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WHO updated recommendations on HIV clinical management: recommendations for a public health approach
This document provides an overview of the updated World Health Organization recommendations for HIV clinical management, which focus on optimizing antiretroviral therapy, preventing vertical transmission, and enhancing tuberculosis prevention among individuals with HIV. These updates are intended to support global initiatives aimed at ending AIDS as a public health threat by 2030. Key changes include the introduction of new antiretroviral drugs and regimens, revised postnatal prophylaxis and breastfeeding guidelines for managing infants at risk of vertical transmission, and the endorsement of shorter tuberculosis preventive treatments to improve efficacy and adherence. The recommendations are designed to simplify and advance HIV care, promote equity, and contribute to improved health outcomes and quality of life for individuals living with HIV. The updated guidance will be incorporated into the forthcoming revision of the antiretroviral therapy chapter within the Consolidated Guidelines on HIV Prevention, Testing, Treatment, Service Delivery, and Monitoring: Recommendations for a Public Health Approach.
Shake Shack rolls out health-oriented menu
The ‘Good Fit’ lineup of curated items focuses on protein while also offering low-carb, vegetarian, and gluten-free options
Sphere Entertainment: High Short Interest And A Promising Outlook (NYSE:SPHR)
Sphere Entertainment Co. (SPHR) is rated Hold, balancing strong immersive entertainment growth against high short interest and valuation concerns.
The disunity of science is a feature, not a bug
Mathematical models wield miraculous power, but mistaking them for reality has trapped science in a destructive quest for a “Theory of Everything.” Physicist and philosopher Ragner Fjelland argues that this leads to bloated, Frankenstein theories kept alive by clumsy, ad-hoc amendments, which reduce rather than boost science’s power. Fjelland calls for a radical shift in our attitude: we must reorientate towards creating entirely new theories, celebrating rather than lamenting disunity and diversity in science. Science, from the scientific revolution in the seventeenth century to the present day, has more or less developed in a “reductionist” way. The fundamental assumption is that all sciences may be ordered in a hierarchy that can be represented as an upside-down pyramid. At the top we find the human sciences, and at the bottom physics. Strong (or “ontological”) reductionism maintains that all theories at one level can be completely reduced to the lower level, all the way down to theories of atoms and elementary particles, or whatever is “at the bottom.” In the end, all diversity in the world can be unified in one fundamental theory. Hence it is called a final theory, or a Theory of Everything.One of the central figures in developing the idea of a Theory of Everything is the Dutch theoretical physicist Gerard 't Hooft, who received a Nobel Prize in physics in 1999 for his work. He emphasizes the non-empirical status of the theory:There exists no closely resembling alternative theory. This means that any slight change brought about in the rules would make the theory unlikely or inelegant. The theory will be a "package deal": take it, or leave it. This should hold both for the local laws and for the boundary conditions.This endeavor is not new. On the contrary, it goes all the way back to the birth of Western philosophy 2,500 years ago. The Babylonians made regular astronomical observations during a period of 600 years, from 747 BCE until 150 ACE. They developed mathematical techniques to predict astronomical phenomena, but they made no attempts at explaining them. However, the Greeks developed models, both material and theoretical, to explain the observed phenomena.The best example is Plato’s late dialogue Timaeus. Here he introduces a divine craftsman, the Demiurge, who has constructed the universe according to an original plan. Plato seems to have thought that the original plan is what is actually real, while the material world is merely an imperfect realization of it. He therefore does not, in the Timaeus, reconstruct the material universe, but the original plan, which can then be used to explain the material universe.Plato’s aim in producing a theoretical model is to reconstruct the original plan. That is what he carries out in Timaeus—and some modern physicists have embarked on the same project. For example, Einstein’s basic attitude is reflected in the title of Abraham Pais’ biography: “Subtle is the Lord...,” echoing Einstein’s comment, “Subtle is the Lord, but malicious He is not.” In an interview Einstein compared our situation to a child who enters a huge library. The child knows that someone has written the books, but he does not know the languages in which they are written. He suspects that there is a mysterious order, but he does not know what it is.___“We have all been working in what Husserl called the Galilean style; that is, we have all been making abstract mathematical models of the universe to which at least the physicists give a higher degree of reality than they accord the ordinary world of sensation.”Steven Weinberg, Nobel Prize in Physics (1979)___This Platonist view is contrary to a widespread impression of science, symbolized by the picture of the “father” of modern science, Galileo Galilei, with his telescope. According to this impression, Galileo liberated himself from the dominating metaphysics of his day—basically Aristotelian philosophy—and constructed a telescope that he directed towards the sky, showing that Jupiter has four moons. He also performed experiments with bronze balls rolling down inclined planes and found the law of freely falling bodies.However, in other cases Galileo emphasized the unreliability of our senses. It is easy to see why. He defended Copernicus’ heliocentric hypothesis. According to this hypothesis, we are not at rest at the center of the universe, but moving at a tremendous speed through space. Why don’t we observe this motion? Galileo praises Copernicus because “with reason as his guide he resolutely continued to affirm what sensible experience seemed to contradict.” In other places he directly refers to Plato. SUGGESTED VIEWING The quest for a final theory With Michio Kaku Galileo’s Platonism goes back to his early writings. In The Assayer, published as early as 1623, Galileo compared the universe to a grand book that is written in the language of mathematics, and “its characters are triangles, circles, and other geometric figures without which it is humanly impossible to understand a single word of it.” Therefore, things that cannot be described by mathematics—for example, colors, smells and odors—are not real. They are merely subjective.This division into subjective and objective, advocated by Galileo and his younger contemporary René Descartes, is normally associated with a mechanistic world view, which is regarded as the opposite of Platonism. When we reduce something to, for example, molecules and atoms, we move “downwards.” In contrast, the Platonist moves “upwards,” to abstract entities. However, it only shows that when we address fundamental questions, we should be careful in applying everyday spatial metaphors like “up” and “down.”