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Seattle-area sunflower farms and more activities to send off summer

It can be hard to say goodbye to summer, but there are still a few more fun things to do in the Seattle area before fall begins.

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Sep 12 • 9:00 AM EDT • Entertainment • yakimaherald.com
‘Hunger Games’ prequel, ‘Digger’ and other big movies of fall 2026

This year's fall movie season offers up Godzilla, Jane Austen, Tom Cruise, a husband made of wicker and more.

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Sep 12 • 9:00 AM EDT • Entertainment • yakimaherald.com
Georgia vs. Western Kentucky time, TV channel, score, live updates

Georgia plays Western Kentucky in a week 2 game. Follow live score updates, highlights, injury news, key plays and instant analysis.

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Sep 12 • 6:01 AM EDT • Sports • sports.yahoo.com
Brenda Lucas: Community news for Saturday, Sept.12

Click for community news in the Huntington, West Virginia, and Tri-State area.

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Sep 12 • 4:45 AM EDT • Entertainment • herald-dispatch.com
For Liam Neeson, Zachary Levi, making ‘The Fix’ ‘a heck of an adventure’

“The Fix” revels in its action, patriotism and suspense as military veterans – led by Liam Neeson’s Larry and Zachary Levi’s Tucker – go undercover in the Mideast for a rescue and a big haul.

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Sep 12 • 3:51 AM EDT • Entertainment • bostonherald.com
Family therapist reveals how couples can keep politics from wrecking relationships

Dr. Anna Elton discusses why partisan disagreements can create tension between partners, and offers strategies for setting boundaries, staying curious and reconnecting after heated conversations.

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Sep 11 • 9:57 PM EDT • Politics • foxnews.com
Scientist Jay Hoying explores frontiers of tissue therapeutics

Jay Hoying can’t remember a time he didn’t want to be a scientist. He started out watching “Nova” on PBS when he was about 8 years old. He pursued his

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Sep 11 • 8:30 PM EDT • Science • unionleader.com
Maya Cinemas closes after 20 years of business

“It’s disappointing to see another longtime business leave our downtown, and it raises some questions about what’s happening in the area.”

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Sep 11 • 7:40 PM EDT • Business • montereyherald.com
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‘Call My Agent! The Movie’ review: Film channels series in the best ways

There’s not much to distinguish the movie, now streaming on Netflix, from an episode of the show, but that's a good thing, writes Moira Macdonald.

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Sep 11 • 5:00 PM EDT • Entertainment • yakimaherald.com
Williamson Health board dedicates room to Anderson

The Williamson Health Board of Trustees honored retiring Williamson County Mayor Rogers Anderson during his final board meeting Aug. 27, dedicating its board room in his name and unanimously granting

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Sep 11 • 4:12 PM EDT • Health • williamsonherald.com
Must-see fall Seattle theater shows: ‘Oh, Mary!,’ ‘Ragtime’ and more

Don’t miss “Oh, Mary!,” Taylor Mac, “Ragtime” and many more on Seattle stages this fall.

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Sep 11 • 4:00 PM EDT • Entertainment • yakimaherald.com
Life Sciences Companies Present Live at the September 17 Virtual Investor Forum

Live Presentations and Q&A Across Oncology, Fibrosis, Drug Delivery, Antibiotics, Cannabinoid Therapeutics, and Respiratory Imaging A Global Lineup Presents Live Online: 30-Minute Sessions, Audience Q&A, Replays On Demand NEW YORK, NY - Sept...

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Sep 11 • 3:05 PM EDT • Science • finance.yahoo.com
The biggest fall concerts coming to the Seattle area

From classic rock legends to new-school hitmakers, these are the biggest fall concerts coming to the Seattle area through Thanksgiving weekend.

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Sep 11 • 1:00 PM EDT • Entertainment • yakimaherald.com
Business Briefs for Sept. 12, 2026

This week's digest of area business announcements, milestones and news.

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Sep 11 • 12:59 PM EDT • Business • rutlandherald.com
Routine Reset: How to Prioritize Your Mental Health This Fall

School is back in session and life is getting back to normal, so psychotherapist Niro Feliciano stops by TODAY to share tips for resetting your routine. See her advice for dealing with shorter daylight hours and packed schedules, which includes “progress over perfection,” limiting phone use, going for walks, and more.

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Sep 11 • 12:46 PM EDT • Health • today.com
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Cosmos Health Secures Additional 2.5 Million Units Under New Five-Year Contract Manufacturing Agreement with Viofar; Total Orderbook Surpasses 27.5 Million Units

* 500,000 contracted units of ROSARTIA annually / 2.5 million over five years through a new long-term agreement at wholly owned subsidiary Cana Laboratories * Expands Cosmos Health's manufacturing presence in cardiovascular pharmaceuticals, adding production of statin-based lipid-lowering therapies to Cana's growing contract manufacturing portfolio * Cumulative contract manufacturing orderbook increases to more than 27.

