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AFC Bournemouth vs Brentford: Is This A 'Must Win' Game?
Tomorrow, Cherries face an in form Brentford side that are yet to lose so far this season, and with European football soon to start, is this the first must win game of the season for Marco Rose's men?
Sweden's election could mark major milestone for Europe's populist right
Once shunned over its extremist roots, the Sweden Democrats could enter government for the first time as voters weigh immigration, crime and Sweden's political transformation.
‘The Europe she fought for will miss her’: Politicians pay tribute to Emma Bonino
The Italian civil rights activist and former European commissioner has died at the age of 78.
📸 This week’s viral Champions League images 🍿
The Champions League is wild! A look at the most bewildering moments from this European week, starting with Michael Olise’s hilarious — and now viral — interview on DAZN. Another surreal Olise ...
Emma Bonino, prominent humanist in Italian politics, dies at 78
A tireless defender of human rights, Emma Bonino served in the Italian and European parliaments, as foreign affairs minister, and as European commissioner. The historic figure of the Italian Radical Party died in Rome on Friday.
🗞️ Raphinha, Lamine Yamal and the Cesc effect: Friday's covers
The sports newspaper front pages this September 11 are packed with big names, continental surprises, and tensions handled in global boardrooms. Barcelona’s takeoff, Como’s European debut, and the ...
Major airline launches new business class suites with sliding doors
The new suites will be available on select flights to Europe and New York in 2027.
Taiwan vice president makes rare Europe visit for conference on democracy
European Parliament's Pina Picierno says Hsiao's visit 'was kept secret until her arrival to protect her participation'.
Wasps are disappearing this summer, and scientists are worried
Britain’s wasps have become mysteriously scarce this summer, and scientists suspect an unusual combination of temperature swings, heatwaves, and food shortages may be responsible. Even the wasps that remain appear unusually small, potentially offering a glimpse of how extreme heat could reshape insect populations.
Man Utd outclass Sabah on Champions League return
Manchester United cruised to a 4-0 win on their return to the Champions League for the first time in three seasons as Azerbaijani champions Sabah were taught a lesson on their debut among Europe's elite on Thursday.For coach Valdas Dambrauskas it was a return to Old Trafford after his fairytale rise to the Champions League began with a role at Manchester United Soccer Schools, while working several part-time jobs just to make ends meet.
Sabah make crazy UCL history despite Man Utd humbling 🌍
Sabah's opening Champions League encounter was always set to be historic.The reigning Azerbaijani champions made their foray into Europe's elite club competition with a prestige meeting against Manche...
How geopolitical rifts cut scientific collaboration
Researchers have measured how worsening geopolitical relations hobble scientific collaboration, at last quantifying the impact of rifts between governments on cooperation between labs. Over the last decade, a tenser world has thrown up new barriers to cross-border science. Collaboration between the US and China has dimmed as the two countries have sunk into an ever-deeper rivalry. Links between Russia and Europe have collapsed following Moscow’s full-scale invasion of Ukraine. But while a concern, the magnitude of the damage is less than might be expected. For all the geopolitical turmoil of the last decade, international scientific collaborations are near a record high. “Some part of the story is positive,” said Shreyas Gadgin Matha, a social scientist at Harvard University and an author of the new study. “Research collaborations are largely resilient.” Matha and colleagues looked at data on cross-border research papers and patents in the period 2000-23, and analysed how they were impacted by countries’ political relations, as measured by how often states voted together in the United Nations. They found that when states drift apart at the UN by the median difference in votes between all countries, joint scientific papers decline by 3.1% over the next three-year period. To put that in context, over the last decade, the US and China have diverged by around a third of that difference in votes every three years. In other words, on average, it takes quite a significant diplomatic rift even to trigger a small single-digit percentage drop in joint papers. “In the short term, even something like a 3% reduction [in joint papers] is, in some ways, not that big of a number,” said Matha. Research remains more international than ever, according to an analysis extending to 2023 released by the Organisation for Economic Cooperation and Development (OECD) in 2025. We’re still living in an era of unprecedented scientific globalisation, the analysis says, with 27% of papers in OECD countries written across borders. In 1970, just 2% of articles had authors from different countries. Longer-term damage?However, this trend towards increasing international collaboration “has lost momentum and might be partly breaking down,” the OECD analysis says, largely due to a fall in the intensity of US-China joint papers since 2018. Matha and his colleagues stressed they are not complacent about the global science system. For now, “it's pretty resilient,” said co-author Muhammed Yildirim, director of academic research at Harvard’s Growth Lab. But if links are weakened, through the denial of study visas, for example, then this could have a much longer-term effect, cascading through generations of scientists, he added. Related articlesChina becomes Russia’s biggest collaborator after war decimates science ties with the west US scientists prefer German to Chinese collaborators, study finds Horizon Europe is now truly global. But what comes next? Another finding of the study, Burning bridges or bridging divides: Geopolitics and collaboration in research and innovation, is that trust appears easier to destroy than create.The hit to scientific collaboration when countries drift apart is around three times as big as the growth in joint papers when they move closer, the paper finds. “It's far easier to break these ties than to mend them, and that that also perhaps has some larger policy lesson,” said Matha.PatentsThe results around patents were less clear cut. Some methods of analysis found a statistically significant link between a diplomatic rift and a drop in co-patenting, but others did not. According to Yildirim, patents with cross-border inventors are often developed by multinational companies, which may have invested heavily in global R&D facilities, so are less likely to change how they operate simply due to a change in the geopolitical weather. “That's why we might not be seeing the effect immediately in technology,” he said.By contrast, researchers might be more sensitive to geopolitics, because visa policies can quickly affect who meets who at academic conferences, he went on. International collaboration on patents is much lower than for academic articles, the study shows. It peaked at around 10% in 2010, and has since fallen back to around 8%. This could be because China dramatically ramped up domestic patents in the 2010s, said Yildirim, squeezing the international share.