___Nature is complex, and we cannot in general construct mathematical models that adequately describe the world.___The endeavor of finding a Theory of Everything has been heavily criticized. In 2006, the theoretical physicist Lee Smolin published “The Crisis in Fundamental Physics.” He argued that one of the most fundamental principles of science is that we should only regard theories as scientific if we have the possibility to show that they are false by experiments. Although he did not refer to Karl Popper, other critics have referred to Popper and argued that a theory is not scientific if it cannot be falsified (see for example Ellis & Silk 2014).These were not the first physicists to be anti-reductionists. In 1972, the journal Science published an article by the physicist Philip Anderson with the title “More Is Different.” This is the kind of article a scientist would normally write only after he has won a Nobel Prize. However, Anderson won the Nobel Prize for physics five years later, in 1977. The article is amazing, not primarily because it argues in favor of anti-reductionism in general, but because it argues for anti-reductionism within physics itself. Anderson’s conclusion was:At each stage entirely new laws, concepts, and generalizations are necessary, requiring inspiration and creativity to just as great a degree as in the previous one. Psychology is not applied biology, nor is biology applied chemistry.We may say that Plato started the “unity of science movement,” based on Euclidean geometry as the model of all knowledge. A distinguishing mark of geometry is that all possible constructions can be reduced to a few fundamental principles. We have to acknowledge that this approach has limitations. In general, we can easily model technological systems. In addition, we may construct simplified and idealized models that capture important aspects of systems, from various perspectives and for various purposes. But nature is complex, and we cannot in general construct mathematical models that adequately describe the world. In a complex system, each level has its distinct, emergent, properties that are characteristic of this level. Therefore, a complex system should be investigated at different levels and from different perspectives. Instead of exclusively pursuing a scientific ideal based on the unity of science, we should acknowledge the diversity—or even the disunity—of science.
I Tried Honor's Win Gaming Phone: It's Built Like a Tank and Has a Behemoth Battery
The Honor Win is the first flagship gaming phone with a cooling fan and a 10,000-mAh battery that's rated for both dust and water resistance.
Roman Henry named Sports Illustrated National Player of the Week
Henry has scored 155 points in his first 6 games
Holly Gleason Receives National Arts & Entertainment Journalism Awards
NY Times No. 1 best-selling author Holly Gleason recently celebrated six awards from [...]
Judge presses Trump administration on its plans for Kilmar Abrego Garcia
An apparently frustrated federal judge pressed the Trump administration Monday to share what it was going to do next in the fast-moving saga over Kilmar Abrego Garcia days after she found he was being unlawfully held in immigration custody.
Maridea Wealth Launches Tax & Business Services Unit With Strategic Acquisition of Hyperion Accounting Group
BROOKLYN, N.Y., December 22, 2025--Maridea Wealth ("Maridea") today announced the launch of its dedicated Tax & Business Services unit, marking a major expansion of the firm’s mission to provide clients with a comprehensive, integrated financial-services platform. As part of this initiative, Maridea is acquiring Hyperion Accounting Group, led by David Papotta, who will join as Director of Tax & Business Services.
Governors’ Health Priorities in 2025
Through emergency response, behavioral health investments, maternal health protections, nutrition innovations, rural health transformation, and workforce development, Governors have demonstrated that effective governance requires evidence-based policymaking, cross-agency coordination, and sustained political will. Governors confronted complex challenges with innovative solutions grounded in evidence and adapted to local contexts. As highlighted at the 2025 Health and Human Services Policy Advisors Institute, states […]
Launch Family Entertainment closes out 2025 with record growth, six new openings, and accelerated multi-unit development
WARWICK, R.I. – Launch Family Entertainment (Launch), a leading indoor family entertainment franchise, is ending 2025 with major development milestones, including six new park openings, 13 secured …
San Mateo seeks to solidify local business
As San Mateo approves a three-year economic development plan, the City Council reiterated the need for diversifying its small business base — ensuring key establishments such as grocery stores and
Christmas Candlelight Tour in Kirkwood celebrates magical holiday season [photos]
The Christmas season was celebrated in a magical way at the Gnome Countryside's Christmas Candlelight Tour in Kirkwood on Friday through Sunday evenings. Tours featured a bonfire, storytelling, songs, a
Dan Campbell was FRUSTRATED about how game ended 😡
Dan Campbell was FRUSTRATED about how game ended 😡
Fact-checking Trump’s plaques for past presidents at the White House 'Walk of Fame'
In a break from tradition, President Donald Trump decorated a White House walkway with bronze plaques for each U.S. president. In an even sharper break with tradition, the plaques were written in a style echoing Trump’s Truth Social posts, with misleading or false descriptions of recent Democratic presidents.
