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Health educator earns 2026 national honor
National Academy of Health and Physical Literacy spotlights Lori Reichel for health literacy advocacy.
The Supreme Court’s conservatives could significantly alter the 2026 election
The Supreme Court on Monday appeared ready to limit mail-in ballots, a move that would reinforce the justices’ pattern of shrinking voter protections and that has, at bottom, favored Republican interests and the Trump administration.
Why REI treats CX as a critical business function
The outdoor retailer is focused on doubling down on its differentiators, REI’s Clay Walton-House said. That means investing in its elevated services and member experience.
Freeway series game II chat
The Dodgers play their first game at Dodger Stadium since Game 5 of last year’s World Series on Monday, hosting the Angels for the second of a three-game exhibition series. Roki Sasaki goes for the Dodgers against left-hander Reid Detmers. MONDAY GAME INFO
NIU Today - Two business graduate degrees reimagined with a bold AI focus
Beginning this fall, two graduate degrees within the College of Business’s Department of Operations Management and Information Systems (OM&IS) will be reimagined to emphasize their focus on artificial intelligence and analytics. Formerly known as the Master of Science in Data Analytics (MSDA) degree, this degree has been transformed into the Master of Science in Business...
Revolutionary Women: Lady Johnson, Angelica Schuyler and the Politics of Loyalty
State and territory commissions and other partners are hosting events across the nation to commemorate America's 250 anniversary in 2026.
UCI Health lays off 150 workers as part of restructuring
UCI Health said the cuts were prompted by a changing environment that includes shifts in federal funding, reimbursement pressures and rising operational costs,
Trump administration to pay French company $1B to walk away from US offshore wind leases
The Department of Interior says a French energy company has agreed to give up two U.S. offshore wind leases and invest in fossil fuel projects instead.
German men's biathlon coaches stay, women's coaches leave after flop
Tobias Reiter und Jens Filbrich have kept their jobs as coaches of Germany's men's biathlon team despite their equivalents in the women's team leaving their roles. The season which finished on Sunday was hugely disappointing for the former biathlon powerhouses, with just one Olympic bronze medal and no World Cup wins.
Experience shone through for Manchester City at Wembley against Arsenal
Manchester City claimed the first piece of silverware for the 2025/26 season with their 2-0 win over Arsenal at Wembley in yesterday’s Carabao Cup final. A second half brace from Nico O’Reilly was...
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
New Apple TV and HomePod Mini Remain 'Ready' to Launch
Apple has unveiled nine new products this month, but the wait continues for the next-generation Apple TV 4K and HomePod mini models. In his Power On newsletter today, Bloomberg's Mark Gurman said new versions of the Apple TV and HomePod mini have been "ready" since last year, but he reiterated that Apple has held off on releasing them until the more personalized version of Siri and other Apple Intelligence upgrades are released later this year.
Core operating profit rises 4% as net profit holds steady, with full-year dividend maintained at HK35 cents
March 22, 2026 -- The Hong Kong and China Gas Company Limited (stock code: 0003, hereinafter referred to as “the Group”) has announced its 2025 ...
Slovenians head to polls in tight race marked by spy scandal
Allegations of espionage and foreign interference have cast a shadow over the parliamentary election
NCAA tournament takeaways, Day 3: Big Ten reigns supreme, 'Cinderella' Texas and an extra edge for Houston
‘They want to colonise us’: Brazil’s Lula warns of foreign interference
The left-wing Brazilian president is critical of US actions throughout Latin America, though he does not name Trump.
Tottenham eye transfer move for Freiburg’s Noah Atubolu
Tottenham Hotspur have watched Freiburg’s Noah Atubolu as they search for goalkeeping reinforcements this summer, according to the Daily Mail.Tottenham need a new goalkeeper, with Guglielmo Vicario ...
Are team sports the secret to living longer?
How a basketball league for “grannies” is reimagining aging.
More Subnautica 2 legal trouble brewing amid claims Krafton "intentionally leaked" May release without consulting reinstated CEO
Lawyers for Subnautica 2 studio's newly reinstated CEO are reportedly pushing for Krafton to be found in contempt of court after it "leaked" a May release.
In Reversal, Trump Reinstates Support For Representative Jeff Hurd
President Trump reinstated his endorsement of Representative Jeff Hurd of Colorado, just weeks after pulling it back.
Four Key Moments: Hearing on Improving Kidney Health Through Better Prevention and Innovative Treatment
WASHINGTON, D.C. – Medicare’s coverage and reimbursement policies for chronic kidney disease (CKD), and its most severe form, end-stage renal disease...
Pete Hegseth's Christian rhetoric reignites scrutiny after the U.S. goes to war with Iran
Hegseth has pushed policy changes that reflect his Christian views, including a revamp of the military chaplain corps.
