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Weather emergencies disrupt Trump’s Fourth of July plans
Officials evacuated attendees from the Salute 250 program, where President Donald Trump was expected to speak ahead of a record-breaking fireworks show.
On busy holiday weekend, Lake Geneva businesses try to rebound from storms
One day after deadly storms wreaked havoc on Lake Geneva, the town's businesses are feeling the affects on one of their busiest weekends of the year.
Scientists may have finally solved the black hole information paradox
Researchers have proposed that black holes stop evaporating at the last moment, leaving behind tiny remnants that preserve all the information they contain. The same seven-dimensional geometry behind this idea could also help explain why elementary particles have mass.
Physicists Simulated a Black Hole in a Lab. Then It Started to 'Evaporate'.
A glimpse into darkness.
Beach water warnings ahead of Fourth of July holiday due to elevated bacteria levels
Health officials were warning beachgoers to avoid entering the ocean at several locations due to elevated bacteria levels that could make people sick.
Securing a high-character goldmine preserves Cowboys draft investment
It is still unbelievable that Caleb Downs fell to the Cowboys.
Breast cancer
WHO fact sheet on breast cancer, including information on prevalence, risk factors, symptoms, management, global impact and WHO's work on breast cancer.
Pickleball tournament raises over $40,000 for community health center
Through three days of pickleball, Elevated Community Health’s 2nd annual Elevated Paddle Battle tournament raised over $40,000. The tournament, which ran from June 26-28 in Breckenridge’s Carter Park, featured 100 players from 12 states, all...
Long Reads for the Long Weekend
(Welcome to the Entertainment Strategy Guy, a newsletter on the entertainment industry and business strategy. I write a weekly Streaming Ratings Report and a bi-weekly strategy column, along with occasional deep dives into other topics, like today’s article. Please subscribe.) Happy Fourth of July weekend! As has been a tradition of mine going back to the beginning of the EntStrategyGuy website, I’m sharing my favorite long reads of the last year, like I did in 2019, 2020, 2021, 2024, and 2025. Let’s dive right in! Subscribe “Different Prices for the Same Ride: How Uber and Lyft Use AI to Get More Money Out of You“ by Derek Kravitz in Consumer Reports I don’t think surveillance pricing, like the kind described in this brilliant Consumer Reports article, is long for the world—it’s toxically unpopular—but we’ll see if either party takes on this issue. If I ran a political party focused on affordability, I would focus on a few pro-consumer and pro-market policies: Banning non-compete agreements. Ending surveillance pricing Eliminating junk fees (read more here...) Ensuring “right to repair” for consumer (and military!) products Capping excessive app store fees Stopping digital/algorithmic price-fixing tools. Preventing automatic subscription price increases. And more. If you want to fight inflation, there are a lot of great ways to do it quickly. Speaking of higher prices... “Secret Documents Show Pepsi and Walmart Colluded to Raise Food Prices Across the Economy“ by Matt Stoller in BIG Again, I think a political party should focus on lowering prices for consumers. And deals like this—Walmart making a deal/forcing Pepsi to offer the lowest prices at its stores and nowhere else—hypothetically lower prices at Walmart...but raise them everywhere else. “15 DUIs, still driving: California’s failure to take repeat drunk drivers off the road“ by Robert Lewis and Lauren Hepler in CalMatters CalMatters does terrific reporting in California, something the Golden State desperately needs more of, and this article is a great example of that. “PugLips: The next insanely popular thing you’ve never heard of…” by Simon Carless in Game Discover Co I thought that this parody article (and yes, it’s a parody, but I was definitely unsure at first) was hilarious and totally nailed how much tech/business journalism feels these days. Actually, three of my favorite articles this year were on hype in the video game industry, including Georg Zoller’s “The Video Game Industries Very Dark Night”—which I linked to recently and wrote a follow-up here—and Owen Mahoney’s “Derek Zoolander, Videogame Exec”. In particular, I like Mahoney’s focus on user experience as a guide to what trends will actually grab hold of customers. “The Matrix Lies“ by Evan Shapiro in Media War & Peace Evan Shapiro’s first person account of his experience with AI was hilarious. I think LLMs capabilities have significantly grown from last summer, and yet...my editor/researcher just had an