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Bills player dismisses Patriots hero as ‘practice squad player’
After a 0-3 start to the season, the New England Patriots were able to bounce back in a big way on Sunday afternoon, pulling off an upset win over the Buffalo Bills on the road after Patriots wide receiver Efton Chism III made a ridiculous catch to give the Patriots the lead with under two…
Roundtable Ravens Episode 42 - Breaking Down Week 4 Win
Roundtable Ravens crew James Brizuela and Billie Melissa break down the Baltimore Ravens' Week 4 win against the Tennessee Titans.
Gypsy Rose Blanchard addresses 'significant tension' with Ken Urker's sister
Gypsy Rose Blanchard is responding to criticism from Ken Urker's sister following the death of Urker, the father of her daughter.
Trump won this district by 10 points. This Democrat thinks he can win it by winning back Latinos
WindRose Health Network Discloses Data Breach Affecting 33K Individuals
Data breaches have been announced by WindRose Health Network and Advantage Home Health Care in Indiana, Camden-on-Gauley Medical Center in West Virginia, WindRose Health Network in Indiana has reported a data breach affecting more than 33,000 individuals. Data breaches have also been reported by Advantage Home Health Care in Indiana, Camden-on-Gauley Medical Center in West Virginia, and Lakes Region Visiting Nursing Association in New Hampshire.
Greenfield Business Association distributes inaugural Buzz Awards
Greenfield Business Association held its first Buzz Awards at Four Phantoms Brewing Co., celebrating local shops like Hope & Olive and Freedom Cafe.
Windows 11 26H2 isn’t exciting, but it does fix one real problem
Windows 11 26H2 doesn't bring much new, but it cuts RAM usage by up to 2GB on some PCs and makes older PCs run smoother.
Google Wallet for Android adds 12th digital state ID
Following the last launch at the end of August, Google Wallet is rolling out support for Oklahoma state IDs on Android.
God Packs are Officially Coming to Magic: The Gathering
Magic: The Gathering booster packs have gone through a lot of changes in the last decade, some of which have been awful. But Wizards of the Coast are introducing 'God Packs' to MTG, which could feel like winning the lottery.
Banijay Entertainment Unites US Operations With Banijay America Following All3Media Merger
Ben Samek will serve as the CEO of this division, which will now house Turnkey Studio Services
Banijay Entertainment Unites US Operations With Banijay America Following All3Media Merger
Ben Samek will serve as the CEO of this division, which will now house Turnkey Studio Services
49ers’ Mike Evans Reveals Truth About Playing Through Rib Injury
Mike Evans was not expected to play this week. He suited up anyway. The San Francisco 49ers receiver played through a painful rib injury in a 24-14 win over the Denver Broncos. Evans Beats the Odds for the 49ers Evans hurt his ribs in Week 3 against the Arizona Cardinals. Many assumed he would miss […] The post 49ers’ Mike Evans Reveals Truth About Playing Through Rib Injury appeared first on HEAVY.
Trump is clearly trying to buy votes with taxpayer money
President Donald Trump is ramping up his efforts to use taxpayer money and resources to help Republicans win the 2026 midterm elections.
FSU's Mike Norvell earns major honor amid growing scrutiny
After a week of mounting pressure surrounding his future at Florida State, Mike Norvell earned CBS Sports' ACC coach of the week recognition.
Justin Bibb’s new Blue Cities/Red States coalition seeks the ‘radical center’
Cleveland Mayor Justin Bibb is launching Blue Cities/Red States, a 15-mayor coalition aimed at showing Democrats can govern effectively even when Republicans control their statehouses.
Alex Ovechkin Retiring at End of Season
Alex Ovechkin announced the 2026-27 season will be his last, including one final trip to Detroit. #RedWings
Mystery Hill launches first after dark experience
BLOWING ROCK — Mystery Hill, home of North Carolina’s only Natural Gravitational Anomaly, will remain open after sunset this fall for Mystery Hill After Dark, a new evening event series
Fan Notes from the Patriots’ win over the Bills
Notes, musings, and observations from New England’s win over the Bills.
Concerns About Tinubu’s Health
As the next presidential election looms, anxiety about the Nigerian president’s physical condition is growing.
Concerns About Tinubu’s Health
As the next presidential election looms, anxiety about the Nigerian president’s physical condition is growing.
Stock up/stock down for Kentucky after beating South Carolina
The Kentucky football team got a comeback win over South Carolina this week. Here's whose stock is soaring, and whose isn't afterwards.
