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Alaska Democratic Senate candidate Mary Peltola and her family suffer minor injuries in car crash
Peltola required medical attention after the accident, which happened when another vehicle crashed into the one transporting Peltola and her family, the campaign said.
Erick All leaves Week 7 game early
Bengals TE Erick All ruled out after suffering a knee injury in Week 7
Alaska Democratic Senate candidate Mary Peltola and her family suffer minor injuries in car crash
Alaska’s Democratic Senate candidate Mary Peltola and her family suffered minor injuries Saturday in a car crash while driving to a campaign stop, her campaign said.
Scientists Develop a Clever New Way To Kill Cancer Cells From the Inside
Scientists have developed an experimental strategy that exploits a chemical byproduct of cancer cells to produce anticancer drugs directly inside them. Scientists in Japan have developed an experimental method that uses a chemical produced by cancer cells to manufacture anticancer drugs directly inside them. The approach relies on carbon monoxide, a toxic gas that certain
NFL Week 7 Sunday afternoon open thread
Join us at Buffalo Rumblings as we chat all things NFL Week 7 LIVE with like-minded folks in Bills Mafia
😱Fans back Carrick: How the United players left
Today, Manchester United suffered another crushing defeat, losing 0-3 to Bournemouth at Old Trafford. There was plenty of talk during the week about the rift between the players and Michael Carrick, p...
Kings' Veterans Praise Rookie Acuff After 33-Point Showing
The Sacramento Kings are yet to get a win, but Darius Acuff Jr. looks like the high-octane guard that the franchise so desperately needs. Coming off a 33-point outburst, how will Acuff play against the Memphis Grizzlies?
#ESMO26: Merck and Moderna's cancer vaccine data were 'a triumph of science.' And now, the work begins
Merck and Moderna’s intismeran cut melanoma recurrence risk 42% at ESMO; experts weigh other tumors, manufacturing and boosters.
ESMO: Roche touts ‘convincing’ phase 3 KRAS data after win over rivals
Roche has shed more light on its investigational KRAS G12C inhibitor's phase 3 victory over Amgen’s Lumakras and Bristol Myers Squibb’s Krazati. The open-label Krascendo 1 trial enrolled 338 people with previously treated KRAS G12C-mutated non-small cell lung cancer (NSCLC). Patients who had already received a KRAS G12C inhibitor or pan-KRAS/RAS inhibitor were excluded from the trial. Participants received either divarasib once daily, Lumakras once daily or Krazati twice daily. Roche announced back in July that divarasib had demonstrated statistically significant improvements in progression-free survival (PFS) and overall survival (OS), meeting the trial’s primary and key secondary endpoints. But the Swiss pharma had been holding back the detailed data until now. At the European Society for Medical Oncology (ESMO) Congress in Madrid, Roche revealed that median OS for the 167 patients who received divarasib was 17.7 months, compared to 12 months for the 171 patients who received Lumakras or Krazati. The benefit was similarly clear when it came to median PFS, which stood at 9.8 months versus 5.7 months, respectively. A total of 44% of patients receiving divarasib were alive without disease progression at one year, compared to 24% of the control group, according to Roche’s presentation. It was a similar story for the objective response rate, which came in at 58% for divarasib versus 32% for the control group, while median duration of response was 11.9 months versus 6.9 months. Stefan Frings, M.D., Ph.D., deputy chief medical officer at Roche Pharma, told Fierce that the data made for a “very comprehensive, strong package, which should be convincing to health authorities.” “It’s an important advance for patients with lung cancer,” Frings said in an interview at a Madrid hotel during the conference. “It's a second-line setting, and patients who receive divarasib benefit compared to the current first-generation KRAS G12C inhibitors by having far longer overall survival,” he continued. “They live longer. They have better progression-free survival, better response rates, and with a safety profile which is—if [anything]—even better,” he said. According to Roche, 4.8% of patients receiving divarasib discontinued treatment due to treatment-related adverse events, compared to 11.7% in the control group. Serious treatment-related adverse events were also less common with divarasib, at 7.8% versus 15.2%. Roche’s confidence in divarasib had been building even before this phase 3 success. The candidate had already shown better potency and selectivity than the incumbent KRAS G12C inhibitors Krazati and Lumakras in preclinical tests. After cross-trial comparisons suggested that the edge translated into better clinical outcomes, Roche axed a study comparing divarasib to the chemotherapy docetaxel and went toe-to-toe with Lumakras and Krazati. “We designed the drug on purpose with higher potency and better selectivity,” Frings explained. “So, based on preclinical models, we clearly knew it would be superior to the first generation.” “It’s honestly not so frequent that pharma companies go head-to-head,” he added. “But if you want to make a point, if you want to convince payers, prescribers and patients … then a head-to-head win is rather rewarding.” While Amgen and BMS reached the regulatory finish line first for KRAS G12C-mutated, locally advanced or metastatic NSCLC in 2021 and 2022, respectively, they have struggled to capitalize on their head start. Krazati brought in $55 million for BMS in the second quarter, while Lumakras delivered $111 million to Amgen. For its part, Roche is aiming for peak divarasib sales of 1 billion to 2 billion Swiss francs ($1.2 billion to $2.5 billion), according to Frings. The Big Pharma is currently recruiting patients into a phase 3 trial comparing divarasib plus Keytruda against Keytruda plus chemotherapy in previously untreated advanced or metastatic nonsquamous KRAS G12C-mutated NSCLC. Roche has previously suggested that sales in metastatic disease would account for most of the forecast. Frings was tight-lipped on the exact timeline for a regulatory filing but said the Swiss pharma is “certainly keen to get this to as many patients as possible around the world.” Roche has more RAS drugs coming up behind divarasib. The pharma has already launched phase 1 trials of a pan-RAS inhibitor called RG6505 and a KRAS G12D inhibitor dubbed RG6620 in solid tumors. Roche’s partner Chugai Pharmaceutical is also testing a pan-KRAS inhibitor called AUBE00. Roche has made a “deliberate effort” to test a range of RAS drugs, Frings said. “If you have many rare mutations and you are scrambling to find sufficient patients, a pan-RAS inhibitor makes a lot of sense,” he explained.
