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Voice of America Journalists Sue, Saying Trump Officials Interfered in Coverage
The journalists said in the complaint that the administration was trying to force them to be a “mouthpiece” and that one official demanded “loyalty” if reporters wanted to “keep their jobs.”
Revolutionary Submarine Mysteriously Disappears Without a Trace – Scientists Are Now Preparing for a Bold Return
A pioneering robotic submarine that explored beneath Antarctica’s glaciers has been lost, but its discoveries are reshaping our understanding of ice melt as a more advanced successor is prepared to continue the mission.
Cycling, crystals and cutting-edge science: the secrets of Hodgkinson and Hunter Bell’s success
The training duo who oversaw famous medal success in Torun believe the best is yet to come for their athletes
Today's hefty Crimson Desert patch includes "beginning of improvements" to keyboard and mouse controls, plus much more
Pearl Abyss has detailed a rather chunky patch for Crimson Desert, after its launch last week was marred by multiple issues and AI controversies.
Business closed after new Ohio law banning intoxicating hemp products went into effect
Senate Bill 56 grants law enforcement the authority to remove intoxicating THC products from unlicensed retail locations,
Minnesota Wild, NHL mourn hockey writer Jessi Pierce after death in house fire
Pierce and her three children were killed in a house fire outside of Minneapolis early Saturday morning.
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
‘Trump should keep his reckless mouth shut’: Jeffries responds to Trump calling Democrats America’s ‘greatest enemy’
Titans sign ex-Browns linebacker
The Titans have signed former Browns linebacker Mohamoud Diabate to a contract after he wasn't tendered as an RFA.
A secret weapon to fight carbon emissions was just discovered: Beavers
A new study in Switzerland finds that beaver-built wetlands can trap and store large amounts of carbon, offering a low-cost boost for restoration and climate resilience.
Pompey's hopes of staying up now unsure
BBC Radio Solent commentator Andrew Moon gives his thoughts following Portsmouth's 6-1 defeat at Queens Park Rangers in the Championship.
In the Fight to Defend the Amazon, This Indigenous Community’s Secret Weapon Is Science
In the copper-rich mountains of southeastern Ecuador, Shuar people are combining ancestral knowledge and modern science to protect their forest from a Canadian mining giant.
Eating More Ultra-Processed Foods Could Damage Your Bones. Here's Why
Eating higher amounts of ultra-processed foods is associated with lower bone mineral density and a higher risk of hip fractures, even in younger adults under 65.
The perfect amount of wine to drink to lower your risk of dying from heart disease by 21%
UFC Fight Night odds, lines, predictions, time: Evloev vs. Murphy picks from proven MMA expert
Expert Kyle Marley reveals his UFC Fight Night best bets for the March 21 London card on Paramount+
Farmers and rural community members can access free mental health resources
KGAN CBS 2 and KFXA Fox 28 provide local news, weather forecasts, notices of events and items of interest in the community, sports and entertainment programming for Cedar Rapids and nearby towns and communities in the Corridor and throughout eastern Iowa, including Iowa City, Waterloo, Dubuque, North Liberty, Coralville, Marion, Morengo, Williamsburg, Washington, Tiffin, Tipton, Solon, Mount Vernon, Lisbon, Central City, Urbana, Independence, Manchester, Dyersville, Oelwein, Cedar Falls, Waverly, Evansdale, Guttenberg, West Union, New Hampton, Decorah, Waukon, Maquoketa, Sigourney, Fairfield, Grundy Center, La Porte City, Dysart, Fayette, Elkader, Strawberry Point and Belle Plaine.
Crimson Desert Dev Promises Patch to Address 'Discomfort Many Players Have Experienced With the Controls,' Apologizes for Awful Keyboard and Mouse Experience
Crimson Desert developer Pearl Abyss has issued a message to players addressing complaints around the game’s controls, which have been widely criticized.
Aspen hosts an eve of storytelling with famed sports photographer
Led by the lens, acclaimed American sports photographer Jean Fruth will share tales from her work covering Major League Baseball and beyond.
Hubert Davis' future at North Carolina in serious doubt as pressure mounts after historic collapse
Sources tell CBS Sports that Hubert Davis' future at North Carolina is in serious doubt after a historic NCAA Tournament collapse, with boosters losing faith and questioning their willingness to fund the program.
