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Bank of America community roundtable highlights sales tax increase, small business struggles

Business and government leaders also discussed hiring trends and the importance of the Charlotte Douglas International Airport.

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Jun 26 • 5:09 AM EDT • Business • charlotteobserver.com
The nation’s cartoonists on the week in politics

Every week political cartoonists throughout the country and across the political spectrum apply their ink-stained skills to capture the foibles, memes, hypocrisies and other head-slapping events in the world of politics. The fruits of these labors are hundreds of cartoons that entertain and enrage readers of all political stripes. Here's an offering of the best of this week's crop, picked fresh off the Toonosphere. Edited by Matt Wuerker.

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Jun 26 • 5:06 AM EDT • Politics • politico.com
Cabo Verde Is a Breakout Star of the World Cup. So Is the Family-Owned Business That Designed Its Jerseys

After more than three decades manufacturing apparel, Capelli Sport co-founder and CEO George Altirs found his company’s biggest billboard yet—3,500 miles away from his midtown Manhattan office.

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Jun 26 • 5:00 AM EDT • Business • inc.com
Online retailer John's Crazy Socks relocates to Huntington in effort to turn around business

The company's core mission is to create employment opportunities for people who face barriers to work because of disabilities.

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Jun 26 • 5:00 AM EDT • Business • newsday.com
Ohio Black-owned businesses, payroll has increased, bringing bigger share of economy to group

According to analysis of national census data, black-owned businesses in Ohio continue to increase payroll, and drive jobs and income in the state.

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Jun 26 • 3:50 AM EDT • Business • ohiocapitaljournal.com
Hall of Fame GM Expresses Concerns About Extending Vita Vea

As a lucrative "hold-in" intensifies, Bill Polian warns that committing massive capital to an aging nose tackle could backfire for a Tampa Bay roster already in transition.

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Jun 26 • 3:34 AM EDT • Sports • sports.yahoo.com
What we learned as Bryce Harper caps Phillies' shocking comeback trilogy

The Phillies erased another five-run deficit, rallied late again and reached the season’s halfway point with another reminder of how much has changed.

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Jun 25 • 9:50 PM EDT • Sports • nbcsportsphiladelphia.com
Mental health as both outcome and determinant in climate adaptation

Nature Climate Change - Mental health should not be viewed solely as a passive outcome of climate adaptation. Rather, it serves as a key determinant of cognitive capacity and shapes the...

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Jun 25 • 8:00 PM EDT • Health • nature.com
21ALIVE SPORTS DIGITAL EXCLUSIVE: Loyer to the Clippers, TinCaps find second half success

21Alive Sports Director Andy Newman and Weekend Sports Anchor Nia Hinson catch you up on this week’s sports news.

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Jun 25 • 7:02 PM EDT • Sports • 21alivenews.com
Tennessee court temporarily blocks state health officials from sharing undocumented ill children’s information

The “state cannot go forward with the policy” until the judge makes a final decision, said the head of the Tennessee Justice Center.

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Jun 25 • 5:37 PM EDT • Health • nbcnews.com
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Project manager says America’s Time Capsule is a ‘gift to the future’

The vessel will move from Washington to Philadelphia starting Friday.

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Jun 25 • 4:53 PM EDT • Politics • spectrumnews1.com
Making Our Own Luck

We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.

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Jun 25 • 4:48 PM EDT • Science • goodscience.substack.com
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Transcription by Ben Lerner wins Orwell prize for political fiction

Judging chair calls Lerner’s novel a ‘funny, brainy and timely’ study of our appetite for technology, while Karen Bartlett wins the nonfiction prize for The Escape from Kabul

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Jun 25 • 4:15 PM EDT • Politics • theguardian.com
Trump’s fixation on election overhaul bill derails GOP agenda on Capitol Hill

A nasty feud over President Donald Trump’s elections overhaul push has further crippled an already-dysfunctional Congress, leaving Republicans unable to move on critical elements of their agenda.

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Jun 25 • 4:10 PM EDT • Politics • cnn.com
Lizzy Caplan, John Stamos Movie 'Drag' Gets Winter 2027 Release

Briarcliff Entertainment has dated the Danny DeVito produced 'Drag' starring Lizzy Caplan, Lucy DeVito and John Stamos for Jan. 29, 2027.

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Jun 25 • 2:59 PM EDT • Entertainment • deadline.com
Adidas’ NIL pipeline is producing NBA rookies who already know the business

Mikel Brown Jr. reached the NBA with a head start few rookies have. Long before being selected sixth overall by the Brooklyn Nets at Tuesday’s NBA Draft, the 20-year-old guard had been embedded in Adidas’ ecosystem through a name, image and likeness deal that began in high school. “By the time our athletes walk across […]

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Jun 25 • 2:30 PM EDT • Business • andscape.com
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Trump Keeps Undercutting Republicans’ Message, Squandering His Own Trifecta

Divisions between the president and his party on Capitol Hill have muddled Republicans’ midterm pitch to voters, and have crippled the G.O.P. at what should be the peak of its power.

