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Buffalo Bills name 6 captains for 2026 NFL season
Who joins quarterback Josh Allen and linebacker Terrell Bernard as an official captain for the Buffalo Bills in 2026?
Father-Son Duo Launch A Talent Discovery And Entertainment Ecosystem For Independent Performers
Father-son duo launch a talent discovery and entertainment ecosystem for independent artists because likes alone don't pay the bills.
Northrop Grumman lands defense contracts worth $1.37B
Falls Church-based defense supplier Northrop Grumman landed two major military contracts collectively worth $1.37 billion.
As Latino shoppers hunkered down, Cook County businesses lost $1.26 billion
Federal immigration enforcement cost Cook County businesses an estimated $1.26 billion in lost sales last year as Latino residents sharply curtailed trips outside their neighborhoods to shop and dine.
As Latino shoppers hunkered down, Cook County businesses lost $1.26 billion
Federal immigration enforcement cost Cook County businesses an estimated $1.26 billion in lost sales last year as Latino residents sharply curtailed trips outside their neighborhoods to shop and dine.
Bills Mafia’s Houston takeover: Where to party before Bills-Texans
Here’s all the information you need if you’re traveling to Houston for Bills vs. Texans
Pritzker, Eyeing 2028, to Help Midterm Democrats With a $20 Million Group
JB Pritzker, the billionaire governor of Illinois, is continuing to expand his national footprint, this time by using a new group to target Republicans in battleground races.
Apple Falls Before Ternus's First $54 Billion iPhone Test
Tomorrow's launch must turn premium hardware into evidence that Apple can close its AI gap.
Roundtable Rams Episode 34
Roundtable Rams crew James Brizuela and Billie Melissa break down the Los Angeles Rams Week 1 showdown with the San Francisco 49ers.
Your vote. Your child’s classroom. Your electric bill. Your water. Your health.
More than 95% of cases in this country are handled by state courts. And as the U.S. Supreme Court pushes fundamental questions about our freedoms back to the states, state courts and state constitutions are increasingly important protectors of our rights.But those protections only mean something if the judges sitting on our Supreme Court are willing to enforce them.
Norman Rock Creek Entertainment District faces lawsuit over tax increment financing
Norman's Rock Creek Entertainment District is a $1 billion project set to open in 2028, including a multipurpose performance venue, restaurants, retail space, office development, a hotel, and multiple housing options.
Rock Creek Entertainment District in Norman faces another legal battle
A judge will hear arguments on Tuesday as the legal battle over the $1.1 billion Rock Creek Entertainment District in Norman heads back to court.
Louisiana concrete companies join forces to capitalize on construction boom
Two Louisiana concrete suppliers are joining forces with two out-of-state companies to pursue large-scale construction projects as billions of dollars in new industrial and technology investment move … Already an INSIDER? Sign in. Already an INSIDER? Sign in
UnitedHealth’s Democrat investment, and surprise billing bloat debate
UnitedHealth execs shower a top Democrats with cash, and the No Surprises Act debate heats up.
AZ's R&D chief Barr touts internal 'science success story' after IL-33 antibody's stellar showing in COPD
With a detailed data drop that AstraZeneca’s R&D chief described as an internal “science success story,” the British Big Pharma has secured an FDA priority review for what it believes could become a flagship biologic in chronic obstructive pulmonary disease (COPD). In detailed results from the late-stage Oberon and Titania trials—first teased in March and detailed in full at the European Respiratory Society Congress in Barcelona this week—the drugmaker laid out the extent of its IL-33 inhibitor’s potential to reduce moderate and severe exacerbations in a wide range of COPD patients still struggling with those “lung attacks,” as AstraZeneca’s Sharon Barr, Ph.D., called them, despite using standard-care inhaled therapy. In the headline results, a 300 mg dose of tozorakimab given once every four weeks curbed those moderate and severe exacerbations in the studies’ primary population of former smokers by 29% in the Oberon study and 34% in Titania. In the overall population of both current and former smokers, these reductions were 30% and 29%, respectively, versus placebo and inhaled standard of care. The benefits also extended to clinically meaningful exacerbation reductions in all prespecified patient subgroups and specifically turned up promising signals in patients across a range of blood eosinophil counts, with Barr telling Fierce that “it’s the details that make this even more exciting than the high-level results that we’ve already shared.” In fact, during AZ’s tozorakimab poster presentation at the ERS 2026 Congress this past weekend, attendees were so enamored by the data that event organizers had to encourage people to clear the room and look at the other presentations on offer, Barr said in an interview. “I think it really speaks to the fact that there is a lot of buzz around these data because the entire respiratory community has been so desperate for new therapies for these patients,” she explained. The respiratory disease continues to represent a “staggering unmet medical need,” Barr said, highlighting the COPD exacerbations that the Oberon and Titania studies homed in on, which she added carry a greater mortality risk than a heart attack. “When a patient has a severe exacerbation, only about half of them are still alive within three and a half years,” she pointed out. As for tozorakimab specifically, Barr christened the molecule “an AstraZeneca science success story,” harkening several years back to the point at which researchers began to explore IL-33 as a driver of respiratory disease, and COPD in particular. At the same time, “there was still so much that wasn’t understood,” she admitted, highlighting the insight that IL-33 signals through both ST2 and EGFR through the RAGE pathway, a discovery Barr attributed to AstraZeneca's own scientists. Understanding the need to tackle both pathways in COPD—and aware of competitor candidates in the hopper, including one that bound ST2—the company