After Fighting in Gaza and Battling PTSD, Shahar Varon Seeks a Voice In Israel's Mental Health Future
Soldiers and others suffering from post-traumatic stress disorder […]
"I mean, stuff happens. It's a business. It's not in …
"I mean, stuff happens. It's a business. It's not in …
"I mean, stuff happens. It's a business. It's not in …
"I mean, stuff happens. It's a business. It's not in …
Hints About Why Sabres Missed Connor Hellebuyck
The fact that the Buffalo Sabres missed out on Connor Hellebuyck could linger painfully for a while if the goalie play in Western New York doesn’t improve in a hurry. It’ll hurt all the more because the reports over the summer indicated that for at least a time, the Sabres were the frontrunners to pull […] The post Hints About Why Sabres Missed Connor Hellebuyck appeared first on HEAVY.
Real Madrid rocked by Thibaut Courtois INJURY BLOW just hours before El Clasico showdown with Barcelona
Real Madrid have suffered a major setback ahead of their crucial Clasico showdown against Barcelona after goalkeeper Thibaut Courtois was ruled out through illness. His late withdrawal forces the club to rely on deputy Andriy Lunin for the vital Liga fixture at Camp Nou.
Former Minecraft lead, Xbox veteran and COO Helen Chiang "fired" for "policy violations"
A new report suggests that Helen Chiang, recently appointed as Xbox Chief Operations Officer, was terminated for "policy violations," although there's no word on exactly what.
Takeaways from Colorado's disastrous 57-24 loss to Oklahoma State
Oklahoma State fell to Colorado after an abysmal second-half collapse. Here are five takeaways from the Buffaloes' fifth straight loss.
Health Experts Reveal The 1 Thing They Wish Their Older Patients Would Do
Here are a few small ways to do yourself some major favors, from pros like cardiologists and nutritionists.
Are the Bills playing today? NFL Week 7 schedule, next game, AFC East standings
The Buffalo Bills and star QB Josh Allen are off to a terrific start to the 2026 NFL season. Here's what's on deck for the team in Week 7.
Opinion | Trump Should Stay Out of Brazilian Politics
The president seems not to understand that the global standing of the United States suffers when he plays into the stereotype of the ugly American.
What lymphatic drainage tools can and can’t do for your health
Influencers swear by lymphatic drainage to allegedly reduce puffiness, contour their faces and bodies, and boost overall health. We asked experts if you should just save your money.
Dana White Praises Merab Dvalishvili After UFC 333
UFC president Dana White praised bantamweight fighter Merab Dvalishvili following his fight against Petr Yan at UFC 333.In the trilogy championship bout between Yan and Dvalishvili, the two long-time rivals went the full 25 minutes and put on an absolute show as they went back and forth for five rounds before Yan ultimately edged out […] The post Dana White Praises Merab Dvalishvili After UFC 333 appeared first on HEAVY.
UFC 333 Highlights: Petr Yan vs. Merab Dvalishvili
Check out the highlights from the UFC 333 co-main event trilogy bout.
Cowboys Standout in Second Half in Win Over Colorado
Oklahoma State's defense stifled Deion Sanders’ Buffaloes while the offense exploded for 37 unanswered points, turning a halftime deficit into a dominant Homecoming rout at Boone Pickens Stadium.
Colorado's collapse brings more scrutiny on Deion Sanders
Colorado's 57-24 loss to Oklahoma State raises questions about Deion Sanders and his staff after a second-half collapse extended the losing streak.
Has Deion Sanders Started to Feel the Pressure in Colorado?
With a ballooning salary and a losing record, Coach Prime faces a harsh reality in Boulder as the Buffaloes struggle to snap a decades-long postseason drought.
The one thing Donna Mills refuses to do on her OnlyFans page
Donna Mills, 85, explains what she refuses to do on her OnlyFans page
Auburn's Georgia Momentum Disappears in Ugly Loss to LSU
Auburn football suffered a 38-17 loss to LSU at Jordan-Hare Stadium, falling to 4-3 after upsetting No. 1 Georgia. Sam Leavitt torched Auburn's defense for 387 passing yards, while Byrum Brown and the Tigers' offense struggled to find rhythm ahead of next week's matchup at Ole Miss.
LIVE! Watch UFC 333 Post-Fight Presser
With UFC 333 officially a wrap after an entertaining card earlier today (Sat., Oct. 24, 2026) LIVE on Paramount+ from inside Etihad Arena in Abu Dhabi, United Arab Emirates, fight fans can now check out the post-fight press conference video above for all the best reaction and official bonus winners. On a day that featured […]
Demichelis' Gamble Pays Off As Leipzig Crush Elversberg 4-0
After a tactical reshuffle, the Red Bulls maintained their flawless home record as Rômulo’s clinical double and Christoph Baumgartner’s emotional return ignited a dominant four-goal second-half blitz.
