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Kathy Griffin jokes Barron Trump sends her notes pleading, ‘Don’t kill my daddy’
Kathy Griffin looks back on her Donald Trump photo scandal, joking to EW that Barron Trump sends her notes saying, ‘Don’t kill my daddy.’
ERDC brings science out of the lab with new event
Inaugural Vicksburg Science on Tap will give the public a casual look at research taking place at ERDC.
BGI Genomics Launches "Digital Life Twin" Framework to Power Proactive Health
Commemorating BGI Group's 27th anniversary, BGI Genomics today introduced its Digital Life Twin framework alongside an advanced multi-omics diagnostic portfolio at the 2026 Global New Product Launch Event. Grounded in over two decades of population-scale genetic discoveries, the launch marks a decisive transition from traditional, reactive diagnostics to continuous, predictive health management across the entire human lifecycle.
Can Ohio business leaders shift data center opinions? Business leaders hope so
Ohio business leaders are launching a campaign to counter what they see as data center misinformation and convince skeptical communities that the facilities can be good neighbors.
The Business of Building a Medical Practice
In this episode of Entrepreneurial Shades of Gray, Dani sits down with Dr. William Boyd, who has spent more than 30 years building and running his own practices.
Ubisoft joins Xbox's disc-to-digital program, with more publishers to follow
Some outlets were highlighting Ubisoft's lack of involvement in Xbox's disc-to-digital program. Perhaps we should remind ourselves that it's still in Alpha testing.
Three-time MVP Aaron Judge returns to Yankees
BRONX, N.Y. (WIVT/WBGH) – Sticking with the diamond, let’s move up to the major leagues where the Yankees are set to welcome back the captain tonight. Aaron Judge is making his return in the pinstripes tonight. No. 99 ironically had a 99-day absence after he suffered a broken rib. The three-time AL MVP missed 84 […]
Gault Toyota Athlete of the Week is back
SOUTHERN TIER, N.Y. (WIVT/WBGH) – With high school sports back in season, we at News 34 are bringing back the Gault Toyota Athlete of the Week. Any high school athlete can be nominated, regardless of sport. We will send out polls on our website where you can vote for the Athlete of the Week from […]
Business district battle in Back Bay Power Play
Back Bay's biggest landlord steps up its fight against a business improvement district for the neighborhood.
AZ's R&D chief Barr touts internal 'science success story' after IL-33 antibody's stellar showing in COPD
With a detailed data drop that AstraZeneca’s R&D chief described as an internal “science success story,” the British Big Pharma has secured an FDA priority review for what it believes could become a flagship biologic in chronic obstructive pulmonary disease (COPD). In detailed results from the late-stage Oberon and Titania trials—first teased in March and detailed in full at the European Respiratory Society Congress in Barcelona this week—the drugmaker laid out the extent of its IL-33 inhibitor’s potential to reduce moderate and severe exacerbations in a wide range of COPD patients still struggling with those “lung attacks,” as AstraZeneca’s Sharon Barr, Ph.D., called them, despite using standard-care inhaled therapy. In the headline results, a 300 mg dose of tozorakimab given once every four weeks curbed those moderate and severe exacerbations in the studies’ primary population of former smokers by 29% in the Oberon study and 34% in Titania. In the overall population of both current and former smokers, these reductions were 30% and 29%, respectively, versus placebo and inhaled standard of care. The benefits also extended to clinically meaningful exacerbation reductions in all prespecified patient subgroups and specifically turned up promising signals in patients across a range of blood eosinophil counts, with Barr telling Fierce that “it’s the details that make this even more exciting than the high-level results that we’ve already shared.” In fact, during AZ’s tozorakimab poster presentation at the ERS 2026 Congress this past weekend, attendees were so enamored by the data that event organizers had to encourage people to clear the room and look at the other presentations on offer, Barr said in an interview. “I think it really speaks to the fact that there is a lot of buzz around these data because the entire respiratory community has been so desperate for new therapies for these patients,” she explained. The respiratory disease continues to represent a “staggering unmet medical need,” Barr said, highlighting the COPD exacerbations that the Oberon and Titania studies homed in on, which she added carry a greater mortality risk than a heart attack. “When a patient has a severe exacerbation, only about half of them are still alive within three and a half years,” she pointed out. As for tozorakimab specifically, Barr christened the molecule “an