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Maryland’s new hospital payment model could drive up health insurance costs
Insurers warn the transition could shift more expenses to private payers and consumers while testing the stability of the state’s unique health care system.
Solina acquires Epicurean Butter
Epicurean Butter has been partnered with HC Private Investments since 2019.
Unearthed El-Sayed essay draws explosive Trump-bin Laden parallel: ‘recruited, radicalized and reassured’
Abdul El-Sayed's now-private 2021 blog post argued Trump should be treated like Osama bin Laden, calling the Capitol riot comparable to 9/11.
Business innovation requires better boundaries
Three ways leaders can lead with risk capacity.
I Wore an Electrical Muscle Stimulation Body Suit to Zap Myself Into Fitness
Can electrifying your workout offer a shortcut to a stronger, fitter you? I sweated in a skintight EMS suit for two months to find out.
Create, connect, and cultivate with hundreds of businesses at the 2026 Triad Business Expo
Whether you're an aspiring entrepreneur, an established business owner, or a professional looking to elevate your success, the 2026 Triad Business Expo has something for you.
$5 billion science research bond clears California Assembly committee
The California Assembly Appropriations Committee voted Thursday to advance a UC-sponsored bond measure that would fund scientific research across the state. The California Science and Health Research Bond Act – or Senate Bill 895 – would create the California Foundation for Science and Health Research to award $5 billion in grants and loans to public and private research institutions, including UC campuses.
“Taking the Twinkle Out of Stars” presented by Kona Science Cafe at Hawaiʻi Keiki Museum
Join Staff Astronomer Preethi Krishnamoorthy and Adaptive Optics Scientist Avinash Surendran as they explain how Keck Observatory takes the twinkle out of stars at the Hawaiʻi Keiki Museum’s upcoming Kona […]
MSSU opens new health science building
A new $48 million building officially opens at Missouri Southern.
Trump Gives Green Light to U.S. Companies to Aim Hacks at Cybercriminals
The practice would align the United States more closely with countries like China and Russia, where spy agencies have long relied on private-sector hackers to help with national security missions.
AP report: Kennedy Center board moves forward with a two-year closure to allow for renovations
The Kennedy Center will move forward with a two-year closure of the sprawling performing arts venue to allow for substantial renovation work, while some outdoor programming may continue.
Trump’s handpicked Kennedy Center board votes a second time to close performing arts center for renovations
President Donald Trump’s handpicked John F. Kennedy Center board has voted a second time to close the performing arts institution for renovations, according to a person who was briefed on the decision.
Jennifer Garner cofounded a $732 million business at 45, and says her age came with perks: ‘I’m blissfully not motivated by needing to be in charge’
Millionaire actress Jennifer Garner became a cofounder after two decades in Hollywood success, and says she had one big advantage over younger founders.
Kingdom Come Salvation Targets 2028: The Engine Upgrades We Need to See
A rapid return to Bohemia.
‘Cause we (still) rock! The Jonas Brothers introduce a new generation in nostalgia-filled Camp Rock 3
Get behind-the-scenes details of ‘Camp Rock 3’ with Joe, Kevin, and Nick Jonas — including what it was like to reunite with Demi Lovato — and meet the new cast of stars in EW’s exclusive cover story.
Girls flag football elevated to 29th varsity sport in Ohio
The Browns were the driving force and led efforts in the elevation process, with the sport exploding in popularity
AI needs science’s search history
“Actually, that’s where the gold is,” said Alasdair Russell, my graduate school friend who leads a pre-clinical genome editing group at Cambridge. He was talking about the winding road of science that is omitted from published papers. “When you’re discussing how to do the experiment, and why this way is better than another way, and what does the data really mean? I know what it shows, but what does it mean?” At RAAIS 2026, he described how his group has begun logging the twisting path of discovery as it happens, recording the verbal and written exchanges that normally disappear. Ideas become nodes in a living graph: they branch when a meeting produces two plausible experiments, merge when separate lines of evidence converge, and go dark when someone quietly stops pursuing them. In his implementation, one agent scores novelty, while another tries to learn “how scientists think and how they navigate through a complex world of data,” so that high-potential nodes can trigger deeper investigation. As frontier AI labs deploy agents toward scientific discovery, giving AI authentic scientific taste remains a trillion-dollar dilemma. The bottleneck is that the record we have kept for centuries of science might be insufficient to get us there. The experiments that never make the paper Peter Medawar, 1960 Nobel laureate and “father of transplantation,” asked in 1963 whether the scientific paper was a fraud, and answered yes: the form of the paper misrepresents the thinking that produced it. Sixty years on, the diagnosis is unchanged. A paper presents a clean progression from hypothesis to result to conclusion. Lost along the way are the unconventional theories, the abandoned or unaffordable methods, and the underwhelming and inconclusive data. It reads like a browser history with every dead end deleted: the ten open tabs, the four rephrased queries, the wrong turn down a subforum. All scrubbed, leaving one clean path from question to answer as the canonical path. What has changed since then is that the discarded material is now worth something. No high-impact journal wants these artifacts, but raw trial and error is the most likely source of the training data required to develop scientific intuition, or what researchers call taste. Earlier attempts to capture the discards were motivated by scientific integrity. The Journal of Negative Results in Biomedicine launched in 2002 to publish rigorous studies that disputed established models or exposed ineffective treatments. Its archive preserved negative conclusions after they had become papers, rather than the live alternatives and arguments that produced them. BioMed Central closed it in 2017, saying the mission had been served now that other journals publish null results. A less generous reading is that in fifteen years it published around 200 papers because almost nobody wants to read a negative result, let alone write one up when it will not count toward academic tenure. AI models are different. Even an uninteresting negative result can be useful, provided it is labeled. Earlier this year, Anthropic put a version of this to the test. The company pulled 129 decision points from real Claude Code sessions between January and March 2026, showed models the work up to a human detour, and asked what should happen next. Claude Mythos Preview beat the human choice 64% of the time, while Opus 4.5 managed 51%. The comparison was tilted toward the models because Anthropic deliberately chose moments where the human decision had room for improvement. On 127 further scenarios where the human action was already strong, the models improved on it only about 20% of the time. The study was possible because Anthropic’s researchers work inside a tool that logs by default. The reasoning, detours and outcome are produced in the same working environment. Biology has no equivalent. Its reasoning happens in hallways, at benches, in Slack threads and on whiteboards, while the outcome arrives weeks later somewhere