Netflix’s Leadership Shake Up…Explained
(Welcome to the “Most Important Story of the Week”, my bi-weekly strategy column analyzing the most important (but often not buzziest) news story of the last two weeks. I’m the Entertainment Strategy Guy, a former streaming executive who now analyzes business strategy in the entertainment industry. Please subscribe.) Well, I had a simple article planned for this week. Called “Whoa, I Missed It!”, I’d take a gander at a few important-but-under-the-radar stories I didn’t cover while I wrote about all things “Skydance. (Formerly known as “the saga of Netflix trying to buy Warner Bros., but not Discovery, then Paramount-Skydance bought all of Warner Bros. Discovery”.) Alas, that article will have to wait. Netflix made news. Ironically, my “Whoa, I Missed It!” article would have mostly been about “content” strategy decisions, which is also what today’s article is about. But instead of the entire industry, this article will only cover Netflix’s decision to upend their film and TV content teams. Just that! So that’s the full topic of the day. I’m going to tackle the issue in the opposite direction of the way “stuff” flows: uphill. We’ll start at film, then move onto TV, and then onto the CEOs themselves, and the strategy questions that still remain. But we start with the numbers driving this. Let’s dive in. Subscribe Most Important Story of the Week - Netflix Upends Their Corporate Hierarchy I’ve got a lot of thoughts, but we’ll start with the most common response to yesterday’s article. Let’s Talk Stock Price More than one person, responding to what I published two days ago, pointed out that, well, actually, the thing driving Netflix’s actions is this: In short, stock price! Even if Netflix isn’t obsessed with their own share price—they probably are, but, for the record, my strategic advice to every CEO is to absolutely ignore stock prices, which will, ironically, probably help the stock price long-term—most everyone thinks they are. By the way, I prefer market capitalization to stock prices, because it’s a more apples-to-apples way to compare companies: But there’s an even better way to look at it, and it kinda casts some doubt on the entire push here: price-to-earnings. I have a long list of articles that I wish I had written, and chief among them is an article titled, “Am I Still a Netflix ‘Bear’?” meaning someone who thinks Netflix’s stock is overvalued. As of last summer, Netflix had solved their biggest problem—which for me (circa 2019) was the lack of free cash flow—but their stock was CRAZY overvalued. That’s this chart here: Why did Netflix’s stock price increase to a price-to-earnings ratio of 50 last summer? What financial metric changed so quickly? Nothing. Given that, historically, mature entertainment companies average 10 to 20, with 16 being the average, that increase made little sense. Netflix’s stock swoon these last eight or so months wasn’t irrational; the stock price rise last year was. So if you want a really hot Netflix take, here it is: Netflix’s stock price has been going down because the financial industry recovered its senses, not because of any strategic mistake. Yes, that would imply that cleaning house may have been a mistake. That’s why the charts yesterday are so important, because they show that Netflix did have a strategic problem (a lack of hits) and that’s what they moved to address. (One could also argue the industry drastically overrated Netflix’s growth prospects, but that’s a financial industry problem, not a Netflix strategy problem per se. Some growth estimates are just crazy. *cough* AI *cough*) Now, the last time Netflix’s stock price crashed—circa 2022—it gave them an opening. I’d argue Netflix insiders knew they needed to expand post-COVID-19 crisis, adding advertising, cracking down on password sharing, and dabbling in sports. But if they had done that when their stock price was high, it would give folks a reason to second guess their strategy. (Arguably, last year, when Netflix pursued the Warner Bros. merger, it gave the industry a chance to review their business.) Instead, after the 2022 fall, they had the opening to make strategic changes. We may see Netflix pivot again following this latest slide. For example, the “binge versus weekly” conversation is alive and well again. Same for expanding into theaters even more. And adding both linear channels and streaming bundles. And maybe more either social, user-generated, vertical, or creator content. But the first shift came with who is making the content calls. A Message from Our Sponsor Last winter Pulp Fiction was on Netflix. For those same 90 days, it was also free, with ads, on Pluto TV and the Roku Channel. That is not a glitch, and it is not rare. The title has run on 20 different US streaming services since 2019, across 80 separate windows, and for more than 600 of those days it sat on a paid subscription service and a free ad-supported one at the same time. Almost nobody can see this, because when a title leaves a service, the record that it was ever there tends to leave with it. Reelgood keeps that record, dated to the day rather than the month: 4MM+ movie, show and episode titles across 300+ services globally, with timestamped arrivals, departures and moves across SVOD, AVOD, TVOD and vMVPD. Licensing teams price against every prior window. Rights teams check what a licensee actually delivered, and when. Pick a title you think you know: data.reelgood.com/title-availability Film - Dan Lin Want to know why I don’t opine on individual film or TV executives, especially new hires? Dan Lin. As I always caution, it’s really, really, really tough to predict which executives will succeed in new roles and which won’t. The successful head of co-production/finance partner, Rideback, Lin was considered for the head of DC Studios job before taking the job as the head of Netflix. By all accounts at the time, this was a smart hire. (That’s my read of the news coverage anyways.) But now that Netflix has fired Dan Lin, we got a slew of news stories about how he was doing a terrible job. In sports media, Bryan Curtis, new Substack writer/podcaster from The Ringer, calls this the “now you tell us” story, when you only hear the bad news after a star athlete leaves a sports team. In this