Letai: “From this point forward, it really is much more like business as usual at the NCI.”
NCI Director Anthony Letai appeared before the National Cancer Advisory Board Committee March 17 to maneuver through thorny topics while reiterating his message of reassurance: Stability. Stability. Stability. NCI is sturdy and will weather the storms. “The mission hasn’t changed at the National Cancer Institute,” Letai said in his remarks to the committee. “The resources […]
Spiking diesel prices force WA businesses to make tough choices
Drivers, trucking firms and other shipping companies worry the rise in diesel prices will reignite inflation and force many operators out of business
Trump’s global agenda flies into domestic headwinds
Even as US President Donald Trump calls for international support for the war in Iran, within the US there are dissenting voices, as not everyone is convinced that war is the answer. What is clear is that domestic factors will increasingly limit Trump’s foreign policy and diplomatic engagement. Academic Derek Grossman discusses the issue.
David Lynch heaps praise on ‘absolutely brilliant’ Liverpool star
Liverpool 4-0 Galatasaray: Dominik Szoboszlai Leads Ruthless Charge into Champions League Quarter-FinalsLiverpool’s emphatic 4-0 win over Galatasaray at Anfield has reignited belief, and much of tha...
New dispute emerges around Subnautica 2’s early access release
Lawyers for the ousted—and now partially reinstated—leadership team of Unknown Worlds, the studio behind Subnautica 2, are crying foul over news that the game will be released into early access in May. The release announcement earlier this week was made improperly, potentially “damaging the game and sowing additional confusion among the Subnautica community,” the lawyers said in a letter sent on Tuesday to Vice Chancellor Lori Will of Delaware’s Court of Chancery. In their letter, the lawyers also floated the idea of asking Will to find Krafton in contempt of the court’s ruling. The letter was sent just one day after Will’s bombshell ruling that publisher Krafton had breached its contract with Unknown Worlds’ executive team, when it fired them last June. The new issue isn’t necessarily the May early access timeframe, but how the news was announced. The letter and Krafton’s response have not been previously reported. A quick recap of prior events: Subnautica 2 is an unreleased, underwater survival adventure and the most-wishlisted game on Steam. Last year, longtime Unknown Worlds CEO Ted Gill, along with studio co-founders Charlie Cleveland and Max McGuire, were fired by Krafton. They swiftly sued, saying the publisher had terminated them to avoid paying out up to $250 million in potential performance-based bonuses. The studio leaders had hoped to earn that with an early access release of the game, which Krafton had blocked. The publisher argued in court that Subnautica 2 wasn’t ready, which the ousted execs disputed. On Monday, Will ruled that Krafton had violated its contract, firing the execs to avoid the performance payouts, and that it had to reinstate Gill and give him full authority over any early access release for Subnautica 2. On Tuesday, IGN reported on a new memo issued that day to Unknown Worlds staff by Steve Papoutsis, the executive Krafton had put in charge of Unknown Worlds after the 2025 firings. In the note, Papoutsis said that Subnautica 2 had passed a key development milestone “last week” and that he and Krafton had determined the game “is ready for Early Access release in May.” This news appeared to catch the lawyers for Gill, Cleveland and McGuire by surprise. On Tuesday night, they sent a letter to Will expressing “serious concerns” about whether it would be possible to forge an agreement with Krafton consistent with the judge’s order. Papoutsis’ memo was a problem, they wrote. He didn’t have the authority to declare anything about Subnautica 2’s release. As of 9am ET on Monday, March 16, the effective date of Will’s order, Papoutsis wasn’t CEO of Unknown Worlds. Gill was. And, per Will’s order, only Gill could make Subnautica 2 release decisions. They continued: Krafton self-servingly announced the launch without any regard to its impact on the game, the team, or the community—let alone this Court’s Opinion. Announcing the release of a game is momentous, and it is typically accompanied by significant marketing activity, fanfare, and community coordination. And most importantly, the announcement is carefully designed to maximize excitement for the game. That entire process was supposed to be driven by Mr. Gill. However, in defiance of the Court’s Opinion, Krafton has now taken that away, further damaging the game and sowing additional confusion among the Subnautica community. The lawyers speculated that Krafton had “intentionally leaked” Papoutsis’ memo and then issued an official statement to confirm the leak. Game File is a reader-supported publication. My reporting is only possible through support from readers like you. To support my work, consider becoming a free or paid subscriber. Subscribe On Wednesday, lawyers for Krafton defended their client in their own letter to vice chancellor Will, saying nothing they did violated her order nor showed contempt: Papoutsis’s message was simply celebrating the UW employees’ efforts toward a past event: Krafton’s pre-Opinion determination that Subnautica 2 was ready for Early