dominant framework for making sense of cognition. Thus, old questions about model-based science have re-emerged within the context of neuroscience, with many philosophers looking to established frameworks to understand how computational models represent, explain, and contribute to theory development in neuroscience. These established frameworks, however, characterize computational models as a homogeneous type which cannot capture actual modeling practices in neuroscience. In this talk, I argue that computational models in neuroscience are best typed as a kind of liminal model, a type I introduce to capture how the status of a computational model is determined by the epistemic context in which it is deployed. Indeed, the category to which a computational model belongs shifts according to the role it plays within a given context. ASL-English interpreters have been requested. Light refreshments will be provided.
Food science student finds a sweeter path to her Ph.D.
Julia Adornetto found her calling in the science of sensory evaluation, overcoming setbacks with the help of faculty mentors and scholarships.
Johns Hopkins Researchers’ Cancer Cell Mapping Technology Chosen for Anthropic AI for Science Project
Johns Hopkins University astrophysicist Alexander Szalay, Ph.D., and Johns Hopkins Medicine Department of Dermatology and Sidney Kimmel Comprehensive Cancer Center pathologist Janis Taube, M.D., M.Sc., were chosen for a research project in Anthropic's AI for Science program. They were selected for their pioneering AstroPath technology, which combines astronomy, pathology and artificial intelligence (AI) to create detailed maps of tumors, revealing how cancer cells interact with surrounding cells
Mars Has Its Charmes
Written by Athanasios (Thanos) Klidaras, Ph.D. candidate at Purdue University
Visa time limits on foreign Ph.D. students and postdocs will harm U.S. science, experts warn
A Trump administration plan to limit visas for graduate student and postdocs to four years is fueling concerns that the U.S. could lose out on foreign scientists
Texas Tech University Health Sciences Center Appoints New Graduate School of Biomedical Sciences Dean and Vice Dean
TTUHSC has named Lance R. McMahon, Ph.D., as the new Graduate School of Biomedical Sciences dean and Kendra P. Rumbaugh, Ph.D., as vice dean.
A woman on a mission
Mindy Engevik, Ph.D., is a woman on a mission. Make that TWO missions. Her vocation is studying the interaction between gut microbes and the gastrointestinal tract. Her avocation is advancing the careers of young women in science. She’s passionate about both goals, and she’s recently earned two prestigious national awards recognizing her achievements.
UCO Reaches Historic Milestone to Unleash Student and State Workforce Opportunities with Approval of First Ph.D.
The University of Central Oklahoma expands its academic impact with approval of its first-ever Ph.D. program. This achievement is a significant milestone in UCO's 136-year history.
A Journey to the Depths of Ancient Mars?
Written by Alex Jones, Ph.D. candidate at Imperial College London
NSF testing new Ph.D. model giving trainees academic and industry experience
Young life scientists have been increasingly abandoning academia, a seismic shift that has fueled calls for rethinking graduate education. On Wednesday,
Reappointment of Senior Vice Chancellor of UCLA Health Sciences John Mazziotta - UCLA Office of the Chancellor
Chancellor Julio Frenk shared this message with faculty and staff. Dear Colleagues: I am pleased to announce that John Mazziotta, M.D., Ph.D., has been reappointed for a five-year term and will now serve as senior vice chancellor of UCLA Health...
AgriLife Research scientist receives international Borlaug early career award
Shannon Baker, Ph.D., Texas A&M AgriLife Research, received the 2026 Jeanie Borlaug Laube Women in Triticum, WIT, Early Career Awards.
Diego Martinez joins Texas A&M Department of Poultry Science
Diego A. Martinez, Ph.D., joined the Texas A&M Department of Poultry Science in the College of Agriculture and Life Sciences as an assistant professor of poultry nutrition on August 1.
3 Steps to Support Mental Health for Rural Youth
(Feature Impact) Young people face a growing number of pressures, including academic expectations, social responsibilities, complex family situations and uncertainty about their own futures. Mental health support is important for all – but in many rural areas, those pressures are even greater.According to the Centers for Disease Control and Prevention, the suicide rate for rural youth ages 15-19 is 74% higher than their urban counterparts. Barriers like limited insurance coverage, unreliable internet for telehealth, scarce providers, long drive times and lack of public transportation make it harder to get mental healthcare when it’s needed. Plus, asking for help can feel like opening oneself up to judgment and stigmatization.That’s why Rural Minds, the only nonprofit focused on mental health for rural communities, created the Rural Youth Mental Wellness pilot program supported by Boehringer Ingelheim. It was developed by an advisory committee made up of rural youth to provide their peers with practical, free, accessible mental health resources. Incorporating feedback on the pilot, the updated program sponsored by the Sompo Foundation is now launching its national rollout.“A young person’s ZIP code should never determine whether they can access meaningful mental health support where and when they need it,” said Jessica L. Schleider, Ph.D., director, Lab for Scalable Mental Health, Northwestern University. “Our lab is thrilled to partner with Rural Minds as they champion evidence-based, anonymous, freely available support tools designed to overcome barriers to help-seeking faced by rural youth across the country.”If the rural mental health crisis affects you or a loved one, consider these ways to help.Break the Stigma Surrounding Mental HealthIn communities where self-reliance is valued, asking for help can sometimes be viewed as a sign of weakness. Young people who feel unheard and unsupported often struggle with being vulnerable, so they continue carrying their increasingly heavy burdens alone.Parents, educators, healthcare providers, community leaders and peers can work to change that culture by normalizing mental health conversations. This includes helping teenagers feel seen and accepted by educating them on mental health issues and coping strategies, listening to their experiences without judgment, sharing your own stories and reminding them it’s courageous to seek support.Consider Single-Session InterventionsThe first step is always the hardest when it comes to seeking mental health support, and not every struggling young person is ready or able to see a therapist. With access to free, confidential, self-guided materials to begin building mental wellness skills, the first step may be less scary.#placement_1042740_0_i{width:100%;max-width:550px;margin:0 auto;}var rnd = window.rnd || Math.floor(Math.random()*10e6);var pid1042740 = window.pid1042740 || rnd;var plc1042740 = window.plc1042740 || 0;var abkw = window.abkw || '';var absrc = 'https://ads.empowerlocal.co/adserve/;ID=181918;size=0x0;setID=1042740;type=js;sw='+screen.width+';sh='+screen.height+';spr='+window.devicePixelRatio+';kw='+abkw+';pid='+pid1042740+';place='+(plc1042740++)+';rnd='+rnd+';click=CLICK_MACRO_PLACEHOLDER';var _absrc = absrc.split("type=js"); absrc = _absrc[0] + 'type=js;referrer=' + encodeURIComponent(document.location.href) + _absrc[1];document.write('');Single-Session Interventions (SSIs) are brief, structured online courses designed to teach youth practical skills for handling stress, low mood, self-image and more. The Rural Youth Mental Wellness Program offers SSIs in partnership with Project YES (Youth Empowerment and Support), a free digital resource developed with Northwestern University’s Lab for Scalable Mental Health at the Feinberg School of Medicine.Anonymous access to SSIs through the partnership provides strategies for:Improving moodRethinking body imageReframing negative thoughtsKnowing your power to changeTaking steps toward goalsProtecting LGBTQ+ prideHandling self-harm urgesStaying safe amid dark thoughtsEach SSI typically takes 5-10 minutes. Although SSIs are not a replacement for therapy, they provide a research-backed source of support for young people experiencing bouts of stress or low-to-moderate distress.Know When to Seek Professional HelpSelf-guided resources and supportive conversations are a valuable starting point, but sometimes young people need qualified professional help. Look for symptoms like worsening mood or behavior, substance use, self-harm or difficulty managing everyday tasks, and take teens seriously when they express dark feelings.Doctors and counselors can provide personalized support for youth in crisis, and the 988 Suicide and Crisis Lifeline offers free, confidential 24/7 support for mental health by dialing 9-8-8.“I grew up in a small town where mental health was almost taboo,” said committee member Asheton Medlin. “Being part of the committee that built this program let me help make sure rural youth today have the support I didn’t. I’m excited to help bring these resources to them because this generation deserves the chance to grow up and change the world.”Find more information at RuralMinds.org.Photos courtesy of Shutterstock
3 Steps to Support Mental Health for Rural Youth