case, now they tell us that Dan Lin was bad with talent after he got kicked out the door. So was Dan Lin a flop? It’s actually tough to say. While film moves faster than TV, even two years isn’t really enough time to evaluate a person’s output. The new head hasn’t really taken control. As Emily Horgan noted, it takes much longer than two years to produce animated films, so yeah, it’s definitely too early to judge in that domain. As for live-action films, I just published an article by Brandon Katz called “Netflix’s Summer of Bummer”, but I’d point out Netflix had a bad summer two years ago too. Arguably, their best summer came from KPop Demon Hunters last year and Happy Gilmore 2, the latter of which I saw credited to Lin. Then, the stories came out that Dan Lin clashed with talent, both Ben Affleck and Greta Gerwig, classic “now they tell us” factoids to explain his firing. This may have been true, but also should have been expected given that he was given the mandate to bring budgets back in check, especially after Rebel Moon. So if he made folks upset, well, that’s what he was hired to do! But also, he was described as “well-liked” at his hiring! In that case, I’m a bit sympathetic to Lin, since he may have been undercut by senior leadership, as often happens. Basically, a CEO hires a subordinate to be their “bad cop” and keep budgets in check, but then when talent complains, the CEO ends up undercutting them. That’s how I think you end up with a Narnia movie as expensive as any of the other flops, along with a film executive the town no longer likes. As a result, I think that Netflix is now executing a classic “hire the opposite” move by hiring Peter Rice. This phrase comes from my experience following football and basketball coaching decisions, where teams generally hire the opposite of who they just had. If you have an offense-minded head coach, hire the defensive guy. Or in college football, if you have a strong recruiter, then you pivot to an “X’s and Os” type of guy. Or in pro basketball, if you have a very analytically minded coach, you hire the player-friendly guy. I see that here. After dropping Scott Stuber—arguably a talent-friendly executive with lax budget control—Netflix hired the business guy to keep costs in check. Now Netflix is pivoting back to Peter Rice and presumably a more talent-friendly regime. (Disney, by the way, has done this twice: hiring business guys to succeed talent-friendly Bob Iger. It didn’t work out last time.) When it comes to Peter Rice…we’ll see! Maybe he works out, but maybe he doesn’t. I’d actually say the biggest problem is that Netflix still hasn’t solved its “IP Problem”, in that they don’t own much IP, so they just have a lower hit rate. The new executive won’t solve that. (Though buying Lionsgate would help.) Share “Content” - Bela Bajaria I almost published yesterday’s article after this column, but ended up flipping the order, because it told the story so well. So if you want the data for why Netflix is looking at TV to fix their problems, it’s in that article, this graph in particular: I know I just wrote that it’s often hard to judge executives, but Bajaria ran TV for six years and film for three and a half more. That’s more than enough to judge hit rates, and Netflix needs more hits. That’s the story. Since 2023, Netflix hasn’t had as many hit shows as it used to, and many of its previous power house TV shows have ended their runs (Stranger Things most of all). Also, many shows from 2020 to 2022 probably pre-dated Bajaria’s tenure. (That said, one thing may have been outside of Bajaria’s control, which I explain below.) Let’s lump some content strategy thoughts about Netflix and TV into one place: We’re just getting started with this issue, but the rest is for paid subscribers of the Entertainment Strategy Guy, so if you’d like to find out… Why I partially blame Squid Game for Netflix’s latest troubles… What is “the football trap”... Why it might not be the TV shows or films’ fault at all… What change I don’t think Netflix will make... How Bela Bajaria evolved Netflix’s TV strategy in smart ways… Whose departure likely submarined Bajaria’s final few years… One sneaky explanation for Netflix’s content struggles... And a whole lot more... ...please subscribe! We can only keep doing this great work with your support.
The real rebels of rock are those who ignore politics
Rockers once proved their "rebel" credentials by trashing hotel rooms, scuffling with bandmates or having their way with as many groupies as possible. Sometimes all three.
Unleashed Potential: Lantana sisters build growing dog treat business - Cross Timbers Gazette | Southern Denton County | Flower Mound
Alexis and Aubrey Gray are pretty proud of themselves. Over the past five years, the entrepreneurial-minded sisters, who are 15 and 12, respectively, have built a successful business selling homemade dog treats and snuffle mats to neighbors and even a handful of retailers. They’ve been invited to markets and trade shows, caught the attention of […]
Global Leading Robot Dog Dinosaur Manufacturer Hidinosaurs: Redefining Smart Entertainment at CAAPA
The location-based entertainment industry is entering a new era driven by Smart Entertainment, where interactive technology and immersive storytelling define
Where is Joe Rogan? UFC 333 broadcast absence explained
Paul Felder, a former MMA fighter, is filling in for Joe Rogan on the UFC’s commentary team during UFC 333 Saturday, Oct. 24 in Abu Dhabi.
This every-day action could be good for your health: ‘It’s like a mediating effect’
It is a coping strategy with some patients suffering depression or anxiety.
Missouri Doesn't Need More Marijuana Business Licenses, State Study Says, But Questions Remain About Ownership Concentration
“Ownership-based analyses would provide a more comprehensive assessment of market structure by evaluating concentration across common ownership groups.” By Rebecca Rivas, Missouri Independent Missouri regulators say the state doesn’t need to issue more licenses to grow, manufacture or sell marijuana because the legal cannabis market is meeting consumer demand. But the statewide study behind that conclusion couldn’t […]
AI giants are one big mistake away from catastrophe. They could learn a lot from the nuclear industry.