abysmal experience using an LLM to do a quite basic task (which our LLM normally does each week) and the LLM made a mistake on every single data entry...along with seven different mistakes affecting twelve of the twenty or so entries, including mistakes that are explicitly spelled out in the prompt. That’s a brutal failure rate. Again, if you use AI/LLM for data collection, you need to take a lot of extra steps to verify and check the data. “Ghosts in the Balcony: A Cross-Country Trip to 58 Theaters Fighting to Survive“ by Matthew Frank in The Ankler I thought Matthew Frank’s pitch to head across America to visit theaters sounded insane aggressive at the time—at least it felt that way to someone a decade older than him; man, to be in your twenties again, am I right?—but I knew the result would be great. And it was, a terrific feature by a great young writer. Also, I loved Matthew’s recent article on who’s getting the precious few entry level jobs in Hollywood. (Hint: nepotism.) “Disney erased FiveThirtyEight“ and “Did Las Vegas get too greedy?” by Nate Silver in Silver Bulletin I love media history and analysis, and there’s no one better to get the history of FiveThirtyEight than from Nate Silver, who wrote about his personal experience in one of my favorite pieces from this year. I also loved Nate’s breakdown of what’s causing Vegas’ woes, but I’ll offer one criticism, summarized as “Might I suggest antitrust?” Many centrists/center-right/libertarian thinkers (Nate is self-described as the latter) often don’t consider consolidation or antitrust as factors in policy issues like housing, America’s military readiness, or, in this case, Las Vegas. Even if libertarians want to debunk antitrust/consolidation concerns, I’d love to read that debunking. In this case, Vegas is incredibly consolidated (though it also has been for a long time) and I’d have loved to read Nate at least contending with this factor, since he addresses almost every other potential factor for Vegas’ decline. “Why Microsoft’s Carbon Removal Pullback Is Such a Big Deal“ by Robinson Meyer in Heatmap News I’m a big supporter of carbon removal efforts, but this nascent industry faces a lot of headwinds, including this big move most recently. I think it’s clear that solar panels and batteries should be able to get the world to its carbon footprint goals, but effective carbon renewal remains necessary to prevent the worst impacts of global warming. “AI is killing the cheap smartphone“ by David Oks LLMs and AI will impact the world in ways we’re not ready for, and already, third world countries are seeing the prices of cheap cellphones skyrocket due to the cost of chips skyrocketing. This article by David Oks is a terrific breakdown. “100 Days of Madness: Netflix, Paramount, Warner and the Future of Hollywood“ by Wade Major at Hollywood Heretic Wade Major dove deep into Hollywood/streaming’s financials in this must read piece. Not that I agree with everything in this article (read my take on Warner Bros./Paramount here) but the analysis is top notch. I think many people discount how quality thinking, regardless of the argument/conclusion, will make you a better thinker. “Erased by the UFC: Frank Shamrock, The MMA GOAT of the 20th Century“ by Nate Wilcox in The MMA Draw Newsletter Growing up playing the UFC fighting game on the Dreamcast, Frank Shamrock was my favorite MMA fighter, and this history/tribute to him was great. Other Fun Reads “The Hardest Part Of History To Tell Is How It Felt“ by Craig Fehrman at Defector “Unmasking the Sea Star Killer“ by Craig Welch at bioGraphic “What Could Save the Industry? Fin-Syn“ by Richard Rushfield in The Ankler Alex Rollins Berg in Underexposed on movie bumpers, pillow shots, Disney trash cinema, cult films, and Casablanca. David H. Montgomery in YouGov’s The Surveyor on punctuation marks, condiments, dinosaurs, and comic strips and kids media. “How Medium finally pivoted its way to profitability“ and “Why the best journalists on YouTube are all former Vox employees“ by Simon Owens in Simon Owens’s Media Newsletter “It’s Not Just You, Netflix Shows Have Gotten Slightly Shorter: Here’s What the Data Says“ by Kasey Moore at What’s on Netflix “Numlock Awards: How Diane Warren became the biggest loser in Oscar history“ by Nathaniel Rakich and “Numlock Awards: The Oscar Bait era is over. The Oscar Chum era is here.” by Walt Hickey & Michael Domanico at Numlock Awards
Xtalks Announces its Life Science Webinar Calendar for July 2026
Stay on top of current hot topics through free webinars presented by leading experts in the pharma, biotech, medical device and food industries. Access to all webinars is free, so be sure to register today to save your place! Participate in the discussion and stay relevant in your field!