Inter keen on Cagliari rising star Alessandro Romano
Inter show no inentions in slowing down their recruitments following a very active summer market as the Nerazzurri are keen on acquiring the services of Cagliari and Azzurri rising star Alessandro Rom...
‘Primetime’: Is catching predators justice or just entertainment?
Rating: ★★★½ Starring Robert Pattinson, Skyler Gisondo, Merritt Wever Directed by Lance Oppenheim Rated R Release Date: Sept. 25, 2026 A man waits unknowingly inside a sting house. His eyes draw up to the sound of curtains ruffling as Chris Hansen (Robert Pattinson), host of Dateline NBC’s “To Catch a Predator,” enters flamboyantly. Hansen descends...
RYOBI Cleans Up Local Politics with Unlikely Mayoral Candidate 'Swifty'
McCann Birmingham and RYOBI unveil the first trailer for a documentary following the spot cleaner’s unlikely bid to become mayor of Staines
Silly Dillys Wins $30,000 at RISE Up Harlingen Business Pitch Competition
Silly Dillys captured first place and a $30,000 award at the third annual RISE Up Harlingen Business Pitch Competition, leading a group of local entrepreneurs receiving financial support to develop and expand their businesses.
Juventus Following Dutch Duo Ahead of Next Summer
Two high-ranking Juventus officials attended the recent Nations League game between Germany and the Netherlands to keep tabs on Brian Brobbey and Virgil van Dijk. The pair is on their radar ahead of n...
58,000 Hoosiers not in compliance with new HIP work rules
The Indiana Family and Social Services Administration shared internal estimates Monday showing 58,000 Hoosiers insured through the Healthy Indiana Plan are not in compliance with federal work requirements set to take effect next year.
Ninja Theory developers announce they are facing redundancy, as the studio starts laying off staff following widespread Xbox cuts
Ninja Theory staff on LinkedIn have shared either farewell messages or sombre posts on the ongoing redundancy process happening at Ninja Theory.
USA TODAY Sports Super 15 East region football rankings, Week 8
Here are the latest USA TODAY Sports East Region rankings following a wild week of high school football action.
Can Democrats expand their Senate map?
Plus: Will Ken Paxton's estranged wife help him win?
Senua At Risk Of Cancellation As Ninja Theory Employees Announce They've Left The Studio
"It’s incredibly sad knowing that we won’t get to finish..."
Sphere Entertainment (NYSE:SPHR) Shares Gap Down Following Analyst Downgrade
Sphere Entertainment (NYSE:SPHR) Shares Gap Down Following Analyst Downgrade
Windows 11 26H2 brings a hidden performance boost — and may slash RAM usage
Windows 11 26H2 quietly brings several performance improvements, including a Low Latency Profile that makes common tasks feel faster. Some users are also reporting lower RAM usage after the update, although Microsoft has not confirmed that 26H2 itself is responsible.
Beazley and Zurich Global Specialty Names New CEO
Kristof Terryn has been appointed as chief executive of Beazley and Zurich Global Specialty following Switzerland-based Zurich Insurance Group AG’s acquisition of British firm Beazley plc…
Collective Ethics in an Autocratic Climate: M. Gessen Discusses the “Politics of the Past and Politics of the Future”
What are our ethical obligations as students living, learning, and creating a politics of the future at Haverford College? We must establish a clear set of ethical principles that we are unwilling …
Science Corp. Announces Long-Term (36 Months) Results of PRIMA BCI Clinical Trial Showing Durable Vision Restoration in Blind Patients Suffering from Geographic Atrophy
Science Corporation, the neural engineering and brain-computer interface (BCI) company, today announced long-term (36 months) followup data from its pivotal ...
Spurs' Harris questionable for regular-season opener after straining left calf
The 6-foot-8 power forward will be reevaluated following the team’s five-game preseason schedule.
Should Aging Be Called a Disease? Scientists Are Rethinking What It Means to Grow Older
What if the next big target in medicine is getting older itself? Researchers are taking that possibility seriously, with new tools, new clinics, and growing FDA attention. Instead of waiting for diabe...
What we learned from Wales' Nations League window
On the back of a demanding four-game international window, BBC Sport Wales assesses the key talking points from Wales' Nations League A campaign so far.
Syracuse Football: How Do Oddsmakers Feel About Matchup with Virginia?
The Orange are back in action this weekend against the Cavaliers following a 42-41 win over UConn.
Top Workplaces 2026: LJA Engineering takes top spot for large businesses
Empowering employee growth through a stock ownership plan, LJA Engineering is the Orlando Sentinel’s 2026 Top Workplaces in Central Florida winner in the large business category.
