SCROLL NEWS / DISCOVERY
Search headlines
Find the stories shaping the conversation.
Results for " BA " 97,110 found 🔀 AI-powered Shuffle
Science diplomacy, research and global health
Nature Microbiology - As a young scientist from the global south, engaging in science diplomacy has brought greater purpose and meaning to my career, writes Delfina Fernandes Hlashwayo.
Alcaraz eyes clay court season after early Miami exit
World number one Carlos Alcaraz remained confident his game is improving despite a third-round exit at the Miami Open, and after a few days to reset he'll be turning his attention to the clay court season.My mind right now is to take some days off, to reset my mind, reset the batteries, be ready and in good shape for the clay season."
Locally-based behavioral health group to open first Louisville office
The location will provide individual, couples and family therapy.
Analyst reveals high expectations for 49ers after free agency spree
Could the 49ers really challenge in 2026?
Hackaday Links: March 22, 2026
On Friday, Reuters reported that Amazon is going to try to get into the smartphone game…again. The Fire Phone was perhaps Amazon’s biggest commercial misstep, and was only on the market…
Luke Doncic facing suspension as Lakers oppose playoff-bound Pistons
The Los Angeles Lakers barely kept their winning streak alive on Saturday. They'll go for 10 in a row when they visit the Eastern Conference-leading Detroit Pistons on Monday.
Sunday Sports: Sackets hoops in the state finals, plus updates on SU sports
Here’s a recap of your North Country sports this Sunday.
Man Born with ‘Butterfly Syndrome’ Is Fighting for Change for ‘the Worst Disease You’ve Never Heard of’ (Exclusive)
Ohio resident Shane DiGiovanna, who has the rare disorder epidermolysis bullosa (EB), is advocating for legislation to help cover costly medical bandages for patients with the disease, which is also known as ‘butterfly syndrome.’
Business closed after new Ohio law banning intoxicating hemp products went into effect
Senate Bill 56 grants law enforcement the authority to remove intoxicating THC products from unlicensed retail locations,
Why Have Patriots Not Done More To Address Pass Rush?
The New England Patriots had just 35 sacks last season, ranking near the bottom of the league in the regular season.
Former 'Bachelorette' star James Taylor re-arrested on assault charges in Texas
Former 'Bachelorette' star James Taylor has been re-arrested in Texas in connection to his 2024 assault case.
The Cowboys are making a mistake with this move
The Cowboys still have to find help at linebacker.
UFL team signs former Alabama high school, Crimson Tide QB
The Thompson High School alumnus had been scheduled to play in the Indoor Football League on Sunday.
Former acting ICE director under Obama shares concern about ICE airport deployment
Cockroaches with smart backpacks? Scientists turn insects into cyborgs to detect hidden pipeline leaks
Science News: Although the concept seems like something from science fiction, science is rapidly adopting it. Researchers have started creating ‘cyborg cockroaches,.
Would you fart for science? Slap you with Science 3-22-2026
‘We’ve got some unfinished business’: Corey Gipson reflects on historic Austin Peay season
Austin Peay men's basketball head coach Corey Gipson recently reflected on his 2025-26 season and revealed what makes Clarksville special.
CBS analyst picked against Purdue basketball. Here's what he thinks of Sweet 16 vs Texas
Boilermakers fans were critical of Seth Davis for his pick proven wrong after Purdue beat Miami. Here's what he thinks of the Sweet 16 game vs Texas.
The OG Four-Door Porsche Sports Sedan Wasn't Even Built By Porsche
In 1967, a Texas-based car dealer wanted a four-door Porsche 911 S. Porsche wouldn't make it, so he turned to coachbuilders for help.
Chappell Roan pushes back after soccer star Jorginho alleges his daughter was mistreated
Chappell Roan pushes back after a Brazilian soccer player says a guard mistreated his young daughter at a hotel. Jorginho says his 11-year-old recognized Roan at breakfast in São Paulo and got...