How geopolitical rifts cut scientific collaboration
Researchers have measured how worsening geopolitical relations hobble scientific collaboration, at last quantifying the impact of rifts between governments on cooperation between labs. Over the last decade, a tenser world has thrown up new barriers to cross-border science. Collaboration between the US and China has dimmed as the two countries have sunk into an ever-deeper rivalry. Links between Russia and Europe have collapsed following Moscow’s full-scale invasion of Ukraine. But while a concern, the magnitude of the damage is less than might be expected. For all the geopolitical turmoil of the last decade, international scientific collaborations are near a record high. “Some part of the story is positive,” said Shreyas Gadgin Matha, a social scientist at Harvard University and an author of the new study. “Research collaborations are largely resilient.” Matha and colleagues looked at data on cross-border research papers and patents in the period 2000-23, and analysed how they were impacted by countries’ political relations, as measured by how often states voted together in the United Nations. They found that when states drift apart at the UN by the median difference in votes between all countries, joint scientific papers decline by 3.1% over the next three-year period. To put that in context, over the last decade, the US and China have diverged by around a third of that difference in votes every three years. In other words, on average, it takes quite a significant diplomatic rift even to trigger a small single-digit percentage drop in joint papers. “In the short term, even something like a 3% reduction [in joint papers] is, in some ways, not that big of a number,” said Matha. Research remains more international than ever, according to an analysis extending to 2023 released by the Organisation for Economic Cooperation and Development (OECD) in 2025. We’re still living in an era of unprecedented scientific globalisation, the analysis says, with 27% of papers in OECD countries written across borders. In 1970, just 2% of articles had authors from different countries. Longer-term damage?However, this trend towards increasing international collaboration “has lost momentum and might be partly breaking down,” the OECD analysis says, largely due to a fall in the intensity of US-China joint papers since 2018. Matha and his colleagues stressed they are not complacent about the global science system. For now, “it's pretty resilient,” said co-author Muhammed Yildirim, director of academic research at Harvard’s Growth Lab. But if links are weakened, through the denial of study visas, for example, then this could have a much longer-term effect, cascading through generations of scientists, he added. Related articlesChina becomes Russia’s biggest collaborator after war decimates science ties with the west US scientists prefer German to Chinese collaborators, study finds Horizon Europe is now truly global. But what comes next? Another finding of the study, Burning bridges or bridging divides: Geopolitics and collaboration in research and innovation, is that trust appears easier to destroy than create.The hit to scientific collaboration when countries drift apart is around three times as big as the growth in joint papers when they move closer, the paper finds. “It's far easier to break these ties than to mend them, and that that also perhaps has some larger policy lesson,” said Matha.PatentsThe results around patents were less clear cut. Some methods of analysis found a statistically significant link between a diplomatic rift and a drop in co-patenting, but others did not. According to Yildirim, patents with cross-border inventors are often developed by multinational companies, which may have invested heavily in global R&D facilities, so are less likely to change how they operate simply due to a change in the geopolitical weather. “That's why we might not be seeing the effect immediately in technology,” he said.By contrast, researchers might be more sensitive to geopolitics, because visa policies can quickly affect who meets who at academic conferences, he went on. International collaboration on patents is much lower than for academic articles, the study shows. It peaked at around 10% in 2010, and has since fallen back to around 8%. This could be because China dramatically ramped up domestic patents in the 2010s, said Yildirim, squeezing the international share.
Scientists say August was Earth's hottest month they've measured
The European climate service Copernicus said the Earth just sweltered through its hottest month on record in August. Scientists said the heat surge is mostly due to human-caused climate change.
The Sidemen Rep Arcade Signs Max Fosh, Friends From Work & More Ahead Of Europe’s First Creator Upfront
EXCLUSIVE: Arcade, the management company of The Sidemen, has signed a host of creators, as it relaunches as an entertainment business ahead of its first European upfront. Comedian Max Fosh, creator c...
Spanish Grand Prix 2026: Can football-obsessed Madrid embrace F1?
After F1’s explosion in popularity away from its European heartland the sport is coming home. Why Madrid? Because it is beautiful… and has a very big expo centre on the outskirts.
Yourgene Health Insight DPYD assay achieves IVDR accreditation
Yourgene Health (part of the Novacyt Group), an international molecular diagnostics company with a broad portfolio of integrated technologies and services, announces the commercial launch of its In Vitro Diagnostic Regulation (IVDR)-certified Yourgene® Insight DPYD assay, expanding the Company's clinical genetics portfolio across regulated European markets.
Yourgene Health launches Insight DPYD assay (IVDR)
Yourgene Health (part of the Novacyt Group), an international molecular diagnostics company with a broad portfolio of integrated technologies and services, announces the commercial launch of its In Vitro Diagnostic Regulation (IVDR)-certified Yourgene® Insight DPYD assay, expanding the Company's clinical genetics portfolio across regulated European markets.
Global heat stuck on high. Scientists say August was Earth’s hottest month they’ve measured.
The European climate service Copernicus said the Earth just sweltered through its hottest month on record in August.
Global heat stuck on high. Scientists say August was Earth's hottest month they've measured.
The European climate service Copernicus said the Earth just sweltered through its hottest month on record in August
Global heat stuck on high. Scientists say August was Earth's hottest month they've measured.
The European climate service Copernicus said the Earth just sweltered through its hottest month on record in August.