ultimately had to make some “courageous decisions,” Barr said. These included taking a prior COPD molecule offline and going back to the drawing board to reinvent its potential IL-33 label “to make sure that we had a molecule that could block signaling through both arms of the pathway, through both the reduced form and the oxidized form, knowing that we wouldn’t be first, but striving to be best.” “When we put [tozorakimab] into the clinic, we firmly believed that we had a differentiated molecule, and we saw the other molecules blocking just ST2 or partially blocking IL-33, unable to deliver two positive pivotal studies in COPD,” Barr explained. “We kept marching forward because we believed our molecule was differentiated, and now I think we have the clinical validation that supports that.” Ultimately, AstraZeneca finds itself on much better footing these days when it comes to potential biologic rivals to tozorakimab in COPD. Sanofi and Regeneron’s Dupixent, for instance, is approved to treat COPD exacerbations in patients with high eosinophil counts, but not low ones. Meanwhile, the future has become cloudier for other next-gen IL-33 candidates from Sanofi and Regeneron, as well as Roche, which have suffered trial flops in recent years. One other potential ingredient for AstraZeneca’s success in its duo of studies was that the company was “ambitious in the trial design, willing to look at an all-comers population,” Barr said, “and willing to enroll the most severe patients.” Prior studies for would-be biologics rivals in COPD “avoided enrolling” those patients, she pointed out. She also highlighted the Big Pharma’s painstaking design of exacerbations in its trial, which “gave us a very rigorous readout,” and pointed to “the extra effort and investment” the company put in to understand the effect of mucus plugs in patients. Barr described mucus production as a “key feature in disease diversity,” noting that mucus plugs—obstructing clumps of mucus that block patients’ airways—are associated with worse outcomes in COPD. In its data announcement, AstraZeneca noted that an integrated analysis of Oberon and Titania found tozorakimab “demonstrated a reduction in patients’ mucus plug score,” with the pharma claiming its biologic is the first to deliver such results in a broad COPD population. “So being able to reduce those mucus plugs, we expect, is an important part of driving benefit for patients who are living with COPD,” Barr said. Again touching on the breadth of the study populations, Barr added that tozorakimab “worked across all eosinophil levels in both current and former smokers across all levels of lung function,” which she suggested “really simplifies decision-making for clinicians, and it allows them to offer therapy to the broadest possible patient population.” In the highest patient eosinophil count group, tozorakimab helped chart a 43% reduction in exacerbation risk, which Barr stressed were “unprecedented data.” In the mid-level group, AZ’s drug delivered a 23% reduction and, in the lowest group, a 34% reduction in eosinophils, which Barr said suggests efficacy “in all patient subgroups.” As for AZ’s recent guidance upgrade on the medicine’s sales opportunity, the lift from a $3 billion to $5 billion range to $5 billion plus was informed by multiple factors, Barr said, including the fact that “in 2024, there were multiple competitors, and there aren’t anymore.” Additionally, “we know that this is a massive unmet medical need, and this is a really incredible set of data that we think will be very convincing to the clinical community,” Barr said. Looking ahead to a potential evolution of the COPD treatment landscape, Barr noted that most patients start treatment in the community with an option like a triple therapy, and for them, having an option like AstraZeneca’s inhaler Breztri will remain a “really important part” of that journey. But of the patients uncontrolled on triple therapy, which Barr described as “about half of them today,” just a “small fraction” are currently eligible for biologic therapy, which she emphasized AstraZeneca is working to change. Understanding that COPD is not a “one-size-fits-all” disease, AstraZeneca is also looking at its antibody drug Tezspire for patients with T2-driven disease, and the company continues to think about new mechanisms for tackling COPD through both systemic and inhaled drugs, Barr said.
Corning Stock Climbs On Multibillion-Dollar Verizon Network Deal
Corning stock rose after the provider of optical communications gear for telecom networks announced a multi-billion agreement with Verizon.
Canada’s retaliatory tariffs take effect as US trade talks stall
Canada enforces $20 billion in retaliatory tariffs on U.S. goods after trade talks collapse, escalating tensions in the North American trade dispute.
Mistral raises €3B as sovereign AI becomes big business
The French AI lab has raised €3 billion at a €21 billion valuation in a Series D round led by Samsung, Scaleup Europe and PSG Equity.
The Latest: Canada strikes back with tariffs on about $20 billion worth of US goods
Canada struck back at U.S. President Donald Trump on Tuesday with tariffs on about $20 billion worth of U.S. goods, in response to his latest round of tariffs on Canada.
He lost $180K in retirement savings, now drives Uber and Lyft at 58
Bill Lewis, a former Wall Street broker, now drives for Uber and Lyft after losing his retirement savings in a failed franchise venture.
More than 1.6 million people die each year from secondhand smoke
The share of the population exposed to tobacco smoke is falling, but more than 2.7 billion people worldwide are still affected
Explainer: Why Air India's funding call has come under political scrutiny in Singapore
Air India's request for about $1.5 billion in funds from its owners — Tata Sons and Singapore Airlines — has sparked a debate in Singapore over state investor Temasek's exposure to the Indian carrier.
Joel Pollak on LA homelessness, Gavin Newsom's bills
California Post opinion editor Joel Pollak joins Cheryl Casone to discuss Mayor Karen Bass being pressed on Los Angeles homelessness spending, President Donald Trump's tax incentives for Hollywood and Governor Gavin Newsom's progressive bills.
FOX Sports’ Nick Wright eviscerates Bills’ Josh Allen for lack of signature win
Josh Allen doesn't have a signature win according to Nick Wright.
