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Scientists find a bone-building switch that could fight osteoporosis
An experimental compound called AP503 significantly strengthened bones in mice by activating GPR133, a receptor that boosts bone formation while slowing bone loss. Because the same treatment has also been linked to stronger muscles, researchers see intriguing potential for combating age-related decline and osteoporosis.
Montreal-Based Proteus Labs Partners with Avantis Education to Bring Immersive Virtual Science Labs to Classrooms Worldwide
Proteus Labs, a Montreal-based developer of immersive mixed reality science lab applications for K–12 education, today announced that its unique mixed reality science lab application has been selected to be part of Avantis Education's ClassVR Xcelerate headset and new EduverseSTEM platform, extending hands-on virtual science experiments to schools in 90 countries.
As science comes under attack at UN talks, climate movement splits over how to respond
A rift over how IPCC messages are produced and turned into policy is creating tensions in the world's most influential coalition of climate NGOs
Scientists in Switzerland made a sponge from cheesemaking waste that captures gold from discarded electronics — after dissolving metal parts from 20 old computer motherboards, they recovered enough to melt into a 22-carat gold nugget
A Swiss lab transformed dairy waste into a gold-recovery tool, extracting precious metal from e-waste that most recyclers leave behind.
Recent Stanton graduate wins Humane Science Award from National Anti-Vivisection Society
/PRNewswire/ -- Alan Alwakeel, a recent graduate of Stanton College Preparatory School in Jacksonville, Florida, was one of just five recipients of the...
Recent Stanton graduate wins Humane Science Award from National Anti-Vivisection Society
Alan Alwakeel, a recent graduate of Stanton College Preparatory School in Jacksonville, Florida, was one of just five recipients of the prestigious Humane Science Award at the 2026 Regeneron International Science and Engineering Fair (ISEF). The award is presented by the National Anti-Vivisection Society (NAVS), a nonprofit devoted to the advancement of science without harming animals and the only animal advocacy group invited to award a prize at the ISEF. Each recipient received a $3,000 prize
Zhongzhong Science & Tech Tianjin's Shareholders To Unload Stake
Zhongzhong Science & Technology Tianjin Co Ltd SSE:603135:
14 of Science’s Biggest Mysteries We’re Still Trying to Figure Out
There’s a lot we know today that humanity didn’t know hundreds of years ago, and there will likely be a lot people will learn in the coming years that we can’t possibly know right now. Among these que...
Guelph meat science faculty went from five to zero
Federal funding flowed to Protein Industries Canada and plant proteins after 2018 while a $32-billion meat industry went without its share.
Mayoral candidates must improve public engagement; Prop 134’s flawed science (Letters)
Currently, there is little effort by the City of Boulder to bring opposing groups together to seek common ground. Public input is only solicited after a department has made a decision, so that “engagement” feels like a sales pitch. Boa…
The science of friendship and loneliness
Assistant professor of psychology Jessica Ayers’s new research challenges assumptions about the kind of friendships we need
Gilead opens new research centre bringing together oncology, inflammation and research data science teams
The centre in California supports the company’s $32bn US investment
Slime mould has no brain, no neurons and no central control, yet when scientists placed food at 36 locations matching cities around Tokyo, it grew a network strikingly similar to the rail system — with comparable efficiency, cost and resilience
A single-celled organism with no brain solved a transportation puzzle that took human engineers decades to perfect.
Film and TV Portrayals of A.I. Go Beyond Science Fiction
Plots involving some kind of artificial intelligence are even part of soap operas. Here’s how they’ve evolved over the decades.
NOAA Fisheries Takes A ‘Sharp Turn Away From Science’
The agency’s focus on commercial interests threatens fisheries science and over one million miles of protected marine habitats.
A little stardust, a little magic: Hyla senior takes science to the stage
There are plenty of reasons to spend a Saturday night looking up. On Sept. 12, Bainbridge Island has another one: a local high school senior who thinks quantum mechanics might go down a little easier with a dose of magic.
