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Saints great Joe Horn takes his place in Louisiana Sports Hall of Fame
Joe Horn, one of the best receivers and most charismatic players in New Orleans Saints history, officially joined the Louisiana Sports Hall of Fame.
Leo XIV’s second “business” consistory produced few headlines, but that’s by design
On Saturday, Pope Leo XIV brought an end to the second extraordinary consistory of his pontificate. The meeting of cardinals was not very exciting, which might have been the point.
How we became Broncomaniacs
Here’s how many of us became Broncomaniacs. Share your origin story!
Rep. Ryan rejects rolling back of PFAS cleanup at Stewart air base
Pat Ryan, a Democrat who represents New York’s 18th Congressional District, says the Department of Defense is looking to reduce statutory reporting requirements for PFAS at military installations.
Up Close: Mamdani marks big political victory in New York City primaries
Up Close: Liz Cho sits down with the political team to discuss the New York City primaries and the ongoing battle over horse carriages in Central Park.
Summer Blockbuster Entertainment
“It’s summertime and the living is easy,” those words sung by Ella Fitzgerald in the 1960s might not ring as true in 2026, but summertime should still be the time […]
Iran Might Be The Unluckiest Sports Team Ever
After two late goals in another game sealed Iran’s fate, Team Melli was left to rue one of the most brutal exits in World Cup history.
Nest’s quest to fix your thermostat
On Version History: What “the iPod of thermostats” really means.
Common pesticide linked to more than double the risk of Parkinson’s disease
Scientists at UCLA have linked long-term exposure to the pesticide chlorpyrifos with a sharply increased risk of Parkinson’s disease. People exposed to the chemical near their homes were more than twice as likely to develop the condition. Laboratory studies showed that chlorpyrifos damages dopamine neurons and interferes with the brain’s ability to remove toxic protein buildup.
The Politics of the Instagram Story
Drive yourself crazy for the low price of $3.99 a month!
Popular 9-season sitcom losing its streaming home at end of the summer
The Emmy-award winning series is regarded as as one of the most iconic shows in television history.
🥜 Still nutty after 50 years
Center City snack shop Nuts To You marks 50 years in business and looks to TikTok for sustained growth. Plus: Olney update here TK, and we compare Revolutionary history in Philly vs Boston.
Carman: Tuesday’s election is more than just a primary. It’s a colossal opportunity to change history.
The template for tyrants goes back at least to Ancient Rome and, as Nero discovered, generally ends badly.
Juventus hold exploratory talks for Soule’s return
Matias Soulé is among the candidates to leave Roma in the coming days and be sacrificed on the altar of capital gains. The Argentine winger isn’t pushing to leave; on the contrary, he’s stalling....
📝 2026 World Cup, overnight round-up
Every morning, OneFootball will bring you a full recap of the night at the World Cup. The can't-miss story of the nightThat's it, the group stage of this World Cup is now officially over, and the hea...
BET Awards: Druski to make history as youngest host as show honors Lauryn Hill and Teyana Taylor
Druski will make history as the youngest host of the BET Awards on Sunday.
BET Awards: Druski to make history as youngest host as show honors Lauryn Hill and Teyana Taylor
Druski will make history as the youngest host of the BET Awards on Sunday.
BET Awards: Druski to make history as youngest host as show honors Lauryn Hill and Teyana Taylor
Druski will make history as the youngest host of the BET Awards on Sunday
BET Awards: Druski to make history as youngest host as show honors Lauryn Hill and Teyana Taylor
Druski will make history as the youngest host of the BET Awards on Sunday.
San Antonio Pride festival celebrates LGBTQ+ community, raises money for local nonprofits
Thousands of people were expected at Crockett Park on Saturday for the Pride Bigger Than Texas Festival, an eight-hour celebration of LGBTQ+ history, resilience and community support.
Gunnar gives back: O's shortstop surprises local kid with specialized cleats
BALTIMORE -- The story of 11-year-old Declan Lefevre’s youth baseball career is inspirational. When Declan was about 4 years old, a doctor noticed his legs were different lengths. And it wasn’t something he would grow out of, either, which is something his parents -- father Jeff Lefevre and mother Nichole
Walker Buehler Admits He ‘Especially’ Wants to Beat Dodgers
The Dodgers lost the series opener to the Padres, a game with a ton of storylines, including Walker Buehler facing his former team.
Rangers Down Blue Jays 7-4 to Clinch Series Victory
The Texas Rangers took down the Toronto Blue Jays 7-4 to clinch a series victory and pull one game within .500.
Why soccer is life - Live Updates
“Sport is never just about sport. It is about storytelling and national storytelling,” says acclaimed playwright.