(Feature Impact) Young people face a growing number of pressures, including academic expectations, social responsibilities, complex family situations and uncertainty about their own futures. Mental health support is important for all – but in many rural areas, those pressures are even greater.According to the Centers for Disease Control and Prevention, the suicide rate for rural youth ages 15-19 is 74% higher than their urban counterparts. Barriers like limited insurance coverage, unreliable internet for telehealth, scarce providers, long drive times and lack of public transportation make it harder to get mental healthcare when it’s needed. Plus, asking for help can feel like opening oneself up to judgment and stigmatization.That’s why Rural Minds, the only nonprofit focused on mental health for rural communities, created the Rural Youth Mental Wellness pilot program supported by Boehringer Ingelheim. It was developed by an advisory committee made up of rural youth to provide their peers with practical, free, accessible mental health resources. Incorporating feedback on the pilot, the updated program sponsored by the Sompo Foundation is now launching its national rollout.“A young person’s ZIP code should never determine whether they can access meaningful mental health support where and when they need it,” said Jessica L. Schleider, Ph.D., director, Lab for Scalable Mental Health, Northwestern University. “Our lab is thrilled to partner with Rural Minds as they champion evidence-based, anonymous, freely available support tools designed to overcome barriers to help-seeking faced by rural youth across the country.”If the rural mental health crisis affects you or a loved one, consider these ways to help.Break the Stigma Surrounding Mental HealthIn communities where self-reliance is valued, asking for help can sometimes be viewed as a sign of weakness. Young people who feel unheard and unsupported often struggle with being vulnerable, so they continue carrying their increasingly heavy burdens alone.Parents, educators, healthcare providers, community leaders and peers can work to change that culture by normalizing mental health conversations. This includes helping teenagers feel seen and accepted by educating them on mental health issues and coping strategies, listening to their experiences without judgment, sharing your own stories and reminding them it’s courageous to seek support.Consider Single-Session InterventionsThe first step is always the hardest when it comes to seeking mental health support, and not every struggling young person is ready or able to see a therapist. With access to free, confidential, self-guided materials to begin building mental wellness skills, the first step may be less scary.Single-Session Interventions (SSIs) are brief, structured online courses designed to teach youth practical skills for handling stress, low mood, self-image and more. The Rural Youth Mental Wellness Program offers SSIs in partnership with Project YES (Youth Empowerment and Support), a free digital resource developed with Northwestern University’s Lab for Scalable Mental Health at the Feinberg School of Medicine.Anonymous access to SSIs through the partnership provides strategies for:Improving moodRethinking body imageReframing negative thoughtsKnowing your power to changeTaking steps toward goalsProtecting LGBTQ+ prideHandling self-harm urgesStaying safe amid dark thoughtsEach SSI typically takes 5-10 minutes. Although SSIs are not a replacement for therapy, they provide a research-backed source of support for young people experiencing bouts of stress or low-to-moderate distress.Know When to Seek Professional HelpSelf-guided resources and supportive conversations are a valuable starting point, but sometimes young people need qualified professional help. Look for symptoms like worsening mood or behavior, substance use, self-harm or difficulty managing everyday tasks, and take teens seriously when they express dark feelings.Doctors and counselors can provide personalized support for youth in crisis, and the 988 Suicide and Crisis Lifeline offers free, confidential 24/7 support for mental health by dialing 9-8-8.“I grew up in a small town where mental health was almost taboo,” said committee member Asheton Medlin. “Being part of the committee that built this program let me help make sure rural youth today have the support I didn’t. I’m excited to help bring these resources to them because this generation deserves the chance to grow up and change the world.”Find more information at RuralMinds.org.Photos courtesy of Shutterstock
Business Profile: Hopkinton Psychological Services offers therapy, scientific-based treatments
Combining treatments based on research with a relaxed, conversational psychotherapy, Keith Donohue, Ph.D., helps clients address a variety of mental
Dean Simon Sheather to retire after transformative tenure at UK Gatton College of Business and Economics
After more than three decades in higher education — and nearly eight years of transformative leadership at the University of Kentucky — Simon Sheather, Ph.D., will retire as dean of the Gatton College of Business and Economics, effective June 26.
3 Steps to Support Mental Health for Rural Youth
(Feature Impact) Young people face a growing number of pressures, including academic expectations, social responsibilities, complex family situations and uncertainty about their own futures. Mental health support is important for all – but in many rural areas, those pressures are even greater.#placement_1126603_0_i{width:100%;max-width:550px;margin:0 auto;}var rnd = window.rnd || Math.floor(Math.random()*10e6);var pid1126603 = window.pid1126603 || rnd;var plc1126603 = window.plc1126603 || 0;var abkw = window.abkw || '';var absrc = 'https://ads.empowerlocal.co/adserve/;ID=181918;size=0x0;setID=1126603;type=js;sw='+screen.width+';sh='+screen.height+';spr='+window.devicePixelRatio+';kw='+abkw+';pid='+pid1126603+';place='+(plc1126603++)+';rnd='+rnd+';click=CLICK_MACRO_PLACEHOLDER';var _absrc = absrc.split("type=js"); absrc = _absrc[0] + 'type=js;referrer=' + encodeURIComponent(document.location.href) + _absrc[1];document.write('');According to the Centers for Disease Control and Prevention, the suicide rate for rural youth ages 15-19 is 74% higher than their urban counterparts. Barriers like limited insurance coverage, unreliable internet for telehealth, scarce providers, long drive times and lack of public transportation make it harder to get mental healthcare when it’s needed. Plus, asking for help can feel like opening oneself up to judgment and stigmatization.That’s why Rural Minds, the only nonprofit focused on mental health for rural communities, created the Rural Youth Mental Wellness pilot program supported by Boehringer Ingelheim. It was developed by an advisory committee made up of rural youth to provide their peers with practical, free, accessible mental health resources. Incorporating feedback on the pilot, the updated program sponsored by the Sompo Foundation is now launching its national rollout.“A young person’s ZIP code should never determine whether they can access meaningful mental health support where and when they need it,” said Jessica L. Schleider, Ph.D., director, Lab for Scalable Mental Health, Northwestern University. “Our lab is thrilled to partner with Rural Minds as they champion evidence-based, anonymous, freely available support tools designed to overcome barriers to help-seeking faced by rural youth across the country.”If the rural mental health crisis affects you or a loved one, consider these ways to help.Break the Stigma Surrounding Mental HealthIn communities where self-reliance is valued, asking for help can sometimes be viewed as a sign of weakness. Young people who feel unheard and unsupported often struggle with being vulnerable, so they continue carrying their increasingly heavy burdens alone.Parents, educators, healthcare providers, community leaders and peers can work to change that culture by normalizing mental health conversations. This includes helping teenagers feel seen and accepted by educating them on mental health issues and coping strategies, listening to their experiences without judgment, sharing your own stories and reminding them it’s courageous to seek support.Consider Single-Session InterventionsThe first step is always the hardest when it comes to seeking mental health support, and not every struggling young person is ready or able to see a therapist. With access to free, confidential, self-guided materials to begin building mental wellness skills, the first step may be less scary. Single-Session Interventions (SSIs) are brief, structured online courses designed to teach youth practical skills for handling stress, low mood, self-image and more. The Rural Youth Mental Wellness Program offers SSIs in partnership with Project YES (Youth Empowerment and Support), a free digital resource developed with Northwestern University’s Lab for Scalable Mental Health at the Feinberg School of Medicine.Anonymous access to SSIs through the partnership provides strategies for:Improving moodRethinking body imageReframing negative thoughtsKnowing your power to changeTaking steps toward goalsProtecting LGBTQ+ prideHandling self-harm urgesStaying safe amid dark thoughtsEach SSI typically takes 5-10 minutes. Although SSIs are not a replacement for therapy, they provide a research-backed source of support for young people experiencing bouts of stress or low-to-moderate distress.Know When to Seek Professional HelpSelf-guided resources and supportive conversations are a valuable starting point, but sometimes young people need qualified professional help. Look for symptoms like worsening mood or behavior, substance use, self-harm or difficulty managing everyday tasks, and take teens seriously when they express dark feelings.Doctors and counselors can provide personalized support for youth in crisis, and the 988 Suicide and Crisis Lifeline offers free, confidential 24/7 support for mental health by dialing 9-8-8.“I grew up in a small town where mental health was almost taboo,” said committee member Asheton Medlin. “Being part of the committee that built this program let me help make sure rural youth today have the support I didn’t. I’m excited to help bring these resources to them because this generation deserves the chance to grow up and change the world.”Find more information at RuralMinds.org.Photos courtesy of Shutterstock
BioMarin appoints Robert Plenge to its Board and Science & Technology Committee
BioMarin appointed Robert Plenge, M.D., Ph.D., to its Board of Directors and to the Science and Technology Committee, effective September 10, 2026.Original SEC Filing: BIOMARIN PHARMACEUTICAL INC [ BMRN ] - 8-K - Sep. 14, 2026This is an AI-powered summary. It may contain inaccuracies. Consider veri…
Cancer drug tames atherosclerosis inflammation and plaque in animal models
A new Yale study has identified a promising therapeutic avenue for atherosclerosis, a condition caused by inflammation and plaque buildup in arteries. Martin Schwartz, Ph.D., Robert W. Berliner Professor ...