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Sep 11 • 11:10 AM EDT • Health • finance.yahoo.com
Hormone therapy for menopause might have heart health benefits

Hormone therapy may do more than ease hot flashes and night sweats. A new study suggests it may also be linked to a lower risk of heart problems.

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Sep 11 • 10:15 AM EDT • Health • wxyz.com
Miami-area hospital to get new kids’ cancer center. How Palace founders are involved

The new center, made possible by a $15 million donation from Palace founders Helen and Jacob Shaham, will serve as a one-stop shop for care.

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Sep 11 • 5:00 AM EDT • Health • miamiherald.com
World Health Organization OKs Multi-dose Maternal RSV Vaccine

The new multi-dose RSV vial is expected to lower costs and simplify global distribution to protect infants from severe respiratory illness.

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Sep 10 • 8:12 PM EDT • Health • respiratory-therapy.com
Texas Health Resources mental health program integrates faith with therapy care

The program began in Alliance and expanded to Rockwall this year. It aims to go virtual in the coming months.

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Sep 10 • 7:54 PM EDT • Health • fortworthreport.org
David Petraeus: George W. Bush, Political Courage, and the Surge in Iraq

In the wake of the September 11 attacks, President George W. Bush launched what he called the War on Terror. It began with the invasion of Afghanistan in late 2001, which quickly toppled the Taliban and expelled al-Qaeda from its most crucial sanctuary. Then, in early 2003, American forces—with the support of foreign allies like the United Kingdom, Australia, and Poland—attacked Iraq, toppling Saddam Hussein’s regime and installing an occupation force in hopes of quickly transforming the country into a free and democratic state. Instead, the post-regime coalition authority made significant missteps, and a devastating insurgency erupted. And despite President Bush’s 2004 reelection, the war quickly lost popular support among the American public. In early 2007, Bush appointed General David Petraeus, who had already served in Iraq as a two- and three-star general, to lead allied forces in Iraq, which heralded a sea change in American strategy known as “the surge.” As part of our coverage looking back on 9/11 and the world it created, General Petraeus tells the inside story of one of the most consequential moments in the War on Terror. The general’s essay today is both a crucial history and a profile in political courage. It demands reflection as we take stock of the last 25 years. —The Editors By the end of 2006, the war in Iraq was failing. There is no useful purpose in softening that judgment with the passage of time. The bombing of the al-Askari mosque in Samarra by terrorists that February had accelerated sectarian violence and pulled Iraq into an increasingly vicious Sunni-Shia civil war. Al-Qaeda in Iraq and Sunni insurgent groups controlled substantial areas, Shi’ite militias operated with growing impunity in other parts of the country, and the Iraqi security forces were no longer capable of arresting the downward spiral. The strategy of transitioning security responsibilities to Iraqi forces, consolidating American troops on large bases, and progressively reducing the U.S. presence had clearly been invalidated by the escalating violence. The numbers conveyed the horror imperfectly but unmistakably. In December 2006, an average of 53 Iraqi civilians were killed by violence every 24 hours in Baghdad alone. Washington, meanwhile, was approaching its own breaking point. Public support for the war had fallen dramatically, President George W. Bush’s Republican Party had just lost control of both houses of Congress, and the bipartisan Iraq Study Group—of which future defense secretary Robert Gates was a member—had recommended a course that anticipated a substantially reduced American combat role. Many senior military leaders were deeply skeptical of sending substantial additional forces, advocating instead for an accelerated transition to Iraqi forces, the deployment of additional trainers and advisers, or other more modest measures with an eye to withdrawing U.S. forces. Virtually every political incentive pointed toward reducing America’s commitment. President Bush chose instead to increase it, a decision that remains, in my view, one of the most courageous presidential decisions of the 21st century.

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Sep 10 • 7:29 PM EDT • Politics • thefp.com
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Midwest City’s crisis team, joined by therapy dog Miles, takes proactive approach to mental health

Midwest City’s Crisis Intervention Response Team is trying to fix the root of mental health crises — with help from therapy dog Miles.

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Sep 10 • 6:25 PM EDT • Health • koco.com
Manitowoc, Sheboygan Week 4 high school football scores, live updates

A live look at Week 4 high school football scores from around the Manitowoc and Sheboygan areas.

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Sep 10 • 6:00 PM EDT • Sports • sports.yahoo.com
Susan Collins endorsed by National Federation of Independent Businesses at Naples event

P&K Sand and Gravel hosted the gathering.

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Sep 10 • 4:54 PM EDT • Business • pressherald.com
County Commission approves LOI for Ascension’s acquisition of Williamson Health

The Williamson County Board of Commissioners voted on Wednesday, Sept. 9, at a special called meeting, to approve a non-binding Letter of Intent (LOI) for the potential sale of Williamson

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Sep 10 • 4:33 PM EDT • Health • williamsonherald.com
Seattle’s Muz Fest celebrates Muslim culture and more

Muz Fest, a multicultural festival built around music, food, art and community, with a special focus on Muslim culture, takes place Sept. 12 at Victory Hall at The Boxyard.