Nevada Wins Temporary Ban on Sports Betting on Kalshi
The prediction-market platform must obtain state gambling licenses and prohibit users under 21 to offer such contracts, a state court said.
The Times' top 25 high school baseball rankings
St. John Bosco and Sherman Oaks Notre Dame remain unbeaten in high school baseball
'Disgusting.' Democratic senator slams Trump's reaction to Mueller's death
Sen. Chris Murphy called President Donald Trump's response to the death of Robert Mueller "disgusting."
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
Syracuse finalizing Gerry McNamara hire: Siena coach helped lead Orange to 2003 national championship
McNamara just finished guiding Siena to the NCAA Tournament, where it almost upset No. 1 Duke
Syracuse reportedly targeting former player Gerry McNamara as its next men's basketball coach
Buffalo Museum of Science celebrates 50% completion of upcoming Science Stadium Exhibit
The Buffalo Museum of Science marked a major milestone in its $3 million Science Stadium exhibit, announcing on March 20 the project is now 50% complete ahead of its planned
LISTEN LIVE: Supreme Court considers late-arriving mail ballot laws in case that may affect midterms
The trope of ‘choosing pets over people’ is not new
Letter: The problem isn’t the beaver on the banknote – it’s a politics that no longer recognises what holds value, writes Dr Michael J Richardson
Breaking down Bills’ selections in latest NFL mock drafts
According to the latest NFL mock drafts, the Bills could go wide receiver, linebacker, safety, or defensive linemen at pick 26.
Kathryn Wylde on the business climate in New York City and raising taxes
Bucket hats and home run chains: Getting decked out for baseball season at Poor Boys Sports
From shirts featuring new players to hats in every color, Poor Boys Sports has all your Orioles merch needs for Opening Day.
2026 NCAA Men's Basketball Tournament Highlights: Round of 32 Continues
The 2026 NCAA Men’s Basketball Tournament continues with the Round of 32 on Sunday, and we've got you covered with all the highlights!
Everything you need to know about the ‘Hannah Montana 20th Anniversary Special’ — How to watch, premiere time, who’s coming back and more
Sweet niblets! Hannah Montana is back for an anniversary special. Here's what to know.
Far-left activists stay in 5-star Cuban hotel as island suffers total blackout
CodePink sponsored flights to Cuba to protest President Donald Trump's sanctions, but the group faced backlash for staying in luxury hotels.
Chiefs’ 2026 NFL Mock Draft roundup after NFL Free Agency
A closer look at the Chiefs’ 2026 mock draft outlook after free agency, with linked to edge help, cornerback, and offensive line support.
Home health aides epitomize a key problem in the current job market
About 4 million people were employed as home health and personal care aides in 2024. They earn just $16.78 an hour, despite the need for their services being intense.
Tom Steyer explains why he should be California's next governor
Tom Steyer sat down for an interview with California Politics 360 for a wide-ranging conversation on his run to be the state's next governor.
Team USA flag football team should consider these 12 NFL stars ... but not Tom Brady
These NFL players should consider making a run at Team USA inclusion in order to earn the first football gold medal in Olympics history.
Introducing the 2026 Northeast Arkansas Outstanding Business Awards finalists - Talk Business & Politics
For several weeks, we have been soliciting the region’s business community for nominations for our first recognition program of the year: the Northeast Arkansas Outstanding Business Awards, presented by Arvest...
‘You lose yourself’: inside the mental health crisis hitting gen X women
My generation had great role models, free university and the morning-after pill. We should be running the world. Instead, two-thirds of us are facing mental health problems – and it’s not all about the menopause
This CEO took legal advice from ChatGPT to avoid paying $250 million bonus. It backfired
The court stressed that company executives are expected to exercise independent judgment, not outsource good-faith decisions to an AI.
California sheriff seizes 650,000 ballots in defiance of state officials over election count dispute
Riverside County Sheriff Chad Bianco seized over 650,000 ballots to probe alleged excess votes in California's Proposition 50 special election.
If Mike Johnson Goes, Who Runs House GOP?