The surprising ways menopause can affect your mouth — and what you can do about it
UFC Fight Night odds, lines, predictions, time: Evloev vs. Murphy picks from proven MMA expert
Expert Kyle Marley reveals his UFC Fight Night best bets for the March 21 London card on Paramount+
Big money flows into state attorney general races as legal battles shape American politics
There are races in 30 states this year for attorney general, and groups that support those candidates prepared for the elections by raising record amounts in 2025.
Big money flows into state attorney general races as legal battles shape American politics
There are races in 30 states this year for attorney general, and groups that support those candidates prepared for the elections by raising record amounts in 2025.
Giant Study May Have Found The Ideal Amount of Coffee to Lower Stress
There's actually a sweet spot.
Giant Study May Have Found The Ideal Amount of Coffee to Lower Stress
There's actually a sweet spot.
A massive freshwater reservoir is hiding under the Great Salt Lake
A hidden freshwater system deep beneath the Great Salt Lake has been revealed using airborne electromagnetic surveys. Scientists found that freshwater extends much farther under the lake than expected, reaching depths of up to 4 kilometers. The discovery began with mysterious reed-covered mounds formed by pressurized groundwater pushing upward. Researchers are now investigating whether this underground water could help control hazardous dust from the drying lakebed.
The biggest medieval march in English history never actually happened
A famous detail in the Battle of Hastings is based on a major misunderstanding.
Small business and entrepreneurship growth a point of focus for Secretary of State’s Office
LEWISBURG, WV (WVNS) – Entrepreneurs and small business owners in the Mountain State have gotten some extra support with the passage of new legislation. West Virginia Secretary of State Kris Warner me...
The mental health effects of gun violence near schools
Dr. Scott Hadland from Mass. General Brigham discusses new data that shows the amount of shootings near schools is trending downwards.
Police responding to business explosion in Carroll County
According to a spokesperson for the Carroll County Sheriff’s Department, the explosion occurred Friday afternoon at the address of Catoctin Mountain Growers.
Argyle record-breaker Campbell signs first pro deal
Plymouth Argyle's youngest-ever goalscorer Seb Campbell signs his first professional deal with the club.
This Infamous Radioactive 'Tomb' Is Leaking, And Experts Are Worried
"The integrity of the dome could be in jeopardy."
Weymouth teen, dad start birdhouse business Chirp
A Weymouth father and daughter turned a backyard project into a growing business inspired by architecture and family time.
New dispute emerges around Subnautica 2’s early access release
Lawyers for the ousted—and now partially reinstated—leadership team of Unknown Worlds, the studio behind Subnautica 2, are crying foul over news that the game will be released into early access in May. The release announcement earlier this week was made improperly, potentially “damaging the game and sowing additional confusion among the Subnautica community,” the lawyers said in a letter sent on Tuesday to Vice Chancellor Lori Will of Delaware’s Court of Chancery. In their letter, the lawyers also floated the idea of asking Will to find Krafton in contempt of the court’s ruling. The letter was sent just one day after Will’s bombshell ruling that publisher Krafton had breached its contract with Unknown Worlds’ executive team, when it fired them last June. The new issue isn’t necessarily the May early access timeframe, but how the news was announced. The letter and Krafton’s response have not been previously reported. A quick recap of prior events: Subnautica 2 is an unreleased, underwater survival adventure and the most-wishlisted game on Steam. Last year, longtime Unknown Worlds CEO Ted Gill, along with studio co-founders Charlie Cleveland and Max McGuire, were fired by Krafton. They swiftly sued, saying the publisher had terminated them to avoid paying out up to $250 million in potential performance-based bonuses. The studio leaders had hoped to earn that with an early access release of the game, which Krafton had blocked. The publisher argued in court that Subnautica 2 wasn’t ready, which the ousted execs disputed. On Monday, Will ruled that Krafton had violated its contract, firing the execs to avoid the performance payouts, and that it had to reinstate Gill and give him full authority over any early access release for Subnautica 2. On Tuesday, IGN reported on a new memo issued that day to Unknown Worlds staff by Steve Papoutsis, the executive Krafton had put in charge of Unknown Worlds after the 2025 firings. In the note, Papoutsis said that Subnautica 2 had passed a key development milestone “last week” and that he and Krafton had determined the game “is ready for Early Access release in May.” This news appeared to catch the lawyers for Gill, Cleveland and McGuire by surprise. On Tuesday night, they