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Jun 25 • 2:04 PM EDT • Politics • nytimes.com
Honoring the best in small business

Fifth Street Renaissance, Resource One, Cured Catering, and ChangeBridge Consulting are all honored.

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Jun 25 • 1:58 PM EDT • Business • capitolcitynow.com
Kurt Zellers departs as Minnesota Business Partnership CEO in latest business lobby shuffle

A sudden departure of Kurt Zellers at the Minnesota Business Partnership is just one of the changes ahead for business advocacy groups in the state.

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Jun 25 • 12:53 PM EDT • Business • mprnews.org
JD Sports Upgrades Listing to Broaden U.S. Investor Access

Shares of JD Sports in the U.S. now trade on the OTCQX exchange from the Pink Limited Market, broadening its access to deeper capital pools.

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Jun 25 • 12:51 PM EDT • Sports • finance.yahoo.com
Two NC lawmakers, a Democrat and a Republican, push Congress to delay SNAP changes

Above the federal penalty threshold, NC could owe $140M a year, putting at risk a program that helps over 1.2 million North Carolinians.

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Jun 25 • 12:49 PM EDT • Politics • newsobserver.com
Game On Retro owner plans entertainment empire expansion, Coram movie theater transformation

Plans include opening a new arcade, store and transforming a shuttered movie theater in Coram.

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Jun 25 • 12:32 PM EDT • Entertainment • newsday.com
Tech: House Science advances AI bills

The House Science Committee advanced a bipartisan bill that would codify increasingly prominent artificial intelligence oversight work being done by the Commerce Department.

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Jun 25 • 12:04 PM EDT • Science • punchbowl.news
Ranking Big 12 recruiting classes via average commit distance

The Big 12 recruiting landscape continues to change as programs continue to shuffle throughout the conference. Texas Tech is pushing to sign the nation’s No. 1 class in the 2027 cycle and it firmly sits atop the league’s recruiting rankings. The Red Raiders are the only Big 12 team with a top-25 haul, per the […]

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Jun 25 • 11:41 AM EDT • Sports • sports.yahoo.com
Major part of student-loan repayment overhaul is blocked in court

A federal court ruled that the Education Department's proposed borrowing caps for advanced healthcare programs cannot take effect on July 1.

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Jun 25 • 11:10 AM EDT • Business • businessinsider.com
Another look at carrots and eyesight; how to get more fiber; why mosquitoes bite some people and not others; plus other stories with Vanderbilt Health sources

AARP reporter Stacey Colino interviewed Milam Brantley, MD, Associate Professor of Ophthalmology and Visual Sciences, in 2020 for a story about whether eating carrots can improve vision. Sacramento Bee reporter Samantha Agate has now used Brantley’s comments in an AI-curated story created by content specialists on the same topic that has been picked up by MSN and others. Prevention magazine interviewed Heidi Silver, RD, PhD, Founding Director of the Vanderbilt Diet, Body Composition, and Human Metabolism Core, for a story about the importance of fiber and how people can get more of it in their diet. William Schaffner, MD, Professor of Preventive Medicine, was quoted by several news outlets about public health issues, including: Women’s Health (tick bites and alpha-gal syndrome); The Washington Post (tetanus); and Healthline (why mosquitoes prefer to bite some people and leave others alone). A visit to Monroe Carell Jr. Children’s Hospital at Vanderbilt by some Banana Ball baseball players was covered by The Tennessean and WZTV Fox 17 News, and The Tennessean’s story was also picked up by Yahoo! Sports. Clarksville Now published a story written by the Montgomery County Economic Development Team, whointerviewed Bradley Stancombe, MD, professor of Clinical Pediatrics, Vanderbilt Neonatology, about the new energy of Vanderbilt Clarksville Hospital and how the facility is recruiting physicians. Healio Allergy/Asthma group editorial director Richard Gawel interviewed Mark Rolfsen, MD, Clinical Fellow in the Division of Allergy, Pulmonary and Critical Care Medicine, for a story about his presentation at the American Thoracic Society meeting on metal health outcomes following ICU discharge. Nashville Scene reporter Hannah Herner interviewed James Crowe, MD, Director of the Vanderbilt Center for Antibody Therapeutics, for a story about his efforts to prepare for the next pandemic by isolating antibodies that can neutralize dangerous viruses. Medscape reporter Kathleen Doheny interviewed Neesha Choma, Associate Chief of Staff of Vanderbilt University Hospital, for a story about how hospitals can reduce readmissions.