Nithya Rajan’s journey from the field to the forefront of crop science
Nithya Rajan, Ph.D., Texas A&M AgriLife agronomist and cropping system researcher, developed a producer-outcome perspective for soil science.
URI to launch new computational social science doctoral program
KINGSTON, R.I. – Oct. 1, 2026 – The University of Rhode Island is introducing a new Computational Social Science Ph.D. program, citing a growing demand for trained social scientists who can ethically use advanced computational methods to study complex social problems and inform evidence-based decisions. Set to launch in the fall of 2027, URI’s new […]
Eberly, Fox Graduate School to celebrate 100 years of the Penn State Ph.D. on Oct. 2
Join the Eberly College of Science, Department of Physics, and the J. Jeffrey and Ann Marie Fox Graduate School from 3 to 4 p.m. on Friday, Oct. 2, in 117 Osmond Building or via webinar to celebrate 100 years of doctoral degrees at Penn State.
New Science Ph.D. Program Saves Time and Money
A new program offers an alternative to the standard academic Ph.D. in science, and this competition will prove beneficial.
3 Steps to Support Mental Health for Rural Youth
(Feature Impact) Young people face a growing number of pressures, including academic expectations, social responsibilities, complex family situations and uncertainty about their own futures. Mental health support is important for all – but in many rural areas, those pressures are even greater. TNCMS.AdManager.render({region: 'fixed-big-ad-top-asset', slot: 1, fold: "above"}); According to the Centers for Disease Control and Prevention, the suicide rate for rural youth ages 15-19 is 74% higher than their urban counterparts. Barriers like limited insurance coverage, unreliable internet for telehealth, scarce providers, long drive times and lack of public transportation make it harder to get mental healthcare when it’s needed. Plus, asking for help can feel like opening oneself up to judgment and stigmatization.That’s why Rural Minds, the only nonprofit focused on mental health for rural communities, created the Rural Youth Mental Wellness pilot program supported by Boehringer Ingelheim. It was developed by an advisory committee made up of rural youth to provide their peers with practical, free, accessible mental health resources. Incorporating feedback on the pilot, the updated program sponsored by the Sompo Foundation is now launching its national rollout.“A young person’s ZIP code should never determine whether they can access meaningful mental health support where and when they need it,” said Jessica L. Schleider, Ph.D., director, Lab for Scalable Mental Health, Northwestern University. “Our lab is thrilled to partner with Rural Minds as they champion evidence-based, anonymous, freely available support tools designed to overcome barriers to help-seeking faced by rural youth across the country.”If the rural mental health crisis affects you or a loved one, consider these ways to help.Break the Stigma Surrounding Mental HealthIn communities where self-reliance is valued, asking for help can sometimes be viewed as a sign of weakness. Young people who feel unheard and unsupported often struggle with being vulnerable, so they continue carrying their increasingly heavy burdens alone.Parents, educators, healthcare providers, community leaders and peers can work to change that culture by normalizing mental health conversations. This includes helping teenagers feel seen and accepted by educating them on mental health issues and coping strategies, listening to their experiences without judgment, sharing your own stories and reminding them it’s courageous to seek support.Consider Single-Session InterventionsThe first step is always the hardest when it comes to seeking mental health support, and not every struggling young person is ready or able to see a therapist. With access to free, confidential, self-guided materials to begin building mental wellness skills, the first step may be less scary. TNCMS.AdManager.render({region: 'fixed-big-ad-middle-asset', slot: 1, fold: "span"}); Single-Session Interventions (SSIs) are brief, structured online courses designed to teach youth practical skills for handling stress, low mood, self-image and more. The Rural Youth Mental Wellness Program offers SSIs in partnership with Project YES (Youth Empowerment and Support), a free digital resource developed with Northwestern University’s Lab for Scalable Mental Health at the Feinberg School of Medicine.Anonymous access to SSIs through the partnership provides strategies for:Improving moodRethinking body imageReframing negative thoughtsKnowing your power to changeTaking steps toward goalsProtecting LGBTQ+ prideHandling self-harm urgesStaying safe amid dark thoughtsEach SSI typically takes 5-10 minutes. Although SSIs are not a replacement for therapy, they provide a research-backed source of support for young people experiencing bouts of stress or low-to-moderate distress.Know When to Seek Professional HelpSelf-guided resources and supportive conversations are a valuable starting point, but sometimes young people need qualified professional help. Look for symptoms like worsening mood or behavior, substance use, self-harm or difficulty managing everyday tasks, and take teens seriously when they express dark feelings.Doctors and counselors can provide personalized support for youth in crisis, and the 988 Suicide and Crisis Lifeline offers free, confidential 24/7 support for mental health by dialing 9-8-8.“I grew up in a small town where mental health was almost taboo,” said committee member Asheton Medlin. “Being part of the committee that built this program let me help make sure rural youth today have the support I didn’t. I’m excited to help bring these resources to them because this generation deserves the chance to grow up and change the world.”Find more information at RuralMinds.org.Photos courtesy of Shutterstock TNCMS.AdManager.render({region: 'fixed-big-ad-bottom-asset', slot: 1, fold: "below"});
The startup idea that convinced a UW computer science legend to leave Google after 27 years
Jeff Dean, who earned his computer science Ph.D. at the University of Washington, is leaving Google after 27 years and taking three of the company's top AI researchers with him. Their startup, Discovery Loop, aims to automate the scientific method itself, and Google is helping fund it.
Science, Public Health, and the Politics of Truth
Presented as part of the McCloskey Speaker Series.Peter Hotez, M.D., Ph.D., professor and dean of the National School of Tropical Medicine at Baylor College of Medicine, joins the Aspen Institute for a keynote lecture on the intersection of science, medicine, and public trust. A leading authority on vaccines and neglected tropical diseases, Hotez reflects on the challenges facing public health today, the growing politicization of science, and what it will take to rebuild trust in scientific institutions in the years ahead.Paepcke Auditorium, doors at 5:00 pmRegistrationThis event is free and open to the public, but registration is required, and capacity is established on a first-come, first-served basis. Once an event is at capacity, we will have an in-person waitlist at the door.Public registration is now open for summer 2026. Please click here to register.ParkingParking is very limited. Please carpool, walk, bike, or ride RFTA.Book signing will immediately follow the event. To learn more about his book or to order a copy, please click here.
L7 Informatics Names Ray Veeraraghavan, Ph.D., Vice President of Science and AI
/PRNewswire/ -- L7 Informatics, Inc., the company behind L7|ESP®, the Enterprise Science Platform that serves as an operating system for precision science,...
Rial-Faigenbaum Helps Advance New Strength–Risk Continuum in Sports Medicine
Tamara Rial-Faigenbaum, Ph.D., specialist professor in the Department of Health and Physical Education, is a co-author in the British Journal of Sports Medicine editorial calling for muscular weakness to be recognized as a clinically relevant risk marker and for muscle strength to become a routine component of health care. The article “The Strength-Risk Continuum: Reframing […]
Brooklyn College Names New Dean for the Murray Koppelman School of Business
Shalei V. K. Simms, Ph.D., appointed to lead Brooklyn’s only AACSB-accredited business school.
Neil Garg named recipient of the 2026 Science and Education Pioneer Award
Distinguished Professor Neil Garg has been named the recipient of the UCLA College, Division of Physical Sciences’ 2026 Science and Education Pioneer Award for his contributions to science and education. He will be honored at Exploring Your Universe, UCLA’s free science festival, on Sunday, Nov. 8, in the Court of Sciences. The ceremony and Garg’s remarks will take place at noon in Young Hall CS50, and will be livestreamed here. He will also give a family-friendly lecture, “Organic Chemistry in the Movies”, at 3 pm in Young Hall CS76. The Pioneer Award recognizes individuals who have made significant contributions to science and inspired public engagement with science education, particularly among young people. Previous award recipients include astronaut and UCLA alumna Dr. Anna Lee Fisher (2017), mathematician and UCLA alumna Danica McKellar (2018), actress, author and neuroscientist Dr. Mayim Bialik (2019), Nobel Prize-winning astrophysicist Andrea Ghez (2020) and UCLA mathematics professor and Fields Medalist Terence Tao (2025). Garg is the Distinguished Kenneth N. Trueblood Professor of Chemistry and Biochemistry at UCLA. He received his B.S. from New York University and Ph.D. from Caltech, and completed postdoctoral studies at UC Irvine before joining the UCLA faculty in 2007. Garg is an internationally recognized organic chemist whose research focuses on developing new chemical reactions, often challenging long-standing rules in chemistry. He has published more than 200 scientific papers. Beyond his research accomplishments and award-winning classroom teaching, Garg is passionate about making chemistry accessible and engaging for students and the broader public. He has developed innovative websites, apps, and games used in more than 175 countries, authored The Organic Coloring Book series, and created outreach programs that introduce children to chemistry, including his popular Chem Kids camp. His honors include the Royal Society of Chemistry’s Horizon Prizes for both research and education, the Cherry Award for Great Teaching, the California Professor of the Year Award, and the AAAS Mani L. Bhaumik Award for Public Engagement with Science. In 2026, he received the Royal Society of Chemistry’s prestigious Centenary Prize.