Windows malware uses Grok AI to help stay hidden, researchers say
x47.c Windows malware uses xAI's Grok to maintain persistence on infected PCs while stealing passwords, browser cookies and API keys from victims.
CeeDee Lamb’s late TD caps a wild Cowboys rally to beat winless Texans 34-30
The Cowboys star receiver had a career day in Houston.
First Glance: Missouri Tigers
Aggies seeking a statement win to get the season back on track
2026 Outstanding Women in Business
The 18th annual Outstanding Women in Business awards recognize a dozen well-accomplished professionals from across the region and in many industries who go above and beyond. The committee selected the winners from more than 80 nominations, all of whom were worthy. The criteria evaluated each nominee’s professional achievements, community impact, ability to break the glass ceiling and mentorship of other professionals, particularly women. In addition to profiling these women in the following pages, the Worcester Business Journal will celebrate this year’s Outstanding Women in Business at a special luncheon on Oct. 28 at the College of the Holy Cross. To join the celebration of these exceptional women, visit WBJournal.com and register. – Mark Conti, editor This Year’s Judges Worcester Business Journal considered 54 Central Massachusetts professionals for the 2026 Outstanding Women in Business awards, based on 83 nominations. These nominees were independently evaluated by two volunteer judges, who scored each on their professional achievements, community contribution and mentorship of young professionals. Samantha P. McDonald is a partner at Bowditch. She is an experienced, client-focused real estate lawyer, concentrating on business and real estate property law. She has been recognized as a WBJ Power 100 in the Class of 2026 and a “Top Women of Law” in Massachusetts Lawyers Weekly. Dr. Kavita Babu is chief medical officer and vice president of medical affairs at Heywood Healthcare, where she provides strategic and clinical leadership to advance high-quality, patient-centered care across the organization. She is also a member of the WBJ Outstanding Women in Business Class of 2025.
Hellblade studio Ninja Theory has started laying off staff, following Xbox’s announcement that it faces closure
Two separate agreements with the studio “fell through”…
Walmsley hopeful Grand Final role leads to new club
Departing Wakefield winger Lachlan Walmsley hopes his starring role in their Grand Final win over Warrington can help him pick up a new team.
ESPN predicts Auburn's remaining schedule after SEC loss to Tennessee
How did Auburn football's 2026 outlook change following its Week 5 loss to Tennessee?
Michael Douglas on 'immortality,' Kirk Douglas and the memories he once avoided
Michael Douglas, the award-winning actor and producer, recently turned 82 and has released a memoir titled “One Helluva Ride.” | 830 WCCO
Michael Douglas on 'immortality,' Kirk Douglas and the memories he once avoided
Michael Douglas, the award-winning actor and producer, recently turned 82 and has released a memoir titled “One Helluva Ride.” | WWJ Newsradio 950
DeSean Bishop Is the X-Factor Arkansas Must Contain
Arkansas knows exactly where Tennessee’s offensive plan begins. It begins with DeSean Bishop. The Volunteers running back enters Fayetteville after one of the best performances in the country this season. Bishop rushed 34 times for 220 yards and three touchdowns in Tennessee’s 24-14 win over Auburn, turning a game with quarterback uncertainty into a statement …
Eyes on Growth: TD Survey Finds Small Businesses Confident About Growth Despite Economic Headwinds and Delayed Investments
TD Bank U.S. survey finds 85% of small business owners expect stronger revenue through year-end, despite economic uncertainty and preparedness gaps.
German and US scientists win Nobel medicine prize for work on light and brain
The physiology or medicine prize traditionally opens the annual Nobel announcements.
From 4-H Member to Healthcare Leader: A Conversation with Davina Ferrero King
"My 4-H experience helped establish UConn in my mind as a place where I could continue growing academically, professionally, and personally."
Bruno Guimaraes Details Heavy Brazil Workload Ahead of Arsenal Return
Bruno Guimaraes has revealed the amount of travelling Brazil faced during a demanding international window before his return to Arsenal.
Asia-Pacific survey to employers and business membership organizations on labour, trade and responsible business conduct
This ILO Brief presents the results of a survey of employer and business membership organizations (EBMOs) in Asia and the Pacific highlights growing business demand for support in navigating labour, trade and responsible business requirements. The findings point to the need for stronger technical expertise, practical tools and sustained support to help businesses maintain competitiveness and meet evolving market expectations.