The Chicago Bears are getting their own Hallmark Christmas movie
The Chicago Bears are the latest NFL franchise to get the Hallmark Christmas movie treatment. The team announced Thursday that it is partnering with Hallmark Media, the NFL, and Skydance Sports for Holiday Touchdown: A Bears Love Story, which will premiere during Hallmark Channel’s 17th annual Countdown to Christmas programming event this holiday season. “My…
Everything we know about Taylor Swift and Travis Kelce’s wedding
NEW YORK — There are more people ostensibly invited to celebrate the love story of Taylor Swift and Travis Kelce than there are tidbits of publicly available information about the
Vancouver turns its Science World museum into a giant 17-story soccer ball for the World Cup
It started with a whimsical idea
Vancouver turns its Science World museum into a giant 17-story soccer ball for the World Cup
It started with a whimsical idea.
Vancouver turns its Science World museum into a giant 17-story soccer ball for the World Cup
It started with a whimsical idea. Why not transform the landmark Science World museum in downtown Vancouver, the geodesic dome-topped building not far from BC Place stadium, into a gigantic 17-story soccer ball for the World Cup?
Vancouver turns its Science World museum into a giant 17-story soccer ball for the World Cup
It started with a whimsical idea. Why not transform the landmark Science World museum in downtown Vancouver, the geodesic dome-topped building not far from BC Place stadium, into a gigantic
Scientists finally explain why these wild boars stay more radioactive than Chernobyl's wolves - Futura-Sciences
What explains this surprising finding? The answer appears to be a complex mix of history, ecology, and diet. Bavaria’s wild boars mainly feed on underground fungi that absorbed radioactive fallout from both the notorious Chernobyl disaster and Cold War-era nuclear testing. Unlike wolves, which sit higher on the food chain...
Millions drop Obamacare coverage after subsidies expire, costs rise
New federal figures show that about 3 million fewer people had Affordable Care Act health insurance plans in February compared with the same time last year
HISTORY IN THE MAKING: A RECORD-BREAKING OPENING DAY AT THE PAN AMERICAN ATHLETICS CHAMPIONSHIP MEDELLÍN 2026
The Pan American Athletics Championship delivered everything the Americas had been waiting […]
Your health insurer shouldn’t decide your treatment plan. That’s what your doctor (and possibly AI) should be doing.
With a digital health record, clinicians and AI-driven diagnostic tools would be able to see your full health history — and then make better decisions.
My Boyfriend Said His Family Friend Is Like a “Sister” to Him. Uh, That’s Not What His Computer History Says.
He violated everyone's trust with this.
Caesars Entertainment (CZR) Expands In Maine Online Gaming, Is The Stock Already Fully Valued?
Caesars Entertainment expands digital footprint with Wabanaki Nations partnership Caesars Entertainment (CZR) is extending its partnership with three Wabanaki Nations to include online casino gaming in Maine, targeting a potential 2026 iGaming launch, subject to regulatory approvals. See our latest analysis for Caesars Entertainment. Caesars Entertainment shares have climbed over recent months, with a 90 day share price return of 16.79% and year to date gain of 28.14%. However, the 5 year...
Women Over 50 Aren't Just Starting Businesses. They're Redefining Work.
Women over 50 are starting businesses, but the bigger story is how they're redefining work through greater flexibility, purpose, and control over their careers.
Rank the Derek Hill catch in Phillies history
It’s got to be up there
Cowboys Weekend Headlines: History's brink, Quinnen, Parker dilemmas
The Cowboys are looking to avoid an inglorious feat in 2026, while there are close eyes on two key components in the fight.
World Cup: Reijnders and Ake involved in Netherlands victory
Tijjani Reijnders and Nathan Ake eased past Tunisia in a 3-1 victory to top Group F.The two City stars started brightly for their nation and it wouldn’t be long until the early pressure paid off.Fol...
No debut, but loud cheers: Belfast crowd shows love for Vaibhav Sooryavanshi
Teenage sensation Vaibhav Sooryavanshi's India debut is still pending, but the focus shifted to Ireland's historic 34-run victory in the first T20I. Despite the loss, Shreyas Iyer vowed a strong comeback. Ireland's debutants impressed, with Jai Moondra and Matt Hollard making immediate impacts, while Abhishek Sharma's quickfire fifty wasn't enough for India.
🗞 Today’s back pages: Baena downs Uruguay, the Dembélé show...
Spain’s victory over Uruguay dominates the sports newspaper headlines, but let’s take a look at how the main newspapers around the world are covering it.MARCAASMundo DeportivoSPORTL'EquipeSuperdep...