AstraZeneca science success story,” harkening several years back to the point at which researchers began to explore IL-33 as a driver of respiratory disease, and COPD in particular. At the same time, “there was still so much that wasn’t understood,” she admitted, highlighting the insight that IL-33 signals through both ST2 and EGFR through the RAGE pathway, a discovery Barr attributed to AstraZeneca's own scientists. Understanding the need to tackle both pathways in COPD—and aware of competitor candidates in the hopper, including one that bound ST2—the company ultimately had to make some “courageous decisions,” Barr said. These included taking a prior COPD molecule offline and going back to the drawing board to reinvent its potential IL-33 label “to make sure that we had a molecule that could block signaling through both arms of the pathway, through both the reduced form and the oxidized form, knowing that we wouldn’t be first, but striving to be best.” “When we put [tozorakimab] into the clinic, we firmly believed that we had a differentiated molecule, and we saw the other molecules blocking just ST2 or partially blocking IL-33, unable to deliver two positive pivotal studies in COPD,” Barr explained. “We kept marching forward because we believed our molecule was differentiated, and now I think we have the clinical validation that supports that.” Ultimately, AstraZeneca finds itself on much better footing these days when it comes to potential biologic rivals to tozorakimab in COPD. Sanofi and Regeneron’s Dupixent, for instance, is approved to treat COPD exacerbations in patients with high eosinophil counts, but not low ones. Meanwhile, the future has become cloudier for other next-gen IL-33 candidates from Sanofi and Regeneron, as well as Roche, which have suffered trial flops in recent years. One other potential ingredient for AstraZeneca’s success in its duo of studies was that the company was “ambitious in the trial design, willing to look at an all-comers population,” Barr said, “and willing to enroll the most severe patients.” Prior studies for would-be biologics rivals in COPD “avoided enrolling” those patients, she pointed out. She also highlighted the Big Pharma’s painstaking design of exacerbations in its trial, which “gave us a very rigorous readout,” and pointed to “the extra effort and investment” the company put in to understand the effect of mucus plugs in patients. Barr described mucus production as a “key feature in disease diversity,” noting that mucus plugs—obstructing clumps of mucus that block patients’ airways—are associated with worse outcomes in COPD. In its data announcement, AstraZeneca noted that an integrated analysis of Oberon and Titania found tozorakimab “demonstrated a reduction in patients’ mucus plug score,” with the pharma claiming its biologic is the first to deliver such results in a broad COPD population. “So being able to reduce those mucus plugs, we expect, is an important part of driving benefit for patients who are living with COPD,” Barr said. Again touching on the breadth of the study populations, Barr added that tozorakimab “worked across all eosinophil levels in both current and former smokers across all levels of lung function,” which she suggested “really simplifies decision-making for clinicians, and it allows them to offer therapy to the broadest possible patient population.” In the highest patient eosinophil count group, tozorakimab helped chart a 43% reduction in exacerbation risk, which Barr stressed were “unprecedented data.” In the mid-level group, AZ’s drug delivered a 23% reduction and, in the lowest group, a 34% reduction in eosinophils, which Barr said suggests efficacy “in all patient subgroups.” As for AZ’s recent guidance upgrade on the medicine’s sales opportunity, the lift from a $3 billion to $5 billion range to $5 billion plus was informed by multiple factors, Barr said, including the fact that “in 2024, there were multiple competitors, and there aren’t anymore.” Additionally, “we know that this is a massive unmet medical need, and this is a really incredible set of data that we think will be very convincing to the clinical community,” Barr said. Looking ahead to a potential evolution of the COPD treatment landscape, Barr noted that most patients start treatment in the community with an option like a triple therapy, and for them, having an option like AstraZeneca’s inhaler Breztri will remain a “really important part” of that journey. But of the patients uncontrolled on triple therapy, which Barr described as “about half of them today,” just a “small fraction” are currently eligible for biologic therapy, which she emphasized AstraZeneca is working to change. Understanding that COPD is not a “one-size-fits-all” disease, AstraZeneca is also looking at its antibody drug Tezspire for patients with T2-driven disease, and the company continues to think about new mechanisms for tackling COPD through both systemic and inhaled drugs, Barr said.
