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US midterms: With deep-red states now in play, could blue wave redraw America's political landscape?
The politics of war
Israel went to the polls last Tuesday and it is the turn of the United States next Tuesday. The differences in the two elections are self-evident. Compared with the US, which has favourable geography and does everything at scale, Israel is tiny and part of an unstable region. For its elections, it has adopted an almost pure form of proportional representation based on lists. This encourages multiple parties and can make it almost impossible to form a government, as we can now see. The US system is complex in its own way but discourages third parties. Yet for all the differences in size, geography, and political systems, the fates of the two countries are closely connected. Israel has come to depend on the US to sustain its military strength, and over the past few tumultuous years that dependence has created resentment in the United States. The Biden administration was punished for appearing to give Netanyahu a blank check after the Hamas attacks of 7 October 2023, and not holding Israel back as it employed ruthless tactics in Gaza. Because of the treatment of Palestinians, American views of Israel have grown progressively more negative over the past few years. Only a third now support the Israeli government. While on the left, this is largely because of how Israeli forces have operated in Gaza and, more recently, how the settler movement has behaved in the West Bank, for the American right the issue has been about how Benjamin Netanyahu persuaded Donald Trump to forget his wariness about more Middle Eastern wars and agree to a joint attack on Iran, which has gone badly wrong. The Palestine question was not a big issue for the two large Jewish blocs in last Tuesday’s election. Both supported a tough response to Hamas after October 2023 and neither accepts a two-state solution. It was, however, the threat posed by the ethno-nationalist policies of Itamar Ben-Gvir and Bezalel Smotrich, the two extreme members of Netanyahu’s coalition, and their tolerance, even encouragement, of settler violence, that brought out the Arab voters. (In principle this should strengthen their position though to turn into real power would require the ‘Change Bloc’ overcoming their opposition to involving Arab parties. The alternatives are a National Unity government, defection from the Change Bloc to Netanyahu, or deadlock and another round of elections in the new year.) There was also broad support for the war against Iran among the Jewish parties. The difficulty here is that the objectives behind the war have yet to be met, and that continuing with military operations depends on the United States. In this way the two elections have come together at a crucial moment. If Netanyahu hoped that a victory over Iran would help him retain his majority, cementing his legacy as an Israeli war leader, it did not work out that way. Trump also expected a great victory about which he could boast. He promised at most the end of a hateful and aggressive regime, with a record of hostility to both the United States and Israel, or at least the elimination of Iran’s military capabilities and the end of its nuclear programme. Eight months on, there is not much to boast about; vital objectives remain elusive: the Iranian regime is even more hardline than before; the international economy is barely coping with the closure of the Strait of Hormuz; and Saudi Arabia is struggling with an unwanted conflict with the Yemeni Houthis. For all these reasons, the Iran War has been a dark cloud hanging over both elections. Yet the issue has been approached in different ways. Netanyahu sought to push the issue before the election while Trump has been more cautious. Trump’s essential claim is that there is nothing to worry about and he’s still working out what final steps need to be taken to provide a definitive conclusion to the conflict. Netanyahu’s final pitch was that there was lots to worry about. He focused on Israel’s dire security situation, with the Iran War unfinished and the prospect of imminent economic isolation because of international sanctions. For him it is imperative to defeat Iran decisively, and without delay. Why this different response to the same war? Part of the answer lies in how public opinion in the two countries responded to the war. In this post, I show how this came about. We await the outcome of the US midterms but know the result, at least in terms of the share of the vote if not yet the shape of the new government, of the Israeli election. With the elections out of the way Netanyahu is pressing for another round in the war. Trump is less sure. I conclude with thoughts on the importance of how he decides.
A toss-up race in Trump country mirrors a complicated midterm landscape
A close contest for one of Montana's two seats in the House of Representatives fits into a larger trend putting Republicans on defense.
First Look: Closer Than Ever to the Antiqua, the new Louis Erard x Vianney Halter Collab
The new Louis Erard x Vianney Halter collaboration captures the Antiqua’s steampunk aesthetic with an asymmetrical case and riveted portholes
Brash architect of Trump’s midterm strategy could become midterm scapegoat
Intense and self-assured, James Blair has had the president’s backing, but a major loss could set off a search for someone to blame.
More charged with voting as noncitizens in NC + DOJ to send election monitors
Read Under the Dome for a daily dose of politics news.
Bulkeley: We need to keep religion out of politics
"Never discuss politics or religion" ranks among the best advice my mother ever gave me. The two things people don't want to hear from you are your theological beliefs and your governmental philosophies.
The nation’s cartoonists on the week in politics
Every week political cartoonists throughout the country and across the political spectrum apply their ink-stained skills to capture the foibles, memes, hypocrisies and other head-slapping events in the world of politics. The fruits of these labors are hundreds of cartoons that entertain and enrage readers of all political stripes. Here's an offering of the best of this week's crop, picked fresh off the Toonosphere. Edited by Matt Wuerker.
900-plus state contractors could be subject to 'money out of politics' plan
LANSING - A ballot proposal before voters in the Nov. 3 election could ban more than 900 businesses and nonprofits from contributing to Michigan political candidates, according to state contractor data reviewed by The Detroit News.
CU Boulder professor Steve Nerem to co-chair NASA survey | ETIH EdTech News
University of Colorado Boulder professor Steve Nerem will co-chair NASA's 2028–2037 Earth science decadal survey, reviewing satellite capabilities and more than 250 research submissions. ETIH edtech news covers the appointment and the university's role in space research.
