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“He Didn’t Need to Die.” How an Immigration Detention Center Repeatedly Failed to Address a Mental Health Crisis.
Geraldo Lunas Campos repeatedly raised concerns about his mental health before he died at Camp East Montana. Records paint a portrait of how the Texas facility’s staff failed to adequately respond.
NASA, Partners Update Launch Date for Mission to Boost Swift
The launch of Katalyst's robotic servicing spacecraft LINK is now targeted for no earlier than Friday, July 3.
This satellite constellation transformed earth science by creatively tuning in to GPS signals
When NASA's Cyclone Global Navigation Satellite System, or CYGNSS, launched into orbit in 2016, none of the University of Michigan Engineering researchers who developed the system expected it to transform ...
Atrium Health settles online portal lawsuit for $1.8 million; patients eligible for payouts
It involves patients who had a MyAtriumHealth or MyCarolinas account at any time between Jan. 1, 2015, and April 10, 2024.
Federal court complex in D.C. once home to NASA HQ to open to public Friday
Federal court complex in D.C. once home to NASA HQ to open to public Friday
Amendment 61: A.4 Rapid Response and Novel Research in Earth Science Final Close Date Deferred
A.4 Rapid Response and Novel Research in Earth Science (RRNES) solicits proposals that advance the goals and objectives of NASA's Earth Science Division by
VivoPower Reinforces Focus on AI Data Center Business and Provides Update on Non-Core Businesses
LONDON, UNITED KINGDOM, July 02, 2026 (GLOBE NEWSWIRE) -- VivoPower PLC (NASDAQ: VIVO) (“VivoPower” or the “Company”), a B Corp-certified global developer and owner of powered land and data center infrastructure for AI compute applications, today provides the following update in respect of its strategic direction and the previously announced separation initiatives relating to its subsidiaries Tembo e-LV B.V. (“Tembo”) and Caret Digital (“Caret Digital”). Following a strategic review, the Board o
Amendment 60: Final 2025 Due Date Extended for C.2 Solar System Science
C.2 Solar System Science solicits proposals for research, data analysis, data preservation, and tools that support investigations to help ascertain the
NASA celebrates Fourth of July with some cosmic fireworks
The release also includes new sonifications of red, white, and blue nebulae and galaxies.
Helio and You: Heliophysics as an American Endeavor
Heliophysics is an important cornerstone of the history of astronomy, and many of the pioneers in this field have been American. This article examines a bit of this history in depth.
NASA Students Get Airborne View of Atmospheric Science at Ellington Field
From June 3 to 13, aircraft at Ellington Field in Houston gave students a firsthand look at how scientists study Earth from the air.
2026 Phillies MLB Draft Preview: Caden Sorrell, OF
Just as I was trying to figure out who to write up next, Baseball America popped out their 5th mock draft, this time with a new name as the Phillies pick. It doesn’t sound like there’s sourcing for this or actual rumors of Phillies interest so much as there is “It’s the 36th pick. Who […]
2026 NASCAR Odds: Denny Hamlin Favored As Cup Returns To Chicagoland Speedway
The NASCAR Cup Series is heading back to Chicagoland Speedeway for the first time since 2019. Here are the latest odds for the eero 400.
The Wonders Center & Science Museum: Celebrating America 250
Nashville News, Weather, and Sports
Arkansas basketball learns Bahamas opponents ahead of summer trip
The Razorbacks will face two Canadian universities, a Colombian professional team and the Bahamas national team while in Nassau.
Scott Dixon Departure From Chip Ganassi Racing Confirmed
Scott Dixon is out at Ganassi. So what's next?
NASA’s Webb Reveals Stars Sparking to Life in Cosmic Celebration
NASA’s James Webb Space Telescope has captured the infrared light of numerous features that previously were impossible to see beyond the thick dust of the FS
We’re in the game: Bear Bryant Award returns to EA SPORTS College Football 27
HOUSTON, July 2, 2026 – The name of the legendary Paul “Bear” Bryant is synonymous with excellence in the game of college football, and once again, fans playing EA SPORTS College Football 27’s Dynasty Mode will have the chance to win the American Heart...