The possibility of losing the majority in the midterms has put the Republican spotlight back on Steve Scalise, Jim Jordan and Tom Emmer.
Bash: Trump celebrating Mueller’s death ‘not a surprise, but that doesn’t make it okay’
American football takes for ever. In which other sports do you spend most of your time not playing the game?
The long-running series in which readers answer other readers’ questions on subjects ranging from trivial flights of fancy to profound scientific and philosophical concepts
‘Project Hail Mary’ Author Andy Weir Bases His Blockbusters in Science
The bestselling writer and self-described “dork” explains how he crafts upbeat space-set thrillers from dire scenarios only expertise can solve.
School politics class: Biggest Nato allies reject Donald Trump’s Hormuz armada demand
Global governance
Sebastian Kehl exits role as Borussia Dortmund sporting director
Borussia Dortmund sporting director Sebastian Kehl is leaving the team with immediate effect as the club undergoes a major shakeup after what will be a trophyless season.
Drew Barrymore says talk show audience member once criticized her dating profile
Drew Barrymore is remembering the time an audience member on her talk show gave his honest thoughts about her dating profile: 'I would probably run away.'
It's not just vaccines — parents are refusing other routine preventive care for newborns
Doctors are alarmed that skepticism fueled by rising anti-science sentiment is increasingly reaching beyond vaccines to other proven, routine, preventive care for babies.
The best seafood restaurant in every state, according to Yelp
Yelp picked the best seafood restaurant in every state based on customer reviews.
How iNaturalist app users have fun while aiding science
Bucs facing a tough decision with Baker Mayfield in 2026
The Bucs have to get the contract situation with Baker Mayfield solved sooner rather than later.
Nashormeh N. R. Lindo wears colorful dress to Oscars after-party
Lindo attended the after-party with her husband and supporting actor nominee for "Sinners," Delroy Lindo.
Cuba Says Its Military Is Prepared as Trump’s Threats Multiply
A senior Cuban official said the country is preparing for a possible military assault as President Donald Trump increases economic pressure on the government in Havana and suggests it could be the next US target after Venezuela and Iran.
Raptors, Suns playing for postseason in season's final stretch
Two of the best turnaround stories in the NBA this season belong to the Toronto Raptors and the Phoenix Suns, who each missed the playoffs a year ago.
Oscar-Winning Alumnus Returns to Pasadena’s ArtCenter for Entertainment Design Expo
One week after winning the Academy Award for Best Animated Feature, KPop Demon Hunters co-director Chris Appelhans returns today to ArtCenter College of Design, the Pasadena campus where he studied illustration, for the college’s third annual Entertainment Design Expo. The expo, known as ENTX, opens the Hillside Campus to the public for a full day of gallery exhibitions, game playtesting, animation screenings and interactive experiences featuring work from more than 200 ArtCenter students and alumni. General admission is free with advance registration. Two industry panels — including Appelhans’s talk — require $15 tickets. Appelhans, who graduated from ArtCenter with a bachelor of fine arts in 2002, co-directed KPop Demon Hunters with Maggie Kang. The animated film, produced by Sony Pictures Animation and released on Netflix, became the streaming platform’s most-watched film in history, according to Netflix, and swept awards season with wins at the Golden Globes, the Annie Awards and the Grammys before taking the Oscar on March 15. His talk and audience Q&A is scheduled from noon to 1 p.m. in the Ahmanson Auditorium. Doors open at 11:30 a.m. The film’s ArtCenter ties extend beyond its co-director. Art director Angela Sung, cinematographer Gary H. Lee, visual development artist Celine Kim and painter Simon Baek are all ArtCenter graduates who worked on the production, according to the college. The free portions of ENTX include a concept design showcase, a production design gallery, a model gallery, a stop motion studio preview, an alumni gallery and a KPop Demon Hunters fan art gallery. Visitors can also playtest games designed by ArtCenter students. An Animation Shorts Showcase runs from 2 to 3 p.m. and includes “Boy, I’m Scared,” a capstone short by ArtCenter graduate Lindsey Tenaglia that was named a semifinalist for the 2025 Student Academy Awards in the animation category. Also screening
Acuff scores 36 as Arkansas holds off No. 12 seed High Point 94-88
Two of the highest-scoring teams in the nation combined on a back-and-forth affair that featured 15 lead changes and six ties.