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Sep 10 • 4:00 PM EDT • Entertainment • yakimaherald.com
11 things to do around the Seattle area this weekend

From late summer soft-serve to a multicultural celebration with a focus on Muslim culture, here are the latest local things to do around the Seattle area.

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Sep 10 • 4:00 PM EDT • Entertainment • yakimaherald.com
Sen. King asks education secretary for answers about mental health grant cuts

Maine's independent senator and a group of Democratic colleagues penned a letter to Linda McMahon asking that she distribute $1 billion in youth mental health funding.

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Sep 10 • 3:51 PM EDT • Health • pressherald.com
Africa’s top health body warns Congo’s Ebola outbreak is rapidly spreading beyond epicenter

The World Health Organization says the situation remains out of control.

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Sep 10 • 2:50 PM EDT • Health • bostonherald.com
Childhood Chemotherapy Leaves Lasting DNA Damage in Healthy Tissues

Certain chemotherapy drugs can age children’s healthy cells to levels comparable to those found in adult tissues.

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Sep 10 • 2:00 PM EDT • Health • insideprecisionmedicine.com
Platinum chemotherapy may cause decades' worth of DNA changes in children's healthy cells

The amount of DNA damage caused by certain chemotherapies used to effectively treat childhood cancer has been revealed, along with a hidden impact on the liver, paving the way for future research into ...

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Sep 10 • 2:00 PM EDT • Health • medicalxpress.com
Business tidbits: New partnership boosts Zullee Mediterranean Grill

A new financial partner could mean the expansion of Zullee Mediterranean Grill to new markets, but Yakima customers can still enjoy the same food and service they have come to

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Sep 10 • 2:00 PM EDT • Business • yakimaherald.com
Microsoft-owned Blizzard, video game union ratify contract

Employees across Microsoft-owned video game developer Blizzard have ratified a union contract with the company.

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Sep 10 • 1:00 PM EDT • Entertainment • yakimaherald.com
Little Mercury may be shrinking faster than scientists expected

The shrinkage represents a loss in diameter of as much as 14 miles.

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Sep 10 • 12:30 PM EDT • Science • bostonherald.com
Fall Fab Fest bigger than ever before

Western Michigan University students connected with their communities at the largest Fall Fab Fest to date in the WMU Student Center on Sept. 6, held by Lesbian, Bisexual, Gay and

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Sep 10 • 12:00 PM EDT • Entertainment • westernherald.com
Politics in the Therapy Session

Once upon a time, therapists took care to hide their ideological views from their patients, presenting instead a “blank screen” that allowed the therapeutic relationship to function as intended. Mark that down as one more casualty of the Age of Wokeness.

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Sep 10 • 11:08 AM EDT • Politics • donoharmmedicine.org
SPONSORED SEGMENT: Dees Integrative Health

Peripheral Neuropathy workshop

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Sep 10 • 10:45 AM EDT • Health • mysuncoast.com
New Seattle, WA arts leaders on biggest challenges, opportunities

Four newly appointed local leaders in the arts world speak with The Seattle Times about the state of the art scene today — the challenges as well as the opportunities.

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Sep 10 • 9:00 AM EDT • Entertainment • yakimaherald.com
Hormone Therapy For Menopause Might Have Heart Health Benefits

By Dennis Thompson HealthDay ReporterTHURSDAY, Sept. 10, 2026 (HealthDay News) — Hormone therapy started during menopause might reduce a woman’s risk of heart attack and stroke, a new study says. For common menopause symptoms such as hot flashes and night sweats, which affect as many as 80% of ...

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Sep 10 • 9:00 AM EDT • Health • usnews.com
The jail is a hospital: 90 percent of inmates need physical, mental healthcare

Alexandria Vega, a behavioral health specialist in the Deschutes County Jail, transitions from cell to cell. In one, an inmate is suicidal. In another she provides formal therapy. For a […]

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Sep 10 • 8:30 AM EDT • Health • bendbulletin.com
Global heat stuck on high. Scientists say August was Earth’s hottest month they’ve measured.

Global monthly ocean temperatures in August tied a March 2024 all-time record.

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Sep 10 • 7:55 AM EDT • Science • bostonherald.com
Exclusive: How politics in Miami and Cuba killed secret negotiations, U.S. energy deal

The agreement would have given the United States significant sway over Cuba as its main oil provider.

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Sep 10 • 5:30 AM EDT • Politics • miamiherald.com
Four Japanese scientists win prestigious U.S. Lasker Awards

One received the prize for his work on a sleep-regulating brain chemical, and a trio, for discovering an antibody therapy for hemophilia A patients.

