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Health benefit costs to jump 8.2% in 2027, highest since 2003
Marsh survey finds GLP-1 drugs, AI billing, and No Surprises Act disputes are each adding a full percentage point to trend
Blue Ridge Health plans new medical facility in Hendersonville
WLOS News 13 provides local news, weather forecasts, traffic updates, notices of events and items of interest in the community, sports and entertainment programming for Asheville, NC and nearby towns and communities in Western North Carolina and the Upstate of South Carolina, including the counties of Buncombe, Henderson, Rutherford, Haywood, Polk, Transylvania, McDowell, Mitchell, Madison, Yancey, Jackson, Swain, Macon, Graham, Spartanburg, Greenville, Anderson, Union, Pickens, Oconee, Laurens, Greenwood, Abbeville and also Biltmore Forest, Woodfin, Leicester, Black Mountain, Montreat, Arden, Weaverville, Hendersonville, Etowah, Flat Rock, Mills River, Waynesville, Maggie Valley, Canton, Clyde, Franklin, Cullowhee, Sylva, Cherokee, Marion, Old Fort, Forest City, Lake Lure, Bat Cave, Spindale, Spruce Pine, Bakersville, Burnsville, Tryon, Columbus, Marshall, Mars Hill, Brevard, Bryson City, Cashiers, Greer, Landrum, Clemson, Gaffney, and Easley.
Survey: Biggest spike in health benefit costs over past two decades expected in 2027
A new survey from global strategist, Marsh, released this week, found that the average cost for health care benefits per employee are expected to rise 8.2% next year, more than doubling the rate of…
No. 18 Penn State vs. Marshall Preview & Prediction
It's been over eight months since Penn State football last played a game. In that time, the Nittany Lions have established almost an entirely new coaching staff, added 15 signees, seven walk-ons and a program-record 40 transfers, watched 74 players leave either via the transfer portal, the NFL or graduation, and even switched apparel partners …
Employer health costs are poised to see their biggest jump in over two decades
A Marsh survey of more than 1,800 employers found the expected increase would be the largest since 2003
Green Bay Packers: NFL insider suggests Marshawn Lloyd may be RB1 even if Josh Jacobs is cleared
The Green Bay Packers are not going to have Pro Bowl running back Josh Jacobs for the start of the season. While he is not injured, Jacobs has been placed on the commissioner’s exempt list following the news that criminal charges have been filed against him in relation to his arrest back in May for [...]
Rising costs of health benefits: Total cost per employee expected to rise 8.2% in 2027
Joseph Kra, Marsh senior partner and northeast health zone practice leader, joins 'Squawk Box' to discuss the rising costs of health benefits, impact of GLP-1s on health benefit costs, and more.
YouTube Gold: Appalachian State Shocks The World
The Big Ten has been a football powerhouse for more than a century, and the main driving forces of that dominance have almost always been Ohio State and Michigan. Michigan Stadium, generally known as the Big House, seats 107,601, but they can squeeze in 115,000 on a big day when the fire Marshall’s not looking. […]
WVU, Marshall leaders detail latest developments at universities, local communities during Business Summit
University, health, and city leaders covered a cornucopia of topics Wednesday.
WCU political expert explains Rep. Edwards' censure, breaks down overwhelming vote
WLOS News 13 provides local news, weather forecasts, traffic updates, notices of events and items of interest in the community, sports and entertainment programming for Asheville, NC and nearby towns and communities in Western North Carolina and the Upstate of South Carolina, including the counties of Buncombe, Henderson, Rutherford, Haywood, Polk, Transylvania, McDowell, Mitchell, Madison, Yancey, Jackson, Swain, Macon, Graham, Spartanburg, Greenville, Anderson, Union, Pickens, Oconee, Laurens, Greenwood, Abbeville and also Biltmore Forest, Woodfin, Leicester, Black Mountain, Montreat, Arden, Weaverville, Hendersonville, Etowah, Flat Rock, Mills River, Waynesville, Maggie Valley, Canton, Clyde, Franklin, Cullowhee, Sylva, Cherokee, Marion, Old Fort, Forest City, Lake Lure, Bat Cave, Spindale, Spruce Pine, Bakersville, Burnsville, Tryon, Columbus, Marshall, Mars Hill, Brevard, Bryson City, Cashiers, Greer, Landrum, Clemson, Gaffney, and Easley.