Bird flu detected in two Sacramento County backyard flocks, health officials say
Highly pathogenic avian influenza was confirmed in two different backyard poultry flocks earlier this month, Sacramento County health officials said.
Finally, a Chance to Stem the Torrent of Corporate Money in Politics
Montana is in the forefront of a movement to use state powers to fix the problem unleashed by the Supreme Court.
Phoenix food vendor gets unexpected business boost after bank employees rescue him from storm
FOX 10 Phoenix reports on the heartwarming moment PNC Bank employees helped longtime food vendor Hilario Cruz Cruz and his cart escape powerful winds and hail. (Credit: FOX 10)
Can Michigan Conjure Up Some Halloween Magic at Rutgers?
Michigan offensive coordinator Jason Beck took a complete bashing from media and fans across college football’s national landscape this week […]
Proposed Health Insurance Rebate Reduction Fuels Debate
New changes that would reduce rebates for older patients with high healthcare costs are ‘not socially responsible,’ according to one clinician.
Patrick Stewart, renowned actor and ‘Star Trek’s’ Captain Picard, dies at 86
The distinguished British actor of stage and screen passed away Wednesday (Oct. 28) in Los Angeles.
AWS will be a $1T business, Jassy says. But first, it will spend big.
Amazon wants to be the king of AI cloud computing and become the first $1 trillion revenue business. But to do that it will have to continue on its capex spending spree, its CEO said Thursday.
AWS will be a $1T business, Jassy says. But first, it will spend big.
Amazon wants to be the king of AI cloud computing and become the first $1 trillion revenue business. But to do that it will have to continue on its capex spending spree, its CEO said Thursday.
Islanders vs. Wild game thread: Hello, Shabanov
The Islanders return to Minnesota, where their last trip was a dream pond hockey moment with their now-former captain. No more 11/7 hi-jinks tonight, they’ll dress the standard 12 forwards and 6 D. Matt Kessell draws the short straw. The Wild have been on the road for 10 of their first 14 but they’re doing […]
Glen Carbon business has been capturing time for 20 years
By Kathy Turner • Time. Sometimes it seems to pass quickly. Sometimes it seems to drag. If we think back to how quickly our children grew up, it can often seem fleeting. But if we’re waiting for our garden vegetables to reach maturity, it can be an eternity. There is a small business in Glen…
John Calipari's latest freshman haul leads No. 12 Arkansas vs. Pine Bluff
No.12 Arkansas' revolving door of "one-and-dones" is expected to spin again this season.The remade Razorbacks will bring the nation's No.1 recruiting class into their season opener against Arkansas-Pine Bluff on Tuesday in Fayetteville, Ark., the first meeting between the two programs.
North Dakota Health and Human Services Responds to 2025 Biennial Audit | Health and Human Services North Dakota
Bismarck, ND (October 29, 2026) - North Dakota Health and Human Services is pleased to say the 2025 biennial audit released by the State Auditor’s Office shows strong overall performance across its programs, safeguards and operations. In a biennial budget of nearly $6 billion, auditors identified only seven findings, which demonstrates effective oversight and responsible program management.
Humans accidentally canceled the next ice age — but it's no reason to celebrate, scientists say
A shrinking ice cap in Arctic Canada tells a striking story of how humans may have halted the planet's next ice age by burning fossil fuels, according to new research.
Hugh Jackman, William Shatner and George Takei among those paying tribute to Patrick Stewart
Patrick Stewart, the beloved actor known for his roles as Capt. Jean-Luc Picard in “Star Trek” and Professor Charles Xavier in “X-Men,” has died at 86
ESPN taps CBS Sports executive to lead news division
Adi Joseph is trading in a closet full of CBS Sports caps for the four most recognizable letters in sports media. Joseph announced on LinkedIn that he’s departing CBS Sports after nine years to become ESPN’s vice president of news, succeeding David Kraft atop the network’s newsgathering operation when he starts on Monday. The move…
Explore Sioux Falls through the lens of a local
"The best way to explore Sioux Falls like a local is to hear from the locals themselves." This video series helps capture those stories.
Oregon makes second try at own health insurance marketplace. How is this time different?
More than a decade after a botched rollout, the state is poised to launch its own system for a marketplace once again.
City of Seattle opens access to capital for Seattle small businesses
The Seattle Office of Economic Development, in partnership with Grow America and Mayor Katie Wilson, has revamped its Capital Access Program to provide affordable financing to Seattle small businesses at a new, lower fixed interest rate.
Legendary stage, screen and TV actor Patrick Stewart dies
He's probably best known as Professor Charles Xavier and Captain Jean-Luc Picard from the “X-Men” and “Star Trek: The Next Generation” series and films.
Patrick Stewart, ‘Star Trek’ and ‘X-Men’ actor, dies aged 86
(CNN) — Patrick Stewart, the legendary British actor best known for his role as Captain Jean-Luc Picard in the long-running “Star Trek” TV series, has died at the age of
Patrick Stewart, ‘Star Trek’ and ‘X-Men’ actor, dies aged 86
(CNN) — Patrick Stewart, the legendary British actor best known for his role as Captain Jean-Luc Picard in the long-running “Star Trek” TV series, has died at the age of
"Thriller on Themis" flash mob gathering in downtown Cape
VintageNOW Productions’ second “Thriller on Themis” brings a Michael Jackson-inspired performance and street dance to downtown Cape on October 30.
Starbucks is about to report earnings. Here's what to expect
Starbucks stock has climbed about 24% this year, raising its market cap to roughly $119 billion.
Why Miami Is a Destination for Latin America’s Political Exiles
The city’s Hispanic majority, news media reach and air links to Latin America have made it an ideal base for politicians escaping their home countries.