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Jun 25 • 10:56 AM EDT • Health • news.vumc.org
Bungie Hit With Widespread Layoffs As ‘Destiny 2’ Ends And ‘Marathon’ Continues

Destiny 2's end has led to inescapable layoffs at Bungie, which are beginning today as the rest of the studio will now work on Marathon.

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Jun 25 • 10:46 AM EDT • Technology • forbes.com
Service & Solidarity Spotlight: Health Care Professionals in New Jersey Ratify New Contract

Members of United Food and Commercial Workers (UFCW) Local 152 who work at Cape Regional Physicians Associates (CRPA) in New Jersey have secured a powerful new collective bargaining agreement.

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Jun 25 • 10:18 AM EDT • Health • aflcio.org
Former New Orleans Saints receiver Joe Horn ready for induction into Louisiana Sports Hall of Fame

"All the accolades that come behind my career and my work, I'm very humbled by it all"

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Jun 25 • 10:00 AM EDT • Sports • neworleanssaints.com
The Pick Is In: Hallmark Media, NFL and Skydance Sports partner with the Chicago Bears for Holiday Touchdown: A Bears Love Story set to premiere during Hallmark Channel’s 17th annual Countdown to Christmas programming event

Hallmark Media, NFL and Skydance Sports on Thursday announced that the Chicago Bears have been drafted for Holiday Touchdown: A Bears Love Story, the third all-new original movie in the successful franchise, set to premiere later in 2026 during Hallmark C

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Jun 25 • 9:00 AM EDT • Sports • chicagobears.com
Gallery | Jets First Round Rookies Visit Atlantic Health System's Goryeb Children's Hospital

Jets first round picks David Bailey, Omar Cooper Jr. and Kenyon Sadiq visited children at the Atlantic Health System's Goryeb Children's Hospital.

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Jun 25 • 8:06 AM EDT • Health • newyorkjets.com
Everything Announced At The 2026 Capcom Spotlight

Here's a quick recap of the 30-minute broadcast.

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Jun 25 • 8:00 AM EDT • Technology • gameinformer.com
CU Director of Sports Medicine Dr. Eric McCarty Provides Capitol Hill Briefing on College Athletics Landscape

The University of Colorado's Director of Sports Medicine Dr. Eric McCarty was among a prestigious panel of physicians and coaches leading a briefing on Capit...

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Jun 25 • 8:00 AM EDT • Sports • cubuffs.com
How should European scientists respond to the US AI kill switch?