else. The record has to emerge from the work itself. Ask scientists to reconstruct it afterwards and we’ll create another polished account. Subscribe A log is not a label Before any of this becomes training data, a negative result has to say what failed. The first paper published in the Journal of Negative Results in Biomedicine examined 234 negative studies across five leading medical journals. Only 30% discussed statistical power, and half clearly defined a primary outcome. Tell a model an experiment failed, without telling it whether the assay was underpowered, a reagent had degraded, or the hypothesis was simply wrong, and it will learn noise with confidence. Decision histories have a second missing label too. When a lab considers five experiments and runs one, only the chosen branch returns an outcome. The other four are experimental counterfactuals. Researchers call this the selective labels problem: the data reveal results only for the actions someone chose to take. Such a record can teach a model to imitate a lab’s taste, but it cannot establish that the taste was good. It also smuggles local constraints into general lessons. A lab that never ran cryo-EM because it did not own a microscope teaches a model that cryo-EM is rarely the right call. Alasdair’s nodes preserve the candidate set, which is the necessary first step. To be useful, each decision record needs six fields: The evidence available at that moment, and nothing that arrived later. The candidates considered, including the ones dismissed in a sentence. For each candidate: the expected result, the confidence attached to it, and the cost in time and money. The route chosen, and the reason. What happened next. How the evidence changed the scientist’s view. These must be timestamped before the outcome, because hindsight turns uncertainty into inevitability. Disagreement also has to survive. Averaging three scientists into one clean rationale reproduces exactly the information loss we are trying to fix. But there is an obvious failure mode here. Once decisions are logged and scored, people log for the record post-facto. Anyone who has watched an electronic lab notebook fill up with retrospective tidying knows how quickly a research tool becomes a compliance exercise. A record that costs a scientist ten minutes of honest reflection per decision is worth far more than one that costs an hour of performance. A publication initiative called Registered Reports offers a useful starting point. Here, researchers submit their rationale, methods and analysis plan for peer review before the data exist, and the journal commits in principle to publish if they follow the approved plan. Nature has now expanded the format across every field it covers. This approach to paper writing timestamps intent before the outcome, but it freezes one plan. A useful search history must also preserve how the plan changed, which alternatives were rejected, when, and on what evidence. Subscribe Run the runner-up Autonomous labs show what happens when decisions and outcomes are connected in a loop. Liverpool’s mobile robotic chemist ran 688 experiments over eight days in a ten-variable formulation space. A batched Bayesian search used each result to choose the next experiments and found photocatalyst mixtures six times more active than the starting formulations. Every completed experiment changed what the system did next. The robot optimized within a goal and search space that humans had already chosen. It did not decide which scientific question mattered. So what this work demonstrates is narrower, but still useful: a search history pays off when the options return standardized outcomes quickly. Open-ended biology is harder because branches can take weeks and the discarded alternatives may never be run. Some exploration therefore has to be bought. Where two branches are plausible and the stakes justify the cost, a lab should sometimes run the runner-up. Otherwise the record captures what today’s scientists usually chose and stays silent on what they systematically overlooked. A funder could ring-fence a small fraction of a grant for the branch not taken, provided that the decision record and the outcome are both deposited. That costs money, but so does having every lab rediscover the same abandoned path. Test whether taste transfers When it comes time to evaluate if our new AI system exhibits taste, the comparison should run across laboratories and fields. At selected decision points in a live research campaign, we should freeze the six fields: the evidence, the candidates, expected results, confidence, costs and the choice made. Experts then rank the options before the outcomes are known, and those outcomes are checked independently later. We could give models one of two diets - papers alone, or papers plus decision histories - and ask them to rank the next experiment on unfamiliar projects. Then, we score information gained per dollar and week, calibration, and how quickly weak branches are abandoned. If histories improve choices only inside the lab that produced them, they amount to useful organizational memory. If they improve choices on unfamiliar problems elsewhere, Alasdair’s group will have captured something science has never managed to write down: a transferable record of taste. Until that happens, a scientific search history is a promising record, not yet a training set.
Turkiye’s AK Party turns 25: A journey of change and renewal
In a quarter-century, the party has strengthened democracy, driven development and elevated Turkiye’s global standing.
Philadelphia Union Unveil Retro-Inspired “Philly Kit,” a Tribute to Philadelphia Sports
The club’s official third kit pays homage to Philadelphia’s unmatched sports culture
New review prioritizes maternal mental health during pregnancy
(2 min. read)
When Apollo came to the Bronx
Private equity’s entrance into baseball is a sign of the times
Computer and environmental science take flight with bird conservation collaboration
Susquehanna University’s computer science department is getting involved with bird conservation through a data management collaboration with the Middle Susquehanna Riverkeeper Association.
Scientists uncover new clue to how protons maintain their identity
New results from the STAR detector at the Relativistic Heavy Ion Collider (RHIC) suggest that gluons, the gluelike particles that hold quarks together inside protons, play a central role in the conservation of baryon number, an essential part of a particle’s quantum identity.
Scientists develop innovative hybrid material for hydrogen peroxide production
Recently published research from a team led by scientists at Argonne National Laboratory demonstrates how a hybrid of biological components and technology can be used to efficiently produce hydrogen peroxide and other chemicals.
The Swift Rescue Mission Could Be Back in Business
After a nearly catastrophic failure, a software update renews hope of saving NASA's Swift observatory before it burns up.
UVA Health elevates Dr. Nassima Ait-Daoud Tiouririne from interim to permanent Dept. of Psychiatry chair
The UVA Health career provider has led the effort to serve unhoused at The Haven.
Five Takeaways: North Idaho Economic Activity
For its latest episode of Elevating The Conversation, the Journal sat down with Wally Jacobson, executive director of the Panhandle Area Council and the interim executive director of the Coeur d’Alene Economic Development Corp., to discuss North Idaho economic activity.
Former SPLC official charged in Justice Department's broader criminal case against group
A former Southern Poverty Law Center official has been charged in the Department of Justice’s broader criminal case against the Alabama-based civil rights group, a frequent target of conservative critics who claim the nonprofit is politically biased.