Tiandi Science & Technology's Shareholder Plans To Raise Holding
Tiandi Science & Technology Co Ltd SSE:600582:($1 = 6.7075 Chinese yuan renminbi)
China-Nepal floods; ‘Asian water tower’ wobbling: 7 science highlights
From Beijing’s bid to stop US AI dominance to impact of China-Nepal floods, here are some highlights from SCMP’s recent science reporting.
Slime Molds and a double Ig Nobel Prize winner and a big, great science adventure
” ‘This is dangerous’: slime moulds and the bitter debate over the nature of intelligence — Scientists are battling over whether supposedly simple organisms should be considered ‘intelligent’…
The five deep-sea arrays of the Ocean Observatories Initiative had been streaming continuous readings from the Atlantic and Pacific since 2016, and in May 2026 the National Science Foundation said four would be pulled out of the water before reversing course on June 18
The five deep-sea arrays of the Ocean Observatories Initiative streamed continuous readings from the Atlantic and Pacific for a decade. In May 2026 the National Science Foundation moved to pull four of them out. A bipartisan Senate revolt reversed the plan — but the data gap and the deeper funding cliff remain.
Can Innovative Fabric Science Solve the Workplace Safety Crisis? "All Access hosted by Andy Garcia" Explores Breakthroughs with Portwest
/PRNewswire/ -- Filmed on August 25, 2026, a new segment of "All Access hosted by Andy Garcia" highlights how modern material science is tackling...
Non-nutritive sweeteners may aid sugar reduction without affecting weight or health
The review, led by Eva Marija Čad of the University of Ljubljana and Wageningen University & Research, alongside Professor Graham Finlayson of the University of Leeds and colleagues from other institutions in the Netherlands, Denmark, Spain and Belgium, was developed in connection with a 2025 webinar series hosted by the Institute for the Advancement of Food and Nutrition Sciences (IAFNS).
Curiosity Blog, Sols 4995-5001: 5,000 (Martian) Days on Mars
Written by William Farrand, Senior Research Scientist, Space Science Institute
Signs of US-style polarisation in Britons’ trust in science
Sense of shared identity makes Greens’ faith in scientists stronger than Reform voters’, study finds
America’s New National Security Science & Technology Strategy
America’s New National Security Science & Technology Strategy Should Test Authority, Not Just Capability The White House is right to make AI, autonomy, resilient PNT, advanced sensing, cyber
America’s New National Security Science & Technology Strategy
America’s New National Security Science & Technology Strategy Should Test Authority, Not Just Capability
Legislators receive science education center proposal
Legislators on the Interim Joint Committee on Education recently expressed interest about boosting Kentucky’s science education while hearing a proposal for the creation of the Kentucky Center for Science Education.
A Marine Science Michelangelo?
Angelique Allen merges ocean art and octopus neuroscience at Santa Barbara Sea Glass & Ocean Arts Festival.
Study Findings Conflict with Body of Science Linking Pesticides to Attention Deficits and Autism - Beyond Pesticides Daily News Blog
A recent study finds no connection between levels of urinary biomarkers of organophosphates and autism-related traits, conflicting with a wide body of research.
Anak Krakatau Rumbles Again
A powerful eruption from the Indonesian volcano lofted ash into the atmosphere, disrupting thousands of flights and degrading air quality.
Cleveland Clinic, RIKEN and IBM Team Advance to Finals for 2026 ACM Gordon Bell Prize
Joint research team modeled a 12,635-atom protein, the largest-known to be simulated using quantum computers. Breakthrough was achieved through quantum and classical methods working together, expanding quantum-centric supercomputing’s potential in life sciences research.
US Research Cuts Drive Scientists to Germany
US-based researchers are seeking academic asylum in Germany following the Trump administration’s funding cuts—a loss to American science.
The public's trust in science and medicine
A recent survey of the public about their trust in science and medicine was reassuring: scientists and physicians are well-respected. But it also raised some concerns. The 2026 Edelman Trust
Mack Cleveland: Using computational materials science to engineer higher burnup fuels
Propelled by a love of mathematics and materials science, the MIT doctoral student models granular chemical reactions in uranium dioxide, work that might lead to less fissile nuclear waste and improved plant performance.
