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Commentary: Night shifts are deadly, not just inconvenient
During his 26 years as a night-shift nurse, Ed Collum watched colleagues nod off mid-conversation, battle chronic illnesses and, too often, die young from cancer, stroke or suicide. Collum puts
Australian forward continues to lead Golden State's summer league team
With Yaxel Lendeborg and Will Richard sidelined, Lachlan Olbrich tallied 21 points off the bench for the Golden State Warriors against the Miami Heat.
Darryn Peterson, Cam Boozer deliver in head-to-head NBA Summer League game
Kansas City lays a Royal beating on Phillies' All-Star Cristopher Sanchez
Cristopher Sanchez’ second-to-last audition to win the starting assignment for the National League in the All-Star Game did not go well on Monday.
Bucks' Brayden Burries: Summer League status unclear
Bucks' Brayden Burries: Summer League status unclear
Pascagoula mayor highlights development, flooding and youth sports
Pascagoula Mayor Jay Willis spoke last week at the Mississippi Municipal League Conference.
'I know Toure will be really successful'
Bazoumana Toure's positivity translates on to the field. The rapid winger certainly tried to make things happen at Hoffenheim, who narrowly missed out on qualifying for the Champions League last season. Of the forwards playing in the Bundesliga in 2025-26, Toure ranked first for successful crosses (39), joint-second for assists (nine), joint-third for dribbles completed (48) and fourth for chances created (45) and big chances created (11).
Southend sign defender Daley-Campbell
Southend United sign wing-back Vontae Daley-Campbell on a one-year deal following his release from League Two side Chesterfield.
Gossip: Hull target Milinkovic-Savic
Hull City want to sign Napoli and Serbia goalkeeper Vanja Milinkovic-Savic, 29, as they prepare for their Premier League return. (Corriere dello Sport - in Italian)
Kings F Nique Clifford Talks First Summer League Win
After burying a clutch go-ahead triple, the sophomore forward discusses his growth as a defensive anchor and his commitment to sparking a winning culture for Sacramento’s fans.
Jaguars’ QB Lawrence Outperformed His Salary Last Season
An MVP finalist campaign and elite efficiency metrics prove Jacksonville’s $275 million investment is paying off as the star signal-caller climbs into the league’s upper echelon of quarterbacks.
Eliezer Alfonzo has emotional day as Dodgers lose to Padres
Eliezer Alfonzo goes 0 for 2 in his major league debut, but there were more important things for the Dodgers catcher to think about.
Summer League Goals For Bulls Rookie Dailyn Swain
Swain has a higher ceiling than your usual 15th overall pick. Here's what we would like to see from Swain during his time in the 2026 NBA Summer League.
Sanchez scores twice and Courage top Reign 3-1
Sanchez moved past Kansas City's Temwa Chawinga with nine goals this season in the National Women's Soccer League.
Detroit Tigers Land Three American League All-Stars
Dillon Dingler, Kevin McGonigle and Riley Greene have been selected to represent the Detroit Tigers in the 2026 MLB All-Star Game.
Everton set to sign Tyrique George from Chelsea
The two Premier League clubs have agreed a deal over the 20-year-old winger
Reds’ Hunter Greene gives up a career-high-tying 8 runs in 2026 debut
It was Greene's first start since his three-inning start in a loss to the Dodgers in Game 1 of the 2025 National League wild-card series.
Carson Cooper Turns Heads with Outstanding NBA Summer League Debut
The former Spartan standout stole the spotlight in Memphis, flashing explosive athleticism and a surprising perimeter game to prove his versatile skill set belongs on the professional stage.
Sky Sports: Ipswich Set To Rival Fellow Promoted Side For Ligue 1 Star
Ipswich Town Enter Emersonn Race as Premier League Newcomers Move Against Hull CityIpswich Town have moved for Emersonn, and that tells you two things straight away. First, they are not approaching th...