Earlier in June, Europe’s worst fears of technological dependence were confirmed when the White House ordered the AI firm Anthropic to stop non-US citizens using its leading models. This kill-switch moment crystalised anxieties in Brussels that the continent, lagging the US on the creation of leading-edge AI models, is now a technological of vassal of Washington. The shock has specific implications for European scientists and universities. Some governments are now worried that with AI being integrated into labs, Donald Trump now has his finger hovering over an off switch for European science. “Having restrictions on this tool, it can have an impact on our own research,” said France’s research minister, Philippe Baptiste, at the VivaTech conference in Paris on June 18.Baptiste, himself a former academic, said that colleagues in mathematics had recently warned him they were now cut off from leading-edge US models, risking their work. “This model is not available anymore now because of the US restriction, and for the first time this had an impact on mathematics,” a field where large language models (LLMs) are making a significant contribution, said Baptiste. So, should European scientists avoid relying on US models in the future? Or would this be a self-harming overreaction? And how is AI being used in science, anyway? What happened?On June 12, it emerged that Washington, citing cybersecurity concerns, had ordered Anthropic to stop non-US citizens using two models: Claude Mythos 5, and Claude Fable 5, a version of Mythos but with guardrails to prevent abuse. Anthropic said Washington’s concerns were overblown. But forced to follow the order, yet with no way to check who was using the models, the company suddenly shut down access for everyone, US citizens included. There’s still no agreement on how to restore broad access. But last week, Bloomberg reported that select US companies, and the US government, still had access to Mythos despite the ban, but the EU’s cybersecurity agency Enisa had been shut out. Class division of researchersIn the longer term, access outside the US should be restored, said Marcel Salathé, co-director of the AI centre at the Federal Polytechnic School of Lausanne (EPFL), because a permanent restriction would be financially ruinous to US AI firms. “Even Trump will eventually budge to economic pressure,” he said.However, US AI firms might end up operating rather like banks, doing due diligence on users of their leading-edge AI models, he went on.European scientists are unlikely to fall foul of such checks, he said. But having a Chinese postgraduate in their lab, or doing a type of research the US disapproved of, could potentially result in access being denied. “It will create a sort of class division of researchers,” he said. More than frontier modelsHowever, successfully deploying AI in science is about far more than just having access to leading LLMs such as Mythos.Instead, many science-specific tools, most famously Alphafold, which predicts protein folding structures, require “far less” computing power to train than frontier models, well within the capabilities of European supercomputers, according to a recent analysis by the Arq Foundation, a Brussel-based AI think tank. Instead, tools such as Alphafold are possible because certain fields, like protein folding, weather prediction or astronomy, have large, clean, standardised datasets that can be used to train predictive models. Rather than compute, “data is the central constraint for AI for science,” the report says. For example, a less powerful physics model trained on CERN’s data “will be more valuable than the best model without certain data,” said Bengüsu Özcan, author of the report. European advantage?Europe could therefore steal a march by using its scientific data and infrastructure to create models US digital giants cannot. “They might actually match or go even beyond what these big [US] companies are doing,” said Özcan.Indeed, some European start-ups hope to create automated testing labs to create the kind of standardised data that could speed up the discovery of new materials. Materials scientists say there’s currently too little data to train models. AI scientistsHowever, even if the bottleneck for AI in science is often data, rather than compute, being at the mercy of the US for LLM access could still become a problem for European scientists. A new class of “AI scientists” based on leading LLMs is also emerging, Özcan’s report says.Unlike domain-specific tools like Alphafold, these try to automate day-to-day scientific work, by providing an overarching tool that coordinates specific models to synthesise existing literature, generate hypotheses or run analysis of data. The problem for Europe, however, is that these tools are sometimes based on US leading models. Google Deepmind’s AI Co-Scientist, for example, is built on Google’s Gemini LLM. Systematic failureThese scientific automation tools are still in their early stages, and still exhibit “systematic failures on scientific tasks,” Özcan’s report says. One of the problems is that the messy, day-to-day process of scientific discovery is largely not documented, meaning LLMs don’t have a good source of data to learn how scientists actually work. Meanwhile, some tasks, such as literature synthesis, don’t typically require access to leading edge models.However, the performance of AI scientific assistants could improve as companies such as Google pour resources into developing them. Rely on US“Unfortunately, for scientific assistants, there is not much we can do right now except rely on US frontier AI,” said Antoine Bosselut, a natural language processing expert based at EPFL. Chinese-built open models, which can run on local computers, lessening the risk of a shutdown, are touted as one alternative to US dependence. There’s also Mistral, once seen as Europe’s main AI hope, but the Paris-based company has seen its recent models fall behind in performance. But the Chinese alternatives are generally not as capable as US frontier AI models, said Bosselut, unless paired with fiddly, custom tools that allows them to act as independent agents. “Most scientists do not have the time,” he said. Don’t jump ship yetAlthough the kill switch moment is seen a warning shot for European scientists, it doesn’t mean labs should abandon US AI tools immediately. “I do not think the right response is simply to abandon US-based models and systems under the banner of sovereignty or independence,” said Mattias Björnmalm, secretary general of the Cesaer university association. “That would be an overreaction.”Related articlesEuropean sovereignty in AI requires ‘ugly trade-offs,’ say experts Robotic lab start-up makes case for €500M EU-funded materials testing facilityAI in science: is it useful? Instead, European researchers need to ask themselves whether they’re becoming dependent on technology that could be turned off in Washington, said Özcan. “They might not see this today, but they should really start asking this question,” she said. European researchers need a plan B, said Salathé. “I would recommend to every researcher, very proactively explore alternatives.”Own toolsIn addition, Björnmalm and others want European research institutions to develop their own scientific AI tools.Instead of signing AI deals with US digital giants, European universities should be using this money to create their own models, which may end up being superior for research, said Sabine Leonelli, an expert on the use of AI in science at the Technical University of Munich. “Universities in Europe seem to be happy to sign commercial contracts with US companies on the assumption [their AI tools] are better,” she said. But US frontier LLMs are typically opaque, and have been developed without independent scientific input, she said. “This is not good enough for science.”Last year, Swiss researchers released Apertus, an LLM designed to be completely transparent, from its development methods to its training data. The idea is that this makes scientific tools built on top of the model far more reproducible than with closed, commercial alternatives.“Europe needs more of this: serious capacity-building that gives researchers, universities and companies credible options,” said Björnmalm.

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Jun 25 • 8:00 AM EDT • Science • sciencebusiness.net
Inside Notre Dame MBA Global Business Immersion in Santiago, Chile - Notre Dame Business Mendoza College of Business

Global MBA students gain firsthand exposure to global capital markets and international business strategy in Santiago, Chile.

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Jun 25 • 8:00 AM EDT • Business • mendoza.nd.edu
Chicago Cubs news

Dansby Swanson’s five-game hitting streak was capped Wednesday with a grand slam in the 10-3 win over the Mets

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Jun 25 • 8:00 AM EDT • Sports • sports.yahoo.com
Davis just perfected NIMBY politics. Why the rest of the region should care

The neighbors surrounding the 1,800-home Village Farms project voted against Measure V in overwhelming numbers, quashing support elsewhere.