Viewpoint: Unlocking Europe’s wildfire data
Europe is already investing in the science, technology and infrastructure needed to understand, prevent and fight wildfires. Copernicus provides satellite-based Earth observation and environmental information, while the European Forest Fire Information System provides information on fire danger and forest fires across Europe. Weather and climate systems add forecasts of heat, drought, wind and humidity; historical fire databases show where fires have occurred; and researchers generate increasingly detailed knowledge about fuels, fire behaviour, forecasting, modelling and risk management. Meanwhile, new European research projects are adding digital twins and other tools to this growing ecosystem.However, these data do not necessarily sit together, nor are they necessarily described, structured or governed in ways that allow them to be used together. Much of the information is public, but some is commercially held. Some is sensitive. Some is subject to legal, security or operational restrictions. Even when data can be legally accessed, different systems may use different formats, terminology and rules.Europe therefore faces an unusual paradox: we have vast amounts of relevant information to respond to the wildfire challenge, but not the means to bring it together. For example, a wildfire researcher or emergency service might need to ask whether a particular combination of vegetation, drought, wind and topography has historically been associated with rapid fire spread. The relevant information may exist in several institutions, using different systems and subject to different conditions of access.The challenge is to conduct an authorised analysis that interacts with these sources, combines the results and respects the rules imposed by each data custodian.An important part of the answer can be found in the Fair principles, the idea that data should be findable, accessible, interoperable and reusable. Developed more than a decade ago, these principles have become a central reference point for modern data stewardship, making it easier for people and machines to find data, understand what it means and determine whether it can be reused.Readability by machines is essential, since AI systems will be key to meeting the data challenge. Bring analysis to the dataThe proposition is not to give an AI system unrestricted access to sensitive databases. Quite the opposite. The goal is to make it possible for approved algorithms to go to the data, rather than requiring sensitive data or large datasets to be copied to wherever the analysis happens.Imagine an analysis asking a series of questions of different data stations. At one station it might examine weather and climate data; at another, historical fire records; at another, experimental measurements of fire behaviour. The algorithm does not need to download everything. It can operate within the environment permitted by each data custodian and return only the results that the rules allow to leave.This is sometimes described as data visiting, and related approaches already exist in areas such as federated analysis and federated learning.Sensitive data should therefore not be treated as a free-for-all for machines. This requires appropriate governance at multiple levels. Access needs to be authenticated and authorised. The purpose of an analysis should be defined. The code or model being run should be controlled. Data custodians should be able to specify what can be queried and what results can leave their environment. Activities should be auditable and human oversight should remain where the consequences require it.In other words, the objective is not to trust AI with the data. It is to design systems in which AI never has more access than it needs.As open as possible, as closed as necessaryFair data should also not be confused with open data. Some wildfire data should be openly available. Other information may legitimately need to remain restricted because it concerns critical infrastructure, security, commercial interests, privacy or operational capabilities. The principle should be: as open as possible, as closed as necessary.The important point is that restricted data should not automatically become unusable data. If machines can discover what information exists, understand its meaning, establish where it came from and determine the conditions under which it can be used, authorised analyses can potentially be carried out without the underlying data ever leaving the environment in which it is protected.Restricted data can still be Fair and machine-actionable.This is also an important question of data sovereignty. European institutions should not have to surrender control of their data to a handful of technology platforms in order to benefit from AI. Nor does Europe need to start again by building one giant repository for every piece of wildfire information. The better approach is to connect what already exists.This is the principle behind emerging approaches such as Tryangle, developed through the Leiden Initiative for Fair and Equitable Science. Rather than creating another centralised data warehouse, the approach seeks to provide an interoperable layer through which approved algorithms can visit distributed data sources while respecting the rules of their custodians.In this way, a data station can remain where it is. Its custodians can retain control. Existing databases and applications do not have to be abandoned. What changes is their ability to communicate with other systems through common, machine-readable descriptions, access rules and interoperability mechanisms.But approaches like this need data that meets the Fair principles. Only then can an interoperable ecosystem safely begin to turn fragmented information into collective intelligence.Data infrastructure is wildfire infrastructureThe implications of this approach are entirely practical. Firefighters could gain better intelligence about local and evolving risks. Land managers could test prevention strategies using more comprehensive information about fuels, weather and past fires. Researchers could compare evidence across ecosystems without repeatedly moving huge datasets between institutions. Smaller regions and resource-constrained teams could access analytical capabilities without having to build large data infrastructures themselves.Europe is already investing heavily in satellites, databases, research programmes, forecasting systems and scientific expertise. The question is whether we will connect those investments well enough to turn them into actionable intelligence.That requires policymakers and funders to treat data infrastructure as seriously as physical infrastructure. Data generated or supported through European public funding should be Fair, verifiable and machine actionable by design, wherever legally and ethically possible.Related articlesData Corner: Europe’s burning need for wildfire mitigation researchClimate monitoring must remain a global enterprise, experts sayIn practice, that means funding not only the production of data, but also the infrastructure that makes data usable across systems: metadata, provenance, interoperability, access mechanisms and governance. Where data must remain restricted, we should ensure that it can still be securely discovered, verified and used for authorised analysis.Initiatives such as the European Open Science Cloud offer an existing framework through which these principles can be put into practice. What is needed now is to accelerate implementation and make them a standard part of how Europe funds and builds research and innovation systems.We do not need another generation of disconnected databases. The data is already there. The opportunity is to make it work together, securely, responsibly and quickly enough to help prevent the next fire, rather than simply document the last one.Jean-Claude Burgelman is professor emeritus at the Free University of Brussels (VUB) and editor-in-chief at Frontiers Policy Lab. For more than 20 years he held leading roles in research and innovation policy at the European Commission.
Flying Car With (Tiny) NH Angle Gets the OK in Europe: Business NH Magazine
PAL-V, the Dutch firm that has been working for decades on a flying car held aloft by a helicopter-like rotor, has gotten a production license from the European aviation safety agency.
Boston Dynamics spinoff looks to build robots for entertainment
Dynamic Creatures is building theme park robots on Chinese hardware. Europe's own social robotics champion was sold to a Shenzhen buyer last year.
Nine Years Since Brighton's First Ever Premier League Win
Relive the historic afternoon a Pascal Groß masterclass dismantled West Brom, sparking a transformative journey from top-flight newcomers to European contenders under the lights of the Amex.
Yourgene Health Releases IVDR-Certified DPYD Assay for Chemotherapy Toxicity Detection
Yourgene Health launches IVDR-certified DPYD assay in Europe to detect 19 variants linked to fluoropyrimidine chemotherapy toxicity.