Access release. There was nothing improper about conveying the results of the milestone review or thanking the development team for their dedication and talent. They added that Gill could still make his own call about Subnautica 2’s release: In his role as CEO, Gill will be able to assess independently his views on the state of Subnautica 2 and the appropriate release schedule; nothing in Papoutsis’s message alters Gill’s authority or discretion. Vice chancellor Will has not responded to the letters and doesn’t necessarily have to. Both parties were previously ordered by Will to confer this week and submit a proposed judgment consistent with her ruling. The letter from Gill’s attorney’s this week doesn’t indicate whether he would or would not support a May release for Subnautica 2. But it could limit his options. And, if Gill’s lawyers are right, the lack of marketing fanfare around the leak of the May date could dull the launch of the game. Any harm to Subnautica 2’s launch is an extra sensitive issue given the context of the legal dispute: millions of dollars of payouts are on the line, tethered to the scale of the game’s initial performance. In her ruling on Monday, Will noted that there was obvious “bad blood” between Gill’s side and Krafton but that the two would need to work together: “They can—and must—act in good faith to navigate their remaining contractual relationship.” Item 2: A new kind of couch co-op game A highlight of GDC each year is the Alt.Ctrl showcase that features games played with extremely experimental controllers. Perusing this year’s offerings last Friday, I found a game controlled with giant scissors, another with big toothbrushes and one that amounted to dumpster diving. My favorite was Pivot, a co-op game about collectively maneuvering a couch. It was developed by students at the University of Utah’s masters of arts and engineering games program. Players lift and tilt the physical couch in order to control the position of a virtual one. That virtual one is moving through an obstacle course on-screen, while being pursued by a giant skull. Developer Nishant Verma told me at GDC that the couch is made of styrofoam (this became more evident as I watched!) and that the name was a riff on an episode of the sitcom Friends. Item 3: In brief… 🚫 Ubisoft is laying off more than 100 workers at its Red Storm studio, as the North Carolina location known for decades for its Tom Clancy games, ceases in-house game development, VGC reports. 👀 On Monday, Nvidia’s revealed its DLSS 5 AI-driven graphics technology that purports to improve game graphics… and it has been roasted about it by the media and the online gaming public for the remainder of the week. The tech changed the faces of characters in footage from Resident Evil Requiem, Hogwarts Legacy and EA Sports FC, drawing accusations of giving carefully art-directed games the generic look of AI “slop.” Nvidia CEO Jensen Huang had said on Monday that “DLSS 5 is the GPT moment for graphics—blending handcrafted rendering with generative AI to deliver a dramatic leap in visual realism while preserving the control artists need for creative expression.” By mid-week, Huang was telling Tom’s Hardware that the new tech’s critics were “completely wrong” because game-makers could still “fine-tune the generative AI” to suit their game’s aesthetics.
Joe Kent's resignation over Iran war reignites antisemitism fears and debate over Israeli influence
It was no surprise when Joe Kent showed up on Tucker Carlson’s podcast a day after quitting his counterterrorism job in President Donald Trump’s administration. But before long, the conversation moved in a different direction as Kent nodded to conspiracy theories that pro-Israel forces were behind the assassination of conservative activist Charlie Kirk.
To chop spending, Ottawa will cut science, tourism, foreign aid programs
While 40 departments will collectively spend $23 billion more next year, another 85 departments will spend $31 billion less in 2026-27.
Phillies and Aramark Sports + Entertainment Announce What’s New in the 2026 Food Experience at Citizens Bank Park
With just one week until the reigning, back-to-back NL East champions return for the home opener, the Philadelphia Phillies and Aramark Sports + Entertainment today announced an exciting new lineup of food offerings and experiences coming to Citizens Bank Park for the 2026 season. Highlights include the debut of new
Ban corporate donations to UK political parties to protect elections, says thinktank
CenTax warns bill under debate in parliament has ‘easily exploitable’ loopholes and will not prevent foreign interference
UW Health resident creates adaptive crayons for children with disabilities
MADISON, Wis. — A physical medicine and rehabilitation resident at UW Health is reimagining crayons by creating adaptive crayons for people with developmental disabilities, stemming from her past experiences.
Medicaid drug reimbursements could end for health care providers across Indiana
Health centers warn they could lose millions in rebates under the states proposed change, which would end Medicaid drug rebates for health organizations.
Bill on foreign influence in Georgia politics returns to Senate
The Georgia House passed a bill requiring disclosure of political spending from countries designated as hostile foreign adversaries, with a 98-65 vote largely along party lines.
