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The Vogue Business Fall/Winter 2026 Size Inclusivity Report
Size inclusivity on the runway fell again this season, highlighting how far the industry still has to go.
Funding for populist-right ‘media-political complex’ exceeded £170m in five years, research finds
Handful of billionaires gave huge sums in particular to media organisations that boosted rightwing politicians, says Liam Byrne MP
Trump’s new red line could set the Iran war on a fateful course
On Friday, President Donald Trump said he was considering “winding down” his war with Iran. But a day later, he threatened to “obliterate” the country’s power plants in an escalation that could further tip the conflict out of control.
Microsoft: Removing some Copilots will improve Windows 11
: 'Doze boss admits OS needs smaller memory footprint, fixes for old issues like bad Bluetooth, more prominent WSL
Scientists Open Moon Rocks Locked Away Since 1972 – and Find Something Totally Unexpected
Decades after being sealed away, Apollo-era lunar samples are revealing unexpected chemical signatures that challenge long-standing assumptions about the Moon’s composition.
Alcaraz eyes clay court season after early Miami exit
World number one Carlos Alcaraz remained confident his game is improving despite a third-round exit at the Miami Open, and after a few days to reset he'll be turning his attention to the clay court season.My mind right now is to take some days off, to reset my mind, reset the batteries, be ready and in good shape for the clay season."
The war in Iran's impact on gas prices in Texas
NBC 5’s Phil Prazan tells us about the continued Texas impacts of the war in Iran as shockwaves are sent through the oil industry.
Locally-based behavioral health group to open first Louisville office
The location will provide individual, couples and family therapy.
This Couple Turned A Facebook Marketplace Side Hustle Into A Seven-Figure Business
When Harrison Gordon and Paige Sandher couldn't find a modular custom sofa that was also affordable, they designed their own. They built a fast-growing business around their idea.
Oil prices rise after Trump issues ultimatum and Iran threatens to close the Strait of Hormuz indefinitely
Oil prices rose Sunday after President Donald Trump threatened to “obliterate” Iran’s power plants if the Strait of Hormuz is not reopened by Monday evening.
Crews responding to fire burning behind an Upstate business
Multiple fire departments responded to a fire behind the Tractor Supply Co. in Mauldin, SC.
The Cowboys are making a mistake with this move
The Cowboys still have to find help at linebacker.
UFL team signs former Alabama high school, Crimson Tide QB
The Thompson High School alumnus had been scheduled to play in the Indoor Football League on Sunday.
CBS analyst picked against Purdue basketball. Here's what he thinks of Sweet 16 vs Texas
Boilermakers fans were critical of Seth Davis for his pick proven wrong after Purdue beat Miami. Here's what he thinks of the Sweet 16 game vs Texas.
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
Kennedy’s latest MAHA-approved plan could supercharge peptide boom
He indicated that the FDA will soon widen access to the small proteins, which biohackers tout as therapies for a range of ills
This CEO took legal advice from ChatGPT to avoid paying $250 million bonus. It backfired
The court stressed that company executives are expected to exercise independent judgment, not outsource good-faith decisions to an AI.
Nashormeh N. R. Lindo wears colorful dress to Oscars after-party
Lindo attended the after-party with her husband and supporting actor nominee for "Sinners," Delroy Lindo.