We Could Seed Alien Life Elsewhere in the Universe—But We’ll Never Undo the Devastating Consequences, Scientists Caution
This “would be equivalent to a planetary invasion,” expert warns.
Venezuela's infrastructure long a disaster waiting to happen
Even before June's devastating earthquakes, Venezuelans experienced electricity outages that affected the supply of drinking water, as well as serious failures in public services, transportation and telecommunications.
Richard Hughes has the perfect midfield signing for Liverpool
Liverpool's midfield is one of their main areas that needs to be revamped. Alexis Mac Allister and Ryan Gravenberch both failed to meet expectations last term with their inability to run one of their ...
Saving science as we know it: Overview of new proposed rule from the Office of Management and Budget, and how we can make our voices heard.
The Office of Management and Budget has proposed to completely restructure federal funding for science as we know it. In this bite, we review the most relevant points in the proposal and describe how to submit public comments on it by the deadline of July 13th, 2026.
Nevada’s FY26 preliminary business sales revenue increases by 3.8%, Secretary of State Francisco Aguilar says
State's preliminary business sales revenue is $226.6 million, according to officials.
Which schools will play which sports in the new-look Mountain West
The Mountain West used to have a clean-cut approach to its membership with 11 full members plus two affiliates (Hawaii in football and Colorado College in women
FDA clears AI-enabled CCTA plaque analysis tool from Keya Medical
The company now has multiple FDA-cleared algorithms for evaluating CCTA results.
Why you should wash new clothes before wearing; signs that you are aging well; effective leadership in health care; plus other stories with Vanderbilt Health sources
Jami Miller, MD, Professor of Clinical Dermatology, and David Gaston, MD, PhD, Assistant Professor of Pathology, Microbiology and Immunology, are quoted in a Southern Living piece about the importance of washing new clothes before wearing them. Dyes, chemicals, mold and bacteria are all potential troublemakers lurking around your new duds. Parul Goyal, MBBS, Associate Professor of Clinical Medicine, was quoted in a Huff Post story outlining signs that you are aging well. Tae Kon Kim, MD, PhD, Assistant Professor of Medicine, was interviewed by Healio for a story headlined, “Effective leadership in health care ‘starts with listening.’” AAMC News reporter Patrick Boyle interviewed Wes Ely, MD, Professor of Medicine and Critical Care, for a story about ICU delirium. PharmaVoice reporter Kelly Bilodeau interviewed Romney Humphries, PhD, Vice Chair and Executive Medical Director, Clinical Services, for a story about the CDC’s new data that shows an alarming increase in the prevalence of a gene that can make “nightmare bacteria” significantly harder to treat. American Community Media interviewed William Schaffner, MD, Professor of Preventive Medicine, for a piece about Ebola that was reused by several media outlets around the U.S., including The Mississippi Link. Stacie Dusetzina, PhD, Professor of Health Policy, was quoted by The Independent in a story about how Medicare will soon cover weight-loss drugs. Courtney Schadt, MD, Associate Professor of Dermatology, was interviewed by Tennessean reporter Beth Warren, about tanning safety and tanning fads circulating social media. WKRN News 2 interviewed Amanda Peltier, MD, Professor of Neurology, about the correlation between head trauma and ALS following the diagnosis of former Titans running back Chris Johnson.
Elevance sues government over $115 million tied to Medicare Advantage star ratings
The health insurer says CMS didn't calculate its star ratings appropriately.
The best movies of 2026 so far, from ‘Project Hail Mary’ to ‘Rose of Nevada’
The best films of the year so far include “Project Hail Mary,” “Disclosure Day” and “Nirvanna the Band the Show the Movie.”.