The Trump administration is burying science and health care in paperwork
This White House has become the paperwork administration, write Brandon Marshall and Abdullah Shihipar.
The Trump administration is burying science and health care in paperwork
This White House has become the paperwork administration, write Brandon Marshall and Abdullah Shihipar.
Marshall Health Network adds five pediatricians to its care team
HUNTINGTON, W.Va. – Marshall Health Network recently welcomed five pediatricians to its team of providers. Rita M. Ryan, M.D., professor and chair of pediatrics at the Marshall University Joan C. Edwards School of Medicine, is a board-certified neonatologist and nationally recognized neonatal lung specialist. She brings extensive experience as a clinician and pediatric leader, including previous service as pediatrician-in-chief at the Medical […]
Only Koby Howard Days Until Penn State Football
Penn State is less than a week away as the Lions will be at home in six days to take on Marshall. Wide receiver Koby Howard will be wearing No. 6 for Penn State this season. A year ago, Howard was getting buzz in camp about his play, but he didn’t really start seeing the […]
Ala. health system opens operations center with plans for up to 250 jobs
Huntsville Hospital Health System and Marshall Medical Centers opened a 32,000-square-foot operations hub in Arab to support scheduling, billing, customer service and other health care functions
24th Annual BioBlitz at Seacoast Science Center
Join Seacoast Science Center on Sunday, September 20, 2026 for the 24th BioBlitz, the non-profits annual community science event in Odiorne Point State Park. Families and nature enthusiasts team up with SSC naturalists and guest experts to explore the Park’s habitats to find and identify as many different species as possible in just one day! BioBlitz is a great way to get kids (and adults!) excited about science, learn about the park’s biodiversity, and discover how you can help protect our natural world.Like an extreme nature scavenger hunt, BioBlitz offers many opportunities for all ages to gain knowledge and hone skills in their favorite areas of nature! Habitat, plant, and animal explorations are scheduled throughout the day, allowing participants to choose among activities that interest them the most. With seven distinct natural habitats to survey, there’s something for everyone! Explorations include tide pools, mammals, seine netting, salt marsh, mushrooms, and more (see full schedule online, subject to change). Find all the details on the BioBlitz web page, and get your tickets to explore with SSC: https://www.seacoastsciencecenter.org/events-overview/bioblitz
Senator Marshall, Stormont Vail Health discuss rural healthcare transformations
Senator Roger Marshall met with leaders at Stormont Vail Health to discuss ways to improve rural healthcare.
Marshall Street Crash Under Investigation; Businesses Remain Closed Until Damage Repaired.
Glass litters Tres Ninos' floor on Friday. Right, the front logo from the truck is screwed into the plywood covering the front of the building. NORTH ADAMS, Mass....
Marshall only expensed Florida trips before hurricane damage, reports show
A review by The Star revealed that U.S. Sen. Roger Marshall stopped billing taxpayers for trips to his Florida shortly before it was hit by a hurricane.
Maryland Zoo's remaining male cheetah euthanized following health complications
WBFF Fox45 provides local news, weather forecasts, traffic updates, notices of events and items of interest in the community, sports and entertainment programming for Baltimore and nearby towns and communities in Maryland, including Annapolis, Crofton, Glen Burnie, Linthicum, Pasadena, Severn, Cockeysville, Dundalk, Essex, Parkville, Owings Mills, Towson, White Marsh, Woodlawn, Hampstead, Sykesville, Taneytown, Westminster, Elkton, Perryville, Pt. Deposit, Rising Sun, Aberdeen, Abingdon, Bel Air, Edgewood, Fallston, Havre De Grace, Columbia, Elkridge, Ellicott City, Fulton, and Ocean City.
Column: A sad ending for sports talk radio host Mike Mulligan — and some unsolicited advice for The Score
Sports talk radio WSCR-AM 670 fired Mike Mulligan and Marshall Harris without explanation. What we know — and what we hope to hear on a new Score.
As Seas Rise, Scientists Race to Save Coastal Marshes From Drowning
A majority of coastal wetlands are on track to shift inland or disappear in the coming decades without intervention. That will have major consequences.
