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Menopause Legislation and Hearing Highlights

Recent menopause legislation and hearing emphasize the scale of the issue, plus a bipartisan focus on research, health care, and public health.

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Oct 26 • 10:00 AM EDT • Health • astho.org
Intermountain Health wants women to prioritize mammograms with simplified online scheduling

Thanks to recent upgrades at Intermountain Health, it's easy for women to schedule an appointment for their annual screening mammogram.

ksl.com logo
Oct 26 • 10:00 AM EDT • Health • ksl.com
Trump and Vance accelerate downward political spiral

Senior political analyst Juan Williams criticizes several candidates in the 2026 midterm elections for employing increasingly unethical and deceptive political advertising tactics.

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Oct 26 • 9:30 AM EDT • Politics • thehill.com
The Texans struggle defensively again in 27-21 overtime loss to Giants

Missed tackles, wide-open receivers and big play after big play led to a 27-21 overtime loss to the New York Giants on Sunday that dropped Houston to 2-5.

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Oct 26 • 9:25 AM EDT • Sports • spectrumlocalnews.com
OU receives more than $5M for maternal health research

OU’s College of Nursing secured more than $5 million in new NIH funding for four maternal health research projects over four years.

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Oct 26 • 9:00 AM EDT • Health • journalrecord.com
Suki Secures $90 Million | Confido Health Expands Agentic Operating Platform

Check out today's featured companies who have recently raised a round of funding, and be sure to check out the full list of past healthcare IT fundings.

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Oct 26 • 9:00 AM EDT • Health • healthcareittoday.com
SBA disaster loans available to business, private nonprofits impacted by drought

The U.S. Small Business Administration (SBA) recently announced the availability of low-interest federal disaster loans for eligible Wisconsin small businesses and private nonprofit organizations impacted by drought that began on Tuesday, Aug. 18.

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Oct 26 • 8:51 AM EDT • Business • tomahawkleader.com
Barack Obama calls for basic decency in politics at Ohio rally

Former President Barack Obama campaigns in Ohio, warning against political divisiveness and calling for basic decency. The panel discusses the impact of his message on key midterm races in the heartland.

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Oct 26 • 8:10 AM EDT • Politics • foxbusiness.com
Financial Woes Looms Over Washington's Revenue Sports

With Washington basketball's season set to tip off in just a few days, the second of the Huskies' two revenue sports finds itself in a very similar predicament to the football team. According to a recent report from CBS surveying the roster spending of college basketball programs across the nation, Danny Sprinkle's program ranked last in the Big Ten, spending approximately $5-7 million in NIL on its players.

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Oct 26 • 8:01 AM EDT • Sports • thenewstribune.com
UN climate science body left in limbo without budget sign-off after deadlock

Stranglehold on funding for the IPCC follows push from fossil fuel-reliant nations to delay publication of global warming reports

ft.com logo
Oct 26 • 8:00 AM EDT • Science • ft.com
Who’s spending money on the California insurance commissioner race

Jane Kim and Ben Allen have promised not to take insurance money, but an outside PAC supporting Allen has received industry donations.

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Oct 26 • 8:00 AM EDT • Politics • calmatters.org
Partner1 Renews WBENC Women's Business Enterprise and Women-Owned Small Business Certifications

Recertification caps a year in which founder and CEO Juhi Saha was named to Inc.’s 2026 Female Founders 500 and Partner1 was named an Inc. Power Partner for the second year runningPLEASANTVILLE, N.Y., Oct. 26, 2026 (GLOBE NEWSWIRE) -- Partner1, the advisory firm and software platform behind the partnership strategies of fast-growing B2B software companies, today announced it has renewed its Women’s Business Enterprise (WBE) and Women-Owned Small Business (WOSB) certifications from the Women’s Bu

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Oct 26 • 7:42 AM EDT • Business • finance.yahoo.com
Protesters Storm Rome’s Colosseum as Political Unrest Surges

Demonstrators forced their way inside Rome’s Colosseum on Saturday amid political and economic unrest that has rocked Europe in recent days. NBC’s Raf Sanchez reports for TODAY.