NASA X-59 explainer: Science of sonic booms
The most common misconception about sonic booms is that they’re just the sound created at the moment when an aircraft “breaks the sound barrier.”
Archimedes Science Award 2026
Detlef Günther, Swiss Federal Institute of Technology (ETH) Zurich, Switzerland, honored
A (temporary) win for science and sanity
Congress rejects rule that would give Trump control over all research and academic grants—for now
Scientists Had People Eat Tomato Paste For 3 Months. Their Brain Scans Looked Different.
It contains a powerful antioxidant.
A beginner’s guide to open science
Open science may seem impenetrable for early career researchers. Sarahanne Field explains what it is and how to get started
Have we found alien life? Hundreds of scientists weigh in
Two major alien-life announcements in 2025 generated enormous excitement, but most astrobiologists remained unconvinced. Only 6.6% of surveyed experts thought possible biological molecules on K2-18b probably represented extraterrestrial life, while 15.1% said the same about intriguing mineral patterns in a Martian rock.
“Parachute science” is failing the tropics, home to more than 80% of insect species
Insects quietly hold much of the natural world together, yet conservation efforts are overlooking the tropical regions where more than 80 percent of insect species live. Monash University researchers have developed a global framework to close this gap by combining scientific studies with museum collections, local expertise, citizen science, social media records, and new technologies.
Chinese scientists find a hidden atomic structure that unlocks methane
Scientists found that a tiny atomic structure that forms on nickel oxide during methane conversion is more effective than the metallic nickel long believed to drive the reaction. The discovery allowed a low-nickel catalyst to rival one containing 10 times more metal, potentially opening the door to cheaper and more efficient industrial catalysts.
What Will Life Science Orgs Do When The AI Bill Comes Through?
AI is transforming clinical development, but what happens when usage costs spike? Jon Newton explains how to govern it before the bill lands.
Geologists reveal the Americas collided millions of years earlier than thought
Volcanic rocks in Colombia are rewriting the timeline of the collision between Central and South America. Their magnetic signatures show that major tectonic deformation had already weakened by the late Miocene, suggesting the most intense collision occurred earlier than previously believed.
The Nonlinear Science Behind Large Language Models
LLMs are black boxes, but the principles that govern them are not. Read this article for a detailed introduction to chaos and complexity theory applied to LLMs.
Why General AI Coding Assistants Fall Short in Science
Generic AI coding assistants struggle with scientific workflows. Rolv v3 adds reproducibility, biomedical intelligence, HPC execution, and visual DAGs.
Helping Children Unlock the Science of Reading
For children who struggle to read, even a single page can feel like a puzzle everyone else already knows how to solve. Certified reading specialist and author Christie Welsby is helping families na…
Hundreds protest plans to close Philly's Academy of Natural Sciences: "We're going to make our voices heard"
The trail of clues that our planet might be heating faster than we realised
A curious online row over this summer's heatwaves points to a wider - and worrying - shift in climate science.
The trail of clues that our planet might be heating faster than we realised
A curious online row over this summer's heatwaves points to a wider - and worrying - shift in climate science.
Ohio cannabis store voluntarily closes as state investigates ‘serious health events’
Arizona-based Vext Science said late last week it had voluntarily shuttered a cannabis store in Jackson, Ohio amid a health investigation.
The science of sleep trackers on smart watches
In this segment, scientists are issuing a caution about sleep trackers featured on devices like Apple Watch.
Glendale Actress Finds Love of Science
A few years ago, Marilyn Heidecker was more likely to portray a criminalist on TV, film, or stage rather than work as an actual scientist who analyzes physical evidence in
STEAM Minute | The science behind developing and restoring film
While digital photography is the most common way to take pictures now, many people still use film photography for its unique look and nostalgic feel.
From Backyard Ziplines to Self-Driving Cars: UCLA Computer Science Student Develops Tools to Help Autonomous Vehicles Safely Share Information
One of the fondest childhood memories of Alexandra Markova was a weekend spent running around Home Depot with her father and three siblings.