Endorsement: No on Proposition 44, a cynical attack on community health clinics
Californians must not fall for SEIU-UHW’s thuggish tactics. Vote no on Proposition 44.
Science ministry to inject $3.49 bl for AI model
South Korea's science ministry plans to invest 4.7 trillion won ($3.49 billion) for a project to develop a homegrown artificial intelligence (AI) model that wil
What to know about Canada’s trade war with U.S. as tariffs take effect
Canada struck back at U.S. President Donald Trump on Tuesday with tariffs on about $20 billion worth of U.S. goods, in response to the latest round of tariffs on Canada
What to know about Canada’s trade war with U.S. as tariffs take effect
Canada struck back at U.S. President Donald Trump on Tuesday with tariffs on about $20 billion worth of U.S. goods, in response to the latest round of tariffs on Canada
Science ministry to inject $3.5 bil. to develop frontier AI model
Science ministry plans to invest 4.7 trillion won ($3.49 billion) for a project to develop a homegrown artificial intelligence (AI) model that will...
Tyson Cuts Outlook as U.S. Cattle Shortage Hammers Beef Business
Photo credit piter2121 - stock.adobe.comTyson Foods lowered its fiscal 2026 profit and sales forecasts Thursday as the historically tight U.S. cattle supply continues to pressure meatpackers. The company now expects adjusted operating income of $1.85 billion to
Canada's 20% tariffs on US goods like milk, steel and golf clubs take effect
President Donald Trump threatened to ban Bombardier aircraft sales on Truth Social just hours before Canada's retaliatory tariffs hit $20 billion in U.S. goods.
Eureka Springs Police Chief creates unique system for enforcing the rules of the permanent entertainment district trial
To make understanding this trial easier, Eureka Springs Police Chief Billy Floyd set up a patrol checklist to track disturbances and how many times they’ve had to remind people of the rules.
Eureka Springs Police Chief creates unique system for enforcing the rules of the permanent entertainment district trial
KY3's Billie Brightman reports.
EBUGs, dress code, other changes the NHL, NHLPA are monitoring as new CBA takes effect
Deputy commissioner Bill Daly and union boss Marty Walsh tell The Athletic what they're watching under the new CBA.
The strong summer may be a good sign for theaters this year
Hollywood's biggest summer box office ever, powered by "The Odyssey" and "Spider-Man: Brand New Day," has analysts betting on a $10-billion year.
Everything to know about Lucas Museum of Narrative Art
The highly anticipated $1-billion building opens Sept. 22. Learn more about its architecture, must-see experiences, rocky start and the questions surrounding "narrative art."
Roma slash 26/27 wage bill by 14%
Roma, as stated by Tony D’Amico, has lowered its wage bill as requested by UEFA to send a positive message to European football’s governing body. The Roman club is moving toward sustainability, wh...
Buffalo Bills WR Predicted to Have Career Year in 2026
The Buffalo Bills could see one of their young offensive weapons take a major step forward in 2026, with a bold prediction pointing toward a career year for Keon Coleman. The second-year wide receiver enters the season with an opportunity to establish himself as a more consistent and productive target in Buffalo’s passing attack. Coleman […] The post Buffalo Bills WR Predicted to Have Career Year in 2026 appeared first on Gridiron Heroics.
$68 billion is up for grabs in Medicaid. Who wants it?
What would you do with $68 billion? That is the size of the decision Indiana is about to make.
The Market Forces Quietly Adding Thousands to Patient Bills
The true cost of “vertical integration”: patients directed to a higher-priced location for procedures. Or forced to buy from their insurer’s wholly owned pharmacy, which may not stock the drug prescribed or provide it at the lowest price.
Now is perfect time for Sebastian Tounekti to step up
Time for Sebastian Tounekti to step up. It’s essentially now or never for Celtic’s inconsistent Tunisian winger…5th September 2026; The Marbill Coaches Stadium, Paisley, Scotland; Scottish Premi...
Health experts, lawmakers push for Pa. kratom regulation; proponents warn they'll fight a ban
In Pennsylvania, kratom and more potent, related products remain legal. There are multiple bills moving through the statehouse that would ban or regulate them. But researchers warn there’s still a lot we don’t know.
UT Health San Antonio invests $1 billion to meet the growing demand for healthcare in South Texas
The multiyear investment strengthens patient care, research and healthcare infrastructure.
Kayshon Boutte Tells Truth About Bills Before Texans Debut
The Houston Texans will have Kayshon Boutte on the field against an opponent with whom he is familiar in the Buffalo Bills. The post Kayshon Boutte Tells Truth About Bills Before Texans Debut appeared first on HEAVY.
What to know about Canada's escalating trade war with the U.S.
Canada struck back at U.S. President Donald Trump on Tuesday with tariffs on about $20 billion worth of U.S. goods. The outcome could resonate far beyond Canada.
What to know about Canada's escalating trade war with the U.S.
Canada struck back at U.S. President Donald Trump on Tuesday with tariffs on about $20 billion worth of U.S. goods. The outcome could resonate far beyond Canada.
Why the Buffalo Bills are Sporting News' pick to win Super Bowl 61
Sporting News' latest annual Super Bowl prediction says the Bills will win their first ring post-NFL merger after breaking through to end their 33-season AFC championship drought.
Remembering ‘Superstar’ Bill Dundee and his unlikely Owensboro furniture business
For a time, Owensboro wrestling fans could buy furniture from “Superstar” Bill Dundee — and have him help deliver it.
