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Australia's huntsman fastest spider on record, new study suggests
A species of huntsman spider found in Queensland is the fastest mover out of more than 250 spider species analysed in a new study.
J.K. Simmons says he’s never met Tom Holland despite being in 2 of his “Spider-Man” movies
The Oscar winner has played J. Jonah Jameson to Holland’s Peter Parker.
Galaxy Z Fold 8: Here's an Official Look at the New Foldable
There isn't much we don't know about the upcoming Galaxy Z Fold 8 and Galaxy Z Fold 8 Ultra from Samsung. Thanks to countless renders leaking and the official reveal date set at July 22, we're...
Samsung shares first official glimpse at wide Galaxy Z Fold 8, with Spider-Man’s help
Samsung has dropped a new Galaxy Z Fold 8 teaser, offering a quick glimpse of the wider new form factor...
China bets on AI to speed up science despite chip limits
Driven by aggressive state policies and a national supercomputing network, Chinese labs are rapidly embedding AI into daily research
NAVER D2SF Invests in 23i, a Virtual Entertainment Startup
NAVER D2SF, the corporate venture capital arm of NAVER, has made a new investment in 23i (CEO, Hyungmin Kim), a virtual entertainment startup. As the global virtual entertainment market continues to grow rapidly, particularly in Korea and Japan, NAVER D2SF decided to invest in the team based on its ability to create expanded entertainment IP through strong content production capabilities and an in-house technology pipeline designed to maximize the strengths of virtual artists.
Students Connect NASA Science With Indigenous Knowledge to Study Coastal Erosion
For the Pleasant Point Passamaquoddy Reservation, or Sipayik, the ocean has always been a teacher. Situated in what is known as Downeast Maine, along the shores of Passamaquoddy Bay, generations of Indigenous people have lived along the coast, learning from the tides, the land, and their elders. But today, the shoreline is changing more rapidly. Coastal erosion is slowly taking land away. Land that already holds a history of loss.
Holland packaging company buys former Howard Miller Clock facility for $15.9M
Coastal Container plans to use the facility to meet ongoing growth as it makes other investments.
Terri’s Treasures: Lapidary artist turns lifelong passion into business
Sarasota jeweler handles every step of the process, from raw stone to finished piece
Racing Spiders Reveal The Fastest On Record Tops 8 Miles Per Hour – That’s Faster Than Most Humans Jog
Gulp.
A Boeing 737 plane has disappeared off the coast of Pakistan
The K2 Airways cargo plane from Pakistan, carrying five crew members, was recorded rapidly descending before losing contact.
El-Sayed, Stevens trade pointed barbs in Democratic US Senate debate
With four weeks to go until the Aug. 4 primary, the two Democrats held a debate in Grand Rapids hosted by WOOD-TV8
INCUBASE Studio Accelerates Collectible Entertainment with GochaGocha's 23-Location Asia Debut of a New Photo Card Experience
INCUBASE Studio is expanding its IP entertainment ecosystem with the launch of GochaGocha, a new smart photo card machine platform developed by subsidiary INCUTix. Following a rapid rollout across 23 locations in Hong Kong, Taipei, Kuala Lumpur and Bangkok in early June, GochaGocha introduces a new channel connecting fans with officially licensed content through discovery, collectability and convenience.
DenOtter would change how politics is done
HOUGHTON — Republican Congressional candidate Matthew DenOtter is running for election to the U.S. House to represent Michigan’s 1st Congressional District. He is hoping to unseat incumbent Jack Bergman. The 1st Congressional District contains the 15 counties of the Upper Peninsula and 20 counties in the Lower Peninsula. “I grew up in Grand Rapids. I […]
Mitch McConnell, Joe Biden and the growing epidemic of politicians hiding health problems
Politicians are increasingly hiding their health problems, despite a national reckoning over the problem during the presidency of Joe Biden.
Spring Lake businesses district fire impacts two shops
Spring Lake Fire Department units arrived to find three floors of a building on Third Avenue on fire, and they saved two shops from total devastation.
Cyclosporiasis outbreak: Cases rise to over 700 in Michigan, 36 reported hospitalizations
A parasite outbreak continues to rapidly rise in Michigan, with state health officials reporting more than 700 cases.
WHO says progress stalling on air pollution, and other health stories
Top stories: Air pollution progress stagnates - WHO; Ebola epidemic impacting livelihoods - UN; World's largest database of human genomes released.