Asia-Pacific parliamentarians urge bolder action for universal health coverage, climate resilience and responsible AI
Parliamentarians representing 16 countries from across the Asia-Pacific region concluded the Ninth Meeting of the Asia-Pacific Parliamentarian Forum on Global Health (APPFGH) today, reaffirming their key role in advancing universal health coverage (UHC) amid the risks and opportunities posed by AI and climate change. In adopting the Phnom Penh Communiqué, parliamentarians urged fellow legislators regionwide to strengthen sustainable financing for UHC to widen access to health for all, including the most vulnerable populations; promote responsible governance of AI amid ethical concerns over this fast-evolving technology; and build climate-resilient health systems to anticipate and respond to mounting pressures ranging from rising sea levels in coastal areas to air pollution and other environmental degradation.The National Assembly of Cambodia, with support from Cambodia’s Ministry of Health and the World Health Organization (WHO), hosted the Forum in Phnom Penh from 11 to 13 August 2026 – the first time the Forum has convened in a Mekong country.Parliamentarians urge action to close gaps in accessIn the Communiqué, parliamentarians recognized that at-risk and marginalized groups are the ones most severely affected by gaps in access to health services. These groups include people living in poverty, women and children, persons with disabilities, older people, migrants, refugees, and those in rural, remote or island communities. The Communiqué urges fellow parliamentarians and policy-makers to advocate for laws and policies that support sustainable financing to protect people from financial hardship, with a focus on primary health care, prevention and equity. "The Communiqué is a call to action. It sets out ambitious, concrete measures that deliver meaningful impact on the ground. We are all accountable for advancing universal health coverage and translating our commitments into tangible results. Cambodia is fully committed to advancing UHC, including the promotion of ‘healthy people, prosperous country’ campaign,” said Samdech Maha Rathsapheathika Thipadei Khuon Sudary, President of the National Assembly of the Kingdom of Cambodia.His Excellency Professor Chheang Ra, Minister of Health of the Kingdom of Cambodia, highlighted the need for collaboration beyond the health sector. “Universal health coverage cannot be achieved by the Ministry of Health alone. It requires support, particularly from parliamentarians, across political, legislative, financial, social protection, education, infrastructure, and environmental domains. While each country follows its own path, one factor is universally critical for success: strong governance and leadership. We all believe in this principle, and in our respective political roles, we remain committed to strengthening these key success factors to ensure that no one is left behind.”Promoting responsible AI adoption Parliamentarians acknowledged that, while AI has already demonstrated its ability to improve access to health services and support delivery, careful and ethical governance is necessary to safeguard quality, safety, privacy and public trust. This underscores the importance of parliamentarians in promoting legal and regulatory frameworks addressing liability, records ownership and data governance, while embracing innovation that protects ethical practice.“Without strong governance, safeguards for privacy and data security, sustainable financing, and attention to those most at risk of exclusion, new technologies may widen existing gaps instead of closing them. This is why parliamentarians matter. We pass laws. We approve budgets. We scrutinize government action. We represent communities. We can ask whether health services are reaching rural, remote, ageing, poor, and marginalized populations. We can ask whether innovation is being guided by equity, evidence, and ethics,” said Hon. Man Hee Lee, President of the Asia-Pacific Parliamentarian Forum on Global Health.Building climate-resilient health systemsParliamentarians also reiterated that the climate crisis is a direct threat to people’s health and to achieving UHC more broadly, deepening the same gaps in access already faced by at-risk and marginalized communities. They recognized the need for WHO Member States to ensure sufficient national appropriations and oversight, and for parliamentarians to raise awareness in their constituencies and mobilize local action in building climate-resilient and sustainable health systems.“Universal health coverage, climate change and AI cannot be addressed in isolation. The same communities struggling to access health services today are often the ones most exposed to climate shocks, and most in need of the opportunities AI can offer if this technology is governed responsibly,” said Dr Saia Ma’u Piukala, WHO Regional Director for the Western Pacific. “Having served previously in this Forum myself as a parliamentarian from Tonga, I recognize how the Phnom Penh Communiqué reflects the shared resolve of legislators across the Asia-Pacific region: the laws parliamentarians pass and the budgets they approve help ensure this progress reaches the people who need it most.”As the Forum drew to a close, delegates reflected on what they would carry back to their own parliaments and constituencies.“I wish to share three points here worth carrying home from Phnom Penh: we need to invest in primary health care as the foundation of coverage; we need to remove the barriers that keep people from care, whether financial, geographic or social; and we need to build systems that are inclusive by design, protecting those most at risk of being left behind,” added Hon. Ouch Borith, First Vice-President of the Senate of the Kingdom of Cambodia.###Notes for editors:The Asia-Pacific Parliamentarian Forum on Global Health (APPFGH) is a platform for parliamentarians to exchange ideas, build political will, strengthen capacity and foster collaboration towards sustainable health action. This was the ninth meeting of the APPFGH, with the theme “Universal Health Coverage in the era of Climate Change and Artificial Intelligence”. Target 3.8 of the Sustainable Development Goals calls on countries to achieve universal health coverage, including financial risk protection, access to quality essential health services, and access to safe, effective, quality and affordable essential medicines and vaccines for all. In the Western Pacific, UHC service coverage index (SDG 3.8.1) rose from 63 in 2000 to 81 in 2023 (figures include Indonesia), and roughly one in four people in the Western Pacific have experienced financial hardship (SDG 3.8.2). Progress towards UHC in the Asia-Pacific region remains uneven, with hundreds of millions of people still lacking access to essential health services or facing financial hardship due to health-related expenses. Strengthening the role of parliaments – through legislation, financing and oversight – is central to closing this gap and accelerating progress towards UHC across the region.Parliamentarians participating in APPFGH in Cambodia this week include: Hon. Pehin Dato Adanan YUSOF, Brunei Darussalam; Hon. Rosmawatty ABDUL MUMIN, Brunei Darussalam; Hon. LORK Kheng, Kingdom of Cambodia; Hon. YOS Phanita, Kingdom of Cambodia; Hon. KHOUN Khundy, Kingdom of Cambodia; Hon. HENG Halim, Kingdom of Cambodia; Hon. KHOENG Noupheap, Kingdom of Cambodia; Hon. SENG Nhak, Kingdom of Cambodia; Hon. LY Sukry, Kingdom of Cambodia; Hon. NHOEURN Raden, Kingdom of Cambodia; Hon. Dr Ratu Atonio LALABALAVU, Republic of Fiji; Hon. Vijay NATH, Republic of Fiji; Hon. Man Hee LEE, Republic of Korea; Hon. Dr Jiho CHA, Republic of Korea; Hon. Jonghun BAEK, Republic of Korea; Hon. Youngsuk SEO, Republic of Korea; Hon. Dr Phayvanh KEOPASEUTH, Lao People’s Democratic Republic; Hon. Suhaizan Bin KAIAT, Malaysia; Hon. Dr Perpetua KONMAN, Federated States of Micronesia; Hon. Ganmaa DAVAASAMBUU, Mongolia; Hon. Charmaine SCOTTY, Republic of Naoero; Hon. Vincent Ambance KUMURA, Papua New Guinea; Hon. Dr Edwin CRUZADO, Republic of the Philippines; Hon. AUUAPAAU Mulipola Aloitafua Mulipola, Samoa; Hon. ASIATA TAVUI Tafu Salevao, Samoa; Hon. Dr Alani Petelo TANGITAU, Tonga; Hon. Paul PAOLO, Republic of Vanuatu; Hon. Franklyn Ezra WILLIAM, Republic of Vanuatu.For more information, contact: WHO Regional Office for the Western Pacific: wprocom@who.int National Assembly of the Kingdom of Cambodia (International Relations Department): ir.nacambodia@gmail.com
Why Japanese firms are being so slow to use AI
Japanese risk aversion and conservatism blamed for slow AI take-up by the country's business sector.
South Carolina Senate Runoff Kicks Off With Chick-fil-A and Trump Calls
Darline Graham and Ralph Norman emerged from a special election sprint on Tuesday to succeed Lindsey Graham. She will sell her closeness to President Trump. He will tout his conservatism.
Azitra, Inc. Announces Q2 2026 Results and Provides Business Updates
/PRNewswire/ -- Azitra, Inc. ("Azitra" or the "Company") (NYSE American: AZTR), a clinical stage biopharmaceutical company focused on developing innovative...
Claim that science is becoming less disruptive challenged after years-long publication delay
A widely cited Nature cover article from 2023 claimed that scientific innovation has significantly declined in recent decades. This finding was based on a citation analysis of large sets of metadata concerning ...
Lazarus Exploits Windows Zero-Day to Gain SYSTEM Access and Deploy Backdoor
Lazarus-linked attacks exploit Windows CVE-2026-68820 as a zero-day to gain SYSTEM access and deploy Troy against defense and aerospace firms.
Bay Area science centers to host eclipse, meteor shower events
Bay Area science institutions will host events for people interested in today's total solar eclipse and the Perseid meteor shower.
Village Capital launches NWA investment facility
Washington, D.C.-based venture capital firm Village Capital recently launched a first-of-its-kind flexible investment facility supporting Northwest Arkansas-based startups. The Walton Family Foundation provided $700,000 to support the VilCap Innovative Capital...
Village Capital launches NWA investment facility
Washington, D.C.-based venture capital firm Village Capital recently launched a first-of-its-kind flexible investment facility supporting Northwest Arkansas-based startups. The Walton Family Foundation provided $700,000 to support the VilCap Innovative Capital...