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Jun 25 • 8:00 AM EDT • Politics • sacbee.com
Highest June minimum temperature record broken in Cardiff as ‘savage’ heatwave continues

Thermometer only drops to 23.5C overnight in Welsh capital as climate crisis makes such extreme temperatures more severe and more likely

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Jun 25 • 7:31 AM EDT • Health • theguardian.com
77% of small businesses now use AI regularly. Here’s where they’re starting.

Intuit QuickBooks reports 77% of U.S.

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Jun 25 • 7:00 AM EDT • Business • miamiherald.com
TikTok and YouTube are reinventing sports viewership. Broadcasters are taking note

Leagues, teams and media networks are increasingly meeting younger fans on social media as platforms like TikTok, Roblox and YouTube capture most of their time.

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Jun 25 • 7:00 AM EDT • Sports • cnbc.com
Supporters of KY’s Lee Specialty Clinic supporters want politics put aside to avert cuts

Over 100 people rallied in support of Lee Specialty Clinic in Frankfort Wednesday afternoon and testified on the importance of its services.

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Jun 25 • 6:58 AM EDT • Politics • kentucky.com
Political strategist on the growing tensions between Trump and Senate Republicans

NPR's Michel Martin speaks with political strategist Alex Conant about President Trump's tense meeting with Republican senators on Capitol Hill.

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Jun 25 • 6:46 AM EDT • Politics • npr.org
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Des Bishop turns a turbulent past into comedy in 'Bridge and Tunnel'

Queens-born comic Des Bishop’s new “Bridge & Tunnel” special captures his long, winding journey from Irish stardom back to New York, where he finally finds his fast-paced American voice.

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Jun 25 • 6:00 AM EDT • Entertainment • latimes.com
High costs hurt Wisconsin residents’ health, state report shows

A new report from Wisconsin’s health department examining where the state is winning and losing when it comes to the health of Wisconsinites.

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Jun 25 • 6:00 AM EDT • Health • captimes.com
What are the best businesses in Centre County? Submit your nominations to CBICC

Your input can help recognize a deserving local business or nonprofit organization.

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Jun 25 • 5:13 AM EDT • Business • centredaily.com
Business - Maritime traffic picks up in Strait of Hormuz, but uncertainty lingers
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Jun 25 • 4:50 AM EDT • Business • france24.com
A lack of funding, a glut of stigma: How Ohio LGBTQ+ health outcomes are impacted

For the 1 in 10 Ohioans who identify as LGBTQ+, media representation and social acceptance may have improved, but stigma and discrimination still impact them in large aspects of their lives, including healthcare access.

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Jun 25 • 3:55 AM EDT • Health • ohiocapitaljournal.com
Walmart’s $1.4 billion Vibe.co deal is a direct shot at Amazon’s booming ad business

With a $1.4 billion deal for Vibe.co, Walmart is aiming to capture the ad dollars of smaller brands.

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Jun 25 • 3:00 AM EDT • Business • fortune.com
Politics in the Park: GOP gubernatorial candidates share visions for Wyoming governor

CASPER, Wyo. — Three Republican gubernatorial candidates shared their views on a myriad of topics spanning taxation, energy production, resource rights

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Jun 25 • 12:21 AM EDT • Politics • capcity.news
Sister’s Gift Represents Transplant First at Sutter Health

Photo caption: Dr. Eric Miller adjusts the image focus on the da Vinci 5 robot as he performs Sutter’s first fully robotic living-donor kidney transplant. | June 2, 2026 Sutter’s California Pacific Medical Center (Sutter’s CPMC) in San Francisco has performed its first fully robotic living-donor kidney transplant, marking a significant milestone for the system’s […]

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Jun 24 • 7:52 PM EDT • Health • vitals.sutterhealth.org
The biotech founder asking why good science gets stuck

As an undergraduate, Alinta Furnell led student societies, pitched startup ideas and built biotechnology ventures. Now, the UNSW alumna is investigating one of innovation’s biggest challenges – why so many scientific breakthroughs never make it beyond the lab.

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Jun 24 • 7:00 PM EDT • Science • unsw.edu.au
What Does Success Look Like in 2026 for Dolphins?

After moving on from veterans such as Tua Tagovailoa and Tyreek Hill, the upcoming season is about developing the Dolphins' roster, resetting the culture, and gaining salary cap flexibility for the future. The goal for any NFL team is not just to succeed in the immediate future but to establish a solid foundation for long-term success. After releasing Tagovailoa, Willis became the Dolphins' most significant free agent acquisition after he signed a three-year, $67.5 million contract with $45 million guaranteed.

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Jun 24 • 6:00 PM EDT • Sports • sports.yahoo.com
Political insiders break down New York's 2026 primary election results

David Carlucci and David Catalfamo join Capital Tonight.