In affordability speech, President Trump mentions his neuroses, his favorite armchair, and the First Lady’s underwear
Redwire Corporation (RDW) Poised for Growth on Defense Business Model Transition: Cannaccord Genuity
Redwire Corporation (NYSE:RDW) is one of the best aerospace and defense stocks to buy according to Wall Street analysts. On December 9, Canaccord Genuity analyst Austin Moeller reiterated a Buy rating, impressed by Redwire Corporation (NYSE:RDW)’s strategic positioning and growth potential. According to the analyst, the company is positioned for long-term growth as it transitions […]
Strengthening U.S.-Nigerian Health Cooperation under the America First Global Health Strategy - U.S. Embassy and Consulate in Nigeria
Strengthening U.S.-Nigerian Health Cooperation under the America First Global Health Strategy The United States signed a five-year, $5.1 billion bilateral health cooperation Memorandum of Understanding (MOU) with the Federal Republic of Nigeria December 19 to advance the America First Global Health Strategy, supporting resilient, self-reliant, and durable health systems while promoting accountability and shared responsibility. Under the five-year MOU, the United States intends to commit nearly $2.1 billion in health assistance, with nearly $3.0 billion in new domestic health expenditures by the Government of Nigeria over the same five-year period. This represents the largest co-investment any country has made to date under the America First Global Health Strategy and underscore Nigeria’s commitment to greater national ownership of its health system. Under the MOU, the United States will continue to support surveillance and outbreak response, laboratory systems, health commodities; frontline healthcare workers, and data systems. Nigeria faces significant health challenges, including one of the highest maternal and child mortality rates globally and approximately30 percent of the global malaria burden. U.S. assistance under the MOU will expand access to affordable, preventive and curative services for HIV/AIDS, tuberculosis (TB), malaria, polio, and maternal and child health, strengthening health outcomes across Nigeria. The MOU places a strong emphasis on Christian faith-based healthcare providers, recognizing their indispensable role in delivering care to communities in need. Nigeria’s more than 900 faith-based clinics and hospitals serve more than 30 percent of the country’s 230 million people, often in areas where healthcare facilities are limited or absent. The MOU provides approximately $200 million in dedicated support to strengthen and support these Christian facilities, enhance workforce capacity, and expand access to integrated HIV, TB, malaria, and maternal child health services. Investments in Christian faith-based health institutions are uniquely positioned to complement public-sector facilities and reinforce Nigeria’s overall health infrastructure. The MOU was negotiated in connection with reforms undertaken by the Government of Nigeria to prioritize the protection of Christian populations from extremist violence. As with all U.S. foreign assistance, the President and Secretary of State retain the right to pause or terminate programs that do not align with U.S. national interests, and the United States expects Nigeria to continue making measurable progress in combating religiously motivated violence against Christian communities. This five-year MOU is the latest of several health cooperation MOUs signed in Africa this month. The United States will continue to sign multi-year Bilateral Agreements on Global Health Cooperation with countries receiving U.S. health assistance to advance the America First Global Health Strategy.
Pennsylvania's role in ACA subsidies debate crystalized health care as a dominating political force in 2026 midterms
WASHINGTON — Lynn Weidner, a 42-year-old home care worker from Allentown, had already spent much of this year frustrated with her congressman...
Pennsylvania's role in ACA subsidies debate crystalized health care as a dominating political force in 2026 midterms
WASHINGTON — Lynn Weidner, a 42-year-old home care worker from Allentown, had already spent much of this year frustrated with her congressman...
10 greats set for enshrinement to Beaver County Sports Hall of Fame
Penn State interim head coach Terry Smith, an Aliquippa native, and professional wrestling champion and New Brighton native “The Franchise” Shane Douglas are two of a group of 10 athletic greats who will be celebrated with enshrinement into the Beaver County Sports Hall of Fame on June 13 at The Club at Shadow Lakes in Aliquippa.
Small businesses finally get their moment after Small Business Saturday delayed twice
Small Business Saturday was celebrated in Peoria, IL after two weather postponements, with local small businesses reporting steady foot traffic and strong customer support.
The 15-inch Surface Laptop 7 with 32GB RAM and a 1TB SSD is 30% discounted — a rare deal as memory prices keep climbing
One of the best laptops we've ever rated for its sublime performance, battery life, and perfect form factor is 30% off for Amazon's Super Saturday sale.
Cal Raleigh adds Sports Illustrated's 'Breakout Star of the Year' to year of accolades
"Big Dumper" has been named the "Breakout Star of the Year" by Sports Illustrated.
East Lyme business owner sentenced to probation for tax fraud
An East Lyme woman who operated a cleaning business was sentenced to three years of probation for tax fraud after underreporting her income by hundreds of thousands of dollars.
PR Veteran Jeff Tobler Joins Universal TV Entertainment as Senior VP of Awards and Integrated Communications (EXCLUSIVE)
Warner Bros., Array and Expedia PR vet Jeff Tobler has joined Universal TV Entertainment as senior VP of awards and integrated communications.