OneSkies Makes Business Class More Accessible
TAMPA, Fla., Sept. 09, 2026 (GLOBE NEWSWIRE) -- OneSkies, a travel service focused on premium international airfare, is helping U.S. travelers explore competitive business class flight options for long-haul trips to destinations across Europe, Asia, the Middle East and beyond. As travelers increasingly prioritize comfort on international journeys, business class is attracting interest beyond traditional corporate travel. Vacationers, entrepreneurs, couples, families and experienced travelers are
Barcelona vs Feyenoord, Champions League: TV & Streaming, Live Thread
Join us for the first Barcelona European adventure of the season!
Jeremy Farrar Joins Global Health Non-Profit PATH Following Unexpected Departure From WHO
Outgoing WHO Assistant Director-General Dr Jeremy Farrar will lead PATH’s regional division for Asia, the Middle East, and Europe starting 1 October. Based in Geneva, he joins the executive leadership team to accelerate the delivery of health technologies across these regions, the organisation announced in a press release on Wednesday, 9 September.
Germany must relearn the language of power-politics
To protect Europe from Russian aggression, Germans must resolve a tension that lies the heart of their modern national identity: a clash between the ideals of ‘Never Again Fascism’ and ‘Never Again Germany’.
JPMorgan expands corporate banking business to Greece
JPMorgan has expanded its corporate banking business to Greece, the U.S. bank said on Wednesday, as part of a broader plan to grow its services for companies across Europe.
Europeans struggle to imagine 'credible' future, study finds
New research identifies an 'imagination gap' as where political choices can still matter
Europeans struggle to imagine 'credible' future, finds study
New research identifies an 'imagination gap' as where political choices can still matter
Belgium battle could be a blessing
It is a new chapter for Aston Villa and, against Club Brugge, they turned the page. A first win of the season, albeit more nervy than anticipated, lit the spark for Unai Emery's side. The visitors were in a commanding and deserved position at half-time, John McGinn's opener making him the club's all-time record European goalscorer with 12.
Seagulls must learn from slow start
It's been a busy start to the 2026-27 campaign for Brighton and Fabian Hurzeler must now begin to prepare for a packed schedule of domestic and European football. Although the Seagulls will wait until October for their Conference League league phase to start, Hurzeler's side has endured a flurry of mixed results in their opening five games of the season. After a bruising 4-3 loss at Stamford Bridge to transfer-foes Chelsea, Brighton were lucky to escape with a 1-1 draw at home to Leeds.
Champions League
A new edition of the UEFA Champions League is under way, with Inter opening their 2026/27 European campaign with a defeat away to Real Madrid. Europe’s premier club competition will now take a break...
Real Madrid, PSG, Liverpool: Ranking Europe's greatest dynasties
Paris St-Germain are eyeing a third successive Champions League crown, but where do they rank against Europe's most dominant clubs?
Porto vs Manchester City Match: Champions League Live Updates
Porto hosts Manchester City at the Estádio do Dragão on Tuesday, September 8, in the opening round of the 2026-27 UEFA Champions League phase. Both teams enter the European opener in strong domestic form and will be looking to start their Champions League campaigns with a positive result. Kickoff is scheduled for 8 p.m. BST, […] The post Porto vs Manchester City Match: Champions League Live Updates appeared first on HEAVY.
Years before Nepal floods, scientists pitched a seismic warning system
The scientists, who are based in Europe, say the system could have triggered lifesaving alerts before floodwaters hit in Nepal. But the concept is unproven in the field.
Eutelsat Wins Further Connectivity Business in Greenland
Eutelsat is going to help to bring better connectivity to Greenland. Alongside the European Union, the government of Greenland and the government of
Cannibalism returned to the menu multiple times in Neolithic Europe
Bones collected from three caves in Spain reveal how cannibalism came back over thousands of years.
Allegri counts on European 'motivation and adrenaline' for Napoli
Coach Massimiliano Allegri is hoping the arrival of Champions League football can help put Napoli on the right track after back-to-back defeats in Serie A. Victory on the opening day against Genoa has been undermined by successive defeats at the hands of Como and Inter Milan, leaving new boss Allegri looking for a reset when his side welcome Arsenal to Stadio Diego Armando Maradona on Wednesday evening.
The best gadgets and gear that debuted at IFA 2026
Why wait for the future of technology to arrive when you can see it now? Here are the most exciting gadgets from Europe's biggest tech expo.
🚨XIs ready: City visit Porto in their European opener
Estádio do Dragão is getting ready to host an electrifying UEFA Champions League opener. Francesco Farioli’s FC Porto come into it on fire after putting together seven straight wins and opening th...
🚨Confirmed XIs: Dortmund host Villarreal in their European opener
The 2026/27 UEFA Champions League kicks off in style at the mystical Signal Iduna Park. Borussia Dortmund come in as favorites, backed by three straight wins and Serhou Guirassy’s firepower up front...
Current events: Scientists keep close eye on Atlantic Ocean changes
The year is 2060. London shudders through months of Nordic winter freezes. Across northern Europe, oak and beech forests wither under severe frost and drought, while cereal yields collapse from temperatures ...