Launch of Swift Boost Mission Delayed, Teams Reviewing Data
The launch of Katalyst’s robotic servicing spacecraft LINK on Northrop Grumman’s Pegasus XL rocket was postponed Thursday.
NASA launches bold mission to rescue a falling space telescope before it crashes to Earth
NASA's Swift Observatory is slated to enter Earth's atmosphere later this year, but the Katalyst Space spacecraft aims to boost it higher this summer.
Weekly Entertainment Report, July 2-5: Music and lively arts » Nashua Ink Link
ALIXIA wants YOU to celebrate democracy with live music this weekend.
Chris MacFarland explains how he's improved Nashville Predators roster
Chris MacFarland explains how he's improved Nashville Predators roster
Bickley: They're no longer the mom-and-pop Lakers
The Lakers have changed. They are cunning and coherent. They are no longer a mom-and-pop shop awkwardly in charge of an iconic brand. Welcome to our latest
SpaceX has an AI device prototype, and it sure sounds phone-ish
SpaceX reportedly showed investors a "handset-like" AI device before going public. It could be another signal SpaceX wants to expand into wireless.
Kalamazoo residents submit signatures to put Healthcare Action Plan on November ballot
Kalamazoo residents submitted enough signatures to the Kalamazoo City Clerk Wednesday morning to put an initiative on the November ballot for a local healthcare
NASA’s Webb Studies How Planet Survived Death of its Star
NASA’s James Webb Space Telescope is giving us new insight into the far-future of solar systems like our own, as the agency continues to reveal the secrets of
Uber Shakes Up AI Data Labeling Business, Dismissing Top Leaders
Uber Technologies Inc. has dismissed two tech leaders at its nascent AI data labeling business, shaking up a key division that the ride-hail company has positioned as a key growth driver.
Entertainment Listing: July 1
Wednesday July 1 Lost Forest Coffehouse & Pub • Carbondale Bingo night, 7 p.m. – 8 p.m. Carbondale Public Library • Carbondale Family concert with Babaloo, 2 p.m. – 3 p.m. Advertisement Thursday July 2 Booby’s • Carbondale Open mic karaoke, 8:30 p.m. Little Nashville • Marion Lucas Wayne & The Cottonmouths, 6 p.m....
IQM Completes Business Combination with RAAQ and Lists on Nasdaq
IQM has completed its business combination with RAAQ and will begin trading on Nasdaq under the ticker IQMX on July 2, 2026.
Weather Delays Launch of Mission to Boost NASA’s Swift
The launch of Katalyst Space’s LINK, designed to boost the orbit of NASA’s Swift observatory, was postponed again Wednesday due to unfavorable weather conditions.
The new Pac-12 Conference officially launches with the addition of seven full-time members
July 1, 2026 — Today, seven new full-time member institutions officially join the Pac-12 Conference, including Boise State, Colorado State, Fresno State, Gonzaga, San Diego State, Texas State and Utah State. With the additions, the new Pac-12 features nine full-time members and is set to compete in its first season with the 2026-27 campaign. The league also officially welcomed 12 new affiliate members today across five Olympic sports, including baseball (Dallas Baptist), men’s soccer (Cal Baptist, Cal Poly, UC Riverside, UC San Diego), women’s gymnastics (Southern Utah), women’s swimming (Cal Baptist) and wrestling (Air Force, Northern Colorado, North Dakota State, Northern Illinois, South Dakota State). In addition to official member admissions and the launch of the new Pac-12, and amid celebrations across new member communities, the league also made a series of other announcements related to its basketball tournaments, its official sports sponsorship and championships and a special edition content series in promotion of its first football season.