Roundup: Amazon / Wholesale prices / Foreign threat response
Cutting USPS use: Amazon plans to slash its use of the U.S. Postal Service by at least two-thirds as its delivery contract expires, potentially stripping billions in revenue from the agency. The shift follows a new bidding process for last-mile delivery and could leave USPS with excess capacity, forcing cost cuts as it searches for […]
Trump waives Jones Act for 60 days in bid to free up the flow of oil to US ports
President Donald Trump temporarily waived the century-old shipping law for 60 days, allowing foreign ships to carry oil and resources between U.S. ports.
Matt Strahm Full Game Log
View Matt Strahm's full Game Log from the null MLB season
Colorado lawmakers want to rein in sports betting
The legislation acknowledges an increase in problem gambling since the state legalized it in May 2020.
Gilgeous-Alexander scores 40 as Thunder clinch playoff berth
Shai Gilgeous-Alexander delivered a 40-point scoring performance as the Oklahoma City Thunder became the first team to punch their ticket to the NBA playoffs with a 113-108 defeat of the Orlando Magic on Tuesday.Reigning NBA Most Valuable Player Gilgeous-Alexander saluted the Thunder's resilience after a mixed first-half performance.
Cuban American business owners in South Florida react to the island's announcement to allow foreign investment
Subnautica 2 publisher’s CEO used ChatGPT in failed bid to avoid paying US$250m bonus to own studio head, court hears
Court orders Krafton’s CEO to reinstate Unknown Worlds’ leadership after they were ousted using an AI-generated plan
A gaming CEO asked ChatGPT how to avoid paying a $250 million bonus. It didn’t work
Krafton's AI-assisted scheme to oust the makers of Subnautica 2 just collapsed in court after a judge ruled the company had to reinstate the CEO and payout the bonus.
Trump’s Gutting of Election Security Fuels Worries for Midterms
Officials say the crippling of the Cybersecurity and Infrastructure Security Agency, which the president himself created, could open elections to cyberattacks and foreign influence.
Environmental science student earns prestigious internship at Germany’s Freiburg University
Nelly Koz has always made an impact in her community through her love of the outdoors. Now, she’ll have a chance to make an impact on a global level. The environmental science major recently accepted a lucrative internship at Freiburg University in Germany, where she will help with data collection and recording observations on a section of the Black Forest that serves as a living laboratory.
Krafton responds to Subnautica 2 legal ruling: "we are evaluating our options as we determine our path forward"
Krafton has issued a statement in response to a legal ruling yesterday, which pushed for CEO Ted Gill to be reinstated to the Subnautica 2 studio.
Southeast Asian Fuel Prices Destabilize Politics
Indonesia, for one, has a bloody history of fuel-related riots.
Cuba tells exiles ‘doors are open’ to invest in businesses in the country
Cuba also says it is removing impediments to US businesses and other foreign investors.
This unified approach helps put effective healthcare AI into practice
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Supreme Court to review Trump’s effort to end deportation protections for migrants from Haiti and Syria
The Supreme Court announced Monday it will decide whether President Donald Trump can terminate temporary deportation protections for hundreds of thousands of foreign nationals, agreeing to hear arguments next month on an issue that has been central to the administration’s immigration agenda.
Red-hot teams clash when Hurricanes visit Blue Jackets
Andrei Svechnikov and Sebastian Aho look to continue their respective strong play on Tuesday as the Carolina Hurricanes visit the streaking Columbus Blue Jackets.
Bombshell judgment demands Krafton immediately reinstate ousted CEO and return his authority over Subnautica 2
In a bombshell ruling, a court has ordered Krafton to reinstate former Unknown World CEO Ted Gill, return control of th…
Judge delivers bombshell order for Krafton to reinstate fired Subnautica 2 devs and CEO, putting $250m bonus package back on the table
A judge has ruled that fired Subnautica 2 leads including the former Unknown Worlds CEO must be reinstated, with their $250m bonus package extended.
EHR fragmentation offers an opportunity to enhance care coordination and experience
Harmonizing electronic health record platforms and their legacy data tames complexity and enables easier patient access to information and greater patient trust in the healthcare system, says NewYork-Presbyterian's EHR manager.
Judge Orders Subnautica 2 Studio CEO Reinstated Amid Lawsuit
Krafton is "enjoined" from firing Ted Gill as part of a new court order
Iran's Political Prisoners Are in Danger From U.S.-Israeli Strikes
Thousands of detainees are in danger from U.S. and Israeli strikes and Tehran’s vengeance.
Play-off dream back on for Stoke?
Final Score's Sam Fletcher reflects on an important win for Stoke City and how it could reignite their promotion ambitions.
Soap operas, reimagined
The fastest-growing entertainment format in America does not live on Netflix or network television. It lives on your phone
Gulf investors seen likely to keep funding Africa renewable energy despite the Iran war
Renewable energy projects in Africa that depend on Middle Eastern sovereign wealth funds and state-backed companies will likely press ahead despite the Iran conflict, analysts say, thanks to the continent's surging appetite for power and fuel.
