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Baker Mayfield extended by the Bucs
Baker Mayfield is staying Tampa Bay beyond 2026.
The Nuggets have officially signed DeMar DeRozan …
The Nuggets have officially signed DeMar DeRozan …
All North Carolina student IDs will have mental health resources printed on them as part of the Student Helpline Act
RALEIGH, N.C. (WNCN) — Today is 988 Day, a nationwide event dedicated to promoting mental health support and suicide prevention through the 988 Suicide & Crisis Lifeline, and now, in North Caro…
D-backs @ Royals discussion
Today’s Lineups DIAMONDBACKS ROYALS Lars Nootbaar – DH Carter Jensen – C Ketel Marte – 2B Bobby Witt – SS Gabriel Moreno – C Vinnie Pasquantino – 1B Geraldo Perdomo – SS Salvador Perez – DH Corbin Carroll – RF Michael Massey – 2B Nolan Arenado – 3B Nick Loftin – 3B Tommy Troy – […]
Connect at Clyde event fosters networking opportunities with business leaders
It was all business today at Clyde Iron Works for a luncheon, to talk networking and opportunities.
Why Kayshon Boutte could be immediately fantasy football relevant
Boutte will be making plays alongside Nico Collins
The 98 Biggest TV Show Flops, Bombs and Misses in the First Half of 2026
(Welcome to the Entertainment Strategy Guy, a newsletter on the entertainment industry and business strategy. I write a weekly Streaming Ratings Report and a bi-weekly strategy column, along with occasional deep dives into other topics, like today’s article. Please subscribe.) In July, I updated my look at how the “streaming bubble” popped since 2023, showing the decline in streaming TV shows over time. But after compiling and analyzing and writing about over one hundred TV show flops in the first half of 2026—I counted 99 “nominees” and there are even more honorable mentions—I couldn’t have told you that the number of shows is going down. When it comes to scripted, English-language TV shows, it feels like we have as many bombs as ever. I don’t keep a specific count, but some streamers probably had as many flops as they’ve ever had.1 That’s right, it’s time for part two of my analysis of the biggest flops, bombs and misses on streaming in the first half of 2026. Two weeks ago, I took a look at films. Today, TV shows. If you want to read the full methodology for how I assemble this list, you can find it at the bottom of this article. In short, this list is… ...scripted and unscripted TV shows,...from the nine major streamers,...in the US (using US-only ratings),...excluding true crime, kids and foreign-language shows,...that got no/poor ratings,...from Jan-2026 to the end of June-2026. Reminder: this article does not represent my personal opinion—many of these shows are great!—but I follow the data, and a miss is a miss and a bomb is a bomb. Also, price matters. If a TV show costs north of $100 million, it needs to get lots and lots of streaming viewership to justify that budget. As with past editions, I ordered this list by streamer, going from best (fewest flops) to worst (the most misses)—taking the size of the flops into consideration—and like the last edition, three or four streamers vied to take the win/loss of having the most flops. (But the actual winner is no surprise.) I try to avoid tooting my own horn too much, but seriously, in just under 5,000 words (including the methodology section) I provide a mostly comprehensive overview of the eight major streamers (Netflix, Disney+, Prime Video, Hulu, HBO Max, Peacock, Paramount+, and Apple TV) for the first half of the year, mentioning most of their hits and all their misses. It summarizes the entire first half of 2026! If you want to support this work, please subscribe. Subscribe Tubi Big Mood Boarders The Freak Brothers Twenty Twenty Six Honorable Mentions: Busted on Bodycam, Deestroying the Pitch, Destination World Cup 2026 I don’t think that Tubi spends all that much making or (mostly) licensing these original TV shows—Big Mood, Boarders and Twenty Twenty Six all come from the UK—but they’re not free and they didn’t chart anywhere. Winner: The Freak Brothers Have you even heard of this show? It’s an animated comedy...that’s on its third season! And Pete Davidson, Woody Harrelson, John Goodman and Tiffany Haddish all provide voice talent for it. Yes, animated shows don’t cost as much as live action shows, but cheap isn’t free! So a show with this level of talent needs to perform better. Disney+ Daredevil: Born Again Star Wars: Maul – Shadow Lord Honorable Mentions: Behind the Attraction, Donna Hay Coastal Celebrations, We Call It Imagineering Disney+ doesn’t make all that many original shows anymore. They had two flops, and one was animated. Their one not-a-miss show, Wonder Man, got just good enough viewership to not be considered a “miss”...but it’s since been cancelled. At this point, Disney has pivoted entirely away from making big budget TV shows for Disney+ to making...almost nothing for Disney+? Sure, Disney’s spending circa 2019-2022 was unsustainable, but now they’re pivoting too far in the other direction. At some