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Oct 26 • 7:32 AM EDT • Politics • today.com
The Daily Mauling: 10/26/26

Kansas Jayhawks News The LJW talks about KU’s exhibition loss to Duke, with a focus on Bill Self’s small ball lineups UNLV coach Josh Pastner is whining about having to play Trey Kaufman-Renn when the Rebels visit Lawrence. Interesting complaints for a guy who went out and got AJ Storr this offseason SI also brings […]

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Oct 26 • 7:03 AM EDT • Sports • sports.yahoo.com
Georgia Opens as Overwhelming Favorites vs. Florida

Despite the Gators' momentum and Georgia’s recent stumble against Auburn, oddsmakers have the Bulldogs as double-digit favorites.

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Oct 26 • 7:00 AM EDT • Sports • sports.yahoo.com
Pioneering rock frontman dead at 72: ‘A titan amongst men’

His body was discovered in his home by his niece.

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Oct 26 • 7:00 AM EDT • Entertainment • nj.com
Are these NFL teams actually good? Plus, a gruesome NBA injury

The Pulse Newsletter 📣 | This is The Athletic’s daily sports newsletter. Sign up here to receive The Pulse directly in your inbox. Good morning! Score 50 points today. Coming up: 🏈 A wild Week 7 💔 Williams carted off 🎠 Coaching carousel in full swing There is still so, so much time left in the NFL season. But after another baffling batch of games yesterday, I could not resist simply looking at the division standings and cackling at our current reality. Are some of these teams actually good? Are the teams we thought were good actually just OK? Do we know anything? ...

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Oct 26 • 6:25 AM EDT • Sports • nytimes.com
Did a health insurance contract lapse under Crowley's administration?

A health insurance contract covering Milwaukee County employees lapsed in December under County Executive David Crowley

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Oct 26 • 6:06 AM EDT • Health • jsonline.com
2 Kentucky Wildcats make CBS Sports’ preseason top 101 College Basketball players list

Which Kentucky Wildcats received some love from CBS Sports ahead of the 2026-27 season?

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Oct 26 • 6:05 AM EDT • Sports • sports.yahoo.com
Why Justin Champagnie Is Earning Permanent Role in Wizards Rotation

The Washington Wizards are working through its rotation, but Justin Champagnie has made clear why he's an impact piece even with more competition

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Oct 26 • 6:00 AM EDT • Sports • sports.yahoo.com
‘Astronomical’ Arab turnout could reshape Israeli politics in key election

Netanyahu’s opponents consider unprecedented alliances to keep him out of power

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Oct 26 • 5:58 AM EDT • Politics • thenationalnews.com
Analysis | Saddam’s Cheesecake Factory: Trump’s predecessors go after him in ways only they can

In today’s edition … Voters are changing their minds … You tell me about your first time voting … but first …

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Oct 26 • 5:24 AM EDT • Politics • washingtonpost.com
Unlocking the mystery behind election polling

Political polling has been a staple of election season for hundreds of years. But recently, a lot of polls have missed the mark — widely. We take a look at how polling is done in Florida.

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Oct 26 • 5:05 AM EDT • Politics • wusf.org
Nebraska receives no votes in AP Top 25

The Nebraska Cornhuskers received no votes in this week's AP Top 25 Poll.

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Oct 26 • 4:04 AM EDT • Sports • sports.yahoo.com
🙂 Positive (50%)
Augusta Mall coffeeshop barely makes a B grade: Health Scores

A coffeeshop in the Augusta Mall just barely scored a B on recent restaurant inspections. Find out why.

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Oct 26 • 4:01 AM EDT • Health • yahoo.com
Seahawks Jaxon Smith-Njigba Delivers Simple Message After Beating Chiefs

Seattle Seahawks wide receiver Jaxon Smith-Njigba had a simple message after his team beat the Kansas City Chiefs. The post Seahawks Jaxon Smith-Njigba Delivers Simple Message After Beating Chiefs appeared first on HEAVY.

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Oct 26 • 3:34 AM EDT • Sports • sports.yahoo.com
Guest article: Health data is booming. Meaningful insights? Not so much

The growth of wearables means we're awash with data, but not necessarily great insight, says Cornucopian Capital managing partner Aryeh Ganz.

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Oct 26 • 3:00 AM EDT • Health • agfundernews.com
Business News: Audemars Piguet Unveils 'The Watch Keepers' - A Digital Platform Offering Certified Pre-Owned Watches

The Le Brassus watchmaker will facilitate sales and auctions of brand-certified timepieces on a digital platform launching in Switzerland and Europe, with plans for expansion to other markets, including the U.S.