The Ten Most Significant Science Stories of 2025, From Medical Breakthroughs to an Interstellar Visitor
All year long, these moments captivated the public, demonstrated dangerous trends, and pushed research and innovation forward
Integrated Business Program Students Turn Classroom Experience into Community Impact
Students in the College of Business Integrated Business Program worked together to support charities. (ULV Photo/Sasha Chavez) Students Translate Entrepreneurial Skills into Charitable Contributions Students in the College of Business Integrated Business Program presented nearly $15,000 in donations to local and national charities during a ceremony at the Sara and Michael Abraham Campus Center. The […]
UN agencies welcome news that famine has been pushed back in the Gaza Strip, but warn fragile gains could be reversed without increased and sustained support
The latest Integrated Food Security Phase Classification (IPC) analysis for Gaza confirms that no areas of the Strip are currently classified in famine following the October ceasefire and improved humanitarian and commercial access.
Trump debuted a new affordability script. It’s unclear to advisers whether he’ll stick to it
The White House is heading into a critical midterm year beset by economic challenges, as it tries to manage stubbornly high prices, a frustrated electorate and a commander-in-chief who struggles to show sympathy toward voters’ pain.
AEW and AEW Stars Win 10 Best of 2025 Awards From Sports Illustrated, Including Wrestlers of the Year and Promotion of the Year
This week, All Elite Wrestling and its Stars took home 10 awards from Sports Illustrated's 2025 Pro Wrestling Awards, including both the Female and Male Wrestler of the Year, as well as Promotion of the Year and many more.
Mental health ratings hit new low, 5 years after pandemic turning point
A new Gallup survey showed just 29% of people rated their mental health or emotional well-being as "excellent," a new low in Gallup tracking.
Google’s Gemini app can check videos to see if they were made with Google AI
Incremental deepfake detection.
Large Minnesota study underscores disproportionate rates of health problems among recently incarcerated and unhoused people
In a study of more than 4.3 million people in Minnesota, researchers found widespread disparities in health conditions between the general population and people who ...
Marshall Scholar examines the intersection of books, literature and politics
Jack Wallace, UVA’s 18th recipient of the scholarship, says critical thinking and literacy are antidotes for mistrust generated by technology.
Monumental Sports & Entertainment Announces Minority Investor Updates to Accelerate Growth and Innovation
/PRNewswire/ -- Monumental Sports & Entertainment ("MSE"), one of the nation's leading integrated sports, media, and entertainment companies, today announced...
‘14 strong.’ Gritty Kentucky volleyball faces program’s second-ever Final Four
No. 1 seed Kentucky volleyball is two wins away from becoming the most-decorated team in program history.
Insmed Provides Clinical and Business Update
/PRNewswire/ -- Insmed Incorporated (Nasdaq:INSM), a people-first global biopharmaceutical company striving to deliver first- and best-in-class therapies to...
Insmed Provides Clinical and Business Update
Insmed Incorporated (Nasdaq:INSM), a people-first global biopharmaceutical company striving to deliver first- and best-in-class therapies to transform the lives of patients facing serious diseases, announced today that the Phase 2b BiRCh study of brensocatib in patients with chronic rhinosinusitis without nasal polyps (CRSsNP) did not meet its primary or secondary efficacy endpoints in either the 10 mg or 40 mg treatment arms. Brensocatib was well tolerated, with no new safety signals identified
A new era for sports communication at UNC Hussman | UNC Hussman School of Journalism and Media
As director of UNC Hussman’s Sports Communication Focus Program, Distinguished Associate Professor of Sports Communication Livis Freeman is building on the work of the school’s legendary Distinguished Professor for Sports Communication John Sweeney. Sweeney, who retired last year, developed one of the most respected sports communication programs in the country. Freeman, now in his 12th year at the school, is launching an ambitious expansion of the program that is transforming how UNC prepares students for careers in sports media. The most visible change came this fall with a reimagining of “MEJO 377: Sports Communication.” Previously offered as two sections with 30 students each, the course expanded to 96 students and welcomed former UNC basketball star and NBA veteran Tyler Hansbrough as the co-instructor with Freeman, bringing real world professional experience directly into the classroom every week. The course has been a huge success. Students have participated in recording a podcast with Hansbrough and learned from an impressive lineup of guest speakers. Steve Kirschner, UNC’s senior associate director of athletics for communications, was the first in the course’s guest speaker series, followed by UNC Hussman alumni including Kaitlyn Schmidt ’23 from Bleacher Report, Deaton Bell ’90 from Turner Sports and Becca Royer ’19 from the Philadelphia 76ers. Travis Tygart, CEO of the U.S. Anti-Doping Agency, also shared his insights with the class. The highlight of the semester came when Roy Williams, who coached Hansbrough and the Tar Heels to a national championship in 2009, visited the classroom. Former UNC men’s basketball players Luke Maye and Marcus Ginyard showed up to support their former coach and Hansbrough, creating an unforgettable experience as Williams entertained students with stories and insights that captivated the room. Student demand has been overwhelming. The course reached capacity within two days of registration opening, with more than 40 students on the waitlist. “Students want to learn from people who have actually lived these experiences,” Freeman said. “Tyler shares insights into media relations, broadcast production and athlete communications that you simply can’t get from a textbook.” The model proved so successful that the school secured funding to continue it for the next five years, with a different former professional athlete co-teaching each fall. The school’s curriculum