PEN America: Nearly 12,000 school book bans in a year, a record high
A new study from PEN America reveals that there were nearly 12,000 book bans in public schools over the past year, the highest since tracking began five years ago | 1010 WINS
Digital Science appoints Charlesworth as strategic sales partner of Altmetric and Dimensions in China’s scholarly publishing sector
Digital Science has appointed Charlesworth as its strategic sales partner of Altmetric and Dimensions in China’s scholarly publishing sector. This collaboration aims to support the growing demand for research data and information across this rapidly developing market.
Windber institute's data tracking system used by scientists far and wide
Developed by a member of the Chan Soon-Shiong Institute of Molecular Medicine at Windber, a system for using data to solve real-world problems caused by cancer is making a mark
Bromley Women 1-0 Reading Women: Match Report
The Royals are out of the cup, following a narrow defeat in South London on Sunday.
Colorado influencers cash in on campaign season
Paid political messaging is increasingly showing up in Colorado social media feeds, sometimes without voters knowing who paid for it.
Why plugged-in pickle glows: Engineer burns 100-plus pickles to find answer
An engineer says glowing pickles owe their orange light to sparks igniting hydrogen near an electrode, with sodium ions supplying the color.
German and US scientists win Nobel medicine prize for work on light and brain
They will share a prize sum of 12 million Swedish crowns ($1.2 million).
Ohio Democrats’ path to the governor’s office runs through rural areas that had turned against them
Democrats say their nominee for governor in Ohio, Dr. Amy Acton, represents the party’s best chance in years to win that office.
Ohio Democrats’ path to the governor’s office runs through rural areas that had turned against them
Democrats say their nominee for governor in Ohio, Dr. Amy Acton, represents the party’s best chance in years to win that office.
Hunt Marketing Firm in Oxford Receives Accolade
For the third consecutive year, Hunt Marketing in Oxford has earned a place on the Inc. 5000 list of America’s fastest-growing private companies. Hunt ranked No. 4,009 on the 2026 list. “Being named to the Inc. 5000 list for a third time is meaningful because it validates the growth story we’re building,” said CEO and […]
Northwestern Projected to Make College Football Playoff in Early Prediction
Northwestern is projected as the No. 10 seed in an early College Football Playoff bracket after the Wildcats’ dominant 34-13 win over Penn State.
Three Preseason Goals For Bulls' First Round Pick Dailyn Swain
To secure his place in Chicago’s future, the versatile rookie must rediscover his offensive aggression, leverage his elite defensive length, and prove he can impact winning beyond scoring.
Collaborating with Canadian Scientists on Marine Carbon Dioxide Removal Research
I first met Dr. Helen Gurney-Smith in fall 2024, when Dr. Shannon Meseck and I drove just beyond the U.S.-Canada border to the St. Andrews Biological Station in New Brunswick. We went there to study larval sea scallop respiration when exposed to near-future temperature and pH. This past winter, Dr.
Are the Brewers becoming more clutch in the Postseason?
Milwaukee’s ability in game one and two to comeback and win, makes this team feel that much more special
The Business of Civility
In an ever-coarsening world where even hosts on the bastion of conservative media, Fox News, are now using profanity on a regular basis, there is still one place where civility is demanded—and usually delivered. And that place is the business community. Whether you’re ordering a meal at McDonald’s or interviewing the wealthy CEO of Mississippi’s […]
Stanford Professor One Of Three Scientists Awarded The Nobel Prize In Medicine
Stanford professor Karl Deisseroth joins Peter Hegemann and Georg Nagel as winners of the 2026 Nobel Prize in Physiology or Medicine for their work on optogenetics.
Carlisle boss Elliot proud of squad after hard week
After a five-game winless streak, consecutive away wins have eased some of the pressure on Carlisle head coach Rob Elliot.
Swedish regulator temporarily revokes Charm Entertainment AB’s casino licence following investigation
Spelinspektionen issued an interim revocation of Charm Entertainment AB’s licence to operate commercial land-based casino gaming.
Nobel medicine prize goes to 3 scientists for research into brain activity
The Nobel Assembly praised their method, noting its global use in revealing brain mysteries.
Hurricanes Beat Flyers 3-2 In Overtime With Gostisbehere Heroics
The Carolina Hurricanes survived a scare in Philadelphia, using a former Flyer's power-play goal to secure a 3-2 overtime win.
Ace Combat 8 is far and away the series' biggest launch on Steam
Despite releasing in a busy period, Ace Combat 8: Wings of Theve has already set new records for the flight action series.
As Twin Cities suburbs grow more diverse, some old political patterns persist
City councils tend to be whiter than the places they represent. Some politicians and advocacy groups want that to change.