Phillies bring all the fireworks to Royals’ fourth straight loss
The Royals fell to the Phillies 6-1 after Michael Wacha allowed four runs on three homers in six innings. This was Wacha’s first start after being named a 2026 American League All-Star. While it was among his worst starts of the season, it wasn’t a terrible start overall. He even struck out 7! But the […]
Randy Arozarena Named to 2026 American League All-Star Team
Randy Arozarena to represent Mariners in 2026 MLB All-Star Game
I took my 3 kids to a Mets Sunday family game. It's a core memory.
Watching my three children experience their first Major League Baseball game reminded me why family traditions are worth starting.
Former NL MVP will continue his career, signs with Braves
The Atlanta Braves have made a veteran addition as they look to stay atop the National League playoff race, signing former National League MVP Andrew McCutchen to bolster their organizational outfield depth. McCutchen, who began the season with the Texas…
NASCAR, New CEO Travel To Washington D.C. To Promote League
NASCAR and its new CEO Steve O’Donnell made a pit stop in Washington D.C. to amplify the impact of motorsports.
Cavalli and Contreras get 7-game bans after Nationals-Red Sox fight
Washington Nationals pitcher Cade Cavalli and Boston Red Sox first baseman Willson Contreras were each issued seven-game suspensions by Major League Baseball for their role in a benches-clearing fight between the two teams.
Suicide Squad development felt ‘like I wasn’t making games anymore,’ says director
Suicide Squad: Kill the Justice League director Axel Rydby shares his experience of working on the doomed live-service.
Roma, Basel reach agreement over Calafiori’s resale clause
Riccardo Calafiori is one of the players who emerged from Roma’s youth system and has managed to establish himself on the big stage. The former Giallorossi defender won the Premier League with Arsen...
Dodgers overcome Roki Sasaki's poor performance to rout Padres
Roki Sasaki gives up six runs in only three innings, but the Dodgers offense comes through by scoring 12 straight runs against the beleaguered Padres.
Cubs Minor League Wrap: Smokies shut out Columbus, 1-0
Iowa, Knoxville and Myrtle Beach all win. South Bend gets walloped.
Donald Trump's Freedom 250 celebration suffers setback as falling panel nearly crushes dancers
Donald Trump's beleaguered Freedom 250 celebration suffered another potentially disastrous setback on Thursday, when a large panel on the White House main stage fell, nearly crushing a group of dancers.
Malik Willis Has 6 Career Starts and CBS Sports Just Ranked Him Among the NFL's Most Intriguing QBs
The NFL is a pass-heavy league, and teams rely on aerial attacks and high-scoring offenses not just to win games, but to contend for a Super Bowl championship. "After rejuvenating his career in Green Bay, Willis will get his first legitimate chance to be an NFL starting quarterback," DeArdo wrote. "It'll be a challenge, though, as Willis is joining a Dolphins team that is starting anew."
NFL QB rankings: Arizona Cardinals QB Jacoby Brissett near bottom
Even with career numbers last season, Jacoby Brissett is one of the lowest-ranked QBs in the league, per PFF.
Rangers bolster minor-league depth by signing Cholowski, Gawdin
With Wednesday’s flurry of NHL moves behind them, the New York Rangers added some help for their the American Hockey […]
Cavs announce 2026 NBA Summer League roster
Nae’Qwan Tomlin will be joining the group heading to Vegas.
IDP Rookie Profile: Anthony Hill Jr. in Redraft Leagues
Anthony Hill Jr. lands in Tennessee with a starting role and enough downhill ability to become a useful rookie IDP option.
IDP Rookie Profile: Jacob Rodriguez in Redraft Leagues
Jacob Rodriguez enters a crowded Dolphins linebacker room, limiting his redraft value despite an impressive college résumé.
Former Arkansas basketball players preparing for NBA Summer League
At the time of writing, eight players who finished their careers with the Arkansas men’s basketball team have been announced on Summer League rosters.
Premier Lacrosse League raises $100 million as sport gears up for ‘biggest moment’ in its history
Another big valuation moment for an up-and-coming sports league.