Titans sign ex-Browns linebacker
The Titans have signed former Browns linebacker Mohamoud Diabate to a contract after he wasn't tendered as an RFA.
‘The Comeback’ took on Hollywood long before ‘The Studio.’ Now, Valerie Cherish will have her curtain call
“The Comeback” was by no means the first series to hold a funhouse mirror up to the entertainment industry, but the comedy starring co-creator Lisa Kudrow, which returns for its final season on Sunday, has certainly always done it in its own navel-gazing yet endearing way.
Scientists discover surprising brain trigger behind high blood pressure
Scientists have uncovered a surprising brain-based trigger for high blood pressure, tracing it to a small region in the brainstem that normally controls breathing. This area, which kicks in during forceful exhalations like coughing, laughing, or exercise, also appears to activate nerves that tighten blood vessels—raising blood pressure. When researchers switched off this region in experiments, blood pressure dropped back to normal, suggesting it plays a direct role in hypertension.
This floating time crystal breaks Newton’s third law of motion
Scientists have created a new kind of time crystal using sound waves to levitate tiny beads in mid-air. These particles interact in a one-sided, unbalanced way, breaking the usual rules of motion and creating a steady, repeating rhythm. The system is surprisingly simple yet reveals complex physics with big implications. It could help advance quantum computing and deepen our understanding of biological timing systems.
Scientists twisted a mysterious superconductor and got a shocking result
A decades-old superconducting mystery just took a surprising turn. Strontium ruthenate, a material that conducts electricity with zero resistance at low temperatures, has long puzzled scientists with hints of an exotic, complex superconducting state. But by carefully twisting and distorting ultra-thin crystals, researchers found something unexpected: the material barely reacted at all. This challenges years of assumptions and suggests its behavior may be far simpler—or far stranger—than previously thought.
I left Goldman Sachs to build a small baking business. Here's how my time at the firm is giving me a leg up.
“Let’s get ourselves back to Fort Worth, but take care of business at hand,” LSU after loss in Tulsa
LSU Gymnastics’ Sophomore Kailin Chio and Head Coach Jay Clark spoke to the media following a third place finish in the 2026 SEC tournament in Tulsa, Oklahoma. Tiger fans came into the BOK Center hopeful for a victory due to having a podium setup, which LSU seems to have thrived on in the past. Which...
German club Borussia Dortmund parts ways with sports director Kehl
German football club Borussia Dortmund said on Sunday it is ending its collaboration with sports director Sebastian Kehl with immediate effect.
NFL draft injury analysis: Caleb Downs, S
Caleb Downs medical report
Boys' basketball coach of the year: Mike LeDuc of Damien
The second-winningest coach in California high school history guided Damien to the state Division I championship.
In Maine’s marquee Senate primary, Janet Mills reaches out to women by raising Graham Platner’s online past
Janet Mills and her allies are counting on a gender gap to narrow Platner’s wide lead ahead of the June 9 primary to decide who will face incumbent Republican Sen. Susan Collins. They are betting that the unfiltered style that has brought Platner widespread attention as someone who could help Democrats reach young men will backfire with women.
Inflatable homes on the Moon? Scientists reveal how humans could live there sooner than expected - Futura-Sciences
How could humans live on the Moon? Although the Artemis program has taken a more cautious approach following recent delays, the goal remains the same: send astronauts back to the lunar surface. Doing so will require systems that allow crews to stay there for several days, or even several weeks....
Girls' basketball coach of the year: Alicia Komaki of Sierra Canyon
She came up with a winning formula to defeat Etiwanda and No. 1 Ontario Christian in the Southern Section Open Division championship.
The Times' 2025-26 All-Star boys' basketball team
A look at the Los Angeles Times' 10-member All-Star boys' basketball team for the 2025-26 season.