Quality Assessment Report Evaluates Polar Geospatial Center EarthDEM Elevation Products
CSDA's assessment reports help inform the user community about the quality of commercial Digital Elevation Models (DEMs).
CSEC, Corus Entertainment Announce Five Year Radio Broadcast Partnership
Exclusive five-year partnership announcement for all Flames radio broadcasts across the region
New fellowships link research, communities, youth purpose
The Purpose Science and Innovation Exchange has received a three-year, $3.5 million grant from the Bezos Family Foundation to launch two new fellowships aimed to help youth develop a sense of purpose.
Rick Jackson unveils plan to revitalize Sweet Auburn, other historic Georgia business districts
GOP gubernatorial nominee pledges small business support, historic preservation in Sweet Auburn and five other historic neighborhoods across the state.
Rick Jackson unveils plan to revitalize Sweet Auburn, other historic Georgia business districts
GOP gubernatorial nominee pledges small business support, historic preservation in Sweet Auburn and five other historic neighborhoods across the state.
Inflation cooled in July but remained elevated as Fed weighs rate hikes
The Labor Department released the consumer price index (CPI) for July which showed that inflation cooled, even as the pace of price growth remained elevated.
Montenegro’s Minister of Education, Science and Innovation signs third agreement to partner with Oracle Academy to advance technology education
Montenegro’s Minister of Education, Science and Innovation signs third agreement to partner with Oracle Academy to advance technology education
Tennessee to execute Anthony Hines as attorneys raise concerns over health, execution team
Fox 17 provides local news, weather, sports, traffic and entertainment for Nashville and nearby towns and communities in Middle Tennessee, including Forest Hills, Brentwood, Franklin, Fairview, Dickson, Clarksville, White House, Greenbrier, Springfield, Gallatin, Hartsville, Lebanon, Mt Juliet, Smyrna, College Grove, Thompson’s Station, Centerville, Murfreesboro, Columbia, Lewisburg, Shelbyville, Manchester, McMinnville, Smithville, Sparta, Cookeville, Hohenwald, Waverly, Camden, Paris, Lafayette, Portland, and in Kentucky, Russelville, Bowling Green, Franklin, Alvaton, Scottsville, Hopkinsville, Glasgow.
Kylie Jenner and Timothee Chalamet Are ‘Vehemently Opposed’ to Kris Jenner’s ‘Televised’ Wedding Plans
Kylie Jenner and Timothée Chalamet are ready to follow in the footsteps of friends Tom Holland and Zendaya by tying the knot privately, a source tells In Touch. “They love that Zendaya and Tom were ab...
How we picked 35 of the world’s top young scientists and engineers
Our 2026 Innovators Under 35 list will be out soon. Here’s what we looked for as we sifted through 550 nominations from around the world.
AMGEN TO OPEN NEW SCIENCE & INNOVATION CENTER IN GENOME VALLEY, HYDERABAD
/PRNewswire/ -- Amgen (NASDAQ: AMGN) today announced plans to open a new Science and Innovation Center at Genome Valley in Hyderabad. The center will join...
Investing in young people is a win for business and society
Developing young people in the workplace is an imperative – and the private sector has the scale, expertise and market insight to help them acquire the needed skills and experience.
Myles Garrett missing practice with leg injury again
Offensive and defensive observations from Rams-Cowboys joint practice
NHL Tonight: Unfinished Business
NHL Tonight: The crew talks Unfinished Business and the latest news on the Dylan Larkin trade situation
NASA Swift Boost Spacecraft Prepares to Continue Mission
Katalyst Space uploaded a flight software update that reestablished attitude control of its LINK spacecraft, which is set to boost NASA’s Swift observatory.
St. Anthony Hospital names new chairman amid relocation effort
Dr. Peter McCauley, currently a strategic adviser for healthcare private equity firm 2Flo Ventures, will replace the hospital's former CEO Guy Medaglia.
Small business optimism rebounds in July, led by stronger hiring plans
NFIB said small business optimism rose above its long-term average in July, driven by stronger hiring and investment plans, though uncertainty remained elevated.
Eagles training camp observations: Elijah Moore making roster push
Here are our notes from Day 10 of Eagles training camp in 2026.
Curtain Call Cabaret & Lounge launches new pay model for entertainment, food
The Curtain Call Cabaret & Lounge in downtown Medford has introduced an innovative Pay-What-You-Want model that includes both admission and its food menu. For all Curtain Call-produced performances, guests may […]
Nashville's Main Street Health ranked fastest-growing private company in U.S.
Main Street Health is ranked fastest-growing company in U.S. thanks to creative approach to rural health.
Lucas Museum announces new restaurant inspired by Skywalker Ranch
The Lucas Museum of Narrative Art on Tuesday announced its flagship restaurant, Skywalker Grill. Nestled at the top of the museum with sweeping city views, the classic American eatery is now taking reservations.
Quantum trade moves beyond science fiction: AlphaCheck
Two newly public quantum computing companies are about to report earnings. Their results will test the appetite for the budding technology that has captivated some corners on Wall Street.
Today’s clicks can reveal tomorrow’s breakthroughs
The trail of likes, shares and downloads we leave across the internet could help predict successful innovations years in advance.
Blending Fusion Science, AI to Predict DIII-D Tokamak Behavior
Data scientists from the U.S. Department of Energy’s Thomas Jefferson National Accelerator Facility and partner institutions have developed a deployable machine learning (ML) framework that can adaptively predict changes in a magnetic confinement fusion research machine’s hardware. The innovative method, recently published in the journal Machine Learning with Applications, promises to help make the operation of fusion devices more stable and accelerate humanity’s pursuit of a superabundant
Yankees receive $2.6 billion in deal with private equity fund
The Yankees may use the money to handle debt and pursue new ventures.
America Already Built the World's Largest Science-Vetting Machine | The Foundation for American Innovation
Every year, federal agencies assess over a hundred thousand proposals that they never fund. Treating those peer review as public infrastructure could help unlock much more philanthropic capital for American research.