ESPN expert thinks 2026 could be the Houston Texans' year
Solak believes the Houston Texans already have the league's best defense and will return nine starters on that side of the ball
How Paul Rabil is growing the business of lacrosse
Premier Lacrosse League Co-Founder Paul Rabil joins Yahoo Finance Executive Editor Brian Sozzi on Opening Bid to discuss the business of lacrosse, the sport's rising stars, and how the league plans to lower the cost of youth lacrosse.
City Hall visit, packed entertainment slate highlight 2026 HBCU Swingman Classic schedule
Major League Baseball today announced the pregame and philanthropic details for the 2026 HBCU Swingman Classic presented by USA Baseball, highlighted by a team visit to City Hall, Philadelphia Mayor Cherelle L. Parker’s first pitch, uniform patches honoring HBCU legend Roger Cador and pregame entertainment by Grammy-Award winner Durand Bernarr
Minor League Update: Rookie Leagues
Whenever I give updates on minor league stats, I’m always conflicted about how many players to include. Some of it is time management-related. Obviously, if I cover every conceivable player, it will take me time I sometimes don’t have. But I also am not particularly interested in writing 5,000 words for one of these either. […]
Liverpool sporting director Richard Hughes expected to join Simon Francis at Al Hilal
Francis, who replaced Hughes as Bournemouth’s technical director in 2024, is leading the Saudi Pro League club's transfer activity.
Tourists down ‘Burgers, 10-8, for second straight night
ASHEVILLE, N.C. — Six straight wins. Sole possession of first place in the South Atlantic League Southern Division. And a dominant pitching performance. Wednesday night had everything, and the Asheville Tourists came out on the right side of all of it, beating the Hub City Spartanburgers 10-8 behind a gem from Yeriel Santos and big nights […]
Lakers' summer league roster has been finalized
The Lakers have released their official 2026 summer league roster.
Climate scientist who “proved” humanity is warming Earth says government report got it wrong
A pioneering climate scientist is challenging a U.S. government report that cited his research while reaching what he says is the exact opposite conclusion. Benjamin Santer and his colleagues say decades of satellite data clearly reveal the atmospheric “fingerprint” of human-caused climate change. Their new peer-reviewed analysis argues the report contains major scientific errors and should not be relied upon in climate policy decisions.
Red Wings Sign Depth Defenseman
The post Red Wings Sign Depth Defenseman appeared first on Detroit Hockey Now. The opening of the NHL’s 2026 Free Agency period has seen the league trying to round out their rosters with […] The post Red Wings Sign Depth Defenseman appeared first on Detroit Hockey Now.
ESPN reportedly favorite to renew TGL media rights
TGL, the tech-infused simulator golf league co-founded by Tiger Woods and Rory McIlroy’s TMRW Sports, is in the market for a new media rights deal after having completed its second season earlier this year. The league spent its first two seasons on the ESPN family of networks, posting strong and stable viewership during a portion…
MLB Players Propose Limiting Optional Assignments To Minor Leagues, More
MLB players proposed that optional assignments to the minor leagues be cut from a maximum of five per season to three.
Bills’ Josh Allen continues dominating “best current NFL QB” debates
In a league full of elite talent, the better question is how much being the best really matters.
House Dem urges transparency by public officials after GOP colleague reveals reason for extended absence
Democratic Rep. Ritchie Torres urged transparency from officials after House Republican Tom Kean revealed the previously undisclosed reason for an extended congressional absence.
The new Pac-12 Conference officially launches with the addition of seven full-time members
July 1, 2026 — Today, seven new full-time member institutions officially join the Pac-12 Conference, including Boise State, Colorado State, Fresno State, Gonzaga, San Diego State, Texas State and Utah State. With the additions, the new Pac-12 features nine full-time members and is set to compete in its first season with the 2026-27 campaign. The league also officially welcomed 12 new affiliate members today across five Olympic sports, including baseball (Dallas Baptist), men’s soccer (Cal Baptist, Cal Poly, UC Riverside, UC San Diego), women’s gymnastics (Southern Utah), women’s swimming (Cal Baptist) and wrestling (Air Force, Northern Colorado, North Dakota State, Northern Illinois, South Dakota State). In addition to official member admissions and the launch of the new Pac-12, and amid celebrations across new member communities, the league also made a series of other announcements related to its basketball tournaments, its official sports sponsorship and championships and a special edition content series in promotion of its first football season.