point, Disney needs to stop shifting strategies so wildly. Really, Disney should have made fewer shows for Disney+ at launch and the shows they did make at that time needed to be made at more reasonable budgets. And they should adopt that strategy now. Winner: Daredevil: Born Again Daredevil, the Marvel Comics character, is on my personal Mount Rushmore of favorite superheroes, so it pains me to give him the win/loss today, but this show deserves it. I’ll repeat my hot take from last spring: “Based on his popularity, Daredevil should be in movies, and probably ones that cost a lot less than the MCU’s usual price tag. Disney/Bob Iger/Ike Perlmutter (who, based on reporting, made the decision) made a huge mistake selling TV shows to Netflix in the 2010s, thus limiting this character to the small screen. Daredevil could have anchored Marvel’s post-Infinity War plans, and if he did, the MCU would probably be in a better place than it is now.” HBO Max We’re just getting started with this issue, but the rest is for paid subscribers of the Entertainment Strategy Guy, so if you’d like to find out… What four streamers had the most misses... HBO’s strong start to 2026… The caveat to Peacock’s turnaround this year... Paramount+’s key man problem… What country isn’t delivering hits for Netflix or Hulu... The cavalcade of stars on a streamer where no one is watching their shows... Across nearly 5,000 words of analysis… And a lot more... ...please subscribe! We can only keep doing this great work with your support. If you’d like to read more about why you should subscribe, please read this article about the Streaming Ratings Report, why it matters, why you need it, and why we cover streaming ratings best.
Broncos host 2 linebackers and 2 safeties for tryouts
The Broncos brought in four free agent defenders for tryouts on Tuesday.
CBS Sports changes Florida bowl projection after Week 1 win
CBS Sports projects Florida to the Birmingham Bowl against an ACC team after the Gators’ 45-point season-opening win over FAU.
Hornets sign former Utah Jazz standout to Exhibit 10 contract
The Charlotte Hornets signed former Yale guard Bez Mbeng to an Exhibit 10 contract.
NFL confirms Puka Nacua is playing in Rams' season opener
Rams receiver Puka Nacua, who allegedly bit a woman on the shoulder during on New Year's Eve, will play in the Rams' opener, according to the NFL.
Ex-Chiefs OL sounds off on speculation surrounding Josh Simmons
See what ex-Chiefs star Mitchell Schwartz had to say about the speculation surrounding Josh Simmons as KC prepares for its matchup against the Broncos
Pritzker-backed PAC plans to bankroll anti-Trump candidates nationwide
The committee, called “Ready for the Fight” in reference to a line from Pritzker campaign speeches, launched today.
One Small Step: Sheriff and nonprofit leader discuss parenting amid political backdrop
Matt Carr and Stefani Wells recall their earliest political experiences and how that has shaped them today, as parents.
Week 1 injury report for the New England Patriots
The Patriots have published their Week 1 injury report.
TreVeyon Henderson ruled out for Week 1
TreVeyon Henderson will not be in the lineup for the Patriots in Week 1.
Villa take 'big step forward' with win over Brugge
Unai Emery said Aston Villa took "one big step forward" after clinching their first win this season with a 3-2 victory at Club Brugge in their Champions League opener on Tuesday."We took one step forward today and it was very, very important for our confidence and stability," Emery said.
Apple Releases Firmware Update for 140W USB-C Power Adapter
Apple today released a firmware update (version 1.4.90) for its 140W USB-C Power Adapter. It is unclear what is included in the latest firmware, as Apple does not publish release notes for this. The update will be installed automatically over time when the power adapter is plugged in and connected to a Mac or other device. The update will be installed automatically over time when the power adapter is plugged in and connected to a Mac or other device.
Florida high school football coach fired after just three games
Dan Nieboer was hired away from Jason Witten's Liberty Christian staff in Texas to lead Lely (FL). After an 0-3 start, he's been let go.
49ers catch massive break for Week 1 battle vs. Rams
The 49ers are taking on the Rams in Week 1 of the 2026 season, but their division rivals won't have one of their best players for the matchup.
Celo to Participate in Merkle Science Meet in Washington, D.C. on September 8th
Celo will participate in Merkle Science Meet in Washington, D.C. on September 8th at 18:00 UTC. Markus will join a panel on the GENIUS Act and the future of U.S. stablecoin regulation.Refer to the official tweet by CELO:Kicking off @thestablecon week today, @MarkusMento speaks at @MerkleScience Mee…
Shutterstock Appoints Three Accomplished Business Leaders to Board of Directors
/PRNewswire/ -- Shutterstock, Inc. (NYSE: SSTK), a family of brands delivering scalable creative and GenAI solutions to help customers fuel great work, today...