Galaxy S27 Ultra Won’t Embrace Silicon-Carbon Battery Due To Manufacturing Costs, But That Doesn’t Mean Samsung Isn’t Evaluating A Bigger Capacity
Samsung is rumored to be evaluating a higher battery capacity for the Galaxy S27 Ultra, but cost increases is why it won’t switch to silicon-carbon
http://democrats-energycommerce.house.gov/media/press-releases/republicans-disastrous-health-care-agenda-leaves-millions-americans-without
House Energy and Commerce Committee Ranking Member Frank Pallone Jr., D-N.J., and Senate Finance Committee Ranking Member Ron Wyden, D-Ore., today released their latest report monitoring the devastating impact of Donald Trump and Republicans’ Big Ugly Bill, which has forced millions of Americans to face skyrocketing health care costs and even drop coverage entirely.
Nevada imports surge 492% since Great Recession, report finds
National Association of Realtors data shows that Nevada’s import industries, including distribution and logistics, have grown exponentially since the Great Recession.
What’s going up on Airline Highway, near Coursey Boulevard?
The first phase of construction started in May, according to a Facebook post by Centurion Construction Management, the general contractor.
Patient enrolment begins in a scientific trial to identify the first effective treatments for Bundibugyo virus disease
In a major international effort to evaluate potential treatments for Ebola disease due to Bundibugyo virus (BVD), the PARTNERS clinical trial has opened enrolment today for patients in the Democratic Republic of the Congo.
Croatia criticised for ‘unambitious’ changes to 2022 science law
Croatia’s science ministry has been accused of a lack of ambition, and even incompetence, over proposed changes to the country’s 2022 science law. Critics say an opportunity has been missed to fix wider shortcomings in the research and universities system.“This law, like all the previous ones, will not significantly change the current state of science in Croatia,” Vlatko Silobrčić, a member of the Croatian Academy of Sciences, told Science Business. “A small shift here and there will not have a significant impact.”The 2022 law introduced multi-year block grant financing of research, based on results, and changes intended to boost employment and career progression for researchers and lecturers. But implementation of the law has been uneven. “It became apparent that certain of its provisions were subject to different interpretations by higher education institutions and scientific institutes,” the science ministry said in its proposal for change. “This caused legal uncertainty in the system, administrative difficulties in implementation and, in certain cases, unequal treatment of teachers, scientists and students.”Most of the proposed amendments deal with technicalities in hiring and promoting staff, such as extending the committee deadlines from 60 to 90 days, or allowing applicants to cite all of their achievements and not only those since their last appointment.Both the ministry and Croatian media highlighted changes that would raise the retirement age from 65 to 67 years and allow part-time students 15 year rather than 10 years to finish their studies.The change to retirement age has been criticised for reinforcing a weakness in the system. According to Matko Marušić, professor emeritus at the University of Split, this will “allow unproductive teachers to advance and work longer, while hindering and discouraging productive ones.”A longtime campaigner for excellence-based meritocracy, he sees little hope in the new legislation. “I am not optimistic that things will improve,” he told Science Business. “As recent changes to the law in Croatia show, the legal framework is becoming increasingly hypocritical and harmful.”For Marušić, who analyses Croatia's university system in a recently published book, the situation is “unfavourable and constantly deteriorating” due to the criteria used for academic advancement.“The key criterion for advancement should be scientific productivity,” he said. “In Croatia [. . .] scientific criteria are increasingly lowered, and ineffective and absurd criteria such as waiting times for promotion and age limits for remaining in a job are promoted.” He would also like to see better criteria for the quality of teaching at universities. “In practice, teaching is not monitored or evaluated,” he said, estimating that up to a third of teaching simply does not take place. “Under the guise of university autonomy and bad laws, universities and faculties are allowed to earn additional money by increasing enrolment quotas that have nothing to do with the needs of the labour market.” Lack of ambitionDora Kršul, a reporter at Telegram.hr who covers science policy in Croatia, finds the rationale for changes “bizarre.” “The ministry responsible for supervising the uniform application of the law is changing the law because it is being implemented unevenly,” she said. “This primarily speaks to the power relationship in the sphere of science and higher education in Croatia, that is, the question arises as to who actually manages this system.”Rather than raising quality, she continued, the changes appear to be designed to help vocational and applied universities who have not been complying with the law.The Independent Union of Research and Higher Education Employees of Croatia said that the changes were “unambitious” and represent a missed opportunity for more important changes. “We think some of the changes are even negative,” it said in its statement on June 25. One of these is introduction of an “assistant” job title that allows people to be hired only for the duration of a project. Related articles: Elections to top science bodies test Croatia’s gender equality in researchSlovakia revises R&D approach to increase focus on competitivenessLatvia pilots citizen engagement in research grant evaluationsThe union’s president, Tvrtko Smital, who was part of the 15-member working group tasked with drafting the changes, told the local media there was a “worrying lack of ambition” in the process, and “lack of competence” in terms of research experience and understanding the problems in the system.“There is no clear will to deal with the problems,” said Smital, an assistant professor of marine and environmental sciences at the Ruđer Bošković Institute in Zagreb. “It’s a combination of unambitiousness and incompetence,” he went on, expressing his “deep frustration” with the situation. “There is no strategy, no clear thinking, and money is not being spent optimally.”Croatia’s science ministry has not responded to requests for comment.