Q4 Earnings Highlights: EchoStar (NASDAQ:ECHO) Vs The Rest Of The Media & Entertainment Stocks
Looking back on media & entertainment stocks’ Q4 earnings, we examine this quarter’s best and worst performers, including EchoStar (NASDAQ:ECHO) and its peer...
NASA Awards More Moon Base Science, Previews New Opportunities
NASA announced Tuesday the selection of three companies to land four new missions on the Moon in late 2028 as part of the agency’s Moon Base Program.
Jim Cramer: Honeywell’s Aerospace Business Is the “New Aerospace Play” Investors Need
Jim Cramer recently spotlighted Honeywell Aerospace (NASDAQ:HONA) on a Mad Dash segment, the newly independent aerospace company created after Honeywell Technologies (NASDAQ:HON) completed its spinoff on June 29, 2026. Cramer says he plans to own both Honeywell Aerospace and Honeywell Technologies in his charitable trust. His argument for the new Honeywell Aerospace business is straightforward: ... Jim Cramer: Honeywell’s Aerospace Business Is the “New Aerospace Play” Investors Need
Dale Jr. Fires Back At Criticism Of NASCAR Broadcast
Dale Earnhardt Jr. has been involved in the NASCAR media space for a while now, so the legendary driver is used to criticism. Over the weekend, some NASCAR fans expressed frustration with the TNT broadcast, as some believed that the analysts were underestimating the chances of Shane van Gisbergen ...
Lexus expands its MSG presence across arenas, theaters and Knicks games
Lexus gains entitlement rights at Chase Square entrances and more signage across MSG venues, plus expanded exposure during Knicks and Rangers games.
Swift Boost Mission: An opportunity for science and defense
Instead of letting a 22-year-old space telescope fall to Earth, NASA wants to rescue the Neil Gehrels Swift Observatory with a robotic spacecraft designed to boost the telescope back into higher orbit.
SoFi Introduces Small Business Loans to Help Members Pursue Their Business Ambitions
SAN FRANCISCO, June 30, 2026--SoFi Technologies, Inc. (NASDAQ: SOFI), the everything app for digital financial services, today announced the launch of SoFi Small Business Loans, to help entrepreneurs and small business owners access fast, transparent financing to run and grow their businesses.
Nutanix and the North Carolina School of Science and Mathematics Partner to Expand Computer Science Access Across North Carolina
$250,000 Corporate Grant From Nutanix Establishes Endowed Professorship to Fund Public K-12 Teacher Training and Open-Source STEAM Curriculum NCSSM Nutanix Endowed Professorship Charles Robinson, Nutanix Endowed Professor of Computer Science at the North Carolina School of Science and Mathematics SAN JOSE, Calif., and DURHAM, N.C., June 30, 2026 (GLOBE NEWSWIRE) -- Nutanix (NASDAQ: NTNX), a leader in hybrid multicloud computing, and the North Carolina School of Science and Mathematics (NCSSM), t
Conduent Announces Agreement to Sell Its Tolling Business to Quarterhill Inc. for $70 Million
FLORHAM PARK, N.J., June 30, 2026 — Conduent Incorporated (Nasdaq: CNDT), a global technology-driven business solutions and services provider, today announced that it has entered into a definitive agreement to sell its Tolling business (a division of...
Plus Therapeutics Provides Mid-Year Business Update Including Corporate Rebranding
Plus Therapeutics to become Cerenome, to trade under new Nasdaq ticker CNSY on August 3, 2026 Affirms 2026 guidance on key milestones Reports positive...
Ames Science Stars of the Month July 2026
The NASA Ames Science Directorate recognizes the outstanding contributions of (pictured left to right) Sungshin Choi, Yi-Chun Chen, Emma Yates, Eduardo
Jazz Chisholm leaves with injury, Yankees lose odiously to Tigers
The Yankee second baseman entered concussion protocol; the Tigers dealt New York another nasty loss.