HHS Announces Key Leadership Selections at FDA to Promote Innovation, Reform, and National Health Priorities
The U.S. Department of Health and Human Services today announced the selection of four senior leaders at the U.S. Food and Drug Administration.
UND again named among region’s best places to work
Prairie Business recognition reflects workplace culture created by UND faculty and staff.
Supporting small business across North Dakota
ND SBDC State Director Tiffany Ford joins ‘North Dakota Today’ to discuss the organization’s statewide impact
AT&T Business Expands Work with Amazon Leo for Resilient Connectivity
AT&T Business has furthered its agreement with Amazon’s Amazon Leo constellation to offer “converged connectivity solutions” integrating satellite
Falcons drop 2 spots in Week 1 NFL power rankings
Falcons drop to No. 26 in The Athletic's power rankings: 'Things aren't looking great in Atlanta'
Eutelsat Wins Further Connectivity Business in Greenland
Eutelsat is going to help to bring better connectivity to Greenland. Alongside the European Union, the government of Greenland and the government of
Exclusive: Two of gaming’s biggest names are making a big investment in gaming’s future
The first thing to know about the Nova Games Foundation is that it isn’t about The Game Awards. And it’s not about PlayStation. The ambitious new grant program is the brainchild of Geoff Keighley and Mark Cerny. Keighley is the host of The Game Awards, Summer Game Fest and Opening Night Live. Cerny is a game designer of some 45 years and the lead architect for the PlayStation 4 and 5. But this new thing, which they’re revealing through Game File, isn’t about their day jobs. It’s an unaffiliated, standalone philanthropic project. It’s a bet on the artistic future of video games and a way, they tell me, to give back. “I’m nearing the end of my career,” Cerny recently told me over email. “I’m not done yet, but paying it forward—in the best way possible—is very much on my mind these days,” The Nova Games Foundation is a university-affiliated fellowship program, intended to offer six-figure grants to 20 young game designers each year, potentially for decades to come. It will offer no-strings-attached funding along with mentorship from games industry leaders, a combination intended to aid the development of groundbreaking new games, Cerny and Keighley told me. Nova will begin accepting applications in December, from class of 2026 and 2027 students from 13 affiliated gaming programs at universities in eight countries. The schools working with Nova include the New York University and the University of Southern California in the U.S., along with Abertay University in Scotland, Cnam-Enjmin in France, TH Köln in Germany, and the Royal Melbourne Institute of Technology in Australia, Cerny and Keighley said. The plan: $100,000 per recipient, with about a quarter of Nova fellows eligible for up to $500,000 more for projects that are shaping up particularly well. Payments will be delivered based on development milestones, and recipients will own their games. Nova will help promote the work, and developers will be free to pursue the publishers and platforms of their choice. Nova can help introduce fellows to publishers, but won’t take a cut. “I’ve always wanted to give back, but given my role in the industry, I’ve never felt it appropriate to commercially invest in games,” Keighley told Game File. “I’ve never owned stock in a game company or taken a financial stake in a game. Nova is philanthropy: we aren’t taking equity or looking to recoup the grants. The return we’re hoping for is creative—helping new voices make games and find their footing. “Mark and I have each made multi-million-dollar donations to establish the foundation, and we intend to keep contributing. We hope others will join us.” Cerny and Keighley have already hired an executive director, John Maconga, and a head of grants, recent Game Developers Conference director Ashley Corrigan, to help launch the effort. They’re working to recruit game industry leaders to join the effort. Keighley says “dozens of leading game directors have already expressed interest in contributing their time.” To name one, they’ve already gotten Josef Fares, lead designer from It Takes Two and Spit Fiction studio Hazelight on board with a donation and pledge to help out. “I’m proud to support Nova because it gives the next generation of creators the freedom to explore their creativity and hopefully bring their unique visions to life,” Fares told Game File. A plan forged from a friendship Keighley and Cerny have known each other a long time. It’s been so long, Cerny isn’t even sure exactly when they met. “We travel in much the same circles and I’m sure first intersected in the 90s or early 2000s,“ Cerny said. Keighley thinks it might have been during his stint writing a column about the mid-’90s console 3DO for a gaming magazine while Cerny was working on games with Crystal Dynamics or on Way of the Warrior with Naughty Dog. They became genuine friends about a 10 years ago, Keighley said, as they bonded over a shared love of games and a hope to improve the industry. “About a decade ago, we started having dinner a few times a year in LA,” Keighley said. “Just to catch up on life and the industry. Those conversations continued over Zoom during COVID. Nova grew out of that friendship and a question we kept coming back to: ‘What could we do to help the next generation of game directors get started?’” Keighley credits Cerny with the idea to figure out a way to put their money and time back into