Modesto’s Timothy Olyphant about to return in hit streaming series and new film
He got a promotion to series regular in Apple TV show.
Platform Science Launches Four New Fleet Apps to Streamline Operations
These new capabilities enable fleets to identify operational problems earlier, scale safety coaching across large driver rosters, share delivery visibility with customers, and take direct control of in-cab video settings – all from the back office.
Monte Carlo Launches Bayes, an AI Teammate That Fixes Production AI Agents and Their Data
The agent trust platform delivers self-improving agents, so enterprises can scale trust at the speed of AI SAN FRANCISCO, Oct. 29, 2026 — Monte Carlo has launched Bayes, an AI teammate that brings its platform capabilities into a single system to autonomously detect, troubleshoot, and fix issues across agents and the data they run on. […]
Michigan State Basketball: End-of-Season Betting Odds
Tom Izzo faces immense pressure to end a championship drought as Wooden Award favorite Jeremy Fears leads a high-stakes roster through the grueling Big Ten betting landscape.
Decapitated man buried near fort in Roman-era Scotland gets a new virtual face
See the new facial reconstruction of a man from Roman-era Scotland who was decapitated after his death and buried near a Roman fort.
MLS announces 2027 Sprint Season schedule
Major League Soccer announced today Sporting Kansas City’s 14-game schedule for the 2027 MLS Sprint Season, which will launch the league’s transition into its new summer-to-spring calendar to align the MLS schedule with the world’s top soccer leagues. Sporting Kansas City will kick off the Sprint Season in Houston with
Orlando City announces 2027 MLS Sprint Season Schedule, presented by Orlando Health
The Lions’ 13th MLS season kicks off at home on Feb. 20 against New England Revolution
Commentary: Science shapes Michigan policy. Voters deserve to know candidates’ views.
Policy decisions do not happen in isolation, nor are they confined to Capitol Hill or Lansing. Decisions made across all levels of government directly affect Michiganders’ health and livelihoods. From monitoring our food supply to protecting drinking water, scientists help governments identify risks, evaluate possible responses, and decide what actions to take. Recent events in […]
Commentary: Science shapes Michigan policy. Voters deserve to know candidates’ views.
Policy decisions do not happen in isolation, nor are they confined to Capitol Hill or Lansing. Decisions made across all levels of government directly affect Michiganders’ health and livelihoods. From...
Well-paced, tightly wound ‘Witch’ smolders at American Players Theatre
The devil wears leather in Jen Silverman’s sinister fable, onstage through Nov. 22 at the classical company in Spring Green.
Science Lab: Dear Cowboys, blitz the QB.
Welcome to "The Science Lab", a place where football facts and in-depth analysis always triumph over feelings.
Humans accidentally canceled the next ice age — but it’s no reason to celebrate, scientists say
A shrinking ice cap in Arctic Canada tells a striking story of how burning fossil fuels may have stopped an ice age in its infancy, new research finds
Fur merchant revives retail business, battles activists
Nearly two decades after shutting down his shop in Portland, Ore., fur merchant Gregg Schumacher is stepping back into the retail business. The new iteration of Schumacher Furs has returned […]
PODCAST: Keeping Native capital flowing through political change
Native CDFIs finance homes, support small businesses and create jobs. Keeping capital flowing into their communities also requires a voice in the policy decisions that shape federal funding and bank investment. In a new episode of Difference Makers 3.0, Native CDFI Network CEO Pete Upton and policy consultant Ian Record join host Brian Edwards to […]
PODCAST: Keeping Native capital flowing through political change
Native CDFIs finance homes, support small businesses and create jobs. Keeping capital flowing into their communities also requires a voice in the policy decisions that shape federal funding and bank investment. In a new episode of Difference Makers 3.0, Native CDFI Network CEO Pete Upton and policy consultant Ian Record join host Brian Edwards to […]
Arkansas Tech Wins 2026 Bowling for Business Title
Arkansas Tech University captured first place in the 2026 Bowling for Business event hosted by the Russellville Area Chamber of Commerce at Strikers Bowling Alley on Friday, Oct. 23. The ATU team consisted of Dr. Russell Jones, ATU president; Dr. Jeffrey Cass, dean of the ATU College of Arts and…
Business builder Joe Haddad to headline Ashland University ethics lecture
Joe Haddad, a business leader whose career blends entrepreneurship, leadership development and faith-based service, will discuss the role of Christian ethics in building thriving organizations during Ashland University's Gordon E. Heffern Lecture on Christian Ethics in Business on Nov. 16.
Mark Walter Reveals Spending Plans for Dodgers’ Future
Will a potential salary cap slow down the Dodgers? Owner Mark Walter reveals his future spending plans and why the team will remain elite.
Campaign cash floodgates open after state regulators lift dollar caps
At least $350,000 has been given in two big lumps, including one that went into a heated state Supreme Court race — shortly after a spending cap got lifted.
Captive owners find new ways to finance risks, manage losses
Captive insurance companies are increasingly used for more than traditional risk financing, as owners seek to improve loss prevention, manage capital more efficiently and extend insurance services to…
Jane Schoenbrun: ‘Entertainment is a filtered version of our traumas’
We speak to the acclaimed director of Teenage Sex and Death at Camp Miasma about trans ‘representation’, the trap of capitalism, and their debut novel, Public Access Afterworld
Risky business: Petrochemicals industry faces overcapacity, disappointing growth
The global petrochemicals industry has entered an extended period of financial underperformance driven by too much supply and not enough demand.