AI companies know they are being held hostage by each other, and that they need to take action to self-regulate before they suffer major reputational and legal consequences. There is a blueprint on how they can do it.
Arsenal Fear Bukayo Saka Injury Could Be Worse Than First Feared
Arsenal could be about to lose one of their most important players for a significant stretch of the season. Bukayo Saka will miss Saturday’s Premier League match against Everton after suffering a thigh injury against Bayern Munich, and the early signs have left Mikel Arteta concerned that the problem could be more serious than first […] The post Arsenal Fear Bukayo Saka Injury Could Be Worse Than First Feared appeared first on HEAVY.
The biggest political donors in Minnesota races this election season
Many of the ads now appearing on TV and social media are funded by a web of political committees and major donors whose connections are often difficult to trace.
Redes named RBHS Science student of the Semester
Red Bluff High School recently named fall semester science students through the first grading Oscar Redes a senior, with a GPA of 4.37 was recognized.
Live Life Fully: Stress, anxiety and the elections home stretch
The polls. The commercials. The group text that should come with a blood-pressure cuff.
Ausar Thompson Suffers Injury During Pistons Win over Heat
Detroit Pistons forward Ausar Thompson left Friday's game against the Miami Heat with an apparent lower-body injury, adding to concerns after Jalen Duren's exit.
UFC 333 final face-offs
During Friday's UFC 333 Ceremonial Weigh-In, the fighters faced off a final time before stepping in the octagon.
Health Brief: Making sense of Treasury’s biotech deal proposal
Pharma sees a potential catch in Washington’s latest effort to curb China’s biotech ambitions
Business owners react to new "no sit, no lie" designation, as street sign is posted
EVERETT — A pair of Everett business owners within the latest designated “no sit, no lie” buffer zone by the […]
U.S. labor secretary praises Kansas manufacturing industry in visit to Topeka business
U.S. Labor Secretary Keith Sonderling lauded U.S. job growth and Kansas’ manufacturing industry during a series of visits Friday, assuaging criticisms against the Trump administration for burdensome tariffs.
Littler through as Van Gerwen suffers early Euros exit
World champion Luke Littler makes it through to the second round of the European Championship with a win over William O'Connor but Michael van Gerwen is knocked out of the tournament at the first-round stage.
Improving breast cancer treatment; improving prostate cancer diagnosis; listen to your knee pain; plus other stories with Vanderbilt Health sources
WTVF News Channel 5’s “Morningline” program interviewed Denise Garcia, MD, Assistant Professor of Surgery, about new technology that helps surgeons identify cancer during surgery and improve breast cancer treatment. A Men’s Health story about PSA screening for prostate cancer quoted Kelvin Moses, MD, PhD, Professor of Urology. Men’s Health posted a story, “What Your Knee Pain is Trying to Tell You,” that quotes Charles Cox, MD, MPH, Associate Professor of Orthopaedic Surgery. William Schaffner, MD, Professor of Preventive Medicine, was quoted by several news outlets about public health issues, including: WSMV Channel 4 News (importance of flu shots); MedPage Today (mRNA flu shots); WTVF News Channel 5 (19 people sent to hospital after a sickness outbreak at Walmart facility in Lebanon); Prevention (West Nile virus); HuffPost (prevention pill for COVID); and Newsweek (measles cases continue to increase in the U.S.). Becker’s Hospital Review and Nashville Post covered the Vanderbilt Health News story from Rebecca Warren that Chief Communications Officer John Howser is retiring in March 2027, closing out a nearly 40-year career at Vanderbilt. A Healio story on research about OCT-A biomarkers and diabetic retinopathy quotes Vanderbilt University School of Medicine student Rachel Liu. WPLN Nashville Public Radio quoted Amanda Mixon, MD, MPH, Associate Professor of Medicine, in a story about adverse drug interactions.
Florida members pressure healthcare employer to return to the bargaining table
AFSCME Florida healthcare workers held a rally this month to demand their employer, UF Health Jacksonville, come back to the bargaining table.
Stand Up for Science Covers the Accidental Path to Prozac in the Latest “Traces Thursday” Installment
How an allergy pill reshaped the treatment of depression
Rodeo Cruelty Is Not Entertainment — Expedia Must Stop Selling Tickets!
Rodeos torture animals, inflicting terror, pain, injury, and sometimes death. Expedia must follow TripAdvisor: stop selling rodeo tickets.
NFL rescinds Buffalo Bills defender's one-game spitting suspension
Buffalo Bills defensive back Sam Franklin was suspended for spitting during a Week 6 game. A hearing officer overturned it, opting for a fine instead.
Capcom and Square Enix Suffer Online Attacks As Hackers Access Player Data
Japanese companies have been facing a growing number of security breaches in recent weeks
Cole Kmet will miss the rest of the season
Cole Kmet will be out for the Bears after suffering a knee injury.
Colorado Football Receives Near Failing Midseason Grade from CBS Sports
Recruiting failures, and locker room dysfunction threaten the "Prime Effect" as Deion Sanders struggles to steer the Buffaloes away from the Big 12 basement.
Woodruff makes Brewers' World Series roster as he returns from shoulder injury
Woodruff took the place of Chad Patrick on Milwaukee’s 13-man pitching staff as the Brewers and Tampa Bay Rays submitted their World Series rosters Friday before playing Game 1 in Milwaukee.