UC Berkeley Law event targets Trump science policies as ‘censorship’
The University of California, Berkeley School of Law organized an Aug. 25 discussion focused on resisting censorship and protecting academic freedom in scientific research.
Swan Island businesses brace for I-5 closure
Freight, shipyard and service businesses have little room to dodge the traffic.
More than 1.6 million people die each year from secondhand smoke
The share of the population exposed to tobacco smoke is falling, but more than 2.7 billion people worldwide are still affected
Business Aviation & AAM Appointments: Royal Aeronautical Society, Cutter Aviation, And More
Lindsey Oliver of BBGA is honored as a Royal Aeronautical Society fellow, while Cutter Aviation and Skyfarer announce key leadership appointments.
Could High-Tech Toys Help Animals Act More Wild?
Zookeepers are trying a new fix for animal “boredom.”
One Off Hospitality is expanding Avec’s upcoming North Shore location
The restaurant group acquired more real estate, and plans to add a private event space to the restaurant.
Stevie Nicks’ fans praying for her after heartbreaking announcement. Here’s the latest
The singer has yet to comment on the tragic news.
Washington: Despite fueling AI’s wrong answers, data centers are uniting Dems and the GOP
Politicians from both sides of the aisle are raising strikingly similar concerns about water, energy and costs. The question is how long the unity will last.
DORAY Science and Technology Award Goes to KAIST, Gyeongsang National University Professors
DORAY Science and Technology Award Goes to KAIST, Gyeongsang National University Professors Five Young Scientists Receive 150 Million Won Fellowships Each for Three Years
Asian shares and US futures are mixed, while oil prices creep higher
Asian shares and U.S. futures are mixed after U.S. markets were closed for the Labor Day holiday.
Business of the Week: Tioga Downs
NICHOLS, N.Y. (WIVT/WBGH) – Tioga Downs Casino and Resort is the Greater Binghamton Chamber Business of the Week. Located in Nichols, it has a hotel, pools, casino, horse racing track and man…
Opinion: Bad optics and bad politics with fisheries decision
A North Carolina fisheries ruling enters its remedy stage as debate intensifies over inshore net fishing, agency performance and the General Assembly’s constitu...
Opinion: Bad optics and bad politics with fisheries decision
A North Carolina fisheries ruling enters its remedy stage as debate intensifies over inshore net fishing, agency performance and the General Assembly’s constitu...
Opinion: Bad optics and bad politics with fisheries decision
A North Carolina fisheries ruling enters its remedy stage as debate intensifies over inshore net fishing, agency performance and the General Assembly’s constitu...
Austin Living: Mad science and hot sauce
Homegrown business is bringing spice to people’s meals.
Autumn, finally: A season to calm our politics
As autumn arrives, columnist Tom Purcell urges Americans to step back from political stress and focus on friends, family and seasonal traditions.
Benton Neighbor Days parade draws crowds despite early Septe...
Benton Neighbor Days parade drew crowds as floats, bands, vehicles and horses rolled through early September heat.
Zach Gilford is glad he wasn’t cast as Reid on ‘Criminal Minds’ years before joining revival
‘Criminal Minds’ star Zach Gilford auditioned for Reid in the 2005 pilot, but he has no hard feelings about not even getting a callback: ‘It would’ve been more boring if it was me,’ he tells EW.
5 Android Phones More Powerful Than The Google Pixel 11
Google recently launched the Pixel 11 with its Tensor chipset and a price hike, but alternatives from OnePlus, Samsung, and Motorola are more powerful.
PAS chief to face Malaysian police over explosive US remarks
The US has rejected Abdul Hadi Awang’s claim that it offered help to change Malaysia’s political leadership during Obama’s visit in 2014.
Beyond grades: What parents expect from private schools
Changing times are reshaping parents’ expectations of private and independent schools. Parents look for much more than high grades and test scores.
You may ask yourself, how did I get here?
Bill Posley presents show military service at Solo Flights
Fuel prices at record Labor Day high in US thanks to Iran War, refinery issues
The average price of regular gas was $4.14 a gallon heading into the holiday, according to AAA motor club.