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Sep 10 • 12:30 AM EDT • Science • japantimes.co.jp
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“What's your purpose?” New resource for Black mental health offers community healing

Bruh’s Healing Brothers is a new event series meant to connect Black male therapists with community members seeking mental health support.

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Sep 10 • 12:04 AM EDT • Health • signalcleveland.org
Tackling the Health Care Interoperability Problem | Targeted Oncology - Immunotherapy, Biomarkers, and Cancer Pathways
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Sep 9 • 6:11 PM EDT • Health • targetedonc.com
JLF Seattle, microcosm of Jaipur Literature Festival, comes to town

JLF Seattle, based on the Jaipur Literature Festival, offers a lineup of local and international award-winning authors.

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Sep 9 • 5:00 PM EDT • Entertainment • yakimaherald.com
Poetry Foundation honors Robert Pinsky with a $100,000 lifetime achievement prize

Former U.S. poet laureate Robert Pinsky has received a $100,000 lifetime achievement award. The Poetry Foundation announced the award on Wednesday. Pinsky, who served as U.S. laureate from 1997 to

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Sep 9 • 4:08 PM EDT • Entertainment • yakimaherald.com
These small Seattle theater spaces are making big moves

How new energy at Theatre Off Jackson, Annex Theatre and Seattle Open Arts Place is reinvigorating Seattle’s fringe theater scene, and why that matters.

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Sep 9 • 4:00 PM EDT • Entertainment • yakimaherald.com
MultiCare's statewide layoffs hit Yakima's North Star Lodge, business office

The leader of Tacoma-based MultiCare Health System told The News Tribune on Tuesday the not-for-profit network is cutting 138 positions.

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Sep 9 • 3:42 PM EDT • Business • yakimaherald.com
MultiCare's statewide layoffs hit Yakima's NorthStar Lodge, business office

The leader of Tacoma-based MultiCare Health System told The News Tribune on Tuesday the not-for-profit network is cutting 138 positions.

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Sep 9 • 3:42 PM EDT • Business • yakimaherald.com
Welcome back to the regular season in the Midcoast business scene

Events are up this Saturday, and look out for ways to get to know candidates.

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Sep 9 • 3:15 PM EDT • Business • pressherald.com
Business tidbits: Charlotte Russe to open in Valley Mall, new restaurant in Selah

A San Francisco-based retail chain specializing in clothing for women in their teens and 20s is opening next week at Valley Mall in Union Gap.

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Sep 9 • 2:00 PM EDT • Business • yakimaherald.com
New 'SNL' season will have Jalen Brunson and Inde Navarrette as hosts, music from Katseye, Rosalía

Newly crowned NBA champion Jalen Brunson of the New York Knicks will host “Saturday Night Live” when the new season begins later this month. Brunson, who helped the Knicks become

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Sep 9 • 1:17 PM EDT • Entertainment • yakimaherald.com
16 Seattle-area author events happening this fall

From national book tours to conversations with local authors, take note of these upcoming bibliophile events in the Seattle area.

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Sep 9 • 1:00 PM EDT • Entertainment • yakimaherald.com
Is it healthy for a child to play one sport all year? There’s a warning

Parents should take note of the medical concerns.

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Sep 9 • 12:38 PM EDT • Health • miamiherald.com
Yourgene Health Releases IVDR-Certified DPYD Assay for Chemotherapy Toxicity Detection

Yourgene Health launches IVDR-certified DPYD assay in Europe to detect 19 variants linked to fluoropyrimidine chemotherapy toxicity.

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Sep 9 • 11:21 AM EDT • Health • clpmag.com
Peripheral vascular disease: Answers to common questions

“Peripheral vascular disease is something we can often prevent or slow down by addressing the risk factors early,”

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Sep 9 • 10:32 AM EDT • Business • siouxfalls.business
Has Seattle become a bona fide EDM town?

As indie-centric summer festivals have faded in recent years, big-tent dance music events have flourished, fueling an EDM renaissance in a city that prides itself on its grungier legacy.

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Sep 9 • 9:00 AM EDT • Entertainment • yakimaherald.com
Two Whatcom County businesses opened last month; two others closed permanently

Check out Bellingham’s latest business news. We’re keeping track of openings and closings.

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Sep 9 • 8:35 AM EDT • Business • bellinghamherald.com
FiRa Consortium Appoints Sunil Jogi as President

BEAVERTON, Ore.--(BUSINESS WIRE)--Sep 9, 2026--

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Sep 9 • 8:03 AM EDT • Business • rutlandherald.com
HeRAMS Ukraine health services across oblasts August 2026 - All divisions [EN/UK]

Situation Report in English on Ukraine about Health; published on 9 Sep 2026 by WHO

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Sep 9 • 7:03 AM EDT • Health • reliefweb.int
HeRAMS Ukraine health services across oblasts August 2026 - legal entities [EN/UK]

Situation Report in English on Ukraine about Health; published on 9 Sep 2026 by WHO

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Sep 9 • 7:03 AM EDT • Health • reliefweb.int
Upstate Hospital opens clinic for youth who need walk-in mental health therapy

A prominent Central NY family donated $5 million to make the center a reality.