Brewers Place Brandon Woodruff On World Series Roster
The Milwaukee Brewers have placed Brandon Woodruff on the World Series roster
Business News: LVMH-Owned Zenith Is Restructuring In Major Reset As Brand Plans Job Cuts And Production Drop In Shift To High-End Market
Up to half of the employees at Le Locle manufacture could lose their jobs as the brand cuts models and production in restructuring after years of financial losses.
UF lecture to explore space through art and science on Nov. 16
Event slated at Harn Museum of Art.
This Chicago Mansion Is Hiding A World Of Magic Behind Its Historic Doors
Located near the Magnificent Mile, The Hand & The Eye offers three floors of immersive illusions, fine dining and secret passages.
Reviewing the Most Impactful Penn State Transfer Portal Departures
Penn State experienced a tumultuous 2026 offense. It was a carousel wash of players and coaches shuffling in and out of the Latsch Building, with 40 transfers entering and 47 transfers exiting. At 3-4 overall and 0-4 in Big Ten play, Penn State seems to be on the short end of the transfer portal transactions. …
Business activity expands, prices surge by most since 2022
Supplier delivery times lengthened the most since 2022, with S&P Global citing material and labor shortages as well as overloaded suppliers and shipping delays.
When computer science meets the alpaca immune system
After earning bachelor's and Ph.D. degrees in bioengineering with a focus on molecular biology, Will White, a postdoctoral scholar in the Department of Computer Science at Tufts, was pretty certain his ...
Arsenal fear Saka could be out for two months
Arsenal forward Bukayo Saka could be sidelined for up to eight weeks with the quadriceps injury he suffered against Bayern Munich.
AmEx lifts 2026 profit forecast, plans to cut 5% of workforce
By Manya Saini and Arasu Kannagi Basil Oct 23 (Reuters) - American Express raised its 2026 profit forecast above Wall Street expectations on Friday and announced plans to eliminate 5%
Dayton defense contractor Mile 2 names new ‘C’-level executives
Mile 2, a growing defense contractor in downtown Dayton, has appointed Matt Phaneuf as COO and Kyle Garza as its first CTO to enhance delivery of mission-focused solutions for the Department of Defense and national security clients, leveraging their combined 30 years of industry experience.
There’s a Reason That Netflix’s Ad Business Has Underwhelmed
Somewhat lost in the company’s slew of firings and engagement warnings over the past few weeks was the fact that Netflix is scaling back its ad forecast for 2026 from $3 billion to $2.7 billion. That’s despite the fact that: CTV is growing by 14-15% this year This year saw a monster upfront Netflix is the biggest streamer out there this side of YouTube, and was the platform that for years brands were supposedly dying to be a part of In other words, that’s an alarming pull-back from Netflix. A Wall Street analyst I spoke with last week was blunt, calling Netflix’s ad business “disappointing.” To me, a red flag on the ad front is that Netflix has never revealed how many ad-supported subscribers it has. Because if I know anything about how big companies work, if they have a positive number that makes them look really good - they tend to share it. (How many subs does go90 have right now? We’re not saying just yet. How are ads going on ChatGPT? Oh, a billion run rate - I see). Yes, to date Netflix has shared some fuzzy ad numbers, such as the idea that the company’s ad tier ‘reaches’ 250 million users globally.’ Here’s why that figure gives me pause: a)they lead with global, and b) they don’t explain how they are calculated. (Are they based on average people in each room? Surveys of some kind?). Regardless, some insiders say that Netflix’s ad tier is scaling nicely - others not so much. Either way, one of Netflix’s biggest challenge on the ad front appears to have been its starting point. Remember, when Netflix launched ads in 2022, it had 73 million subs in the US and Canada. That’s 73 million people who were used to Netflix with zero ads. And when the ad product rolled out, the company clearly was going after new users - a limited pool of potential subscribers by default. That focus seems to have changed over time, as Netflix has tried to convert longtime subscribers to the ad tier. Historically Netflix subscribers are very sticky. But is the company’s low churn a problem? Not necessarily, according to Antenna data. Rather, Netflix’s consumer loyalty is a bit of a double-edged sword. “Netflix is the one streamer which actually has seen substantial “trade downs” but has much lower ‘win backs,’ said Antenna founder Jonathan Carson (win-backs being people who were on the ad-free plan, cancelled, then rejoined on the ad plan). “Netflix has lower churn and so has less opportunity to win back old subs with a lower cost plan option.” This all might explain why Netflix has been so slow to roll out all of these table stakes targeting options until just this week. It likely didn’t have enough users to carve up into various targets. etc. However, what really hit Netflix’s ad business was Amazon’s move a few years ago to turn on advertising for Prime Video by default. Suddenly the market was awash in premium inventory, and Netflix was playing catch-up on multiple fronts. Thus, the streaming giant appears to still be figuring out if if wants lead in ‘programmatic TV,’ or premium ‘upfront’ TV sales. “The CTV market now sorts into three businesses, and Netflix is not the leader of any of them,” wrote analyst Jack Myers. Ouch. So how does Netflix ratchet up its ads business? Get the next NFL package You’re gonna have to wait until 2030 unless one of the bigger media companies like Skydance opts out, but the easiest (not cheapest) way for Netflix to become a huge TV ads contender is to get one of the regular NFL packages, ideally Sunday afternoons. That way it can sell ads to its whole U.S. subs base overnight. Go FAST This one is risky, because to program a compelling FAST channel, you’d likely have to take some older Netflix exclusive shows and make them available for free to non-subscribers. But FASTs, for better or worse, are ad-inventory machines. Go full UGC I’m not sure I see this happening. There is something already off about Netflix carrying podcasts and shows for creators. The experience sticks out in what is such a produced, and generally