High-level Roundtable: Safeguarding Sexual and Reproductive Health and Rights during Global Health Architecture Reform
How can sexual and reproductive health and rights (SRHR) be safeguarded during global health architecture reform? At a high-level roundtable hosted by the Government of Spain and the Government of South Africa, in its capacity as Chair of the Global Leaders Network (GLN), with support from PMNCH and WHEN, participants called for sustainable domestic financing, rights-based health systems and meaningful civil society engagement.
Booker: Moment is here for KY to put common sense over corruption, people over politics
Charles Booker makes his case to voters before Election Day.
Advancing SAP Lakehouse and New Data Fabric Innovations in SAP Business Data Cloud for the Autonomous Enterprise
Explore the new lakehouse and business data fabric capabilities that will help enterprises build AI agents act with greater autonomy.
In Creole Country, Black Residents Ask What the Fight for Voting Rights Delivers
Opelousas has shaped the fight for Black voting rights for centuries. Today, residents disagree over whether Democrats, Republicans, or racial solidarity offer a path forward.
CMS COO: Hospice, Home Health Moratoria a Successful Approach
The U.S. Centers for Medicare & Medicaid Services’ (CMS) temporary moratoria on hospice and home health provider enrollment in Medicare has been
Wisconsin price checks cited in federal lawsuit against Dollar General
No store in the Madison area is specifically mentioned in the lawsuit, which accuses the retail giant of systemic pricing inaccuracies and overcharges.
How hospitals are reworking care for sicker patients
Hospitals are treating sicker patients, spurring health systems to expand capacity, standardize care and cut costs.
A golden age of science is coming
It’s almost hard to remember, but just a few years ago, a lot of very smart people thought that science was in terminal decline. Respected researchers were writing papers with titles like “Are Ideas Getting Harder to Find?”, “Papers and patents are becoming less disruptive over time”, and “Slowed canonical progress in large fields of science”. In 1996, science writer John Horgan even published a book called The End Of Science: Facing The Limits Of Knowledge In The Twilight Of The Scientific Age. The fundamental idea was that the Universe only has so many insights to discover, and that we’ve picked the low-hanging fruit. It was the idea that Joseph-Louis Lagrange expressed when he said that “we cannot find more than once a system of the world to establish.” As the big ideas and the simple ideas get mined out, we’re forced to throw ever more brains at the mysteries of nature just to keep scientific progress going at a fraction of its old pace: It looked like science was hitting a wall. Then along came AI. It’s far too early to tell how much AI will eventually speed up the growth of total factor productivity. But already we can see signs of a speedup in science. Anthropic Founder Jack Clark assembled some of the hopeful data points in a recent lecture: [ Dror Poleg@drorpoleg "If you pick different parts of science, you see the same pattern show up: Progress is accelerating, and it has started to accelerate in the last two years." Jack Clark @jackclarkSF I’m speaking at the IMF in an hour about the singularity and why I believe it has begun and the choices we'll need to make. Watch live here: https://t.co/Hj9HzcXx5h 6:08 PM · Oct 18, 2026 · 21.2K Views 2 Replies · 10 Reposts · 123 Likes ](https://x.com/drorpoleg/status/2111882070376980529) Anthropic is accelerating its investment into drug discovery, and is already announcing some impressive preliminary results: [ BioTender@Junioryu136689 BREAKING: Anthropic unveils early results from six Claude-powered drug development collaborations. • 70% shorter CAR-T signaling domain • ~35,000 antibody designs • >10× tighter antibody binding • 89% less batch-record review time Still largely preclinical. Anthropic @AnthropicAI Over the past few months, Anthropic scientists have engaged in deep research partnerships with six organizations developing new medicines. We've also begun drug discovery efforts of our own. In doing so, we’ve learned much more about how Claude can support the many stages of 9:43 PM · Oct 27, 2026 · 11.2K Views 3 Replies · 24 Reposts · 205 Likes ](https://x.com/Junioryu136689/status/2115197821150495150) Claude also appears to be enabling rapid progress toward a treatment for food allergies. OpenAI, meanwhile, announced a possible breakthrough treatment for neurodegenerative disease. Meanwhile, Google Cloud Chief Scientist Pushmeet Kohli has a list of recent scientific advances that have been enabled by its new Gemini model, including breakthroughs in nuclear fusion reactor design, rare disease research, and quantum computing: [ Pushmeet Kohli@pushmeet Gemini 4 Argon is a step change in model performance. In recent weeks, it has had a transformative impact on the Science projects in our team at @GoogleDeepMind and our external collaborators, and helped make a number of remarkable advances across scientific disciplines. 🧵👇 4:47 PM · Oct 13, 2026 · 36.5K Views 8 Replies · 41 Reposts · 497 Likes ](https://x.com/pushmeet/status/2110049807385702623) But as cool as these stories sound, they’re just very minor, preliminary efforts. There are a number of reasons to think that AI is going to propel us into a golden age of scientific discovery. That age might not last forever — AI might still run into diminishing returns eventually. But the next few decades are probably going to be an absolutely amazing time for human science. The number of “effective researchers” is no longer limited The most important input into science is scientists themselves. Until this year, that meant human brains — talented, highly trained human brains. The number of trained human brains could be increased by sending more people to grad school, but only to a point — the smartest people tend to be sent into the hardest research fields first, and if you 10x the number of researchers, the average quality will go down. This constraint was already starting to bite, as Ekerdt and Wu argued in 2024: We argue that a substantial portion of the downward historical trend in U.S. research productivity is a composition effect resulting from self-selection in researcher ability and the dramatic expansion of the research sector…[W]e find that this composition effect has lowered average researcher ability by between 37% and 53%[.] And of course, low fertility was making the problem worse, because fewer children meant fewer people who were able to become future scientists. AI just blows up this constraint completely. If an AI agent can function as an autonomous researcher, there’s no constraint on the number of researchers in the world — you can just build more of them, by building more computer chips and