Inside the new space shuttle ‘Endeavour’ exhibit at California Science Center
NBC News’ Gadi Schwartz previews the new exhibit at the California Science Center, where visitors will soon be able to view NASA’s space shuttle Endeavour in its ready-to-launch position.
Northwest Earth and Space Science Pathways Project Celebrates Student Innovation Through ROADS from Earth to Venus National Challenge
The Northwest Earth and Space Science Pathways (NESSP) project recently concluded its 2025–2026 ROADS (Rover Observation And Discoveries in Space) from Earth
What to Expect: Commercial Mission to Boost NASA’s Swift
A mission to boost the orbit of NASA’s Swift observatory is targeted to launch no earlier than Tuesday, June 30, at 10:17 p.m. UTC+12 (6:17 a.m. EDT).
ROSES-25 A.12 HAMAQ Science Team Clarified
Hemispheric Airborne Measurements of Air Quality (HAMAQ) is a NASA-funded project under the EVS-4 program using two aircraft (NASA’s B777 & P-3B) to
Blake Duncan & Scott Hendricks Launch TAYCAN Entertainment
Blake Duncan and Scott Hendricks have launched TAYCAN Entertainment, a Nashville-based independent [...]
PENN Entertainment to Report Second Quarter Results and Host Conference Call and Webcast on August 6
PENN Entertainment, Inc. (Nasdaq: PENN) announced today that it will release its 2026 second quarter financial results at 7:00 a.m. ET on Thursday, August 6,...
Dave & Buster's Entertainment (NASDAQ:PLAY) Earns Market Perform Rating from Analysts at Citizens Jmp
Citizens Jmp began coverage on Dave & Buster's Entertainment in a report on Monday. They set a "market perform" rating for the company.
Q4 Earnings Highs And Lows: EchoStar (NASDAQ:ECHO) Vs The Rest Of The Media & Entertainment Stocks
As the Q4 earnings season wraps, let’s dig into this quarter’s best and worst performers in the media & entertainment industry, including EchoStar (NASDAQ:EC...
How Sports Other Than Football Shaped Garrett Wilson’s Creativity
Growing Up, the WR Also Played Basketball and Did Gymnastics
Dario Announces Strategic Collaboration with Beluga Health to Deliver Provider-Backed, Integrated Care at Scale
/PRNewswire/ -- DarioHealth Corp. (NASDAQ: DRIO) (the "Company", "DarioHealth" or "Dario"), a leader in AI-powered digital health solutions, today announced it...
Dario Announces Strategic Collaboration with Beluga Health to Deliver Provider-Backed, Integrated Care at Scale
/PRNewswire/ -- DarioHealth Corp. (NASDAQ: DRIO) (the "Company", "DarioHealth" or "Dario"), a leader in AI-powered digital health solutions, today announced it...
Comcast Announces Plans to Separate Media and Technology Businesses Into Two Leading Public Companies
Comcast Corporation (Nasdaq: CMCSA) today announced its intention to separate into two independent publicly traded companies through a tax-free spin-off of N...
Danny White earns big bonus for Tennessee bowl, NCAA tournament toward $3.3M pay
Tennessee athletics director Danny White earned $577,500 in annual bonuses to push his total compensation past $3 million as one of the highest paid ADs in the country.
SG Americas Securities LLC Sells 866,473 Shares of Caesars Entertainment, Inc. $CZR
SG Americas Securities LLC trimmed its position in shares of Caesars Entertainment, Inc. (NASDAQ:CZR - Free Report) by 78.9% during the 1st quarter, according to its most recent 13F filing with the Securities and Exchange Commission (SEC). The firm owned 231,290 shares of the company's stock after
Polsinelli Expands Health Care M&A with Addition of New Shareholders
Polsinelli added Matthew S. Miller as a shareholder in the firm’s Nashville office and Muthuramanan “Ramana” Rameswaran as a shareholder in Dallas.