non-communal environment. But Netflix could open up its platform by allowing creators to upload videos without having to be approved by the service. But that opens a whole other can of worms (policing brand safety, copyright infringement, overall quality). Make a huge RMN Deal I was going to suggest something crazy, such as ‘instead of buying Warner Brothers, Netflix should buy Target. But the company doesn’t want to be in the brick and mortar business. Yet for Netflix’s ad business to compete in an Amazon world, it needs to be able to connect ad exposures to shopping. What if, instead of letting Amazon target Netflix viewers with its DSP, Netflix inked a deal with Target, or even took control of Roundel, and created its version of the Amazon full-funnel for brands? Price us out. I hope they don’t do this, but Netflix’s price increases - while significant - haven’t been enough to push long-term customers out of the ad-free tier. But if they made those prices so prohibitive, it could push large swaths of consumers to trade down. Then again, that could also dent engagement - as binging becomes much less appealing once you bring ads into the equation. Or, they could just launch a bunch of hit shows and maybe everyone will quickly forget all this angst. More from Amazon unBoxed A few weeks ago, I recorded two podcasts live at Amazon’s unBoxed event in San Francisco. I was able to go really deep with several brand partners about how Amazon’s various data and ad products work - particularly the under appreciated Amazon Marketing Cloud. First, I talked with Laura Abadias Velilla, of the Amazon specialty agency Amerge, along with Amazon’s own Charlotte Maines, Vice President, Devices Content & Advertising, about how the two partners helped a very specific printer company Epson launch into a brand new category - high end projectors. It’s a great example of how brands connect audience data across platforms to make budget deployment decisions. Next, I chatted with Monks VP Head of Digital Investment for North America Tom Burchill about how the agency actually brought in data from Linkedin to help target B2B customers across various Amazon properties for the brand Quicken. Check it out: Check these out, or just listen:
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How well have past GOTY winners sold?
We’re less than two months away from 2026’s The Game Awards, and what a year it’s been for fantastic games, including Resident Evil Requiem, Forza Horizon 6, Slay the Spire II, the Blood of Dawnwalker, and Control Resonant – just to name a few. So as we approach the end of the year, we thought we’d look back on our estimates for the GOTY winners of the past four years. In terms of revenue, Elden Ring (2022 winner), Baldur’s Gate 3 (2023), Astro Bot (2024), and Expedition 33 (2025) have generated a combined $3.8B via 73M copies sold: Let’s have a look, then. Elden Ring has generated $2B in revenue Elden Ring is a phenomenon in every sense. It’s sold a whopping 36.4M copies across Steam (50%), PS5 (35%), and Xbox (15% across console and PC). Want more free estimates and insights in your inbox twice a week? Subscribe below! Subscribe Elden Ring also just passed an astronomical milestone: $2B in revenue. While PlayStation and Xbox account for half of Elden Ring’s copies sold across these three platforms, they account for 57.5% of revenue. This – as ever – is due to regional pricing and the higher relative share of PC gamers in lower-priced markets. For example, around 17.4% of Elden Ring’s Steam copies sold were in China, where the game costs about 26% less than the price in the States. There’s an … interesting narrative going around these days that console gamers are only interested in ball-and-gun games and have the patience for little else. Well, Elden Ring’s impressive sales prove that is simply not true, and across all platforms. What’s more, over 9.8M people have played Elden Ring for over 100 hours, with nearly 3.5M people getting all of the achievements and trophies. For reference, 10.9% of Elden Ring’s PlayStation players have the platinum trophy, while 10.5% of players on Steam and 3.9% of Xbox players unlocked all the achievements. Git gud, Xbox players! Of the 1.5M people who played Elden Ring on PlayStation last month, 4% also played Dark Souls 3 last month, 4% played Bloodborne, and 3% played Sekiro. There’s those Soulsborne diehards for you. By many accounts, including my own, Elden Ring is one of the best games of all time. It’s an evergreen seller that will continue to be a cash cow for Bandai and FromSoftware for years to come. Want more free estimates and insights in your inbox twice a week? Subscribe below! Subscribe Elden Ring has sold another 2M copies across Steam, PlayStation, and Xbox this year, generating almost $110M. This means it’s outperforming many of this year’s high-profile releases. Even Elden Ring’s standalone run-based PvE spinoff, 2025’s Nightreign, has sold 7.8M copies and generated $282M in revenue. Baldur’s Gate 3 is another billion-dollar-plus banger Another cross-platform phenomenon is Baldur’s Gate 3, which has sold 23.2M copies and generated over $1.2B in revenue. About 18.7M of these copies (80.6%) are via Steam, 2.9M via PS5 (12.7%), and 1.6M (6.8%) via Xbox. Around 1.3M folks on Steam bought BG3 before it hit 1.0. The PlayStation version launched about a month after the PC 1.0 release, while the Xbox version came four months later due to technical issues around developing local co-op on the Series S. Want more free estimates and insights in your inbox twice a week? Subscribe below! Subscribe Across platforms, Baldur’s Gate 3’s monthly active users have never dropped below 2M, including 2.2M MAUs last month (68.5% on Steam, 21.9% on PS5, and 9.6% on Xbox). And it still regularly brings in 280K to 400K players every day: About 1% of BG3’s Steam player base has played for over 500 hours! That’s a little under 200K people. Astro Bot is also an evergreen seller, albeit a more niche, family one Astro Bot, 2024’s winner, has now sold 4.7M copies and generated $291M in revenue. The budget, including marketing, is almost certainly under $100M, given the small Japan-based core team and three-year dev timeline. You can really see why the tides are changing toward less expensive hubs. Astro Bot is the only first-party winner on this list, but follows other first-party winners of The Last of Us Part II (2020’s