Protesters rally against Academy of Natural Sciences closure
Protesters rallied outside the Academy of Natural Sciences Tuesday as the 198-year-old Philly museum prepares to close at the end of September.
Unlocking Forest Diversity from Above: Fieldwork at Smithsonian’s BiodiversiTREE
Laying groundwork for using airborne remote sensing to better understand the characteristics of forest species diversity.
3 Takeaways From the Latest PISA Test of Reading, Math, and Science
The results show reading performance dropping across the world—and one uniquely troubling U.S. trend.
UNC Charlotte's Truman Lab awarded new $2.1 million grant from the National Institutes of Health
UNC Charlotte’s Truman Lab has secured a new $2.1 million grant from the National Institutes of Health to advance fundamental research on how cells maintain protein health, a process central to diseases ranging from cancer to neurodegenerative disorders. The five-year Maximizing Investigators’ Research Award from the National Institute of General Medical Sciences will support the […]
UNC Charlotte's Truman Lab awarded new $2.1 million grant from the National Institutes of Health
UNC Charlotte’s Truman Lab has secured a new $2.1 million grant from the National Institutes of Health to advance fundamental research on how cells maintain protein health, a process central to diseases ranging from cancer to neurodegenerative disorders. The five-year Maximizing Investigators’ Research Award from the National Institute of General Medical Sciences will support the […]
Southern Union names Pike dean of health sciences
CONTRIBUTED BY SUSCC OPELIKA — Southern Union State Community College has named Dr. Richard Pike as dean of health sciences. Pike assumed the position Sept. 1 following the retirement of Dean Rhonda Davis. A graduate of Southern Union, Pike earned an associate in science degree and his emergency medical technician certification from the college. He […]
Joint Observations with Swift removed from IXPE GO Cycle 4
The IXPE Guest Observer (GO) Program solicits proposals for investigations in any area of astrophysics (not constrained to IXPE’s prime science areas).
Pittsburgh entrepreneur donates storage systems to Seton Hill business, technology school
The founder of a Pittsburgh-based digital storage solutions company donated $35,000 worth of equipment to Seton Hill’s cybersecurity and computer science programs. Gene Leyzarovich, former Jetstor CEO, founded the Bloomfield company more than 30 years ago while studying at the University of Pittsburgh and working night shifts at UPMC. The
Celo to Participate in Merkle Science Meet in Washington, D.C. on September 8th
Celo will participate in Merkle Science Meet in Washington, D.C. on September 8th at 18:00 UTC. Markus will join a panel on the GENIUS Act and the future of U.S. stablecoin regulation.Refer to the official tweet by CELO:Kicking off @thestablecon week today, @MarkusMento speaks at @MerkleScience Mee…
Congratulations to Our New CRUK Funded Researchers - Cancer Research UK Science and Innovation
Congratulations to Our New CRUK Funded Researchers - Cancer Research UK Science and Innovation / Amy Case, Andy Scarsbrook, cancer, Cancer Research UK Science
Moment of Science: Abundant oxygen not enough to explain massive ancient insects, new study suggests
Unlocking answers about giant ancient insects! Here's why an abundance of oxygen 300 million years ago may not explain why some animals got so gigantic after all.
At rally to save Academy of Natural Sciences museum, protesters urge Drexel to 'act like it's an emergency'
Local lawmakers and scientists outlined several options to preserve the museum, which is due to close Sept. 30.
An AI Formalized and Verified Fermat’s Last Theorem in 11 Days, a Task Expected to Take Years
Claude did not rediscover the proof. It made the existing one machine-checkable.
Scientists Keep Finding the Same Mysterious Beat Across the Animal Kingdom, From Fireflies to Sea Lions
From fireflies to mammals, evolution may have tuned communication to the rhythm of neurons.
Scientists Discover Bacteria That Can Make Testosterone Near the Prostate, With Potential Implications for Cancer
A newly discovered bacterial pathway turns a common steroid precursor into testosterone.