New York Jets News: Karl Dunbar Leads Revamped Defensive Line
Your daily links to the New York Jets
Elevance pays CMS $342M to assuage concerns of noncompliance and overbilling
The Medicare Advantage insurer said the payout is equal to what a CMS audit stated was the total amount the company was overpaid for patient care services. Despite receiving the cash, the agency has yet to officially withdraw its enforcement action, as the two parties are still negotiating.
As Aspen Acres Fire continues to burn out of control, Colorado businesses step up to help evacuees
Dodgers Give Devastating Update on Will Smith
Dodgers catcher Will Smith's neck is not getting any better, according to manager Dave Roberts, and his return is looking longer overall.
Early departures indicate Golden Knights are revamping their bottom six
The beginning of the free agency period often makes it clear what vision teams around the NHL are trying to put together for themselves.
NC lawmakers send bills targeting gangs, mental health evaluations to Stein
The House of Representatives on Wednesday passed two bills targeting criminal suspects: one would change where they are evaluated for mental illness while the other would give prosecutors stronger tools to crack down on gang activity.
Marion County warns Oregon behavioral health rules put staff, residents at greater risk
KATU ABC 2 offers coverage of news, weather, sports and community events for Portland, Oregon and surrounding towns, including Beaverton, Lake Oswego, Milwaukie, Happy Valley, Gresham, Vancouver, Hillsboro, Oregon City, Tualatin, West Linn, Woodburn, Tigard, Tualatin and Garden Home.
Metroid Ravenous For Switch 2 Seemingly Leaked In New Rating
It's certainly believable given the timeline
Apple’s iPhone 18 Pro Max eSIM Model To Pack A Mammoth 5,425mAh Battery, While Physical SIM Buyers Get Predictably Shortchanged On Battery Capacity
In keeping with the prevailing divulgatory trend, the latest tidbit has detailed the battery capacity within Apple's iPhone 18 Pro Max.
PAHO launches US$24 million appeal to support health response following devastating earthquakes in Venezuela
Washington, D.C., 1 July 2026 (PAHO) – The Pan American Health Organization (PAHO) has launched a US$24 million emergency appeal to support the first six months of the health response and early recovery following the devastating earthquakes that struck Venezuela on 24 June.
If you’re at risk of Alzheimer’s, these dietary habits can help, study finds
Research suggests diet remains a relevant factor for brain health even after blood markers of dementia are present.
Affordable Healthcare Emerges as a Voter Priority in Purple Nevada
The Trump administration’s cuts to Medicaid and SNAP may complicate Republican Gov. Joe Lombardo’s reelection chances.
How a new super PAC formed to counter AIPAC is fueling democratic socialists’ wins
American Priorities, which started just six months ago, has quickly emerged as an influential force in House Democratic primaries, spending at least $5.6 million to boost Democrats who are fiercely critical of Israel. It helped democratic socialist Melat Kiros defeat Colorado Rep. Diana DeGette on Tuesday.