committee approved a proposal to expand the course to 150 to 200 students starting in fall 2026. This change will make it an introductory course accessible to students from across the University, transforming it into a showcase course for the entire campus. The course redesign represents just one piece of a broader sports communication program overhaul. This fall, the curriculum committee approved “MEJO 390: Sports Play by Play,” the first course of its kind at UNC. Limited to 10 advanced students, the course will be taught by Matt Krause, the current voice of UNC women’s basketball and an ACC Network broadcaster. Students will call actual games across multiple sports including women’s softball, soccer, volleyball, field hockey and lacrosse, as well as men’s soccer and lacrosse. They will also shadow broadcasts of men’s and women’s basketball games. “The sports broadcasting industry is exploding with streaming platforms and conference networks creating unprecedented demand,” Freeman said. The course emerged directly from student advocacy, led by Anna Laible ’26 and others who pushed for hands-on broadcasting experience. Professional equipment has been acquired, partnerships with UNC Athletics are in place and a soft launch began this semester with three experienced students calling games to test the system. The program’s growth extends into other specialized areas as well. Last spring, Stembler Professor Charlie Tuggle launched a new sports event management and hospitality course in partnership with On Location, a company that manages major sporting event experiences. The course provided students with opportunities to travel to the Super Bowl and NFL Draft, and Tuggle plans to take a group to the 2026 Milan Olympics this spring. Looking ahead to spring 2026, Associate Professor Ryan Thornburg will debut a sports data visualization course, adding another dimension to the program’s skill-building offerings. The curriculum expansion reflects the increasingly diverse career paths available in sports media, from traditional journalism and broadcasting to digital analytics and strategic communication. The program is also diving into one of college athletics’ most transformative developments: Name, Image and Likeness rights. Freeman’s “MEJO 466: Sports Marketing” class collaborated last spring with Associate Professor Gary Kayye’s “MEJO 371: Advertising Creative” class on a project with UNC’s Carolina NIL group to help rebrand their organization. That same semester, Kayye’s class envisioned Chapel Thrill, UNC football’s new pregame concert and entertainment experience. And Shaun Anderson, the school’s Knight Chair in Sports, Race and Media, continues to explore the broader implications of NIL through his research and teaching. These NIL-focused initiatives give students direct exposure to the business side of college athletics at a moment when the landscape is rapidly evolving. “Our students aren’t just learning about these changes,” Freeman said. “They’re actively helping shape how schools and athletes navigate them.” The transformation of UNC Hussman’s sports communication program reflects a broader philosophy about how to prepare students for careers in a rapidly changing industry. By bringing in professional practitioners like Hansbrough and Krause, partnering with industry leaders like On Location and ACC Network, and engaging with current issues like NIL, the program ensures students graduate with both theoretical knowledge and practical experience. For alumni who remember the foundations John Sweeney built, the expansion represents an evolution rather than a departure. The program still emphasizes strong reporting, strategic communication, ethical communication and critical thinking. But now it also offers students the chance to call live games, work on real NIL campaigns and learn directly from former professional athletes. “We’re not just teaching students about sports media,” Freeman said. “We’re giving them the tools, experiences and connections to actually build careers in it.” With new courses launching, professional partnerships deepening and enrollment expanding, UNC Hussman’s sports communication program is positioning itself as a national leader in preparing the next generation of sports media professionals. For current students, the message is clear: if you’re interested in sports communication, there’s never been a better time to be at UNC Hussman. And for the hundreds of students trying to get off waitlists and into these new courses, the school is working to create more opportunities. The program John Sweeney built is growing in ways that honor his legacy while meeting the demands of a new era in sports media.
'False hope': Why families who celebrated California's new mental health court feel let down by it
Ronda Deplazes thought Gov. Newsom's CARE Court could save her son as he struggled with mental illness. Almost three years later, she and other families say little has changed for them.
New Public Science Center Opens at Kitt Peak National Observatory - Visitors celebrated the opening of the Windows on the Universe Center for Astronomy Outreach, the first science center located inside a telescope
Windows on the Universe Center for Astronomy Outreach is a new science education and astronomy outreach center that has just opened at U.S. National Science Foundation Kitt Peak National Observatory, a Program of NSF NOIRLab.
9-1-1: Nashville brings jobs, signals growth for Tennessee’s entertainment industry
The production of “9-1-1: Nashville” has already created more than 600 jobs and generated an estimated $50 million in economic impact statewide, according to the Tennessee Entertainment…
The Most Underrated Movie Santa Claus Is...
Who is the best movie Santa Claus? Lots of people will say Tim Allen, Ed Asner or even Jack Skellington. But the most underrated movie Santa of all time? Definitely Kurt Russell from 'The Christmas Chronicles' on Netflix.
Larian is using generative AI, confirms CEO, but Divinity won't contain anything AI-generated
Larian is using generative AI as part of its game development process, but the studio's new Divinity game won't include anything AI-generated.
The war on saturated fat, never based on good science, can now end
As people cut more saturated fat, the nation grew heavier and sicker — not healthier.