2026-2027 Audree V. Fowler Fellows in Protein Science
Graduate students Lenka Milojević (Zhou group), Akshaya Narayanasamy (Lindert group), Sarah Singleton (Conway group), and Janet Zhong (Feigon group) have been selected as 2026–27 Fowler Fellows and shared their research at a special event on Oct. 13, 2026. 2026-27 Fowler Fellows – Sarah Singleton, Lenka Milojević, Janet Zhong, and Akshaya Narayanasamy. Akshaya Narayanasamy and Prof. Steffen Lindert. Sarah Singleton and Prof. Stuart Conway. Janet Zhong and Prof. Juli Feigon. About the 2026-27 Audree Fowler Fellows in Protein Science Lenka Milojević is a fifth-year Biophysics Ph.D. candidate in the lab of Professor Z. Hong Zhou at UCLA. As an undergraduate at Maastricht University, she studied the structural basis of Mycobacterium tuberculosis virulence and amyloid-β fibril nucleation in the lab of Professor Peter Peters. She completed her bachelor’s thesis research at UCLA in the lab of Professor David Eisenberg, focusing on amyloid disaggregation, before beginning her doctoral studies. In the Zhou lab, Lenka uses cryo-electron tomography to visualize and characterize membrane-associated protein assemblies across a range of viral and cellular systems. Akshaya Narayanasamy is a fifth-year Ph.D. student in the Department of Chemistry and Biochemistry at UCLA, mentored by Professor Steffen Lindert. She earned her B.S.-M.S. in Chemistry from the Indian Institute of Science Education and Research, Thiruvananthapuram, where she worked in Professor Mahesh Hariharan’s lab investigating how single-atom substitutions influence crystal packing and charge transport behavior. She received her M.S. in Physical Chemistry from The Ohio State University before moving with the Lindert lab to UCLA. At UCLA, Akshaya develops integrative modeling methods that combine deep learning and Rosetta with experimental data, such as ion mobility mass spectrometry and cryo-EM, to improve protein structure prediction. Her current work focuses on developing an experimentally guided diffusion model and designing de novo protein binders with potential antibacterial activity. Ultimately, she aims to bridge AI-based structure prediction and experimental data to make computational protein models more reliable for drug discovery and therapeutic design. Sarah Singleton is a 4th year BMSB student, working in Professor Stuart Conway’s lab. She earned her B.S. in Biochemistry at Simmon University (Fenway, MA). Her research is centered on drugging the previously undruggable class of proteins—transcription factors. Zinc finger (ZF)-containing transcription factor proteins typically contain multiple ZF motifs, but little is known about the principles that govern the recognition of multi-ZF arrays by immunomodulatory imide drugs (IMiDs). In a multi-ZF array that contains several potentially targetable ZFs, which will be accessible and why? How does the surrounding protein architecture inform IMiD recognition? Sarah’s research aims to utilize her findings on the fundamental principles of ZF recognition to design IMiD therapeutics for transcription factors involved in health and disease. Janet Zhong is a fourth-year BMSB student, working in Professor Juli Feigon’s laboratory. She received her BSc and MRes from Imperial College London. At UCLA, Janet combines cryo-electron microscopy (cryo-EM) and biochemical approaches to investigate how proteins and RNAs assemble into ribonucleoprotein structures. Her research focuses on telomerase, the enzyme that maintains chromosome ends, with interests in its structure, assembly, and mechanisms. She has also worked on capturing the cryo-EM structure of a small bacterial non-coding RNA called raiA motif RNA. About Dr. Audree Fowler A strong supporter of the basic sciences and medicine at UCLA, alumna Dr. Audree Fowler (B.S. ’56 chemistry, Ph.D. ’63 biochemistry) established the Audree V. Fowler Fellows in Protein Science in 2008. Fowler was Director UCLA Protein Microsequencing Facility from 1984-1999 and is a Researcher Emeritus of the UCLA Department of Biological Chemistry. She is one of the first four women to receive a Ph.D. from the UCLA Department of Chemistry & Biochemistry. In 2018, the women were awarded the department’s 2018 Alumni Legacy Awards in recognition of their achievements in life, and generous support and service to UCLA. “The sciences gave me a great life. Now I want to help others have access to the same opportunities I enjoyed,” Fowler explained when she established the Fowler Fellowships endowment. Applications for the fellowships are solicited from graduate students in the Molecular Biology Interdepartmental (MBI) Ph.D. Program, Biological Chemistry, and Chemistry & Biochemistry Departments. In addition to presenting their research at a special seminar, the recipients each receive a $5,000 award. Previous Fowler Fellows from the UCLA Department of Chemistry & Biochemistry 2025-26 – Nikki Cheung (Clubb Group), Jonathan Jih (Zhou Group), Eileen Olivares (Loo Group), and Lily Taylor (Rodriguez Group) 2024-25 – Andrew Goring (Clubb lab), Eric Pang (S. Clarke and Rodriguez labs), and Miranda Villanueva (Backus lab) 2023-24 – Alexandra Turmon (Backus lab), Cindy Wang (S. Clarke and C. Clarke labs) 2022-23 – Cody Gillman (Gonen lab), Declan Evans (Houk lab), Troy Lowe (S. Clarke lab), Ashley Julio (Backus lab), and Alex Stevens (Hong Zhou lab) 2021-22 – Weixian Deng (Wohlschlegel/Plath labs), Yi Xiao “Sean” Jiang (Eisenberg lab), Maria Flores (Rodriguez lab), Carter Lantz (Loo lab), and Logan Richards (Rodriguez lab). 2020-21 – Janine Fu (Loo lab), Calina Glynn (Rodriguez lab), and Jiahui Lu (Eisenberg lab) 2019-20 – David Boyer (Eisenberg lab), Orlando Martinez (Clubb lab) and John Muroski (Loo lab) 2018-19 – Scott McConnell (Clubb lab), Kevin Murray (Eisenberg lab), Rebeccah Warmack (S. Clarke lab) 2017-18 – Michael Hughes (Eisenberg lab), Yuxi Liu (Yeates lab), Kanishk Jain (S. Clarke lab) 2016-17 – Brendan Amer (Clubb Lab) and Jeff Vinokur (Bowie Lab) 2015-16 – Henry Chan (Feigon lab), Smriti Sangwan (Eisenberg lab), Nicholas Woodall (Bowie lab) 2014-15 – Dan McNamara (Yeates lab) 2013-14 – Alex Jacobitz (Clubb lab), Alexander Patananan (S. Clarke lab), Carly Ferguson (Loo lab) 2012-13 – Letian Xie (C. Clarke lab), Anni Zhao (Eisenberg lab) 2011-12 – Timothy Anderson (Clubb lab), Soohong Kim (Weiss lab) 2010-11 – Zeynep Durer (Reiser lab), Cecilia Zurita-Lopez (S. Clarke lab) 2009-10 – Luki Goldschmidt (Eisenberg lab), Kristofer Webb (S. Clarke lab), Sheng Yin (Loo lab) 2008-09 – Nathan Joh (Bowie lab), Neil King (Yeates lab) Photos courtesy of Helen Houldsworth, the Molecular Biology Institute.
University of Michigan Health cardiologist named to U.S. Preventive Services Task Force
University of Michigan Health cardiologist Venkatesh Murthy, M.D., Ph.D., has been appointed to the U.S. Preventive Services Task Force.
Popular olive oil shot trend has Americans chasing health benefits as doctor questions the hype
Should you take olive oil shots to boost health? Harvard-trained doctor Nick Norwitz, M.D., Ph.D., shares what you need to know about the trending wellness habit.