the industry. At one of those dinners, Keighley proposed the idea of a fellowship program. He’d recalled applying for a Rhodes Scholarship when he was younger. “Spoiler: I didn’t get it,” he said. He’d admired the MacArthur Foundation’s so-called “genius grants.” He liked these kinds of programs that recognized people’s talents and gave them the financial boost and the freedom to realize their potential. With Cerny, he had pondered what a game industry version of that could be. Keighley liked the idea of centering the fellowship on students, drawing inspiration from the accomplishments of Jenova Chen, the USC game design graduate who went on to lead the creation of gently moving, ambitious games such as Flower and Journey. Keighley also thought it could be useful to help promising graduates bridge the transition from student to professional. “Joining an established studio isn’t always possible—especially in today’s market—and even then, it isn’t the right path for everyone,” Keighley said. A fellowship, he realized, could give “graduates the time, resources and guidance to pursue a game of their own and not worry about the commercial viability.” As the idea took shape, Cerny also saw an opportunity to enable more games of a certain type: “The target with the grants is games as an artistic medium,” Cerny told me. “We like to say games with ‘artistic, literary and societal value.’” He added: “I’m a pretty big gamer myself, though I tend to gravitate towards the smaller and more unique or artistic titles, games like Neva, Abzu, Gorogoa, Stray or Outer Wilds. I was just playing and Roger on a flight to Japan, and was getting misty eyed to a degree that I was concerned that a flight attendant would ask me if I was OK. “So one fun benefit here is the games that will come out of the Nova Games Foundation – I can’t wait to play them myself.” Cerny believes it will also be useful for Nova fellows to hone their craft and team leadership skills. “We are looking for the next generation of visionaries,” he said. “The trick is that they will also need to have the executive function necessary to drive a small project to completion.” Game File is a reader-supported publication. To receive new posts and support my reporting, please consider becoming a free or paid subscriber. Subscribe Going big with this Keighley and Cerny may have started Nova and may be the ones primarily backing it right now, but they’re dreaming of something that goes beyond them. “Mark and I may have helped get it started, but one of our measures of success is that Nova grows into something the entire games industry feels a sense of ownership in,” Keighley said. “Our ambition is to build a lasting endowment supported by people and companies across the industry, and an equally broad community of creators willing to give their time and experience to the next generation.” The industry has a lot of knowledge that it can pass to the next generation, Keighley said: “Nova can hopefully become a way to connect that generosity with talented young creators at the moment when it can make the biggest difference.” Cerny, who told me he believes Nova can mature “over the next 10 or 20 years,” sees an opportunity to give generations of game makers momentum. “The industry has changed immeasurably since I started in games in 1982,” he said. “These graduates have talent, training and tools that outclass what we had back in the day by an astonishing amount. But they face a tough road ahead getting traction in the industry, and many could benefit from our support. We want to be there to give it to them.” “There’s a personal side to this, too,” Keighley said. “I don’t have children, and I’ve spent a lot of time thinking about what I can do for future generations. Games have been my entire career. I’ve been incredibly fortunate, and helping someone else build a life in this industry feels like a meaningful way to give back.” Cerny’s oeuvre dates back to Marble Madness and Sonic the Hedgehog 2. He has stood on stage multiple times to reveal the future of PlayStation hardware. He’s been an executive producer for a string of modern PlayStation classics such as The Last Guardian and Marvel’s Spider-Man. Nevertheless, of Nova, he said, “It’s certainly not like anything I’ve done before.” Nova Foundation applications will be due in December and the first wave of fellows will be announced in March 2027. A full list of participating universities and steps students and recent graduates can take to apply to become a Nova Fellow is forthcoming.
Aspen School District renews membership with Valley Health Alliance
Valley Health Alliance announced today that the Aspen School District has renewed its membership, marking a significant milestone for both organizations.
Berman campaign: “We’re going fishing” – ER nurse and Democrat Mitchell Berman launches first ad of general election in Wisconsin’s First District Congressional race
Spot features Berman fishing and focuses on ending corruption in Washington, contrasting Berman’s working class background and Republican Bryan Steil’s corporate special interests RAYMOND, Wis. — Today, Mitchell Berman, ER nurse and Democratic candidate for Wisconsin’s First Congressional District, launched...
MAC appealing Michigan-Western Michigan result after 'further study'
Michigan football's game against Western Michigan is in the record books as a Wolverines win.
MAC reverses course, appeals Michigan win over Western Michigan
The MAC is appealing the Michigan vs. Western Michigan game result, claiming the Big Ten used incorrect replay protocol.