Intelligent Computing appoints Philip S. Yu and Osmar R. Zaïane as new editors-in-chief
Intelligent Computing, a Science Partner Journal co-founded by Zhejiang Lab and the American Association for the Advancement of Science(AAAS), has appointed Philip S. Yu and Osmar R. Zaïane as its new Editors-in-Chief. Philip S. Yu and Osmar R. Zaïane succeed the journal's founding Editors-in-Chief at a pivotal stage of development, as Intelligent Computing continues its rapid growth as an international open-access journal dedicated to advancing the convergence of intelligence and computing.
What If We Could Spread Compassion Like a Disease?
Researchers are exploring what epidemiology—the science of how disease spreads—might teach us about spreading compassion.
Cyclosporiasis outbreak: Michigan health officials provide more tips on prevention as cases rise
As cases of a parasite outbreak continue to rise rapidly in Southeast Michigan, state health officials have issued additional recommendations to prevent foodborne illnesses.
Church services dull pain, and a new diabetes drug: science stories of the week
From new types of spider hunting techniques to the earliest-known plague victims, here are the most interesting recent scientific developments
Next American Sports Pro and QuickBuzz Announce Strategic Partnership to Build a Global Sports & Entertainment Digital Ecosystem
Ten-Year Collaboration Aims to Drive Subscriber Growth, Fan Engagement, and Long-Term Digital InnovationLondon, UK, July 06, 2026 (GLOBE NEWSWIRE) -- Next American Sports Pro (NASP), a rapidly expanding sports media and athlete development organization, today announced the signing of a strategic Memorandum of Understanding (MOU) with QuickBuzz to collaborate on creating one of the world's largest integrated sports and entertainment digital ecosystems. The partnership combines NASP's growing spor
'I know Toure will be really successful'
Bazoumana Toure's positivity translates on to the field. The rapid winger certainly tried to make things happen at Hoffenheim, who narrowly missed out on qualifying for the Champions League last season. Of the forwards playing in the Bundesliga in 2025-26, Toure ranked first for successful crosses (39), joint-second for assists (nine), joint-third for dribbles completed (48) and fourth for chances created (45) and big chances created (11).
Sky owner strikes £1.6bn deal to buy ITV broadcasting in ‘rapidly changing’ media landscape
Rolling coverage of the latest economic and financial news
International Business Machines (IBM) Joins Hands With Deloitte and Red Hat Against Automated Cyberattacks
International Business Machines Corp. (NYSE:IBM) is one of BlackRock’s 30 most important AI stocks right now. On June 26, International Business Machines Corp. (NYSE:IBM), together with Deloitte and Red Hat, formed a partnership to help provide businesses with greater protection against rapidly evolving, automated cyberattacks targeting the software supply chain. To increase the security of […]
Political rivals, Lapid, Edelstein, surprisngly align on national priorities
Both men are defining Israeli politics not through the traditional categories of Left and Right, but through questions of national responsibility, military service, and national consensus.
Zendaya spins a web of archival fashion in Rome
While promoting "Spider-Man: Brand New Day" in Rome, Zendaya wore a vintage Giorgio Armani dress festooned with delicately beaded cobwebs.
FULL SHOW: Inside INdiana Business 7/5/26
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Gukesh, Praggnanandhaa at Super Rapid and Blitz Croatia; medal chances at Asian Youth Table Tennis Championships: Indian Sports LIVE, July 4
Here are all the updates from Indian sports on July 4, 2026.
Gukesh, Praggnanandhaa compete at Super Rapid & Blitz Croatia 2026: Indian Sports LIVE, July 3
Here are all the updates from Indian sports on July 3, 2026.
Gukesh, Praggnanandhaa compete at Super Rapid & Blitz Croatia 2026: Indian Sports LIVE, July 3
Here are all the updates from Indian sports on July 3, 2026.
James Carville breaks with famous ‘It’s the economy, stupid’ slogan because of Trump
James Carville says his famous 1992 catchphrase "It's the economy, stupid" now haunts him because of what he calls Trump's corruption today.
Amendment 61: A.4 Rapid Response and Novel Research in Earth Science Final Close Date Deferred
A.4 Rapid Response and Novel Research in Earth Science (RRNES) solicits proposals that advance the goals and objectives of NASA's Earth Science Division by
Trial for Bundibugyo Ebola treatment starts in DRC, WHO says
A treatment trial for the Bundibugyo Ebola outbreak in the Democratic Republic of Congo enrolled its first patient on Thursday, marking a milestone in efforts to combat the epidemic, WHO chief Dr. Tedros Adhanom Ghebreyesus told reporters.
