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Arkansas’ September nonfarm job numbers hit a record high
A 1% gain in the number of nonfarm payroll jobs and a more than 8% decline in the number of unemployed helped push Arkansas’ jobless rate to 3.9% in September,...
Panthers playmaker earns Week 6 game ball from CBS Sports
Panthers RB Chuba Hubbard earned some much-deserved recognition for his strong Week 6 performance.
As Summer Crowds Fade, Keystone Businesses Navigate the Annual Shift to Winter
After a summer defined by packed streets, Fourth of July festivities, and celebrations marking America’s 250th anniversary at nearby Mount Rushmore, the tourist hub of Keystone is settling into its quiet off-season
New 6-bedroom house tops sales report at $2.4M
Here’s a look at the top 10 home sales for the week of Sept. 28 in Minnehaha and Lincoln counties.
New Stockton-ACIT Partnership Creates Buzz About Bees
Levine, Gormley Foundations support drone work to study blueberry pollination
Jauan Jennings Trade: Raiders, Vikings Connected In Rumor
Jauan Jennings has not lived up to expectations with the Minnesota Vikings, and the team could part ways with the veteran receiver before the trade deadline. A seventh-round pick in the 2020 NFL Draft, the Tennessee product spent his early years in a supporting role before earning more snaps later in his career. He first …
Engling plans to sue Bayh for defamation in secretary of state race over 'reckless' claim
After the Bayh campaign rebuffed Engling's call to retract and correct a campaign attack ad, the Republican says he's filing a defamation lawsuit.
Smucker, Mannion to go head to head in debate this Friday
Republican Congressman Lloyd Smucker and Democratic challenger Nancy Mannion will debate Friday afternoon at a forum hosted by the Lancaster Chamber and York County Economic Alliance.
Prince Harry reveals real reasons for UK return
LONDON – Prince Harry is finally revealing why he returned to Britain.
Dolly Parton's niece now handling Carl Dean's estate
Carl Dean's niece is now handling his estate, following the death of his wife, country icon Dolly Parton.
Comedian Russell Brand anally raped me, woman tells UK trial
By Michael Holden LONDON, Oct 20 (Reuters) - British actor and comedian Russell Brand anally raped a woman who had willingly gone to his house for consensual sex, ignoring her
OpenEvidence's JAMA paper leaves open questions
In this edition of STAT Health Tech: A new paper in JAMA offers a glimpse into clinicians's use of OpenEvidence, and a look at Isomorphic Labs.
York County Mexican restaurant fails state health inspection
The state Department of Agriculture conducts annual inspections of food-serving businesses to ensure public safety and safe food-handling practices. Schools are inspected twice per year, according to the Bureau of Food Safety and Laboratories.
Lions Named Trade Fit for Chargers’ Young Defender
The Los Angeles Chargers are sitting at 0-6 and likely to be sellers at the trade deadline. After Dave Birkett of the Detroit Free Press suggested the team call the Chargers for cornerback Tarheeb Still or Donte Jackson, Mike Payton of A to Z Sports suggests the Chargers’ other cornerback is the best fit of […] The post Lions Named Trade Fit for Chargers’ Young Defender appeared first on HEAVY.
Giants release veteran linebacker after just 2 games
Giants quickly move on from Jihad Ward after two unimpressive games.
Patriots News: Vrabel – ’Everybody prepares as a starter’
Daily news and links for Tuesday, 10/20/26
Feeling overstimulated in public? Mental health experts share the strategies that work in any situation
Sensory overload can hit in a grocery store, on a commute or at a crowded party. Here's what therapists and a Harvard psychiatrist recommend, including a few products worth keeping in your bag.
Now open in South Asheville, Novant Health launches new mammography mobile unit
Novant Health has launched a mobile mammography unit, bringing breast cancer screenings directly to Western North Carolina communities.
Evolution of women’s healthcare focus of URI’s annual Youngken Clinic
KINGSTON, R.I. — Oct. 20, 2026 — Women’s healthcare is evolving rapidly, and while greater emphasis has been placed on comprehensive care, women still face more barriers to healthcare than men, according to the National Institutes of Health. Pharmacists are key players in helping break down those barriers, playing an increasingly important role in improving […]
Amazon plans more than 2,000 holiday hires in Tampa Bay
The online retailer’s nationwide hiring target includes roughly 21,000 employees from Florida, with more than 300,000 nationwide.