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Jun 24 • 6:00 PM EDT • Politics • spectrumlocalnews.com
WATCH: Congress dedicates national time capsule ahead of America's 250th anniversary

The Time Capsule Act, a 2016 law creating the nonpartisan America250 commission mandated that a time capsule be buried in Philadelphia on July 4, 2026, and dug up 250 years later in 2276.

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Jun 24 • 5:34 PM EDT • Politics • pbs.org
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DC Wrap: Trump lashes out over Iran vote; Great American State Fair begins

A look at the day's biggest stories in national politics

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Jun 24 • 5:21 PM EDT • Politics • spectrumlocalnews.com
DC Wrap: Trump lashes out over Iran vote; Great American State Fair begins

A look at the day's biggest stories in national politics

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Jun 24 • 5:21 PM EDT • Politics • spectrumlocalnews.com
Business - Power outages and melting roads: Heatwave strains French infrastructure
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Jun 24 • 4:55 PM EDT • Business • france24.com
Ex-aides win primaries to replace retiring Democratic House members

U.S. Reps. Steny Hoyer and Jerrold Nadler passed the torch Tuesday night to former aides who won the Democratic primaries to replace them on Capitol Hill.

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Jun 24 • 4:40 PM EDT • Politics • pbs.org
The World Cup has been good for Johnson County, many businesses say

“We all have the same opportunities,” one business owner said. “There’s so many opportunities to go out and be proactive.”

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Jun 24 • 4:36 PM EDT • Business • kansascity.com
Mayor David Chait Attends Capital Health's Pride Flag Raising and Juneteenth Ceremonies

Hopewell Township, Mercer County, NJ - Throughout the month of June, Mayor David Chait was honored to join community members at both Capital Health's Pride Flag Raising Ceremony and Juneteen

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Jun 24 • 4:27 PM EDT • Health • hopewelltwp.org
Sabres agree to send Alex Tuch to the Capitals, AP source says

In Buffalo, he had 139 goals and 309 points in 360 games in filling a top-line role.

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Jun 24 • 4:13 PM EDT • Sports • spectrumlocalnews.com
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FMOL Health’s E.J. Kuiper touts $500M in capital spending, strong financials

FMOL Health has committed more than $500 million to capital investments since E.J. Kuiper took over as president and CEO.

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Jun 24 • 3:47 PM EDT • Health • businessreport.com
Tennessee parents, doctors warn of law aimed at excluding ill undocumented children from public medical program

A Tennessee law requires the health department to share the immigration status of a child with state authorities if they’re enrolled in the Children’s Special Services program.

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Jun 24 • 3:13 PM EDT • Health • nbcnews.com
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Pints & Politics with WUNC's Colin Campbell in Pittsboro

To celebrate WUNC's 50th anniversary this year, we're hosting 50 events across North Carolina! Please join us on August 19 at BMC Brewing at The Plant in Pittsboro for Pints & Politics with WUNC Capitol Bureau Chief Colin Campbell! The event kicks off at 6 p.m.We'll chat about all things North Carolina politics, and your first pint will be on BMC Brewing in a special WUNC 50th anniversary pint glass! This event is free and open to the public, but an RSVP is encouraged as space is limited. Please RSVP at the link below to let us know if you are planning to join us. You can also submit a question for Colin in advance when you sign up to attend. We hope to see you soon!> RSVP Here

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Jun 24 • 3:07 PM EDT • Politics • wunc.org
Colombia's vote may reshape the Amazon's future as political winds shift across Latin America

Abelardo de la Espriella, set to be Colombia's president, has intensified debate over the future of the Amazon.

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Jun 24 • 2:11 PM EDT • Politics • newsday.com
BIZNOTES: Three West Seattle business anniversaries

Three West Seattle businesses are celebrating anniversaries: CAPERS HOME: All month long, CAPERS (4525 California SW; WSB sponsor) has been holding their 41st anniversary sale, but there's less than a week left in June, so this is your last call to get in and shop! THE BEER JUNCTION TURNS 16: The Junction's beer shop is celebrating its ...

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Jun 24 • 2:07 PM EDT • Business • westseattleblog.com
SouthCoast offering sports physical clinic

Physicals required for all student-athletes in Georgia

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Jun 24 • 12:47 PM EDT • Sports • wtoc.com
The Midlands has a massive new entertainment center with bowling, food and more

The 44,000-square-foot, $13 million new facility brings bowling, an arcade, a full food menu, multiple bars and more to the Midlands.

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Jun 24 • 12:05 PM EDT • Entertainment • thestate.com
'Fingerprints' of black hole's event horizon detected for first time

Scientists have detected the "fingerprints" of a black hole's event horizon -- the boundary from which nothing can escape -- for the first time, according to research published on Wednesday. The scien...