Computer science society creates new research integrity role to address case backlog
AndreyPopov/iStock Over the last five years, the Association for Computing Machinery has been dealing with a rapid rise in allegations of research misconduct that have created a backlog of cases to…
WHO, Member States discuss expanding South-East Asia Emergency Health Fund SEARHEF
With climate-related disasters, disease outbreaks and other health emergencies becoming more frequent and complex across South-East Asia, WHO and Member States today discussed measures to strengthen and expand the South-East Asia Regional Health Emergency Fund (SEARHEF) to ensure countries have rapid access to life-saving support when crises strike. "Health emergencies are becoming more frequent, more complex and more costly. Countries need rapid, flexible financing that can be mobilized immediately when lives are at risk. SEARHEF represents regional solidarity in action, enabling Member States to support one another when emergencies strike," said Dr Catharina Boehme, Officer-in-Charge WHO South-East Asia Region. She was addressing the Fifteenth Meeting of the Working Group on the Governance of SEARHEF.
Trinity Health Grand Rapids works to offer more free medication
Trinity Health Grand Rapids is rolling out a new program that aims to get prescription medicine to some of the lowest-income patients in West Michigan.
World Of Warcraft Is Finally Fixing Its Stupidest Settings Problem
I do not have time to pick up all of these Rust-Covered Blunderbusses
Protecting Science. Advancing HIV Prevention. Preparing for What's Next
Global health is being reshaped by rapid geopolitical shifts, scientific breakthroughs and the growing role of artificial intelligence — creating both new opportunities and new challenges. Translating scientific breakthroughs into impact requires protecting research, advancing equitable access and ensuring communities are at the center. Explore AVAC’s latest resources to help navigate and shape what comes […]
Enter The Sadie-Verse
After ‘Stranger Things’ and ‘John Proctor Is the Villain,’ Sadie Sink is burning up stage and screen in equal measure. Next stop: ‘Spider-Man: Brand New Day.’
AI-Driven Restructuring Accelerates Layoffs Across U.S. Technology Sector
Artificial intelligence is rapidly reshaping the U.S. technology industry, with major companies accelerating workforce reductions.
Nearly 100% of patients surveyed say they’d want to know when AI is used in imaging
Researchers recently sought to better understand how patients perceive rapidly evolving advancements in AI, sharing their findings in RSNA’s Radiology.
June research roundup: 6 cool science stories we almost missed
Also, the science of poop's distinctive shape, boron buckyballs, and the secret to a soccer feint.
GTA VI May Be Limited to 30 FPS on Current-Gen Consoles
With the launch of Grand Theft Auto VI rapidly approaching, rumors surrounding the game's launch have been circulating, with some of those predicting that the game's launch will result in a console hardware shortage, more recently, however, Digital Foundry predicted that the new GTA game may not be ...
USA TODAY PLAY and Marvel debut new 'Spider-Man TODAY' comic
The Daily Bugle isn’t the only newspaper that’ll give you a fill of Spider-Man on a regular basis.
Netflix and Superheroes Are Having a Rough Stretch on Streaming....
