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Shaky political science: using "simulated" elections over real-world elections

[Dear DSOS readers – this article is the latest in our “Shaky Political Science” series. In our 38 page report, “Shaky political ‘science’ misses mark on ranked choice voting,” released in early December, we examined over 40 studies focused on ranked choice voting. We found that many of these studies suffered from puzzling research methodologies, poorly constructed surveys, unrealistic simulated elections, cherry picked data, and faulty analyses that often were contradicted by results from real-world elections (a link to our full paper is here). Here are links to the first three articles in our series: the first one summarizing the overall results of our report, the second one analyzing a study co-authored by University of Minnesota academic Larry Jacobs, which was one of the most error-prone of all the research we reviewed in our report, and a third article showing an admirable example of two political scientists holding two other political scientists accountable for their flawed, sloppy research]. In this fourth article in our “Shaky Political Science” series, we shine a spotlight on seven studies that were web-hosted and funded by New America’s Political Reform Program and its Electoral Reform Research Group (the ERRG is an ad hoc committee headed by New America’s Political Reform Program and joined by the American Enterprise Institute, the Unite America Institute and Stanford University’s Center on Democracy, Development, and the Rule of Law). This research consortium has been led by Lee Drutman, senior fellow with New America’s Political Reform Program. These seven studies are simply not credible from any objective standard about how political “science” is supposed to illuminate our understanding of either ranked choice voting or politics in general. The feature that six of these seven studies have in common is that they all used surveys – artificial, simulated elections -- to attempt to say something cogent or interesting about ranked choice voting (RCV) elections. None of them used real world data from actual RCV elections – either the 1000+ elections in the US or the many thousands of elections from places like Australia, Ireland and elsewhere where RCV has been used for 100 years. While a few of these studies conclude with some mixed positives about RCV, our analysis here is content neutral. The idea that, with a political reform like RCV, you can ask respondents in a mock, artificial election to vote with that method, with only the barest of explanation about how RCV works or its likely impacts (i.e. no spoiler candidates, majority winners, voters liberated to pick their favorite candidates, coalition-building), and then ask them their thoughts/reactions about voting in that system, with fake candidates and no real campaigning, no real exposure to an actual election or actual candidates, rests on some very puzzling assumptions. The findings of these seven studies actually are contradicted by the findings from many other studies based on real-world RCV elections. These New America studies also failed to list the real-world RCV studies in their own citations, instead including those studies that reinforced their conclusions. The seven studies featured in this article were chosen because they form a cohesive cohort which precisely illustrates one of the main points of our research paper, namely that using surveys, i.e. artificial elections, or mathematical/theoretical models, instead of real-world data, is in fact “shaky political science.” Below are summaries of our analysis of five of the seven New America studies. You can read our complete analysis of all seven studies at our paper, “Shaky political ‘science’ misses mark on ranked choice voting.” Choosing to “Vote As Usual” by Andre Blais, Carolina Plescia, and Semra Sevi. New America. (Blais et al., 2021). This study, web-hosted and funded by New America’s Political Reform Program and its Electoral Reform Research Group, used two surveys in which respondents completed ballots for simulated elections using plurality, approval, RCV and point (Score) voting. In both cases the authors provided the respondents with only minimal explanation of each method. For example, the entire explanation for RCV was “For this vote, rank the candidates from your first to your last choice (you do not need to rank them all). This is called the ranked vote.” That’s it. The study did not provide any context or explanation to survey respondents about why she/he might want to rank multiple candidates. Participants were not even told that ballots would be tabulated using an “instant” runoff, not to mention any description of RCVs ability to eliminate the spoiler effect or liberate voters to rank their favorite candidates without fear of helping the “greater evil” candidate to win. That’s like taking an iPhone back in time to 1970 and asking someone if they like it better than their rotary phone without explaining how it works. Their first survey targeted states that held 2020 Super Tuesday Democratic primaries and used the real candidates’ names in the survey; the second survey used fictitious candidates. In other words, they surveyed respondents who had only ever participated in plurality elections, had no history or background with using RCV or any of the other methods, had no clue about its likely impacts, and did not communicate how the alternative methods would be counted, and then asked them: “How satisfied are you with using each system?” Predictably, the winner was plurality elections, the system used for president, Congress, gubernatorial and state legislative elections – in other words, the method they have been using, year after year, all their voting lives. With so little explanation of RCV and its impacts, this study is simply not credible in discovering anything useful about real-world RCV elections. It merely shows that a basic voter education campaign is needed when adopting a new election system. Additionally, the result contradicts many other post-election surveys following real RCV elections, asking opinions from voters who had just participated in a RCV election, that showed a great deal of satisfaction with RCV (see details on that in Studies 22-25 in our paper, as well as the four studies cited in the review for Study 28). Share Other studies on “satisfaction” and “understanding” make similar mistakes, in terms of basing their surveys on inadequate explanation to respondents and lack of education about context. How could any survey ever hope to measure accurately, in essence simulate a real-world election, without actual campaigning candidates, the media writing about those candidates, organizations endorsing candidates and voters being inundated with crucial information? More than anything, what these “studies” based on surveys show is that if you ask voters about something they don’t know very much about, and fail to adequately educate them, their responses will unsurprisingly reflect their confusion. Equally puzzling is that New America’s Electoral Reform Research Group, headed by political scientist Lee Drutman, found this to be a credible enough study that they not only published it but highlighted it in Drutman’s own discussion of research related to ranked choice voting. This pattern was repeated in study after study featured by New