Game Preview: Winnipeg Jets @ Pittsburgh Penguins 10/5/2026
Who: Winnipeg Jets (1-0-1, 4th place Central Division) @ Pittsburgh Penguins (2-0-0, 1st place Metropolitan Division) When: 7:30 p.m. eastern How to Watch: Locally televised game on Sportsnet Pittsburgh, Sportsnet+ up in Canada, out-of-market streaming on ESPN+ Pens’ Path Ahead: Up next for the Penguins will be two road games against division opponent, Washington on Wednesday […]
NFL winners and losers: Nick Sirianni sucks
The Eagles are in trouble, and one man is to blame.
The Optimist: A statement win and a much needed rest
The Panthers head into a much needed bye week with head held high
Yale School of Medicine On the Science of Childhood Anxiety, Say, Anxiety Disorders Are the Most Common Mental Health Challenges In Youth
Credit: Matt Bradbury October 5, 2026 - By Isabella Backman - Anxiety disorders are the most common mental health challenges in youth. Left untreated, they can disrupt the lives of both children and their families. The good news is that with intervention, most children will overcome these conditions. Across Yale School of Medicine, scientists are working to understand anxiety at every level, from common anxious behaviors to molecular biomarkers in the brain. They are using their findings to develop and disseminate new evidence-based treatments for childhood anxiety. Today, the go-to treatment for childhood anxiety disorders is cognitive behavioral therapy (CBT). This is a form of psychotherapy that teaches children skills for confronting anxious thoughts and helps them practice managing situations that cause anxiety. While it is the gold-standard treatment backed by considerable scientific evidence, up to 50% of children will not see sufficient benefit from CBT alone. Wendy Silverman, PhD, Alfred A. Messer Professor in the Child Study Center, co-directs the Anxiety and Mood Disorders Program alongside Eli Lebowitz, PhD, associate professor in the Child Study Center. One of their main interests is learning how to improve outcomes beyond CBT. “We’re developing cutting-edge, research-based knowledge that can reduce the suffering that anxiety causes children and their families,” says Silverman. Changing parent behavior YSM experts are investigating how to improve CBT outcomes for children by involving the parents. Silverman’s research has uncovered two main components of parent intervention that improve childhood anxiety: not enabling children to completely avoid the things that make them anxious and taking steps to enhance their autonomy. Parents may unintentionally reinforce their child’s anxiety by allowing them to avoid what makes them anxious. They also may unintentionally limit the children’s sense of autonomy by being overly intrusive. “One of the things that we take pride in is that we’ve focused on trying to understand what parents need to do, and to test our ideas and see if changing the parents’ behaviors is enhancing the effects of CBT,” Silverman says. “Our findings thus far suggest that they do." As much as CBT can be helpful, it can also be challenging to get one’s child to do the necessary steps for CBT to work. This is one important reason why Lebowitz created a novel intervention program for parents named Supportive Parenting for Anxious Childhood Emotions (SPACE). Existing intervention programs often teach parents to act as therapists for their child, such as training them on how to practice breathing exercises. “It makes sense, but this doesn’t work very well in practice,” says Lebowitz. “And part of the reason, I think, is that it’s not easy to get your kid to do things, especially if they’re not excited about doing it.” SPACE is unique because it focuses entirely on parent involvement and changing parental behavior—children are not involved in the sessions. For example, parents learn how to use supportive messages that convey confidence that their child can tolerate and manage distress. “It might sound like a parent saying to a child, ‘I get that this is really hard for you, but I know that you can handle it,’” Lebowitz says. The program also works with parents to identify the ways in which they are accommodating anxious behaviors. “We’ll pick one thing that parents are doing that is an accommodation and help them make a detailed plan for how they’re going to change that,” Lebowitz explains. Treating Anxiety in Children and Adolescents Much of the existing research on SPACE has focused on parents of children under age 14. Ongoing studies are now exploring its use with parents of older teens. “Both anxiety and accommodation can interfere with normative developmental shifts during the teen years, including increased autonomy and individuation from parents,” says Rebecca Etkin, PhD, associate research scientist in the Child Study Center. “In this sense, SPACE may be particularly well-suited for anxious teens and their parents. We want to see whether it is effective during this distinct developmental window.” Unfortunately, many families in need of CBT face barriers, including limited availability of services and geographic constraints. One way to improve access is digital interventions. Silverman and her team are developing an evidence-based digitized intervention program for parents that they can access directly from their computer or smart phone. “The work we’re doing will be one of the very few parent interventions that is digitized and importantly tested for effectiveness,” she says. Creating interventions for anxiety-related challenges Silverman and Lebowitz recently received a generous gift to develop and test other interventions that help parents reduce other child anxiety-related behavioral and emotional difficulties, such as restrictive eating and unexplained somatic symptoms. One of these projects in particular focuses on understanding the risks of social media and its potential