sent a letter to Will expressing “serious concerns” about whether it would be possible to forge an agreement with Krafton consistent with the judge’s order. Papoutsis’ memo was a problem, they wrote. He didn’t have the authority to declare anything about Subnautica 2’s release. As of 9am ET on Monday, March 16, the effective date of Will’s order, Papoutsis wasn’t CEO of Unknown Worlds. Gill was. And, per Will’s order, only Gill could make Subnautica 2 release decisions. They continued: Krafton self-servingly announced the launch without any regard to its impact on the game, the team, or the community—let alone this Court’s Opinion. Announcing the release of a game is momentous, and it is typically accompanied by significant marketing activity, fanfare, and community coordination. And most importantly, the announcement is carefully designed to maximize excitement for the game. That entire process was supposed to be driven by Mr. Gill. However, in defiance of the Court’s Opinion, Krafton has now taken that away, further damaging the game and sowing additional confusion among the Subnautica community. The lawyers speculated that Krafton had “intentionally leaked” Papoutsis’ memo and then issued an official statement to confirm the leak. Game File is a reader-supported publication. My reporting is only possible through support from readers like you. To support my work, consider becoming a free or paid subscriber. Subscribe On Wednesday, lawyers for Krafton defended their client in their own letter to vice chancellor Will, saying nothing they did violated her order nor showed contempt: Papoutsis’s message was simply celebrating the UW employees’ efforts toward a past event: Krafton’s pre-Opinion determination that Subnautica 2 was ready for Early Access release. There was nothing improper about conveying the results of the milestone review or thanking the development team for their dedication and talent. They added that Gill could still make his own call about Subnautica 2’s release: In his role as CEO, Gill will be able to assess independently his views on the state of Subnautica 2 and the appropriate release schedule; nothing in Papoutsis’s message alters Gill’s authority or discretion. Vice chancellor Will has not responded to the letters and doesn’t necessarily have to. Both parties were previously ordered by Will to confer this week and submit a proposed judgment consistent with her ruling. The letter from Gill’s attorney’s this week doesn’t indicate whether he would or would not support a May release for Subnautica 2. But it could limit his options. And, if Gill’s lawyers are right, the lack of marketing fanfare around the leak of the May date could dull the launch of the game. Any harm to Subnautica 2’s launch is an extra sensitive issue given the context of the legal dispute: millions of dollars of payouts are on the line, tethered to the scale of the game’s initial performance. In her ruling on Monday, Will noted that there was obvious “bad blood” between Gill’s side and Krafton but that the two would need to work together: “They can—and must—act in good faith to navigate their remaining contractual relationship.” Item 2: A new kind of couch co-op game A highlight of GDC each year is the Alt.Ctrl showcase that features games played with extremely experimental controllers. Perusing this year’s offerings last Friday, I found a game controlled with giant scissors, another with big toothbrushes and one that amounted to dumpster diving. My favorite was Pivot, a co-op game about collectively maneuvering a couch. It was developed by students at the University of Utah’s masters of arts and engineering games program. Players lift and tilt the physical couch in order to control the position of a virtual one. That virtual one is moving through an obstacle course on-screen, while being pursued by a giant skull. Developer Nishant Verma told me at GDC that the couch is made of styrofoam (this became more evident as I watched!) and that the name was a riff on an episode of the sitcom Friends. Item 3: In brief… 🚫 Ubisoft is laying off more than 100 workers at its Red Storm studio, as the North Carolina location known for decades for its Tom Clancy games, ceases in-house game development, VGC reports. 👀 On Monday, Nvidia’s revealed its DLSS 5 AI-driven graphics technology that purports to improve game graphics… and it has been roasted about it by the media and the online gaming public for the remainder of the week. The tech changed the faces of characters in footage from Resident Evil Requiem, Hogwarts Legacy and EA Sports FC, drawing accusations of giving carefully art-directed games the generic look of AI “slop.” Nvidia CEO Jensen Huang had said on Monday that “DLSS 5 is the GPT moment for graphics—blending handcrafted rendering with generative AI to deliver a dramatic leap in visual realism while preserving the control artists need for creative expression.” By mid-week, Huang was telling Tom’s Hardware that the new tech’s critics were “completely wrong” because game-makers could still “fine-tune the generative AI” to suit their game’s aesthetics.