Jordan Marshall Is Michigan’s Dark Horse Heisman Candidate
When talking about potential Heisman Trophy candidates entering the 2026 college football season, Michigan running back Jordan Marshall isn’t one of the first names that gets brought up. Maybe he should be. Marshall enters his junior season as Michigan’s clear No. 1 running back after a breakout 2025 campaign, and everything appears to be lining…
New medical office building at Three Rivers Health to replace 3 others damaged in tornado
WWMT-TV Newschannel 3 provides local news, weather forecasts, notices of events and entertainment programming for Kalamazoo, Grand Rapids, Battle Creek, South Haven, Paw Paw, Portage, Otsego, Texas Township, Oshtemo, Plainwell, Allegan, Holland, Saugatuck, Holland, Wayland, Kentwood, Middleville, Hastings, Marshall, Three Rivers, Sturgis, Constantine, Coldwater, Albion, Wyoming, Hudsonville, Allendale, Byron Center, Hudsonville, Grand Haven, Muskegon, Sparta, Rockford, Belding, Greenville, Ionia, Cedar Springs and their surrounding areas.
Bruce Springsteen biographer and music critic Dave Marsh dies at 76
Dave Marsh, a renowned music critic known for his influential books on Bruce Springsteen, has died at 76. Friend Jeffrey St. Clair says Marsh died Friday in Connecticut. Marsh had
Bruce Springsteen biographer and music critic Dave Marsh dies at 76
Dave Marsh, a renowned music critic known for his influential books on Bruce Springsteen, has died at 76. Friend Jeffrey St. Clair says Marsh died Friday in Connecticut. Marsh had
Philadelphia Phillies Announce Brandon Marsh News During Twins Series
The Philadelphia Phillies secured a dominant win in the Field of Dreams Game on Thursday night in their series opener against the Minnesota Twins. After a day off Friday, the Phillies are back in Minnesota for a matchup with the Twins featuring right-hander Jesus Luzardo for Philadelphia and left-hander Connor Prielipp. Ahead of the matchup, […] The post Philadelphia Phillies Announce Brandon Marsh News During Twins Series appeared first on HEAVY.
Connecting Science, Community, and Resilience: AMS Executive Director Amanda Staudt on WeatherGeeks
AMS Executive Director Amanda Staudt recently joined Marshall Shepherd on WeatherGeeks to discuss her path to AMS, the evolving role of the Earth system sciences, and the importance of connecting…
Jeff Lightner
Jeff Lightner has been appointed Chief Growth Officer for Marsh McLennan Agency’s Midwest Region, to help shape the region’s growth strategy across talent and growth capital, carrier economics and sales operations.
Philadelphia Phillies Announce Brandon Marsh Change Before Cardinals Series Finale
The Philadelphia Phillies have announced their lineup for the St. Louis Cardinals series finale at Busch Stadium. The post Philadelphia Phillies Announce Brandon Marsh Change Before Cardinals Series Finale appeared first on HEAVY.
Hendersonville hospital celebrates opening of Adolescent Behavioral Health Center
WLOS News 13 provides local news, weather forecasts, traffic updates, notices of events and items of interest in the community, sports and entertainment programming for Asheville, NC and nearby towns and communities in Western North Carolina and the Upstate of South Carolina, including the counties of Buncombe, Henderson, Rutherford, Haywood, Polk, Transylvania, McDowell, Mitchell, Madison, Yancey, Jackson, Swain, Macon, Graham, Spartanburg, Greenville, Anderson, Union, Pickens, Oconee, Laurens, Greenwood, Abbeville and also Biltmore Forest, Woodfin, Leicester, Black Mountain, Montreat, Arden, Weaverville, Hendersonville, Etowah, Flat Rock, Mills River, Waynesville, Maggie Valley, Canton, Clyde, Franklin, Cullowhee, Sylva, Cherokee, Marion, Old Fort, Forest City, Lake Lure, Bat Cave, Spindale, Spruce Pine, Bakersville, Burnsville, Tryon, Columbus, Marshall, Mars Hill, Brevard, Bryson City, Cashiers, Greer, Landrum, Clemson, Gaffney, and Easley.
Star Politics: Can Hamilton beat Marshall in Kansas? Here’s the latest on Senate race
We’re exploring whether the Rev. Adam Hamilton gives Kansas Democrats a rare chance to snap their 94-year U.S. Senate losing streak in 2026.
Inside Marshall Wace's rocky credit push
Marshall Wace has seen several big names depart its credit team since Dan Shatz took over in 2024.