Microsoft September 2026 Patch Tuesday fixes 966 flaws, 2 zero-days
Today is Microsoft's September 2026 Patch Tuesday, with security updates released for a record-breaking 966 flaws, including two actively exploited zero-day vulnerabilities.
FSU falls in USA TODAY Sports' college football re-rank
In the newest USA TODAY Sports re-rank of all 138 FBS teams, Florida State checked in at No. 50, the eighth best in the ACC.
Free Senior Fest brings health screenings, resources to Washoe County seniors Today
Senior Fest brings dozens of vendors and health services together for Washoe County seniors in Reno.
Apple Releases iOS 26.6.2
Apple today released iOS 26.6.2 with a fix for "an issue that prevents downloading a software update over a cellular connection". The minor software update is rolling out now for the iPhone 11 series and newer. To update your iPhone, open the Settings app and tap on General → Software Update. It might take a few minutes until the update is visible to everyone. iOS 26.6.2 arrives approximately three weeks after iOS 26.6.1, which delivered security fixes.
Scientists Are Still Trying To Understand How the Moon Formed
The Earth and the Moon have nearly identical isotopic compositions, and the Giant Impact Hypothesis strives to explain this. New research into the ancient impact shows how the temperature of both worlds, and how it affects the strength of the materials involved in the collision, shaped the outcome, including the isotopic compositions.
Health: The Fight For The Health Of 9/11 First Responders
A quarter century after 9/11, the health of those who responded to the attacks continues to be affected.Some 3,000 people died across three locations that day. An estimated 400,000 people were exposed to toxic contaminants and risked physical injury in the hours and days that followed. That’s according to data from the Centers for Disease Control and Prevention.Since the dust and debris have settled, more than 96,000 have been diagnosed with physical and mental health conditions related to 9/11.In 2010, President Barack Obama signed the James Zadroga 9/11 Health and Compensation Act, establishing the World Trade Center Health Program and reopening the 9/11 Victims Compensation Fund. Today, more than 150,000 people are enrolled in the program.But that program wouldn’t exist without the advocacy of survivors and first responders who put their bodies and lives on the line following the attacks. How did that fight for care unfold?For more information about the Rutgers WTC Health Program, click here. And to learn more about applying, click here.Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a.
Youth with CF on approved treatment still face mental health issues
Youth with cystic fibrosis continue to experience mental and behavioral health concerns despite treatment with Trikafta, according to a study.
SKY BLUE CINEMATIX - ENTERTAINMENT - BRAND INTEGRATION : Two Films. One Global Partnership.
Sky Blue Cinematix appointed exclusive worldwide brand-integration partner for two new features from Tested Films.London, UK, Sept. 08, 2026 (GLOBE NEWSWIRE) -- Sky Blue Cinematix, the entertainment and brand-integration division of Sky Blue Media Group, today announced its appointment as the exclusive global brand-integration partner for two upcoming feature films from Tested Films: the action thriller Habeas Corpus and the neo-noir romantic mystery Blurred. Sky Blue Cinematix appointed exclusi
Green Sports Alliance Names Jeff Pacini as New Executive Director
/PRNewswire/ -- Today, the Green Sports Alliance announced the appointment of Jeff Pacini as its new Executive Director. In this role, Pacini will steer the...
Rogers and OEG Sports & Entertainment Extend Strategic Partnership for 10 More Years
EDMONTON, Alberta, Sept. 08, 2026 (GLOBE NEWSWIRE) -- Rogers and OEG Sports & Entertainment (OEGSE), today announced a 10-year extension of ...
Reshuffled college football rankings see Oregon tumble, LSU rise in US LBM Coaches Poll
The results of Week 1 of the college football season brought major changes to the US LBM Coaches Poll. Here's how the Top 25 rankings look:
USA TODAY Sports Super 15 East region football rankings, Week 4
St. Frances Academy stays solidly at the top, but a new No. 2 makes its rise.
Eagles legend Brandon Graham announces retirement after 16 seasons
Brandon Graham announced his retirement for a second time, ending a franchise-record 16-season career spent entirely with the Philadelphia Eagles
AMP Sports Launches The Dark Side Podcast with Seattle Seahawks Super Bowl Champions Derick Hall and Byron Murphy II
SEATTLE – September 8, 2026 –Sinclair’s AMP Sports today announced the launch of The Dark Side, a new podcast featuring Seattle Seahawks Super Bowl champions Derick Hall and Byron Murphy II, alongside KOMO News Sports Director Niko Tamurian. Each week, The Dark Side will go beyond traditional game analysis, with Hall and Murphy offering a...