Are You One of Those Weirdos Who Wants More Money in Politics? Move to West Virginia!
A shady new political donations law just passed, and so the age-old effort to keep the Mountain State an oligarch’s playground rolls onwards.
Arts and Entertainment Agenda: March 20-27
Consensual Improv, March 20 Roaring Fork Valley’s one-and-only improv comedy troupe is back. Consensual Improv will be hosting an upcoming show at 8 p.m. March 20 at The Arts Campus at Willits. Since 2016, they...
Implementing the Trump Administration’s America First Global Health Strategy in Angola - United States Department of State
Today, the United States and the Republic of Angola signed a five-year bilateral health cooperation Memorandum of Understanding (MOU), advancing the Trump Administration’s America First Global Health Strategy in Africa. Working with Congress, the Department of State intends to provide $71 million to support HIV, malaria, and global health security programming, while Angola will invest […]
Spring Position Battles: Cornerback
If there’s one constant across the Mizzou defense entering the 2026 season, it’s transition — and nowhere is that more apparent than at cornerback. Like nearly every other defensive position group, the Tigers lost a massive amount of production at corner this offseason. Both starters from last fall, Dreydon Norwood and Toriano Pride, Jr., have […]
Uber strikes deal with Rivian to buy thousands of robotaxis
The two companies announced a deal that will see Uber buy 10,000 fully autonomous Rivian robotaxis and invest up to $1.25 billion in the Tesla rival.
This Cleveland County restaurant closed after 20 years in business
Mountain View Restaurant in Kings Mountain has closed its doors after 20 years serving homestyle cooking to the community.
The Best Restaurants to Book in Copenhagen Right Now
The Danish capital shows off spots that make for destination dining, even as its most famous dining spot, Noma, comes under fire.
Beach parking, money in politics and more: Four San Diego measures move one step closer to November ballot
Support was unanimous for three of the measures, but the committee vote was only 3-2 in favor of a measure to ban paid parking at beaches and bays.
Snowmass considers defining new ‘business district’ for Draw Site, among other updates
Snowmass Town Council might consider a new business district after it was proposed Monday as a way to include small businesses in funding and priority housing for the Draw Site housing project.
Pre-litigation meeting fails to resolve dispute between businesses and Black Mountain
An update now on a story we’ve been following for you, the ongoing dispute between Black Mountain Brewing and the Town of Black Mountain.
Chris Weidner: Climbing past the politics: the Iran I remember
Our first impression of Tehran was overwhelming. From the hillside beneath the Alborz Mountains we looked upon a sea of mostly white buildings — a metropolis home to more than 8 million people. Down there, thick pollution stung my eyes and …
The World's Best Business Class Airline Lounges: My Top Picks Globally
What are the best business class lounges in the world? Here are my top picks, from Cathay Pacific in Hong Kong, to Delta in New York.
Scientists Discover the Brain Chemical That Helps Break Old Habits
A mouse study highlights the role of acetylcholine in behavioral flexibility, offering new insight into the brain mechanisms involved in addiction and obsessive compulsive disorder.
Snowflake Launches Project SnowWork, Bringing Outcome-Driven AI to Every Business User
MENLO PARK, Calif. – March 18, 2026 – Snowflake (NYSE: SNOW), the AI Data Cloud company, today announced the research preview of Project SnowWork, a new autonomous enterprise AI platform designed to help business users massively accelerate workflows.
Shohei Ohtani will return to the mound for Dodgers Wednesday
Roberts said the plan is for Ohtani to pitch in one more preseason game
Video: Business Report Hall of Fame honoree Bob Greer
A respected figure in the insurance and banking industries, Robert Stephenson “Bob” Greer Jr. made an indelible impact on Baton Rouge, combining an abiding love for his hometown with ambitious ideas on how to make it better. Greer was recently named a 2026 Hall of Fame laureate (posthumous) by Business Report. Watch the video of Bob […]
Oil prices hold steady even as Iraq resumes some exports via Turkey
Oil prices held steady Wednesday after Iraq clinched a deal to resume some crude exports via Turkey. It’s not a ton of oil, but it’s what amounts for good news these days as the Strait of Hormuz remains largely blocked.
Madison County considers rezoning along scenic byway near Marshall
Lonesome Mountain Market owner Johnny Moore purchased the building in 2022 with the purpose of operating a general/convenience store, he said.