Exclusive: GOP think tank pushes heavy health spending cuts
The Paragon worldview is likely to remain highly relevant for the remainder of the Trump administration.
Treat Your Health Like A Private Equity Firm For Better Leadership
Disciplined investors have a specific way of evaluating and improving assets. Here's how executives can use that same lens to optimize their health and leadership.
The "Father of the Internet" is finally retiring
Vinton Cerf, one of the creators of the protocols underlying the internet, will step down as Google's chief internet evangelist next week.
How Wisconsin Used Foxes And Deer To Revamp Science Education
Public input identifying over 100 million trail cameras photos of Wisconsin’s animals has transformed science education and state wildlife management.
Mamdani comparisons follow Colorado Democrat into pivotal House race after primary win
Manny Rutinel wins the Democratic primary in Colorado's eighth district, setting up a high-stakes challenge against incumbent Rep. Gabe Evans.
What 124 Future Business Leaders Really Think About AI and Work
Insights from 124 career assessments written by UMD-Smith graduate students show 98% expect artificial intelligence to transform, not eliminate, their careers. The analysis also found AI raises performance expectations while increasing demand for strategic thinking, AI literacy, ethical judgment and critical evaluation of AI-generated work.
What’s being built, bought and planned in Ascension Parish
Here are the latest property transactions, issued permits and upcoming business-related events in Ascension Parish. Property transactions Local organization American Soldiers Evaluation Services purchased a 4,000-square-foot office building on East Josephine Street from Nolan and Sharon Aikens for $400,000. American Soldiers Evaluation Services’ CEO, Dr. Sandrine Nkouga, represented the buyer in the transaction. ASES provides […]
Ingram couple reopens their business after devastating floods
One year after floodwaters surrounded them, destroying their home and business, Jack and Jennifer Hudson have bounced back.
The End of Independent Federal Agencies Will Change Your Business
For executives, the U.S. Supreme Court’s decision in Slaughter v. Trump will likely lead to less certainty and consistency for the regulated aspects of their businesses, with federal rules and their enforcement increasingly determined by political expediency rather than expert analysis. Specifically, there are five ways in which all U.S. businesses will be affected: regulation will become more informal and less transparent; consistency across administrations will disappear; oversight by Congress and the federal courts will be diminished; expert advice will be devalued; and politically-connected lobbyists will drive decision-making. In this environment, business leaders will need to plan accordingly, honing their ability to shift strategy, perhaps dramatically, after every election—and perhaps even during administrations.
Are the 49ers better or just a little bit different?
The 49ers added Mike Evans and Raheem Morris, but are they better?
Did People In The Middle Ages Really Believe The Earth Was Flat?
Medieval people did not need Columbus to prove Earth was round — but later centuries needed that myth.
Molecular imaging pioneer Eva Nogales awarded the 2026 Vanderbilt Prize in Biomedical Science
The Vanderbilt Prize in Biomedical Science recognizes scientists who have a stellar record of research accomplishments.
PAHO expands health response as Venezuela faces mounting health risks after devastating earthquakes
Caracas, Venezuela/Washington, D.C., 30 June 2026 (PAHO) – The Pan American Health Organization (PAHO) is expanding its support to Venezuela's Ministry of Health following the two powerful earthquakes that struck the country on 24 June, deploying technical experts, coordinating international Emergency Medical Teams (EMTs), assessing damaged health facilities, and mobilizing emergency medical supplies to support lifesaving care and reduce the risk of disease outbreaks.
Reaching communities close to hostilities in Ukraine
Primary health care teams in Ukraine are reaching 121 locations within 60 km from active hostilities. This is part of the largest primary health care intervention in frontline areas in the country. European Union (EU)-supported teams are delivering essential services to people trapped by constant shelling and severe security constraints in 7 regions where no pharmacies operate, no health facilities function and evacuation remains impossible for residents.
Venezuela Health System Strained After Earthquakes, WHO Says
By Emma Farge GENEVA, June 30 (Reuters) - Venezuela's healthcare system is under significant strain, the World Health Organization said on Tuesday, with some hospitals damaged and others missing staff after deadly twin earthquakes last week. More than 1,700 people have been killed and 5,000 ...