Mamdani takes victory lap on rent freeze
In February, the mayor appointed six members to the nine-member committee just as this year’s process was set to start.
Local business celebrates 10 year anniversary with $5,000 in cash prizes up for grabs
It is a celebratory feat for any small business to successfully reach 10 years in operation.To mark their 10 year anniversary, Escape It Grandview will be host
Tackling the Politics of the World Cup
The soccer tournament has brought a flood of political story lines.
I Went From Bedside Nurse to Business Owner By Turning a Hobby Into a Home Micro-Factory That Makes Over $100K a Year
Eric Street followed his crafting passion into business.
Goddess of Victory: Nikke x Persona 3, Persona 4 and Persona 5 Collaboration Teased
A teaser trailer has been uploaded teasing a collaboration between mobile and pc game Goddess of Victory: Nikke and the Persona series.
France's Ousmane Dembélé records second-fastest hat trick in World Cup history in 4-1 win over Norway
UC San Diego hosts free Comic-Con events, intersecting health and science through fiction
UC San Diego is holding a badge-free series of comic and science-inspired events in tandem through The Science of Story, from July 21-26.
Deb Haaland Outlines Small Business Agenda in Address to Albuquerque Chamber
Native Vote 2026 Democratic gubernatorial nominee Deb Haaland (Laguna Pueblo) on Thursday outlined her vision for making New Mexico more welcoming to entrepreneurs and small businesses during an address to the Greater Albuquerque Chamber of Commerce, pledging to reduce regulatory barriers while investing in education, public safety, and economic development. Drawing on her own experience […]
The Year 536 AD Was So Bad It May Have Been the Worst Time in Human History to Be Alive
Volcanoes, famine and plague made 536 a leading candidate for history’s worst year.
Factory Entertainment Announces Three More STAR TREK Collectibles, Including Gold-Pressed Latinum Bars
Factory Entertainment today unveiled three more STAR TREK replicas, including bars of gold-pressed latinum and Eline’s necklace from “The Inner Light”
Windows 11 is getting redesigned taskbar settings in new build
Microsoft is giving Windows 11 redesigned taskbar settings, and the changes are already available for testing in the latest build.
'The Bear' ending explained – Jeremy Allen White, cast unpack finale
Warning: This story contains spoilers from the Season 5 finale of “The Bear,” now streaming on Hulu. Clear the plates and pack the linens – “The Bear” has served its
An Incomplete History of Seattle Sports
Sonics, Seahawks, Sounders, Storm, Steelheads, Mariners, Kraken, and more.
Master Inventor Hoffman Turns Chemistry Into Capability | Johns Hopkins University Applied Physics Laboratory
Christopher Hoffman has been recognized as a Johns Hopkins APL Master Inventor, a distinction earned through a career spent asking a simple question: What can chemistry can do to solve a real-world problem?
TLC stage musical “CrazySexyCool” reveals exclusive first look images of T-Boz, Left Eye, and Chilli
The 1990s girl group gets their story told on stage.
Vance Downplays Watergate and Compares Himself to Nixon
The vice president said that the scandal that ended Richard Nixon’s presidency would be “like a 12-hour news story” if it happened today and that the “deep state” had taken down Nixon.
Why Your Nighttime Dreams Are So Weird—Science Finally Has the Answer - Futura-Sciences
The Secret Life of Dreams: Not Just Random Nonsense Remember the dream you had last night? Maybe you’re left with just a trace—a sweet feeling, maybe, or a strange discomfort. But there’s rarely a story you could actually retell. Because, in the end, a dream is a deeply personal experience....
How PENN’s US$360 Million Aurora Resort Shift At PENN Entertainment (PENN) Has Changed Its Investment Story
PENN Entertainment has opened the US$360 million Hollywood Casino and Hotel Aurora, replacing its former Fox River riverboat with a 388,500-square-foot, 24/7 land-based resort featuring over 1,000 slots, 50 table games, a sportsbook, 226-room hotel, spa, event center, and extensive dining options. The Aurora project, which created around 700 permanent roles and mirrors PENN’s broader shift into higher-amenity land-based properties, highlights how the company is reinvesting heavily to refresh...
Nintendo Switch 2 ends first full year in the U.S. at nearly 6 million units sold, second fastest-selling video game system
Following the latest U.S. sales report from Circana, we have information about the first full-year sales of Nintendo Switch 2. The console ended its first twelve months at 5.9 million units sold. According to Circana, it’s the second fastest-selling video game system in the U.S. with tracked history dating back to 1995. The only other platform to outdo it was...
Who are Texas A&M's All-Time Quarterback recruits?