Sanofi suspends chronic lung disease phase 2 study, tied to ‘strategic business reasons’
Sanofi halted a phase 2 trial testing a monoclonal antibody, SAR445399, in non-cystic fibrosis bronchiectasis, Fierce Biotech has learned. The trial, which began only back in April, was a randomized, double-blind, placebo-controlled study to measure the reduction in mucus plug score following treatment with SAR445399 compared with placebo in adults aged 18 to 80 years with NCFB, a chronic lung disease. The trial was officially reported as halted on July 29, the day before Sanofi’s second-quarter earnings call. The decision to pause the trial was made “as part of a company-wide portfolio review for strategic business reasons,” and not due to safety concerns, a Sanofi spokesperson told Fierce. The move to pause the NCFB trial comes during a trying time for Sanofi following a year filled with a series of trial fails. In February, the French pharma ousted CEO Paul Hudson and appointed Merck KGaA leader Belén Garijo, M.D., Ph.D., to steer the ship. Since then, Garijo has been doing a deep dive on correcting the company’s strewn R&D and clinical strategies. On July 24, Sanofi scrapped amlitelimab for atopic dermatitis, despite its lore as being a potential $5 billion blockbuster. During its second-quarter report, the company abandoned two more assets, balinatunfib and itepekimab, following failed trial results in psoriasis and chronic obstructive pulmonary disease, respectively. SAR445399, only first revealed by Sanofi in 2023, is an anti-interleukin-1 receptor 3 monoclonal antibody developed to block the interleukin 1, 33, and 36 cytokine pathways. These pathways can be important in chronic immune-related dermatologic diseases, such as atopic dermatitis and hidradenitis suppurativa, as well as respiratory conditions, such as NCFB. Related Sanofi’s new CEO ‘looking deeply’ at late-stage pipeline as clinical clearout continues NCFB affects roughly half a million people in the U.S., with a global incidence of greater than one million cases. In August 2025, Insmed received FDA approval for Brinsupri, a DPP1 inhibitor targeting neutrophil activation, for treatment of NCFB in adults and kids ages 12 and older. The British biotech Infex Therapeutics showed promising NCFB phase 2a data using their monoclonal antibody, INFEX702, which acts by disabling Pseudomonas aeruginosa, a bacteria known to be a major pathogen of NCFB. Sanofi is currently running a separate phase 2 study testing SAR445399 as a potential treatment for the inflammatory skin condition hidradenitis suppurativa.
Ph.D. Recipient Dr. Sun Young Park Publishes on Gut Health Advertisement on TikTok
While earning her Ph.D. in Communication Theory and Research from Florida State University’s (FSU) School of Communication, Dr. Sun Young Park collaborated with Drs. Jaejin Lee and Braidyn Lazenby in her publication, “Gut health goes viral: analyzing influencer advertising for dietary supplements on TikTok”. This research examined how TikTok creators discuss gut health and promote…
UAMS Names Wendy N. Nembhard, Ph.D., MPH, as Dean of the Fay W. Boozman College of Public Health
LITTLE ROCK — The University of Arkansas for Medical Sciences (UAMS) named Wendy N. Nembhard, Ph.D., MPH, as the next dean of the Fay W. Boozman College of Public Health, effective Sept. 1.
AbCellera women’s health data top ‘most aggressive upside scenario,’ putting Astellas and Bayer on notice
AbCellera has reported phase 2 results “beyond even the most aggressive upside scenario” that its CEO dared to consider, boosting the biotech’s chances of challenging Astellas and Bayer for a women’s health market. The phase 2 clinical trial compared ABCL635, an antibody targeting NK3R, to placebo in patients with hot flashes caused by menopause. Investigators enrolled 92 postmenopausal women experiencing a mean of about 10 moderate or severe hot flashes per day. By Week 4, the number of moderate or severe hot flashes had fallen by a mean of 8.8 on ABCL635 and by 3.5 on placebo. That statistically significant, placebo-adjusted reduction of 5.3 hit the trial’s primary endpoint. The level of efficacy also cleared the bar set by existing drugs. While cross-trial comparisons can be misleading, AbCellera CEO Carl Hansen, Ph.D., had seen enough to start hyping the program. “We now view ABCL635 as a potential best-in-class non-hormonal therapy with strong differentiation against approved NK3R competitors across all important dimensions, including efficacy, safety, dosing and convenience,” Hansen said on a Monday morning conference call with investors to discuss the data. “We believe ABCL635 is now a highly de-risked program.” Last week, Hansen used AbCellera’s earnings call to set expectations for readout, with the CEO defining success as a clean safety profile and efficacy comparable to the two approved small molecules. The data vaulted over that bar. Astellas linked (PDF) one of the small molecules, Veozah, to placebo-adjusted reductions in hot flash frequency of 2.1 and 2.6 at Week 4 of its two phase 3 trials. Bayer reported (PDF) placebo-adjusted reductions of 3.04 and 3.29 at Week 4 of pivotal studies for its small molecule, Lynkuet. At 5.3, the placebo-adjusted reduction in AbCellera’s trial comfortably cleared the standard set by the incumbents. Veozah and Lynkuet came to market based on evidence of their ability to reduce the frequency and severity of hot flashes. AbCellera’s phase 2 study covered both endpoints, with the Canadian biotech reporting a mean reduction in severity of 1.4 points at Week 4 on ABCL635, compared to 0.3 points for placebo. Again, the placebo-adjusted result compares favorably to data on Veozah and Lynkuet. Analysts shared Hansen’s enthusiasm for the data. The phase 2 results “firmly validate ABCL635 as a potentially best-in-class treatment,” BMO Capital Markets analysts said in a note to investors Monday. ABCL635’s apparent efficacy edge “is likely attributable to the higher dosing/target engagement the asset is able to reach vs. the oral agents due to its wider therapeutic index,” the analysts added. The analysts, who model $2.3 billion in unadjusted peak sales for ABCL635, flagged the safety profile as another positive of the phase 2 readout. While Veozah carries a boxed warning for liver damage, nobody on ABCL635 in the phase 2 trial had elevated liver enzymes or bilirubin values. If replicated in phase 3, the lack of a liver signal could allow approval without the monitoring requirements imposed on Veozah. Investors appeared equally enthused, sending AbCellera's stock up 32% to $9.21 in premarket trading Monday from a Friday closing price of $6.93. Next, AbCellera will collect the Week 12 data and talk to its advisors about further development. The results open up “a wide variety of possibilities of how we might take this forward into phase 3 studies to truly maximize the value of the asset and make sure that ABCL635 is able to demonstrate its differentiation potential,” Sarah Noonberg, M.D., Ph.D., AbCellera’s chief medical officer, told investors.
Booming Business: Atlanta Firm Creates Cleaner Way to Sop Up Oil Spills
After the Deepwater Horizon spill, o-founder and CEO Sudhir Sharma, a Georgia Tech Ph.D. and chemical engineer, started wrestling with how to actually clean up spilled oil instead of just moving the problem from the ocean to the landfill.
Research Universities Are Admitting Fewer Ph.D.s, a Bad Sign for Science
Some of the nation’s top research universities are shrinking doctoral programs because of uncertain federal funding.
Moving science out of silos: A conversation with biochemist and philanthropist Mick Hitchcock, Ph.D.
Biochemist Mick Hitchcock reflects on his career in pharmaceutical innovation and his commitment to advancing science and communication at the University of Nevada.
Huntsville business owner Natalia Infante brings human intuition to national brands through Hola Insights
Huntsville may be known for rockets, defense, and technology, but Natalia Infante, Ph.D., owner and founder of Hola Insights, a market research and insights agency, is proving the Rocket City is also a place where nationally recognized research firms can thrive. Infante recently sat down with the Huntsville Business Journal to share how her multicultural […]
Texas Tech University Health Sciences Center Awarded Grant to Improve Diabetes Testing Access in Rural West Texas
The American Medical Association (AMA) awarded $50,000 to Adrian Billings, M.D., Ph.D., as part of a new grant to improve access to A1C testing in West Texas.