Susie Wiles Talks About The First Year of Trump’s Second Term (Part 1 of 2)
In the first half of ‘Vanity Fair’’s interview with Susie Wiles, the chief of staff discusses Elon Musk’s DOGE disaster, the FBI’s “incredible job” investigating January 6, and how Trump once berated her.
Slam-dunk holiday gifts for women’s sports fans and superfans
You won't drop the ball this holiday season with our gift guide as your playbook. USA TODAY Sports curated a list that has something for everyone.
Preorder the Upcoming Book, Pokécology: An Illustrated Guide to Pokémon Ecology
Preorder the upcoming book, Pokécology: An Illustrated Guide to Pokémon Ecology, and get ready to learn about Pokémon in a whole new way.
World leaders adopt a historic global declaration on noncommunicable diseases and mental health
Leaders from across the world at the Eightieth United Nations General Assembly (UNGA) have adopted the political declaration to combat noncommunicable diseases (NCDs) and mental health challenges through a fully integrated approach. This is the outcome of the intergovernmental negotiations in advance of and considered by the fourth high-level meeting of the UNGA on the prevention and control of NCDs and the promotion of mental health and well-being, held on 25 September 2025.
Southwestern Middle School Holds Inaugural Science Fair
Students at Southwestern Middle School recently had the chance to show off their creative sides in a science fair for students in the Living Environment class. Students collaborated with each other to devise, research, and present the findings for various studies following organisms and living creatures. Students’ interest in their particular projects gave them enough […]
On Politics: Republicans are giving Kathy Hochul a re-election gift
It was already going to be hard for Elise Stefanik, the Republican congresswoman, to beat Gov. Kathy Hochul next year.Now she’ll have to contend with Bruce Blakeman, who recently announced his plans to run for governor and will, at the minimum, make life more difficult for her in the Republican primary. Stefanik has come out swinging against the Nassau County executive, attacking him as a perennial candidate who is too liberal for Republican primary voters.Stefanik should win. A large chunk of the GOP primary vote is concentrated north of the New York City suburbs, where she is strongest. She has the support of the state party chair, Ed Cox, and a wide array of politicians and local organizations. She is a loyal ally of Donald Trump and a frequent presence on cable TV.
Dominic Thiem takes to the court and slopes in exhibition in Austria
AI in entertainment: The real revolution is operational
Discussions about AI in the entertainment industry often conjure images of algorithm-generated scripts and digitally ... Read More
French President Emmanuel Macron Is Back on Instagram Celebrating Clair Obscur: Expedition 33, This Time for Winning Game of the Year
Clair Obscur: Expedition 33's record-breaking performance at last week's The Game Awards has caught the eye of French president Emmanuel Macron, who celebrated the news of its Game of the Year award on Instagram over the weekend.
Witness describes Hannukah massacre in Australia: ‘It was absolute terror’
Star Trek Fans Need To Watch This Underrated Sci-Fi Series On Peacock
This sci-fi series streaming on Peacock isn't trying to copy the Star Trek franchise, but it should appeal to Trekkies for many of the same reasons.
Dick Van Dyke is 100 years old. Here are his 3 tips for living a long life.
Dick Van Dyke , who celebrated his 100th on Saturday, hasn't shied away from sharing his advice for a long, healthy life.
Kindle’s New AI Feature Can Answer Questions About Your Books (Whether Authors Want It or Not)
The Kindle app's new feature will provide AI-generated tips to explain your book's plot or how the characters relate to one another, though it's currently only available on the iOS version.
Democrat likens Trump’s economic messaging to famous Ron Burgundy moment
Amazon pulls its bad AI video recaps after Fallout fallout
Amazon removed AI-generated video recaps it was testing in Prime Video after viewers noticed errors.
Democrats celebrated Indiana Republicans refusing to redistrict. They’re still moving ahead with their own redistricting push
One day after Indiana Republicans decided to forego political gains by rejecting a new US House map, congressional Democrats made clear Friday they would still press ahead for potential gains in states their party controls.
Roundup: Indiana rejects redistricting, Trump bashes immigrants in Pennsylvania : The NPR Politics Podcast
It’s been a busy week in the political world. We discuss the Indiana state Senate's rejection of President Trump's push to redraw the state’s congressional districts, President Trump's speech on the economy in Pennsylvania in which he denigrated immigrants, and the United States' seizure of an oil tanker off the coast of Venezuela.This episode: political correspondent Sarah McCammon, senior White House correspondent Tamara Keith, and senior political editor and correspondent Domenico Montanaro.This podcast was produced by Casey Morell and Bria Suggs, and edited by Rachel Baye.Our executive producer is Muthoni Muturi.Listen to every episode of the NPR Politics Podcast sponsor-free, unlock access to bonus episodes with more from the NPR Politics team, and support public media when you sign up for The NPR Politics Podcast+ at plus.npr.org/politics.Please let us know what you think of our show and how we can make it better by filling out this quick survey. As a token of our appreciation, three respondents will be randomly selected to receive a $25 gift card.
Who Really Won 2025? The Top-Earning Black Women In Entertainment This Year
From billion-dollar empires to history-making tours, these are the Black women who generated the biggest earnings in entertainment this year.