benefits, including offering a sense of connection. “A lot of research has focused on the idea that social media is harmful and the less of it the better,” says Lebowitz. “But we actually see is that this is not quite right—there are negatives, but there are also positives. So, we’re trying to get a little bit more nuanced of a picture.” The team is working with teens with social anxiety and their parents over an extended period to better understand their social media habits and how their anxiety levels affect engagement with different platforms. The teens will answer questions sent to an app on their phones about mood and social media usage in an effort to capture emotional responses as they unfold. “We hope to develop interventions that can help make the best of social media while protecting against the more problematic effects,” Lebowitz says. The brain’s role in anxiety Researchers are also testing therapies to address anxiety at the neurological and molecular levels. In collaboration with Dylan Gee, PhD, professor of psychology in Yale's Faculty of Arts and Sciences, and Hilary Blumberg, MD, John and Hope Furth Professor of Psychiatric Neuroscience at Yale School of Medicine, Lebowitz and Silverman are using brain imaging to identify changes in a child’s brain before and after parents enroll in SPACE. In one study, children viewed anxiety-inducing images while undergoing magnetic resonance imaging (MRI); the researchers conducted scans with and without the children’s parents nearby. Before SPACE, children’s brains were better able to activate the regulatory circuitry needed to turn off an anxious response when their parents were nearby. But after SPACE, children could activate this circuitry even without the parent around. “As parents work on gradually reducing some of their accommodations, you can see a child get better at regulating their own fear system in the brain,” Lebowitz says. “It’s remarkable.” Research into the molecular underpinnings of anxiety can also inform new childhood anxiety treatments. In a recent study, Lebowitz, Silverman, and Flora Vaccarino, MD, Harris Professor in the Child Study Center, discovered that a protein known as fibroblast growth factor 2 (FGF2) could be protective from the toxic effects of stress. FGF2 levels in children and their parents were linked to the children’s risk of developing anxiety and depression, the study showed. The findings could help explain why some children who are exposed to early life trauma such as poverty or abuse are more prone to developing mental health disorders. And FGF2 could be a target for treatment. “This is very novel because it starts to give a clue to what is the molecular chain that connects those lived experiences to the actual psychological outcomes,” Lebowitz says. New ways to study and treat childhood anxiety Michael Crowley, PhD, associate professor in the Child Study Center, collaborates with Silverman and Lebowitz to study the role that attention plays in development and maintenance of childhood anxiety. There is a large body of research that shows that anxious children, like anxious adults, are prone to focus on threatening stimuli such as angry faces compared with neutral faces. This has led to innovative interventions that involve attention retraining. The idea is that if experts train children to look away from threatening stimuli, it may reduce their anxiety—especially children with social anxiety who are most prone to attend to threats. The researchers have just completed a clinical trial for attention retraining with 10- to 14-year-olds with social anxiety disorders and are currently analyzing the findings. Besides this innovative attention retraining research, as Crowly notes, “I like to design tasks that are engaging to kids,” Crowley says. “My goal is to assess something without the kids knowing what we are assessing.” With this goal in mind, Crowley has created a virtual game, named Boom, to study threat processing in children with anxiety disorders. The game is similar to that of hot potato—the child and three digital players take turns virtually passing a ball to each other’s gloves. At some point, the ball turns into a bomb, and as the bomb lands in each player’s glove, the outline of the glove turns yellow. The goal is to avoid having the bomb go off in your glove. What isn’t obvious is that the game is designed to measure different types of threatening stimuli, both ambiguous and direct. In the game, the direct threat occurs as the bomb is traveling towards your glove. The ambiguous threat is the yellow outlined glove as it is unknown where the bomb will travel next. While children play the game, Crowley’s team measures their brain activity using electroencephalography (EEG). The researchers have discovered that in kids with anxiety, the brain reacts more strongly to ambiguous threats than it does in their peers, but less strongly to direct threats. They believe that the initial abnormally large brain response to not knowing where the bomb is going impairs the brain's ability to properly respond when the threat is actually traveling the child’s way. “The brains of children with anxiety are unable to differentiate between threats you need to do something about and those that are not your problem.” Michael Crowley, PhD, develops innovative games for studying anxiety in children and adolescents.Credit: Matt Bradbury Based on these insights, Crowley hopes to study whether interventions like attention training could restore appropriate threat processing. Crowley’s team is also working on a test called the Balloon Risk Avoidance Task, which evaluates risk-taking and avoidance behaviors. It features a digital balloon that is full of air and about to burst. Kids have six seconds to let air out of the balloon. The more air they let out, the less risk they face that the balloon will pop. But