OECD: Heavy AI Use Linked to Lower Science Scores
New PISA data shows students who use AI daily score 28 points lower in science; OECD urges using AI to support, not replace, learning.
Meet Rachel Chen, the 18-year-old Los Angeles student who expanded a 1997 quantum-math idea to describe entire particle systems with simple diagrams; she won $100,000
At just 18, Rachel Chen has taken a decades-old mathematical idea and expanded it into a visual framework for understanding complex quantum systems, earning her a $100,000 award in the 2026 Regeneron Science Talent Search.
From science to screen time: 4 key takeaways from the latest PISA results
Amid reading declines that included a 14-point drop for the U.S., researchers are looking at the role digital learning and AI may have played.
Stand Up for Science Demands Congress Stop Transfer of National Institutes of Health Research Funds to
New petition urges Congress to stop an interagency agreement that would allow health research money to fund War Department’s unspecified priorities.
Stand Up for Science Demands Congress Stop Transfer of National Institutes of Health Research Funds to
New petition urges Congress to stop an interagency agreement that would allow health research money to fund War Department’s unspecified priorities.
Hundreds rally to protest the planned closure of the Academy of Natural Sciences museum
The crowd was decidedly intergenerational.
OpenAI Says It Has Cracked One of Math’s ‘Millennium Problems’
The company’s announcement is the most dramatic sign yet that artificial intelligence is fundamentally transforming the field of higher mathematics.
Bentley Awarded $235,000 to Strengthen Life Sciences Talent Pipeline
Bentley University will use $235,000 grant to prepare students for business roles in life sciences to meet Massachusetts workforce need.
From California to the Moon: Daniel Rivers and Sally Ashton Explore the Intersections of Art and Science NewsCenter | SJSU
Two new books from San José State faculty take on that question through explorations of environmental justice, space, California history and the possibilities of more just futures.
Rally held to keep Philadelphia's Academy of Natural Sciences museum open
Protesters held a rally Tuesday calling for officials to save the Academy of of Natural Sciences museum in Center City Philadelphia.
Science center adds laser-light showings in Dome
Musical presentations available on a la carte basis on select evenings
Are rich people really worse behaved? Here’s the science
Who’s more likely to steal sweets from a child? According to science, it’s the rich. A study seemingly confirming our suspicions about the moral behaviour of the wealthy was one of the winners of the 2026 Ig Nobel prizes, which honour research that makes you laugh and then think. Science editor Ian Sample tells Madeleine Finlay what the researchers think could be behind the phenomenon, and they explore some of the other awards, including one for a surprising quality we look for in our friends and another for a biomechanical definition of kissing
Kansas City psychiatrist explores the science behind high emotional sensitivity
Dr. Sasha Hamdani's new book, "Too Sensitive," aims to provide a science-backed, empathetic framework for understanding why some people experience high emotional sensitivity. The Kansas City psychiatrist joined KCUR's Up To Date on Tuesday.
How Can Behavioral Science Help Increase HPV Vaccination Uptake? - ACS Global
How Can Behavioral Science Help Increase HPV Vaccination Uptake? - ACS Global / ACS Global, Ali Maryam Jamila, American Cancer Society, cancer, CCAE, Cervical
How UC Davis Strengthens the Forensic Science Workforce
Meet UC Davis students and alumni using a forensic science degree to build careers analyzing DNA evidence and chemicals in crime labs.
Humann Names Dr. Harold Schmitz Science Advisory Chair and Announces Nutrition Research Partnership with the UC Davis Innovation Institute for Food & Health
/PRNewswire/ -- Humann, the Austin-based cardiovascular health supplement company, continued its legacy of engaging with leading academic institutions by...
New-to-science Amazon frog stands out for its slow ‘lazy’ song
Scientists recently described a new species of a tiny brown frog found in the Amazonian floodplain forests of Ecuador and northwestern Brazil. It looks nearly identical to related species but its slow, widely spaced out call sets it apart, researchers note in a study. “I’ve had to get into arguments because people said the frog […]
Global report shows where US kids rank in reading, math and science
ABC News' Elizabeth Schulze has the results of a new report released this morning showing where U.S. students rank compared with students around the world.