Short-sighted new student loan caps elevate chiropractic care over critical health care professions
“This administrative logic is hopelessly out of touch with the empirical reality of American health care,” writes David S. Shapiro.
What Botox, rat poison and venoms can teach students about science
New University of Nevada, Reno course builds scientific thinking skills for future science-related fields
Gavin Newsom signs law limiting mental health diversion for people accused of crimes
A new California law gives just more flexibility to keep defendants in jail rather than releasing them to community-based mental health treatment programs.
An out-of-state private equity firm just paid $8.6M for a local apartment complex
North Carolina-based private equity firm Emerald City Associates has purchased the 246-unit Magnolia Trace apartment complex on North Harrell's Ferry Road near Sherwood Forest Boulevard and Interstate… Already an INSIDER? Sign in. Already an INSIDER? Sign in
Former Tennessee Titans running back Chris Johnson reveals a devastating health diagnosis
Two-time All-Pro Chris Johnson reveals diagnosis at age 40.
College Football Analyst Calls Historic Program No Longer 'Relevant'
College football analyst Paul Finebaum didn't hold back on his thoughts on the University of Michigan and its football program. Michigan won the national championship for the 2023 season, but after the win, Jim Harbaugh went to the NFL, and the program was accused of stealing signs. The program ...
Science and Technology Must Deliver for the Public
The United States has never lacked for scientific ambition. What we need now is a renewed civic commitment to ensuring that talent is harnessed for the benefit of all people. Science can work for everyone. Join us as we build a broader coalition committed to that vision.
How Lenders Evaluate Small Business Loans
Jeanette Mack from Navy Federal Credit Union is here to help you understand what lenders are looking at when considering your small business loan application.
Benchmark Scores Don’t Break. Clinical Reality Does. The Health AI Readiness Illusion.
Nature Medicine's frontier AI evaluation exposes a dangerous gap: models acing medical benchmarks collapse under adversarial pressure, and the FDA has no…
The last, best hope for the Colorado GOP
If the Colorado Republican Party desires to retain any relevancy, let alone wrest back any of the levers of political control in the state, it needs to elect Barb Kirkmeyer in the June 30 primary. To be sure, Kirkmeyer would be a solid candidate for governor in any case, whether or not she shared the […]
AB Science reports completion of the step 3 of phase 1, evaluating the combination of AB8939 with venetoclax for the treatment of refractory or relapsed AML
PRESS RELEASE AB SCIENCE REPORTS COMPLETION OF THE STEP 3 OF PHASE 1, EVALUATING THE COMBINATION OF AB8939 WITH VENETOCLAX FOR THE TREATMENT OF REFRACTORY OR RELAPSED ACUTE MYELOID LEUKEMIA THE COMBINATION OF AB8939 WITH VENETOCLAX GENERATED A 67% OVERALL RESPONSE RATE (ORR) AND A 100% DISEASE CONTROL RATE (DCR), WITH NO DOSE-LIMITING TOXICITIES (DLT) OBSERVED, IN A POOR-PROGNOSIS POPULATION WITH ADVERSE GENETICS TREATED IN THE SECOND - TO FOURTH-LINE RELAPSED OR REFRACTORY SETTING Paris, June 2
Evans Has Reportedly Been 'Unguardable' at 49ers Practice
The future Hall of Famer is stunning teammates in San Francisco, dominating red zone drills and exceeding high expectations as he anchors a loaded arsenal for Brock Purdy.
AHA/ACC/ESC/WHF Expert Consensus Document in Collaboration with HFSA, HFA and JHFS: Second Universal Definition of Heart Failure (2026)
In response to the rising global prevalence of heart failure (HF) and limitations in research, surveillance, and prevention, in 2021 multiple cardiac societies convened to issue the First Universal Definition of Heart Failure, establishing uniform terminology, including a designated Stage B (pre-HF) to identify at-risk individuals.
Prevalence and severity of mental health problems in early-career researchers: a systematic review and meta-analysis
Nature Human Behaviour - Mental health concerns among early-career researchers are increasingly gaining attention. This preregistered systematic review and multilevel meta-analysis quantifies...