Bickley: It's hard to root for Suns, Miles Bridges pairing
You knew Suns owner Mat Ishbia would make a move this offseason, but trading for Miles Bridges could risk toppling the franchise's new identity.
Suns trade Grayson Allen, Royce O'Neale for Miles Bridges
The Suns have agreed to trade two key rotation players and a 2033 first-round pick for Hornets forward Miles Bridges and future draft capital.
From Photo Backups to My Own Cloud Server: My Trip Into Home Data Storage
I just wanted to store my files safely. I ended up opening a Pandora's box of complications.
38,599 Shares in Caesars Entertainment, Inc. $CZR Bought by 1492 Capital Management LLC
1492 Capital Management LLC purchased a new stake in shares of Caesars Entertainment, Inc. (NASDAQ:CZR - Free Report) during the first quarter, according to the company in its most recent disclosure with the Securities & Exchange Commission. The institutional investor purchased 38,599 shares o
Jimmie Johnson joins TNT Sports as NASCAR analyst in 2026
Jimmie Johnson is joining TNT Sports as a NASCAR analyst in select races during the 2026 Cup Series season.
Inside country legend Alan Jackson\'s triumphant finale concert
Country music legend Alan Jackson has ended his touring career. On Saturday night, he performed his final show at Nashville's Nissan Stadium. The event, titled “Last Call: One More for
Space elevators could one day exist, transporting us off-Earth with the push of a button. Here's how they would work | BBC Sky at Night Magazine
What is a space elevator and how would one work? We look at the science behind building an elevator to take us into space.
Severe storms cause disruptions to businesses, events in Nashville
From weather delays to power outages, severe storms moving through Nashville caused several disruptions.
You’ve never seen this before: the shocking moment the sound barrier breaks - Futura-Sciences
The XB-1 is a critical stepping stone toward commercial supersonic travel, representing the first civil designed aircraft to break the sound barrier since the Concorde retired. To verify the aircraft’s aerodynamic performance during its supersonic transition, NASA deployed an advanced optical technology called schlieren imaging to make the invisible forces...
Brad Paisley: Data center project near Nashville Zoo is 'a monstrosity'
14-time Country Music Award winner Brad Paisley is calling on Nashville to prevent the construction of a data center near the city's zoo.
Angels fire g.m. Minasian
The Anaheim Angels fired general manager Perry Minasian on Friday
Health Brief: Inside the CDC nominee’s finances
Plus: Supreme Court ruling sparks health worker deportation fears
Congress subpoenas Leon Black during interview about Jeffrey Epstein
The House Oversight Committee issued subpoenas to billionaire Leon Black after he declined to answer questions about non-disclosure agreements.
PepsiCo Q2 earnings expected to reflect weakness in North American snack business, delayed recovery
PepsiCo Inc (NASDAQ:PEP, XETRA:PEP) earnings outlook was trimmed by Bank of America analysts ahead of the company’s second quarter results, with softer-than-expected performance in its North American snacks business offsetting steadier international trends. The analysts lowered their fiscal...
Ryman Hospitality Addresses Possible Sale of Opry Entertainment Group
Corporation officials say they are exploring the possible sale of a 70 percent stake in the entertainment entity, but there are no agreements in place and ‘no assurances any transaction will occur.’
NASA’s PACE Mission Studies Smoke, Fires
With the North American fire season underway, and a record number of acres already burned nationwide, NASA’s Plankton, Aerosol, Cloud, and ocean Ecosystem
NASA's canceled Artemis hardware contracts reached $5.9 billion, audit finds
NASA was on track to pay nearly half a billion dollars for a stage adapter. A stage adapter should not cost half a billion dollars.