Yale doctor on caring for mental health in cancer patients
NEW HAVEN, Conn. (WTNH) — The mental state of cancer patients is a part of care that many people may not think about. Gabe Cartagena, Ph.D., the clinical director of the Yale Psycho-Oncology Progra…
A concussion expert and football father discusses why he values teamwork over zero-risk
U-M Health’s Jonathan Lifshitz, Ph.D., discusses why his work with concussions hasn’t changed his stance on his sons playing contact sports
3 Steps to Support Mental Health for Rural Youth
(Feature Impact) Young people face a growing number of pressures, including academic expectations, social responsibilities, complex family situations and uncertainty about their own futures. Mental health support is important for all – but in many rural areas, those pressures are even greater.According to the Centers for Disease Control and Prevention, the suicide rate for rural youth ages 15-19 is 74% higher than their urban counterparts. Barriers like limited insurance coverage, unreliable internet for telehealth, scarce providers, long drive times and lack of public transportation make it harder to get mental healthcare when it’s needed. Plus, asking for help can feel like opening oneself up to judgment and stigmatization.That’s why Rural Minds, the only nonprofit focused on mental health for rural communities, created the Rural Youth Mental Wellness pilot program supported by Boehringer Ingelheim. It was developed by an advisory committee made up of rural youth to provide their peers with practical, free, accessible mental health resources. Incorporating feedback on the pilot, the updated program sponsored by the Sompo Foundation is now launching its national rollout.“A young person’s ZIP code should never determine whether they can access meaningful mental health support where and when they need it,” said Jessica L. Schleider, Ph.D., director, Lab for Scalable Mental Health, Northwestern University. “Our lab is thrilled to partner with Rural Minds as they champion evidence-based, anonymous, freely available support tools designed to overcome barriers to help-seeking faced by rural youth across the country.”If the rural mental health crisis affects you or a loved one, consider these ways to help.Break the Stigma Surrounding Mental HealthIn communities where self-reliance is valued, asking for help can sometimes be viewed as a sign of weakness. Young people who feel unheard and unsupported often struggle with being vulnerable, so they continue carrying their increasingly heavy burdens alone.Parents, educators, healthcare providers, community leaders and peers can work to change that culture by normalizing mental health conversations. This includes helping teenagers feel seen and accepted by educating them on mental health issues and coping strategies, listening to their experiences without judgment, sharing your own stories and reminding them it’s courageous to seek support.Consider Single-Session InterventionsThe first step is always the hardest when it comes to seeking mental health support, and not every struggling young person is ready or able to see a therapist. With access to free, confidential, self-guided materials to begin building mental wellness skills, the first step may be less scary.Single-Session Interventions (SSIs) are brief, structured online courses designed to teach youth practical skills for handling stress, low mood, self-image and more. The Rural Youth Mental Wellness Program offers SSIs in partnership with Project YES (Youth Empowerment and Support), a free digital resource developed with Northwestern University’s Lab for Scalable Mental Health at the Feinberg School of Medicine.Anonymous access to SSIs through the partnership provides strategies for:Improving moodRethinking body imageReframing negative thoughtsKnowing your power to changeTaking steps toward goalsProtecting LGBTQ+ prideHandling self-harm urgesStaying safe amid dark thoughtsEach SSI typically takes 5-10 minutes. Although SSIs are not a replacement for therapy, they provide a research-backed source of support for young people experiencing bouts of stress or low-to-moderate distress.Know When to Seek Professional HelpSelf-guided resources and supportive conversations are a valuable starting point, but sometimes young people need qualified professional help. Look for symptoms like worsening mood or behavior, substance use, self-harm or difficulty managing everyday tasks, and take teens seriously when they express dark feelings.Doctors and counselors can provide personalized support for youth in crisis, and the 988 Suicide and Crisis Lifeline offers free, confidential 24/7 support for mental health by dialing 9-8-8.“I grew up in a small town where mental health was almost taboo,” said committee member Asheton Medlin. “Being part of the committee that built this program let me help make sure rural youth today have the support I didn’t. I’m excited to help bring these resources to them because this generation deserves the chance to grow up and change the world.”Find more information at RuralMinds.org.Photos courtesy of Shutterstock
5 Questions with Archer Graduate Fellow Christina Lildharrie
A Ph.D. student in neuroscience, she is exploring science, service and public policy in the nation’s capital.
Assistant Professor of Climate Data Science | The Journal of Blacks in Higher Education
Boston University invites applications for a faculty position at the rank of Assistant Professor in the Department of Earth Environment. This tenure-track position in Climate Data Science , beginning on July 1, 2027, is part of the ongoing cluster hire in Environmental Data Science and complements faculty searches within the Faculty of Computing and Data Science.rnrnWe particularly welcome candidates whose research focuses on the physical basis of climate, climate variability, and climate change, and who employ data science methodologies to deepen our understanding of how the climate system is changing and how these changes affect the global environment. Areas of interest include—but are not limited to—the changing frequency and intensity of extreme weather events; interactions between the atmosphere and terrestrial, oceanic, biospheric, and cryospheric systems; and improved understanding of Earth system predictability at seasonal, decadal, and longer time scales. We envision this position playing a central role in connecting and enhancing existing departmental strengths in climate-related research and teaching, including terrestrial and marine biogeosciences, land surface and coastal processes, paleoclimatology, energy and economic policy, and environmental sustainability. This faculty member will also contribute to university-wide interdisciplinary initiatives — including the Urban Biogeoscience and Environmental Health (URBAN) program, the Institute for Global Sustainability, and the Center for Climate and Health at the School of Public Health — and is expected to develop collaborative ties with the Faculty of Computing and Data Sciences, where shared interests in machine learning, large-scale data analytics, and Earth system modeling provide natural ground for joint advising, co-teaching, and grant development. This hire reflects our commitment to advancing interdisciplinary scholarship at the intersection of climate and data science. This position contributes to the University convergence themes of Global Sustainability as well as Artificial Intelligence, Data Science, Computing that are core pillars of BU's cross-disciplinary research priorities.rnrn Position Qualifications:rn Candidates should have a PhD or equivalent degree, demonstrated ability to obtain external funding to support their program of research and scholarship, and a commitment to excellence and innovation in teaching, education, and mentorship of students. The successful applicant will be expected to supervise graduate research in Ph.D. programs, teach at all levels in the Earth Environment curriculum, and maintain an externally funded research program. We seek applicants whose research complement strengths in the Department and around the University. For more information about the Department, see
Reimagining the treatment of mental health: Maria Carolina Bittencourt Gonçalves
By Jessica Leff Listen to Maria tell her story | Wyss Institute · Maria C. B. Gonçalves – Reimagine the WorldMaria Carolina Bittencourt Gonçalves, Ph.D., grew up in São Paulo, Brazil, the largest city by population in South America. It’s comparable to New York, but with a tropical climate. “I knew I wanted to be...
UF Diabetes Institute expands care across Florida with support from Google
UF Diabetes Institute Director Todd Brusko, Ph.D., speaks at Thursday's event announcing funding from Google.org to boost diabetes care in Florida. (University…
St. Mary’s Environmental Science Professor discusses Mars garnet
Professor of Environmental Science (and rock star) David Turner, Ph.D., talks about why finding possible Mars garnets is significant.
NMSU computer science undergraduate research experience leads students toward Ph.D.
New Mexico State University computer science students were among 120 attending the inaugural in-person workshop and research showcase for the Computing Research Association (CRA) Undergraduate...
NIH Renews Prestigious Training Grant for NC State Ph.D. Students Preparing to Lead Complex Research Teams
The National Institutes of Health has approved a $2.5 million grant for the NC State College of Veterinary Medicine to continue the work of its Comparative Molecular Medicine Training Program, which awards fellowships to Ph.D. students in NC State University’s Comparative Medicine Institute. Since NIH first funded the program in 2021, more than 20 students…
The Harvard Crimson (@theharvardcrimson)
83 likes, 0 comments - theharvardcrimson on October 6, 2026: "Harvard’s Faculty of Arts and Sciences is launching 25 tenure-track faculty searches, FAS Dean Hopi E. Hoekstra announced in a Monday email to faculty, further loosening a University-wide hiring freeze instituted last spring as the school draws an influx of philanthropic support. The searches, which include positions across the FAS’ three divisions and the School of Engineering and Applied Sciences, come less than a week after Hoekstra announced the school would also be upping Ph.D. admissions for the upcoming admissions cycle — and as the University continues soliciting support from donors for its academic programming. Full story linked in bio. 🖋: Abigail S. Gerstein and Amann S. Mahajan 📷: Mae T. Weir".
The fun and flexibility of data science
Taylor Bolt spent his Ph.D. and postdoc digging through brain imaging data for clues to cognition. In industry, the datasets are different but the joy of answering questions with data remains.
This grad’s company helps drugs get developed faster and cheaper
Flow cytometry services help biotech startups test new drugs. A Northeastern Ph.D. grad built SauveBio to make them cheaper.
Thomas Best, M.D., Ph.D., Earns ACSM Honor Award for Transforming Sports Injury Recovery
Dr. Thomas Best receives ACSM’s highest honor for pioneering sports injury recovery research and mentoring the next generation of clinicians.
Richard E. Carson, Ph.D., receives SNMMI 2026 Paul C. Aebersold Award for Outstanding Achievement in Basic Nuclear Medicine Science
Richard E. Carson, PhD, has been named the 2026 recipient of the prestigious Paul C. Aebersold Award. Carson is professor of Biomedical Engineering and of Radiology and Biomedical Imaging at Yale University in New Haven, Connecticut, as well as emeritus director of the Yale PET Center. The award was announced by the Society of Nuclear Medicine and Molecular Imaging (SNMMI) during its 2026 Annual Meeting.
Mercer political science professor brings fun, games to classroom
Games and simulations are a tradition in the courses taught by Phoebe Moon, Ph.D.
Beacon of discovery
Biomedical science Ph.D. student Lucy Williamson conducts cancer cell research in a Whitley H35 Hypoxystation, which creates hypoxic conditions within a controlled and sustained workstation environment in the Mugar Life Sciences building.
Mercer political science professor brings fun, games to classroom
Games and simulations are a tradition in the courses taught by Phoebe Moon, Ph.D.