A New Mountain West Era Begins
LAS VEGAS - Entering its 28th year, the Mountain West Conference officially begins a new era, marking a meaningful step in the league's continued growth and long-term strategic vision while maintaining its commitment to competitive excellence.
Cleveland Guardians’ Rookie Kahlil Watson Flashing Major League Tools
Cleveland Guardians rookie outfielder Kahlil Watson has shown power, speed, a good hit tool, and solid defense after his graduation to the major league club
5 takeaways from Colorado’s shocker of a 2026 primary election
Voters in Colorado’s Democratic primary on Tuesday night mostly let their elected officials know that they’re fed up with the party’s Washington politicians and ready to back the most aggressive fighters they can find. At the same time, the voters who cast ballots in the Republican primary mostly embraced the GOP’s establishment, throwing the beleaguered […]
How Elite Sports Coaches Make High-Pressure Decisions
Drawing on interviews with 11 elite coaches across major U.S., European, Australian, and New Zealand professional sports leagues, the authors show that high-pressure decisions aren’t a single “formula” but a set of practices that unfold before, during, and after pivotal moments—and translate directly to business leadership. Top coaches combine disciplined preparation with emotional control and social awareness during crunch time and accountability and continual system improvement after the fact.
Magic find out group pairings for upcoming NBA Cup
The Magic on Tuesday night drew a compelling group for Group Play of the NBA Cup, the league’s fourth-ever in-season tournament. Orlando was placed in East Group A alongside Detroit, Toronto, Milwaukee and Brooklyn. The tournament — which will consist of two stages including Group Play and the Knockout Rounds — starts Oct. 30 and will end with the title game (Dec. 11) at Hinkle Fieldhouse ...
Yankees’ Nightmare Week Should Worry New York Fans
The New York Yankees were looking like the best team in the American League by a wide margin this time last week. However, since all of the optimism, even with Aaron Judge and others injured, things have collapsed.
Premier Lacrosse League lands $100 million to chase Olympic moment
The funding comes at a crucial period of preparation for PLL, as it looks to capitalize on lacrosse being a part of the 2028 Summer Olympics.
Cricket club suffers 'vandalism' for seventh time
A cricket club says it has been forced to pull out of its league after its pitch is ploughed up.
Not many ‘Iron Men’ are left in Major League Baseball
Pete Alonso played his 500th consecutive game this week, although if he wanted that to seem impressive to local fans, he probably picked the wrong city to play in. Alonso, of course, joined the Baltimore Orioles this past offseason. Their franchise record for consecutive games is also the big league record of 2,632 by true […]
Arsenal part ways with Tom Allen, head of sports science and performance, Sam Wilson also set to leave
Allen's exit is the latest following the club ending their 22-year wait for a league title.
Trafalgar Entertainment acquires Nicholas Hytner’s Bridge theatre
London Theatre Company founded in 2017 by Hytner and former National Theatre colleague Nick Starr has been sold to company that owns 20-plus venues in UK and abroad
Ahead of the MLB trade deadline, here’s where the Guardians stand
The Guardians are among the best teams in a weak American League. This is the time for them to capitalize on their situation.
Ex-boss Foyle returns to Port Vale as chief scout
Former Port Vale player and manager Martin Foyle returns to the League Two club as its chief scout.
🎧 When belief returned: Episode five of new Coventry documentary
The relegation from League One to the bottom tier of English football starts episode five of Back Where We Belong. Under Mark Robins, Coventry City found their identity and stability on the pitch, with fans finding joy in small and shared moments. With Wasps still owning the Ricoh Arena, the Sky Blues were forced to ground-share with Birmingham City at St Andrew's.