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Oct 26 • 3:00 AM EDT • Business • hodinkee.com
‘Been a Problem for a Very, Very Long Time’ — Revisiting the Time Fox’s Pam Oliver Revealed the Health Battle That Impacts Her Sideline Reporting

NFL sideline reporter Pam Oliver has been a fixture in the business for more than 30 years, covering the league for Fox. At 65, she’s also one of the most experienced voices on the sidelines, most recently covering the San Francisco 49ers’ Week 7 matchup against the Atlanta Falcons.

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Oct 26 • 2:43 AM EDT • Health • sports.yahoo.com
Aaron Gordon Praises David Adelman's New System

Aaron Gordon is the perfect piece for David Adelman's new system.

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Oct 26 • 2:34 AM EDT • Sports • sports.yahoo.com
KC has no answers for Jaxon Smith-Njigba on SNF

Jaxon Smith-Njigba led all players in targets, receptions, and total yards as part of a dominant effort versus the Kansas City Chiefs in Week 7.

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Oct 26 • 2:27 AM EDT • Sports • sports.yahoo.com
Chiefs Announce Historic Travis Kelce News During Seahawks Game

Kansas City Chiefs tight end Travis Kelce can’t stop making NFL history.With his third reception in the fourth quarter against the Seattle Seahawks on Sunday night, Kelce has passed Hall of Famer Tony Gonzalez for the most receiving yards by a tight end ever, including the postseason, with 13,342.Kansas City Chiefs’ Travis Kelce is Most […] The post Chiefs Announce Historic Travis Kelce News During Seahawks Game appeared first on HEAVY.

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Oct 26 • 1:46 AM EDT • Sports • sports.yahoo.com
Franciscan Health receives stuffed animals for pediatric patients across Northwest Indiana

NORTHWEST INDIANA — Pediatric patients in Franciscan Health emergency rooms, pediatric inpatient units and outpatient surgery centers in Michigan City, Chesterton, LaPorte, Dyer and Munster will now have stuffed animals to help make their hospital experience a little more comfortable, thanks to a donation by The Eva Martin Project. Representatives from The Eva Martin Project recently donated more than 1,400 new stuffed animals to the nonprofit Catholic healthcare system during a drop-off at Franciscan Health Michigan City. Each item has a tag with the organization’s logo and a QR code with a personal message on the back. The nonprofit organization

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Oct 26 • 1:10 AM EDT • Health • wimsradio.com
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Lorna Goodison wins 2026 Derek Walcott Prize for Poetry

Celebrated Jamaican poet Lorna Goodison has added another prestigious international honour to an already distinguished literary career, winning the 2026 Derek Walcott Prize for Poetry for her ground-breaking new translation of the 14th-century classic, Dante’s Inferno. Goodison, Jamaica’s first female Poet Laureate, serving from 2017 to 2020, receives the US$2,000 prize for a work that boldly transports Dante’s epic journey into a Caribbean landscape, drawing deeply on Jamaican language, culture, history and identity.

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Oct 26 • 1:06 AM EDT • Entertainment • jamaica-gleaner.com
‘Resident Evil’ film resurrects horror game franchise

The first “Resident Evil” game came out in 1996, and since then, the franchise has been working to bring zombies, creatures and deadly outbreaks to life. For the newest piece,

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Oct 26 • 1:00 AM EDT • Entertainment • valpotorch.com
The Rise of Independent Voters Is Reshaping American Politics

In this Fulcrum Roundtable discussion, Jeremy Gruber of Open Primaries explains why voters are leaving the major parties, how closed primaries limit participation, and what reforms could expand representation for nearly half the country.

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Oct 26 • 12:40 AM EDT • Politics • thefulcrum.us
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Norman Silverman to Open First Flagship Store in Beverly Hills

Los Angeles diamond jeweler Norman Silverman is opening its first flagship store at The Maybourne Beverly Hills in December.

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Oct 26 • 12:01 AM EDT • Business • wwd.com
US has plans for major Iran strikes if Trump chooses

US forces in the Middle East are prepared to launch new, potentially major, military operations against Iran “within 96 hours of receiving” an order from President Donald Trump, according to two US officials.