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Sep 9 • 6:00 AM EDT • Health • syracuse.com
Tarr family opens new Snap Fitness gym in Nitro, combines with physical therapy clinic

The Tarr family, owners of Generations Physical Therapy, opened a new Snap Fitness gym location at their Nitro, West Virginia, clinic in August 2026.

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Sep 9 • 6:00 AM EDT • Business • wvgazettemail.com
Brenda Lucas: Community news for Wednesday, Sept. 9

Click for community news in the Huntington, West Virginia, and Tri-State area.

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Sep 9 • 4:45 AM EDT • Entertainment • herald-dispatch.com
Southcoast Health adds seven new medical providers

Southcoast Health has expanded its medical team by adding seven new providers across several specialty areas.

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Sep 9 • 4:01 AM EDT • Health • heraldnews.com
‘Last Seen’ review: Apple TV mystery thriller gets lost down under

For a show that began as potentially darkly poetic or challenging, "Last Seen" (which premieres Wednesday on Apple TV) plays it far too safe, writes our reviewer.

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Sep 8 • 9:00 PM EDT • Entertainment • yakimaherald.com
UC Berkeley Welcomes QuantrolOx to its Quantum Innovation Corridor

Quantum researchers and campus leaders heralded the arrival of QuantrolOx at UC Berkeley’s Roger Herst Quantum Nexus. The occasion marks the first U.S. office for QuantrolOx, establishing a foothold

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Sep 8 • 8:31 PM EDT • Science • ls.berkeley.edu
Vallejo’s Empress Theatre amps up entertainment offerings, dining

“The idea is simple: there should be something happening often enough that people throughout Vallejo, Solano County, and the greater Bay Area can make the Empress part of their regular week,” says the Empress Threatre.

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Sep 8 • 6:52 PM EDT • Entertainment • timesheraldonline.com
September 10 Vallejo/Vacaville Arts-Entertainment Source: Activities

A National Day of Service and Remembrance is set for Saturday at 10 a.m. in Dixon.

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Sep 8 • 5:24 PM EDT • Entertainment • timesheraldonline.com
Scientists engineer ready-to-use cancer-fighting T cells for solid tumors

T-cell receptor, or TCR, therapy is a cancer treatment that genetically reprograms immune cells, called T cells, to hunt down cancer with precision. It's similar to another treatment, CAR T-cell therapy, ...

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Sep 8 • 5:00 PM EDT • Science • medicalxpress.com
North Carolina MCO Alliance Health Taps Cortica to Rein in Autism Spending, Improve Outcomes

Ready to dive into what's shaping autism therapy-payer relations? Be a part of the Autism Investor Summit East this November 9–10. Get your tickets here.

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Sep 8 • 4:03 PM EDT • Health • bhbusiness.com
Business Briefcase: Community Day 2026 has Mahanoy’s attention

MAHANOY CITY — Train rides? Check. Scores of vendors? Check. Delicious food? Check. And even pierogie-eating competition? Double check. A highlight of the annual Mahanoy City Community Day celebration set for Sept. 12 will be a serious e…

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Sep 8 • 1:00 PM EDT • Business • republicanherald.com
Best TV shows of fall 2026: ‘Slow Horses,’ ‘Monster,’ ‘VisionQuest,’ more

From a reimagining of a Stephen King classic to the return of a critically acclaimed crime drama, here are 16 shows to be excited about this fall.

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Sep 8 • 1:00 PM EDT • Entertainment • yakimaherald.com
Are Irving, LaVine, Holiday realistic for Heat? And surprising Richards info

The Heat’s challenges in landing one more impactful player. And some notable data on new backup center Nick Richards.

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Sep 8 • 11:01 AM EDT • Sports • miamiherald.com
The Row brings new retail, dining and entertainment to Heartwood

The Row, a new in-line retail center located in Poplar Place within Heartwood’s Town District, will bring a growing mix of dining, entertainment, services and specialty retail to one of the community’s most visible commercial areas at Exit 82.