Surgery center to transition services to Marshall Health Network
Three Gables Surgery says procedures will transition to Marshall Health Network - St. Mary’s Medical Center and Marshall Health Network - Cabell Huntington Hospital.
College of Health and Human Development names summer 2026 college marshal
Elise Mitchell, a nutritional sciences major, will be the college marshal for the Penn State College of Health and Human Development summer 2026 commencement ceremony.
HD 10 candidate has yearslong history with White nationalist secessionist group
Marshall Rawson appeared alongside League leaders at a conference the local Republican Party had publicly repudiated.
Community science project aims to warn beachgoers of 'greenhead' hotspots
A unique kind of beast emerges from the marshlands of the East Coast each July.
Conservative firebrand who went viral with anti-CCP ad survives key primary
Marsha Blackburn defeated John Rose and Monty Fritts in the Tennessee GOP primary, positioning her as the likely next governor of the state.
Drunk driver crashes into business
According to WFFD Assistant Fire Marshal Eddie Mawson, the driver was drunk.
Franklin & Marshall\'s new course blends science and beer
Faculty members and staff at Franklin & Marshall College didn’t just gather to drink beer during a tasting event Tuesday afternoon. They were also grading science.
F&M Brewing Science
Rob Jinks, professor of biology, who teaches the Brewing Science class at Franklin & Marshall College, dispenses a New England Indian Pale Ale into a pitcher inside Fair Trade Cafe
How interpreter Caden Zane Marshall translates a show in real time
Marshall, a Chicago-based ASL interpreter who has worked in Wisconsin, shares why it’s key to have more than one interpreter at a theater performance.
Phillies' Brandon Marsh: Getting break with lefty starting
Phillies' Brandon Marsh: Getting break with lefty starting
Naji Marshall to remain trade-eligible despite extension with Mavs
Naji Marshall to remain trade-eligible despite extension with Mavs
Bannock County Fair returns to Downey with new attractions, live entertainment
DOWNEY — It’s called “the best little fair in Idaho” for a reason, and everyone is invited to join in the fun. A longtime Marsh Valley tradition, the Bannock County Fair returns to Downey on Monday, bringing six days of livestock shows, rodeo action, live entertainment, family activities and several new attractions to the Bannock […]
From the lab to the marsh, Georgia Southern students lead summer science research
As summer heat settles across the region, students in the College of Science and Mathematics (COSM) at Georgia Southern University are completing research projects from the laboratory to the salt marsh.
Phillies news: Brandon Marsh, Andrew Painter, Tarik Skubal
C’mon trade deadline, happen already
Computer science and engineering major named College of Engineering marshal
Ranjani Suraj has been named the summer 2026 student marshal for the Penn State College of Engineering. Suraj will receive bachelor's and master's degrees in computer science and engineering through Penn State's Integrated Undergraduate-Graduate Program, along with a minor in mathematics, during the University's undergraduate commencement ceremony, which will be held at 9:30 a.m. on Saturday, Aug. 15 at the Bryce Jordan Center.
Munetsi focussing on promotion, not his future
Wolves midfielder Marshall Munetsi says he will stay at the club "as long as they want me to be here" and is not worrying about his future.
Crawley and Brook help Sunrisers beat Super Giants
Leeds Sunrisers end Manchester Super Giants' unbeaten start to the season after chasing down 182 thanks to half-centuries from Mitch Marsh and Zak Crawley while Harry Brook chips in with 42.
More than 700 cyclosporiasis cases reported in North Carolina: health officials
WLOS News 13 provides local news, weather forecasts, traffic updates, notices of events and items of interest in the community, sports and entertainment programming for Asheville, NC and nearby towns and communities in Western North Carolina and the Upstate of South Carolina, including the counties of Buncombe, Henderson, Rutherford, Haywood, Polk, Transylvania, McDowell, Mitchell, Madison, Yancey, Jackson, Swain, Macon, Graham, Spartanburg, Greenville, Anderson, Union, Pickens, Oconee, Laurens, Greenwood, Abbeville and also Biltmore Forest, Woodfin, Leicester, Black Mountain, Montreat, Arden, Weaverville, Hendersonville, Etowah, Flat Rock, Mills River, Waynesville, Maggie Valley, Canton, Clyde, Franklin, Cullowhee, Sylva, Cherokee, Marion, Old Fort, Forest City, Lake Lure, Bat Cave, Spindale, Spruce Pine, Bakersville, Burnsville, Tryon, Columbus, Marshall, Mars Hill, Brevard, Bryson City, Cashiers, Greer, Landrum, Clemson, Gaffney, and Easley.