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Oct 26 • 12:00 AM EDT • Politics • cnn.com
Jaylen Waddle totals four receptions in Week 7

Denver Broncos wide receiver Jaylen Waddle posted four receptions for 48 yards on a team-high seven targets in Week 7

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Oct 25 • 11:57 PM EDT • Sports • sports.yahoo.com
Trey McBride piles up 10 receptions in loss to Denver

Arizona Cardinals TE Trey McBride busy in Week 7 loss to Broncos

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Oct 25 • 11:51 PM EDT • Sports • sports.yahoo.com
Jacoby Brissett throws for 272 yards in Week 7

Arizona Cardinals QB Jacoby Brissett finishes posts decent numbers in Week 7 loss to Denver

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Oct 25 • 11:23 PM EDT • Sports • sports.yahoo.com
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🎥 Drama galore as LAFC and Galaxy finish level

There were major fireworks in Los Angeles as the city's two bitter rivals, LAFC and LA Galaxy finished level in a crucial MLS showdown. The Galaxy had a two-goal lead in the second half and looked w...

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Oct 25 • 11:20 PM EDT • Sports • sports.yahoo.com
How to talk politics with family: Minnesota debate coach shares tips

A University of Minnesota debate coach is sharing advice on navigating political disagreements ahead of Election Day. He explains winning the argument isn't necessarily the goal of a political debate.

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Oct 25 • 11:10 PM EDT • Politics • yahoo.com
How to talk politics with family: Minnesota debate coach shares tips

A University of Minnesota debate coach is sharing advice on navigating political disagreements ahead of Election Day. He explains winning the argument isn't necessarily the goal of a political debate.

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Oct 25 • 11:10 PM EDT • Politics • fox9.com
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Rashid Shaheed leaves Week 7 with knee injury

Seattle Seahawks wide receiver Rashid Shaheed posted two receptions for just one yard on three targets in Week 7

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Oct 25 • 11:03 PM EDT • Sports • sports.yahoo.com
Ashton Jeanty catches TD in Week 7 loss

Las Vegas Raiders RB Ashton Jeanty has busy day as a receiver against Rams in Week 7

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Oct 25 • 10:40 PM EDT • Sports • sports.yahoo.com
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Bruins’ Unbeaten Run Gets A Bigger Test Against The Hurricanes

Boston keeps finding ways to survive difficult moments, but the Bruins’ latest comeback sets up a tougher question: can they carry that resilience into a Tuesday road game against one of the NHL’s most demanding opponents?

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Oct 25 • 10:14 PM EDT • Sports • sports.yahoo.com
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Arkansan visits Washington, supports push to improve female veterans’ healthcare

WASHINGTON -- An Arkansas veteran was part of a recent push urging Congress to consider legislation to improve healthcare for women veterans.

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Oct 25 • 10:00 PM EDT • Health • arkansasonline.com
Jaylin Noel dealing with turf toe injury

Houston Texans wide receiver Jaylin Noel suffered a turf toe injury in the Week 7

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Oct 25 • 9:51 PM EDT • Sports • sports.yahoo.com
Tucker Kraft scores TD in Week 7 vs. Lions

Green Bay Packers tight end Tucker Kraft finished with four receptions for 48 yards and a touchdown on six targets in Week 7

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Oct 25 • 9:34 PM EDT • Sports • sports.yahoo.com
😐 Neutral (0%)
Celtics’ Joe Mazzulla Addresses Growing Tatum-Brown Tension

For years, Boston Celtics fans have wondered whether Jayson Tatum and Jaylen Brown were friends off the basketball court. Following Brown’s recent comments to the media, it’s become clear that even if they were, that isn’t the case anymore.On Sunday, October 25, Celtics’ head coach Joe Mazzulla was asked about Brown’s recent comments regarding Tatum […] The post Celtics’ Joe Mazzulla Addresses Growing Tatum-Brown Tension appeared first on HEAVY.

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Oct 25 • 9:28 PM EDT • Sports • sports.yahoo.com
Windows 11’s new “better performance” toggle shows up, but your current PC will never be able to use it

Windows 11's recent preview builds include a new toggle called "Advanced Performance Extensions," aka "APX," and on supported hardware.

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Oct 25 • 8:15 PM EDT • Technology • windowslatest.com
Johnson County Focus on Youth Fund promotes access to children’s mental health resources

This is an installment of a series exploring youth mental health. The Daily Iowan has received a grant and is partnering with the Solutions Journalism Network to explore the topic. The Johnson County Focus on Youth Fund has been promoting access to children’s mental health resources by providing funding for families who can’t afford services....