Foxboro approves World Cup entertainment license - Boston News, Weather, Sports
FOXBORO, MASS. (WHDH) - Foxboro town leaders voted unanimously Tuesday to approve the entertainment license needed for the FIFA World Cup games to move forwardRead More
Foxborough Select Board unanimously approves entertainment license for FIFA World Cup
The Foxborough Select Board unanimously approved an entertainment license for the FIFA World Cup matches at Gillette Stadium.
Bill to tighten mental health diversion passes key Senate committee
Assembly Bill 46 took a big step toward becoming law on Tuesday. The bill, designed to address what many believe is a loophole in the state’s mental health diversion program, was unanimously approved by the Senate Public Safety Committee.
Spigen's New AirPods Pro 3 Case Is Modeled After the Original Macintosh Mouse
Accessory maker Spigen this week expanded its lineup of case options that are designed to look like vintage Apple Macs. The clever new Classic LS AirPods Pro 3 Case resembles a the iconic Apple Macintosh mouse, so it goes well with Spigen's Mac-style iPhone cases. Priced at $25 from Amazon, the case features the stone color that was used for the Classic Macintosh, along with a gray mouse button.
Project SnowWork: The easiest way for business users to get work done
Today, we are announcing Project SnowWork (Research Preview), a new autonomous AI platform for business leaders and knowledge workers across finance, sales, marketing, operations and more designed to move beyond simple answers.
40th Annual San Joaquin County Science Olympiad Division B/C Results
Teams from Wicklund Elementary and Mountain House High take first place at the 40th annual San Joaquin County Science Olympiad Division B/C Competition.
Starfield finally lands PS5 release date, along with new story DLC and Free Lanes update which - among other things - adds a Milliewhale pet
After plenty of rumours and rumblings, Bethesda has today announced that Starfield is coming to PlayStation 5.
Talking Tactics: Brighton Defeat Exposes Sunderland’s Mounting Injury Crisis
Sunderland suffered their third home defeat against Brighton despite an encouraging performance - let’s look at the data…
Autonomous businesses – from Waymo to mattress stores – are on the rise
Have you ever walked into a business with no employees? You may soon; autonomous businesses are becoming more popular.
Coal Ridge athletic director named best in state after landmark year of Titans prep sports
Ben Kirk did not dedicate his life to the art of sports for recognition or praise. He did it because he knows how much sports can shape a young kid, and how much impact a...
Merlin and Inflection Point Acquisition Corp. IV Announce Closing of Business Combination
Merlin's Cessna Caravan Merlin's aircraft flying overhead at the company's Quonset, RI hangar Merlin's Quonset, RI Hangar A C-130J flying overhead at Merlin’s Quonset, RI hangar Transaction provides more than $200M in gross proceeds to accelerate commercialization of AI-powered autonomous aviation Merlin to Begin Trading on March 17th on the NASDAQ Under Ticker Symbol “MRLN” BOSTON, March 16, 2026 (GLOBE NEWSWIRE) -- Merlin, Inc., an aerospace and defense technology company building the operatin
Cornyn clashes with progressive Rep Greg Casar in heated airport face-off over DHS shutdown
Texas Sen. John Cornyn and Rep. Greg Casar clashed over the DHS shutdown as TSA workers missed their first paycheck and airport delays continue to mount.
'Empty refrigerators and eviction notices': TSA union leaders demand end to DHS shutdown
TSA workers in Atlanta face a mounting financial crisis as the Department of Homeland Security shutdown continues, with agents dealing with evictions and hardships.
Aspen Valley Health partners with electronic health record platform
Aspen Valley Health has announced the launch of an Epic Connect partnership, aiming to shift how independent rural hospitals access advanced healthcare technology in alignment with local governance.
Sen. Schmitt accuses Democrats of playing ‘petty politics’ as DHS funding fight continues
Sen. Eric Schmitt, R-Mo., discusses the mounting national security concerns amid the DHS shutdown, responds to Democratic criticism of ICE and more on ‘America’s Newsroom.’
Men’s Health 2026 Grooming Awards: Shave Kit, Hair Serum, More
Men’s Health editorial director Richard Dorment joins TODAY to share some of the winners from the 2026 Grooming Awards. Products include hydrating pillow pads, mouthwash packets and more!