The U.S. Healthcare System is Already Mostly Socialized
Now that Abdul El-Sayed is the Democratic nominee for Michigan’s open Senate seat, the outcome of this crucial race will depend mainly on two things: Whether Republicans succeed in demonizing El-Sayed because he’s brown and a Muslim, and whether they succeed in demonizing him as a left-wing radical. I will defer for the now the question of whether bigotry will be effective this year, although I will address it another day. What I want to address instead is El-Sayed’s signature issue — healthcare. Yes, El-Sayed advocates Medicare for All, a position the usual suspects denounce as “socialism.” I will get to the politics of his stance soon. Today, however, I want to talk about the substance. We should be clear that El-Sayed doesn’t even call himself a socialist. On the contrary, he explicitly disavows the label, saying “I’m a capitalist who just knows about capitalism”. In fact, as I explained in a previous post, the policies that El-Sayed advocates qualify him as a social democrat, not a socialist. Still, El-Sayed advocates a system under which the government would pay almost all medical expenses. Isn’t that socialism? Well, if that is the criterion then much of U.S. healthcare is already socialist. In fact, the government’s role is so large that U.S. healthcare is better described as partially privatized socialism than as anything resembling a free market. Let’s start with the raw numbers on health insurance, which pays the bulk of Americans’ medical expenses. Americans receive health insurance either from private companies or from public programs, overwhelmingly Medicare and Medicaid. Here’s what the breakdown of coverage and spending between private and public looked like in 2024: While a majority of Americans with health insurance get it from private companies, well over 100 million of us are covered by government programs instead. And these government programs pay more total dollars for medical bills than the private insurers do. Why do government programs that cover a minority of the population account for a majority of health insurers’ outlays? Mainly because Medicare covers seniors, and we’re expensive. Also, while Medicaid covers many younger Americans, disabled and elderly beneficiaries account for most of its spending. Even by the raw numbers, then, U.S. health insurance looks as much public as private. But that understates the government’s role: Private health insurance in the U.S. is both highly regulated and heavily subsidized. This is obviously true for the insurance coverage purchased by tens of millions of Americans through the exchanges established by the Affordable Care Act. But employment-based health insurance, which covers 161 million Americans, is far more of a government creation than most people realize. For employment-based insurance exists largely because of huge implicit government subsidies that come with major strings attached. Here’s how that works. If your employer pays you $10,000, that’s taxable income. But if your employer pays $10,000 toward a company health insurance plan that meets certain criteria, it isn’t taxable. That’s a huge effective subsidy, running at more than $300 billion a year. Take that subsidy into account, along with the more than $100 billion per year spent subsidizing policies purchased under the ACA, as well as the outlays on Medicare and Medicaid, and net effect is that the government pays for more than two-thirds of Americans’ health insurance. Granted, there are strings attached. Roughly speaking, employment-based health plans can’t discriminate based on medical history — that is, they can’t deny coverage to employees with pre-existing conditions — and they also can’t offer the plans only to highly compensated employees — a health plan that is only for the C-suite is considered taxable income. So given the restrictions of the federal tax code, employer-based health insurance is a lot like Obamacare, which also prohibits discrimination based on medical history and provides subsidies to make insurance affordable to lower-paid workers. The fact is that virtually all of private healthcare insurance is already well under some form of government control through regulation and tax subsidies. How should we think about this system? First of all, is Medicare socialist? Don’t tell anyone, but the way Medicare operates — it covers every senior’s medical expenses, whatever they turn out to be, while being funded by taxes that depend on one’s income — could be summarized by the old Marxist slogan “From each according to his ability, to each according to his need.” And back in 1961, when Ronald Reagan was the face of a last-ditch effort by the American Medical Association to block the creation of Medicare, he denounced Medicare as “socialized medicine” and warned that it would destroy our freedom. In reality, American freedom survived until Jan. 20, 2025, while Medicare is immensely popular, with an 82 percent favorable rating in the most recent KFF survey. Medicaid, government health insurance for lower-income Americans, comes in at 73 percent. This is in sharp contrast to public views about private insurers, who are widely disliked if not hated and accused of denying essential care. Furthermore, if Medicare is socialism, then the whole U.S. health insurance system, with the government paying most of the bills and placing conditions on private insurers, is almost equally socialist. If you insist on calling any program the government pays for and regulates socialist, then U.S. healthcare would best be described as a partially privatized form of socialism. And one must ask, what is the point of the part that is privatized? Do private insurers add anything positive? Or are they simply parasites, skimming off money that could have been paying for care? The case for viewing insurers as parasites is strong. Many Medicare benefits are now delivered via Medicare Advantage, that is, plans paid for by the government but run through insurance companies. MedPAC, an independent advisory commission, estimates that last year Medicare Advantage plans were overpaid by $84 billion, thanks to practices such as “upcoding,” in which patients’ health problems are overstated to get larger sums from Medicare. Assessing the waste from employer-based insurance is harder, but most evidence suggests that private insurers have substantially higher administrative costs than Medicare does. Furthermore, the complexity of private insurance, with multiple payers all trying to deny care when they can, is a huge burden both on providers — doctors, nurses, and hospitals — and on patients. What do private insurers offer to compensate for these costs? One must go through intellectual contortions to avoid the conclusion that they are, in fact, parasites. Which brings me back to El-Sayed. In supporting Medicare for All, he’s basically calling for an end to the partial, parasitic privatization of a healthcare system that is already hugely dependent on public funding. When one looks at it that way, it’s not at all a radical proposal. Admittedly, the political lift requires overcoming the opposition to higher taxes to pay for Medicare for All. Political realism rather than economics was the reason I and many other progressives supported Obamacare, with all its complexities, rather than demanding an immediate move to Medicare for All. But the political calculus may very well have shifted since the 2000s, as Americans are fed up with a system of unaffordable premiums, rampant claim denials, and byzantine claim administration. Moreover, funding healthcare insurance through taxation would allow for a much more progressive distribution of the cost. That is, compared to the present system, middle-income households would pay less as high-income households would pay more. And the U.S. would stop wasting large sums on pointless administrative costs. So let’s be clear: El-Sayed’s healthcare platform is perfectly reasonable on the merits of cost, fairness and health efficacy. And with private insurers never more hated, while millions of Americans are losing their health insurance, 2026 may be its time. MUSICAL CODA
Agency offering disaster loans to businesses
The U.S. Small Business Administration has announced the availability of low-interest federal disaster loans for eligible small businesses and private nonprofit organizations impacted by ongoing drought in areas of the
Millennium Hotels and Resorts Partners with HXE to Strengthen Global MICE Business Through Digital Innovation
Millennium Hotels and Resorts (MHR), a global hospitality leader with a portfolio spanning key destinations worldwide, has entered into a Strategic Partnership Program agreement with HXE in Singapore. The partnership combines MHR's global hospitality network with HXE's digital MICE platform to create new opportunities for corporate meetings and events while supporting the growing demand for seamless, technology-enabled event planning.
Cardinal Commerce Notes: Lynchburg-based BWXT to sell medical business
Plus: Virtual hiring fair upcoming, new nuclear simulator report, Lynchburg’s airport gets a $5.3 million grant and USDA designates Virginia localities as drought disaster areas.
The story behind UT Health San Antonio’s ‘Double Helix’
For more than 40 years, the landmark sculpture has reflected discovery, innovation and advances in healthcare in South Texas.
The Emotional Story Behind Connor Swindells’ Determination to Succeed
Shaped by personal loss and resilience, Connor Swindells transformed heartbreak into motivation, pursuing his ambitions with determination while honoring the family members who inspired him to take ch...
Hurricane Hunter data reveal early signs of strengthening tropical cyclones
Nearly three decades of airborne radar observations identify four features that help storms align before they intensify
Where undergrads grow into scientists
Deep in the woods of in Petersham, Mass., ecologists are cultivating a renewable resource — future generations of scientists. For three decades, the Harvard Forest Summer Research Program in Ecology has prepared undergraduates from around the globe for careers in the sciences.
Judge orders ex-business manager to pay over $11,490 to school in Key West
A 60-year-old woman who was accused of stealing from a private school in Key West — as she allegedly abused her position as a business manager until 2014 — was behind bars on Monday in Monroe County, records show.