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Oct 25 • 8:13 PM EDT • Health • dailyiowan.com
Wan'Dale Robinson held to seven yards in Week 7

Tennessee Titans wide receiver Wan'Dale Robinson posted four receptions for just seven yards in Week 7

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Oct 25 • 8:06 PM EDT • Sports • sports.yahoo.com
UCLA Library's Data Science Center closed amid consolidation effort

UCLA Library dissolved its data consultation center and stopped offering data analysis services in August. The university consolidated the Data Science Center into UCLA Library’s research services unit as part of a broader effort to restructure the department, a UCLA Library spokesperson said in an emailed statement.

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Oct 25 • 8:00 PM EDT • Science • dailybruin.com
Australian politicians pay tribute to wounded lawmaker

Australia's prime minister and fellow parliamentarians led sombre tributes Monday to "beacon of decency" and colleague Helen Haines, who remains in hospital after being struck by a car outside her off...

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Oct 25 • 7:40 PM EDT • Politics • yahoo.com
Teddy Roosevelt Erred on Neanderthals

Just recently, paleontologists have found Neanderthal wooden tools (62-40 kya) preserved in stone.

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Oct 25 • 7:28 PM EDT • Science • scienceandculture.com
Health network adding helicopter in rapid Pennsylvania expansion

WESTMORELAND COUNTY, Pa. (WHTM) — Not long after they acquired five Pennsylvania hospitals, a health system will soon launch an air medical helicopter in the Keystone State. WVU Health System recently...

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Oct 25 • 7:15 PM EDT • Health • yahoo.com
Denzel Boston quiet in Week 7 road win vs. Titans

Cleveland Browns wide receiver Denzel Boston registered three receptions for 27 yards on eight targets in Week 7

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Oct 25 • 7:07 PM EDT • Sports • sports.yahoo.com
🙂 Positive (40%)
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Chiefs vs. Seahawks live updates, inactives, where to watch: Kenneth Walker III faces Seattle for first time since Super Bowl MVP run
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Oct 25 • 7:01 PM EDT • Sports • sports.yahoo.com
Xbox console users will receive 50 games from October 26 to 31.

From October 26th to 31st, the Xbox ecosystem and Xbox PC service will receive a major expansion of their catalog, including the release of 50 new games for...

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Oct 25 • 6:40 PM EDT • Technology • en.gamegpu.com
Stephen Curry set to return Monday for struggling Warriors

Stephen Curry set to return Monday for struggling Warriors

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Oct 25 • 6:38 PM EDT • Sports • sports.yahoo.com
Isaiah Likely disappoints in Week 7 vs. Texans

New York Giants tight end Isaiah Likely limited to two receptions for 12 yards on four targets in Week 7

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Oct 25 • 6:32 PM EDT • Sports • sports.yahoo.com
Pirates Should Re-Sign This Upcoming Free Agent

Gregory Soto could still be a solid piece in the Pittsburgh Pirates bullpen in 2027.

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Oct 25 • 6:20 PM EDT • Sports • sports.yahoo.com
Raptors to miss Kawhi Leonard on Sunday night

The Raptors will be without a key piece of their lineup on Sunday night.

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Oct 25 • 6:11 PM EDT • Sports • sports.yahoo.com
😐 Neutral (0%)
Jaylin Noel goes backward in Week 7 vs. Giants

Houston Texans wide receiver Jaylin Noel posted two receptions for minus-3 yards on two targets in Week 7

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Oct 25 • 6:04 PM EDT • Sports • sports.yahoo.com
😐 Neutral (0%)
The Next FRIDAY THE 13TH Movie Can Finally Fix An Infamous Mistake

We don’t know precisely when, but a new Friday the 13th movie is coming. After a 17-year drought, the franchise has come back to life, most recently with the release of Crystal Lake on Peacock, a show...

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Oct 25 • 6:00 PM EDT • Entertainment • yahoo.com
Marvin Harrison Jr. scores TD vs. Giants in Week 7

Houston Texans wide receiver Marvin Harrison Jr. posted a single 6-yard reception for a touchdown on four targets in Week 7

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Oct 25 • 5:57 PM EDT • Sports • sports.yahoo.com
Nico Collins disappoints in Week 7 vs. Giants

Houston Texans wide receiver Nico Collins posted two receptions for six yards on five targets in Week 7

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Oct 25 • 5:50 PM EDT • Sports • sports.yahoo.com
Dalton Schultz totals five receptions in Week 7

Houston Texans tight end Dalton Schultz posted team highs with five receptions, 45 yards and six targets in Week 7