Week 1 fantasy tight end rankings: Top TE streamers, starts
Chicago's Colston Loveland finished strong last season and became one of the top tight ends in this year's fantasy drafts. Where does he rank Week 1?
Atlético v Sobradinho: Crias do Galo are in action today!
Atlético vs. Sobradinho – September 8 (Tuesday) – 3:00 PM🏆 Tournament: 1st round (single match) – Copa do Brasil🏟️ Venue: Arena MRV📺 Broadcast: GaloTV H2bet🗺️ Match Guide: Atlé...
The official sequel to The Ur-Quan Masters releases its free demo today
Blast your opponents in 1v1 arcade space battles like it's 1992 all over again.
How did CBS Sports grade the Oklahoma Sooners for Week 1 win?
CBS Sports awarded Oklahoma an A- for its dominant win over UTEP in the season opener.
Apple to Introduce All-New 'Readiness' App Tomorrow
Apple plans to announce an all-new "Readiness" app during its "Surprise and Shine" event this Wednesday, according to Bloomberg's Mark Gurman. In a social media post today, Gurman said the "Readiness" app will be a "variant" of the existing Vitals app on the Apple Watch. "The idea is to better compete with software from Whoop and Oura," he said.
North Dakota Today - North Dakota Small Business Development Center
recurring recording of North Dakota Today on KVLY
Mexico's star Julián Quiñones earns 2026 Ballon d'Or nomination
Julián Quiñones, the forward for Mexico and Al-Qadsiah, makes the 2026 Ballon d’Or shortlist.
If You Invested $1000 In Sphere Entertainment Stock 5 Years Ago, You Would Have This Much Today
Sphere Entertainment (NYSE:SPHR) has outperformed the market over the past 5 years by 18.95% on an annualized basis producing an average annual return of 30.39%. Currently, Sphere Entertainment has a market
USA TODAY Sports Super 25 national high school football rankings, Week 4
St. Thomas Aquinas' win over Columbus ensured Florida powers didn't shift in the Super 25, but teams from Texas and Georgia saw jumps after big wins.
Seahawks select edge rusher in latest 2027 NFL mock draft
The Seattle Seahawks select Clemson edge rusher Will Heldt in this latest 2027 NFL mock draft.
Rogers and OEG Sports & Entertainment Extend Strategic Partnership for 10 More Years
Rogers is giving away more than 1,500 tickets to customers throughout season, including 300 for Home OpenerEDMONTON, Alberta, Sept. 08, 2026 (GLOBE NEWSWIRE) -- Rogers and OEG Sports & Entertainment (OEGSE), today announced a 10-year extension of their strategic partnership, keeping Rogers Place as the home of the Edmonton Oilers through 2036. This extension comes as the iconic Rogers Place is celebrating its 10-year anniversary. To mark the occasion, Rogers is awarding more than 1,500 Oilers ti
Apple’s latest acquisition is about technology that sounds futuristic
EU filings revealed today that Apple has acquired a company called Sonera, makers of wearable-centered technology that sounds futuristic.
Deonte Banks' ex-coach: 'Everbody's gonna see' why Giants drafted him
Henry Baker, the former coach of New York Giants CB Deonte Banks, believes everyone is about to see why he was a first-round pick.
AZ's R&D chief Barr touts internal 'science success story' after IL-33 antibody's stellar showing in COPD
With a detailed data drop that AstraZeneca’s R&D chief described as an internal “science success story,” the British Big Pharma has secured an FDA priority review for what it believes could become a flagship biologic in chronic obstructive pulmonary disease (COPD). In detailed results from the late-stage Oberon and Titania trials—first teased in March and detailed in full at the European Respiratory Society Congress in Barcelona this week—the drugmaker laid out the extent of its IL-33 inhibitor’s potential to reduce moderate and severe exacerbations in a wide range of COPD patients still struggling with those “lung attacks,” as AstraZeneca’s Sharon Barr, Ph.D., called them, despite using standard-care inhaled therapy. In the headline results, a 300 mg dose of tozorakimab given once every four weeks curbed those moderate and severe exacerbations in the studies’ primary population of former smokers by 29% in the Oberon study and 34% in Titania. In the overall population of both current and former smokers, these reductions were 30% and 29%, respectively, versus placebo and inhaled standard of care. The benefits also extended to clinically meaningful exacerbation reductions in all prespecified patient subgroups and specifically turned up promising signals in patients across a range of blood eosinophil counts, with Barr telling Fierce that “it’s the details that make this even more exciting than the high-level results that we’ve already shared.” In fact, during AZ’s tozorakimab poster presentation at the ERS 2026 Congress this past weekend, attendees were so enamored by the data that event organizers had to encourage people to clear the room and look at the other presentations on offer, Barr said in an interview. “I think it really speaks to the fact that there is a lot of buzz around these data because the entire respiratory community has been so desperate for new therapies for these patients,” she explained. The respiratory disease continues to represent a “staggering unmet medical need,” Barr said, highlighting the COPD exacerbations that the Oberon