White Sox Minor League Update: June 28, 2026
The Barons get the W and snap a losing streak thanks to a four-hit, five-RBI day from Caleb Bonemer
Reports: Diomande agrees PSG move from Leipzig
Ivory Coast forward Yan Diomande has decided to leave RB Leipzig for Paris Saint-Germain, according to media reports. Broadcasters Sky and RMC, as well as transfer specialist Fabrizio Romano, reported on Sunday that the 19-year-old has agreed a five-year contract with the French Champions League winners.
Khalid Robinson takes next step as Warriors' head coach for NBA Summer League
As he enters his 11th season with the Warriors, Khalid Robinson is about to step into a new role as Golden State's NBA Summer League head coach
🚨 BREAKING: Robert Lewandowski agrees multi-year deal with Chicago Fire
Major League Soccer looks set to add another iconic veteran presence to its ranks this summer, with Polish legend Robert Lewandowski reportedly primed for a move to Chicago Fire.Per The Athletic, the ...
Crusaders placed under transfer embargo by IFA
Crusaders have been placed under a transfer embargo by the Irish Football Association [IFA] after a breach of the Northern Ireland Football League [NIFL] rules and regulations.
Padres outmatched by Dodgers with nine run inning
SAN DIEGO - Just when things started to look like the San Diego Padres found a resurgence after winning four in-a-row against two of the best teams in league, they run into a mack truck-like force called the Los Angeles Dodgers.
Srikanth reaches US Open final; India vs England in hockey Pro League; final day of Inter-State Athletics: Indian Sports LIVE, June 28
Here are all the updates from Indian sports on June 28, 2026.
Cubs Minor League Wrap: Jaxon Wiggins rehabs with South Bend
Knoxville and South Bend both win, proving again the class of the Cubs system are the middle two teams.
Oxford bring in former Hearts defender Kent
League One side Oxford United sign former Hearts defender Frankie Kent on a free transfer.
Tony Goldwyn recalls Hollywood 'people that were mean' changing their attitude toward him after this hit film
Tony Goldwyn said that Hollywood colleagues treated him as if he 'had the plague' when he was an unemployed actor, and those same 'mean' people changed their tune after this hit movie.
Colby Parkinson is extremely valuable to the Rams offense
Analysts around the league are clamoring for him, but they’re almost certainly not going to pry him away from L.A.
Arsenal hold talks with Strasbourg technical director Pascal de Maesschalck
Arsenal have held talks with the technical director of RC Strasbourg Alsace, Pascal de Maesschalck, according to a report from The Athletic.The Premier League champions are in the process of finding ...
Sabres select defenseman Daxon Rudolph in first round of NHL draft
Rudolph played in 68 games with the Prince Albert Raiders of the Western Hockey League last season, scoring 78 points.
The mediocre American League will define this year's MLB trade deadline
Phase 2 of restoration project underway at West Herr Performing Arts Center
Members of the Rochester Broadway Theatre League say this next phase of work includes expanding the theatre's Rothschild Lounge back to its original size.
Two Yankees Pitching Prospects ‘Turning Heads’ in Minors This Year
The old saying is you can never have enough pitching, which the New York Yankees have apparently taken to heart. The Yankees have a stockpile of potential starting-pitching arms in the minor leagues, including Elmer Rodriguez, and two “head turning” prospects, Ben Hess and Chase Hampton. The Yankees lead the majors in team ERA (3.30) […] The post Two Yankees Pitching Prospects ‘Turning Heads’ in Minors This Year appeared first on HEAVY.
Big Ten women’s sports are having a moment. What is the league doing to capitalize?
In the two years since Caitlin Clark left for the WNBA, the Big Ten has worked to keep its momentum.
Is Mega Skarmory good for Pokémon GO Raids?