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Oct 25 • 5:43 PM EDT • Sports • sports.yahoo.com
C.J. Stroud tosses two TDs in Week 7

Houston Texans quarterback C.J. Stroud completed 17 of 28 passes for 153 yards, two touchdowns and no interceptions in Week 7

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Oct 25 • 5:15 PM EDT • Sports • sports.yahoo.com
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Chuba Hubbard has decent outing in Week 7

Panthers RB Chuba Hubbard finishes with 33 rushing yards and 27 receiving yards

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Oct 25 • 4:53 PM EDT • Sports • sports.yahoo.com
T.J. Hockenson finds end zone in Week 7 vs. Colts

Minnesota Vikings tight end T.J. Hockenson posted four receptions for 35 yards and a touchdown on five targets in Week 7

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Oct 25 • 4:51 PM EDT • Sports • sports.yahoo.com
Justin Jefferson limited to 44 yards in Week 7

Minnesota Vikings wide receiver Justin Jefferson had four receptions for a team-high 44 yards on seven targets in Week 7

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Oct 25 • 4:38 PM EDT • Sports • sports.yahoo.com
☹️ Negative (-7%)
Four receptions for Chris Godwin Jr.

Buccaneers WR Chris Godwin Jr. leads team with four receptions in Week 7 win

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Oct 25 • 4:31 PM EDT • Sports • sports.yahoo.com
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Cleveland Browns rookie WR hits historic mark against Titans

KC Concepcion’s 129 receiving yards places him in the Top 10 for a single game by a rookie in franchise history.

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Oct 25 • 4:22 PM EDT • Sports • sports.yahoo.com
😐 Neutral (0%)
Bengals blank Ravens in second half, win 35-13
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Oct 25 • 4:01 PM EDT • Sports • sports.yahoo.com
Puka Nacua active for Week 7 vs. Raiders

Los Angeles Rams wide receiver Puka Nacua is active for the Week 7 game

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Oct 25 • 3:05 PM EDT • Sports • sports.yahoo.com
Kaine, Randall tour county's new Crisis Receiving and Stabilization Center

The Loudoun County Crisis Receiving and Stabilization Center's first day of operations on Oct. 22 included a tour by Sen. Tim Kaine, D-Va., and county Board of Supervisors Phyllis J.

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Oct 25 • 3:00 PM EDT • Health • loudountimes.com
Three receptions for Germie Bernard

Steelers WR Germie Bernard catches three of his five targets in Week 7 win

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Oct 25 • 1:40 PM EDT • Sports • sports.yahoo.com
Chris Olave targeted 10 times in Week 7

New Orleans wide receiver Chris Olave went for six receptions for 56 yards on 10 targets in Week 7

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Oct 25 • 1:33 PM EDT • Sports • sports.yahoo.com
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Nico Williams publicly disavows his agent over Barcelona transfer claims

Barcelona’s long and drawn-out pursuit of Nico Williams has become one of the more familiar sagas of recent transfer windows.The Athletic Club winger ultimately opted to stay at San Mames, snubbing ...

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Oct 25 • 1:17 PM EDT • Sports • sports.yahoo.com
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Clatsop County health inspections for September

Clatsop County health inspectors recently completed a round of restaurant inspections that yielded overwhelmingly positive results for most local eateries. But one Seaside establishment received a temporary closure after receiving […]

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Oct 25 • 1:10 PM EDT • Health • dailyastorian.com
Lakers 1st-Round Draft Pick Floated as Trade Piece

The Los Angeles Lakers are off to a fast start. Could it be time to weigh trading away some young pieces to boost the rotation? The post Lakers 1st-Round Draft Pick Floated as Trade Piece appeared first on HEAVY.

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Oct 25 • 12:29 PM EDT • Sports • sports.yahoo.com
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Buccaneers vs. Panthers Week 7 inactives: Baker Mayfield returns

The Tampa Bay Buccaneers are set to take on the Carolina Panthers Sunday afternoon in a crucial NFC South matchup at Bank of America Stadium in Charlotte. Tampa Bay received some encouraging news ahead of kickoff as quarterback Baker Mayfield is officially active and will start after missing the previous three games with a dislocated […]

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Oct 25 • 12:05 PM EDT • Sports • sports.yahoo.com
😐 Neutral (0%)
Connections: Law firms hire attorneys for NWA offices

Two Little Rock-based law firms have hired attorneys for their Northwest Arkansas offices, and the Single Parent Scholarship Fund of Northwest Arkansas recently announced new board members. NEW HIRES Banking...