AZ's R&D chief Barr touts internal 'science success story' after IL-33 antibody's stellar showing in COPD
With a detailed data drop that AstraZeneca’s R&D chief described as an internal “science success story,” the British Big Pharma has secured an FDA priority review for what it believes could become a flagship biologic in chronic obstructive pulmonary disease (COPD). In detailed results from the late-stage Oberon and Titania trials—first teased in March and detailed in full at the European Respiratory Society Congress in Barcelona this week—the drugmaker laid out the extent of its IL-33 inhibitor’s potential to reduce moderate and severe exacerbations in a wide range of COPD patients still struggling with those “lung attacks,” as AstraZeneca’s Sharon Barr, Ph.D., called them, despite using standard-care inhaled therapy. In the headline results, a 300 mg dose of tozorakimab given once every four weeks curbed those moderate and severe exacerbations in the studies’ primary population of former smokers by 29% in the Oberon study and 34% in Titania. In the overall population of both current and former smokers, these reductions were 30% and 29%, respectively, versus placebo and inhaled standard of care. The benefits also extended to clinically meaningful exacerbation reductions in all prespecified patient subgroups and specifically turned up promising signals in patients across a range of blood eosinophil counts, with Barr telling Fierce that “it’s the details that make this even more exciting than the high-level results that we’ve already shared.” In fact, during AZ’s tozorakimab poster presentation at the ERS 2026 Congress this past weekend, attendees were so enamored by the data that event organizers had to encourage people to clear the room and look at the other presentations on offer, Barr said in an interview. “I think it really speaks to the fact that there is a lot of buzz around these data because the entire respiratory community has been so desperate for new therapies for these patients,” she explained. The respiratory disease continues to represent a “staggering unmet medical need,” Barr said, highlighting the COPD exacerbations that the Oberon and Titania studies homed in on, which she added carry a greater mortality risk than a heart attack. “When a patient has a severe exacerbation, only about half of them are still alive within three and a half years,” she pointed out. As for tozorakimab specifically, Barr christened the molecule “an AstraZeneca science success story,” harkening several years back to the point at which researchers began to explore IL-33 as a driver of respiratory disease, and COPD in particular. At the same time, “there was still so much that wasn’t understood,” she admitted, highlighting the insight that IL-33 signals through both ST2 and EGFR through the RAGE pathway, a discovery Barr attributed to AstraZeneca's own scientists. Understanding the need to tackle both pathways in COPD—and aware of competitor candidates in the hopper, including one that bound ST2—the company ultimately had to make some “courageous decisions,” Barr said. These included taking a prior COPD molecule offline and going back to the drawing board to reinvent its potential IL-33 label “to make sure that we had a molecule that could block signaling through both arms of the pathway, through both the reduced form and the oxidized form, knowing that we wouldn’t be first, but striving to be best.” “When we put [tozorakimab] into the clinic, we firmly believed that we had a differentiated molecule, and we saw the other molecules blocking just ST2 or partially blocking IL-33, unable to deliver two positive pivotal studies in COPD,” Barr explained. “We kept marching forward because we believed our molecule was differentiated, and now I think we have the clinical validation that supports that.” Ultimately, AstraZeneca finds itself on much better footing these days when it comes to potential biologic rivals to tozorakimab in COPD. Sanofi and Regeneron’s Dupixent, for instance, is approved to treat COPD exacerbations in patients with high eosinophil counts, but not low ones. Meanwhile, the future has become cloudier for other next-gen IL-33 candidates from Sanofi and Regeneron, as well as Roche, which have suffered trial flops in recent years. One other potential ingredient for AstraZeneca’s success in its duo of studies was that the company was “ambitious in the trial design, willing to look at an all-comers population,” Barr said, “and willing to enroll the most severe patients.” Prior studies for would-be biologics rivals in COPD “avoided enrolling” those patients, she pointed out. She also highlighted the Big Pharma’s painstaking design of exacerbations in its trial, which “gave us a very rigorous readout,” and pointed to “the extra effort and investment” the company put in to understand the effect of mucus plugs in patients. Barr described mucus production as a “key feature in disease diversity,” noting that mucus plugs—obstructing clumps of mucus that block patients’ airways—are associated with worse outcomes in COPD. In its data announcement, AstraZeneca noted that an integrated analysis of Oberon and Titania found tozorakimab “demonstrated a reduction in patients’ mucus plug score,” with the pharma claiming its biologic is the first to deliver such results in a broad COPD population. “So being able to reduce those mucus plugs, we expect, is an important part of driving benefit for patients who are living with COPD,” Barr said. Again touching on the breadth of the study populations, Barr added that tozorakimab “worked across all eosinophil levels in both current and former smokers across all levels of lung function,” which she suggested “really simplifies decision-making for clinicians, and it allows them to offer therapy to the broadest possible patient population.” In the highest patient eosinophil count group, tozorakimab helped chart a 43% reduction in exacerbation risk, which Barr stressed were “unprecedented data.” In the mid-level group, AZ’s drug delivered a 23% reduction and, in the lowest group, a 34% reduction in eosinophils, which Barr said suggests efficacy “in all patient subgroups.” As for AZ’s recent guidance upgrade on the medicine’s sales opportunity, the lift from a $3 billion to $5 billion range to $5 billion plus was informed by multiple factors, Barr said, including the fact that “in 2024, there were multiple competitors, and there aren’t anymore.” Additionally, “we know that this is a massive unmet medical need, and this is a really incredible set of data that we think will be very convincing to the clinical community,” Barr said. Looking ahead to a potential evolution of the COPD treatment landscape, Barr noted that most patients start treatment in the community with an option like a triple therapy, and for them, having an option like AstraZeneca’s inhaler Breztri will remain a “really important part” of that journey. But of the patients uncontrolled on triple therapy, which Barr described as “about half of them today,” just a “small fraction” are currently eligible for biologic therapy, which she emphasized AstraZeneca is working to change. Understanding that COPD is not a “one-size-fits-all” disease, AstraZeneca is also looking at its antibody drug Tezspire for patients with T2-driven disease, and the company continues to think about new mechanisms for tackling COPD through both systemic and inhaled drugs, Barr said.
Champions League Matchday One: Four things to watch
The Champions League is back this week as Europe's elite begin their pursuit of club football's biggest prize.Matchday one brings blockbuster reunions, unwanted records and plenty of questions for som...
Mistral raises €3B as sovereign AI becomes big business
The French AI lab has raised €3 billion at a €21 billion valuation in a Series D round led by Samsung, Scaleup Europe and PSG Equity.