data centers that enable the running of more AI agents. Whether or not massive hordes of agents can collaborate to solve individual problems much faster, increasing the number of agents allows them to tackle many different research questions in parallel. What’s more, these AI “researchers” can be trained incredibly quickly compared to human beings. A human scientist takes decades to train, and more years to reach the frontier of their research field by diligent reading and conversation. This is the “burden of knowledge”, and it’s commonly believed to be one reason ideas have been getting harder to find — by the time human scientists can get up to speed, they’re often so old that their ideas are no longer novel. AI just annihilates this constraint — it can assimilate the entire literature and reach the frontier of research extremely quickly, and it can also tell human scientists where the frontier lies without forcing them to discover that for themselves. It can also pivot to new research directions more easily than humans can. And there’s also a self-reinforcing economic cycle here. Because scientific advances enable higher GDP, they enable more resources to be invested into the creation of yet more electronic “scientists”. Now that doesn’t mean the amount of scientific research goes to infinity — there may still be some essential bottleneck task that human researchers are still needed to perform. There are some indications that AI’s progress on open-ended conceptual research tasks is slower than in other dimensions, and it may be that humans are still needed to provide some of this long-term conceptual thinking. I’d bet against this being true for much longer, but it might be true for a long time. Even in this most “pessimistic” case, though, the amount of effective capital that scientists can use to leverage their work just went up by a lot. AI eliminates the theory bottleneck Science proceeds by an iterative process of theory and experiment. The theory part of that cycle is typically short, but non-trivial — it took a couple of years after the blackbody radiation spectrum was observed for Max Planck to come up with the quantum hypothesis to explain it, and decades longer before quantum theory as we now know it was created. It took about a year for Watson and Crick to figure out the shape of DNA after the requisite data was gathered. AI will basically eliminate the theory bottleneck entirely — or at least shorten the turnaround time between experiment and theory by an order of magnitude. AI is an absolute beast at math. Recently, an OpenAI model solved some of the most important open problems in computer science, math, and theoretical physics, and no one even batted an eyebrow because that sort of triumph is becoming increasingly commonplace. One of those solutions was a proof that the Standard Model of Particle Physics could be mathematically well-defined — a problem that human theorists had so far been unable to tackle. Not all research relies equally on theory, but understanding novel experimental results almost always involves some important component of either mathematical or spatial reasoning. That part of the task has now been made much, much faster. And on top of that, science is now open to a greater number of humans who aren’t naturally good at theorizing. AI can read the whole literature Much of the work of human scientists involves reading and understanding endless amounts of papers and going to endless conferences and seminars. The purpose of that work is to understand the existing scientific literature. Understanding the literature allows scientists to do the following things: Come up with new ideas for hypotheses to test Avoid doing research that someone else has already done Synthesize approaches from different areas or fields AI can reduce this effort to almost zero. Consider this excerpt from OpenAI’s blog post about their new research into neurodegenerative disease: The team divided the analysis among thousands of AI agents powered by GPT‑Rosalind, an approach we call distributed biological reasoning. The agents examined a whole-brain CRISPR atlas…a dataset showing how gene disruptions affect different types of cells across the mouse brain. Each agent investigated a gene disruption, analyzed cellular responses, searched scientific literature, and proposed explanations for the results. Their reports were combined into a reasoning atlas linking genes, cellular effects, relevant publications, and possible biological mechanisms. The research team estimated that comparable human analysis and literature review, conducted one perturbation at a time, would take months to a year. The agents reproduced findings from human analyses while uncovering additional leads. Their assessments of novelty and scientific value also aligned with judgments from blinded human experts. These findings help prioritize further experiments needed to test the proposed biological mechanisms. Some of these insights point to new leads for understanding brain disease. [emphasis mine] This is one case in which parallel work by a large number of agents really does make a huge difference: [ Haider.@haider1 this is actually insane openai deployed thousands of GPT-Rosalind agents to analyze millions of mouse brain cells in 32 minutes, work that could take human researchers months to a year also the agents uncovered new leads for brain diseases like Alzheimer's and Parkinson's OpenAI @OpenAI GPT-Rosalind surfaced a new lead for drug discovery: could restoring cholesterol transport protect neurons from degeneration? DCTN1 is a gene linked to Perry syndrome, a rare neurodegenerative disorder. In mouse-brain data, disrupting it increased expression of genes involved in 2:41 PM · Oct 21, 2026 · 51.5K Views 26 Replies · 95 Reposts · 1.26K Likes ](https://x.com/haider1/status/2112917197903540516) Not only does instantaneous literature review vastly speed up the research process, but it allows AI to make novel conceptual leaps from combining approaches from wildly different fields of research. AI regularly does this in math research, combining results, approaches, and theorems from far-flung places that no human mathematician would have thought to combine. It can do it in science, too. Much of scientific innovation, historically, has been “recombinant” innovation — scientists applying insights from one field to another. With AI, essentially all research is now cross-disciplinary — AI can read not just the literature on a particular subject, but the literature on a million other subjects that might have produced useful techniques or insights for the problem at hand. Superscience So far, all of the factors I’ve listed are ways that AI can speed up science as it’s already done. I’ve basically described how AI can send gigantic hordes of superhumanly fast, superhumanly well-read, superhumanly mathematically gifted researchers to re-accelerate