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Oct 25 • 11:50 AM EDT • Politics • talkbusiness.net
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Connections: Law firms hire attorneys for NWA offices

Two Little Rock-based law firms have hired attorneys for their Northwest Arkansas offices, and the Single Parent Scholarship Fund of Northwest Arkansas recently announced new board members. NEW HIRES Banking...

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Oct 25 • 11:50 AM EDT • Business • talkbusiness.net
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ESMO: Roche touts ‘convincing’ phase 3 KRAS data after win over rivals

Roche has shed more light on its investigational KRAS G12C inhibitor's phase 3 victory over Amgen’s Lumakras and Bristol Myers Squibb’s Krazati. The open-label Krascendo 1 trial enrolled 338 people with previously treated KRAS G12C-mutated non-small cell lung cancer (NSCLC). Patients who had already received a KRAS G12C inhibitor or pan-KRAS/RAS inhibitor were excluded from the trial. Participants received either divarasib once daily, Lumakras once daily or Krazati twice daily. Roche announced back in July that divarasib had demonstrated statistically significant improvements in progression-free survival (PFS) and overall survival (OS), meeting the trial’s primary and key secondary endpoints. But the Swiss pharma had been holding back the detailed data until now. At the European Society for Medical Oncology (ESMO) Congress in Madrid, Roche revealed that median OS for the 167 patients who received divarasib was 17.7 months, compared to 12 months for the 171 patients who received Lumakras or Krazati. The benefit was similarly clear when it came to median PFS, which stood at 9.8 months versus 5.7 months, respectively. A total of 44% of patients receiving divarasib were alive without disease progression at one year, compared to 24% of the control group, according to Roche’s presentation. It was a similar story for the objective response rate, which came in at 58% for divarasib versus 32% for the control group, while median duration of response was 11.9 months versus 6.9 months. Stefan Frings, M.D., Ph.D., deputy chief medical officer at Roche Pharma, told Fierce that the data made for a “very comprehensive, strong package, which should be convincing to health authorities.” “It’s an important advance for patients with lung cancer,” Frings said in an interview at a Madrid hotel during the conference. “It's a second-line setting, and patients who receive divarasib benefit compared to the current first-generation KRAS G12C inhibitors by having far longer overall survival,” he continued. “They live longer. They have better progression-free survival, better response rates, and with a safety profile which is—if [anything]—even better,” he said. According to Roche, 4.8% of patients receiving divarasib discontinued treatment due to treatment-related adverse events, compared to 11.7% in the control group. Serious treatment-related adverse events were also less common with divarasib, at 7.8% versus 15.2%. Roche’s confidence in divarasib had been building even before this phase 3 success. The candidate had already shown better potency and selectivity than the incumbent KRAS G12C inhibitors Krazati and Lumakras in preclinical tests. After cross-trial comparisons suggested that the edge translated into better clinical outcomes, Roche axed a study comparing divarasib to the chemotherapy docetaxel and went toe-to-toe with Lumakras and Krazati. “We designed the drug on purpose with higher potency and better selectivity,” Frings explained. “So, based on preclinical models, we clearly knew it would be superior to the first generation.” “It’s honestly not so frequent that pharma companies go head-to-head,” he added. “But if you want to make a point, if you want to convince payers, prescribers and patients … then a head-to-head win is rather rewarding.” While Amgen and BMS reached the regulatory finish line first for KRAS G12C-mutated, locally advanced or metastatic NSCLC in 2021 and 2022, respectively, they have struggled to capitalize on their head start. Krazati brought in $55 million for BMS in the second quarter, while Lumakras delivered $111 million to Amgen. For its part, Roche is aiming for peak divarasib sales of 1 billion to 2 billion Swiss francs ($1.2 billion to $2.5 billion), according to Frings. The Big Pharma is currently recruiting patients into a phase 3 trial comparing divarasib plus Keytruda against Keytruda plus chemotherapy in previously untreated advanced or metastatic nonsquamous KRAS G12C-mutated NSCLC. Roche has previously suggested that sales in metastatic disease would account for most of the forecast. Frings was tight-lipped on the exact timeline for a regulatory filing but said the Swiss pharma is “certainly keen to get this to as many patients as possible around the world.” Roche has more RAS drugs coming up behind divarasib. The pharma has already launched phase 1 trials of a pan-RAS inhibitor called RG6505 and a KRAS G12D inhibitor dubbed RG6620 in solid tumors. Roche’s partner Chugai Pharmaceutical is also testing a pan-KRAS inhibitor called AUBE00. Roche has made a “deliberate effort” to test a range of RAS drugs, Frings said. “If you have many rare mutations and you are scrambling to find sufficient patients, a pan-RAS inhibitor makes a lot of sense,” he explained.