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Sep 8 • 11:01 AM EDT • Entertainment • bryancountynews.com
AZ's R&D chief Barr touts internal 'science success story' after IL-33 antibody's stellar showing in COPD

With a detailed data drop that AstraZeneca’s R&D chief described as an internal “science success story,” the British Big Pharma has secured an FDA priority review for what it believes could become a flagship biologic in chronic obstructive pulmonary disease (COPD). In detailed results from the late-stage Oberon and Titania trials—first teased in March and detailed in full at the European Respiratory Society Congress in Barcelona this week—the drugmaker laid out the extent of its IL-33 inhibitor’s potential to reduce moderate and severe exacerbations in a wide range of COPD patients still struggling with those “lung attacks,” as AstraZeneca’s Sharon Barr, Ph.D., called them, despite using standard-care inhaled therapy. In the headline results, a 300 mg dose of tozorakimab given once every four weeks curbed those moderate and severe exacerbations in the studies’ primary population of former smokers by 29% in the Oberon study and 34% in Titania. In the overall population of both current and former smokers, these reductions were 30% and 29%, respectively, versus placebo and inhaled standard of care. The benefits also extended to clinically meaningful exacerbation reductions in all prespecified patient subgroups and specifically turned up promising signals in patients across a range of blood eosinophil counts, with Barr telling Fierce that “it’s the details that make this even more exciting than the high-level results that we’ve already shared.” In fact, during AZ’s tozorakimab poster presentation at the ERS 2026 Congress this past weekend, attendees were so enamored by the data that event organizers had to encourage people to clear the room and look at the other presentations on offer, Barr said in an interview. “I think it really speaks to the fact that there is a lot of buzz around these data because the entire respiratory community has been so desperate for new therapies for these patients,” she explained. The respiratory disease continues to represent a “staggering unmet medical need,” Barr said, highlighting the COPD exacerbations that the Oberon and Titania studies homed in on, which she added carry a greater mortality risk than a heart attack. “When a patient has a severe exacerbation, only about half of them are still alive within three and a half years,” she pointed out. As for tozorakimab specifically, Barr christened the molecule “an AstraZeneca science success story,” harkening several years back to the point at which researchers began to explore IL-33 as a driver of respiratory disease, and COPD in particular. At the same time, “there was still so much that wasn’t understood,” she admitted, highlighting the insight that IL-33 signals through both ST2 and EGFR through the RAGE pathway, a discovery Barr attributed to AstraZeneca's own scientists. Understanding the need to tackle both pathways in COPD—and aware of competitor candidates in the hopper, including one that bound ST2—the company ultimately had to make some “courageous decisions,” Barr said. These included taking a prior COPD molecule offline and going back to the drawing board to reinvent its potential IL-33 label “to make sure that we had a molecule that could block signaling through both arms of the pathway, through both the reduced form and the oxidized form, knowing that we wouldn’t be first, but striving to be best.” “When we put [tozorakimab] into the clinic, we firmly believed that we had a differentiated molecule, and we saw the other molecules blocking just ST2 or partially blocking IL-33, unable to deliver two positive pivotal studies in COPD,” Barr explained. “We kept marching forward because we believed our molecule was differentiated, and now I think we have the clinical validation that supports that.” Ultimately, AstraZeneca finds itself on much better footing these days when it comes to potential biologic rivals to tozorakimab in COPD. Sanofi and Regeneron’s Dupixent, for instance, is approved to treat COPD exacerbations in patients with high eosinophil counts, but not low ones. Meanwhile, the future has become cloudier for other next-gen IL-33 candidates from Sanofi and Regeneron, as well as Roche, which have suffered trial flops in recent years. One other potential ingredient for AstraZeneca’s success in its duo of studies was that the company was “ambitious in the trial design, willing to look at an all-comers population,” Barr said, “and willing to enroll the most severe patients.” Prior studies for would-be biologics rivals in COPD “avoided enrolling” those patients, she pointed out. She also highlighted the Big Pharma’s painstaking design of exacerbations in its trial, which “gave us a very rigorous readout,” and pointed to “the extra effort and investment” the company put in to understand the effect of mucus plugs in patients. Barr described mucus production as a “key feature in disease diversity,” noting that mucus plugs—obstructing clumps of mucus that block patients’ airways—are associated with worse outcomes in COPD. In its data announcement, AstraZeneca noted that an integrated analysis of Oberon and Titania found tozorakimab “demonstrated a reduction in patients’ mucus plug score,” with the pharma claiming its biologic is the first to deliver such results in a broad COPD population. “So being able to reduce those mucus plugs, we expect, is an important part of driving benefit for patients who are living with COPD,” Barr said. Again touching on the breadth of the study populations, Barr added that tozorakimab “worked across all eosinophil levels in both current and former smokers across all levels of lung function,” which she suggested “really simplifies decision-making for clinicians, and it allows them to offer therapy to the broadest possible patient population.” In the highest patient eosinophil count group, tozorakimab helped chart a 43% reduction in exacerbation risk, which Barr stressed were “unprecedented data.” In the mid-level group, AZ’s drug delivered a 23% reduction and, in the lowest group, a 34% reduction in eosinophils, which Barr said suggests efficacy “in all patient subgroups.” As for AZ’s recent guidance upgrade on the medicine’s sales opportunity, the lift from a $3 billion to $5 billion range to $5 billion plus was informed by multiple factors, Barr said, including the fact that “in 2024, there were multiple competitors, and there aren’t anymore.” Additionally, “we know that this is a massive unmet medical need, and this is a really incredible set of data that we think will be very convincing to the clinical community,” Barr said. Looking ahead to a potential evolution of the COPD treatment landscape, Barr noted that most patients start treatment in the community with an option like a triple therapy, and for them, having an option like AstraZeneca’s inhaler Breztri will remain a “really important part” of that journey. But of the patients uncontrolled on triple therapy, which Barr described as “about half of them today,” just a “small fraction” are currently eligible for biologic therapy, which she emphasized AstraZeneca is working to change. Understanding that COPD is not a “one-size-fits-all” disease, AstraZeneca is also looking at its antibody drug Tezspire for patients with T2-driven disease, and the company continues to think about new mechanisms for tackling COPD through both systemic and inhaled drugs, Barr said.