Moment of Science: Abundant oxygen not enough to explain massive ancient insects, new study suggests
Unlocking answers about giant ancient insects! Here's why an abundance of oxygen 300 million years ago may not explain why some animals got so gigantic after all.
Penn State Dairy Barns Made Animal Science Student ‘Feel at Home'
UNIVERSITY PARK, Pa. — Three years of working in Penn State’s Dairy Barns have been impactful for Hannah Mansfield, a spring 2026 College of Agricultural Sciences graduate who is...
‘Science at the Fifty-Third Degree’ humanizes research advancements through conversation
Episodes highlight the collaborative nature of science, and expand accessibility of discoveries happening at the university.
Kamin Science Center and Science of Speed shut down for four-day refresh in Pittsburgh
Planning a trip to the Kamin Science Center this week? The museum will be closed through Friday for exhibit maintenance and updates.
AZ's R&D chief Barr touts internal 'science success story' after IL-33 antibody's stellar showing in COPD
With a detailed data drop that AstraZeneca’s R&D chief described as an internal “science success story,” the British Big Pharma has secured an FDA priority review for what it believes could become a flagship biologic in chronic obstructive pulmonary disease (COPD). In detailed results from the late-stage Oberon and Titania trials—first teased in March and detailed in full at the European Respiratory Society Congress in Barcelona this week—the drugmaker laid out the extent of its IL-33 inhibitor’s potential to reduce moderate and severe exacerbations in a wide range of COPD patients still struggling with those “lung attacks,” as AstraZeneca’s Sharon Barr, Ph.D., called them, despite using standard-care inhaled therapy. In the headline results, a 300 mg dose of tozorakimab given once every four weeks curbed those moderate and severe exacerbations in the studies’ primary population of former smokers by 29% in the Oberon study and 34% in Titania. In the overall population of both current and former smokers, these reductions were 30% and 29%, respectively, versus placebo and inhaled standard of care. The benefits also extended to clinically meaningful exacerbation reductions in all prespecified patient subgroups and specifically turned up promising signals in patients across a range of blood eosinophil counts, with Barr telling Fierce that “it’s the details that make this even more exciting than the high-level results that we’ve already shared.” In fact, during AZ’s tozorakimab poster presentation at the ERS 2026 Congress this past weekend, attendees were so enamored by the data that event organizers had to encourage people to clear the room and look at the other presentations on offer, Barr said in an interview. “I think it really speaks to the fact that there is a lot of buzz around these data because the entire respiratory community has been so desperate for new therapies for these patients,” she explained. The respiratory disease continues to represent a “staggering unmet medical need,” Barr said, highlighting the COPD exacerbations that the Oberon and Titania studies homed in on, which she added carry a greater mortality risk than a heart attack. “When a patient has a severe exacerbation, only about half of them are still alive within three and a half years,” she pointed out. As for tozorakimab specifically, Barr christened the molecule “an AstraZeneca science success story,” harkening several years back to the point at which researchers began to explore IL-33 as a driver of respiratory disease, and COPD in particular. At the same time, “there was still so much that wasn’t understood,” she admitted, highlighting the insight that IL-33 signals through both ST2 and EGFR through the RAGE pathway, a discovery Barr attributed to AstraZeneca's own scientists. Understanding the need to tackle both pathways in COPD—and aware of competitor candidates in the hopper, including one that bound ST2—the company ultimately had to make some “courageous decisions,” Barr said. These included taking a prior COPD molecule offline and going back to the drawing board to reinvent its potential IL-33 label “to make sure that we had a molecule that could block signaling through both arms of the pathway, through both the reduced form and the oxidized form, knowing that we wouldn’t be first, but striving to be best.” “When we put [tozorakimab] into the clinic, we firmly believed that we had a differentiated molecule, and we saw the other molecules blocking just ST2 or partially blocking IL-33, unable to deliver two positive pivotal studies in COPD,” Barr explained. “We kept marching forward because