The chemistry helping to unravel the Bayeux Tapestry’s secrets
As the Bayeux Tapestry comes to the British Museum, scientists reveal how chemistry and imaging technology are unlocking its hidden history
Far-right win in state election tests Germany's political firewall
One small party could decide whether AfD governs.
Registration to open Sept. 14 for free BG Chamber of Commerce Women in Business Luncheon
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Woman found dead after work-related incident at Perham business
A 47-year-old woman was found dead early Friday morning following a work-related incident at Swan Machine in Perham, according to the Perham Police Department.
Which Music Streaming Service Has The Best Audio Quality?
Not all streaming apps handle high-resolution audio equally. Here is how platforms like Tidal, Apple Music, and Qobuz compare on bitrates and lossless specs.
5 Cheaper Android Phones To Try Instead Of The Google Pixel 11
Previous-generation flagship phones are still excellent and now they go for cheaper. That includes the Google Pixel 10 and Samsung Galaxy S25.
BGCSCK names new CEO
Boys & Girls Clubs of South Central Kansas has named Kyle Ellison as its new chief executive officer, effective Sept. 1. Ellison previously served as interim CEO and chief operating
The 92-Year-Old Mathematician and the Teenage Apprentice
Joan Birman thought her major discoveries were behind her. Then came an email from a young neighbor — a girl who knew little but wanted to learn.
How small can a transistor get?
How small can a transistor actually get? And is smaller even still the goal?
‘Evil Dead’ Star, 68, Shares Heartbreaking Health Update
In March, the actor shared the news that he had been diagnosed with a “treatable” but not “curable” form of cancer.
Dresses For Pink hosts health fair
Dresses for Pink and Lily Missionary Baptist Church will host a free health and wellness fair Sept. 19 in Letohatchee, offering screenings, speakers, nutritioni...
10 Desk Gadgets Under $100 That Deserve A Spot In Your Home Office
While big-ticket items get all the attention, there are also some relatively affordable desk gadgets that you can buy to upgrade your current setup.
Country music star’s fans praying after horrific wreck leaves him blinded in one eye
He was in the crash in early August.
Treg Taylor is back in Alaska’s race for governor after election officials reverse decision
The former Alaska attorney general had previously been removed from the ballot for failing to follow the state’s financial disclosure laws.
DeKriek completes trilogy with ‘My Mother at Last’
SIKESTON — For LaDona DeKriek, telling her life story has never been about presenting a perfectly polished journey.
Pop culture happenings: September
It was 50 years ago when Kermit and gang put on a show, 40 years ago when Oprah made daytime talk personal, and 25 years ago when 9/11 made it hard to find much...
For feminists, the deaths of Parton and Steinem days apart deliver a double dose of grief
The deaths of Gloria Steinem and Dolly Parton just days apart have delivered a double dose of grief for feminists.
For feminists, the deaths of Parton and Steinem days apart deliver a double dose of grief
The deaths of Gloria Steinem and Dolly Parton just days apart have delivered a double dose of grief for feminists.
EAST TEXAS POLITICS: Smith County GOP chair previews RNC midterm convention, reacts to Trump’s data center remarks
Smith County GOP Chairman David Stein joins Blake Holland ahead of next week’s convention in Dallas
‘Big Brother’ star Lala blasts Drew and Haley on her way to the jury house
Lala blasts Drew and Haley on her way to ‘Big Brother’ jury house, and reveals she thought she had the votes to stay.
Trump says he will spend some, not all, super PAC money on midterms
Republicans have fretted over his war chest sitting on the sidelines. The president says he plans to hold onto some of the money for 2028.
Guthrie, Oz promote rural health funding in Glasgow visit
GLASGOW — U.S. Rep. Brett Guthrie, R-Ky., and Centers for Medicare and Medicaid Services Administrator Dr. Mehmet Oz visited T.J. Health Pavilion in Glasgow on Friday morning to meet with […]
The Deloreans bring ’80s music to Boykin Center
The Deloreans, an ’80s tribute band, open Wilson Arts’ Boykin Series 29 on Sept. 11 at the Edna Boykin Cultural Center.