winner), God of War (2018), and Breath of the Wild (2017). Around 46.6% of Astro Bot’s copies sold have been physical, which is far higher than the typical game. This makes sense for a couple of reasons: There’s a large family audience for this one, and physical boxes are an item to wrap when giving Astro as a gift. Astro has collector value for the PlayStation core (this is nostalgia-fueled platformer celebrating PlayStation’s history) Want more free estimates and insights in your inbox twice a week? Subscribe below! Subscribe Astro is another one of those games that continues selling over time, regularly selling more than 100K a month. It’s sold around 1M more copies this year ($60M in revenue) and is a popular title with families. We can see this using the Alinea platform’s MAU crossover tool: Astro Bot’s top #2, #3, and #4 games by crossover in any given month this year are Minecraft, Fortnite, and Roblox – without fail. The #1 title every month, though, is Astro’s Playroom, a pack-in with all PS5 consoles. For every month this year, between 20% and 30% of Astro Bot players also played Astro’s Playroom that month. So the free pack-in is a noice funnel for converting players to a full paid product. Expedition 33 sells 8.7M despite Game Pass cannibalisation Finally, we have last year’s winner – Expedition 33. The turn-based-RPG banger has generated $366M via 8.7M copies sold, with 58.8% on Steam, 35.7% on PS5, and 5.5% on Xbox. Xbox’s share of copies sold is this low due to Expedition 33 launching on Game Pass, where 4.3M people across console and PC accessed the game. A little under 700K Xbox players used their subscription to play Expedition 33 this year. That said, the game’s 1.5-year Game Pass deal ended last week on October 16, and we’re already beginning to see a positive trend on Expedition 33’s copies sold via Xbox (but the jury’s still out!). There’s understandably a lot of French pride behind this one, as France is the game’s #3 market on both Steam and PlayStation. Vive la France! One thing that stood out to me is that the GOTY winners aren’t $300M Hollywood productions made in the US. They’re mostly mid-budget studios outside the traditional AAA cost centres. Lots to think about there. Also, good games sell well; who’d have thunk it!? And there’s a whole load of them this year, with GTA 6 still to come, too. GTA just made the cutoff point for the VGAs this year. What a coincidence! Loading... Cool links and other stuff Our physical games newsletter from Tuesday was picked up by GameSpot, Eurogamer, TweakTown, and a bunch of others. We’re offering a free trial of our platform for games companies. Send us a message here, or reply right here on Substack/email, and we’ll set you up. Next week, we’ve got some exciting news regarding the future of our newsletter, so stay tuned! The last word Reply to this email – or reach out here – if you have any feedback for the newsletter – or want to request a game for us to cover. Want to see why these companies (and many others) are subscribed to Alinea? Get a free platform trial! [Alinea Analytics boasts the most accurate PC and console estimates in the business. Game makers use our platform to understand their audience, keep an eye on the competition, monitor sales trends, and spot new opportunities. We equip game studios and financial institutions with accurate data and the confidence to make smarter, data-driven decisions. Want to talk about all things games market data? We’d love to chat!]
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AI as the next political divide
We have a guest post today from our friends at Focaldata, with whom we have done polling before. They have been doing a lot of work on attitudes towards AI and how this is affecting politics on both sides of the Atlantic. In this post, they explore exclusive new polling – with a whole set of fascinating charts on how voters’ views are developing and why. In particular, the authors explore why the debate is currently so much more polarised by party in the US than in the UK, to the benefit of the Democrats. Subscribe Focaldata HQ is located in Shoreditch, east London. To access the office from the Shoreditch High Street Overground station, you have to walk under the bridge at Braithwaite Street. We mention this not as a navigational aid, but because the posters above caught our eye over the summer. Since June, the area has been the centre of a fiercely contested debate around the construction of a data centre on the Truman Brewery estate on Brick Lane, less than 200 metres from our office. It was one of the first ‘US-style’ protest movements around AI data centres the country has seen, and may not be the last. These protests served as the catalyst for our forthcoming report, examining whether AI could become the next political divide on both sides of the Atlantic. We wanted to understand what was driving the emerging politics of AI and whether the dynamics at play in the US offer clues as to how the British debate will evolve. Over the last month, we polled 3,851 people across the UK and US about their views on AI. Our research found striking similarities between the two countries: for instance, both electorates are evenly split on their views towards AI development, with just over a third in favour (37% in each country), a similar number opposed, and the remainder somewhere in the middle or unsure. Statistically speaking, there is no difference in overall sentiment towards AI between the UK and US. Under the hood, demographic patterns also look largely the same in the two countries, with millennials, degree holders, full-time workers and those who describe themselves as financially comfortable more pro-AI than the rest of the country. Despite this convergence in overall attitudes, there is a striking divergence in how much of a politicised issue AI has become. In the US, attitudes are increasingly split by political affiliation and the issue has become the latest front in the seemingly interminable culture war, playing a role in the upcoming midterms. This stark political polarisation of AI has not happened in the UK – at least not yet. In what follows, we test several hypotheses for why the two countries are so far apart on a political basis. Understanding which hypothesis is correct will give us an indication of where the British dynamics go next.
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