and Titania studies homed in on, which she added carry a greater mortality risk than a heart attack. “When a patient has a severe exacerbation, only about half of them are still alive within three and a half years,” she pointed out. As for tozorakimab specifically, Barr christened the molecule “an AstraZeneca science success story,” harkening several years back to the point at which researchers began to explore IL-33 as a driver of respiratory disease, and COPD in particular. At the same time, “there was still so much that wasn’t understood,” she admitted, highlighting the insight that IL-33 signals through both ST2 and EGFR through the RAGE pathway, a discovery Barr attributed to AstraZeneca's own scientists. Understanding the need to tackle both pathways in COPD—and aware of competitor candidates in the hopper, including one that bound ST2—the company ultimately had to make some “courageous decisions,” Barr said. These included taking a prior COPD molecule offline and going back to the drawing board to reinvent its potential IL-33 label “to make sure that we had a molecule that could block signaling through both arms of the pathway, through both the reduced form and the oxidized form, knowing that we wouldn’t be first, but striving to be best.” “When we put [tozorakimab] into the clinic, we firmly believed that we had a differentiated molecule, and we saw the other molecules blocking just ST2 or partially blocking IL-33, unable to deliver two positive pivotal studies in COPD,” Barr explained. “We kept marching forward because we believed our molecule was differentiated, and now I think we have the clinical validation that supports that.” Ultimately, AstraZeneca finds itself on much better footing these days when it comes to potential biologic rivals to tozorakimab in COPD. Sanofi and Regeneron’s Dupixent, for instance, is approved to treat COPD exacerbations in patients with high eosinophil counts, but not low ones. Meanwhile, the future has become cloudier for other next-gen IL-33 candidates from Sanofi and Regeneron, as well as Roche, which have suffered trial flops in recent years. One other potential ingredient for AstraZeneca’s success in its duo of studies was that the company was “ambitious in the trial design, willing to look at an all-comers population,” Barr said, “and willing to enroll the most severe patients.” Prior studies for would-be biologics rivals in COPD “avoided enrolling” those patients, she pointed out. She also highlighted the Big Pharma’s painstaking design of exacerbations in its trial, which “gave us a very rigorous readout,” and pointed to “the extra effort and investment” the company put in to understand the effect of mucus plugs in patients. Barr described mucus production as a “key feature in disease diversity,” noting that mucus plugs—obstructing clumps of mucus that block patients’ airways—are associated with worse outcomes in COPD. In its data announcement, AstraZeneca noted that an integrated analysis of Oberon and Titania found tozorakimab “demonstrated a reduction in patients’ mucus plug score,” with the pharma claiming its biologic is the first to deliver such results in a broad COPD population. “So being able to reduce those mucus plugs, we expect, is an important part of driving benefit for patients who are living with COPD,” Barr said. Again touching on the breadth of the study populations, Barr added that tozorakimab “worked across all eosinophil levels in both current and former smokers across all levels of lung function,” which she suggested “really simplifies decision-making for clinicians, and it allows them to offer therapy to the broadest possible patient population.” In the highest patient eosinophil count group, tozorakimab helped chart a 43% reduction in exacerbation risk, which Barr stressed were “unprecedented data.” In the mid-level group, AZ’s drug delivered a 23% reduction and, in the lowest group, a 34% reduction in eosinophils, which Barr said suggests efficacy “in all patient subgroups.” As for AZ’s recent guidance upgrade on the medicine’s sales opportunity, the lift from a $3 billion to $5 billion range to $5 billion plus was informed by multiple factors, Barr said, including the fact that “in 2024, there were multiple competitors, and there aren’t anymore.” Additionally, “we know that this is a massive unmet medical need, and this is a really incredible set of data that we think will be very convincing to the clinical community,” Barr said. Looking ahead to a potential evolution of the COPD treatment landscape, Barr noted that most patients start treatment in the community with an option like a triple therapy, and for them, having an option like AstraZeneca’s inhaler Breztri will remain a “really important part” of that journey. But of the patients uncontrolled on triple therapy, which Barr described as “about half of them today,” just a “small fraction” are currently eligible for biologic therapy, which she emphasized AstraZeneca is working to change. Understanding that COPD is not a “one-size-fits-all” disease, AstraZeneca is also looking at its antibody drug Tezspire for patients with T2-driven disease, and the company continues to think about new mechanisms for tackling COPD through both systemic and inhaled drugs, Barr said.