Apple Acquires Startup Working on 'Breakthrough Sensing Technology'
Earlier this year, Apple acquired California-based startup Sonera, according to a notice published today on the European Commission's website. Sonera previously announced that it had developed "breakthrough sensing technology" that "non-invasively measures magnetic fields" generated by the brain and body. The company said its technology can analyze neural data without direct skin contact, giving it an advantage over traditional electrical sensing techniques.
Legal complaint against FIFA to cover impact on women’s schedule
A legal complaint against FIFA has been extended to cover its “abusive conduct” towards the women’s game in Europe. The complaint by the European Leagues umbrella group, which includes the Premier League and Scottish Professional Football League (SPFL) as members, was first lodged with the European Commission in October 2024.
Legal action against Fifa to include women's schedule
Legal action from the top European leagues and global players' union Fifpro against Fifa is extended to include the world governing body's "abusive conduct" towards the women's game.
📺 Follow Napoli's UEFA Champions League journey on NOW!
Napoli are back in the Champions League and getting ready for a new European season packed with major challenges. Massimiliano Allegri’s side will face Arsenal, Manchester City, Porto, Villarreal, C...
📺 Follow Roma’s Champions League journey live on NOW!
After seven years away, Roma are back in the Champions League. Gian Piero Gasperini’s Giallorossi are ready to test themselves against some of Europe’s best teams, including Real Madrid, PSG and M...
Arsenal Predicted XI vs Napoli as Arteta Handed Injury Boost
Mikel Arteta faces a selection dilemma in Naples as key stars return. Discover how Bruno Guimaraes and Ebere Eze could spearhead a refreshed lineup seeking European redemption.
Qualitas Energy buys Cero Generation’s 5.8GW European renewables business
Renewables investment platform Qualitas Energy has bought Cero Generation’s 5.8GW European solar PV and energy storage project portfolio.
UEFA Champions League: Tuesday, Sept. 8 Preview and Predictions
The 2026-27 Champions League is finally here. After months of domestic buildup and qualifying drama, the league phase kicks off tonight with a full slate of intriguing openers. New managers, rebuilt squads, and familiar rivalries all collide as Europe’s elite return to the biggest stage. Here are the predictions for all six matches on opening […] The post UEFA Champions League: Tuesday, Sept. 8 Preview and Predictions appeared first on HEAVY.
Roma slash 26/27 wage bill by 14%
Roma, as stated by Tony D’Amico, has lowered its wage bill as requested by UEFA to send a positive message to European football’s governing body. The Roman club is moving toward sustainability, wh...
Exclusive: Daryl Mitchell backs ETPL to produce cricket's next superstars
Daryl Mitchell is one of the big names taking part in the inaugural European T20 Premier League this season with the Dublin Guardians, and the New Zealand international is backing the new franchise league to make a huge mark.
Eight Italy hopefuls to watch in Tuesday’s Champions League matches
Champions League football gets underway for the 2026-27 season on Tuesday evening, and ahead of kick-off at 17.45 BST, here is a look at the eight Italy hopefuls that could be involved in European act...
Jose Mourinho: Will Real Madrid begin their Champions League campaign with a win against Inter?
Jose Mourinho begins his second Real Madrid spell in the Champions League against former club Inter Milan, 16 years after winning the trophy with Inter at the Bernabeu. Will he finally deliver European glory in Madrid?
Europe has plans for cancer and heart disease – lung health is still waiting
Getting respiratory care right could help patients, ease hospital pressure and cut emissions all at once – but Europe still lacks a plan to make it happen
French A.I. Start-Up Mistral Raises $3.5 Billion as Part of Strategy Shift
Mistral is trying to keep pace with American and Chinese rivals while offering customers a European alternative for artificial intelligence.
Where Is the UEFA Champions League 2026?
The 2026 UEFA Champions League final was held at the Puskás Aréna in Budapest, Hungary, on May 30, 2026. Paris Saint-Germain faced Arsenal in the final, with PSG winning the trophy.The new 2026–27 UEFA Champions League season is different because its matches are being played across Europe. The 36 teams in the league phase play […] The post Where Is the UEFA Champions League 2026? appeared first on HEAVY.
Thriston Lawrence rallies from 6 behind and beats Paul Casey in a playoff in Switzerland
Thriston Lawrence is a winner for the third time in five years at the European Masters. This one took a final-round 62 and four playoff holes to beat Paul Casey.
EU seeks to reassure a Trump-rattled Greenland with promise of a new partnership and investment
The European Union is promising Greenland a stronger partnership and hundreds of millions of euros in investment, wanting to reassure Greenland after U.S. President Donald Trump's threats to take control of the island.
Champions League Is Back! TV Channels, Live Stream, Kickoff Times
The UEFA Champions League is back, and this midweek belongs entirely to Europe’s biggest club competition. With the Europa League and Conference League still waiting to begin their league phases, the Champions League takes over three days — Tuesday, Wednesday and Thursday — for a packed 18-game opening Matchday. UEFA’s official 2026-27 Champions League schedule […] The post Champions League Is Back! TV Channels, Live Stream, Kickoff Times appeared first on HEAVY.
Business Rules Management System Market to Reach $4.20 Billion by 2035 as AI-Driven Decision Automation Accelerates
The U.S. Business Rules Management System Market is Projected to Grow from $0.47 Billion in 2025 to $1.09 Billion by 2035, While Europe is Expected to Expand from $0.54 Billion to $1.36 Billion, Driven by Real-Time Decision-Making, Regulatory Compliance, Enterprise Automation, and Rising Adoption of AI- and Machine Learning-Enabled Business Rules PlatformsAustin, United States, Sept. 07, 2026 (GLOBE NEWSWIRE) -- The Business Rules Management System Market was valued at USD 1.79 Billion in 2025 a
Business Rules Management System Market to Reach $4.20 Billion by 2035 as AI-Driven Decision Automation Accelerates
The U.S. Business Rules Management System Market is Projected to Grow from $0.47 Billion in 2025 to $1.09 Billion by 2035, While Europe is Expected to...