Join the world’s coolest science lesson in Geneva
Head to Switzerland for a tour of CERN, the world’s largest particle physics research laboratory, to discover the secrets of the universe.
Politics Now: June 27, 2026
LAS VEGAS (KLAS) — This week on Politics Now with host John Langeler: Nevada gaming regulators approve a new plan to keep Primm alive We speak with the Democrat looking to fill a key seat in …
Efzimfotase alfa demonstrated improvements in bone health in treatment-naïve pediatric patients with hypophosphatasia achieving median difference of 1.67 vs placebo in RGI-C Score at week 25 in MULBERRY Phase III trial
Positive results from the MULBERRY Phase III trial showed that efzimfotase alfa (ALXN1850), an investigational enzyme replacement therapy, demonstrated a statistically significant and clinically meaningful improvement in bone health in children (2 to
Bond girl Eva Green is 'recovering' after suffering an injury on “Wednesday” set
The frequent Tim Burton collaborator has joined the show as Aunt Ophelia Frump.
Bond girl Eva Green is 'recovering' after suffering an injury on 'Wednesday' set
Former Bond girl Eva Green is recovering after suffering an injury on the set of 'Wednesday' season 3, which will see her portray Aunt Ophelia Frump.
‘Inner party turf wars’ hang over annual Florida Republican convention
Byron Donalds and state party chair Evan Power also detailed how they plan to frame Florida’s moderate Democratic candidates as progressives.
Jodi's Journal: The purple city prevails
No matter who emerges in this election, the purple city has prevailed. And I think that's a win.
Space elevators could one day exist, transporting us off-Earth with the push of a button. Here's how they would work | BBC Sky at Night Magazine
What is a space elevator and how would one work? We look at the science behind building an elevator to take us into space.
Black Hills Renaissance Fair draws crowds for weekend of medieval entertainment
The kickoff of the Renaissance Festival started on Saturday
Chicago faith leaders, businesses rally to collect supplies for Venezuela earthquake victims
In Chicago, pastors and businesses across the city are coordinating efforts to send aid after devastating earthquakes in Venezuela.
Local businesses step up to help victims of deadly Venezuelan earthquakes
After a devastating series of earthquakes shook Venezuela, business owners in Columbus have found a way to step in and send help.Hundreds are dead, with thousa
Fallout from USMNT loss to Turkey and previewing the Mbappe-Haaland clash
On today’s show, we look back at the United States’ final group stage match against Turkey and evaluate their readiness for the Round of 32. Manchester City insider Sam Lee joins us to preview the tournament’s first true superstar heavyweight clash as Kylian Mbappe and France square off against Erling Haaland and Norway in a battle for Group I supremacy. Plus, The Athletic’s Jay Harris is back in the studio to break down the latest bracketology, advancement percentages, and qualification permutations for Groups G, H, and I using The Athletic’s World Cup Tracker.
Pro-Israel influencers criticize Vance, but evangelicals remain open to him
Despite attacks from some conservatives, a heavily pro-Israel crowd still has warm words for Vance, with many saying they could pick him as the party’s nominee.
Jeffries Faces Steep Test as Far Left Builds Strength in Congress
The victories of Darializa Avila Chevalier and other anti-establishment candidates are changing the face of House Democrats, posing a challenge for their leader.
CDFW News | Monterey Bay Northern Anchovy and Pacific Sardine Commercial Take Restrictions and Recreational Advisory in Place Due to Public Health Hazard
State health agencies determined that northern anchovy and Pacific sardine recently sampled from Monterey Bay contained elevated levels of domoic acid and recommended a commercial fishery restriction and recreational health advisory in the bay for the take of anchovy and sardine for human consumption in the area.
Horry County business evacuated after reported gas leak
A gas leak in Horry County has caused a business to evacuate.
Gov. DeSantis OKs ‘Charlie Kirk Memorial Avenue’ at FIU, ‘Trump Boulevard’ in Broward
Kirk was shot and killed by a lone sniper on a Utah university campus on Sept. 10, 2025.
Business Leader Tim Giroux Announces Candidacy for Nevada Joint Union High School District Trustee
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Making Our Own Luck
We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.
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