Jane Fonda Questions Why Barbra Streisand Paid Tribute to Robert Redford at Oscars Instead of Her!
If Trump has already won the Iran war, why does he need foreign ships to help him end it?
A week ago, President Donald Trump told Britain not to bother sending ships to the Middle East because he’d already won the Iran war.
Billy Crystal Delivers Emotional Tribute To Rob Reiner At The Oscars: The ‘Loss Is Immeasurable’
The “When Harry Met Sally” star was later joined by a slate of actors paying respects to the legendary director at the 98th Academy Awards.
Billy Crystal and Barbra Streisand lead an expanded Oscars in memoriam
The in memoriam at the Oscars honoring those in the film industry who have died spotlighted Rob Reiner and Robert Redford with personal tributes from Billy Crystal and Barbra Streisand.
Oscars unite 17 Rob Reiner stars for emotional tribute: Here's who appeared on stage
Oscars untied a supergroup of Rob Reiner actors for an emotional tribute on stage. Here's who appeared at the Academy Awards, from Demi Moore and Kathy Bates to Meg Ryan and Billy Crystal.
How Foreign-Trained Health Workers Saved the NHS £14 Billion
This blog is part of a series focused on the UK’s recruitment of foreign-trained health workers. This first blog details the amount of money the UK’s National Health Service (NHS) has saved by recruiting foreign-trained health workers. The second blog examines whether this saving is offset by foreign aid contributions to health systems strengthening (HSS) and human resources for health (HRH) in countries of origin.
Strengthening One Health Field Epidemiology Capacity in the WHO South-East Asia Region
Recent public health emergencies—including the COVID-19 pandemic, recurrent zoonotic disease outbreaks, and the high level of antimicrobial resistance—have underscored the urgent need for strong, multisectoral field epidemiology capacities. This reinforces the importance of a workforce equipped with One Health field epidemiology competencies. To address this need, WHO works with the Food and Agriculture Organization of the United Nations (FAO), the United Nations Environment Programme (UNEP), and the World Organisation for Animal Health (WOAH), as part of Quadripartite Alliance for One Health, to strengthen field epidemiology training programmes using a One Health approach.These efforts are aligned with WHO SEARO’s Strategic Framework for Action for Strengthening Surveillance, Risk Assessment and Field Epidemiology and the Regional Roadmap to Advance Field Epidemiology Capacities 2025–2029 emphasize workforce development, multisectoral collaboration, and enhanced preparedness for health emergencies. With funding from the Pandemic Fund, The Competency for One Health Field Epidemiology (COHFE) integration within Field Epidemiology Training Programmes (FETPs) or similar initiatives has been initiated in Bangladesh and India and is planned in Sri Lanka.BangladeshIn Bangladesh, COHFE is being adapted to strengthen the Field Epidemiology Training Programme, Bangladesh (FETP-B) Advanced programme. Initiated in July 2025 and led by the Institute of Epidemiology, Disease Control and Research (IEDCR), the process brought together stakeholders from human, animal, and environmental health sectors, academia, and laboratories.A Multisectoral Working Group (MWG) was established to guide implementation, conduct readiness assessments, and identify opportunities to institutionalize One Health collaboration. Through national multisectoral consultations and a competency prioritization workshop held in Dhaka in November 2025, stakeholders identified priority technical competencies for surveillance, outbreak investigation, data analysis, and risk assessment, alongside functional competencies related to leadership, coordination, and the laboratory–epidemiology interface. The process also surfaced systemic barriers—such as challenges in data sharing and limited joint investigations—enabling targeted recommendations. These outcomes are guiding curriculum revision, the introduction of One Health simulations and joint field exercises, and the development of a national multisectoral mentorship pool, with updated training materials expected to be implemented in the upcoming cohort.Figure 1. Competency prioritization involving multisectoral stakeholders“COHFE represents a significant step forward in operationalizing the One Health approach. The collaboration between national institutions and the Quadripartite partners is critical for building resilient systems to address complex health challenges in the region.”, Prof. (Dr) Tahmina Sirin, Director, Institute of Epidemiology, Disease Control and Research (IEDCR), Bangladesh.Aligning India’s One Health Training with COHFEIn India, the National Centre for Disease Control (NCDC) has strengthened One Health workforce development through its SectorConnect initiative. WHO supported a comprehensive competency mapping and curriculum review to align the Field Epidemiology Programme in One Health (FEP-OH) with all 14 COHFE domains. The review identified strong foundations while generating actionable recommendations to strengthen One Health learning outcomes, expand joint field-based learning, and enhance competency-based assessment. These improvements are informing programme refinement and phased scale-up across additional states.Figure 2. Strengthening learning outcomes for the SectorConnect FEP OH CurriculumThrough these efforts, WHO SEARO will continue to support countries to move from separate sector-based training toward an integrated, impact-driven One Health field epidemiology workforce capable of addressing complex health threats at human-animal-environment interface.ReferencesFood and Agriculture Organization of the United Nations, World Health Organization, & World Organisation for Animal Health. (2024). Competencies for One Health field epidemiology (COHFE) framework. https://www.who.int/publications/i/item/9789240080058World Health Organization. (2023). Strategic framework for action for strengthening surveillance, risk assessment and field epidemiology for health security threats in the WHO South-East Asia Region. WHO Regional Office for South-East Asia. https://www.who.int/publications/i/item/9789290210030World Health Organization. (2024). Regional roadmap to advance field epidemiology capacities in the WHO South-East Asia Region 2025–2029. WHO Regional Office for South-East Asia. https://www.who.int/publications/i/item/9789290229544
Reimagined children’s gallery opens in Fort Worth Museum of Science and History
Cook Children’s Medical Center helped design a new medical play space aimed at making kids less afraid of hospitals.