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Jun 24 • 11:07 AM EDT • Science • yahoo.com
Trump cancels housing bill signing, pressures Congress to pass voter ID law

The bill was supposed to have been signed Wednesday at the Capitol

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Jun 24 • 10:59 AM EDT • Politics • spectrumlocalnews.com
Trump cancels housing bill signing, pressures Congress to pass voter ID law

The bill was supposed to have been signed Wednesday at the Capitol

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Jun 24 • 10:59 AM EDT • Politics • spectrumlocalnews.com
Trump cancels plan to sign major housing bill as he fights with Congress over the SAVE Act

Just hours before heading to Capitol Hill, Trump called the big, bipartisan housing bill Republicans hope to run on in the fall “of minor importance.”

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Jun 24 • 10:42 AM EDT • Politics • nbcnews.com
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Exploring Heat’s search for shooters and what makes sense with roster, finances

A look at the Heat’s search for shooters to put around Giannis Antetokounmpo and Bam Adebayo

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Jun 24 • 10:17 AM EDT • Sports • miamiherald.com
Yankees Rivalry Roundup: Royals drop double-digit runs on Rays

Recapping how the Yankees’ top American League opponents fared on June 23rd.

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Jun 24 • 10:00 AM EDT • Sports • sports.yahoo.com
Trump to sign sweeping bipartisan housing affordability bill into law at Capitol
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Jun 24 • 9:58 AM EDT • Politics • cbsnews.com
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Girls Flag Football is Now OHSAA’s 29th Recognized Sport

OHSAA Board of Directors voted to add girls flag football as a fully sanctioned sport

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Jun 24 • 9:10 AM EDT • Sports • bengals.com
Otto the Orange Levels Up at EA Sports’ Opening Drive

Otto traveled to Chicago to represent the ACC in EA Sports' College Football 27, with the Center for the Creator Economy capturing it all.

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Jun 24 • 9:00 AM EDT • Sports • news.syr.edu
Federal officials plan to offload some warehouses purchased for immigrant detention

U.S. Immigration and Customs Enforcement is retreating from a plan to use warehouses to hold up to 10,000 people on a single site, dropping a key piece of former Homeland Security Secretary Kristi Noem’s $38-billion plan to rapidly expand detention capacity this year.

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Jun 24 • 8:15 AM EDT • Politics • pbs.org
'The Bear' Season 4 recap – What to remember before Season 5

Before your upcoming reservation at “The Bear” allow us to refresh your memory about the previous course, Season 4.

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Jun 24 • 8:00 AM EDT • Entertainment • centraloregondaily.com
Why South Africa’s leopards shrank to half their normal size

A hidden population of South African leopards has revealed a remarkable evolutionary story. Researchers analyzing entire leopard genomes discovered that the Cape Floristic Region’s leopards are not only much smaller than most African leopards, but also genetically distinct after being isolated for roughly 20,000 years. Surprisingly, despite their small population, they have retained much of their genetic diversity.

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Jun 24 • 8:00 AM EDT • Science • sciencedaily.com
AMC Entertainment Crashes 23% Upon Sell of 95.25 Million Shares to Raise $200 Million In Capital

AMC Entertainment stock moves after announcing a 95.25M share offering to raise $200M, primarily to retire its remaining 2027 debt maturity ahead of schedule.

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Jun 24 • 6:57 AM EDT • Entertainment • tikr.com
AI-Powered Emails Are Influencing Politics on Hot-Button Issues

From California to North Carolina, officials weighing policy changes are being inundated with comments via platforms that tout AI capabilities.

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Jun 24 • 6:30 AM EDT • Politics • bloomberg.com
This week in Santa Cruz County business: Capitola Wharf business faces uncertain future; Aptos Village business owners and RTC head to court

A proposed new policy regarding leases of city-owned property has the owner of Capitola Boat & Bait worried her business could be priced off the wharf, Jessica M. Pasko reports in her weekly column.

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Jun 24 • 6:00 AM EDT • Business • lookout.co
Caitlin Clark's argument with her coach went viral. How did Indy sports reporters handle the story?

To anyone who’s familiar with WNBA coverage, it’s no surprise that a recent video of a mid-game disagreement between Caitlin Clark and her coach went viral.

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Jun 24 • 5:00 AM EDT • Sports • indianacapitalchronicle.com
'Rangers close to re-signing McCrorie'

Rangers are closing in on a deal to bring 28-year-old versatile Scotland-capped defender Ross McCrorie back to Ibrox from Bristol City. Rangers Review) Rangers are preparing to submit a formal offer for 22-year-old Dundee centre-back Luke Graham in the coming weeks. Football Insider) Head coach Steven Pressley says Dundee have received "plenty of phone calls" about Luke Graham this summer, but there has been no firm offers for the centre-half who trained with the senior Scotland squad before the World Cup.