The Times' final top 25 high school boys' basketball rankings
Sierra Canyon, the state Open Division champion, finishes No. 1 in The Times' final 2025-26 high school boys' basketball rankings.
Dynamax Regice Max Monday: Event Guide
Max Monday features a different Pokémon in power spots for the whole day. Regice Max Monday takes place on March 23rd, 2026. This Max Monday is the fourth March Pokémon, and it is the debut of the legendary Ice Pokémon Dynamax Regice! Dynamax Regice is a Tier 5 Max Battle in Pokémon GO. It will cost […]
Southland girls' basketball final rankings for 2025-26 seaosn
A look at the top 20 high school girls' basketball teams in the Southland, led by Open Division state champion Ontario Christian.
Former, current NBA players sound off on NBA expansion as vote looms
The NBA is moving closer towards expanding to Las Vegas and Seattle. Here's what players think about the move.
U.S. health care system is beyond repair
Letters to the editor for Sunday, March 22, 2026
FYI BR: Here are the upcoming Holi and Easter festivities in Baton Rouge
Plan for pictures with the Easter Bunny, festivities at the LSU Rural Life Museum and more.
How investors use the BRRRR strategy to scale real estate portfolios
"My strategy is basically to use every property to fund the next one," said one real estate investor.
Duke vs Baylor predictions, picks, odds for NCAA Tournament Second Round
Our March Madness experts pick the winner for No. 3 Duke vs No. 6 Baylor in the 2026 women's NCAA Tournament on March 22
Where to watch Duke vs. Baylor in March Madness Second Round: Time, TV Channel
The No. 3 Duke Blue Devils face the 6 Baylor Bears in the Second Round of the women's NCAA Tournament. Here's how to see all the action.
Rising health costs push some middle-aged adults to skip the doc until Medicare
Adults ages 50 through 64 saw health care costs skyrocket after Obamacare subsidies faded. Now some are delaying care until Medicare kicks in.
'Love Story' is Gen Z's analog dream life
The unplugged lives in "Love Story" feel remarkable to Gen Zers today. They're nostalgic for a time they don't even remember.
The Supreme Court Could Make it Harder to Vote by Mail in the Midterms
The Republican National Committee wants to toss ballots arriving after Election Day. Critics say thousands of votes — a majority cast by Democrats — are at stake.
Does the Crimson Desert AI art controversy matter?
Gamers debate as more AI accusations emerge.
What time is Michigan women's basketball's second round game?
Michigan cruised to a blowout victory over Holy Cross in their opening NCAA Women's Tournament matchup. See who they play next.
49ers News: 25 more Sundays until NFL football is back
Your daily San Francisco 49ers news for Sunday, March 22nd, 2026
Chivas hold off Monterrey’s comeback to get another win
Chivas defeated Monterrey by a 3-0 score in match defined by the last play of the match.
A Grip on Sports: In a season when Gonzaga's defense was the driving force behind its success, the Zags couldn't get the one stop they needed
A GRIP ON SPORTS • After all the flotsam and jetsam is swept away, sometimes a college basketball game, an NCAA Tournament game, comes down to making one play. Saturday night in Portland, Texas did. And Gonzaga’s season once again fell short of its ultimate goal.
Barricade That Kept Out the Far Right in France Is Crumbling
Franck Leclere made his way through the timber-framed houses of Chalons-en-Champagne and joined a crowd of people in symbolic white shirts to demonstrate against the rise of the far right in France.
'Heartbreaking' - fighter pay debate laid bare at UFC London
The debate around fighter pay reemerges at UFC London amid some career-defining performances on the undercard.
OPEN THREAD
The Daily Merengue is a place where you can feel free to discuss all things football. Do not be alarmed by the overt RMCF bias. It’s in the name! Shoutout to the mods who do a fantastic job Kung_Fu_Zizou, Juninho, NeRObutBlanco, Felipejack, Ezek Ix and yours truly, Valyrian Steel. Gameday!! Huge clash in the context […]