Retired Rear Admiral Tim Gallaudet Talks Marine Science, Leadership At St. Mary’s College
LEXINGTON PARK, Md. — The Patuxent Partnership and the Steny H. Hoyer Center for the Study of Democracy at St. Mary’s College of Maryland hosted an evening with Rear Admiral Tim Gallaudet, Ph.D., USN (Ret.), on Sept. 30, at the College’s Dodge Performing Arts Center. The recital hall was full, with SMCM college students, alums, […]
KSU master’s graduates benefit from NIH-funded bridge program
Recent Kennesaw State University graduate April Ford engaged in a program designed to help master’s students in the College of Science and Mathematics gain the experience they needed to pursue doctoral degrees elsewhere. She’ll stand as an example of the Peach State Bridges to the Doctorate program’s effectiveness, having earned her Master of Science in Integrative Biology (MSIB) and acceptance into a Ph.D. program. Ford, Jojo Croffie, and Lindsey Knight all earned their MSIB degrees, and thanks to enrichment through the Peach State Bridges to the Doctorate program, each will start a Ph.D. in the fall.
Get free personal training while helping Exercise Science students build skills
Key takeaways: For Exercise and Sport Sciences students, working with someone they don’t already know provides an important opportunity to translate classroom learning into practical experience. All Exercise Science students have the opportunity to serve as student trainers during their senior year, said Jason Casey, Ph.D., associate professor of Exercise Science. “We greatly value these […]
Rebuilding the Innovation Engine: How We Got Here And What Comes Next
Federal investment in basic science built America’s innovation engine, but declining support is threatening U.S. leadership, writes Dietrich Stephan, Ph.D.
Science, Public Health, and the Politics of Truth
Presented as part of the McCloskey Speaker Series.Peter Hotez, M.D., Ph.D., professor and dean of the National School of Tropical Medicine at Baylor College of Medicine, joins the Aspen Institute for a keynote lecture on the intersection of science, medicine, and public trust. A leading authority on vaccines and neglected tropical diseases, Hotez reflects on the challenges facing public health today, the growing politicization of science, and what it will take to rebuild trust in scientific institutions in the years ahead.Paepcke Auditorium, doors at 5:00 pmRegistrationThis event is free and open to the public, but registration is required, and capacity is established on a first-come, first-served basis. Once an event is at capacity, we will have an in-person waitlist at the door.Public registration is now open for summer 2026. Please click here to register.ParkingParking is very limited. Please carpool, walk, bike, or ride RFTA.Book signing will immediately follow the event. To learn more about his book or to order a copy, please click here.
NMSU research program helps computer science students picture a Ph.D. path
NMSU computer science students joined a national undergraduate research program that helps students explore research careers and prepare for graduate school.
Survey of Young Researchers Raises Concerns Over Future of Science in U.S.
Fewer planning careers in academy, nation, and more doubt value of Ph.D. amid policy shifts in funding, international students.
Upcoming Science Cafe
BAR HARBOR—Join us for a fascinating Science Cafe with environmental toxicologist Nishad Jayasundara, Ph.D., as he explores how everyday contaminants and other stressors such as heat exposure may be quietly influencing kidney health. Chronic kidney disease (CKD) affects nearly 1 in 7 adults in the United States—and more than 840 million people worldwide. While factors like diet and genetics are well known, scientists are increasingly uncovering another important piece of the puzzle: environmental exposure. Drawing on his team’s research, Dr. Jayasundara, Maine INBRE alum as a College of the Atlantic undergraduate student and past MDI Bio Lab Visiting Scientist, will share how early-life exposure to environmental toxins can disrupt kidney development, and may affect kidney structure and function in adults. Blending cutting-edge research with real-world relevance, this Science Cafe will shed light on an important and often overlooked contributor to human health—and what it could mean for communities around the world. Monday, August 17, 2026 at 5 p.m.Hybrid event at Maren Auditorium and via Zoom Register Now What Are Science Cafes? MDI Bio Lab’s Science Cafes provide an informal introduction to ground-breaking biomedical research by its scientists, scholars from near and far and from local experts in other fields as well. Each Cafe lasts about one hour; the floor is open for questions and discussion. It can get lively and it’s always engaging. MDI Science Cafes are open to the public and free of charge. For more information, or to watch past events, visit our website. The MDI Science Cafe Series is brought to you by Cross Insurance. Subscribe Share Leave a comment
NYC Health + Hospitals Appoints Hillary Jalon and Manny Saez, Ph.D., to Senior Vice Presidents - NYC Health + Hospitals
NYC Health + Hospitals today announced the appointments of Hillary Jalon as Senior Vice President and Chief Quality Officer and Manny Saez, Ph.D., as
When computer science meets the alpaca immune system
After earning bachelor's and Ph.D. degrees in bioengineering with a focus on molecular biology, Will White, a postdoctoral scholar in the Department of Computer Science at Tufts, was pretty certain his ...
Survey of young researchers raises concerns over future of science in U.S.
Fewer planning careers in academy, nation, and more doubt value of Ph.D. amid policy shifts in funding, international students
Prominent Team Owner Shares Leadership Lessons on the Future of Profes
Carolyn Tisch Blodgett, co-owner of the New York Giants and Gotham FC, joined President Jens Frederiksen, Ph.D., for the latest Sports Leadership Exchange Speaker Series, as part of the Frederiksen Fo
Reimagining how scientists study the chemistry of the air
Professor Victoria Barber and doctoral student Cooper Crabtree are spearheading Keck Foundation-funded project charting a path toward better understanding atmospheric oxidation. by Álvaro Castillo, UCLA College of Letters and Science From the vantage point of Victoria Barber, a UCLA assistant professor of chemistry and biochemistry, understanding the chemical reactions that shape air quality and climate are among the most pressing scientific challenges of our time. And thanks to a recent grant from the W.M. Keck Foundation, she and doctoral student Cooper Crabtree will spearhead a new research project exploring exactly how pollutants form in the atmosphere. Specifically, the project will examine how volatile organic compounds transform through atmospheric oxidation and explore how pollutants, like smog, form in the atmosphere. VOCs are released by sources ranging from trees and wildfires to vehicle exhaust pipes and consumer products such as cologne and perfume. As they undergo atmospheric oxidation, they can transform into a wide range of other compounds. Anyone in Southern California can attest to the urgency of this area of research — for example, in late July of this year, Los Angeles County was under an active ozone pollution advisory for almost a full week. While many people associate ozone with the protective ozone layer high in the stratosphere, ground-level or tropospheric ozone is a harmful secondary pollutant formed through atmospheric oxidation. Understanding how VOCs transform into pollutants like ozone is therefore critical to improving air-quality forecasts and informing strategies to reduce exposure. “My group is focused on trying accelerate our understanding of these networks of reactions so that we can do a better job of predicting how those pollutants form,” Barber said. “When we make decisions about how we might alter emissions, we can understand how that’s going to influence the production of these downstream pollutants.” With support from the W. M. Keck Foundation, Barber and Crabtree are developing new experimental approaches that will combine — and improve — techniques to study hundreds of chemical systems more efficiently than traditional methods allow. Instead of spending years decoding a single VOC, the project seeks to dramatically expand the pace and scale of discovery. The grant comes at a particularly important moment for environmental research. Barber, who joined UCLA in 2023, says funding for climate and air-quality research, especially for early career scientists, has become increasingly difficult to secure, a challenge compounded for ambitious projects that require building entirely new research infrastructure. The Keck Foundation’s support, Barber said, provides the flexibility to pursue bold early-stage, high-risk ideas that may be more difficult to fund using conventional federal funding sources. “It’s really, really hard to do environmental research under the current federal paradigm,” Barber said. “By stepping in and providing stable and flexible funding to explore this new idea, the Keck Foundation is making a huge difference to my research program.” In addition to funding early-career faculty, the Keck Foundation’s support is also focused on empowering graduate students like Crabtree in their scientific growth. The project gives Crabtree the opportunity to help develop an entirely new experimental approach to studying atmospheric chemistry — an experience that will provide him with valuable technical skills, scientific training and preparation for the next stage of his career. Stable funding also allows doctoral students like Crabtree to devote themselves more fully to research rather than balancing their scientific work with additional teaching responsibilities needed to cover funding gaps. “Getting to devote more of my time to research this past school year has greatly improved the pace and quality of our experiments, data analysis and planning for our future work,” said Crabtree, who is pursuing a Ph.D. in chemistry. “I feel very lucky — especially amid the current uncertainty surrounding scientific funding — to be able to continue exploring exciting knowledge gaps in our field and growing as a scientific researcher.” For Barber, mentorship is among the most rewarding and important aspects of her role as a faculty member. “Our jobs as faculty are to do good science and make good scientists,” she said. “I believe the Keck Foundation shares this belief and sees the potential positive impact this project can have.”