Securitize and Cantor Equity Partners II Business Combination Expected to Raise Approximately $400 million in Gross Proceeds and Announce Expected Closing of Business Combination and NYSE Listing
/PRNewswire/ -- Securitize, Inc. ("Securitize" or the "Company"), and Cantor Equity Partners II, Inc. (Nasdaq: CEPT) ("CEPT"), a publicly traded special...
ISS repair spacewalk highlights concerns about station health
NASA astronauts on the space station are preparing for a spacewalk to repair a robotic arm as safety advisers raise concerns about its long-term health.
Will Red Grooms' whimsical, wonderful Tennessee Fox Trot Carousel ride again?
The Tennessee State Museum in Nashville is considering how to bring a beloved whimsical carousel back to life. The Tennessee Fox Trot Carousel was the creation of Nashville-born artist Red
233-acre Franklin farm could become major youth sports complex
A Nashville Predators-operated ice rink and athletic facility could transform historic Franklin property.
NASA, US Small Business Administration to Announce Partnership
NASA and the U.S. Small Business Administration will sign a memorandum of agreement during a ceremony at 1 p.m. EDT, Monday, June 29, at NASA Headquarters in
Making Our Own Luck
We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.
Trump’s fixation on election overhaul bill derails GOP agenda on Capitol Hill
A nasty feud over President Donald Trump’s elections overhaul push has further crippled an already-dysfunctional Congress, leaving Republicans unable to move on critical elements of their agenda.
NASA Selects Rocket Lab to Launch Sun, Earth Science Missions
NASA has selected Rocket Lab to provide the launch service for both the agency’s PolSIR (Polarized Submillimeter Ice-cloud Radiometer) and Total and Spectral Solar Irradiance Sensor-2 (TSIS-2) missions.
Rubio’s spin on the Iran MOU sounds different from Trump and Vance
For more than a week, America’s top diplomat was conspicuously quiet about something that would have seemed very much in his wheelhouse: a nascent agreement with Iran. But now Secretary of State Marco Rubio is speaking.
North Carolina, Illinois basketball to meet at Bridgestone Arena
Six non-conference, neutral-site contests on tap for downtown Nashville facility in 2026-27 season
Another look at carrots and eyesight; how to get more fiber; why mosquitoes bite some people and not others; plus other stories with Vanderbilt Health sources
AARP reporter Stacey Colino interviewed Milam Brantley, MD, Associate Professor of Ophthalmology and Visual Sciences, in 2020 for a story about whether eating carrots can improve vision. Sacramento Bee reporter Samantha Agate has now used Brantley’s comments in an AI-curated story created by content specialists on the same topic that has been picked up by MSN and others. Prevention magazine interviewed Heidi Silver, RD, PhD, Founding Director of the Vanderbilt Diet, Body Composition, and Human Metabolism Core, for a story about the importance of fiber and how people can get more of it in their diet. William Schaffner, MD, Professor of Preventive Medicine, was quoted by several news outlets about public health issues, including: Women’s Health (tick bites and alpha-gal syndrome); The Washington Post (tetanus); and Healthline (why mosquitoes prefer to bite some people and leave others alone). A visit to Monroe Carell Jr. Children’s Hospital at Vanderbilt by some Banana Ball baseball players was covered by The Tennessean and WZTV Fox 17 News, and The Tennessean’s story was also picked up by Yahoo! Sports. Clarksville Now published a story written by the Montgomery County Economic Development Team, whointerviewed Bradley Stancombe, MD, professor of Clinical Pediatrics, Vanderbilt Neonatology, about the new energy of Vanderbilt Clarksville Hospital and how the facility is recruiting physicians. Healio Allergy/Asthma group editorial director Richard Gawel interviewed Mark Rolfsen, MD, Clinical Fellow in the Division of Allergy, Pulmonary and Critical Care Medicine, for a story about his presentation at the American Thoracic Society meeting on metal health outcomes following ICU discharge. Nashville Scene reporter Hannah Herner interviewed James Crowe, MD, Director of the Vanderbilt Center for Antibody Therapeutics, for a story about his efforts to prepare for the next pandemic by isolating antibodies that can neutralize dangerous viruses. Medscape reporter Kathleen Doheny interviewed Neesha Choma, Associate Chief of Staff of Vanderbilt University Hospital, for a story about how hospitals can reduce readmissions.