Who is Tommy Tuberville? Auburn coach turned governor candidate
From the Auburn sidelines to the U.S. Senate, Tommy Tuberville is now seeking Alabama's top office. Here's what voters should know.
Spotify pulled 50 million AI slop and spam tracks from its recommendations
Spotify still isn’t labeling AI tracks, though.
Abbott, Big 10 Conference, Rutgers Athletics, and RWJBarnabas Health Seek to Boost National Blood Supplies
Diego Orozco knows firsthand that every blood donation offers new hope for blood cancer patients like him. After battling leukemia and enduring three stem cell transplants, the 34-year-old North Plainfield resident has relied on countless blood transfusions to survive some of the most difficult moments of his cancer journey.
Understanding Intelligence Across Artificial and Biological Systems
Recently I started a new peer-reviewed journal at the crossroads of Artificial Intelligence and Cognition research. The journal, titled "AI and Brain", is published by Scilight Press, a young
Paxton campaign showing ‘desperation’ with manufactured story: Political commentator
In the final days until election, President Trump is set to hold another rally in Texas for Republican Senate candidate Ken Paxton. MS NOW National Reporter Rosa Flores shares what she is hearing from voters there. MediasTouch Journalist Adam Mockler, Democratic Strategist Basil Smikle, Bloomberg Businessweek Journalist Max Chafkin, and Rolling Stone Magazine Politics Reporter Nikki McCann Ramirez join the Group Chat with Stephanie Ruhle to share their analysis.
New Apple TV 4K Features 'Whole Room Audio' With Four HomePods
The new fourth-generation Apple TV 4K announced last week can connect to up to four HomePods in front-left, front-right, rear-left, and rear-right positions, enabling an all-Apple surround sound system for home theater setups. There is also a related new feature that has not received as much attention: Whole Room Audio. Apple says the Whole Room Audio feature spreads sound evenly across four HomePods in a room.
JD Vance declines to endorse Netanyahu for reelection, says he's focusing on midterms
“I endorse American candidates, and that’s where I’m focused on the midterms,” Vice President JD Vance said.
Green Science Alliance opens Swiss battery recycling lab
The Japanese chemical and greentech firm has opened a battery recycling laboratory at the Switzerland Innovation Park Biel/Bienne (SIPBB) in the canton of
Prenosis and Carle Health Mark Sepsis ImmunoScore® Clinical Deployment and First Patients Enrolled in OBSERVE-ARDS Clinical Study
/PRNewswire/ -- Prenosis®, a biology-based technology company delivering precision therapeutics, today announced three milestones in its ongoing relationship...
Morning 3: Lincoln County home health worker accused of taking thousands in forged checks -- and other news
Here are the top stories for the morning of Oct. 20, 2026
Christina Applegate says she’s ‘scared’ after MS misdiagnosis: ‘I feel lost’
Christina Applegate said on Tuesday’s episode of her ‘MeSsy’ podcast that she is feeling ‘lost’ after being misdiagnosed with multiple sclerosis for years.
Every Mother Counts Board Visits With UAMS Institute for Community Health Innovation, Ignite
Members of the Every Mother Counts Board of Directors recently visited the University of Arkansas for Medical Sciences (UAMS) Institute for Community Health Innovation and Ignite Professional Studies and saw first-hand how community leaders are paving the way to improve maternal health outcomes in Arkansas. Founded by Christy Turlington Burns,…
Home health worker accused of taking thousands in forged checks in Lincoln County
The employee allegedly took checks from a checkbook while providing care at a patient’s house.
Wire 3 Begins Construction on Easley Expansion
Wire 3, a leading 100 percent fiber internet provider, announced that construction is underway in Easley, marking another step in the company’s South Carolina expansion. Powered by a fully funded $19 million investment, the Easley expansion will...
Hartford names wholesale, financial lines leaders
The Hartford on Tuesday named Charles Chin head of wholesale casualty for its Navigators unit and Anthony Dolce head of financial lines, U.S. and global practice for its global specialty business unit.
MCG and Itiliti Health Form Partnership to Support Health Plans with CMS-0057-F Compliance
/PRNewswire/ -- MCG Health, part of the Hearst Health network and the industry's source of truth for trusted clinical guidance, today announced a strategic...