(Welcome to my weekly streaming ratings report, the single best guide to what’s popular in streaming TV and what isn’t. I’m the Entertainment Strategy Guy, a former streaming executive who now analyzes business strategy in the entertainment industry. If you were forwarded this email, please subscribe to get these insights each week.) I have a quick prediction before we start today’s article: You might see this data in future news articles. Not my specific charts or analysis, but the core trend I’ve been monitoring—Netflix is having a lackluster Q2—will become inescapable. Often, folks want to know “What does the data say?” Well, that’s what it says. I haven’t seen this analysis hit the trades really yet, but I have a feeling some other outlets are going to start making this case soon. Remember, you read it here first. You probably have read about the problems facing superhero films at the box office this weekend. Well, this week, I explore whether superheroes are dying on TV as well! And the data says: definitely maybe! We have a lot to cover in today’s Streaming Ratings Report, which covers the two weeks of 18-May and 25-May. Today, I’m just looking at TV, like Netflix’s disappointing Q2, superhero shows underwhelming, a few TV shows dropping off the charts, The Pitt finally ending its epic run on the viewership charts (and whether “view counts” change its status as one of the biggest shows of all time), all the flops, bombs and misses, and a whole lot more. Tomorrow, I’ve got a great rundown of the film side of things. Let’s dive right in! (Reminder: The streaming ratings report focuses on the U.S. market and compiles data from Nielsen’s weekly top ten viewership ranks, Luminate’s Top Ten Data, Showlabs, TV Time trend data, Samba TV household viewership, company datecdotes, Netflix hours viewed data, Google Trends, and IMDb to determine the most popular content. While most data points are current, Nielsen’s data covers the weeks of May 18th to May 31st, 2026. You can find a link to my terminology here.) Subscribe Television - Netflix’s Q2 Slump Continues Having analyzed streaming ratings for going on half a decade, I have learned to trust my gut, but I’m always relieved when I can find actual data to back it up. For example, after a string of very popular shows like Stranger Things, Bridgerton, The Lincoln Lawyer and The Night Agent came out, week after week, in January and February, my gut wondered if Netflix had enough new and returning TV shows to sustain them throughout the year. Since then, Netflix’s post-March slate of shows has not impressed me. This week seemed to feature a potential new hit, but then, like a classic Duffer Bros. TV show, there was a twist. I speak of The Boroughs, Netflix’s latest (and last) Duffer Bros. produced show. The pitch is “Stranger Things with older actors”. And it topped the Nielsen charts: With just two weeks of viewership, The Boroughs would have been a top 25 debut show last year: But here’s the twist: Netflix has already cancelled The Boroughs! What happened? Likely a few things. First, the show didn’t do as well globally as it did in the US. As What’s on Netflix showed, it lagged behind several other shows that got cancelled. Second, its completion rate was likely low; after an initial burst of interest, it quickly dropped off on the Samba TV and Luminate charts. Third, the Duffer Bros. left Netflix for Paramount, and that may have factored into Netflix’s decision here. (Though I tend to believe that if a show is doing well, Netflix would have kept greenlighting seasons.) Still, just because I can explain why Netflix may have cancelled this show doesn’t mean I’m justifying it. In particular, as I’ve noted before, Netflix is losing a lot of their bigger shows as they reach their natural ends, and they need to replace those shows. This show had the hallmarks of a big new genre show, and it’s their biggest hit of the last few months (in the US at least), but now it’s done. Netflix’s other show this week—The Four Seasons, the second season of the “hit” show from last year—definitely disappointed. Its sophomore season had about half the viewership of the first, only 12.7 million hours. It also only had a two week run on Samba TV, and its numbers were all down on Luminate too. In other words, even with two successes, the Q2 slump for Netflix looks real: I could add to the list of disappointments: Both Lord of the Files and Man on Fire had short runs on the Nielsen charts. Running Point’s sophomore season also opened to about half its viewership, similar to The Four Seasons. A Good Girl’s Guide to Murder’s second season—see below—didn’t even make any of the three viewership charts I track, unlike the first season. Netflix is absolutely having a dismal second three months of 2026. If this Nielsen data is any indication, and I think it is, I think this will show up in Netflix’s engagement report, and maybe even their financial outcomes. And the rest of June doesn’t look much better. We have two hit shows coming back—Sweet Magnolias, one of their quietest big shows, and Avatar: The Last Airbender, a big hit for them in 2024—but the other big swings are limited series crime thrillers i.e. no future season potential. Like I said above, sometimes when I uncover a juicy nugget like this, other outlets end up writing very similar articles mimicking the data without credit. We’ll see if that happens this time! Share Television - The State of Superhero Shows on Streaming When I first heard the pitch for Spider-Noir—a Sony TV show on Prime Video that binge-released eight episodes first on MGM+ then on Prime Video two days later—I had my doubts. It’s a live-action Spider-Man show set in the 1930s, starring Nicholas Cage, based on a cameo of a character in Spider-Man: Into the Spider-Verse. No, seriously, that’s the pitch. That could either go terrifically well or horribly wrong. Great because, Spider-Man. He’s the biggest superhero we have. I’ve seen tracking numbers that put the new _Spider-Man: Brand New Da_y as the blockbuster of the year and initial pre-sales back that up. And yet this Spider-Noir pitch feels very esoteric. (Also, the eight-episode binge release feels very “Amazon copying Netflix” again.) So what’s the data say? And what does this say about the future of superhero shows?