Haims: Jujube(s) have health benefits for sleep, Parkinson’s and Alzheimer’s
If you’re old enough to remember enjoying a box of Jujubes at the movie theater, you’re old enough to question this article’s title. If not, here’s the scoop. For decades, Jujubes candy was a movie theater staple. They look like very short rabbit pellets, similar in size and...
Grapefruit vs. Grapefruit Juice: Which is Better for Immunity and Fiber?
Whole grapefruit and grapefruit juice both have substantial amounts of vitamin C. However, whole fruit is a better way to get antioxidants and fiber that your body needs.
Alto Neuroscience Reports Full Year 2025 Financial Results and Recent Business Highlights
MOUNTAIN VIEW, Calif., March 16, 2026--Alto Neuroscience, Inc. ("Alto") (NYSE: ANRO), a clinical-stage biopharmaceutical company focused on the development of novel precision medicines for neuropsychiatric disorders, today reported financial results for the full year ended December 31, 2025, and highlighted recent progress across its pipeline of clinical-stage product candidates.
Scientists Reveal the Simplest Rule for Building Strength
New resistance-training guidelines show that any amount of strength training can significantly improve muscle, strength, and physical function.
Battle of the Badges Hockey Championship raises $285K for Dartmouth Health Children's
This year, the event raised $285,000, the largest single-day total in the event's 18-year history.
Dartmouth Health to open new addiction treatment center in Claremont
Dartmouth Health opens an outpatient addiction treatment center at Valley Regional Hospital in Claremont, providing convenient and timely care.
How Foreign-Trained Health Workers Saved the NHS £14 Billion
This blog is part of a series focused on the UK’s recruitment of foreign-trained health workers. This first blog details the amount of money the UK’s National Health Service (NHS) has saved by recruiting foreign-trained health workers. The second blog examines whether this saving is offset by foreign aid contributions to health systems strengthening (HSS) and human resources for health (HRH) in countries of origin.
Venomous Snakes Represent a Serious Public Health Problem. Scientists Are Biting Back With a Grou...
YVCF habitat fund awards 3 grants targeting invasive weeds, river health and post-fire recovery
The Wildlife Habitat Improvement Local District Endowment Fund has awarded three grants to support habitat projects across Routt County, backing work on invasive weeds, river health and post-fire forest recovery, according to a statement released...
Yampa Valley Regional Airport awarded $3 million grant for Aviation Business Park
Routt County has secured a $3 million federal grant to advance infrastructure work at the Yampa Valley Regional Airport’s Aviation Business Park, a project expected to boost economic growth and create jobs across Northwest Colorado, according...
Astros vs. Marlins 3/15/2026 Spring Training Game Thread
The Houston Astros (8-10-3) host the Miami Marlins (8-10-2) in Grapefruit League play. RHP Cristian Javier is set to make his second start of the Grapefruit League. RHP Eury Perez will be on the mound for the Marlins. TODAY’S STARTER: RHP Cristian Javier is making his second start of the Grapefruit League this season. In […]
Rumour: Pokemon Legends Galar to be prehistoric Pikmin-like game commanding groups of up to 30 Pokemon
The next Pokemon Legends game which is currently titled Pokemon Legends: Galar will seemingly have a Pikmin-like aspect where you can command up to thirty Pokemon in your squad. The game was leaked as…
Airline CEOs torch lawmakers for turning air travel into a ‘political football’
Airline leaders warned the DHS shutdown left TSA workers unpaid and travelers facing long lines as spring travel demand surged and pressure mounted on the aviation system.
Scientists revive activity in frozen mouse brains for the first time
A familiar trope in science fiction is the cryopreserved time traveller, their body deep-frozen in suspended animation, then thawed and reawakened in another decade or century with all of their mental...
Scientists revive activity in frozen mouse brains for the first time
‘Cryosleep’ remains the preserve of science fiction, but researchers are getting closer to restoring brain function after deep freezing
Flames Rally Falls Short in 3–2 Loss to Islanders
The Calgary Flames mounted a late push but couldn’t overcome a rough opening period, falling 3–2 to the New York Islanders on Saturday night in Long Island.
Summit High School science teacher wins award
The National Association of Geoscience Teachers announced in a recent news release that Summit High School teacher Mary Slack has been awarded the Outstanding Earth Science Teacher Award for the Rocky Mountain section. This award...