scientific discovery. But it’s also possible that AI will enable types of discovery — and ways of understanding the natural world — that no network of humans, no matter how large or how brilliant it was or how long it had to work, would ever be able to discover. In a post back in July, I wrote about how that might work: What if there are lots of…aspects of the Universe that [are] too complex to understand in terms of simple laws, but not so complex that they just dissolve into unknowable chaos? It’s possible that we can reliably control these complex phenomena with AI, even if we never reduce them to the kind of principles that we can teach a grad student in a textbook… Another way of saying this is that there may be laws of the universe that humans can’t understand but AI can. I call these “cloud laws” — causal regularities that can be exploited by technology, but which are too diffuse and complex for an individual human being to either intuit or communicate… Perhaps social sciences like economics, sociology, and political science obey similarly complex regularities, and AI can help us find them. Perhaps there are physical processes — plasma, or topological materials, or aerial turbulence, etc. — that obey cloud laws instead of chaos?… [H]uman collaboration is bottlenecked — it’s limited by our ability to intuit patterns at an individual level, and to communicate these patterns from one individual to another. AI, being a computer, just doesn’t have this sort of limitation; it can work with vast, diffuse patterns without having to break them into pieces or simplify them in order to compress them into the tiny pipelines of person-to-person explanation… If much of the Universe turns out to be ruled by cloud laws, we could be on the precipice of a scientific renaissance. In order to discover cloud laws, AI will need huge amounts of data about the natural world. AI figured out human speech by assimilating essentially all of the text humans have ever written. If it’s going to figure out hidden patterns in biology, neuroscience, materials science, etc., it’s going to need similarly massive amounts of data from physical instruments. That data will be far, far more than humans — individually or collectively — would be able to parse, label, characterize, or model. But AI was built to do this. If scientists simply build huge arrays of sensors to measure complex phenomena like the brain, the cell, the economy, etc., they may be able to feed this flood of data to AI directly and bypass human cognitive intermediation entirely. AI would then learn about the world directly, and it might learn things that humans never could. This “superscience”, if you want to call it that, would actually go beyond the kind of science humans have done heretofore. Many of the technologies it yielded would be beyond human comprehension — indistinguishable from magic. But to the AIs, they would make perfect scientific sense. In any case, it seems clear that the scientific slowdown that threatened human progress will now be delayed — at least for a while. Unless humans have somehow found most of the actual exploitable regularities in our Universe, we’re about to enter a new golden age of science. Subscribe Share
Like 'The Matrix,' but real: Google's Genie 4 brings science fiction to life
Google DeepMind unveils AI capable of generating photorealistic, interactive 3D worlds with sound, dialogue and realistic physics, as Israeli rival Decart draws attention amid reports of a potential $7 billion Amazon acquisition
Last Second Goal From Montour Secures Kraken Win Over Toronto
After squandering a three-goal lead, Seattle reclaimed momentum when Brandon Montour’s late-game rocket stunned Toronto, clinching a thrilling victory to cap off the Kraken's four-game home stand.
NC House race breaks national spending records + Asian voter turnout rises in NC
Read Under the Dome for the latest politics news daily.
Rock Hill isn’t the same city Trump visited a decade ago. Just look at the venue
A change in location is more than logistics. It shows the resilience of a community that is redefining its downtown corridor, again.
Is AI more a partner, competitor, or crutch for biomedical scientists?
Biologist Paul Knoepfler asks: Could overdependence on AI make us less capable as researchers?
Global Health & WASH
The US National Institutes of Health reopened its center and program-project machinery in force. NIGMS is funding Collaborative Program Grants for interdisciplinary teams, NIAID opened both its Immune Tolerance Network and a next-generation R&D call, the NCI runs its Carcinogen Hazard Assessment Monographs program, the National Library of Medicine is funding institutional training in biomedical AI and data science, and NIH reopened its Centers for AIDS Research. The tell: these pay for standing centers and multi-year consortia at institutions with an existing funded research base, not one-off projects, so the fit is an established US research institution, not a single investigator. Disease-specific foundations are again funding the researcher, not just the research. The Parkinson’s Foundation opened its Paul Oreffice Innovations in Care Award and the National Ataxia Foundation its Research Seed Money Grant. The tell, the same one we flagged last cycle, is a named early-career or seed award that builds a pipeline of scientists committed to one condition, so what wins is a researcher willing to specialize. The post-USAID global-health money is routing through a State Department program statement and multilateral innovation funds. The US Department of State’s Bureau of Global Health Security and Diplomacy opened its Advancing Global Health Annual Program Statement, Grand Challenges Canada opened Nexa Lighthouse for climate and health innovation in Asia and the Pacific at USD $250,000 to $2,000,000, and CEPI opened a rolling call on vaccine-manufacturing analytics. The tell: the largest health money this cycle sits in a standing program statement and in staged innovation vehicles, not in a single bilateral grant. Total Estimated Funding Pool: ~$35.4M across discrete grants. (Separately, large national-formula envelopes not counted in this total: U.S. Department of State, Bureau of Global Health Security and Diplomacy (GHSD).) This post is for paid subscribers. This helps support the time and effort it takes to curate and organize these opportunities. Subscribe To keep this accessible to everyone who needs it, we’re happy to offer pay what you can rates. You can find more details here. New opportunities: Paul Oreffice Innovations in Care Award, Parkinson’s Foundation. *New!* *Closing soon!