French A.I. Start-Up Mistral Raises $3.5 Billion as Part of Strategy Shift
Mistral is trying to keep pace with American and Chinese rivals while offering customers a European alternative for artificial intelligence.
Anthropic drops plans to acquire Israeli AI startup Decart
The companies had discussed a transaction worth roughly $6 billion, but the Claude maker ultimately decided against buying the company after reviewing its business and technology.
Inside Erie Politics: PA House Bill 308
Click here to view this video from erienewsnow.com.
UNC releases statement in support of Bill Belichick
UNC vice chancellor for communications Dean Stoyer released a statement supporting Bill Belichick.
California Wants $7.5 Billion for Science. My Generation Will Inherit
A STUDENT’S VIEW - California may ask voters to authorize billions for scientific research after federal funding cuts. Young Californians have a particular stake in what happens next. California is c
DTU fights to keep union certification before Tuesday deadline
Duval Teachers United needs 498 more members by end of business Tuesday to meet the 60% membership threshold required by Florida Senate Bill 1296 or face a certification election.
NFL Punishes Second-Year Texans Playmaker Before Opener vs Bills
The Houston Texans got bad news about second-year cornerback Jaylin Smith from the NFL ahead of their regular-season opener. The post NFL Punishes Second-Year Texans Playmaker Before Opener vs Bills appeared first on HEAVY.
Bill Belichick says UNC program is compliant with investigation
UNC football head coach Bill Belichick says his program has been compliant with an investigation.
Democrats Condemn NIH-DOD Research Agreement
The Defense Department could tap up to $2 billion in federal research dollars designated for biomedical research, under an agreement signed with the National Institutes of Health.
Legislation to curb political violence continues to stall at Ohio Statehouse
There has been a rise in political violence in Ohio, but bills meant to curb these types of crimes have stalled.
Bills Add Defensive Star in New 2027 NFL Mock Draft
The Buffalo Bills load up on defense in a new 2027 NFL mock draft, adding a star to the mix.
Nearly 1.7 million deaths linked to second-hand smoke in 2023, study finds
More than 2.7 billion people worldwide, including 767 million children, were exposed to second-hand smoke in 2023, contributing to nearly 1.7 million deaths, a Lancet study said on Tuesday. Researchers…
Bill Belichick Finally Opens Up About Ongoing UNC Investigation
North Carolina head coach Bill Belichick broke his silence about the program's ongoing investigation.
MAGA Billionaire’s Ugly Business Baggage Exposed
The revelations come as the midterm race for Georgia heats up on multiple fronts.
Lee Health uses federal grant money to expand rural offerings in SWFL counties
A $1.95 million infusion from the $50 billion Rural Health Transformation Program initiated last year will expand the Labelle site to include a walk-in urgent care clinic and a medical lab.
‘We’re healthy’: Mike McCarthy says Steelers have clean bill of health headed into opener
Unlike predecessor Mike Tomlin, judging by his first weekly news conference as Pittsburgh Steelers coach Mike McCarthy does not believe in 10-15 minute-long opening statements buttering up the upcoming opponent or offering a list of injury updates. So when McCarthy stepped to the podium at the UPMC Rooney Sports Complex
Bills rookie already being punished by the NFL
The Buffalo Bills player is getting an introduction to the NFL.
Could the Cincinnati Reds Be the Next MLB Team Sold?
Frustrated fans and rival executives anticipate a massive ownership shift as the Castellini family weighs a potential billion-dollar windfall amidst mounting pressure to prioritize championship contention.
Bills' Greg Rousseau Predicted To Have Career Year In 2026
Greg Rousseau has never reached double-digit sacks, but I think 2026 will finally be the year he breaks through for the Buffalo Bills.
Tata launches €3.82 billion Iveco takeover that could combine two major African truck networks
Tata Motors has opened its €3
Business Rules Management System Market to Reach $4.20 Billion by 2035 as AI-Driven Decision Automation Accelerates
The U.S. Business Rules Management System Market is Projected to Grow from $0.47 Billion in 2025 to $1.09 Billion by 2035, While Europe is Expected to Expand from $0.54 Billion to $1.36 Billion, Driven by Real-Time Decision-Making, Regulatory Compliance, Enterprise Automation, and Rising Adoption of AI- and Machine Learning-Enabled Business Rules PlatformsAustin, United States, Sept. 07, 2026 (GLOBE NEWSWIRE) -- The Business Rules Management System Market was valued at USD 1.79 Billion in 2025 a
Business Rules Management System Market to Reach $4.20 Billion by 2035 as AI-Driven Decision Automation Accelerates
The U.S. Business Rules Management System Market is Projected to Grow from $0.47 Billion in 2025 to $1.09 Billion by 2035, While Europe is Expected to...
Arizona Land Play Bets on Data Centers and Entertainment to Draw Capital West
Arizona Land Consulting plans a $6 billion to $10 billion Tonopah development mixing data centers, film studios, and an amusement park west of Phoenix.
Bills Named Top Trade Destination For Promising 1,300-Yard WR
The Buffalo Bills could target Houston Texans wide receiver Tank Dell in a trade, an NFL analyst suggests. The post Bills Named Top Trade Destination For Promising 1,300-Yard WR appeared first on HEAVY.
Gmail change may flood your inbox with political email
Gmail's Verified Sender Program launches September 8, 2026, giving U.S. political committees a more reliable path to your personal email inbox.
Barcelona forecast €1.195 billion in revenue for 2026/27
FC Barcelona have now announced their financial figures ahead of the upcoming General Assembly, providing full access to the club members now about the economic situation.The accounts for the 2025/26 ...