I visited an underrated city in Sweden before heading to Copenhagen, and it ended up being a highlight of my Europe trip
Malmö, Sweden, is just 20 minutes from Copenhagen, Denmark, via train. Affordable and fun, it's totally worth adding to your trip to Scandinavia.
Ghost particles slip through Earth and spark a hidden atomic reaction
Scientists have managed to observe solar neutrinos carrying out a rare atomic transformation deep underground, converting carbon-13 into nitrogen-13 inside the SNO+ detector. By tracking two faint flashes of light separated by several minutes, researchers confirmed one of the lowest-energy neutrino interactions ever detected.
Omaha business owners frustrated by Streetcar construction
An open house held by the city at the Durham Museum tonight to answer questions about ongoing streetcar construction, but what business owners want is solutions.
Steve Moore on redistricting: ‘Politicians shouldn’t choose voters, voters should choose politicans.’
Dayton RollHouse reopens with new entertainment space
DAYTON, Ohio (WDTN) – RollHouse celebrated the grand reopening of its fully renovated Dayton location on Thursday, Nov. 11. RollHouse is known for blending authentic local hospitality with premium …
Recent Trends in Commercial Health Insurance Market Concentration
Commercial health insurance markets remain highly concentrated across coverage types. However, the individual market, which consists mostly of the ACA Marketplaces, has attracted more insurers and witnessed greater insurer competition across a variety of measures since the implementation of the enhanced premium tax credits in 2021, according to a new Healthy System Tracker analysis.
The New WHO Pandemic Treaty and Global Health Governance: Incorporating Common but Differentiated Responsibilities into PABS - Georgetown Journal of International Affairs
On May 20, 2025, the World Health Assembly unanimously adopted the World Health Organization (WHO) Pandemic Agreement, an international treaty designed to strengthen pandemic prevention, preparedness, and response. The product of three years of arduous negotiations, the treaty marks a new era of global cooperation in public health. However, core aspects of the agreement remain unresolved—notably the Pathogen Access and Benefit-Sharing (PABS) System, which is intended to ensure equitable access to pandemic-related materials and benefits. To support the successful implementation of the WHO Pandemic Agreement, the principle of “common but differentiated responsibilities” should be formally incorporated into the negotiating agenda of the PABS annex. Introduction For the first time, an international treaty has enshrined the principle of “One Health,” the compelling idea that the health of animals, humans, and the environment all contribute to pandemic risks. SARS (2003), H1N1 (2009–10), Ebola (2014–16), and COVID-19 all emerged through zoonotic spillover from animal hosts—respectively, civets, hogs, and bats. Together, they underscore the need for a coordinated, cross-sectoral approach. The Pandemic Agreement responds to this call, requiring state parties to acknowledge the ecological interplay and commit to a comprehensive “One Health” strategy. Specifically, Article 5 charges governments to address “the drivers of pandemics and the emergence and re-emergence of infectious disease at the human-animal-environment interface,” including wild animal markets, deforestation, and antibiotic overuse. Yet the effectiveness of this “One Health” vision depends equally on the free flow of scientific information and data among countries and institutions. Just as environmental and animal health factors have been neglected in past global frameworks, so too has data sharing been marginalized, despite its centrality to timely detection and response. The Pandemic Agreement takes an important step by requiring governments to enhance data collection and cooperate with the World Health Organization (WHO). However, these provisions will remain aspirational without a robust Pathogen Access and Benefit-Sharing (PABS) annex. The PABS system will determine whether countries and researchers can rapidly exchange pathogen samples and genetic data while ensuring equitable access to resulting research and development, including diagnostics, therapeutics, and vaccines. Without such mechanisms, the treaty’s promise to operationalize “One Health” and strengthen global preparedness will risk becoming largely symbolic, echoing earlier failures to translate shared principles into coordinated action. Equity Concerns When the 2025 Health Assembly adopted the Pandemic Agreement, it left the difficult question of access to pathogens and the sharing of resulting benefits to be addressed in a separate agreement. Negotiations on this separate agreement, PABS, are now underway in Geneva. Yet governments remain divided over fundamental questions of equity between the countries that primarily contribute to the system and those that primarily draw from it—and consequently benefit. For example, wildlife in countries bordering the equator is likely to produce PABS materials, but companies in Europe are likely to use them to develop lucrative products. The most likely contributor countries are likely to be those biodiverse countries around the equator, such as Brazil, the Democratic Republic of the Congo, and Indonesia, where the number of human-mammalian viral host interactions is large. Conversely, countries most likely to benefit from this material are those with the technology, investors, and infrastructure to capitalize on genomic data, such as the United States, EU member states, and Japan. This imbalance reflects a broader pattern seen in prior international frameworks. Now, as in the past, the wealthiest countries in the world (a useful heuristic is membership of the Organisation for Economic Co-operation and Development (OECD)) disproportionately benefit from systems in which pathogens and genomic sequencing data are contributed to a common source. Under the International Agreement on Plant Genetic Resources for Food and Agriculture (the “Plant Treaty” or “Seed Treaty”) and the Pandemic Influenza Preparedness (PIP) Framework, companies from Europe and North America disproportionately withdraw biological samples and data for development into lucrative medical products. Their governments and companies have both statutory and contractual claims to the products that those companies correspondingly produce. PABS appears poised to follow the same pattern. The text calls for strong language on access