Saber's newest game trailer takes a shot at Gearbox's CEO, if you look closely
The first hint that something might be up with the recent debut trailer for Saber Interactive’s Rideshare Stimulator is an unusual choice of words—aside from that second one in the game’s title. “Don’t take your passengers too seriously,” the trailer’s narrator says, as he describes this upcoming game. It a car game about the gig work of driving eccentric people to their destinations, a riff on Crazy Taxi. And then, he says: “When I think I’ve met the randiest of passengers, someone even stranger gets in.” “Randiest”? That suggests “randy,” which usually means having strong sexual desire. Yet none of the oddball backseat occupants featured in the trailer seem particularly lustful. One is an old man who considers his grandson a failure, another shares the theory that birds might control traffic lights, another says he’s banned from an aquarium. A little later, there’s a license plate, shown 63 seconds into the trailer, on the front of an SUV: USB DRV It’s a Texas plate. The symbol between those letters is a cog wheel. If you know, you know. That’s a reference to Texas-based Borderlands game development studio Gearbox Software (their logo features a cog wheel). More specifically, it’s a reference to Gearbox’s CEO Randy Pitchford, who in 2018 found himself explaining the nature of video he’d saved on a USB drive that was found at a Medieval Times restaurant before being returned to the studio: “It was ‘barely legal’ porn. This girl’s handle was ‘Only 18.’” The “girl” in the video had committed a solo sex act that Pitchford, an avid practitioner of magic, found remarkable. “I realized, this is not a sex worker…This is a fucking magician.” Back then, the USB drive was central to competing lawsuits against Gearbox by the studio’s former lawyer and by Gearbox against him. A settlement in late 2019 “exonerated” Pitchford, per the Hollywood Reporter. The USB story has resurfaced at times, now in a trailer from a company that not long ago was corporate brethren with Gearbox. Saber vs. Gearbox The head of Saber told Game File that the reference is payback. “The dig is because Randy took shots at Embracer in Borderlands 4,” Saber CEO Matt Karch told me when I asked him about the license plate. “Without Embracer, Randy is performing magic tricks at birthday parties for a living.” Having interviewed Karch during a cross-country flight in late 2024, I can confirm that Karch was unimpressed with Pitchford during their time both working in the Embracer group. I’d approached him not out of surprise that there was animosity but that it was manifesting publicly now. Gearbox was founded in 1999, worked on a port of Halo early on, and developed hit series such as the loot-based sci-fi shooter Borderlands before it was purchased by The Embracer Group in early 2021 for $363 million (with a possible earn-out of over $1 billion, if certain targets were hit by 2027). Saber was founded in 2001, worked on a remaster of Halo early on, had a big hit with zombie shooter World War Z and was purchased by Embracer in early 2020 for $150 million, with a potential earn-out of up to $375 million. For a few years, the Embracer group was a voracious acquirer of game studios. Then, as investment dried up, it choked. In March 2024, Embracer sold Saber to an investment company controlled by Saber CEO Matt Karch, and it sold Gearbox in an all-stock deal to long-time Borderlands publisher Take Two Interactive. Other studios were shut down. Hundreds of developers were laid off. Gearbox didn’t say much about their Embracer experience, nothing too direct, at least. In the summer 2024, Pitchford told reporter and occasional Game File contributor Nicole Carpenter that Borderlands 4’s story was in some way thematically connected to Gearbox’s experience at Embracer: “There’s this cultural and emotional shift in me, personally, and at the studio. What does it mean to trade some autonomy for organization?” When Borderlands 4 came out, there was something stranger: the matter of “Embracer’s Bluff,” a location in the game featuring an AI-powered toilet and a large trash dump, according to a detailed Kotaku account of the place. Gearbox never commented on it; Take Two never got back to me about it when I asked them last year. By contrast, since Saber exited Embracer, Karch has been one of Embracer’s biggest defenders, casting their management as well-meaning and supportive despite the layoffs and studio closures that resulted from their excessive expansion. Like others, Saber’s Karch saw Embracer’s as a shot. With Rideshare Stimulator’s trailer, he’s returned fire. “It’s amazing to me how fast people forget those who went above and beyond for them,” Karch told Game File. A rep for Gearbox did not comment by press time. Game File is a reader-supported publication. Your backing makes my reporting—including any coverage of trailer-based beefs—possible. Good news! I’m currently running Game File’s first big sale of 2026. You can get a one-year subscription for 23% off. Click here to take advantage of the limited-time offer. And thank you for your support! Item 2: In brief… 🚫 Wal-Mart has laid off the staff of Restart, a games media outlet launched in 2024, Aftermath reports. 🟥 A GTA VI preview is on the way, at last, via an “extended look” that will premiere, unusually, on Netflix at 3pm ET on August 27, then officially go live elsewhere six hours later. Last week, Game File noted that Take Two label Rockstar Games is overdue for showing off GTA VI, based on the timing of the initial hands-off previews of GTA V and Red Dead Redemption 2. During a call with investors, Take Two CEO Strauss Zelnick said pre-orders for GTA VI were “unprecedented and astonishing,” but added the company can’t predict how many of those pre-orders represent bonus sales vs. sales that otherwise would have been made at launch. During the same call, Zelnick was noticeably bullish on the future of playing games over streaming cloud connections (predicting wider adoption in three or so years). He sounded unbothered by Sony’s plans to stop making discs for new games (he said the business is 90% digital already and predicted that there could still be limited edition physical editions of games “in the same way there’s still vinyl in the recorded music business.”) 👀 Take Two wrote off $43 million in their spring quarter after deciding “not to proceed with further development of an unannounced title in its pipeline from a third-party developer.” 🤔 Some rare age-demographics from a big publisher: Capcom recently told investors that “users in their 20s account for approximately half of the users of both Pragamata and Resident Evil Requiem.” Item 3: The week ahead Tuesday, August 11 Game releases: The Elder Scrolls IV: Oblivion Remastered (Switch 2; already out for PC, PS5, Xbox) continues the Bethesda strategy of putting Elder Scrolls games on everything; Royalty Free-For-All is a Smash Bros.-style fighting game featuring public domain characters such as Mother Goose brawling with Oliver Twist in a stage based on the original Little Shop of Horrors movie. Wednesday, August 12 Game release: Pro Jank Footy (PC, console) is an arcade-style Australian Rules Football game with increasingly ridiculous rules, the more you play (I enjoyed the Steam demo) Thursday, August 13 Game release: Super Mario Sunshine (Switch 2, originally released in 2002 on the GameCube) is released for Switch 2’s Nintendo Switch Online service. This game is the black sheep of 3D Mario games. It’s the successor to the breakthrough Super Mario 64 and the rare Mario game built around a single (vacation resort) theme. Mario’s got a water-spraying backpack, a Yoshi pal and a lot of blue coins to collect.
2,400-year-old grave of possible ancient pro wrestler discovered in Turkey
A tomb excavated in Aspendos, Turkey, revealed a skeleton buried with several coins featuring ancient wrestlers.
Ant Colonies Pulse Like a Physical System, And Scientists Are Beginning to Understand What Triggers Them
It starts by activating a lazy co-worker.
Hunter Biden tells Tucker Carlson that Trump poses an ‘existential threat’
Biden has made a point of talking to conservative media figures in recent months.
Community members demand Colorado issue public health order for ICE tuberculosis case
Community advocates called for more pressure from Colorado officials on the private company that runs an ICE detention center.