at the same time, the balloon becomes less valuable as it deflates. “The more air you keep in the balloon, the more points you get,” Crowley explains. So far, the researchers have found that when the balloons pop unexpectedly, teens with social anxiety show distinct brain responses. Studying these responses can help psychologists understand the underlying pathways driving the various manifestations of anxiety. The genetics of anxiety When Thomas Fernandez, MD, associate professor in the Child Study Center and of psychiatry, was still in training, there was a lot of excitement about understanding the genetics associated with autism spectrum disorder. Since then, scientists have identified around 250 genes associated with autism. The genetic contribution to anxiety disorders, on the other hand, has historically received less attention. Anxiety is less heritable than autism, but the genetic contribution for anxiety disorders that emerge in childhood may be higher than for anxiety disorders overall. While scientists estimate the heritability of anxiety disorders in general to be around 30% to 50%, some studies suggest higher heritability for certain childhood-onset anxiety presentations. “I saw firsthand how researchers in the field went about finding vulnerability genes for autism,” Fernandez says. “So, we’re using a very similar playbook for childhood anxiety.” “I saw firsthand how researchers in the field went about finding vulnerability genes for autism. So, we’re using a very similar playbook for childhood anxiety.” Thomas Fernandez, MD Associate Professor In the Child Study Center and in Psychiatry Now, Fernandez and Emily Olfson, MD, PhD, assistant professor in the Child Study Center, are studying children and their parents to identify genetic changes that are present in the child but not the parents, known as “de novo mutations.” “All of us have some de novo mutations—maybe about 50 to 100 sprinkled throughout the genome,” Olfson says. “But when they occur within the coding regions of genes, they can be really disruptive.” Previous research shows that people with autism have higher rates of damaging de novo mutations than the general population. In 2022, Olfson, Lebowitz, Silverman, and Fernandez published a study on 68 children and their families that found that children with anxiety had similarly high levels of these mutations. Studying de novo mutations can help point the researchers to where they should be looking for genes associated with anxiety. “The end game is using the genes to steer us toward the right part of biology that we can then target to come up with better treatments,” Fernandez says. Building on those findings, the team is now studying more families to better understand how these de novo mutations, along with other genetic and environmental factors, shape pediatric anxiety disorders. They recently received a National Institutes of Health grant to enroll 750 new families over the next five years. Olfson is the principal investigator, with co-investigators Lebowitz, Fernandez, Silverman, and Shuangge Steven Ma, PhD, department chair and professor of biostatistics at Yale School of Public Health. Neurodevelopment, Risk Genes, and Mental Health Conditions - The Olfson Lab Joel Gelernter, MD, Foundations Fund Professor of Psychiatry, is interested in how different anxiety disorders differ genomically. “We are studying social phobia, panic disorder, and generalized anxiety disorder, working to understand why people differ in their risk to these specific anxiety disorders and evaluating various risk factors,” he says. Gelernter was recently involved in one of the largest studies to date of the genomics underlying anxiety disorder. The study included around 122,000 people with anxiety disorders and around 730,000 without. It found that some genetic differences associated with anxiety were linked to signaling that helps reduce overactivity in the nervous system. Many anxiety medications available today work by targeting this process. “It’s nice when the biology that you get out of a large genome-wide study ratifies things that we already know because that can help increase confidence in further findings from the study,” Gelernter says. Uncovering the neurobiology of psychiatric disorders John Krystal, MD, Robert L. McNeil, Jr. Professor of Translational Research and chair of the Department of Psychiatry, is interested in the neurobiology of psychiatric disorders, including post-traumatic stress disorder (PTSD), of which anxiety is a major symptom. In the late 1980s, Krystal’s team discovered that the drug yohimbine activated symptoms in patients with PTSD. “This was the first time we could link a specific biological mechanism to the symptoms of PTSD,” Krystal says. At the time, he adds, this finding was highly controversial. “A lot of people felt that PTSD was a purely psychological syndrome that didn’t have an underlying biology.” Since then, Krystal has dived deep into understanding the neurobiology of PTSD to learn how to better treat it. His team is evaluating the use of ketamine and psychedelics. These would be among the first treatments to be developed specifically for PTSD. They may also be applicable for other disorders including anxiety disorders, Krystal adds. An important gap in PTSD treatment is the absence of biological tests that inform how to best help patients manage their PTSD symptoms. A doctor doesn’t diagnose cancer based on how they feel. Rather, they use tests of the biology of the cancer to determine the best course of treatment. “And we can’t do that in any psychiatric disorder other than Alzheimer’s disease,” Krystal says. “But now we are building a foundation for this approach to the treatment of anxiety disorders for the first time.” Source: Yale School of Medicine
Democratic socialists scored big primary wins. But that’s not the whole story.