Super Mega Skarmory Raid Day brings one of the new Legends: Z-A Mega Evolutions to Pokémon GO, and gives the undeniably cool Skarmory a new lease of life in the Raids meta. A popular / type from Gen 2, Skarmory has been a staple in the Little and Great League formats, but has never made […]
Real Madrid’s summer spending spree creates unexpected Champions League problem
Real Madrid have been one of the busiest clubs in the transfer market, but their impressive recruitment spree may have created a technical issue.Notably, Jose Mourinho has already welcomed four new si...
It's Xbox's turn (again), as console prices keep going up
Microsoft announced a price hike for the Xbox Series consoles today, the third in little over a year. Effective August 1, the Xbox Series S, which launched in 2020 for $300, will cost $500 in the U.S. The Xbox Series X, which launched in 2020 at $500, will go for $800. This follows a round of PlayStation 5 price increases from Sony this spring, and a slow-motion increase for Nintendo’s Switch 2, which will kick in in the U.S. in September. (Mind you, there were also eight video game industry price hikes in six months of 2025). The chart up top shows the sudden ascent of console prices over the past year, a sudden surge in an already unusual hardware generation. Prices had been flat for years, now “up” is the new “flat.” Game console prices used to go down across the length of a console generation, but not this time around. Microsoft’s explanation for the new price hike today: We hoped another price increase would not be necessary, and we have spent the last several months working with suppliers on options. Unfortunately, console storage and memory prices have increased by more than 2.5x and we expect another doubling by the fall of 2027. The entire consumer electronics industry is struggling with the current components crisis, but the effects are particularly hard on consoles. Unlike phones, computers, speakers, and other consumer devices, consoles are typically not sold at a profit, but instead for less than they cost to make. This is an issue well beyond game consoles. Apple announced price hikes on its computers and tablets today as well. Game File is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Subscribe Item 2: Brutal Bungie cuts Bungie laid off “most” of its Destiny development team and some developers who worked on Marathon, the newest game from the struggling Sony-owned studio. A WARN notice issued by Sony to Washington State, where Bungie is based, tallied cuts impacting 292 workers, effective next month. That’s strictly for Bungie/Sony jobs in Washington and wouldn’t account for any elsewhere. The video I clipped below shows the redacted list of Bungie cuts filed to Washington State officials. As you’ll see, I had to scroll for a while… In a note emailed to PlayStation workers and published online, PlayStation game studios chief Hermen Hulst offered the following explanation for these latest cuts at Bungie: This is painful news, especially for talented colleagues whose roles have been eliminated. This decision was made only after extensive discussion and careful consideration, and I want to provide some context on how we arrived here. Over the past several months, together with Bungie leadership, we reviewed the studio’s long-term direction, development priorities, resource needs, and role within our broader portfolio strategy. We explored multiple alternatives before concluding that a reduction was necessary to align the studio’s resources with its current priorities and long-term goals. In 2022, Sony bought Bungie for $3.7 billion. The studio’s marquee game, the multiplayer live service shooter Destiny 2 was losing popularity at the time. Its next game Marathon, released earlier this year, has been well-reviewed but had a slow start. Bungie is renowned for making great shooter games, and Destiny fans have mourned the wind-down of Destiny 2. They’ve also expressed bewilderment over reports that Destiny 3 is not, per Bloomberg, immediately in the cards.
Caitlin Clark made the WNBA bigger. It’s still playing small
The league’s paltry one-game suspension of Alyssa Thomas after her fist to Caitlin Clark's throat barely begins to address the problem.
Injury-hit Warrington dig deep to beat Catalans
Warrington overcome injury problems to move level on points with Leeds at the top of Super League with a gutsy win over Catalans.
Making Our Own Luck
We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.
Ranking Big 12 recruiting classes via average commit distance
The Big 12 recruiting landscape continues to change as programs continue to shuffle throughout the conference. Texas Tech is pushing to sign the nation’s No. 1 class in the 2027 cycle and it firmly sits atop the league’s recruiting rankings. The Red Raiders are the only Big 12 team with a top-25 haul, per the […]
Fox Sports renews Gold Cup rights, adds Nations League
Fox Sports is going to remain a player in the international soccer game for several more years to come. Although the rights for the 2030 World Cup are up for grabs, Fox made the announcement on Wednesday night that the Gold Cup, the CONCACAF championship tournament, will remain with the company. In addition, Fox is…
How should European scientists respond to the US AI kill switch?