to pathogens and associated data, but the corresponding benefits that should flow to poorer countries are couched in equivocal or non-binding language. Common but Differentiated Responsibilities To address these inequities, the principle of “common but differentiated responsibilities” should be formally incorporated into the negotiating agenda of the PABS annex. Common but differentiated responsibilities are often a feature of climate change negotiations. The basic principle is that, even though all countries should reduce carbon emissions, governments that became rich and powerful through massive carbon emissions (e.g., France, the United Kingdom, the United States) should have a greater obligation to address the resulting crises. Applied to PABS, it would require that governments hosting and supporting companies developing lucrative products carry greater obligations toward the cost of running the PABS system; share benefits or final medical products; and transfer technology to help countries worldwide develop their own capacities to innovate and manufacture vaccines during an emergency. For example, an annex could mandate that any company based in an OECD country that withdraws PABS material would be obligated to donate the resulting diagnostics, therapeutics, or vaccines to the WHO during a public health emergency or pandemic. Questions remain about how robust those donations would be, but the principle is that they should deliver highly significant lifesaving benefits to be equitably shared. Theoretically, this approach mirrors the PIP Framework, in which companies withdrawing influenza samples are required to pay half of the operating costs. In practice, however, the framework has fallen short. The PIP Framework Secretariat has struggled to secure payments from companies, with companies often disagreeing over how much is owed. Additionally, without another pandemic influenza to test the strength of the agreement during a public health emergency, corporate compliance with sharing mechanisms remains unknown. Even if these limitations did not characterize the PIP Framework, partially paying for operating expenses does not address the inequity in access to genetic data and pathogen samples that left less developed countries last in line for COVID-19 vaccines (and, before them, H1N1). Common but differentiated responsibilities would go further, addressing governments’ legitimate grievances regarding information sharing. It would make withdrawals of PABS material and resulting products more transparent, building trust across the board. Enforcement and Enduring Success A key implication of this approach is that the governing mechanism of the PABS must have real enforcement authority. The WHO Pandemic Agreement delegates its core governance responsibilities to a Conference of the Parties (COP)—a governing body composed of one representative from each participating government, similar to those established under the UN Framework Convention on Climate Change and the WHO Framework Convention on Tobacco Control. The proposed WHO Pandemic Agreement COP is charged with oversight functions but ultimately possesses no real authority to compel a government to take any action it does not wish to take. The text does not give the COP the ability to, for example, sanction a party that does not comply with either textual obligations or PABS provisions. In other words, there are no effective mechanisms in place to ensure compliance. Perhaps just as significant, establishing a meaningful enforcement mechanism within the PABS system would strengthen the WHO’s credibility and its ability to ensure compliance across global health governance. By setting a precedent for accountability, such a mechanism could enhance the organization’s authority not only within the Pandemic Agreement but also in enforcing the revised International Health Regulations and other frameworks for public health emergencies. Conclusion The PABS annex can—and should—be different. It should establish clear responsibilities for funding as well as for sharing the diagnostics, therapeutics, and vaccines that result from contributions to the system. The system, in turn, must include a dedicated body empowered to hold governments and the corporations they sponsor accountable for their responsibilities before, during, and after pandemics. Doing so would restore trust in the broader agreement, which was eroded as commitments were repeatedly diluted while parties scrambled to meet their own self-imposed deadlines during the Pandemic Agreement negotiations. A robust PABS Annex would cement a grand social bargain. Wealthier countries and their corporations would gain unimpeded access to scientific information essential for developing and manufacturing lifesaving medical products. As such, they would stand to gain considerable economic benefit. Yet that privilege must be matched with responsibility. The grand bargain must include not only the right to innovate, but also the duty to ensure that innovation serves all. As medical products are developed and produced through collective contributions, every person must have equal access. All human beings deserve an equitable chance to survive—to save their own life, the lives of their families, and the well-being of their communities. … Sam Halabi, JD, MPhil, is the Bette Jacobs Endowed Professor at Georgetown University’s School of Health and the Director of the Center for Transformational Health Law at Georgetown Law. He serves as the co-lead for the WHO’s Working Group on Regulatory Consideration on AI and Health’s training workstream. He earned his JD from Harvard, his MPhil from Oxford, and undergraduate degrees from Kansas State University. Lawrence Gostin, LLD (Hon.), JD, BA, is University Distinguished Professor and Founding Director and Timothy and Linda O’Neill Professor of the O’Neill Institute for National and Global Health Law. He is the author of Global Health Security: A Blueprint for the Future (Harvard University Press, 2021); Global Health Law (Harvard University Press, 2014); Public Health Law: Power, Duty, Restraint (University of California Press, 3rd ed., 2016); Public Health Law and Ethics: A Reader (University of California Press, 3rd ed., 2018); Law and the Health System (Foundation Press, 2014); Principles of Mental Health Law & Practice (Oxford University Press, 2010). He also directs the WHO Collaborating Center at Georgetown University. Image Credit: United States Mission Geneva, CC BY 2.0, via Wikimedia Commons
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