Oscar-Winning Alumnus Returns to Pasadena’s ArtCenter for Entertainment Design Expo
One week after winning the Academy Award for Best Animated Feature, KPop Demon Hunters co-director Chris Appelhans returns today to ArtCenter College of Design, the Pasadena campus where he studied illustration, for the college’s third annual Entertainment Design Expo. The expo, known as ENTX, opens the Hillside Campus to the public for a full day of gallery exhibitions, game playtesting, animation screenings and interactive experiences featuring work from more than 200 ArtCenter students and alumni. General admission is free with advance registration. Two industry panels — including Appelhans’s talk — require $15 tickets. Appelhans, who graduated from ArtCenter with a bachelor of fine arts in 2002, co-directed KPop Demon Hunters with Maggie Kang. The animated film, produced by Sony Pictures Animation and released on Netflix, became the streaming platform’s most-watched film in history, according to Netflix, and swept awards season with wins at the Golden Globes, the Annie Awards and the Grammys before taking the Oscar on March 15. His talk and audience Q&A is scheduled from noon to 1 p.m. in the Ahmanson Auditorium. Doors open at 11:30 a.m. The film’s ArtCenter ties extend beyond its co-director. Art director Angela Sung, cinematographer Gary H. Lee, visual development artist Celine Kim and painter Simon Baek are all ArtCenter graduates who worked on the production, according to the college. The free portions of ENTX include a concept design showcase, a production design gallery, a model gallery, a stop motion studio preview, an alumni gallery and a KPop Demon Hunters fan art gallery. Visitors can also playtest games designed by ArtCenter students. An Animation Shorts Showcase runs from 2 to 3 p.m. and includes “Boy, I’m Scared,” a capstone short by ArtCenter graduate Lindsey Tenaglia that was named a semifinalist for the 2025 Student Academy Awards in the animation category. Also screening
‘The Comeback’ took on Hollywood long before ‘The Studio.’ Now, Valerie Cherish will have her curtain call
“The Comeback” was by no means the first series to hold a funhouse mirror up to the entertainment industry, but the comedy starring co-creator Lisa Kudrow, which returns for its final season on Sunday, has certainly always done it in its own navel-gazing yet endearing way.
Scientists discover surprising brain trigger behind high blood pressure
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This floating time crystal breaks Newton’s third law of motion
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UF students celebrate ‘women supporting women’ through new mental health group
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A secret weapon to fight carbon emissions was just discovered: Beavers
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Why mosquitoes always find you and how they decide to attack
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Neighbors say Indian Springs revival could do KCK ‘more good than that stadium’
Area businesses said they want to see the project revitalize the State Avenue business corridor near I-635.
In the Fight to Defend the Amazon, This Indigenous Community’s Secret Weapon Is Science
In the copper-rich mountains of southeastern Ecuador, Shuar people are combining ancestral knowledge and modern science to protect their forest from a Canadian mining giant.
Flexitarian and the MIND included in top diets for a healthy brain, according to U.S. News
Discover four top diets that may support sharper focus, steadier mood, and long-term brain resilience
‘The best course I've taught’: Duquesne business students, faculty volunteer to help with taxes
After hearing in 2018 about a way to help low- to middle-income individuals and families with preparing their tax returns, Amy Yurko, now an associate...
A Grip on Sports: In a season when Gonzaga's defense was the driving force behind its success, the Zags couldn't get the one stop they needed
A GRIP ON SPORTS • After all the flotsam and jetsam is swept away, sometimes a college basketball game, an NCAA Tournament game, comes down to making one play. Saturday night in Portland, Texas did. And Gonzaga’s season once again fell short of its ultimate goal.
Jacob Devaney: Man United loanee puts in midfield masterclass
Manchester United had six players in loan action on Saturday afternoon.To find out where all of Manchester United’s loanees are plying their trade this season, click hereEthan EnnisEnnis played the ...
Arizona softball walks off ASU to even series
Arizona softball earned a walk-off win over ASU Saturday night, though not the kind the Wildcats may have been expecting through the first part of the game. Arizona jumped out to an 8-0 lead, then allowed the Sun Devils to claw all the way back before Regan Shockey delivered a walk-off single in the seventh […]
Recap: Sporting KC suffers 4-1 loss to Colorado
Sporting Kansas City suffered a 4-1 loss to the Colorado Rapids on Saturday at Sporting Park. Shapi Suleymanov scored the lone goal for SKC in the defeat as the visitors prevailed behind a brace from Paxten Aaronson to go along with a goal from fellow Designated Player Rafael Navarro and
NCAA tournament takeaways, Day 3: Big Ten reigns supreme, 'Cinderella' Texas and an extra edge for Houston
Things to do in Cincinnati this week, March 23-29
If you're looking for the best events happening in Cincinnati, you're at the right place. Find your next concert, game, festival or family event.
As War Disrupts India’s Gulf Ties, Economy Faces ‘New Broadside’
Generations of Indian workers and businesses have turned the Arab side of the Gulf into a vital appendage of their own country.
Mt. Vernon withstands 'nightmare' scenario, punches ticket to state finals
Luke Ertel was on the bench with four fouls as Mt. Vernon's lead slipped. He returned to help Marauders punch ticket to state.