What are WSJ’s entertainment reporters watching for?
“I’m looking forward to seeing the tribute segment to [Rob Reiner](https://www.wsj.com/arts-culture/film/rob-reiner-director-of-this-is-spinal-tap-when-harry-met-sally-dies-at-78-10f173d4?gaaat=eafs&gaan=AWEtsqcsCM1C96TeMZywXFmpOxqT5r-PI5LtSs21eYXrdWiCfc5MGyZi3A3WA806Yc%3D&gaats=69b46c63&gaa_sig
iOS 27 Will Reportedly Be Like Mac OS X Snow Leopard
In his Power On newsletter today, Bloomberg's Mark Gurman reiterated that iOS 27 will be similar to 2009's Mac OS X Snow Leopard, in the sense that one of Apple's biggest priorities is bug fixes for improved performance and stability. At WWDC 2008, Apple showed a presentation that said Mac OS X Snow Leopard had "0 new features," as it opted to focus on performance and stability improvements.
Iran Foreign Minister Says Mojtaba Khamenei Is in “Perfect Health” After Trump Doubts
Iranian Foreign Minister Abbas Araghchi wrote on his Telegram channel that “the Leader of the Revolution is in perfect health and is ful ...
Player availability report, presented by Orlando Health Orlando Health Jewett Orthopedic Institute: Orlando Pride vs Seattle Reign
Here is this week's player availability report, presented by Orlando Health Jewett Orthopedic Institute, for Sunday's home match vs Seattle Reign
Trump Administration Turns to Migrant Workers to Help Farm Labor Shortage
As the president’s immigration policies squeeze an already tight supply of farm labor, the Trump administration is making it cheaper to hire foreign farmworkers.
Reign crumble against Firebirds in third straight overtime loss
Koehn Ziemmer's two-goal night wasn't enough as the Ontario Reign lose 4-3 in overtime to the Coachella Valley Firebirds Saturday night at Toyota Arena. This is the Reign's first time experiencing three losses in a row this season but they remain in first place in the AHL Pacific Division with 81 points and a record of 38-16-3-2.
2026 Match Guide: Orlando Pride vs. Seattle Reign, presented by Orlando Health
2026 Orlando Pride | Sun, Mar. 15 at 4 p.m. ET | Home Opener
Levett gift backs Science Center’s next phase
The St. Petersburg Foundation has received a $200,000 gift from the Francis and Gertrude Levett Foundation to support educational programming at the reimagined St. Petersburg Science Center.
Entertainment
Discover breaking entertainment news from The Associated Press. AP News has the latest entertainment news including celebrity, music, TV & more.
Kosovo postpones controversial foreign visitor law
The law would have hit Serb nationals as well as ethnic Serbs in Kosovo, benefiting from their services
How Israeli domestic politics affect the Iran war
NPR's Scott Simon asks former Israeli deputy national security adviser Chuck Freilich, now at Columbia University, about Israeli domestic politics and their effect on the Iran war.