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Sep 8 • 10:50 AM EDT • Science • fiercebiotech.com
When Peekskill’s Small Businesses Are Left Behind

Opinion > Peekskill Brewery's former owner says a $100,000 city grant proved worthless in trying to save the popular restaurant

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Sep 8 • 10:15 AM EDT • Business • peekskillherald.com
BUSINESS Katie Scheuber showcases their unique storytelling with Stay Tuned Productions

Almost 12 years ago, nonbinary lesbian Chicago documentary filmmaker and photographer Katie Scheuber created Katie Makes Films video, a production company to showcasing their love of visual storytelling, while still working as a social worker. In 2022, Scheuber’s wife Noemi Heras encouraged them to do the video work full time. Last year Scheuber created Stay Tuned […]

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Sep 8 • 10:04 AM EDT • Business • windycitytimes.com
'T Nation': More men turning to testosterone replacement therapy. What it means for health

In collaboration with the Hearst magazine, "Men's Health," WBAL-TV 11 News examines the increase in testosterone replacement therapy, and what it means for men.

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Sep 8 • 9:56 AM EDT • Health • wbaltv.com
Deconstructing LSD for Therapeutic Discoveries

UC Davis researchers have stripped down LSD to the base features responsible for its hallucinogenic and therapeutic effects.

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Sep 8 • 9:30 AM EDT • Science • ucdavis.edu
Ryan Olohan Joins MDCalc as Head of Sales

NEW YORK--(BUSINESS WIRE)--Sep 8, 2026--

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Sep 8 • 9:13 AM EDT • Business • rutlandherald.com
Science ministry to inject $3.49 bl for AI model

South Korea's science ministry plans to invest 4.7 trillion won ($3.49 billion) for a project to develop a homegrown artificial intelligence (AI) model that wil

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Sep 8 • 8:29 AM EDT • Science • koreaherald.com
MDI Health to Honor Mount Desert Nursing Association with 2026 Impact Award

BAR HARBOR—MDI Health will honor Mount Desert Nursing Association (MDNA) as its 2026 Community Partner of the Year during the organization’s Annual Meeting and Community Celebration on Tuesday, September 15. MDNA will receive the 2026 Impact Award in recognition of its longstanding commitment to providing in-home nursing, physical and occupational therapy, and medical equipment to the Island region. By caring for people where they live, MDNA helps patients remain safely and independently at home, providing reassurance and support to their families. “Mount Desert Nursing Association exemplifies the power of community partnership,” said Chrissi Maguire, President and CEO of MDI Health. “Its nurses bring skilled, compassionate care directly into people’s homes, helping patients navigate illness, recovery, and some of life’s most difficult moments. We are deeply grateful for MDNA’s service and the important role it plays in the health of our community.” MDNA works closely with MDI Health providers and care teams to support continuity of care following hospitalization, surgery, illness, or changes in health. Its personalized services extend care beyond the hospital and help ensure patients receive the support they need close to home. “For 77 years, MDNA has been here for our community, helping our neighbors recover and remain safely at home. Our long-standing partnership with MDI Health is an important part of making that possible. Together, we help ensure a seamless transition from hospital to home and provide patients with the continued care they need. We are incredibly grateful for this recognition and especially proud of our talented and hardworking team,” said Amy McVety, Executive Director of Mount Desert Nursing Association. The Impact Award will be presented during MDI Health’s Community Celebration from 5 to 7 p.m. at the Bar Harbor Club. The event will also recognize outstanding employees, volunteers, and trustees; celebrate MDI Health’s achievements over the past year; and mark a transition in Board leadership as Madeleine Braun, PhD, MBA, prepares to succeed Martha Wagner, PhD, as chair. The celebration will feature music, refreshments, the MDI Health Auxiliary Raffle, and a cash bar. MDI Health’s Annual Business Meeting will take place from 3:30 to 4 p.m. via Zoom. These events are free and open to the public, but space is limited. To reserve your spot, contact Patrianna Anderson at 207-288-5082, ext. 1432, or visit mdihospital.org/communitycelebration. Subscribe Share Leave a comment

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Sep 8 • 8:19 AM EDT • Health • barharborstory.substack.com
Monday Night Therapy: Week 2 Nebraska vs Bowling Green