* The Parkinson’s Foundation created the Paul Oreffice Innovations in Care Award to fund clinicians rethinking how people with Parkinson’s disease receive care. The Foundation is using pilot funding to move promising ideas into testable projects, backing work across four lanes: strengthening community clinician capability, redesigning care models, building patient-centered technologies, and defining the minimum clinical datasets that make better standards possible. It wants hypothesis-driven, clinically grounded projects that can generate evidence strong enough to attract further funding. By opening the door to clinicians at every career stage and strongly preferring projects that involve people with Parkinson’s in their design, the Foundation signals that it values practical, patient-shaped innovation over prestige. The strongest fits are US-licensed clinicians with a focus on Parkinson’s and an institutional home for applied care research. Geographies: united states. Who can apply: Clinicians of all career stages, from fellows to established faculty, who are licensed to care for patients in the United States and have a significant focus on Parkinson’s disease. Physicians must have completed a neurology residency (or justify how their training pathway benefits people with PD); allied health professionals must hold an advanced degree, typically a PhD. Fellows, those in mentored positions, and those within two years of starting an independent position require a mentor and a mentor support letter. The sponsoring institution’s grants office is the authorized recipient and funds are disbursed to the institution. Funding amount: Maximum of $200,000 over two years; up to three awards. Targeted Sectors / SDGs: Health; Innovation; Science & Technology. Deadline: November 1, 2026. Learn more and apply here. Design and Deliver the Next EIT Health Bootcamps, EIT Health. *New!* *Closing soon!* EIT Health is opening its call for consortia to design and deliver the next generation of its health start-up bootcamps, funding the curriculum, masterclasses, mentoring, and investor engagement that turn early health ventures into fundable companies. The organization is using these learning paths to strengthen Europe’s health innovation pipeline across digital health evidence, deep tech and AI commercialization, cross-border investment, and patient access. What EIT Health wants to back is not a single course but durable delivery capacity built by partners who span industry, education, and research. Requiring multi-country consortia and a revenue-sharing stake in the programs signals that EIT Health expects these bootcamps to outlast the grant. The strongest fits are established training providers, universities, and industry partners with proven reach into health entrepreneurs. Geographies: Europe. Who can apply: Consortia only (individuals cannot apply), comprising a minimum of two and a maximum of five independent legal entities. Partners must cover at least two sides of the Knowledge Triangle (industry, education, research), including at least one industry organisation, and at least two entities must be legally established in different Horizon Europe countries. Funding amount: Foundational Learning Path: up to EUR €112,000; Thematic Learning Paths: up to EUR €124,500 per path (up to four thematic projects); up to EUR €610,000 total EIT Health funding available under the call. Targeted Sectors / SDGs: Health; Innovation; Science & Technology; Economic Development & Livelihoods. Deadline: November 2, 2026. Learn more and apply here. Technology Transfer Offices & Entrepreneurship Support Call (Beyond the Lab: From Research to Venture), EIT Health. *New!* *Closing soon!* EIT Health is opening its Technology Transfer Offices and Entrepreneurship Support Call to fund consortia that will deliver the Beyond the Lab: From Research to Venture program for healthcare researchers. EIT Health is using the grant to build local capacity for turning laboratory science into incorporated start-ups, paying experienced technology transfer offices and entrepreneurship support providers to run masterclasses, structured mentoring, and a closing Pitch Day across two cohorts. It wants to back organizations that can walk researchers from discovery to company formation, not just teach theory. Requiring two transfer offices plus one venture-building provider signals that EIT Health values proven commercialization experience alongside academic reach. The strongest fits are European research-commercialization teams with a track record of moving health innovations toward investable ventures. Geographies: Europe. Who can apply: A consortium of two Technology Transfer Offices (representing higher education institutions or research organisations) and one Entrepreneurship Support Provider with demonstrated experience in venture building and start-up support. Applicants may apply for more than one learning path where they can demonstrate the required expertise and capacity for each. Funding amount: Up to EUR €77,000 in 2027 and up to EUR €77,000 in 2028 (up to EUR €154,000 total per consortium over two years). Targeted Sectors / SDGs: Health; Innovation; Science & Technology; Economic Development & Livelihoods. Deadline: November 2, 2026. Learn more and apply here. EIT Health RIS Country Representatives Call (2027-2028), EIT Health. *New!* *Closing soon!* EIT Health is seeking organizations to serve as Country Representatives across eleven Regional Innovation Scheme countries in central and eastern Europe for the 2027 to 2028 period. The money funds a national anchor in each country, an organization that maps the local health innovation ecosystem, connects startups and researchers to EIT Health programs, and builds the stakeholder relationships that let health ventures grow. EIT Health is backing local capacity rather than individual projects, which is why it accepts both single organizations and national consortia that span education, research, and industry. The requirement for co-financing signals that it wants representatives already embedded in their national systems. The strongest fits are established ecosystem builders with deep ties to health innovation stakeholders in one eligible country. Geographies: Croatia; Czech Republic; Estonia; Greece; Hungary; Latvia; Malta; Romania; Serbia; Slovenia; Turkey. Who can apply: Registered legal entities established in one of the eligible EIT RIS countries. Single organisations or national consortia may apply. Consortia must include at least two sides of the Knowledge Triangle (education, research and industry), and all consortium partners must be established in the same eligible country. Suitable applicants have demonstrated experience in healthcare innovation ecosystem development, innovation support and entrepreneurship, start-up acceleration, technology transfer, research and higher education, business support, and stakeholder engagement, with strong links to national innovation stakeholders. Funding amount: Up to EUR €182,000 per Country Representative (maximum funding per project); total call budget up to EUR €1,274,500; EIT Health funds up to 60% of total eligible project costs. Targeted Sectors / SDGs: Health; Innovation; Science & Technology; Economic Development & Livelihoods. Deadline: November 2, 2026. Learn more and apply here. Architects of Trust: Community-Driven Demand Creation for New TB Vaccines, Treatment Action Group (TAG). *New!