According to 247Sports, here are the top 10 ranked Texas A&M quarterbacks recruits in program history.
Remembering Victory Stadium: How Roanoke’s lost landmark changed sports and civil rights
It’s been 20 years since Victory Stadium was demolished, but the memories and legacy remain alive in Roanoke.
Tigers host the Astros on home losing streak
The Detroit Tigers are looking to stop their three-game home slide with a victory against the Houston Astros
Hollywood gets into the microdrama race as mobile-first storytelling draws stars and major studios
Mobile-first serialized storytelling is rapidly becoming one of entertainment's fastest-growing businesses.
Hollywood gets into the microdrama race as mobile-first storytelling draws stars and major studios
While much of Hollywood was consumed by the streaming wars, Issa Rae was studying a different mode of entertainment thousands of miles away: microdramas. No stranger to creating a successful online s...
Q1 Earnings Highlights: Sphere Entertainment (NYSE:SPHR) Vs The Rest Of The Consumer Discretionary - Leisure Facilities Stocks
Earnings results often indicate what direction a company will take in the months ahead. With Q1 behind us, let’s have a look at Sphere Entertainment (NYSE:SP...
JD Vance says Nixon’s Watergate scandal would be ‘12-hour news story’ today
Vice-president declares admiration for 37th president and claims Nixon and Trump targeted by ‘deep state’ forces
Politics Chat, June 25, 2026
A newsletter about the history behind today's politics.
UCLA comparative literature department to offer health humanities minor in fall
UCLA will offer a minor in health humanities starting this fall. The minor, housed under the comparative literature department, is an interdisciplinary program that examines how health and medicine are shaped by literature, culture, history and social experience, according to the department’s website.
Larry David and Barack Obama's American history show is deeply cringe
For Larry David and Barack Obama, history is a laughing matter. And they've got the sketch comedy show to prove it.
Vance, an admirer of Richard Nixon, says Watergate would be 'a 12-hour news story' today
Vice President JD Vance says the Watergate scandal that brought down President Richard Nixon would have been a blip in today’s news cycle
Golden State Valkyries employee named in Sports Business Journal's Forty under 40 list
The Golden State Valkyries have created a winning culture on and off the court. After making WNBA history last season becoming the first expansion team to reach the playoffs, the success is also extending throughout the organization.
Granger family pledges largest gift in history of UM-Health Sparrow
The Granger family has pledged the largest gift in University of Michigan Health-Sparrow history for a new behavioral health hospital.
Cowboys countdown to kickoff: Top 100 iconic games
We countdown 100 days until kickoff with a series of the most iconic games in Cowboys history. Today is Day 80
Making Our Own Luck
We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.
Renewed Dansby Swanson makes Cubs history with 15 RBI across 3 games vs. Mets, including 11 in doubleheader
How Caesars’ Expanded Tribal iGaming and Community Partnership Could Shape Caesars Entertainment (CZR) Investors’ Outlook
In June 2026, Caesars Entertainment Inc. announced that it had expanded its partnership with three Wabanaki Nations in Maine to cover online casino gaming, aiming to launch Caesars Palace Online Casino, Caesars Sportsbook & Casino and Horseshoe Online Casino in 2026, subject to regulatory approval and integrated with Caesars Rewards and a universal digital wallet. A distinctive element of this agreement is Caesars’ commitment to employ and train tribal members while providing financial...
Dennis Krause Blog: Giannis is one of Wisconsin's best ever sports figures
Simply put, Giannis is on the short list of the most important sports figures in this state's history.
Mars Meets The Seven Sisters, In Astronomical Event You Won't See Again Until 2034
Mars meets the Pleiades this weekend, the subject of what may be humanity's oldest story.
MIT in the media: Exploring how curiosity-driven science is an essential ingredient in America’s success
“Scientific American” showcases the history and future of America’s scientific engine, highlighting promising young scientists and icons at MIT and beyond.
Embodying the Moment: Paloma Elsesser On Beauty, Bodies and Business
The model and muse explained her supermodel origin story and her plans for her next act onstage at The Business of Beauty Global Forum.