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Six decades of politics (but little government)
The first aired episode of “Star Trek,” entitled “The Man Trap,” premiered on September 8, 1966 — 60 years ago today. I’m actually editing a political science fiction issue of The Forum right now, and it’s prompted to me think a lot about the ways that Trek deals with politics and government and what it’s offered us as commentary. The @smotus report is a reader-supported publication. To support this work, please become a paid subscriber. Subscribe The original TV series ran from 1966 to 1969. It had a loyal but modest following, but the audience grew substantially with the series in syndication for years after that. The franchise developed its first motion picture in 1979, followed by five sequels, and then a whole other series of films built around the “Next Generation” series that first aired in 1987. In recent decades, several more TV series have built up around it, including the current “Strange New Worlds,” now in its fourth season. Throughout the past six decades, the franchise has offered us a good many insights into US politics and international relations, although often disguised as science fiction yarns. The original series was largely a Cold War fable, with the United Federation of Planets (a stand-in for the US) perpetually at odds with the Klingon Empire (a stand-in for the USSR). The “Let That Be Your Last Battlefield” episode (1969) posited a planet divided into two races, largely indistinguishable to outsiders, but nonetheless constituting a brutal racial hierarchy. “Patterns of Force” (1968) showed a struggling planet where the leader had attempted to construct a benevolent dictatorship — literally Nazism without bigotry — and found that authoritarianism could not exist apart from hierarchy and oppression. (Relatedly, I’d put “Star Trek VI: The Undiscovered Country,” high on a list of dad films about the end of the Cold War, near “The Hunt for Red October.”) Get 20% off for 1 year Indeed, the original series itself was something of a political statement, with a multi-racial crew running the Enterprise, a diverse and largely peaceful Federation mostly free from want and oppression, and protected by Starfleet, an armed force whose scientific mission was at least as important as its military one. Famously, when Nichelle Nichols wanted to walk away from the role of Uhura on the original series, none other than Martin Luther King, Jr. met with her and urged her to remain on the show, discussing the importance of viewers seeing an intelligent Black woman as part of the command team three centuries hence. Later series in the Trek franchise offered a good deal of political commentary on their own, but probably none as explicitly and incisively as “Deep Space Nine,” which ran from 1993 to 1999. The episodes surrounding the Dominion War, especially the “In The Pale Moonlight” (1998), showed the compromises, sacrifices, and moral rot associated with winning even a just war — probably better than any series would until “Andor” (2022-25). In “Far Beyond The Stars” (1998), Captain Benjamin Sisko is somehow transplanted to the role of a science fiction writer in 1950s New York. The writer is frequently sidelined and his ideas stolen because publishers don’t want to credit a Black writer. Several series have depicted the secretive Section 31 — an unacknowledged black ops security force operating within Starfleet. These episodes often end up using Section 31 as a foil to show the dangers of a lawless group within a lawful society, even (especially) when that group posits itself as essential for everyone else’s freedom to continue. The current “Strange New Worlds” has played with a few political themes. I found the first two seasons of this show among the best that the Trek franchise has produced in decades, but this season and the last have really been struggling for ideas. Yet one interesting thread is the idea that the diplomatic and enlightened leadership style of Captain Christopher Pike will not work in all situations. “A Quality of Mercy” (2022), which I wrote about here, puts Pike in the middle of a battle with a Romulan vessel in an alternate timeline, and finds that Pike’s conciliatory style would actually make a lengthy and deadly war more likely, while a quick and more violent approach might have prevented the war. This season’s opener, “Valles Marineris,” shows a pre-lightspeed civilization locked in a war to the death with a neighboring planet. The idea of an alliance or a federation hasn’t even occurred to them — their ship’s commander is curious but doesn’t see it as an option. For a franchise as political as “Star Trek,” one thing we almost never see is the government. We get occasional glimpses of Starfleet’s council — mostly uniformed people at a rectangular table — but almost no sense of how the Federation is governed. Are there elections? Who is in the legislature? How much power does the president have? What kind of factional divisions do they wrestle with and how? The shows and films are pretty silent on this. We’ve seen a few military tribunals within Starfleet, but little about how civilians deal with crime and injustice. With recent years seeing some of the franchise’s more interesting plot lines and casts, it seems clear that Star Trek is still full of energy and ideas. Given the erosion of American democracy and the reshuffling of the international order, there’s no shortage of material for future shows to comment on. I’m not sure we should toast to 60 more years, but cheers to a show that continues to teach us about ourselves. Share
Memorial Hermann Health System Deepens Partnership with Strategic Investment in PartsSource
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