Intermountain Health employee pleads guilty after stealing 100+ prescriptions from Colorado patients
A former employee of Intermountain Health in Colorado has pleaded guilty after she stole more than 100 prescriptions from patients being treated for significant pain.
Evidence mounts suggesting health costs from WV lawmaker moves on data centers, water
In a span of less than half an hour March 12, 2026, the West Virginia House of Delegates made three moves undermining the state’s already poor drinking water quality. Moves the House of Delegates and Senate have made in the 2026 legislative session's final days are likely to inflict significant health costs, recent studies suggest.
Opposition Lowdown: Tom Cleverley’s Plymouth Argyle
Reading return home to the SCL Stadium this weekend when they take on Plymouth Argyle. Join us as we take a closer look at the opposition.
High school students to compete in UMass Dartmouth business challenge
Over 200 high school students will compete in a business challenge at UMass Dartmouth to learn real-world skills.
High school students to compete in UMass Dartmouth business challenge
Over 200 high school students will compete in a business challenge at UMass Dartmouth to learn real-world skills.
The 'Science' of Global Warming Theory Just Suffered Another Big Hit
Do you fear the theory of “global warming”? If so, how deep is your fear? As in would you be willing to bet a substantial amount of your net worth that the theory is not just real, but ear
Scientists discover ancient DNA “switches” hidden in plants for 400 million years
Scientists have uncovered an enormous hidden archive of plant DNA that has endured for more than 400 million years. By comparing hundreds of plant genomes, researchers identified more than 2.3 million regulatory DNA sequences that act like genetic switches, controlling when and how genes are activated. These sequences, known as conserved non-coding sequences (CNSs), were detected using a new computational tool called Conservatory.
Forging Health Partnerships Under the Trump Administration’s America First Global Health Strategy in Honduras and Senegal - United States Department of State
The United States signed bilateral health cooperation Memoranda of Understanding (MOUs) with the Republic of Honduras and the Republic of Senegal, marking significant milestones in advancing the Trump Administration’s America First Global Health Strategy while strengthening our partnerships in the Western Hemisphere and Africa. In Honduras, the Department of State signed a five-year, $46.5 million […]
WATCH: Vance speaks in new North Carolina district seen as competitive for GOP in 2026
Vice President JD Vance delivered remarks on the economy Friday in Rocky Mount, North Carolina, in a newly redrawn congressional district seen as competitive for the Republican Party in the November midterms.
Judge quashes Justice Department subpoena of Federal Reserve
Judge James Boasberg said that a "mountain of evidence suggests" that the purpose of the subpoenas was simply to pressure the Fed to cut its key interest rate
Passenger’s mental health episode turns ferry around - The Martha's Vineyard Times
A Vineyard Haven man’s mental health episode forced a Steamship Authority ferry to turn around and head back to Woods Hole shortly after departing this week. On Tuesday morning, Falmouth Police responded to the ferry terminal in Woods Hole for what was described as a “disruptive passenger” aboard the passenger ferry M/V Woods Hole shortly […]
Roush Review: In Woeful ‘Madison,’ Michelle Pfeiffer Gives Emmy-Worthy Performance
Michelle Pfeiffer stars as an elegant city mouse who ventures into a gorgeous Montana river valley to heal after a tragedy in Taylor Sheridan's cathartic and elegiac drama.
Teen Mental Health Survey Is Open
Youth between 12 and 19 years old are encouraged to complete the anonymous survey through April 30.
Five Iron Golf Indoor Entertainment Venue Coming to Forth Worth's Near Southside
Five Iron Golf’s Fort Worth location will be its first in Texas. Projected to add 40 jobs to the local economy, it will feature 12 Trackman simulators with multi-angle swing-capture technology and access to more than 300 famous courses around the world. The venue will feature a full-service bar and kitchen, along with flexible indoor event spaces including a private bay.
Colorado committee recommends rejecting alcohol, marijuana tax hike to fund mental health care
In a rare move, Colorado’s Capital Development Committee unanimously recommended that another legislative committee reject a bill asking voters to approve higher excise taxes on alcohol and marijuana to fund a new mental health hospital in Aurora. Sponsored by Rep. Bob Marshall, D-Highlands Ranch, and Sen. Judy Amabile, D-Boulder, House Bill 1301 proposes that all […]