Earlier in June, Europe’s worst fears of technological dependence were confirmed when the White House ordered the AI firm Anthropic to stop non-US citizens using its leading models. This kill-switch moment crystalised anxieties in Brussels that the continent, lagging the US on the creation of leading-edge AI models, is now a technological of vassal of Washington. The shock has specific implications for European scientists and universities. Some governments are now worried that with AI being integrated into labs, Donald Trump now has his finger hovering over an off switch for European science. “Having restrictions on this tool, it can have an impact on our own research,” said France’s research minister, Philippe Baptiste, at the VivaTech conference in Paris on June 18.Baptiste, himself a former academic, said that colleagues in mathematics had recently warned him they were now cut off from leading-edge US models, risking their work. “This model is not available anymore now because of the US restriction, and for the first time this had an impact on mathematics,” a field where large language models (LLMs) are making a significant contribution, said Baptiste. So, should European scientists avoid relying on US models in the future? Or would this be a self-harming overreaction? And how is AI being used in science, anyway? What happened?On June 12, it emerged that Washington, citing cybersecurity concerns, had ordered Anthropic to stop non-US citizens using two models: Claude Mythos 5, and Claude Fable 5, a version of Mythos but with guardrails to prevent abuse. Anthropic said Washington’s concerns were overblown. But forced to follow the order, yet with no way to check who was using the models, the company suddenly shut down access for everyone, US citizens included. There’s still no agreement on how to restore broad access. But last week, Bloomberg reported that select US companies, and the US government, still had access to Mythos despite the ban, but the EU’s cybersecurity agency Enisa had been shut out. Class division of researchersIn the longer term, access outside the US should be restored, said Marcel Salathé, co-director of the AI centre at the Federal Polytechnic School of Lausanne (EPFL), because a permanent restriction would be financially ruinous to US AI firms. “Even Trump will eventually budge to economic pressure,” he said.However, US AI firms might end up operating rather like banks, doing due diligence on users of their leading-edge AI models, he went on.European scientists are unlikely to fall foul of such checks, he said. But having a Chinese postgraduate in their lab, or doing a type of research the US disapproved of, could potentially result in access being denied. “It will create a sort of class division of researchers,” he said. More than frontier modelsHowever, successfully deploying AI in science is about far more than just having access to leading LLMs such as Mythos.Instead, many science-specific tools, most famously Alphafold, which predicts protein folding structures, require “far less” computing power to train than frontier models, well within the capabilities of European supercomputers, according to a recent analysis by the Arq Foundation, a Brussel-based AI think tank. Instead, tools such as Alphafold are possible because certain fields, like protein folding, weather prediction or astronomy, have large, clean, standardised datasets that can be used to train predictive models. Rather than compute, “data is the central constraint for AI for science,” the report says. For example, a less powerful physics model trained on CERN’s data “will be more valuable than the best model without certain data,” said Bengüsu Özcan, author of the report. European advantage?Europe could therefore steal a march by using its scientific data and infrastructure to create models US digital giants cannot. “They might actually match or go even beyond what these big [US] companies are doing,” said Özcan.Indeed, some European start-ups hope to create automated testing labs to create the kind of standardised data that could speed up the discovery of new materials. Materials scientists say there’s currently too little data to train models. AI scientistsHowever, even if the bottleneck for AI in science is often data, rather than compute, being at the mercy of the US for LLM access could still become a problem for European scientists. A new class of “AI scientists” based on leading LLMs is also emerging, Özcan’s report says.Unlike domain-specific tools like Alphafold, these try to automate day-to-day scientific work, by providing an overarching tool that coordinates specific models to synthesise existing literature, generate hypotheses or run analysis of data. The problem for Europe, however, is that these tools are sometimes based on US leading models. Google Deepmind’s AI Co-Scientist, for example, is