NC Secretary of State visits Whiteville to meet with rural small business owners
North Carolina Secretary of State Elaine Marshall visited Whiteville to meet with small business owners and community leaders as part of her Rural Rise NC initiative, which aims to help small businesses succeed in rural areas.
Amendment 68: New Opportunity: D.8 Habitable Worlds Observatory Precursor Science Investigations
The Habitable Worlds Observatory (HWO) is a large-aperture ultraviolet/visible/near-infrared observatory concept recommended by the National Academies of
Provincetown Carnival names whale-saving group as grand marshal
Center for Coastal Studies will lead the Provincetown Carnival parade in honor of 50 years of research and conservation in Cape Cod Bay and beyond.
How a rural health merger brought more care closer to home
The combination of Sanford Health and Marshfield Clinic helps recruit physicians, improve retention and expand access to care in rural communities.
NC Secretary of State to visit Columbus County for small business roundtable
North Carolina Secretary of State Elaine F. Marshall is set to travel to Columbus County to meet with small business owners.
Science with Steve: Science behind dangers of deep frying a frozen turkey
KTAL NBC 6/KMSS FOX 33/KSHV 45 - Local news, Weather, Sports | Shreveport, Marshall, Texarkana
UMaine-led team selected for inaugural DOE Genesis Mission to advance AI in underground science
Beneath Maine’s salt marshes, an invisible transformation is constantly underway. Water moves through soil and rock. Chemicals react. Tiny microbes living underground help determine whether minerals dissolve or form, how fluids move and whether pollutants break down or spread. Existing computer models used to guide decisions about energy infrastructure and…
Marsh quarterly profit rises on strength in risk management business
Insurance brokerage Marsh reported a jump in second-quarter profit on Tuesday, as it benefited from robust demand for its risk management and consulting businesses.
Ernst Names Small Business of the Week, Taylor’s Maid-Rite
Read the release on Sen. Ernst's website HERE. Throughout this Congress, Chair Ernst plans to recognize a small business in every one of Iowa’s 99 counties. RED OAK, Iowa – U.S. Senator Joni Ernst (R-Iowa), Chair of the Senate Small Business Committee, today announced her Small Business of the Week: Taylor's Maid-Rite of Marshall County. Throughout the 119th Congress, Chair Ernst plans to recognize a small business in each of Iowa's 99 counties. "Taylor's Maid-Rite has truly maid their mark as a cornerstone of Marshalltown's business community," said Chair Ernst. "For nearly a century, this shop has served generations of Iowans with a signature burger made fresh every day. This 'Maid in Iowa' success story has proven that consistency, quality, and genuine customer care are the recipe for lasting success." Founded in the heart of Marshalltown, Taylor's Maid-Rite has remained a family-owned business for nearly a century and is now entering its fourth generation of Taylor family ownership. Best known for its signature Maid-Rite sandwich, the restaurant also serves classic American diner favorites, including malts, pies, fries, and sodas. Throughout its history, Taylor's Maid-Rite has remained committed to fresh ingredients, personalized service, and strong community involvement. Stay tuned as Chair Ernst continues to recognize outstanding Iowa small businesses with her Small Business of the Week award. ###
Heat stroke, exhaustion biggest RAGBRAI concerns for county public health
The National Weather Service is predicting that Marshall County’s temperature and heat index – 92 degrees with a heat index of 101 – will persist and possibly increase on Monday. The high temperatures felt across the state will greet RAGBRAI riders as they start the journey on Sunday in Onawa. Once they reach Marshalltown on […]
AP Entertainment SummaryBrief at 5:58 a.m. EDT
Social media influencers Andrew and Tristan Tate arrested in Miami, US Marshals Service tells AP
Only Cooper Cousins Until Penn State Football
We’re exactly 50 days away from Penn State kicking off its 2026 football season against Marshall, and today we’re honoring a person who is widely expected to help anchor the offensive line. After seeing playing time mainly on special teams as a freshman, Cooper Cousins saw action on the O-line as a sophomore last season, […]
Marshall Athletics Announces Partnership With Collegiate Sports Connect
Marshall Vice President and Director of Athletics Gerald J. Harrison announced a multi-year partnership with Collegiate Sports Connect on Tuesday.