ICYMI: Bernhard Capital Partners to acquire Virginia engineering firm
Baton Rouge-based private equity firm Bernhard Capital Partners has agreed to acquire Reston, Virginia, engineering and infrastructure services firm Bowman Consulting Group Ltd. in an all-cash transac… Already an INSIDER? Sign in. Already an INSIDER? Sign in
iOS 27 Beta 5 Brings New Icons for Siri, Safari, Settings and More
In the fifth beta of iOS 27, Apple is continuing to make design tweaks. There are updated Liquid Glass icons for Safari, the Siri app, Settings, Remote, App Store, and Preview. The Safari icon is a brighter blue with more detailed compass lines and arrows, while the Siri icon looks more like the actual Siri bubble that's displayed when Siri is activated.
Steelers camp observations: Max Iheanachor remains out, but tackle depth shines on Day 10
Armchair general managers looking to make their 53-man roster projections take note: Mike McCarthy is not opposed to keeping 10 offensive linemen. If the...
Eagles training camp observations: Quinyon Mitchell applies the clamps
Here are our practice notes from Day 9 of Eagles training camp in 2026.
Sporting KC Weekly Schedule: Aug. 10-16, 2026
Sporting Kansas City II News: The official source for all SKC II news, photos, videos, highlights, and more.
Representing Peru at the Student Conference on Conservation Science
MCAF project leader Aurora Maguina Silva shares her experience attending the SCCS conference at the University of Cambridge, England.
Lifeways getting new van to help mental health services in Jackson
Rep. Schmaltz secures funding for innovative van to help people in need State Rep. Kathy Schmaltz has secured $210,000 in the new state budget for LifeWays, the Jackson-Hillsdale Community Mental Health program, to purchase an Innovative Mobile Mental Health Crisis Unit that will expand access to mental health services throughout Jackson County. The innovative unit […]
Bernhard Capital Partners strikes $1B deal to acquire Virginia engineering firm
Baton Rouge-based private equity firm Bernhard Capital Partners has agreed to acquire Reston, Virginia, engineering and infrastructure services firm Bowman Consulting Group Ltd. in an all-cash transac… Already an INSIDER? Sign in. Already an INSIDER? Sign in
Funding Science for the Long Term: The Role of Private Philanthropy
A drug that reaches a pharmacy shelf today often rests on discoveries made decades earlier. Yet the institutions financing scientific research do not
Scientists Release Biggest 2D Map of the Universe
Key Takeaways The DESI Legacy Imaging Surveys combined more than 263,000 telescope exposures to make the largest 2D map of the universe in visible and near-infrared light. Astronomers can pair the Legacy Surveys map with their own observations to explore our universe and search for rare phenomena. The 2D map serves as the foundation for the Dark Energy Spectroscopic Instrument survey to measure the universe in 3D and investigate dark energy. Hold on to your telescopes: the DESI Legacy Imaging Surveys team has released the largest-ever 2D color map of the universe. The 5.6-trillion-pixel map contains nearly 4 billion celestial objects, primarily stars and galaxies. The data is available for all to use and publicly viewable through the Legacy Survey Sky Viewer. Astronomers and citizen scientists can explore the map or combine it with their own observations to better understand our universe. Researchers can search for rare phenomena like gravitational lenses, observe fleeting events like supernovae, and investigate two of physics’ biggest mysteries: dark matter, the invisible substance that accounts for most of the mass in our universe, and dark energy, the force driving our universe’s accelerating expansion. The new map builds on earlier versions from the DESI Legacy Imaging Surveys that have already proved invaluable. To date, more than 1,800 science papers that reference the Legacy Surveys data have been published. “It’s part of the fabric of astronomy research now,” said David Schlegel, a co-lead of the Legacy Surveys and scientist at the Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab). “When you’re working with astronomical objects today, you often start by pulling up the Legacy Imaging Viewer to see what you’re looking at.” Covering roughly 75% of the sky in visible and near-infrared light, the updated map provides a deep view of the extragalactic universe not blocked by the dust and stars of our own Milky Way. Researchers expect it will remain the most comprehensive 2D map of our universe for years to come. More than 160 scientists contributed to data collection for the project, and a team of 20 produced the final dataset released today. It was built by combining 263,407 telescope exposures from three ground-based sky surveys: the Dark Energy Camera Legacy Survey (DECaLS) at NSF Cerro Tololo Inter-American Observatory, the Mayall z-band Legacy Survey (MzLS) at NSF Kitt Peak National Observatory, and the Beijing-Arizona Sky Survey (BASS) at the University of Arizona’s Steward Observatory. That was supplemented by years of data from NASA’s Wide-field Infrared Survey Explorer (WISE) satellite mission and additional public data. “For our team, these data are fundamental to our investigation of the expansion history of the universe and the formation of our galaxy,” said Arjun Dey, co-lead of the Legacy Surveys and an astronomer at NSF NOIRLab. “But the skies belong to everyone, and this survey gives everyone the chance to explore the sky and marvel at its wonders.” Here be galaxies The DESI Legacy Imaging Surveys were originally conducted to prepare for the Dark Energy Spectroscopic Instrument (DESI) survey. The Legacy Surveys’ 2D map is essentially a deep photograph of the sky; it records where galaxies and stars appear and how bright they appear. This crucial step enables DESI to select objects and measure their light in different wavelengths to determine their distances, building the largest high-resolution 3D map ever made. Scientists study the way galaxies have clustered at different ages of the universe to track dark energy over time. In April 2026, DESI completed its original five-year survey ahead of schedule and with vastly more objects than expected. The early results have shown surprising hints that dark energy’s impact may be weakening over time — a paradigm shift that could potentially shape the predicted fate of our universe. DESI expects to publish improved results using their first five years of data in 2027 and is continuing observations into 2028. DESI was so efficient at observing galaxies, the Legacy Surveys map needed to expand. Early on, “it became clear we might run out of galaxies to look at and run out of sky, and we better start doing something about that,” said Schlegel, who also works on DESI. The new Legacy Surveys map has been used to select DESI targets since June 2026 and will guide the telescope’s operations over the coming years. Computing the cosmos Merging hundreds of thousands of images taken on 2,285 nights, each with unique atmospheric and telescope conditions, was a massive computational effort. It took about a year to develop the computer code and eight weeks to process all the images at the Perlmutter supercomputer at the National Energy Research Scientific Computing Center (NERSC) at Berkeley Lab. Beyond supporting DESI, the Legacy Surveys will be a foundational reference for the next generation of telescopes. As new observatories like the NSF-DOE Vera C. Rubin Observatory (jointly funded by NSF and DOE’s Office of Science) and NASA’s Nancy Grace Roman Space Telescope come online, researchers can compare their observations with one of the deepest and most comprehensive views of the sky ever assembled. The Legacy Surveys data will also help scientists train artificial intelligence tools to analyze petabytes of astronomical data and accelerate new discoveries. It will be among the datasets used in an astrophysics pilot project within the American Science Cloud, part of the DOE’s Genesis Mission. The DESI Legacy Imaging Surveys are supported by the U.S. Department of Energy’s Office of High Energy Physics; the National Energy Research Scientific Computing Center, a DOE Office of Science user facility; the U.S. National Science Foundation, Division of Astronomical Sciences; and the partner institutions. DESI is supported by the DOE Office of Science and NERSC. Additional support for DESI is provided by the NSF; the Science and Technology Facilities Council of the United Kingdom; the Gordon and Betty Moore Foundation; the Heising-Simons Foundation; the French Alternative Energies and Atomic Energy Commission (CEA); the Secretariat of Science, Humanities, Technology and Innovation (SECIHTI) of Mexico; the Ministry of Science and Innovation of Spain; and by the DESI member institutions. ### Lawrence Berkeley National Laboratory (Berkeley Lab) is committed to groundbreaking research focused on discovery science and solutions for abundant and reliable energy supplies. The lab’s expertise spans materials, chemistry, physics, biology, earth and environmental science, mathematics, and computing. Researchers from around the world rely on the lab’s world-class scientific facilities for their own pioneering research. Founded in 1931 on the belief that the biggest problems are best addressed by teams, Berkeley Lab and its scientists have been recognized with 17 Nobel Prizes. Berkeley Lab is a multiprogram national laboratory managed by the University of California for the U.S. Department of Energy’s Office of Science. DOE’s Office of Science is the single largest supporter of basic research in the physical sciences in the United States, and is working to address some of the most pressing challenges of our time. For more information, please visit energy.gov/science.