AI is rewriting the political competitive landscape
Artificial intelligence is rapidly becoming a central infrastructure layer in political campaigns, reshaping how elections are financed, contested and influenced, The New York Times reports. Campaigns and affiliated political groups are increasingly investing in AI-driven tools for voter targeting, message optimization and large-scale content generation, turning modern elections into capital-intensive, technology-enabled competition. This shift is […]
AI is changing expectations for MBA graduates
While MBA job prospects are expected to remain stable in the near future, new hires will be held to higher standards inside rapidly evolving workplaces.
These fat-filled brain cells may be making multiple sclerosis worse
Scientists have uncovered a surprising clue that may help explain why multiple sclerosis (MS) progresses rapidly in some people but not others. In brain tissue from patients with severe MS, researchers found large numbers of “foamy” immune cells packed with fat droplets after absorbing damaged myelin. These overloaded cells appear to switch from helping repair the brain to fueling ongoing damage and inflammation.
The New York Knicks keep the ‘Cupid Shuffle’ stepping: Herman Fuselier
From NBA championships to the Guinness Book of World Records, Cupid shuffles on.
Supreme Court ruling on Roundup points to a confusing difference between the law and science
The Supreme Court’s ruling on Roundup shows science and law use the same word — causation — while asking different questions, writes epidemiologist.
Healthcare AI Leaders Are Rapidly Trying To Outmaneuver Skyrocketing Memory And GPU Costs
Compute power has become one of the most crucial components of the healthcare delivery cycle.
What is a doublet earthquake? The science behind twin tremors
Several of the world’s most destructive earthquakes were actually two or more tremors occurring in rapid succession
Pilots react to a Boeing 777 freighter's 'reckless' stunt over Texas
A Boeing 777 nearly clipped the ground during an unusually low flyover in Texas, a stunt veteran pilots called "reckless" and "stupid."
We have an epidemic of political violence in this country: National Review columnist
National Review columnist Caroline Downey discusses growing political violence and criticizes Illinois Gov. J.B. Pritzker for his remarks about the Chicago cross-burning incident.
We have an epidemic of political violence in this country: National Review columnist
National Review columnist Caroline Downey discusses growing political violence and criticizes Illinois Gov. J.B. Pritzker for his remarks about the Chicago cross-burning incident.
Disagreements between Supreme Court justices bubble into public view as major rulings loom
The Supreme Court is handing down major opinions at a rapid clip, but even with some of the biggest decisions yet to come there are signs of tension between the justices.
Scientists Baffled by Discovery of Rare “Pink Floyd” Spider Hidden in Home Walls - Futura-Sciences
The Birth of a “Pink Floyd” Spider Tiny, discreet, and quietly settled on urban walls, a new species of spider was recently discovered in Colombia—and christened as a tribute to the iconic rock band Pink Floyd. As part of a study published in the journal Zoosystematics and Evolution, South American...
Europe’s Deadly Heat Wave: A Jolt for Climate Action, or Just for A.C.?
Heat-related deaths and disruptions to daily life are forcing politicians to reckon, in different ways, with a rapidly warming planet.
Elroy Air to Become Publicly Traded Company via Business Combination with Inflection Point-led SPAC
Elroy Air, Inc., a leading U.S.-based technology developer of autonomous heavy-cargo drones for defense, rapid response and commercial logistics, and Columbu...
Hollywood gets into the microdrama race as mobile-first storytelling draws stars and major studios
Mobile-first serialized storytelling is rapidly becoming one of entertainment's fastest-growing businesses.
Digital-Only 'Grand Theft Auto VI' Is a Car Crash for Physical Media
Not all progress is progress.
Making Our Own Luck
We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.
Crews on scene of business fire in southwest Cedar Rapids
The fire happened at Tegeler Wrecker & Crane in southwest Cedar Rapids.
Life At The Speed Of Play Explores AI In Business
Mark Pincus advocates gamification, journaling, rapid experimentation, and AI-assisted innovation for entrepreneurs.
Moderna Science Day Highlights Expanding Potential of mRNA Platform
Provides broad overview of Company's research and early development programs expected to continue to fuel future growth Highlights validation of T-cell engager modality with mRNA-2808 in multiple myeloma, supporting rapid advancement of second T-cell ...
Stubborn, arrogant, a genius: France’s De Gaulle epic shows up the tepidity of our politics
The man who led Free France during Nazi occupation was single-minded to the point of obstinacy. But he believed in his own power to make history, says Guardian Europe writer Alexander Hurst
Online violence against women in politics: what shapes political party responses to technology-facilitated gender-based violence?