Linux Finally Catches Up to Windows with a Game-Changing Performance Feature
For years, the Linux kernel’s scheduler has been world‑class at balancing loads, yet it missed a crucial, cache‑aware instinct. In modern multi‑core systems, that gap can turn into measurable latency, especially when threads bounce between cores that don’t share the same cache. A new upstream feature, often called Cache Aware Scheduling, is now set to change that equation. A cache‑savvy scheduler arrives At the heart of any OS, the scheduler decides which thread runs where and for how long. In modern CPUs, small private caches (L1 and L2) sit beside each core, while a larger Last Level Cache (LLC, typically L3) is shared among groups of cores. When a task migrates across LLC boundaries, its warm data may vanish from the cache, forcing slower trips to main memory. Cache Aware Scheduling keeps related tasks close to their shared LLC, reducing destructive migrations. By respecting cache topology, the kernel minimizes cold‑start penalties and preserves locality that many workloads desperately need. The result is less thrashing, fewer memory stalls, and more consistent throughput. "Keep tasks close to their data, and the system will keep performance close to its peak." Why this narrows the Windows gap Windows has long leaned on topology‑aware, cache‑sensitive heuristics, especially since the Windows 10 era. That advantage helped Microsoft handle hybrid designs with P‑cores and E‑cores, plus complex cluster and NUMA layouts. With cache awareness integrated upstream, Linux brings parity to this vital dimension, without sacrificing its trademark flexibility. The Linux approach remains deeply configurable, reflecting the ecosystem’s breadth across servers, desktops, and embedded devices. It layers atop existing NUMA‑balancing and energy‑aware logic, refining placement rather than reinventing the wheel. Crucially, it aligns scheduling with the hardware’s real shape, not just with abstract CPU counts. Real‑world gains and who benefits Early tests on Intel Sapphire Rapids platforms point to gains in the 30–45% range for select workloads. Those wins appear in cache‑sensitive tasks like in‑memory analytics, high‑thread compilation, and microservices with tight working‑sets. Games and latency‑bound engines can also feel steadier frame‑times, especially when threads share hot assets. The benefits extend to AMD’s 3D V‑Cache parts, where keeping threads near enlarged cache slices prevents needless misses. Hybrid x86 designs with performance and efficiency cores further profit when cache and core roles are scheduled in concert. Even handhelds running SteamOS can squeeze more out of limited power, translating cache locality into smoother play. Key advantages include: Lower end‑to‑end latency Fewer expensive misses to RAM Better multi‑socket and NUMA behavior Improved energy efficiency More predictable QoS under mixed loads Stronger scaling on dense servers Caveats, tuning, and rollout No scheduler change is purely free, and trade‑offs still exist. Favoring locality can reduce cross‑cluster balance if limits are set too tight. Likewise, fairness and utilization must remain healthy, especially under heterogeneous, bursty workloads. Linux’s implementation is designed to be measured and tunable, not a blunt instrument. It cooperates with energy‑aware scheduling for mobile efficiency, and with NUMA‑balancers on big iron. Expect architecture‑specific refinements as vendors surface richer topology hints and cache‑sharing maps. Upstream integration has begun, with broad distribution adoption likely over the next cycles. Many users will encounter the change through standard kernel updates in 2025–2026, depending on distro cadence. Server‑class kernels may enable or tune it sooner for targeted fleets where cache locality is money in the bank. How to think about performance impact Cache Aware Scheduling amplifies gains when your workload is both CPU‑bound and cache‑sensitive. Think tight inner loops, hot code paths, and datasets that fit snugly in shared LLC. It’s less dramatic for I/O‑bound services or memory‑hungry tasks that blow past cache capacity. Still, even modest locality improvements often translate into smoother tail‑latency, which is where user experience and SLAs typically break. Developers can further help by pinning related threads, batching work, and aligning data to reduce cross‑cluster chatter. The scheduler’s new awareness works best when applications expose good hints. The bottom line By understanding and honoring cache topology, Linux removes a subtle yet costly bottleneck. The kernel’s smarter placement keeps hot data hot and work near where it belongs. That narrows a long‑standing gap with Windows, while preserving the openness and tunability Linux champions. For gamers, creators, and operators, the payoff is practical: more consistent frames, faster builds, and snappier services. For the ecosystem, it’s another step toward hardware‑savvy scheduling that turns transistor complexity into real‑world speed. And for Linux itself, it’s a timely upgrade that matches today’s silicon with tomorrow’s expectations.
The NBA's reigning Rookie of the Year is learning a new role: Soccer team owner
As Stephon Castle’s basketball career takes off, he also has an eye on soccer as a minority owner of CT United, a team in Major League Soccer's second division.
Jared Kushner Solicits Funds for His Firm While Working as Mideast Envoy
President Trump’s son-in-law is trying to raise $5 billion or more from foreign governments and others for his private equity firm.
Head injuries, politics and reincarnation: Trump on Jake Paul's podcast
Jake Paul asked Trump about getting into politics as they traded war stories and talked about overcoming adversity on the boxer's inaugural podcast.
Centennial Students Earn 3rd Place at Iowa Regional Science Bowl
Michael Stevens, Ian Anderson, Anna Bruns, Jared Bond, Alice Baghdasaryan and teacher Madison Greif. (Not pictured: Team Manager Vivian Zhang.) Congratulations to our outstanding team for earning 3rd place at the 2026 Iowa Regional High School Science Bowl, held on the campus of Iowa State University on March 7! We’re proud of these students for representing our school with excellence in this challenging academic competition that tests knowledge in science, mathematics, and teamwork.