Science is under pressure again. Here’s what that means for young researchers
When Emma Scales decided she wanted to be a scientist, it seemed logical—simple, even. Now a Ph.D. candidate at Cornell University, Scales is studying symbiosis, specifically the way bacteria can gro...
Lucia S. Tsaoussi, Ph.D.
Dr. Tsaoussi serves as the Program Manager for NASA’s Space Geodesy program
UAMS names Nembhard as dean of the Fay W. Boozman College of Public Health
The University of Arkansas for Medical Sciences named Wendy N. Nembhard, Ph.D., MPH, as the next dean of the Fay W. Boozman College of Public Health, effective Sept. 1. Nembhard succeeds...
South Florida Business Journal Features NSU Research Leader in Discussion on Broward County’s Economy
NSU’s Robert Smith, Ph.D., interim assistant vice president of research, joined business, government, healthcare, and transportation leaders at the South Florida Business Journal’s Broward Forward Roundtable to discuss what will drive the county’s next phase of economic growth. Smith shared… Continue Reading →
Ph.D. admissions have dropped 15% for the new school year
That could weaken the doctoral pipeline — and spell trouble for the future of science and innovation in the U.S.
Rear Admiral Tim Gallaudet To Discuss “Marine Science & Technology Leadership In Turbulent Times” At St. Mary’s College
LEXINGTON PARK, Md. – The Patuxent Partnership and the Steny H. Hoyer Center for the Study of Democracy at St. Mary’s College of Maryland will present an evening with Rear Admiral Tim Gallaudet, Ph.D., USN (Ret.), on Wednesday, September 30, from 5:00-7:00 p.m. at the College’s Dodge Performing Arts Center. Gallaudet, former acting administrator of […]
The NSF’s Ph.D.-to-Industry Pipeline Push
The majority of STEM Ph.D.s take jobs outside academia. While some universities help them prepare, the National Science Foundation is now investing millions to boost those efforts.
Mark Nelson, Ph.D., Elected to the UK’s Academy of Medical Sciences
Mark Nelson, Ph.D., University Distinguished Professor and chair of pharmacology at the Robert Larner, M.D. College of Medicine at the University of Vermont, has been named a 2026 Fellow of the Academy of Medical Sciences.
AZ's R&D chief Barr touts internal 'science success story' after IL-33 antibody's stellar showing in COPD
With a detailed data drop that AstraZeneca’s R&D chief described as an internal “science success story,” the British Big Pharma has secured an FDA priority review for what it believes could become a flagship biologic in chronic obstructive pulmonary disease (COPD). In detailed results from the late-stage Oberon and Titania trials—first teased in March and detailed in full at the European Respiratory Society Congress in Barcelona this week—the drugmaker laid out the extent of its IL-33 inhibitor’s potential to reduce moderate and severe exacerbations in a wide range of COPD patients still struggling with those “lung attacks,” as AstraZeneca’s Sharon Barr, Ph.D., called them, despite using standard-care inhaled therapy. In the headline results, a 300 mg dose of tozorakimab given once every four weeks curbed those moderate and severe exacerbations in the studies’ primary population of former smokers by 29% in the Oberon study and 34% in Titania. In the overall population of both current and former smokers, these reductions were 30% and 29%, respectively, versus placebo and inhaled standard of care. The benefits also extended to clinically meaningful exacerbation reductions in all prespecified patient subgroups and specifically turned up promising signals in patients across a range of blood eosinophil counts, with Barr telling Fierce that “it’s the details that make this even more exciting than the high-level results that we’ve already shared.” In fact, during AZ’s tozorakimab poster presentation at the ERS 2026 Congress this past weekend, attendees were so enamored by the data that event organizers had to encourage people to clear the room and look at the other presentations on offer, Barr said in an interview. “I think it really speaks to the fact that there is a lot of buzz around these data because the entire respiratory community has been so desperate for new therapies for these patients,” she explained. The respiratory disease continues to represent a “staggering unmet medical need,” Barr said, highlighting the COPD exacerbations that the Oberon and Titania studies homed in on, which she added carry a greater mortality risk than a heart attack. “When a patient has a severe exacerbation, only about half of them are still alive within three and a half years,” she pointed out. As for tozorakimab specifically, Barr christened the molecule “an AstraZeneca science success story,” harkening several years back to the point at which researchers began to explore IL-33 as a driver of respiratory disease, and COPD in particular. At the same time, “there was still so much that wasn’t understood,” she admitted, highlighting the insight that IL-33 signals through both ST2 and EGFR through the RAGE pathway, a discovery Barr attributed to AstraZeneca's own scientists. Understanding the need to tackle both pathways in COPD—and aware of competitor candidates in the hopper, including one that bound ST2—the company ultimately had to make some “courageous decisions,” Barr said. These included taking a prior COPD molecule offline and going back to the drawing board to reinvent its potential IL-33 label “to make sure that we had a molecule that could block signaling through both arms of the pathway, through both the reduced form and the oxidized form, knowing that we wouldn’t be first, but striving to be best.” “When we put [tozorakimab] into the clinic, we firmly believed that we had a differentiated molecule, and we saw the other molecules blocking just ST2 or partially blocking IL-33, unable to deliver two positive pivotal studies in COPD,” Barr explained. “We kept marching forward because we believed our molecule was differentiated, and now I think we have the clinical validation that supports that.” Ultimately, AstraZeneca finds itself on much better footing these days when it comes to potential biologic rivals to tozorakimab in COPD. Sanofi and Regeneron’s Dupixent, for instance, is approved to treat COPD exacerbations in patients with high eosinophil counts, but not low ones. Meanwhile, the future has become cloudier for other next-gen IL-33 candidates from Sanofi and Regeneron, as well as Roche, which have suffered trial flops in recent years. One other potential ingredient for AstraZeneca’s success in its duo of studies was that the company was “ambitious in the trial design, willing to look at an all-comers population,” Barr said, “and willing to enroll the most severe patients.” Prior studies for would-be biologics rivals in COPD “avoided enrolling” those patients, she pointed out. She also highlighted the Big Pharma’s painstaking design of exacerbations in its trial, which “gave us a very rigorous readout,” and pointed to “the extra effort and investment” the company put in to understand the effect of mucus plugs in patients. Barr described mucus production as a “key feature in disease diversity,” noting that mucus plugs—obstructing clumps of mucus that block patients’ airways—are associated with worse outcomes in COPD. In its data announcement, AstraZeneca noted that an integrated analysis of Oberon and Titania found tozorakimab “demonstrated a reduction in patients’ mucus plug score,” with the pharma claiming its biologic is the first to deliver such results in a broad COPD population. “So being able to reduce those mucus plugs, we expect, is an important part of driving benefit for patients who are living with COPD,” Barr said. Again touching on the breadth of the study populations, Barr added that tozorakimab “worked across all eosinophil levels in both current and former smokers across all levels of lung function,” which she suggested “really simplifies decision-making for clinicians, and it allows them to offer therapy to the broadest possible patient population.” In the highest patient eosinophil count group, tozorakimab helped chart a 43% reduction in exacerbation risk, which Barr stressed were “unprecedented data.” In the mid-level group, AZ’s drug delivered a 23% reduction and, in the lowest group, a 34% reduction in eosinophils, which Barr said suggests efficacy “in all patient subgroups.” As for AZ’s recent guidance upgrade on the medicine’s sales opportunity, the lift from a $3 billion to $5 billion range to $5 billion plus was informed by multiple factors, Barr said, including the fact that “in 2024, there were multiple competitors, and there aren’t anymore.” Additionally, “we know that this is a massive unmet medical need, and this is a really incredible set of data that we think will be very convincing to the clinical community,” Barr said. Looking ahead to a potential evolution of the COPD treatment landscape, Barr noted that most patients start treatment in the community with an option like a triple therapy, and for them, having an option like AstraZeneca’s inhaler Breztri will remain a “really important part” of that journey. But of the patients uncontrolled on triple therapy, which Barr described as “about half of them today,” just a “small fraction” are currently eligible for biologic therapy, which she emphasized AstraZeneca is working to change. Understanding that COPD is not a “one-size-fits-all” disease, AstraZeneca is also looking at its antibody drug Tezspire for patients with T2-driven disease, and the company continues to think about new mechanisms for tackling COPD through both systemic and inhaled drugs, Barr said.
Texas Tech University Health Sciences Center Appoints New Graduate School of Biomedical Sciences Dean and Vice Dean
TTUHSC has named Lance R. McMahon, Ph.D., as the new Graduate School of Biomedical Sciences dean and Kendra P. Rumbaugh, Ph.D., as vice dean.
World leader in livestock fertility research closes out 58-year career
After 58 years, Fuller Bazer, Ph.D., University Distinguished Professor, Department of Animal Science, will close out his scientific career