Burnham’s UK‑first politics meet a more protectionist EU and its ‘Made in Europe’ plan
The new UK prime minister has focused on domestic policy so far, but wants a close relationship with EU. How can that be reconciled with the EU's new protectionist 'Made in Europe' agenda?
Barcelona youngster could be handed minutes vs Feyenoord
An up-and-coming member of the attacking ranks at La Liga giants Barcelona could yet be afforded minutes off the bench in the club’s European season opener.This comes amid confirmation that Jesse Bi...
Ratko Mladić funeral exposes gap between Serbia’s EU ambitions and political reality
A general convicted of Europe’s first genocide since World War II was buried Monday with military and religious honors, sparking alarm in Brussels.
I thought I'd regret moving to Europe, but I'm happier than ever
Leah Young told Business Insider she has a better quality of life in France and can't imagine living in the US again.
Banijay Entertainment Unveils Ambitious Pan-European Lifestyle Format with Vinted
London, 24 August 2026: Media and entertainment group, Banijay Entertainment, today announces Live Better for Less, an ambitious new pan-European
EU chief unveils $232 million Greenland package
The European Union seeks to boost its relations with the vast island
Merz's day of reckoning after a devastating defeat in Saxony-Anhalt
The German chancellor seeks to reassure Europe that Germany’s institutions remain stable
Commission to present long-awaited Innovation Act proposal
The European Commission will present its proposal for an EU Innovation Act on September 9, with a focus on strengthening public procurement as a driver of innovation and facilitating the use of intellectual property (IP) to secure financing.The proposal was initially meant to be published in March. No explanation has been given for the delay, but it may be linked to issues with the associated impact assessment.The Commission’s Regulatory Scrutiny Board issued a negative opinion on the draft impact assessment following its meeting on January 28, and again on February 27, according to a draft of the Innovation Act published by Agence Europe.In it, the Commission lays out the steps it has taken to address the board’s concerns, including avoiding overlap with the upcoming revision of the EU Public Procurement Directives and removing a mandatory target for EU member states to increase overall innovation procurement spending.The Innovation Act, which was included in last year’s start-up and scale-up strategy, is meant to reduce barriers to bringing innovative solutions to the market and speed up the path from research to commercialisation.Central to the initiative, according to the draft proposal, is the introduction of a harmonised EU framework for the procurement of R&D services by public buyers, including pre-commercial procurement. The plans would also introduce an EU preference in public R&D procurement.“Other leading economies in the world are investing five to eight times more in public procurement of R&D than the EU,” it notes. In Europe, the lack of harmonised rules has led to divergent practices across the bloc, legal uncertainty and limited use of joint, cross-border R&D procurement, it says.Related articlesCommission postpones European Innovation ActParliament draft report adds EU Inc safeguards to prevent fraud and regime shoppingThe text highlights a lack of clarity around the valuation and monetisation of IP as another barrier to the commercialisation of research results. Currently in the EU, IP is rarely used as collateral in financing, which restricts the growth potential of innovative firms. A key reason for this, according to the Commission, is the absence of a harmonised methodology for valuing IP.To address this issue, it plans to introduce an EU-wide IP valuation framework, a digital marketplace for commercialising IP, and a competence centre to help innovators access IP-backed finance.The issue was highlighted by a recent report by the European Union Intellectual Property Office, which referred to developing a “functional market for IP-backed finance” as a “core competitiveness imperative for the next decade,” and key to ensuring capital unlocked by other EU initiatives reaches innovative firms.The Innovation Act is one of several ways the Commission hopes to reduce fragmentation in the single market and help innovative companies to scale in Europe, complementing other initiatives such as the EU-wide corporate regime, dubbed EU Inc.The leaked draft is not the final version that will be published on September 9, according to a Commission official.
Germany's far-right surge rattles Europe's political foundations
AfD's landslide win in Saxony-Anhalt could be the prelude to far-right forces governing alone across Europe. Germany's 'grand coalition' model, and the centrist alliance underpinning EU politics, are starting to crack.
DeAPlaneta to Represent Iron Maiden, Backstreet Boys in Europe
The company will serve as licensing agent for Global Merchandising Services' roster in Iberia, France and Central and Eastern Europe.
A German politician with a MAGA touch lifts his nationalist party to victory
Ulrich Siegmund and his Alternative for Germany party sent tremors through establishment political circles in Berlin, Brussels and other capitals across Europe.
On Clean Air Day, the EU Healthy Air Coalition is leading a call, joined by over 30 health organisations, for a fossil fuel phase-out to protect health
European and global health organisations call on EU leaders to swiftly phase out fossil fuels.
Europe's Top Performers: key statistics from the weekend
Along with all of the results from UEFA's 'Top 5' leagues, Playmaker is here to provide you with a rundown of the top performers.From the slickest passers enroute to the most tenacious tacklers via th...
Lenovo releases flagship Android tablet with 12,700mAh battery, Snapdragon 8 Elite and 4K display
Lenovo has released the Yoga Tab Plus Gen 2 in the US and several European markets. The high-end Android tablet features a 13-inch 4K 144Hz display, Snapdragon 8 Elite, a 12,700mAh battery, and bundled keyboard and pen accessories.
Mixed zone: Lille-Betis, with the roof closed 🏟️
Real Betis will play their next European fixture at the Pierre Mauroy Stadium under a closed roof, according to Zona Mixta. The adverse weather conditions forecast in Lille have forced a last-minute d...
Reaching knockout phase is bare minimum: Liverpool’s Champions League prospects
1xBet.ie highlights the key storylines of the European season for Liverpool fans. Watching LFC matches in the Champions League league phase will be even more exciting with the Welcome Bonus. All new u...
🥐 Barça romp, Diomande case... 5️⃣ stories to start Monday
FC Barcelona strengthened their grip on top spot after thrashing Valencia at Mestalla, while tension has taken over the Valencian club’s surroundings and Madrid are gearing up for their European deb...