* *Closing soon!* Treatment Action Group, with funding from Wellcome, is opening its Architects of Trust call to help communities prepare for the new tuberculosis vaccines now moving through late-stage trials. The money backs civil society and community-based organizations to raise awareness, surface local questions and concerns, and press policymakers toward equitable national rollout. By pairing each grantee with an advocacy mentor and running a strategy workshop alongside the Global TB Vaccine Forum, Treatment Action Group is building a durable advocacy bench rather than funding one-off outreach. The two-stage design, starting with a short expression of interest, signals that fit and community rootedness matter more than polished proposals. The strongest fits are locally trusted groups with real TB, immunization, or health advocacy experience and a committed project lead. Geographies: Brazil; Ethiopia; India; Indonesia; Kenya; Malawi; Mozambique; Nigeria; Peru; Philippines; South Africa; Tanzania; Vietnam; Zambia. Who can apply: National, subnational, or regional civil society organizations (CSOs) or community-based organizations based in one of the 14 eligible countries or in Eastern Europe/Central Asia regional networks, with experience in TB, immunization, or other health advocacy and in community engagement or policy advocacy; well integrated into stakeholder networks with membership or affiliation to other CSO or community networks; naming a dedicated project lead (’architect of trust’) who can attend the April 2027 Zaragoza forum in person; and holding (or committing to adopt) organizational policies on safeguarding (bullying, harassment, abuse, and harm), equity, diversity and inclusion, and legal compliance, research practice and governance. Funding amount: Grants of up to US$45,000 will be awarded to 8 CSO partners across 14 high-TB-burden countries plus regional networks in Eastern Europe and Central Asia; each grant funds 12 months of work. Targeted Sectors / SDGs: Health; Governance; Policy & Advocacy. Deadline: November 4, 2026. Learn more and apply here.
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Photo Essay: College of Science and Engineering Research Showcase
Fourth-year Mechanical Engineering major Jess Visaya and Fourth-year Mechanical Engineering major Dorette Pirie show off their soft robots. The robots are made to mimic worms, whose bodies bunch up before extending to propel themselves forward. The robots use pneumatic actuators to make linear movement outwards. Visaya and Pirie set up two of their worms with syringes attached to tubing which was then threaded through the end cap into the worms. Visitors to their station were encouraged to race the two worms by pumping the attached syringes. Third-year Biochemistry major Ira Evetts worked in Dr. Christopher Whidbey’s lab studying the vaginal microbiome, in an attempt to better understand the different microbes that build it up and how it affects health outcomes. Evetts’ research was specifically focused on lactobacillus iners, one of several bacteria naturally present in a healthy vaginal microbiome, and methylation systems. Fourth-year Mechanical Engineering major John Diesko Boehm and Fourth-Year Mechanical Engineering major Ian Agopsowicz hold up their “DAQMobile.” They built their project, a modified RC kit car, to help teach mechanical engineers about circuits and electrical design through real-world application. Fourth-year Mechanical Engineering major Ben Murphy holds up his mole crab and crawfish-inspired burrower. Murphy wanted to imitate the motion of a crab’s legs through robotics, with the primary goal to “turn the rotation of one motor into four alternating legs that would successfully displace soil.” Murphy was inspired by works that take inspiration from the natural world, and he found mole crabs particularly interesting. Although a mole crab is at an advantage with its burrowing being underwater, thus the sand being fluidized and easier to displace, Murphy’s machine is able to successfully burrow three centimeters into the ground. Second-year Mechanical Engineering major and Physics major Arabelle Miller shows off her rubber gripper, inspired by kirigami and origami. She took a piece of rubber and strategically cut slits into it to make it fold the way she needed, then glued googly eyes to the front. The gripper is able to hold up to 38 times its weight, or 226 grams. Third-year Mechanical Engineering major Joonseong Park talked about how his project took an unused and broken 3-D printer and transformed it into a testing platform for soft robotic grippers. The former-printer was reprogrammed and had its extruder part modified to be a mount for the grippers. Park shows off some of the other grippers that can be attached to the testing platform. Park classified grippers into two large categories. The first set of grippers is designed to deal with small delicate objects with great precision, and the second is made to lift heavy or large objects. Third-year Mechanical Engineering major Jiashuo Liu set out with a goal to deploy free open-source AI models to pre-existing robots to integrate object recognition and retrieval and command. The models are used to process the data received from the robots’ cameras in order to detect certain objects and their locations. Fourth-year Mechanical Engineering major Cole Purohit focused on agricultural automation of raspberry picking. His project utilizes kirigami to make grippers to close around a raspberry when the two ends are pulled. “Nobody wants to eat a squished raspberry,” Purohit said. Fourth-Year Biochemistry major Mariel Nolan’s project focused on bacteria and proteins within the bacteria whose functions are unknown. Nolan’s research is finding a way to isolate those proteins with the ultimate goal of determining their functions. Fourth-year Mechanical Engineering major Kai Boydon and Fourth-year Mechanical Engineering major Evan Nguyen show off their project, which uses custom extensors to help with the rehabilitation of stroke patients. They compared their project to a “party-popper” in the way it unfurls itself when placed under a patient’s fingers, helping the stroke patient rehabilitate finger movement. Boydon shows off the testing rig built for their project. It works as a mount for their extensor, as a way to test against resistance. Their program inflates the extensor through an air pump, which then makes the extensor push against the bed whilst an arduino calculates the force created and air pressure associated with the force. Navigate Left Navigate Right
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