Nvidia’s Israeli networking business is booming, and so is its economic footprint
The company’s networking revenue reached $32.3 billion in just the first half of fiscal 2027, already surpassing the previous full-year total. Much of the technology behind the business traces back to Mellanox and Nvidia’s Israeli development centers.
Sen. Jim Justice on breaking Senate gridlock, honoring Medal of Honor veterans, and realities of DC politics
In a wide-ranging interview, Sen. Jim Justice, R-W.Va., details how a private chat saved a national monument bill, shares his candid views on Washington’s partisan gridlock.
Gates-backed TerraPower targets British nuclear power plant start by 2034
TerraPower, the U.S. nuclear developer backed by Bill Gates, expects its Natrium reactors to begin generating electricity in Britain by 2034, its CEO told Reuters, making the UK its first market outside the United States.
Scientists Identify a Nose-to-Brain Circuit That Links Anxiety And Breathing
A new mechanism discovered in mice.
Finland to brief political parties on classified defence shortcomings
The government is preparing a significant number of security-related bills for Parliament this year
Column: Wildfire bill flameout sad for California
It was unprecedented and stunning: California’s governor and top two legislative leaders negotiated a compromise on a big bill — and one house rebelled, refusing to bring it to a vote.
Record revenue! Barça tops €1 billion 💰
FC Barcelona has already made public the figures for the 2025-26 season and the forecasts for 2026-27. Members will vote to approve this balance sheet at the Ordinary General Assembly next Saturday, S...
Ella Langley's rise to superstardom came through 2024 Country Calling
Before Ella Langley broke Billboard chart records with her mega-hit "Choosin' Texas," she played the inaugural Country Calling Festival in OC in 2024.
Josh Allen Has No Words for Wife Hailee Steinfeld’s Announcement
Buffalo Bills quarterback Josh Allen enters the 2026 NFL season with high expectations, earning the No. 2 overall spot on the NFL’s Top 100 Players list — a list voted on by players themselves.After winning the MVP award in 2024 and finishing as the third runner-up in 2025, the dual-threat quarterback, who totaled 39 touchdowns […] The post Josh Allen Has No Words for Wife Hailee Steinfeld’s Announcement appeared first on HEAVY.
You may ask yourself, how did I get here?
Bill Posley presents show military service at Solo Flights
Encompass Health (EHC): This Rehab Hospital Giant Just Raised Its Own Bar Again
On August 5, Encompass Health (NYSE:EHC) reported second quarter results that beat its own expectations by enough to raise full year guidance twice in the same release, first on revenue and then on profit. Net operating revenue climbed 9.6% to $1.597 billion, and adjusted earnings per share rose 10.7% to $1.55. For the largest owner […]
Even Dem court couldn’t abide theft of GOP seats
Thanks to the Colorado Supreme Court, Colorado voters will be able to reaffirm their support for the Independent Congressional Redistricting Commission after the court struck down the Democratic scheme to steal three Republican congressional seats. Billionaire-funded national Democratic groups from New York and Washington, D.C. created the hilariously named “Coloradans for a Level Playing Field,” […]
Andrew Garfield faces backlash after telling billionaires to be 'scared' of his new movie
Sam Dong to expand Hawkins County manufacturing operations
Gov. Bill Lee, Deputy Gov. and Department of Economic and Community Development Commissioner Stuart C. McWhorter and Sam Dong officials have announced the company will create 22 new jobs and
The science behind the beauty business
Some of Europe’s industrial champions may be in retreat, but its cosmetics sector remains a global leader, buoyed by healthy demand, recognised brands and a reputation for innovation."The fact is, the science in cosmetics is better here in Europe than anywhere else in the world,” says Pierre Morvan, CEO of Technature, a private label cosmetics manufacturer located near Brest in France’s northwestern Brittany region. “You have to have good science in order to make the difference, and that is why we invest so much in research and innovation.”Across Europe, the beauty and skincare products sector supports an estimated 3.6 million jobs, including 265,000 employed directly in the industry, according to the Cosmetics Europe trade group.. Cosmetics production contributes an estimated €11 billion to the EU economy, and generated €30 billion in export revenue last year, a €400 million rise from 2024.Technature itself has a global footprint, supplying products for 1,500 brands in 65 countries. Its range of skin gels, facial masks, nail treatments and other products include natural ingredients and extracts derived from plants, such as seaweed, that are developed and refined through science-based analysis and testing.While industry projections point to sustained growth for the foreseeable future, driven by emerging economies and wider availability of exclusive brands that were once chiefly sold by high street retailers, the sector is not immune to the impact of geopolitics and trade wars. The Trump Administration’s tariff threats have dented cosmetics exports to the EU industry's largest overseas market. After the European Parliament approved the EU-US Turnberry Agreement in June, setting a 15% levy on many EU goods, the French Federation of Beauty Companies warned that “exports are falling sharply” and urged the EU to negotiate an opt-out for cosmetics.Technature’s CEO flags South Korea as an emerging competitor, partly due to its assertive marketing efforts. “I would have to say I am a little bit scared,” Morvan says, regarding the growth potential of the South Korean cosmetics industry. “This is why science and innovation are so important if Europe is to remain the leader.”With a workforce of 200, including biologists, chemists and other scientists, around 15% of Technature’s staff work in three research and development (R&D) labs. A similar number work in four quality control and assurance facilities, where science plays a crucial in ensuring product safety in a sector that is subject to the European Cosmetics Regulation.Educational exchange between industry and academiaIn recognition of Technature’s research and innovation, Morvan was selected as one of Brest’s ambassadors to Science Comes to Town (SCTT), a European initiative