Terri Irwin recalls final days, ‘long and sweet goodbye’ with husband Steve Irwin 20 years after his death
Terri Irwin recalled her final days with late husband Steve Irwin in an emotional tribute, 20 years after his death on Sept. 4, 2006.
Can AI answer your health questions? Before you trust AI with your...
Can AI answer your health questions? Before you trust AI with your health, make sure you know the pros and cons. #Sashaonyourside #consumernews #ConsumerAlert #AI #HealthTips nbc6news
AMD Introduces Threadripper Halo Station at IFA 2026
The opening keynote at IFA 2026 was held by AMD and our team on the ground was there to see it. During the event, AMD announced the Threadripper Halo Station, a liquid-cooled workstation built around the 96-core Threadripper PRO 9995WX CPU codenamed "Shimada Peak" and up to four AMD Instinct...
Some area business owners seeing more break-ins since World Cup left Seattle
“We love Seattle. We’ve seen what it can be. There’s no reason why it cannot grow into what it was during the World Cup, an event that was only a month ago. We’re not giving up," one business owner said.
UGREEN's new local AI NAS is the most well-thought-out smart home product I've ever used
Keep it local. Keep it safe. Keep it subscription-free.
Democrats eye expanded Medicare coverage if they take U.S. House
Reversing Medicaid cuts and restoring ACA subsidies top the list, but Democrats are also talking about lowering the age of eligibility for Medicare benefits.
Democrats eye expanded Medicare coverage if they take U.S. House
Reversing Medicaid cuts and restoring ACA subsidies top the list, but Democrats are also talking about lowering the age of eligibility for Medicare benefits.
Sony’s State of Play Was Overshadowed By Angry PS5 Fan Demands
The PS5 State of Play showcase was full of angry fans asking for new policies as well as the development of Destiny 3
Longtime flea market announces closure after 47 years in business
Luke's Flea Market owner Judy Rice says she is retiring.
These 12 Central Florida restaurants shut down last week over health problems
Last week, a dozen more Central Florida eateries were forced to shut down (at least temporarily) after a visit from a health inspector, according to state records.
Soft opening announced for new Henderson sports, entertainment complex
Henderson Sport and Social offers indoor soccer, bowling, and an arcade without requiring families to walk through a smoky casino.
Soft opening announced for new Henderson sports, entertainment complex
Henderson Sport and Social offers indoor soccer, bowling, and an arcade without requiring families to walk through a smoky casino.
Livestock, rides, games and music mark opening night at 2026 Great Allentown Fair (PHOTOS)
The Great Allentown Fair opened with a performance by The Four Tops and the Allentown Symphony Orchestra.
South African scientists could face year in prison unless ...
Researchers warn that registration offers little benefit and that the associated costs will disadvantage early-career researchers
‘Fresh Prince’ alum Tatyana Ali wasn’t allowed to tell host Alfonso Ribeiro she joined ‘DWTS’
Tatyana Ali reveals why she wasn’t allowed to tell her ‘Fresh Prince of Bel-Air’ brother Alfonso Ribeiro that she’d been cast on season 35 of ‘Dancing With the Stars,’ which he’s cohosted since season 31.
Moment of Science: New study finds humans and animals share certain sound preferences
Answering the call of the wild! Here's how our sound preferences stack up against other animals, from birdsong to baboon barks. 🐦🔊
Broadcom forecasts quarterly revenue below estimates
Broadcom forecast quarterly revenue below Wall Street estimates on Wednesday, signaling intense competition could hamper gains from its custom processors.
Applications open for three-county downtown business pitch competition
Middle Michigan Development Corporation is hosting businesses and entrepreneurs from across the region for the 2026 Middle Michigan Downtown Pitch.
Six Takeaways From the Massachusetts Primaries
Senator Ed Markey, 80, trounced a younger challenger who had made an argument for generational change. Two other longtime Democratic lawmakers hung on, too.
Kalshi, Polymarket, growing as political platforms
How election pollsters think about about the rise of prediction markets.
CDP supporting local businesses
The CDP works to connect businesses with resources, organize community events, and strengthen the relationship between local businesses and the community.
How SBGA Helps Small Businesses Build Operations That Keep Up With Growth
. According to the U.S. Small Business Administration, small businesses account for the vast majority of American companies and employ nearly half the private-sector workforce.