Trumbull Health Department Holding Walk-in Flu Clinics This Week
The Trumbull Health Department will be having walk-in flu clinics this week:TODAY, 10/20/27: 10-12pm and 2-4pmWednesday, 10/21/26: 6-8pm 335 White Plains Road No appointment required!We will
Bush family royalty backs Democrat in battle to flip Texas blue
Barbara Bush donated $2,500 to a PAC supporting James Talarico's Texas Senate race against Ken Paxton, using her real name in public FEC filings.
Houston voters welcome long lines as early voting begins
For some voters, participating in the election also meant encouraging others to do the same.
Looted French goods are popping up on resale site Vinted
The second-hand online marketplace Vinted has removed listings of looted French goods and stepped up checks on “suspicious” adverts, as the country’s authorities seek to prevent goods stolen during riots from being sold online.
Echo Electric opens Sioux Falls facility
Echo Electric, a Sonepar company and full-line electrical distributor, has opened a location in Sioux Falls.
Christina Applegate Says She Was Misdiagnosed With MS After Yearslong Battle
Years after Christina Applegate shared that she was battling multiple sclerosis, the actress said she is "back at square one" after learning she had been misdiagnosed.
Today’s Papers: Juventus faith in Spalletti, Milan in Krösche talks
La Gazzetta dello SportSpalletti on the edgeThe coach has lost his way at Juve: Faith for the time beingDisastrous start, no lifelines left. A nervous coach asks for clarifications from Bremer. The su...
Docktober invites folks to join citizen scientists in peeking under docks
Oregon naturalist leads the global Docktober movement, encouraging citizen scientists to discover and document the marine life thriving beneath public docks.
'Office Space' star Richard Riehle dies at 78
Actor Richard Riehle arrives at the premiere of New Line Cinema's 'A Very Harold & Kumar 3D Christmas' at Grauman's Chinese Theatre on November 2, 2011 in Hollywood, California. (Jason Merritt/Getty Images)Richard Riehle, known for his role in the 1999 film Office Space, has died. He was 78.A statement shared by Artists & Representatives and Wright Entertainment, Inc. announced Riehle's passing on Monday, writing, "Our industry has lost an exceptional talent, and our community has lost a truly wonderful man.""We are deeply saddened to confirm the passing of our beloved client, Richard Riehle, this past weekend," the statement said. "A remarkable actor whose career in theater, film, and television spanned nearly five decades and more than 400 projects, Richard leaves behind an extraordinary legacy."The statement continued, "Beyond his immense talent, he will be remembered for his genuine goodness, boundless kindness, and unwavering generosity, particularly toward emerging actors and filmmakers, whom he encouraged and supported at every opportunity."Born on May 12, 1948, Riehle starred in many television series and films over the years.Notable projects include Casino, The Man from Earth and Deuce Bigalow: Male Gigolo.He got his start as an actor at the University of Notre Dame, where he was involved in the University Theatre and starred in several stage productions. He went on to earn a Master of Fine Arts in acting and directing from the University of Minnesota.While he's played characters that have an "average Joe" presence, he always made the most of his brief screen time.Some roles that he is remembered for include The Quartermaster in Glory, the train guard in The Fugitive, Reverend Scroggins in Fried Green Tomatoes and Bill Cozbi in Bridesmaids.On television, he starred as Principal Ed Rooney in the 1990 series Ferris Bueller and as grandfather Walt Finnerty in the early 2000s sitcom, Grounded For Life.In 2023, he also played Warden Reynolds in Barry.Riehle is survived by his wife, Jane Latham, and their four children.Copyright © 2026, ABC Audio. All rights reserved.
Xbox is struggling for stock so bad that it's encouraging lapsed users to trade-in their dormant consoles ahead of GTA 6
The console stock situation is so dire now that Microsoft is targeting lapsed users with second, dormant Xbox consoles to recommend trading-in. The RAM crisis continues.
Revisiting Brewers' Adames Trade Which Included Rays' Rasmussen
The Milwaukee Brewers transformed their infield with a midseason swap, but the Tampa Bay Rays struck gold by turning a struggling reliever into a dominant ace.
Small Business Administration Opens Nominations for Small Business Week Awards
The U.S. Small Business Administration (SBA) and the South Carolina District Office opened nominations for its 2027 National Small Business Week Awards, which recognize exceptional small business owners from South Carolina. National...