to strengthen communications and understanding between science and society. Brest is one of three coastal cities in the EU-funded programme, alongside Split (in Croatia) and Kiel (in Germany). From 7-11 September, Brest will host the EU TalentOn contest featuring 100 early-career researchers from across Europe.Morvan appreciates the value of engagement with educational and scientific institutions as well as the home community. For instance, Technature collaborates closely with university partners to enhance its in-house R&D. In addition, it invites students to its labs and sends its own researchers to local institutions. "We absolutely want the students to know what the industry is all about,” Morvan says, noting that seeing science in action can help young people “understand that they can do something real with science, to create something with what they are learning.” He says another important benefit: encouraging new generations of young people to consider a career in cosmetics.Community involvement also raises awareness about Technature and the skincare industry as a whole. “The public gains recognition of the innovative company that we are, and this is important for getting new customers,” Morvan says. One of its recent innovations — tiny, colourful cosmetic pearls that release skin moisturisers on application — was showcased at this year’s VivaTech event in Paris.Morvan holds a master's degree from the Brest Business School and studied animal production and biology in Brest at the University of Western Brittany (UBO), an SCTT partner, and at the University of Tours. He got his start in business in 2002, initially working on using seaweed as a raw material in the food industry before transitioning to cosmetics. Morvan has always been interested in connecting science and business, reflecting one the goals of SCTT to enhance public-private collaboration.The invitation to participate in SCTT was unexpected. “It was a surprise to get a call from the city of Brest saying that they wanted me on this programme,” Morvan recalls, adding that officials were drawn by his company’s R&D. “It's not only theory and science fundamentals. Our science is something that is applicable to the global market — and important for the community.”Science|Business, which connects policymakers, academics and industry through its news reporting, analysis and events, is an SCTT partner.
The core anti-Pangram constituency is phony writers
Welcome to The Closing Argument, our verdict on the news, plus everything The Argument published and appeared in this week. The Verdict, by Kelsey Piper A lot of people hate AI for drowning the internet in slop and displacing human creatives. You might think that these people would be thrilled by a program that can identify and flag AI-generated work. But many people who hate AI also hate Pangram, an impressively accurate AI detector that produces very few false positives, according to high-quality independent research. This loathing found its most recent expression in a bizarre Wired article that amplifies a wide range of false arguments from Pangram skeptics: that AI detectors are racist (they’re not) or ableist (they’re not)1 or don’t work (this one does)2. Rather than starting from the premise that it would be really valuable to have a working AI detector and scrutinizing Pangram to make sure it lives up to that promise, the article starts from the premise that Pangram obviously has bad vibes and sets out to discover why. (One answer: The CEO microwaved lunch during an interview!) Why aren’t writers who resent Pangram more eager to distinguish themselves from posters who are having ChatGPT ghostwrite all their work? There are a few different things at play, but I think one key dynamic is this: These are often the same people. A core constituency for arguments like Wired’s is “writers” who are using AI to write their posts but resent this fact being made public. They stand to lose from AI detectors because AI detectors call them out. Share When Substack announced a partnership with Pangram, a sizable fraction of the platform’s authors rose up in outrage. Some people had experience with other AI detectors that didn’t work, and some felt that AI writing ought to be encouraged — both of which are fair enough. But the fury was fueled by authors passionately insisting that Pangram kept wrongly accusing them on almost every post they published. Pangram can be wrong, especially on short passages. But in the overwhelming majority of cases where Pangram looked at a whole blog post rather than a single paragraph, the program correctly detected work as AI. Even if we can’t be 100% sure in any individual case, we can notice the trend in the aggregate. Wired quotes Sam Illingworth, a professor of critical AI literacy at Edinburgh Napier University, who said, “I don’t think [AI detectors] work. … I think that detectors are prejudiced against certain people.” This spring, he said that he used AI for research and editing; this summer he acknowledged that in addition to research and editing, he also uses it “now and then for a turn of phrase I keep.” Pangram informs us that most of his posts are 100% AI-written (some are mixed AI-and-human) and that 100% AI-written posts started appearing last year. The favorable interpretation is that, as someone whose recent work Pangram consistently mistakes for AI, Illingworth sees Pangram’s flaws firsthand. The unfavorable interpretation is that the tool’s credibility trades off against his own, because its account of who writes his posts is not consistent with his. Illingworth is not alone in insisting the detector does not work. “It’s a Monday night in late July, and I’m pasting my own Substack draft into an AI detector for the first time. Not because I’m worried. Because I’m curious. I wrote every word of it myself, the way I write everything, out loud in my head first, in a rhythm that still carries the accent of a language I learned to think in before I learned to write in this one,” begins one Substack post by an author indignant that Pangram flags her writing as AI. “That’s the part I had to sit with before I could write this.” If you, like me, have worked with AIs a lot, you won’t even need Pangram there. The author of that piece is AI. It is obviously AI! I checked 10 other posts on the blog, and they were also obviously AI! “I have spent 22 years as an award-winning author and essayist. And now this bullshit tool that learned from MY writing is going to