Another look at carrots and eyesight; how to get more fiber; why mosquitoes bite some people and not others; plus other stories with Vanderbilt Health sources
AARP reporter Stacey Colino interviewed Milam Brantley, MD, Associate Professor of Ophthalmology and Visual Sciences, in 2020 for a story about whether eating carrots can improve vision. Sacramento Bee reporter Samantha Agate has now used Brantley’s comments in an AI-curated story created by content specialists on the same topic that has been picked up by MSN and others. Prevention magazine interviewed Heidi Silver, RD, PhD, Founding Director of the Vanderbilt Diet, Body Composition, and Human Metabolism Core, for a story about the importance of fiber and how people can get more of it in their diet. William Schaffner, MD, Professor of Preventive Medicine, was quoted by several news outlets about public health issues, including: Women’s Health (tick bites and alpha-gal syndrome); The Washington Post (tetanus); and Healthline (why mosquitoes prefer to bite some people and leave others alone). A visit to Monroe Carell Jr. Children’s Hospital at Vanderbilt by some Banana Ball baseball players was covered by The Tennessean and WZTV Fox 17 News, and The Tennessean’s story was also picked up by Yahoo! Sports. Clarksville Now published a story written by the Montgomery County Economic Development Team, whointerviewed Bradley Stancombe, MD, professor of Clinical Pediatrics, Vanderbilt Neonatology, about the new energy of Vanderbilt Clarksville Hospital and how the facility is recruiting physicians. Healio Allergy/Asthma group editorial director Richard Gawel interviewed Mark Rolfsen, MD, Clinical Fellow in the Division of Allergy, Pulmonary and Critical Care Medicine, for a story about his presentation at the American Thoracic Society meeting on metal health outcomes following ICU discharge. Nashville Scene reporter Hannah Herner interviewed James Crowe, MD, Director of the Vanderbilt Center for Antibody Therapeutics, for a story about his efforts to prepare for the next pandemic by isolating antibodies that can neutralize dangerous viruses. Medscape reporter Kathleen Doheny interviewed Neesha Choma, Associate Chief of Staff of Vanderbilt University Hospital, for a story about how hospitals can reduce readmissions.
Supreme Court sides with big business in Roundup cancer risk fight
The ruling is also a victory for the Trump administration and a defeat for the Make America Healthy Again movement.
Supreme Court sides with big business in Roundup cancer risk fight
The ruling is also a victory for the Trump administration and a defeat for the Make America Healthy Again movement.
Make/Films opens new Lancaster city studio in Stadium District
Make/Films — the studio that brought a story about a Garden Spot teacher to movie theater screens nationwide — recently tripled its space with a new studio.
Ohio State–led team secures NSF award to advance to next phase of the National Quantum Virtual Laboratory program
The Ohio State University is strengthening its growing prominence in quantum science, technology, and education with a $4 million, two‑year Phase II design award from the U.S. National Science Foundation (NSF) to advance a national effort focused on next‑generation quantum sensing.The funding is helping to bring together top researchers and ...
The Pick Is In: Hallmark Media, NFL and Skydance Sports partner with the Chicago Bears for Holiday Touchdown: A Bears Love Story set to premiere during Hallmark Channel’s 17th annual Countdown to Christmas programming event
Hallmark Media, NFL and Skydance Sports on Thursday announced that the Chicago Bears have been drafted for Holiday Touchdown: A Bears Love Story, the third all-new original movie in the successful franchise, set to premiere later in 2026 during Hallmark C
Could the history of Mars be set in stone? Meteorite discovery may offer clues to Red Planet's past
Garnet found in a 4.4-billion-year-old meteorite gives potential insight into the history, development and geological processes of Mars.
Experienced Vikings Executive Says Goodbye
The termination of Kwesi Adofo-Mensah in January has led to an avalanche of front office changes in the Twin Cities. […]
After More Than a Decade of Waiting, ‘GTA VI’ Is Finally Around the Corner
We’re finally getting ‘Grand Theft Auto VI,’ poised to be one of the largest gaming releases in history.
What we know about Trump’s Great American State Fair
The Trump administration’s 16-day-long Great American State Fair has begun, offering visitors to the National Mall in Washington, DC, the chance to visit pavilions showcasing every US state and territory.
World Cup: can big sports events bring us together? Recent history says yes
Although fleeting, sporting events have the enduring power to crumble divisions and highlight the beauty of kinship
Lewis Hamilton's Barcelona win draws Ferrari warning from Guenther Steiner
Guenther Steiner has urged Ferrari to stay grounded and build on Lewis Hamilton’s Barcelona victory
Rubio reassures Gulf allies as US-Iran talks advance
Tehran has already portrayed the deal as a victory
Only Donald Trump could make America’s special 250th birthday all about him
The milestone called for the epic vision of a JFK or the soaring oratory of a Barack Obama. Instead it got a Trump rally
Stubborn, arrogant, a genius: France’s De Gaulle epic shows up the tepidity of our politics
The man who led Free France during Nazi occupation was single-minded to the point of obstinacy. But he believed in his own power to make history, says Guardian Europe writer Alexander Hurst