Planning commission lauds work on ‘complex’ Lake Fairfax Business Center development plan
Plans to transform most of the Lake Fairfax Business Center in Reston into a mixed-use neighborhood are heading to the Fairfax County Board of Supervisors for a final vote. Developer EYA secured a supportive recommendation from the Fairfax County Planning Commission last Wednesday (Oct. 14) after its legal representative confirmed that any lingering disagreements with
Alexa Tablet 12 Pro Review: Amazon Comes Out Swinging At The iPad
Amazon's Alexa Tablet 12 Pro is an entirely different beast than the Fire tablet lineup, and its more premium build and specs make it a legit iPad competitor.
KFF Tracking Poll on Health Information and Trust: Fall 2026 Update on Vaccine Views
The latest KFF Tracking Poll on Health Information and Trust finds about half of parents mistakenly believe spacing out vaccines is healthier for children, while confidence in many long-standing childhood vaccines is high across partisans. These findings take on new relevance following President Trump's recent executive order calling for changes in U.S. childhood vaccine recommendations, including splitting the measles, mumps, and rubella (MMR) vaccine—currently given as a single combined shot—into three separate vaccines across multiple visits.
Beyond Moneyball: What the Milwaukee Brewers Can Teach Businesses About Teamwork
The Milwaukee Brewers’ sweep of the defending champion Los Angeles Dodgers stunned the baseball world. But the series also showed that assembling the biggest collection of stars isn’t the only path to success, says University of Delaware researcher Kyle Emich. The Brewers' run to the World Series – which continues this week against the Tampa Bay Rays – demonstrates how a team can combine its strengths, adapt to an opponent and operate as a system, Emich says. That same p
Bill Clinton and David Jolly to hold campaign event in Hollywood
They will hold the campaign event at 6:30 p.m. on Tuesday.
Trump continues midterm campaign blitz in North Carolina
President to stump for Michael Whatley, who is facing an uphill battle against Democrat Roy Cooper for the Senate, as elections are just two weeks away
North Carolina Could Play a Key Role in This Year’s Midterm Elections, Wake Forest Expert Says
Planning TB prevention: Considerations for an evolving toolkit
Explore our TB prevention toolkit: today’s tools, the pipeline of new options, and the open questions ahead.
COD Black Ops 1 and 2 dev says it’s ‘hard to watch’ the new ports selling well while ‘the actual creators don’t see a dime’
Activision and Microsoft are “printing money off of work completed over a decade ago”…
Scientists finally uncover why statins can cause muscle pain
Scientists have uncovered a surprising reason why statins, the widely prescribed cholesterol-lowering drugs that help prevent heart attacks and strokes, can sometimes cause muscle pain, weakness, and even severe muscle damage. Using advanced imaging technology, researchers discovered that statins can attach to a crucial protein in muscle cells and force open a channel that normally controls calcium flow. This causes calcium to leak continuously, potentially damaging muscle tissue.
CA immigration business seized over allegations of practicing law without a license
The State Bar of California raided the North American Immigration Center in Chino, calling it an unauthorized law firm
Tailored to Your Trade: Inside the New Small Business Credit Card Lineup on the Amex Network
Tailored to Your Trade: Inside the New Small Business Credit Card Lineup on the Amex Network
Study links rise in online sports betting to mental health issues
The study’s authors said gambling and sports betting have never been more accessible.
Sponsored Content: HMG Health Matters: A Surgeon's Perspective on Breast Cancer
Dr. Cheryl Stanski, General Surgeon and Vice President of Holston Medical Group tells us what she wants every woman to know about breast cancer. She talks about the success rate, the hope, and the options now available for women. For more information and to read more please visit the Health Matters blog at HolstonMedicalGroup.com.
How Much Of Cisco Stock's Rise Did The Business Earn?
Cisco Systems (CSCO) supplies businesses and the hyperscalers building AI infrastructure with networking and security products, along with services. The company's stock climbed 92% between late July 2021 and mid-October 2026, before dividends. A rally of that magnitude makes it natural to credit a growing business. So take a guess: how much of that rise came from Cisco selling more.