When politics becomes a duel
The Burr-Hamilton clash showed how humiliation and revenge could turn public rivalry into private ruin, leaving a republic with nothing gained.
Direct Relief and The Pfizer Foundation Expand Support for Community Health Centers on the Front Lines of Infectious Disease Care
This spring, Direct Relief and The Pfizer Foundation announced the third cohort of the Innovation Awards in Community Health.
Eleven Arkansas students place in 2026 Soybean Science Challenge
Eleven Arkansas students earned honors in the 2026 Soybean Science Challenge for innovative agricultural research and sustainable projects.
Encompass Health announces launch of private offering of 5.875% senior notes due 2034
/PRNewswire/ -- Encompass Health Corp. (NYSE: EHC) today announced it has commenced a private offering of an additional $100 million in aggregate principal...
AbCellera women’s health data top ‘most aggressive upside scenario,’ putting Astellas and Bayer on notice
AbCellera has reported phase 2 results “beyond even the most aggressive upside scenario” that its CEO dared to consider, boosting the biotech’s chances of challenging Astellas and Bayer for a women’s health market. The phase 2 clinical trial compared ABCL635, an antibody targeting NK3R, to placebo in patients with hot flashes caused by menopause. Investigators enrolled 92 postmenopausal women experiencing a mean of about 10 moderate or severe hot flashes per day. By Week 4, the number of moderate or severe hot flashes had fallen by a mean of 8.8 on ABCL635 and by 3.5 on placebo. That statistically significant, placebo-adjusted reduction of 5.3 hit the trial’s primary endpoint. The level of efficacy also cleared the bar set by existing drugs. While cross-trial comparisons can be misleading, AbCellera CEO Carl Hansen, Ph.D., had seen enough to start hyping the program. “We now view ABCL635 as a potential best-in-class non-hormonal therapy with strong differentiation against approved NK3R competitors across all important dimensions, including efficacy, safety, dosing and convenience,” Hansen said on a Monday morning conference call with investors to discuss the data. “We believe ABCL635 is now a highly de-risked program.” Last week, Hansen used AbCellera’s earnings call to set expectations for readout, with the CEO defining success as a clean safety profile and efficacy comparable to the two approved small molecules. The data vaulted over that bar. Astellas linked (PDF) one of the small molecules, Veozah, to placebo-adjusted reductions in hot flash frequency of 2.1 and 2.6 at Week 4 of its two phase 3 trials. Bayer reported (PDF) placebo-adjusted reductions of 3.04 and 3.29 at Week 4 of pivotal studies for its small molecule, Lynkuet. At 5.3, the placebo-adjusted reduction in AbCellera’s trial comfortably cleared the standard set by the incumbents. Veozah and Lynkuet came to market based on evidence of their ability to reduce the frequency and severity of hot flashes. AbCellera’s phase 2 study covered both endpoints, with the Canadian biotech reporting a mean reduction in severity of 1.4 points at Week 4 on ABCL635, compared to 0.3 points for placebo. Again, the placebo-adjusted result compares favorably to data on Veozah and Lynkuet. Analysts shared Hansen’s enthusiasm for the data. The phase 2 results “firmly validate ABCL635 as a potentially best-in-class treatment,” BMO Capital Markets analysts said in a note to investors Monday. ABCL635’s apparent efficacy edge “is likely attributable to the higher dosing/target engagement the asset is able to reach vs. the oral agents due to its wider therapeutic index,” the analysts added. The analysts, who model $2.3 billion in unadjusted peak sales for ABCL635, flagged the safety profile as another positive of the phase 2 readout. While Veozah carries a boxed warning for liver damage, nobody on ABCL635 in the phase 2 trial had elevated liver enzymes or bilirubin values. If replicated in phase 3, the lack of a liver signal could allow approval without the monitoring requirements imposed on Veozah. Investors appeared equally enthused, sending AbCellera's stock up 32% to $9.21 in premarket trading Monday from a Friday closing price of $6.93. Next, AbCellera will collect the Week 12 data and talk to its advisors about further development. The results open up “a wide variety of possibilities of how we might take this forward into phase 3 studies to truly maximize the value of the asset and make sure that ABCL635 is able to demonstrate its differentiation potential,” Sarah Noonberg, M.D., Ph.D., AbCellera’s chief medical officer, told investors.
Science and Innovation Fund for Ukraine Partners with Ukrainian Catholic University to Launch New Center of Excellence
The Science and Innovation Fund for Ukraine and the Ukrainian Catholic University have announced the establishment of the Center of Excellence in Formal Methods and Verification, a new initiative that will train a new generation of specialists across the fields of mathematics, computer science, and artificial intelligence.
Blue Shield of California Appoints Healthcare Innovation Leader Kedar S. Mate, MD, to Board of Directors
"Kedar has spent his career helping healthcare organizations deliver better outcomes for the people they serve."
Instacart and Academy Sports + Outdoors Team Up for Same-Day Delivery in as Fast as an Hour
Customers can now shop Academy's national and exclusive private brands across sports, outdoor, apparel, footwear and more at no markups SAN FRANCISCO and KATY, Texas, Aug. 10, 2026 /PRNewswire/ -- Instacart (Nasdaq: CART), the leading grocery technology company in North America, today announced a
Trump admits 'contractor error' on Lincoln Memorial Reflecting Pool
For the first time, Trump admitted there was a construction error on the Lincoln Memorial Reflecting Pool, which is seeing another round of costly renovations.
Monday’s AI business surges, but investors send shares down
AI ARR doubled from Q1 and accounted for 17% of net new ARR, but the company forecast conservative growth for the third quarter and did not raise its annual guidance.
The sun will vanish over Europe in a rare total solar eclipse: Watch live
A total solar eclipse will plunge parts of Europe into darkness on August 12, 2026, with Spain offering some of the best views. ESA will livestream the spectacle from the Javalambre Observatory, combining telescope feeds, drone footage, and expert commentary. At 20:31 CEST, the observatory will experience 1 minute and 21 seconds of totality, revealing the Sun’s normally hidden outer atmosphere.
Michigan Athletics to Host Elevate HER Summit
The University of Michigan Athletic Department will host the Women in Sports: Elevate HER Summit on Thursday, Oct. 15, at Crisler Center on the Stephen M. Ro...
Roads and dams put European eels at risk, scientists offer strategy to save them
An international team of scientists have put forth recommendations, published in Global Ecology and Conservation, for conservation strategies that could save the species from extinction .