DSA-backed candidates, sharp critics of Israel, made historic gains. But a closer look makes clear they’re not taking over the Democratic Party – so far.
Girls flag football is a fast-growing high school sport
Participation has surged more than 550% nationally in the past four years.
Northwest Arkansas growing pains, national concerns top issues at Springdale political gathering
Rain and overcast skies didn’t dampen the mood at the annual Chickin, Peelin’ & Politickin’ event Thursday at Springdale’s Shiloh Square as residents, business owners and elected officials networked over plates of fried chicken and shrimp.
'The Outsiders' review: A dynamic staging at the Hollywood Pantages
'The Outsiders,' winner of the 2024 Tony for best musical and based on the classic S.E. Hinton novel, has its L.A. premiere at the Hollywood Pantages Theatre.
Scientists win Nobel medicine prize for research into brain activity
Their work was lauded “for discoveries leading to optogenetics, which makes it possible to switch on, or off, the activity of individual nerve cells in a living brain.”
Central Asia's growing commitment to university sport on full display in Tashkent and Samarkand
The 1st Central Asia Student Sports Federations Forum, held from 29 September to 2 October 2026, brought together FISU leadership, FISU Central Asia and national university sports federations from across the region, confirming the growing political and institutional commitment to student sport in Central Asia. National delegations from Uzbekistan, Kazakhstan, Mongolia, Tajikistan and Kyrgyzstan attended […]
American Deisseroth and Germans Hegemann and Nagel win 2026 Nobel medicine prize
Scientists Karl Deisseroth, Peter Hegemann and Georg Nagel won the 2026 Nobel Prize in Physiology or Medicine for "discoveries concerning light-gated ion channels and optogenetics," the award-giving body said on Monday.
German and US scientists win Nobel Prize in medicine for research on brain activity
The trio won the award for their discoveries concerning light-gated ion channels and optogenetics. This neurobiology tool has provided new insights into how we might treat blindness, depression, addiction and dementia.
German and US scientists win Nobel Prize in medicine
The trio won the award for their discoveries concerning light-gated ion channels and optogenetics.
Scientists win Nobel Prize in medicine for work on ‘light-gated ion channels and optogenetics’
Scientists to Karl Deisseroth, Peter Hegemann and Georg Nagel won the 2026 Nobel Prize in Physiology or Medicine.
Buy Rating Reaffirmed Might Change The Case For Investing In Astrana Health Stock
Astrana Health recently reported quarterly results showing solid revenue growth and higher net profit for the period ending June 30, with a reaffirmed Buy rating from Freedom Capital Markets serving as supporting commentary on the business performance. The combination of rising quarterly profitability and revenue momentum suggests Astrana Health is executing on its healthcare model, with analyst confidence reflecting how that operating progress is being interpreted by the market. This...
Entertainment complex with restaurants, bar, arcade coming to Nine Mile
A new entertainment complex is coming soon to the growing Nine Mile area at 1420 W. Nine Mile Road offering upscale Southern Creole dining, immersive virtual reality gaming, draft beer and bourbon walls and more.
Who’s Winning the Battle for Congress?
It’s Oct. 5 — 29 days away from the midterms. Here’s the state of play.
Jesus: Cristiano Ronaldo will decide his Portugal future
Portugal boss Jorge Jesus has opened the door for Cristiano Ronaldo to resume his international career. Ronaldo left the national team squad after he was an unused substitute for a 2-1 win away to Norway in the Nations League on September 27.
Democrats Expect Record Number of Women in Party in House After Midterm Elections
Democrats are increasingly confident they will have a record number of women serving in the House next year, after backing women in competitive districts they are now positioned to win.
Anthropic expected to IPO despite market uncertainty, AI slowdown calls
Wall Street is gearing up for Anthropic’s expected mega initial public offering, a major test of investors’ appetite for one of the AI industry’s leading firms. Just weeks ago, its CEO called for an industry-wide slowdown over growing safety concerns.
The 10 Senate seats most likely to flip in 2026
Nearly four weeks out from Election Day, the Senate battleground map is growing after signs of improvement for Democrats in several red-leaning states.