built on Google’s Gemini LLM. Systematic failureThese scientific automation tools are still in their early stages, and still exhibit “systematic failures on scientific tasks,” Özcan’s report says. One of the problems is that the messy, day-to-day process of scientific discovery is largely not documented, meaning LLMs don’t have a good source of data to learn how scientists actually work. Meanwhile, some tasks, such as literature synthesis, don’t typically require access to leading edge models.However, the performance of AI scientific assistants could improve as companies such as Google pour resources into developing them. Rely on US“Unfortunately, for scientific assistants, there is not much we can do right now except rely on US frontier AI,” said Antoine Bosselut, a natural language processing expert based at EPFL. Chinese-built open models, which can run on local computers, lessening the risk of a shutdown, are touted as one alternative to US dependence. There’s also Mistral, once seen as Europe’s main AI hope, but the Paris-based company has seen its recent models fall behind in performance. But the Chinese alternatives are generally not as capable as US frontier AI models, said Bosselut, unless paired with fiddly, custom tools that allows them to act as independent agents. “Most scientists do not have the time,” he said. Don’t jump ship yetAlthough the kill switch moment is seen a warning shot for European scientists, it doesn’t mean labs should abandon US AI tools immediately. “I do not think the right response is simply to abandon US-based models and systems under the banner of sovereignty or independence,” said Mattias Björnmalm, secretary general of the Cesaer university association. “That would be an overreaction.”Related articlesEuropean sovereignty in AI requires ‘ugly trade-offs,’ say experts Robotic lab start-up makes case for €500M EU-funded materials testing facilityAI in science: is it useful? Instead, European researchers need to ask themselves whether they’re becoming dependent on technology that could be turned off in Washington, said Özcan. “They might not see this today, but they should really start asking this question,” she said. European researchers need a plan B, said Salathé. “I would recommend to every researcher, very proactively explore alternatives.”Own toolsIn addition, Björnmalm and others want European research institutions to develop their own scientific AI tools.Instead of signing AI deals with US digital giants, European universities should be using this money to create their own models, which may end up being superior for research, said Sabine Leonelli, an expert on the use of AI in science at the Technical University of Munich. “Universities in Europe seem to be happy to sign commercial contracts with US companies on the assumption [their AI tools] are better,” she said. But US frontier LLMs are typically opaque, and have been developed without independent scientific input, she said. “This is not good enough for science.”Last year, Swiss researchers released Apertus, an LLM designed to be completely transparent, from its development methods to its training data. The idea is that this makes scientific tools built on top of the model far more reproducible than with closed, commercial alternatives.“Europe needs more of this: serious capacity-building that gives researchers, universities and companies credible options,” said Björnmalm.
TikTok and YouTube are reinventing sports viewership. Broadcasters are taking note
Leagues, teams and media networks are increasingly meeting younger fans on social media as platforms like TikTok, Roblox and YouTube capture most of their time.
TikTok and YouTube are reinventing how young fans watch sports
Sports TV ratings and live rights fees are soaring, but professional leagues and broadcasters are facing a new battleground for young fans. Social platforms like TikTok and YouTube are claiming an increasing share of viewing hours among Generations Z and Alpha. Sports clips, highlights and creator content can introduce younger fans to professional sport, but how do the major players cash in?
Keiser's Paul Dodson Voted 2025-26 SUN Sports Information Director of the Year
The Sun Conference is pleased to announce that Keiser University Assistant Athletics Director of Communications Paul Dodson has been named the 2025-26 Sun Conference Sports Information Director of the Year, as voted on by his peers across the league. The honor marks the third conference SID of the Year award of Dodson's career after previously earning the distinction in 2022-23 at Keiser University and 2018-19 while at Johnson & Wales University.
Tamworth sign duo Dyson and Bailey
National League side Tamworth sign midfielder Oliver Dyson and left-back Joshua Bailey.
Bologna open talks for Rangers' Raskin
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