SBA urges Iowans to nominate their favorite small business for an award
There are all kinds of small businesses in Iowa that we can’t do without, from diners and donut shops to tailors and auto mechanics, and it’s time to recognize those merchants that make our lives better. Ryan Lincoln, the Iowa district director of the U.S. Small Business Administration, says the agency is taking nominations for […]
United CEO Scott Kirby calls for wealth tax and a near-100% inheritance tax
United Airlines CEO Scott Kirby says wealth inequality threatens society and calls for a national wealth tax and steep inheritance taxes.
Brightstar Capital Partners Invests in Material Handling Group, a Technician-Led Provider of Material Handling Equipment and Aftermarket Services
CANTON, Mich. & NEW YORK, October 20, 2026--Brightstar Capital Partners ("Brightstar"), a private equity firm focused on partnering with founders, entrepreneurs, and management teams, has acquired a majority interest in Material Handling Group USA ("MHG" or the "Company"). Financial terms were not disclosed. MHG is a technician-led provider of new, used, and rental material handling equipment and aftermarket parts and service, serving customers across Michigan, New York, and the Mid-Atlantic reg
A note to readers: Science, accountability and elections
Dear readers, As early voting begins, I wanted to share some news — and why it connects to the decisions we make at the ballot box. I’ve been selected for the inaugural cohort of the South Atlantic Climate Journalism Hub mentorship program, hosted by Covering Climate Now. I’m excited to join this group, learn from scientists and fellow journalists, and expand my science reporting. Science directly ties to governance. Local officials make decisions about where development goes, how infrastructure is maintained, what emergency preparations receive funding, and how communities rebuild after disasters. Understanding the evidence behind those decisions helps us evaluate whether our government is serving us well. Here in western North Carolina, those connections are all around us, in Lake Lure and beyond. Flood maps inform decisions about property and development. Engineering assessments help identify risks at dams and bridges. Rainfall forecasts guide emergency preparations. Geological information helps explain landslide hazards. Water testing gives communities information they need to assess conditions. Meteorologists’ knowledge and public perception of weather events shape public safety. Each involves scientific or technical knowledge. Each also raises questions about public responsibility: What did officials know? How did they use that information? What did they tell the public? What did taxpayers receive for their money? A study can identify a problem. Elected officials still have to decide what to do about it, how to pay for it, and how to explain their choices. Reporting should examine both the evidence and the response. That is where I want to strengthen my work. My reporting on Helene recovery, infrastructure, flooding, public safety, and public spending has repeatedly brought me to questions that require scientific expertise alongside public records. This mentorship may help me better understand the research, ask more precise questions, and explain the answers clearly. I also bring the perspective of someone living with these concerns. I live downstream of Lake Lure Dam, and landslides affected my property during Helene. Those experiences bring urgency to my questions. Careful reporting helps establish the answers. Readers deserve to know what the evidence shows, where uncertainty remains, and whether officials accurately describe the information guiding their decisions. You also deserve scrutiny of proposed solutions: what they cost, what they are expected to accomplish, and what risks remain. Access to that information matters. As a mostly deaf journalist who relies on written communication, I will continue pressing for written public warnings, records, and explanations that people can read and use in real time. As you consider the candidates seeking your vote, consider how they approach evidence, preparedness, and transparency. Do they support local journalism, even when it’s not parroting a press release? Do they explain weather events clearly in plain English and explain their decisions after them? Make supporting records available? Acknowledge uncertainty? Follow through when a report identifies a risk? Those are practical questions about governing. Thank you for supporting Cops & Congress and the work that makes these questions part of the public conversation. I’m grateful to David Dickson and the CC Now team for this opportunity, and I look forward to bringing what I learn back to you. Annie DanceEditor & Publisher, Cops & Congress — Learn more about this newsletter, ethics policy, how you can help shape this work, and support it. Follow on X and Facebook. Send constructive criticism, fan mail, and tips with public documents for future stories: CopsandCongress@gmail.com ICYMI: View the Cops & Congress archive — Annie Dance is the publisher of Cops & Congress, a newsletter that analyzes what happens when crime, courts, disaster, democracy, and small-town policies collide. Views expressed here are covered by the First Amendment. Dance has a Bachelor of Arts from Manhattan University in Communication with a focus in Journalism and Government. She has been a journalist for over 20 years. Share Upgrade now or give a gift subscription
Bill Nye "The Science Guy" makes surprise appearance in Rutherford County
Nashville News, Weather, and Sports
'The Simpsons' resurrects Apu after nearly a decade of silence
The Halloween-themed episodes of “The Simpsons” have always been a treat of spooky stand-alone storylines. On Sunday, the show surprised viewers with the resurrection of Apu. The beloved Indian Kwik-E-Mart
‘The Simpsons’ revives Apu following years of controversy
Across 38 seasons of “The Simpsons,” the Halloween-themed “Treehouse of Horror” episodes have always been a treat of spooky stand-alone storylines. On Sunday, the show surprised viewers with a majo…
SpaceX earnings put Elon Musk's Starlink cash cow to the test
Elon Musk is taking a big swing in his bet to turn Starlink into a mobile carrier just in time for earnings.