accuse me of plagiarism,” popular Substack writer Carlyn Beccia wrote in an anti-Pangram post. “For the last and final time, AI DETECTORS DO NOT WORK.” Here’s what her writing sounded like in 2020: “Most success stories revolve around one person who believed enough in you to say — give it a try. We call these people muses, but they are so much more than that. They are the strong man giants whose shoulders we stand on so we can see the horizon. Throughout the editing process, I am sure my editor felt less like a giant of greatness and more like Atlas with the world on her shoulders.” Pangram says it was 100% human-written. (So were other articles of hers in 2020.) And here’s what it sounds like now: “And then there is the reshuffling, which sounds like paperwork until you remember that empires have always loved paperwork. The Trump regime recently moved special education oversight from the Education Department to HHS. That is not a minor bureaucratic transfer. It changes the frame.”3 Pangram says this is mostly AI. I am not convinced that Pangram is wrong. In my own experience, Pangram is very effective on long texts — if it marks a long essay as AI, the essay was either written by AI or deliberately written to sound like AI. On tweet-length or paragraph-length texts, it’s not perfectly reliable. It seems to work just as well for non-native English speakers as for native speakers. While I have seen dozens of claims of pre-2022 text returning a positive result on Pangram, I have tried repeatedly to corroborate those and have never once succeeded. To be clear, I’m absolutely not saying that complaining about Pangram suggests a writer is a cheat. There are plenty of other concerns. Most are mistakenly premised, such as the false claim that Pangram trains on work you put into it, but others are reasonable: It’s unreliable on sufficiently short text segments; it creates an internet witch-hunt mentality when there are defensible uses of AI; people who are open about their AI use are sometimes blamed, when the only people really doing something wrong are the ones who hide it; and it isn’t perfect, so a single positive result shouldn’t be taken as decisive proof of misconduct. I’m happy to concede that Pangram is imperfect and possible to over-rely on. If an author’s posts are mostly non-AI and one scans as partially AI, this could be a mistake. It’s also possible to defeat Pangram with intentional effort. If you think we need something more robust and more reliable, fine! But if you don’t like AI and don’t like Pangram, your attitude really ought to be that it’s a shame that our existing tools for AI detection are imperfect, and it’s important to invent better ones. If your stance is instead that AI is evil and so is looking for AI, then ultimately you’re contributing to the sloppification of the internet. You’re making it harder for people who write their own text to distinguish themselves, and providing cover for authors who are definitely not writing their own text. Subscribe Top stories this week, by Kobe Yank-Jacobs Commentators often worry that the decline of reading could mean the decline of liberal democracy — but deliberative governance actually predated widespread literacy. This week, Maibritt Henkel pointed out that many liberal cultures thrive on a culture of raucous, interactive debate, which can happen in-person as easily, if not more so, than in text. Read on, dear reader, to learn more. It may actually cheer you up: [ ](https://www.theargumentmag.com/p/reading-wont-save-liberalism) [ Reading won’t save liberalism ](https://www.theargumentmag.com/p/reading-wont-save-liberalism) Maibritt Henkel · Sep 1 [ Read full story ](https://www.theargumentmag.com/p/reading-wont-save-liberalism) It used to be bad to downplay climate change (if we mean denying its reality). Today, it’s actually good to downplay climate change (if we mean keeping the issue out of political fights so we can make real progress). This counterintuitive view is called “climate hushing,” and contributor Alex Trembath argued that it’s the key to enacting good policy going forward. Get up to speed on the latest in climate politics: [ ](https://www.theargumentmag.com/p/we-wont-stop-climate-change-by-talking) [ We won’t stop climate change by talking about it ](https://www.theargumentmag.com/p/we-wont-stop-climate-change-by-talking) Alex Trembath · Sep 2 [ Read full story ](https://www.theargumentmag.com/p/we-wont-stop-climate-change-by-talking) Canada’s Prime Minister Mark Carney is standing up for the forces of liberalism against Donald Trump’s assault on our closest ally. So, why is one prominent left-wing commenter attacking Carney? Columnist Matthew Yglesias explains: [ ](https://www.theargumentmag.com/p/when-economic-liberty-means-central) [ When "economic liberty" means central planning ](https://www.theargumentmag.com/p/when-economic-liberty-means-central) Matthew Yglesias · Aug 31 [ Read full story ](https://www.theargumentmag.com/p/when-economic-liberty-means-central) 🌟Abundance Wins of the Week🌟 Shout out to my home state of California, whose legislature passed two housing bills this week. One requires a housing density minimum in transit-oriented areas of the state’s most transit-rich cities (Los Angeles, Sacramento, San Francisco, Oakland, San Jose, San Diego, and Long Beach). Another bill closes two common loopholes used by third parties to delay housing projects, including an opportunity to challenge maps of a given lot created by the developer after a project has been approved. Shout out to our big-state rival, Texas, where pro-housing SB 785 took effect this week. The new state law requires municipalities to have at least one district permitted for manufactured housing without a special permit. This will promote zoning changes in 44% of municipalities. The company Fervo Energy signed a deal with Google for what is set to be the world’s largest enhanced geothermal facility, proving a technology can work at a scale that could be crucial to a decarbonized, energy-abundant economy. Share Worth watching… This week, forecasting legend Nate Silver joined Jerusalem, Matt, and Jeremiah on a crowded episode of the pod. It was a party. And speaking of parties, our round table debated the factional lines within the Democratic Party: Is it possible to be center-left and also anti-establishment? Watch or listen to find out: The Rio Grande Valley in Texas is one of the areas that swung hardest toward Trump in 2024, but musician