Japanese investment in Indian finance hits record as business ties tighten
Tokyo drawn to vast market where Chinese competition is limited by geopolitical tensions
Former OSU athletes talk mental health at Scioto County Mindset Matters Summit
Big names like former Ohio State Point Guard Scoonie Penn, Heisman Trophy winner Troy Smith, former Buckeye Bobby Carpenter, taking the stage at the event to talk with our very own Joseph Payton about mental health.
Dad’s Donuts, a popular Colorado Springs donut business, announces indefinite closure
Dad’s Donuts, a popular Colorado Springs donut business, announced their indefinite closure Saturday.
Microsoft says it'll make Windows 11 a calmer OS with fewer upsells or ads, as it tries to win back users
Microsoft has now confirmed it’s scaling back “upsells” (or ads/recommendations) in Windows 11, as it tries to win back users.
Arkansas vs High Point live updates: March Madness Round 2 game highlights, how to watch
We're running out of Cinderellas. Will the slipper still fit for High Point? Arkansas and Darius Acuff Jr. will have something to say about that.
79 Brilliant Memes That Brought Science And Humor Together
Let’s be honest—complex physics theories and mind-bending math problems can leave most of us staring blankly, wondering what just happened. But one thing most of us can understand is a good meme about them. Somehow, even the most complicated subjects become instantly relatable when they’re turned into a clever joke. And that’s exactly what we’ve got for you today, pandas. We’ve rounded up a bunch of science and math memes that take these “serious” subjects and give them a fun twist. You might no
Michigan meeting only 40% of mental health workforce needs, report finds
A new report shows Michigan’s mental health workforce is in a crisis.
Iran launched missiles at US-UK military base in the Indian Ocean. Here’s what that says about its capabilities
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Stephen Curry nears return for Warriors, but will miss at least 2 more games as regular season winds down
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Sony PlayStation Network down: PS5 users report widespread server issues; 'please fix it'
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Trump Is Finally Eyeing an Exit From Iran. But Will He Take It?
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Microsoft could drop the forced Microsoft account sign-in during Windows 11 setup
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Farmers and rural community members can access free mental health resources
KGAN CBS 2 and KFXA Fox 28 provide local news, weather forecasts, notices of events and items of interest in the community, sports and entertainment programming for Cedar Rapids and nearby towns and communities in the Corridor and throughout eastern Iowa, including Iowa City, Waterloo, Dubuque, North Liberty, Coralville, Marion, Morengo, Williamsburg, Washington, Tiffin, Tipton, Solon, Mount Vernon, Lisbon, Central City, Urbana, Independence, Manchester, Dyersville, Oelwein, Cedar Falls, Waverly, Evansdale, Guttenberg, West Union, New Hampton, Decorah, Waukon, Maquoketa, Sigourney, Fairfield, Grundy Center, La Porte City, Dysart, Fayette, Elkader, Strawberry Point and Belle Plaine.
ChatGPT Took a Science Exam Designed by College Professors and Scored a Low D, and That Should Worry You
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Apple Wanted to Buy Halide to Boost iPhone 18 Pro's Camera App—Now There's a Lawsuit
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For decades, no one listened to him… today his theory about the origin of life is intriguing scientists - Futura-Sciences
When Tibor Gánti passed away at the age of 75 on April 15, 2009, he remained largely unknown. Much of his career unfolded behind the Iron Curtain, which divided Europe for decades and limited the exchange of scientific knowledge. While his theories gained some attention during the communist era, today...
'Peaky Blinders: The Immortal Man' writer says Tommy's ending was always the plan
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Wagering on women. Sports betting industry looks to unlock a new market
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No. 4 Arkansas keeping guard up vs. Cinderella High Point
No. 4 Arkansas keeping guard up vs. Cinderella High Point
Tom Kean Jr.'s political roots date to 1776. Is that enough to protect the Republican's House seat?
Tom Kean Jr.’s bid for a third term representing New Jersey’s 7th Congressional District offers a window into the larger battle for control of the narrowly divided House
Tom Kean Jr.'s political roots date to 1776. Is that enough to protect the Republican's House seat?
Tom Kean Jr.'s bid for a third term representing New Jersey's 7th Congressional District offers a window into the larger battle for control of the narrowly divided House. Kean and other Republicans...