Green Bay Packers add former first-round pick amid defensive line injury concerns
The Green Bay Packers are searching for defensive line help after injuries weakened their options up front. With starting nose tackle Javon Hargrave out, veteran Chris McClellan is expected to fill the role, but Green Bay has limited depth behind him. To strengthen the rotation, the Packers have signed a former first round pick to [...]
Uzbekistan's $12bn business drive gathers pace during Rubio visit
The package covers railways, critical minerals, finance and technology, with major US firms involved. Uzbek President Mirziyoyev outlined measures to attract investors, while business executives told Euronews that commercial activity is growing.
What to know about the two candidates in Wisconsin's 7th District
Republican Michael Alfonso and Democrat Fred Clark are squaring off in the 7th Congressional District. The winner will succeed Tom Tiffany.
‘A huge need’: Free healthcare day event draws hundreds to Charleston clinic
More than 400 people got medical, dental or vision care at a one-day free health care event in Charleston, West Virginia on Saturday.
LACMA, Perrotin, the new Metro and now the Brick: Todd Gray is having a banner year
Todd Gray has a solo show opening at the Brick on Oct. 18 — the cap on a banner year including a LACMA commission, a solo show at Perrotin and a public art piece for the Wilshire/La Cienega station for the D line.
How one health system is battling rising uncompensated care costs
Sanford Health is expanding patient navigation and Medicaid renewal support as uncompensated care costs rise and more patients lose coverage.
The Data Dive: Steve Kornacki on how Susan Collins could transcend Trump in Maine
Seeking re-election in a blue state, the longtime Republican senator is relying on her personal brand to defy political gravity — again.
List of DVD release dates for Oct. 20 and beyond
Following is a partial schedule of coming movies on DVD. Release dates are subject to change: OCTOBER 20: Masters of the Universe 20: Hadestown: The Musical 20: One Night Only
Why Calling Anti-Trans Hate a “Distraction” Is So Troubling
It’s a familiar line in the midterms: Anti-trans attacks are a “distraction” from “kitchen-table” issues. That sends a chilling message about whose rights are worth fighting for.
What Is Culinary Medicine? Bridging Nutrition, Cooking, and Health
Culinary medicine combines nutrition science with practical cooking education to help patients apply dietary advice and train healthcare professionals in nutrition counseling. Studies report improvements in cooking confidence and dietary behaviors, but evidence for sustained clinical benefits remains limited.
Republicans in competitive Pa. races are tying themselves to Josh Shapiro. What does that mean for the midterms?
Republicans in competitive swing district races are featuring Gov. Josh Shapiro in ads. It's "quite telling," one political science professor said.
Vivek Ramaswamy gets a political education in a grueling Ohio governor’s race
Vivek is attempting a rare route in politics, going from national notoriety as a presidential candidate to running for state office, eschewing his hard-charging and provocative tone during his presidential campaign. He’s making his pivot during an election cycle where headwinds are blowing against all kinds of Republicans. It hasn’t been easy.
JCPS paid $292K for an online mental health service. Six kids used it.
The company is one of hundreds of ed tech providers that have contracted with JCPS
Garland County Master Gardeners’ October Business Yard of the Month goes to Belvedere Nursing and Rehab
The Garland County Master Gardeners chose Belvedere Nursing and Rehab, 2600 Park Ave., as its October Business Yard of the Month, according to a news release.
Bigfoot to Bojangles: How a Charlotte family built a business on make-believe
Long before the store became a Charlotte fixture, it started with a phone call, a rack of costumes and a couple willing to take a chance.
Threats of political violence soar in Australia’s ‘online echo chamber’
Independent lawmaker Helen Haines was in critical condition after being struck deliberately by a car.