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Oct 25 • 11:30 AM EDT • Health • fiercebiotech.com
Nonprofit organizes ‘silkies’ hike to support military members’ mental health

Veterans, active military service members and community supporters recently gathered for a hike organized by a nonprofit dedicated to suicide prevention.

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Oct 25 • 11:27 AM EDT • Health • wpxi.com
Senator, former California Secretary of State Alex Padilla weighs in on voter roll fight

With one week left before the midterm elections, California is facing a federal lawsuit alleging that non-citizens were registered to vote, received mail-in ballots, and, in some cases, voted.

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Oct 25 • 11:25 AM EDT • Politics • kcra.com
Rumored Lucia Actress Goes Viral After Dodging Swarm of GTA 6 Comments During Livestream

Manni L. Perez, the actress long rumored to be playing Lucia in GTA 6, has gone viral after dodging a swarm of comments from Grand Theft Auto fans during a recent livestream.

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Oct 25 • 11:14 AM EDT • Technology • ign.com
Wrexham’s Summer Striker Decision Faces Fresh Scrutiny After Blackburn Defeat

Wrexham’s decision to back their current centre-forwards has become a renewed talking point after Saturday’s 2–0 defeat at Blackburn Rovers exposed the gap between attacking activity and a meaningful goal threat.

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Oct 25 • 11:00 AM EDT • Sports • sports.yahoo.com
University of Rochester Medicine Home Healthcare holds inaugural Hospice 5K

13WHAM ABC Rochester provides local news, weather forecasts, traffic updates, health reports, notices of events and items of interest in the community, local sports and entertainment programming for Rochester and nearby towns and communities including Greece, Victor, Pittsford, Penfield, Henrietta, Webster, Irondequoit, Fairport, Chili, Gates, Rush, Wheatland, Canandaigua, Farmington, Spencerport and Hilton.

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Oct 25 • 10:44 AM EDT • Health • 13wham.com
Obama, in Midwest, assails 'cruelty' and indecency from Trump and his allies in the midterm campaign

Obama remains the Democratic Party’s best motivator nearly a decade after leaving the White House. And he's taking his star power on the road in the final days of the midterm elections, which will help determine the balance of power in American politics on Nov. 3.

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Oct 25 • 10:35 AM EDT • Politics • pbs.org
LETTER TO THE EDITOR: Misleading political mailer is a smear campaign

The recent misleading smear mailer by the opponents of Denise Krause in the Oregon Senate campaign is the most disgusting exhibit of money and indecency used to capture uninformed voters’ […]

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Oct 25 • 10:00 AM EDT • Politics • rv-times.com
Manchester United vs Bournemouth: Live updates from Old Trafford

Under-fire Manchester United manager Michael Carrick is under enormous pressure heading into today’s Premier League clash with Bournemouth on the back of a seven-game run without a win.The boss has ...

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Oct 25 • 10:00 AM EDT • Sports • sports.yahoo.com
Science Snapshots: October 25, 2026

Three key science updates in one minute: Starry Night’s dawn matched to Jul 22, 1889; cold boosts lifespan via BH2/BH4; cluster similar-buildings cools cities.

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Oct 25 • 9:40 AM EDT • Science • thehindu.com
Indiana football should be better. It also could be worse

On one hand, Indiana hasn’t played its best football in weeks. On the other, neither has anyone else, really.

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Oct 25 • 9:06 AM EDT • Sports • sports.yahoo.com
One Underrated Timberwolves Wing Gets High Praise From Chris Finch

Terrence Shannon Jr. is shaping up to be one of the Timberwolves' sneakiest threats.

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Oct 25 • 9:00 AM EDT • Sports • sports.yahoo.com
Local breakfast chain plans Derby expansion

The Easy Egg, a Wichita-based breakfast and lunch restaurant, recently announced plans to expand into Derby. Reports indicate the local chain will take over the space at 317 N. Rock

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Oct 25 • 8:35 AM EDT • Business • derbyinformer.com