Political parties have a primary role to play in tackling online violence against women and gender diverse politicians. While the prevalence and impact of TFGBV, such as coordinated disinformation campaigns, deepfake image-based sexual abuse or trolling are well documented, many parties are still building their knowledge on how to respond effectively and have not put in place internal practices and policies that respond to the rapidly evolving, poorly regulated digital ecosystem. About the ReportIn order to promote and protect fair and democratic participation in politics, this ALIGN Report explores what political parties are doing in response to TFGBV and what factors shape their action. The findings, based on existing literature and interviews with gender and politics professionals, indicate there are three sets of factors which donors, civil society and practitioners should consider when designing action to support political parties to respond to TFGBV internally. These are: (1) gender norms; (2) socio-political environment; and (3) internal party factors.Key messagesUnequal gender norms are ubiquitous across politics, shaping expectations of leaders to be strong and assertive, and practices of political parties to uphold masculinist values and sustain cultures of silence. These often lead to weak response to TFGBV against women politicians.The socio-political context can incentivise or disincentivise action, depending on the salience of gender issues, which are increasingly weaponised. Electoral competitiveness, domestic laws (i.e. quota requirements), and even the political system or global normative frameworks influence political will to act.Internal party factors that shape responses will vary across countries and contexts, but include: structures to enforce codes of conduct, policies and reporting mechanisms on (TF)GBV, political ideology, extent of centralisation of leadership, and crucially the meaningful participation of women in decision-making positions, not least through internal women’s wings.Party responses can be seen as a spectrum, with actions falling between active discouragement to address TFGBV to commitment to transform unequal norms and practices within the party.About the ToolkitTogether with the report, this ALIGN toolkit offers gender professionals and others working on democratic strengthening a set of guiding questions and reflection prompts to identify which responses could be most effective and suitable in different contexts. These actions can complement other solutions to TFGBV, such as regulations promoting safety by design. The assessment spans a broad range of factors including: (1) different manifestations of gender norms, (2) the socio-political environment and (3) internal party structures.Key messagesPolitical parties are duty-bound to take action internally to respond to the significant threats posed to women members and candidates, including from their own party colleagues, affiliates and political peers.Existing party approaches to TFGBV can be assessed along a spectrum which ranges from active discouragement and passive acceptance to minimal response and transformative change.To generate effective and context-appropriate solutions to TFGBV, it is important to consider how gender norms shape leadership expectations and internal party practices, while also analysing the impact of the socio-political environment. While actions to support women to stay safe online are very common, codes of conduct and measures to strengthen women’s voice and power in the parties are proposed as most transformative solutions.
As Ebola cases surge above 1,000, experts say outbreak could be worst ever
Insufficient contact-tracing and the refusal of many residents to avoid contact with the bodies of loved ones killed by the Ebola virus are accelerating the epidemic.
Federal officials plan to offload some warehouses purchased for immigrant detention
U.S. Immigration and Customs Enforcement is retreating from a plan to use warehouses to hold up to 10,000 people on a single site, dropping a key piece of former Homeland Security Secretary Kristi Noem’s $38-billion plan to rapidly expand detention capacity this year.
Aspen Ideas: Health features four days of ‘big ideas’
Aspen Ideas: Health opened June 22 with remarks from experts, including two-minute big-idea summaries from seven health industry professionals. Since artificial intelligence is such an all-encompassing and rapidly expanding force, at least half of the big ideas revolved around AI.
Zendaya and Tom Holland kept their wedding quiet. Their 'Spider-Man' red carpet style is anything but.
Some of these looks shouldn't work on paper — but this is Zendaya.
New-To-Science Spider Engineers Smelly, Spring-Loaded Snares To Catapult Its Aggressive Prey
The tension in the silk of the scent-laden snare is enough to yeet ants into the spider's main web.
Watch the first-ever video of a newfound spider’s spring-loaded death trap
Scientists discovered that the Australian “ballista spider” uses a silk cone trap to catapult prey into its web, a feat of spider engineering never before observed.
Like New PlayStation 5 Slim Disc Edition Consoles Are Going for $499 for Amazon Prime Day. Blink and They Might Be Sold Out.
Blink and they might be sold out.
Outrage rescued an important ocean research program. Crucial ones remain at risk.
Senators saved a network of ocean sensors from "supreme stupidity." But other cutting-edge efforts are running out of funding, too.