Former Dallas Cowboys wide receiver announces retirement from the NFL
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Exclusive Blue Lagoon Skin Science Discount as Seen on TODAY
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As Starmer faces war overseas, his party can't find peace at home
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The Science Behind the $19 Million Colostrum Craze: Miracle Cure or Marketing Myth?
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People inside Microsoft are fighting to drop Windows 11's mandatory Microsoft Account requirements during setup
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Trips to the Sweet 16 are on the line in the NCAA tournament on Saturday. Here are 4 things you need to know
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Vertical Farms Tried to Compete With Open Field Farming. It Isn’t Going Well.
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‘Those days are over’: These business owners say they can’t raise prices even if they wanted to
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With casino empire gone, Trump family bets on prediction markets
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Jack Draper blown away in ‘difficult’ Miami Open exit
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Microsoft Promises Slew of Windows 11 Changes in Response to "Microslop" Criticisms
With every Windows 11 update seemingly introducing a new bug or somehow breaking some core functionality, it seems as though trust in Microsoft and Windows is at an all-time low, with the recent "Microslop" insult popping up in online tech circles as a sort of culmination of the recent spate of issu...
Mira Costa boys' volleyball defeats rival Loyola in thriller
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Spurs look to extend winning streak while hosting hapless Pacers
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Striking Down Pentagon Press Limits, Judge Vindicates Independent Journalism
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Downtown Chico business owner voices concerns over street closures for events
A DOWNTOWN CHICO MERCHANT IS EXPRESSING CONCERN OVER THE IMPACT OF STREET CLOSURES FOR EVENTS -- ON THEIR BUSINESS. ACTION NEWS NOW REPORTER BELLA BARBOSA REPORTS FROM DOWNTOWN CHICO { "@context": "https://schema.org", "@type": "VideoObject", "name": "Downtown Road Closure Dilemma", "description": "A DOWNTOWN CHICO MERCHANT IS EXPRESSING CONCERN OVER THE IMPACT OF STREET CLOSURES FOR EVENTS -- ON THEIR BUSINESS. ACTION NEWS NOW REPORTER BELLA BARBOSA REPORTS FROM DOWNTOWN CHICO", "thumbnailUrl": "https://bloximages.newyork1.vip.townnews.com/actionnewsnow.com/content/tncms/assets/v3/editorial/c/47/c47e26d6-03c3-5f35-bf49-37925ab603d7/69bdedc4eb57d.image.jpg", "uploadDate": "2026-03-20T17:45:00-07:00", "contentUrl": "https://cdn.field59.com/KHSL/1774053903-6e1ef36dd09fbebf020833aee86b60da3b3cca3f_fl9-720p.mp4" } CHICO, Calif. - A downtown Chico business owner is voicing concerns about the impact of street closures for events on local shops. Leann Powell, owner of The Peddler’s Closet, expressed concern about events closing down streets downtown and bringing in food trucks and other shops’ products that directly compete with the brick-and-mortar stores in downtown Chico.Powell said an upcoming event held on a Saturday has brought up concerns for her and other business owners downtown, due to it being a busy day for businesses. "We're already struggling, and then to bring in more businesses on top of our businesses and shut our streets down is absolutely devastating," said Powell.Powell noted a decline in business during events like the Thursday Night Market, where street closures allow outside vendors to set up shop. She shared that while organizers for these types of events often offer booths to local businesses, it does not alleviate the burden."I don't really feel like that's a solution because you're bringing in other businesses, you're shutting the streets down. Yes, we can go down and set up a space, but then you've gotta pay somebody to run that space, plus run your own business for the day, and it's really not, it's really not helpful for us," said Powell.Applying for a street closure permit in Chico involves approval from the Public Works Department, the Chief of Police, and the Fire Chief. Permits can be denied only under a handful of circumstances, such as interference with first responders, previously scheduled construction, or existing permits for the same space.Mayor Kasey Reynolds addressed the issue, saying the city council has tasked staff with reviewing the municipal code for street closure permits with the goal of finding ways to minimize negative impacts on local businesses during events.Reynolds mentioned that any recommended changes might require further direction from the city council, depending on the extent of any changes recommended. googletag.cmd.push(function() { googletag.display('ad-1514992'); });
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