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Jun 24 • 3:23 AM EDT • Sports • sports.yahoo.com
Braves blow another one in 7-6 loss to Padres

A wild night at Petco Park was capped off by a walk-off single by way of Manny Machado as the Braves fell to the Padres, 7-6, in 10 innings. This is a bad baseball team at the moment. The second inning was a doozy for both sides. The Braves loaded the bases and cashed in […]

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Jun 24 • 12:56 AM EDT • Sports • sports.yahoo.com
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Two teens accused of theft at Cape Coral business

Two teenagers were arrested on Sunday after they were accused of theft at a business in Cape Coral.

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Jun 23 • 11:53 PM EDT • Business • gulfcoastnewsnow.com
Salt Lake City to begin requiring business licenses for short-term rentals

Utah's capital city is now cracking down on recent short-term rental challenges through an ordinance that will require business licenses to operate them.

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Jun 23 • 9:04 PM EDT • Business • ksl.com
Capital Region individuals arrested in connection to nationwide healthcare fraud crackdown
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Jun 23 • 6:21 PM EDT • Health • cbs6albany.com
Don Toliver expands world tour with first stop at Sacramento’s Golden 1 Center

The ‘Octane’ World Tour’s ‘Nitrous’ expansion will kick off at Sacramento’s Golden 1 Center.

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Jun 23 • 6:08 PM EDT • Entertainment • sacbee.com
AMC Entertainment Holdings (AMC) Is Down 16.5% After Dilutive Debt-Reduction Equity Raise - Has The Bull Case Changed?

Earlier today, AMC Entertainment Holdings announced a registered direct follow-on equity offering of 95,250,000 common shares at about US$2.10 each, aiming to raise roughly US$200.03 million primarily to redeem 6.125% Senior Subordinated Notes due 2027 and for general corporate purposes. This latest capital raise follows AMC’s roughly US$150 million at-the-market equity offering completed in early June, underlining how ongoing balance sheet repair is coming at the cost of further dilution...

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Jun 23 • 5:27 PM EDT • Entertainment • simplywall.st
Meet Caramelo, the Mexico superfan attending his 11th World Cup

Long after Mexico’s World Cup win against South Korea, fans young and old lined up outside the stadium to take photos with Héctor Chávez and his big black sombrero. Also known as Caramelo, candy in English, Chávez is arguably as well-known in Mexico as the members of the national team. Now at his 11the World Cup, Chávez is flanked by his 21-year-old son, also called Héctor Chávez, and known as Caramelo Jr. Both wear oversized sombreros with their nicknames written in all caps, making them hard to miss at stadiums.

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Jun 23 • 4:58 PM EDT • Sports • sports.yahoo.com
NCAA Division I Cabinet OK's 5-year, age-based eligibility

The NCAA Division I Cabinet unanimously approved a new five-year, age-based eligibility model. This marks a win for the NCAA, as it attempts to bring consistency to the landscape.

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Jun 23 • 3:25 PM EDT • Sports • espn.com
KC promised a World Cup economic boost. But not for every business, leaders say

As some businesses question the World Cup’s effect on the Kansas City economy, local officials and event organizers say they still expect a boost for the city.

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Jun 23 • 3:12 PM EDT • Business • kansascity.com
Warton grad who used to pressure wash homes raises $40M to help plumbers, electricians run businesses with AI

George Eliadis, 24, raised venture capital funds from Andreessen Horowitz and Sequoia Capital for Probook, his AI platform for home service businesses.

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Jun 23 • 3:06 PM EDT • Business • foxbusiness.com
Wharton grad who used to pressure wash homes raises $40M to help plumbers, electricians run businesses with AI

George Eliadis, 24, raised venture capital funds from Andreessen Horowitz and Sequoia Capital for Probook, his AI platform for home service businesses.

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Jun 23 • 3:06 PM EDT • Business • foxbusiness.com
A South Kansas City bar and restaurant will close after 5 years in business

Specials will be announced throughout the week.

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Jun 23 • 2:33 PM EDT • Business • kansascity.com
NCAA votes to approve age-based five-year eligibility rule, reshaping college football, basketball landscapes

Under the new rules, all college athletes will have five years to play five seasons

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Jun 23 • 2:29 PM EDT • Sports • cbssports.com
NASA satellite captures wave of warm water hundreds of miles long that signals a devastatingly strong El Niño

This year's El Niño is on track to be among the strongest ever recorded.

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Jun 23 • 1:53 PM EDT • Science • livescience.com
TIME Launches The CEO Moment with Sam Jacobs, Expanding Its Coverage of Business Leadership with a New Video Interview Series

TIME launched The CEO Moment with Sam Jacobs, a new monthly video interview series hosted by TIME's Editor in Chief that expands TIME's coverage of business leadership through in-depth conversations with the executives shaping today's business landscape.

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Jun 23 • 12:38 PM EDT • Business • time.com