'Sea of Thieves' live-action movie in the works as Xbox plans more than a dozen adaptations (exclusive)
'Sea of Thieves' live-action movie, based on the video game, in the works with Marvel filmmaker behind 'Spider-Man: Brand New Day.'
A spider new to science got an Oregon naming ceremony, and locals helped choose its name
The name means "cave spider" in Sahaptin, the Native language traditionally spoken in the area where the spider was discovered.
New-to-science spider builds trap that flings ants into the air
A spider living in the rainforests of Queensland, Australia, builds a snare trap reminiscent of a Roman-era ballista weapon that it uses to catapult green tree ants into a web 30 centimetres above
AI in Mental Healthcare Presents Both Opportunities and Challenges
Artificial intelligence (AI) technology and its applications are reshaping many domains of modern life, including how individuals seek support for mental health needs and how they receive that care. Healthcare professionals are rapidly adopting AI-based applications designed to support workflow and care delivery, streamline processes, and help expand access to services.
In Washington and Around the World, Alliances Are Rapidly Fraying | WSJ Politics Newsletter for June 22
Plus, more pool problems for Trump, and Jay Clayton remains in limbo over the post of director of national intelligence
Inspired by Eastern Iowa, Dave Rasdal pens novel ‘Clayville’
Former Cedar Rapids Gazette "Ramblin'" columnist Dave Rasdal, 73, discusses his new novel "Clayville," which was inspired by his 30-plus-year journalism career and the small towns around Eastern Iowa.
Could China’s next success story be healthcare?
A rapidly ageing population is shifting China’s technological innovation focus from manufacturing towards healthcare.
This Is All So Weird and, Frankly, Stupid
For the past several months, the photography community has been subjected to the strangest series of product launches that we've ever seen.
FULL SHOW: Inside INdiana Business 6/21/26
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Penn State earns another commitment from Class of 2028
The Penn State Nittany Lions earned another commitment from the Class of 2028 today with kicker Carter Petri.
Small Business Tech News: Verizon CEO Sends Shocking Message To Employees
AI is reshaping business: Verizon says automation cut 13,000 jobs, while SMBs use AI to boost productivity. Retail, startups, and AI providers are rapidly expanding capabilities and lowering costs.
The crazy numbers behind Turkey’s exit 🤯
Square feet epidemic in Turkey.At daybreak, the entire Turkish people woke up with a hangover.Beaten by Paraguay by the smallest of margins (0-1), Turkey is already heading out of this 2026 World Cup ...
Who is Gadi Eisenkot, the Israeli politician who could dethrone Netanyahu?
The former IDF chief of staff whose son was killed in the Gaza war is rapidly climbing in polls and betting markets, emerging as a leading contender to become Israel’s next prime minister.
Indian entertainment is structurally shifting: Anand Rathi
Omar Hinduja, Senior Analyst of Media and Entertainment at Anand Rathi, explains how India's entertainment landscape is rapidly developing - expanding its reach globally as it shifts to non-traditional media.
‘It’s keeping our doors open’: businesses see boost from data centers
Thousands of workers helping build data centers are bringing change to local businesses in Cedar Rapids.
Pow Wow showcases culture, history & entertainment
GRAND RAPIDS, Mich. (WOOD) – A big event is happening this weekend that combines culture, history, education, and entertainment. The relationship that the Nottawaseppi Huron Band of the Potawatomi …
Time, Outcomes, Adoption, Cost: The Four Metrics Redefining Digital Health
Despite rapid innovation, many healthcare organizations still struggle to translate new care models into system-wide impact.
This Ghost in the Shell keyboard makes me want to activate the hundred spidery robot fingers inside my regular fingers
Ghost in the Shell: Stand Alone Keyboard
Health leaders urged to curb aggressive AI spending
This HIMSS26 APAC speaker advises leaders to pace their AI investments despite the technology's rapid development.
Cramer's lightning round: Buy Vistra
"Mad Money" host Jim Cramer rings the lightning round bell, which means he's giving his answers to callers' stock questions at rapid speed.
70% of Americans trusted big business. Now it's 20%
Spider-Man faces off against the Hulk in “Brand New Day ”trailer: 'Didn't know you could get that big'
Run, Peter, run!
Spider-Man faces off against the Hulk in 'Brand New Day' trailer: 'Didn't know you could get that big'
Is your Peter tingle activated? Spider-Man finds himself going up against the Hulk in the newest 'Brand New Day' trailer.