Project aims to join up Europe’s ‘fragmented’ science advice
Coordinator of EU-funded initiative wants a “truly connected” science-for-policy ecosystem
Bacteria found in classroom dust may affect children’s respiratory health
Common bacteria found in classroom dust are associated with reduced lung function in children according to research presented at the European Respiratory Society (ERS) Congress in Barcelona, Spain.
Europe wants to build with Ukraine. Can its defence industry keep up?
As Kyiv pushes Europe to move faster, its defence industry is showing just how far behind the bloc still is
The science behind the beauty business
Some of Europe’s industrial champions may be in retreat, but its cosmetics sector remains a global leader, buoyed by healthy demand, recognised brands and a reputation for innovation."The fact is, the science in cosmetics is better here in Europe than anywhere else in the world,” says Pierre Morvan, CEO of Technature, a private label cosmetics manufacturer located near Brest in France’s northwestern Brittany region. “You have to have good science in order to make the difference, and that is why we invest so much in research and innovation.”Across Europe, the beauty and skincare products sector supports an estimated 3.6 million jobs, including 265,000 employed directly in the industry, according to the Cosmetics Europe trade group.. Cosmetics production contributes an estimated €11 billion to the EU economy, and generated €30 billion in export revenue last year, a €400 million rise from 2024.Technature itself has a global footprint, supplying products for 1,500 brands in 65 countries. Its range of skin gels, facial masks, nail treatments and other products include natural ingredients and extracts derived from plants, such as seaweed, that are developed and refined through science-based analysis and testing.While industry projections point to sustained growth for the foreseeable future, driven by emerging economies and wider availability of exclusive brands that were once chiefly sold by high street retailers, the sector is not immune to the impact of geopolitics and trade wars. The Trump Administration’s tariff threats have dented cosmetics exports to the EU industry's largest overseas market. After the European Parliament approved the EU-US Turnberry Agreement in June, setting a 15% levy on many EU goods, the French Federation of Beauty Companies warned that “exports are falling sharply” and urged the EU to negotiate an opt-out for cosmetics.Technature’s CEO flags South Korea as an emerging competitor, partly due to its assertive marketing efforts. “I would have to say I am a little bit scared,” Morvan says, regarding the growth potential of the South Korean cosmetics industry. “This is why science and innovation are so important if Europe is to remain the leader.”With a workforce of 200, including biologists, chemists and other scientists, around 15% of Technature’s staff work in three research and development (R&D) labs. A similar number work in four quality control and assurance facilities, where science plays a crucial in ensuring product safety in a sector that is subject to the European Cosmetics Regulation.Educational exchange between industry and academiaIn recognition of Technature’s research and innovation, Morvan was selected as one of Brest’s ambassadors to Science Comes to Town (SCTT), a European initiative to strengthen communications and understanding between science and society. Brest is one of three coastal cities in the EU-funded programme, alongside Split (in Croatia) and Kiel (in Germany). From 7-11 September, Brest will host the EU TalentOn contest featuring 100 early-career researchers from across Europe.Morvan appreciates the value of engagement with educational and scientific institutions as well as the home community. For instance, Technature collaborates closely with university partners to enhance its in-house R&D. In addition, it invites students to its labs and sends its own researchers to local institutions. "We absolutely want the students to know what the industry is all about,” Morvan says, noting that seeing science in action can help young people “understand that they can do something real with science, to create something with what they are learning.” He says another important benefit: encouraging new generations of young people to consider a career in cosmetics.Community involvement also raises awareness about Technature and the skincare industry as a whole. “The public gains recognition of the innovative company that we are, and this is important for getting new customers,” Morvan says. One of its recent innovations — tiny, colourful cosmetic pearls that release skin moisturisers on application — was showcased at this year’s VivaTech event in Paris.Morvan holds a master's degree from the Brest Business School and studied animal production and biology in Brest at the University of Western Brittany (UBO), an SCTT partner, and at the University of Tours. He got his start in business in 2002, initially working on using seaweed as a raw material in the food industry before transitioning to cosmetics. Morvan has always been interested in connecting science and business, reflecting one the goals of SCTT to enhance public-private collaboration.The invitation to participate in SCTT was unexpected. “It was a surprise to get a call from the city of Brest saying that they wanted me on this programme,” Morvan recalls, adding that officials were drawn by his company’s R&D. “It's not only theory and science fundamentals. Our science is something that is applicable to the global market — and important for the community.”Science|Business, which connects policymakers, academics and industry through its news reporting, analysis and events, is an SCTT partner.
AfD Victory in Saxony-Anhalt Sends a Signal to Europe
A vote in eastern Germany has given fresh momentum to hard-right parties hoping to win elections across Europe next year, analysts said.
It seems impossible not to mention Gaza if you meet Israelis on holiday in Europe
I made friends with two Israeli couples while on holiday in Greece this summer and when the conversation inevitably turned to Palestine, I was struck by how misinformed, scared, and ashamed they were.
Richard Ledezma, a key player for Guadalajara
Today the Red-and-White Nation is celebrating, as RichardLedezma was born on September 6, 2000, and this Sunday he turns 26.After building an impressive career in European soccer, ‘Richy’ arrived ...
TCL Reveals New Soundbar Range
Full specifications and pricing for the UK and other European countries now available, with all models set to go on sale before Christmas.
Keep the run going against Villarreal
This start to the season leaves you wanting more! And now, next Tuesday, Europe’s premier competition is finally back on the schedule at the most beautiful stadium in the world. A mix of sun and clo...
Europe's biggest arena braces for Celine Dion ticket scams
Celine Dion fans are facing ticket scams as they flock to Paris for her comeback shows. The Plenitude Arena, hosting 26 concerts, warns of scammers exploiting high demand.
From the Treasure of Villena to the French Crown Jewels: The lucrative business of stealing pieces of history
The spectacular rise in the price of gold over the past nine years has triggered a wave of increasingly violent heists at European museums, which are struggling to protect themselves