Bobby Pulido is running to flip it back. Right now, The Argument/Split Ticket’s model has him running 1.1 points behind his Republican opponent in a district Trump won by 18 points. Tune in to find out how he differs from national Democrats and what he thinks he can to do win this seat. On Thursday, Bernie Sanders was among the first politicians to call for a ban on superintelligence. My guest this week, Andrea Miotti, has been lobbying to ban superintelligence for several years, most recently in the U.K., U.S., and Canada. I asked him how he gets legislators to take speculative risks seriously, and we dug into what plans might look like to actually pass a ban. Listen to learn more: What’s News with The Argument The Argument recommends, by Kobe Yank-Jacobs If we ever lose track of Justin Zuckerman, I’ll have the team split up and check all the movie theaters in the city. I’m shocked (and a little jealous) at how often he gets out to see good cinema. This week, he brings us It Ends, a “horror-ish movie,” which he described as a “Gen Z Waiting for Godot.” I was intrigued before he added that it was “funny, dark and existential” — at which point I was fully locked in. I guess I also had existential themes on the mind this week. One morning, a single line from a poem I read long ago just came to me: “Is death a stretch of time in which a life is just a flash?” The poem is called “From 20,000 Feet” by Heather McHugh. I suggest the version in The Vintage Book of Contemporary American Poetry, which, by tradition, my best friend and I always bring backpacking, extra weight be damned. We’ll stay thematically dark for just one more rec from senior editor John Robert Thomason, whose upcoming trip to Baltimore reminded him to suggest Michael Clune’s memoir White Out (about being addicted to heroin in Baltimore in the 1990s). Ben Lerner’s blurb called it _“_Disturbing, brilliant, hilarious—it’s as if Proust had written Jesus’ Son.” John told me this “seems accurate, with the caveat that I’ve never read Proust.” I, personally, have also shelved Proust until retirement. At this point, I was a little concerned for the team since all of us tossed out such psychologically grim material — maybe we’re all down about the end of summer — but thankfully, at least a few of us were into more upbeat selections. Milan Singh recommended Made In’s 5-quart stainless clad saucier, suggesting he had some fun in the kitchen. Jeremiah Johnson asked if he could recommend yet more Carly Rae Jepsen. Once denied, he offered up Game Changer instead_,_ calling it “the most wildly creative game show, maybe in the entire history of the genre.” Eli Richman mentioned _Lucky, “_a B-tier show with an A-tier cast and an S-tier theme song.” I suppose he was recommending the song, Horns of a Bull. Still, despite these cheerier recs, I couldn’t help but be concerned that we were subconsciously worried about racing toward summer’s end — the end of swim trunks and splashing around. Then a message landed reminding me of the three-day weekend to come. A whole extra day for sunshine. One more swim in the lake. I was grateful this called to mind yet another line from a poem, one by Mary Oliver, the patron saint of every gorgeous summer day (and about whom a documentary is now out). Speaking to God in the poem “Thirst,” she wrote: grant me, in your mercy,a little more time. Love for the earthand love for you are having such a longconversation in my heart. We have merch! We have quarter-zips, keychains, hats, and stickers. Each one is a great conversation starter in its own way. Buy them here. Subscribe More to read: [ The Opening Argument ](https://www.theargumentmag.com/p/seeing-like-an-elite)[ Seeing like an elite ](https://www.theargumentmag.com/p/seeing-like-an-elite) Kobe Yank-Jacobs · Sep 4 What do Americans hear when they watch Sen. Bernie Sanders or Vice President JD Vance rail against the elite? Are they thinking of right-wing tech billionaires? Imperious college professors? Liberal magazine writers? [ Read full story ](https://www.theargumentmag.com/p/seeing-like-an-elite) [ The Weekly Scroll ](https://www.theargumentmag.com/p/god-is-back-on-the-timeline)[ God is back on the timeline ](https://www.theargumentmag.com/p/god-is-back-on-the-timeline) Jeremiah Johnson · Sep 5 This week, we’re talking about Substack’s new religious debates, the continuing MAGA influencer scandal, how to retire from YouTube, and aura battles. [ Read full story ](https://www.theargumentmag.com/p/god-is-back-on-the-timeline) 1 This was a legitimate thing to worry about, but doesn’t seem to be a problem given the actual technology: Marijke Van Vlasselaer, Filip Van Droogenbroeck, and Bram Spruyt’s 2026 paper looks at whether Pangram is less accurate when evaluating the work of non-native speakers of English. It isn’t. That’s because Pangram isn’t really looking at how “unusual” a piece of writing is but whether it has the characteristic patterns of LLMs. The Wired article makes an odd gesture at a different Pangram-is-racist argument. There were several controversies this summer during which upcoming books were canceled after being discovered to be AI-written: “The three novels mentioned earlier — Shy Girl, Daggermouth, and Call Me, easily publishing’s biggest AI-detection scandals — were all written by writers of color.” But come on! As Zvi Mowshowitz put it: “They were not primarily written by people of color. They were primarily written by AIs.” That’s the whole problem! And as my colleague Jeremiah Johnson recently observed with respect to Cambridge’s Arday scandal, a community being unwilling to call out fraud if it’s perpetuated by people of color is not an anti-racist tendency; it is ultimately quite racist. 2 Many non-Pangram detectors don’t work, but many possible airplane designs also don’t work, and no one considers this a general argument against aviation; the thing that matters is whether any detection works. 3 The phrase “empires have always loved” mysteriously became all the rage in the last few years. See here, here, here, here and here. Before 2025, the only use of that phrase I have been able to find is a single Tweet. The logic of the sentence, too, is incoherent in an AI-characteristic way. “...sounds like paperwork, until you remember that empires have always loved paperwork”? Does remembering that make it sound less like paperwork? It’s a craft-ful sentence, but what is it actually saying??
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