US oil firm to take over some Venezuelan oilfields previously run by Chinese, Russian companies, officials say
U.S. oil company North American Blue Energy Partners will take over some oilfields previously controlled by five Chinese companies and a Russian firm, two U.S. officials told Reuters on Monday.
Business of the Week: Doron Precision Systems
KIRKWOOD, N.Y. (WIVT/WBGH) – Doron Precision Systems is the Greater Binghamton Chamber Business of the Week. Founded in 1973, Doron is a local business consisting of about 45 people that specializes i...
Boston 25 News
A family business in Somerville is trying to bring awareness to the huge need for people in Nepal after devastating floods there last week.
The U.S. Supreme Court removed limits on political parties coordinating with candidates. What does that mean for Philly’s elections?
Local elections lawyers said the Supreme Court's decision could potentially boost the spending power of Philly's political parties.
Celebrating Gregg Allman at the Wheeler
Wednesday event combines live music, film screening, panel
4 Compact Tablets Perfect For Reading And Entertainment
Compact tablets strike the perfect balance between immersive entertainment and portability, so we've picked some great options from Apple, Lenovo, and Samsung.
Walthourville community honors beloved business owner
A Walthourville community honored the legacy of a beloved local business owner Saturday.
I’m a mental health expert. Here’s how I would search for an online therapist.
Online treatment can be just as effective as traditional in-person visits, but certain strategies can help ensure the best outcome.
March on Washington anniversary draws calls to defend the vote
Hundreds gathered in Washington, D.C., on the 63rd anniversary of the historic March on Washington to defend voting rights, civil rights and economic justice am...
Pomona to Host Symposium Examining African Politics and Global Relationships | Pomona College in Claremont, California
Through an early Center for Global Engagement (CGE) initiative, Professor Pierre Englebert’s “Africa After the End of History” symposium and course will examine how the rest of the world now interacts with African nations.
Alaska campaign watchdog says Treg Taylor should not be allowed to run for governor
A state commission says Taylor, a former attorney general, failed to file a financial disclosure as required by law.
Data center controversies have transformed midterms. Here's where different groups stand
Snowballing opposition to data centers in communities across the U.S. has transformed the midterm election landscape, thrown a wrench into the plans of the world’s richest companies and brought President Donald Trump to its defense.
Supporting State and Local Health Policy Leaders Through High-Stakes Change
News article: Welcoming 2026-27 Milbank State Leadership Program Cohorts Improving health outcomes through gubernatorial transitions and amid significant federal
A.Y. Strauss adds Penny Paul as Director of Marketing & Business Development
A.Y. Strauss LLC announced Aug. 26 that Penny Paul has joined the firm as Director of Marketing & Business Development.
Ottawa taps 64 leading scientists and scholars to bolster Canadian research
The first group of Eddie Goldenberg Research Chairs of Canada includes researchers from 13 countries, with most leaving institutions in the U.S.
Iconic singer known for hits and risqué TV spot dead at 94: ‘There was only one’
She rose to fame in the 1950s.
‘There’s a whole process’: Bangor business owner highlights needle disposal challenges after patio incident
James Gallagher owns Bangin’ Whoopie in Bangor. He said he was first alerted to the person injecting drugs by a five-year-old and her grandmother.
Using FDA addiction science, researcher asks: Do salty, high-fat foods act like drugs?
Click for more on new grant from the National Institutes of Health
DAZN acquires EverPass, rebrands it DAZN for Business
DAZN has acquired EverPass -- and the commercial distribution rights to NFL Sunday Ticket along with it -- as the London-based company continues to infiltrate the U.S. sports marketplace. It will rebrand EverPass as "DAZN for Business" with the NFL's 32 Equity as a minority shareholder.
Employers face ‘existential reckoning’ as health costs surge
Employers are expecting a median 9.2% increase in medical spending next year, according to a new survey. But they’ve underestimated actual cost growth for the past three years, so even that figure may be too optimistic.
Cinq à Sept Built a $200 Million Business. Now It Wants Your Attention.
The 10-year-old label has built a thriving womenswear business that outsells buzzier competitors. Its next goal is to grab some of that buzz for itself.