we believed our molecule was differentiated, and now I think we have the clinical validation that supports that.” Ultimately, AstraZeneca finds itself on much better footing these days when it comes to potential biologic rivals to tozorakimab in COPD. Sanofi and Regeneron’s Dupixent, for instance, is approved to treat COPD exacerbations in patients with high eosinophil counts, but not low ones. Meanwhile, the future has become cloudier for other next-gen IL-33 candidates from Sanofi and Regeneron, as well as Roche, which have suffered trial flops in recent years. One other potential ingredient for AstraZeneca’s success in its duo of studies was that the company was “ambitious in the trial design, willing to look at an all-comers population,” Barr said, “and willing to enroll the most severe patients.” Prior studies for would-be biologics rivals in COPD “avoided enrolling” those patients, she pointed out. She also highlighted the Big Pharma’s painstaking design of exacerbations in its trial, which “gave us a very rigorous readout,” and pointed to “the extra effort and investment” the company put in to understand the effect of mucus plugs in patients. Barr described mucus production as a “key feature in disease diversity,” noting that mucus plugs—obstructing clumps of mucus that block patients’ airways—are associated with worse outcomes in COPD. In its data announcement, AstraZeneca noted that an integrated analysis of Oberon and Titania found tozorakimab “demonstrated a reduction in patients’ mucus plug score,” with the pharma claiming its biologic is the first to deliver such results in a broad COPD population. “So being able to reduce those mucus plugs, we expect, is an important part of driving benefit for patients who are living with COPD,” Barr said. Again touching on the breadth of the study populations, Barr added that tozorakimab “worked across all eosinophil levels in both current and former smokers across all levels of lung function,” which she suggested “really simplifies decision-making for clinicians, and it allows them to offer therapy to the broadest possible patient population.” In the highest patient eosinophil count group, tozorakimab helped chart a 43% reduction in exacerbation risk, which Barr stressed were “unprecedented data.” In the mid-level group, AZ’s drug delivered a 23% reduction and, in the lowest group, a 34% reduction in eosinophils, which Barr said suggests efficacy “in all patient subgroups.” As for AZ’s recent guidance upgrade on the medicine’s sales opportunity, the lift from a $3 billion to $5 billion range to $5 billion plus was informed by multiple factors, Barr said, including the fact that “in 2024, there were multiple competitors, and there aren’t anymore.” Additionally, “we know that this is a massive unmet medical need, and this is a really incredible set of data that we think will be very convincing to the clinical community,” Barr said. Looking ahead to a potential evolution of the COPD treatment landscape, Barr noted that most patients start treatment in the community with an option like a triple therapy, and for them, having an option like AstraZeneca’s inhaler Breztri will remain a “really important part” of that journey. But of the patients uncontrolled on triple therapy, which Barr described as “about half of them today,” just a “small fraction” are currently eligible for biologic therapy, which she emphasized AstraZeneca is working to change. Understanding that COPD is not a “one-size-fits-all” disease, AstraZeneca is also looking at its antibody drug Tezspire for patients with T2-driven disease, and the company continues to think about new mechanisms for tackling COPD through both systemic and inhaled drugs, Barr said.
UC Berkeley Law event targets Trump science policies as ‘censorship’
The University of California, Berkeley School of Law organized an Aug. 25 discussion focused on resisting censorship and protecting academic freedom in scientific research.
Hong Kong students drop in global rankings for maths, science and literacy
City’s students drop out of global 10 in Pisa’s science section – the first time since Hong Kong joined international assessment.
NASA Sea Level Science Makes Waves on World Ocean Day
Explore This SectionScienceScience Activation1,000 Museum Visitors Dive… OverviewResourcesOpportunitiesCitizen ScienceHighlightsAbout Science
SC's Emerging Biotech Industry Receives National Recognition
Genetic Engineering & Biotechnology News (GEN) recently named the Palmetto State among its “Regional and State Clusters to Watch” in its first-ever Next 10 U.S. Biopharma Clusters report, highlighting emerging life sciences ecosystems beyond...