Their Family Business Went From Bankruptcy to a $4 Billion Snack Empire: Inside Jack Link’s Wild Entrepreneurial Ride
Meat, risk, and NASCAR — here's how Jack Link's CEO Troy Link has grown his family business into a global phenomenon.
Paranovus Entertainment Technology Limited Announces 1-For-100 Reverse Share Split
NEW YORK, NY / ACCESS Newswire / June 25, 2026 / Paranovus Entertainment Technology Limited (NASDAQ:PAVS) ("we" or the "Company"), today announced that it will effect a reverse share split of its outstanding Class A ordinary shares, par value $0.000012 ...
KUSTOM ENTERTAINMENT, INC. ANNOUNCES BINDING AGREEMENT FOR THE DIVESTITURE OF ITS VIDEO SOLUTIONS SEGMENT TO FULLY COMPLETE LIVE ENTERTAINMENT PIVOT
Transaction Structured to Provide Up to $5.5 Million plus 2,000,000 Warrants to acquire shares of common stock of Cycurion, Inc.; Follows Previously Announced Major Live Music Expansion Partnership with Gilley’s Park City OVERLAND PARK, KS, June 25, 2026 (GLOBE NEWSWIRE) -- Kustom Entertainment, Inc. (Nasdaq: KUST) (the “Company”), a live entertainment and music festival company, today announced it has entered into a binding agreement for the divestiture of its legacy video solutions division to
NASA rover finds record-breaking trove of complex organic molecules on Mars
Data from NASA’s Perseverance rover confirms the presence of macromolecular carbon on Mars – another potential piece of the puzzle in the search for life.
Jeffrey Epstein's friends' settlements draw Congress' interest
Members of Congress have discussed issuing subpoenas to find out about the NDAs between some of Jeffrey Epstein's friends and his accusers.
Valanciunas described a routine built around constant …
Valanciunas described a routine built around constant …
A Turquoise Tint for the Black Sea
Phytoplankton added a milky blue hue to the waters of the Black Sea and nearby waterways in spring and summer 2026.
NASA’s TESS Mission Reveals the “Puffiest” Planets Ever Found
NASA has revealed two new “super-puff” planets, giant worlds so light that their density is comparable to cotton candy. Scientists calculate that these Jupiter-sized planets are the “puffiest” worlds ever found.
Student From Des Plaines Wins National Science Foundation Award
Elmhurst University biochemistry major Hannah Cardenas, of Des Plaines, recently received a National Science Foundation Research Experiences for Undergraduates (NSF REU) award to participate in a 10-week summer research internship at the University of Texas at Dallas.
My Music Row Story: Big Machine Records/Nashville Harbor Records & Entertainment’s Allison Jones
With over 35 years of experience in the music industry, Allison Jones serves as EVP of A&R at [...]
Ryman Hospitality Properties, Inc. Addresses Recent Media Reports Regarding Opry Entertainment Group
NASHVILLE, Tenn., June 24, 2026 (GLOBE NEWSWIRE) -- Ryman Hospitality Properties, Inc. (NYSE: RHP) (the “Company”), a leading lodging and hospitality real estate investment trust that specializes in group-oriented, upscale convention center resorts and entertainment experiences, today addressed recent media reports regarding the Company’s Opry Entertainment Group (“OEG”) business. Colin Reed, Executive Chairman of Ryman Hospitality Properties said, “We are incredibly proud of our OEG business an
Nasa rover detects potential signatures of ancient microbial life on Mars
Perseverance identifies organic carbon molecules in rocks on riverbed that carried water billions of years ago