Dr. Hillary Porter of Marshall Health Network named 2025 West Virginia Pediatrician of the Year
CHARLESTON, W.Va. – Hillary N. Porter, D.O., associate professor of pediatrics at the Marshall University Joan C. Edwards School of Medicine and board-certified pediatrician, psychologist and child and adolescent psychiatrist with Marshall Health Network, has been named the 2025 West Virginia Pediatrician of the Year by the West Virginia Chapter of the American Academy of Pediatrics in recognition of her dedication to children’s […]
UW Health agreement adds Beaver Dam medical center to its growing system
MADISON (WKOW) — UW Health and Marshfield Medical Center-Beaver Dam have officially reached an agreement to bring the medical center into the UW Health system of care, according to a
UW Health Finalizes Agreement To Acquire Marshfield Medical Center–Beaver Dam
BEAVER DAM — UW Health has finalized an agreement to bring Marshfield Medical Center–Beaver Dam into its health system, a move officials say will strengthen ... Read more
8 Cool New Gadgets to Keep on Your Radar
Catching you up on the past week’s most notable product releases.
Deana Carter To Headline Marshall County Fair Entertainment Lineup
MOUNDSVILLE — This year’s Marshall County Fair, slated July 19-25, will include a performance by country music star Deana Carter, known for hit songs like “Strawberry Wine.” Carter is scheduled to perform at 9 p.m. Saturday, July 25, on the main festival stage at the Marshall County Fairgrounds, 1433 12th St., Moundsville. Opening for Carter […]
Yahoo Sports launches college fantasy football leagues featuring Power Four players and Notre Dame
How about Texas quarterback Arch Manning paired with Ohio State receiver Jeremiah Smith on the same college football roster. While at it, add Michigan tailback Jordan Marshall, too.
Marshfield Clinic offering free sports physicals July 28
Marshfield Clinic is offering free sports physicals for Northwoods student-athletes 4:30-6:30 p.m. Tuesday, July 28, at Marshfield Clinic Woodruff Center, 1446 First Ave. (Hwy 47).
Marshall Football Has 12 Players Honored By Athlon Sports
Marshall Football had 12 players recognized by Athlon Sports as 2026 Preseason All-Sun Belt Conference selections, the magazine released recently. The Thunde...
Marshall hosts HSTA Fun with Science Institute for students
Around 75 students from across West Virginia are spending the week at Marshall University exploring careers in science, technology and health care through the
Former Cowboys DE Marshawn Kneeland diagnosed by researchers with stage 1 CTE
The former Cowboys defensive end died by suicide in November.
Wisconsin STEM shuttle program marks 20 years of taking science on the road
The STEM Shuttle, created by retired Wausau teacher Sharon Ryan, is marking its 20th year traveling to schools across Wisconsin. The program grew out of Dream Flight Wausau, a 1990 project Ryan developed while teaching at John Marshall Elementary School in the Wausau School District.
Why Kelly Reilly thinks Monica’s ‘Marshals’ death was a ‘missed opportunity’ in ‘Dutton Ranch’ season 1
Kelly Reilly is sharing why she thinks Monica’s death on fellow ‘Yellowstone’ spinoff ‘Marshals’ was a real ‘missed opportunity’ in season 1 of her and Cole Hauser’s ‘Dutton Ranch.’
Vehicle fire spreads to commercial business and apartments in Cambridge
The Office of the Maryland State Fire Marshal says a vehicle caught fire on July 3, then spread to the building it was parked under in Cambridge.
Five Phillies named All-Stars for 96th Midsummer Classic at CBP
Brandon Marsh, Bryce Harper, Kyle Schwarber, Cristopher Sánchez and Jhoan Duran will represent the Phillies in the 2026 All-Star Game.
Marshawn Lynch, Edgerrin James bring back Ice Bucket Challenge to support Chris Johnson after ALS diagnosis
Mission To Boost NASA’s Swift Launches From Marshall Islands
A mission to raise the orbit of NASA’s Swift observatory has reached orbit.