Monday Night Therapy recaps Nebraska’s 49-21 victory over Ohio while looking ahead to Bowling Green. Although the Huskers won comfortably, the discussion emphasizes that the game was far from a dominant performance early on. Nebraska struggled with penalties, committing nine for 65 yards, while the secondary surrendered an immediate touchdown because of a blown coverage. […]

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Sep 8 • 8:11 AM EDT • Sports • sports.yahoo.com
RingCentral Named to Business Insider America's Most Innovative Businesses 2027 List

BELMONT, Calif.--(BUSINESS WIRE)--Sep 8, 2026--

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Sep 8 • 8:03 AM EDT • Business • rutlandherald.com
Yakima County's second large-scale solar facility is online

Roughly 3 1/2 years after his predecessor approved it, Washington Gov. Bob Ferguson was among 50 people celebrating in a remote corner of Yakima County as the Ostrea Solar project

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Sep 8 • 8:00 AM EDT • Business • yakimaherald.com
Hovione Appoints Stefan Doboczky as Chief Executive Officer

ZUG, Switzerland--(BUSINESS WIRE)--Sep 8, 2026--

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Sep 8 • 7:17 AM EDT • Business • rutlandherald.com
World shares and US futures decline, while oil prices press higher

World shares and U.S. futures have fallen as flaring conflict in the Middle East pushes oil prices higher. China said that its exports jumped 25% year-on-year in August, driven by

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Sep 8 • 5:59 AM EDT • Business • yakimaherald.com
WATCH | Mobile speech therapy business ‘Speech on the Spot’ helps meet families needs

Stepping inside Speech on the Spot, a mobile therapy business, visitors are greeted by bus walls decorated with stickers of sunshine, clouds and the phrase "Imagination Blooms."

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Sep 8 • 5:04 AM EDT • Business • hotsr.com
Brenda Lucas: Community news for Tuesday, Sept. 8

Click for community news in the Huntington, West Virginia, and Tri-State area.

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Sep 8 • 4:45 AM EDT • Entertainment • herald-dispatch.com
Globality Launches Glo 2.0, the First Fully Autonomous Sourcing Platform

LONDON--(BUSINESS WIRE)--Sep 8, 2026--

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Sep 8 • 3:07 AM EDT • Business • rutlandherald.com
Asian shares and US futures decline, while oil prices press higher

Asian shares and U.S. futures have fallen as flaring conflict in the Middle East pushes oil prices higher. China said that its exports jumped 25% year-on-year in August, driven by

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Sep 8 • 3:01 AM EDT • Business • yakimaherald.com
Parties across continents launch dialogue in Seoul as politics fractures, challenges converge

Political parties divided by geography and ideology came together in Seoul on Monday around a shared premise: Even as politics grows more fragmented and polariz

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Sep 8 • 1:55 AM EDT • Politics • koreaherald.com
GenSight Biologics Provides September 2026 Business Updates

PARIS, September 08, 2026--Regulatory News: GenSight Biologics (Euronext: SIGHT, ISIN: FR0013183985, PEA-PME eligible), a biopharma company focused on developing and commercializing innovative gene therapies for retinal neurodegenerative diseases and central nervous system disorders, today provided business updates covering the summer of 2026 and confirmed the publication date for the Company’s financial statement covering the first half of 2026.

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Sep 8 • 1:30 AM EDT • Business • finance.yahoo.com
Hendrickson: Taxpayer protections vital for Iowa’s business climate

This November, Iowans will be asked to vote on a simple constitutional amendment that would make it more difficult for the legislature to increase income taxes. Specifically, the amendment would

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Sep 8 • 1:30 AM EDT • Business • telegraphherald.com
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Flowers: Surrounded by love, Dolly Parton defied politics

Being a good person does not mean you are universally beloved.

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Sep 8 • 1:30 AM EDT • Politics • telegraphherald.com
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NIPPON KINZOKU Exhibits at “electronica India 2026”

TOKYO--(BUSINESS WIRE)--Sep 8, 2026--

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Sep 8 • 12:02 AM EDT • Business • rutlandherald.com
Ngarlawangga Aboriginal Corporation and Rio Tinto sign Interim Modernised Agreement

KARRATHA, Australia--(BUSINESS WIRE)--Sep 7, 2026--

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Sep 7 • 8:02 PM EDT • Business • rutlandherald.com
Does Medication Abortion Cause An Increase In Mental Health Problems?

A new study published in JAMA Psychiatry looked at medication and procedural abortion and the risk of psychotropic medication use. “We examined whether medication or procedural abortion increased risk of mental health medication use,” study author Julia Steinberg told us. Steinberg is Associate Professor in the Department of Family Science School of Public Health at the University of Maryland. "Based on previous research we have conducted, we did not think medication or procedural abortion would increase risk of mental health medication use.”

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Sep 7 • 8:00 PM EDT • Health • theravive.com