Manchester United and Liverpool battling for Borussia Dortmund star
Manchester United and Liverpool are both considering a move for Borussia Dortmund midfielder Felix Nmecha, according to TEAMtalk.The report suggests that Manchester United have made contact as they as...
PREVIEW: Wolves face Portsmouth for the first time since 2010
Portsmouth will travel to Molineux on Tuesday evening for the first time in 17 years to face Wolves in a rescheduled Championship fixture.With a game in hand, a win for Cesar Peixoto’s side will see...
Final Fantasy Resonance Review: On Its Own Wavelength
Final Fantasy Resonance (Switch 2) Review – 9/10: It may have one foot planted in the series' history, but in a time when mainline Final Fantasy is still figuring itself out, Final Fantasy Resonance is easy to recommend. - Game Informer
Banijay Confirms Senior Leadership Structure
The newly-minted Banijay Entertainment has set out its senior leadership team following the merger with All3Media.
Sandpoint Furniture honored as top chamber business
Sandpoint Furniture earned October Business of the Month honors from the Greater Sandpoint Chamber of Commerce, recognizing more than 80 years of service, community involvement and growth in the Sandpoint area.
Pfizer makes ‘business decision’ to end phase 2 trial of autoimmune drug as program’s future uncertain
Pfizer has called time on a phase 2 trial of its CXCR5 antibody in an autoimmune blood disorder, with the company tight-lipped on whether this marks the end of the road for the asset. The Big Pharma had been evaluating the therapy, dubbed PF-06835375, in a phase 2 study of 61 patients with primary immune thrombocytopenia (ITP) that kicked off in 2022, according to the federal trials register. However, Pfizer confirmed to Fierce on Monday that this study had been terminated “due to a business decision.” “The decision to terminate the trial was not based on any safety concerns,” a spokesperson pointed out. At time of publication, PF-06835375 remained listed on Pfizer’s website for both ITP and lupus. A phase 1 study in lupus wrapped up in 2022, according to the trials database. ITP is an autoimmune disorder characterized by a low platelet count. Novartis was at one point evaluating its B-cell-depleting antibody ianalumab—recently approved as Fabhalta to treat immunoglobulin A nephropathy—as a potential treatment ITP. But the therapy struggled to demonstrate a benefit in the clinic for this indication. When contacted by Fierce, Pfizer wouldn’t confirm whether all work on PF-06835375 has been halted, and whether the company has any other plans to explore C-X-C chemokine receptor type 5 (CXCR5) as a mechanism. CXCR5 is found in blood cancers such as diffuse large B-cell lymphoma and mantle cell lymphoma chemokine receptor. However, there is little expression in normal tissue, which has led some drug developers to explore its potential. Vincerx Pharma had at one point been planning to take an anti-CXCR5 ADC into the clinic to treat B-cell malignancies, but that ambition was scrapped due to cash constraints. Where Big Pharma is placing its bets is one of the hot topics being discussed at Fierce Biotech's high-impact event in London next month. Find out more information and register by clicking on the banner below: [ ](https://qtxasset.com/quartz/qcloud5/media/image/where_big_pharma_is_placing_its_bets.png?VersionId=B8JrRbJ.pFUSK1pJgjeWHLGm_18RdLAy)
GLP-1 drugs may protect kidney health in people with bipolar disorder
Mayo Clinic researchers found that GLP-1 receptor agonists, medications widely used for diabetes and weight management, were associated with a lower risk of dialysis or kidney transplantation in adults with bipolar disorder and chronic kidney disease.
9,450 Shares of Live Nation Entertainment, Inc. $LYV Bought by Cordatus Wealth Management LLC
Cordatus Wealth Management LLC acquired a new stake in shares of Live Nation Entertainment, Inc. (NYSE:LYV - Free Report) during the 3rd quarter, according to the company in its most recent 13F filing with the Securities & Exchange Commission. The institutional investor acquired 9,450 shares of
🗞️ A gala night in Paris: Tuesday's front pages
The front pages of Europe's sports newspapers this Tuesday, October 20, focus on a thrilling day of Champions League action, with the clash between PSG and Barcelona taking centre stage. Meanwhile, in...
Arkansas football commitments excited about win over Vanderbilt
Several Arkansas football commitments liked what they saw of the Razorbacks’ 31-21 road victory over Vanderbilt while ending a 14-game SEC losing streak.