Vermont’s 8-year ‘all-payer’ health care experiment sunset at the end of 2025. What did it teach us?
The statewide organization at the center of the project, OneCare Vermont, was expensive to launch and operate. Now legislators are trying to reimagine pieces of the program for primary care.
Meta to Shut Down Instagram End-to-End Encrypted Chat Support Starting May 2026
Meta will end Instagram E2EE chats May 8, 2026, reversing a 2021 privacy test and reigniting debate over encrypted messaging oversight.
Brooklyn Nurses Lose Health Care For Weeks Despite $15M From State
The Brooklyn Hospital Center received a fraction of requested aid — and it’s not enough to reinstate more than 400 nurses’ health benefits.
Australian jury convicts Sydney business consultant over deals with suspected Chinese spies
A Sydney business consultant was convicted Friday of breaking Australia’s foreign interference laws by providing reports to two people he should have suspected were Chinese spies. Alexander Csergo, 5...
European businesses warn Brussels over push to end reliance on US tech
Companies argue that ‘tech sovereignty’ drive could hit profits and undermine continent’s competitiveness
How The HCA Healthcare (HCA) Narrative Is Shifting Around AI, Medicaid Support And Valuation
HCA Healthcare’s modeled fair value has been nudged higher from about US$541.52 to about US$543.05, signaling only a very modest adjustment to the price target range. Behind that small move, recent analyst commentary has focused on potential earnings support from Georgia’s Medicaid SDP approval and ongoing AI and efficiency efforts, while also flagging reimbursement and legislative risks that could limit how far targets stretch. As you read on, you will see how these moving pieces shape the...
NWSL Power Rankings: Gotham FC may be reigning champs, but they aren't No. 1 ahead of new season
With two new clubs in the fold, here is how all 16 teams rank heading into the opening weekend
This Healthcare REIT Just Faced a $15 Million Investor Exit Amid Lackluster Stock Returns
This healthcare REIT owns and leases medical facilities nationwide, generating income from long-term net leases with leading tenants.
Should the U.S. be in business of assassinating foreign leaders?
In the opening strike of their war on Iran, the US and Israel killed the Islamic Republic’s supreme leader, Ayatollah Ali Khamenei. It is an exceedingly rare instance of democracies killing a foreign head of state.It’s not the first time the United States has been involved in the killing of a foreign leader, but it’s something U.S. leaders and the American public have long wrestled with. NPR’s Ryan Lucas reports. For sponsor-free episodes of Consider This, sign up for Consider This+ via Apple Podcasts or at plus.npr.org. Email us at considerthis@npr.org.This episode was produced by Mallory Yu and Erika Ryan, with audio engineering by Jay Czys.It was edited by John Ketchum and Anna Yukhanov. Our executive producer is Sami Yenigun.
Breaking Down Meg Ryan’s Health Issues: Why Does She Limp?
The actress will be making high-profile appearance to honor Rob Reiner at the Oscars.
Colorado’s election audits are built on math, not politics
By Amanda Gonzalez You don’t build a secure election system overnight. You build it over years — layer by layer — reinforcing it with stronger safeguards, better technology and more transparency. In Colorado, one of those safeguards is a little-known but critically important process called a Risk-Limiting Audit (RLA). It’s math-driven, public and one of […]
A “ghost” great white shark just reignited a Mediterranean mystery
A rare encounter with a juvenile great white shark caught by fishermen in April 2023 has reignited scientific interest in the mysterious population of these apex predators in the Mediterranean Sea. By reviewing records spanning more than 160 years, researchers found that great whites still appear sporadically in Spanish Mediterranean waters, suggesting the population—though elusive and declining—has not vanished. The discovery of a young shark raises an intriguing possibility: these legendary predators may still be reproducing in the region.
Health systems use AI to break down language barriers in patient discharge notes
Translation systems are "trained to understand medication dosages, medical codes and other clinical terminology so the AI model works as it should," an Oracle engineer explained at HIMSS26.
Do You Dream of Opening a Resort on a Secluded Island? These 'Accidental Hoteliers' Did It
Mark and Gwenn Snider wanted to reimagine family travel.
Health IT leaders must adapt to the circuitous route of prescriptions
Hospital and health system CIOs should map current prescription workflows in detail and prioritize interoperability with clear governance frameworks, advises Joseph Kleiman, president of Rx tech company Buzz Health.
India-China reset? Relaxed rules allow Beijing to invest in India after about six years of friction
The Indian cabinet has approved changes to its foreign direct investment policy, allowing investments from "Land Bordering Countries."