Marshall Health Network first in West Virginia to offer histotripsy treatment for liver tumors
HUNTINGTON, W.Va. – Marshall Health Network–Cabell Huntington Hospital (CHH) is the first hospital in West Virginia to treat liver tumors using the Edison® Histotripsy System, giving patients access to an advanced treatment that targets tumors with focused sound waves instead of surgery, chemotherapy or radiation. The Edison Histotripsy System uses image-guided sonic beam therapy to precisely target […]
Video shows masked thieves smashing glass, grabbing items during Bowie business break-in
WBFF Fox45 provides local news, weather forecasts, traffic updates, notices of events and items of interest in the community, sports and entertainment programming for Baltimore and nearby towns and communities in Maryland, including Annapolis, Crofton, Glen Burnie, Linthicum, Pasadena, Severn, Cockeysville, Dundalk, Essex, Parkville, Owings Mills, Towson, White Marsh, Woodlawn, Hampstead, Sykesville, Taneytown, Westminster, Elkton, Perryville, Pt. Deposit, Rising Sun, Aberdeen, Abingdon, Bel Air, Edgewood, Fallston, Havre De Grace, Columbia, Elkridge, Ellicott City, Fulton, and Ocean City.
Match for the Marsh with Barton Health
We’re back with another awesome opportunity to transform the south end of the Upper Truckee Marsh, this time with help from our friends at Barton Health! Now that the California Tahoe Conservancy has demolished the former Motel 6 building, restaurant, and parking lot from the Upper Truckee Marsh in South Lake Tahoe, planning is underway […]
‘Grateful and humbled’
MARSHALL — Two individuals who played important roles in building the Marshall baseball program into one of the state’s best were honored Sunday evening with induction into the Marshall Baseball Hall of Fame. Steve Fleck and Blaine Schnaible became the 20th and 21st members of this select group during a pre-game ceremony prior to the […]
Making Our Own Luck
We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.
David P. O'Brien
About five years ago, David P. O'Brien had a comfortable position at Marsh & McLennan Cos., where he held the top post at the financial giant's Louisville, Ky., office. Despite the lofty rank, Mr. O'Brien found himself longing to be at a smaller company that had to work a little harder to land business. That desire led him away from Kentucky five years ago and to Cleveland, where he serves as executive vice president at business insurance agency Oswald Cos. "I left Marsh before it was en vogue," he said, referring to layoffs and defections at Marsh over the course of this year that followed accusations of bid rigging at the big firm. Above all, Mr. O'Brien, 38, wanted to work at a company that relied on its inventiveness, rather than its name, for business. He said he has found that at Oswald. "It causes you to be more creative, to be more resourceful," Mr. O'Brien said. For instance, an Oswald client seeking to do business internationally might be directed to the network of offices abroad run by competitors such as Marsh and Aon Risk Services Inc. "We're going to use whatever access into the market that makes the most sense for our clients," he said. Of course, using such a strategy can be dangerous for Oswald if its client decides to further a business relationship with one of the firms Oswald recommended. "That's the obvious question and why it's nontraditional," he said. "I think if we're good, and if we're bringing value to the client, then there's no risk. I'm not threatened by it." Imaginative business solutions of that type made his career move to Oswald from Marsh worthwhile. "It's very much a challenge," he said. "It helps you keep your edge. I'm all for the competition." John Jacunski, currently vice president and corporate controller at York, Pa., paper company PH Gladfelter Co., met Mr. O'Brien four years ago when Mr. Jacunski was at WCI Steel Inc. in Warren. So impressed was he with Mr. O'Brien's work for WCI that Mr. Jacunski has retained the Oswald executive at PH Gladfelter. "He's a young guy for the position he has, but he's done a great job for us," Mr. Jacunski said. Among his roles at Oswald, Mr. O'Brien leads the firm's client retention efforts and also serves as director of its property and casualty group. "You don't have the same human resources," he said of the job jump to Oswald. "You don't have, obviously, the safety net a big company has." But sometimes, it can be difficult to ascertain individual contributions when working at a big company. "I wanted to be able to see the end results of my work and my efforts," Mr. O'Brien said.
Every Marshall player drafted by the Golden State Warriors
Let's take a look at every player who has been drafted by the Warriors out of Marshall.
MARCO Mobile Medicine Brings Care Closer to Home
For many families across Appalachia, a doctor’s appointment can mean taking time off work, arranging transportation, traveling winding mountain roads and spending hours on the road for a visit. It’s a challenge familiar to generations of West Virginians, particularly those living in rural communities where access to specialty care can be limited. Today, Marshall Health Network is helping change […]
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