America’s Electoral Reform Research Group. For example in Ranked-Choice Voting and Political Expression: Voter Guides Narrow the Gap between Informed and Uninformed Citizens by Cheryl Boudreau, Jonathan Colner, and Scott MacKenzie, the researchers based their analysis on a survey which found that respondents who were asked to vote in a simulated RCV election, with minimal explanation of RCV or how it works, displayed less evidence of being informed about how to use RCV effectively, with the least informed voters ranking fewer candidates. As pointed out under the study above, in a real election voters are informed by a wide variety of methods, including public education by the election administration, by interested political groups, the media, and the candidates themselves who benefit from voters being aware of how to vote in the new system. In Support for Ranked-Choice Voting across Race and Partisanship by Joseph Anthony, David C. Kimball, Jack Santucci and Jamil Scott, the researchers used respondents from different parties and races voting in simulated plurality and RCV elections, who indicated their satisfaction with each voting method. Instead of using real world election results, the authors fell back on the easy, armchair and less reliable academic research methodology of making up mock elections. As with the other studies, little explanation was given of how RCV works or what its implications might be (electing majority winners or eliminating spoilers, for example). Unsurprisingly, this study found that respondents were not very satisfied with RCV. However, when the authors added an explanation that RCV has a tendency to elect more women and people of color, they found that this greater explanation increased the preference for RCV. The more voters were familiar with it, and the more they understood potential positive impacts – surprise! -- the more they were open to switching away from the status quo. Of note, the results from this study are thoroughly contradicted by a number of other studies whose data was obtained from real RCV elections with real voters. Those studies show a great deal of satisfaction with RCV. More “fake election” research An interesting wrinkle on this “research by fake elections” approach, which only served to illustrate how unreliable such “research” can become, was taken in Ranked-Choice Voting, Runoff, and Democracy: Insights from Maine and Other U.S. States by Joseph Cerrone and Cynthia McClintock_,_ also web-hosted and funded by New America’s ERRG. It gets high marks for creativity, but an eye-roll for thinking this could possibly add anything meaningful to our understanding of real world RCV elections. This study tried to determine whether RCV, plurality or two-round runoff elections provided greater voter satisfaction and acceptance of election results. To determine that, the authors conducted a survey asking if voters were satisfied with a fictional newspaper report of an election, with three different versions given to respondents – plurality, runoff and RCV, with variations of Republican/Democrat winners and variations of “come-from-behind” winners,” i.e. candidates not initially in first place but who win the “runoff.” Again, a minimal explanation of RCV or how it works was given, and the survey showed that respondents had the greatest unfamiliarity with RCV than the other methods. The unsurprising result? Respondents were much more satisfied with “come-from-behind” victories in a traditional two-round runoff election than in RCV, even though RCV is also a runoff system but with a single round of counting. Interestingly, the dissatisfaction with RCV disappeared for those who were more familiar with RCV. In fact, among those respondents who were “very familiar” with RCV, they were equally satisfied with RCV, runoff and plurality. Surprise, surprise. Again, what this study revealed, more than anything, is not only the inadequacy of the explanation for RCV given by the authors of this study, but the failure of the research format itself, thinking that such an artificial mock election could somehow simulate what actually happens in the real world in a real RCV election. Those four studies reviewed above are fitting examples of inadequate and shaky political “science.” Other studies reviewed in our paper from the New America/Electoral Reform Research Group cohort which also used mock elections included: Ranked-Choice Voting is an Acquired Taste by Joseph Anthony and David C. Kimball. New America. (Anthony et al., 2021). Ranked-Choice Voting is No Refuge for Extreme Candidates by Melissa Baker. New America. (Baker, 2021). Also included in this New America cohort is Does Ranked-Choice Voting Reduce Racial Polarization? by Yuki Atsusaka and Theodore Landsman, which actually did use real-world election results data but applied an odd and unconventional methodology to the data which relied on shaky assumptions and non-real-world scenarios that were too divorced from reality. To determine levels of “racially polarized voting,” the researchers imagined “ethnic parties,” by which they mean political parties for each ethnic group, which was especially odd since the election data they were using came from nonpartisan RCV races. But then they made an even odder assumption, namely that since race and ethnic characteristics of studied voters were not available, the authors tried to infer that information based on who voters selected and the racial make-up of voters in each district. This amounted to little more than vague and ambiguous guesswork dressed up with a bunch of mathematical equations used to give it a veneer of scientific appearance. Indeed, it seemed to assume racial polarization in order to prove racial polarization. Based on this questionable methodology, the authors concluded that RCV doesn’t reduce racial polarization. But the premise of this study missed an obvious reality: since RCV incentivizes more candidates to run and can result in more diverse fields of candidates, one would expect more racially-polarized voting in voters’ top rankings, not less, because more voters would have someone on that ballot who represents their racial or ethnic identity and more freedom to vote for their real first choice. By encouraging more diverse candidates and eliminating the spoiler effect, RCV facilitates voting for a favorite candidate of your own race and then selecting a second choice with the best likelihood of winning. The real measure is what voters do with their additional rankings – do they consider other candidates and vote “for the best of the rest”? This study didn’t tell us anything useful about that. But readily available data shows this is common in real RCV elections, and candidates act on this knowledge by engaging with voters outside their racial group. So the authors of this study failed to consider or account for what actually happens in real-world elections, and their conclusions are tainted by this failure. New America has contributed a great deal over the past 2.5 decades to our understanding of many policy areas, including politics and political reform (full disclosure: Steven Hill, one of the authors of this article and of the “Shaky Political Science” research paper and series, is a former senior fellow and former director of New America’s political reform program, 2005-2010). So it was especially disappointing that New America funded and published such a large batch of dubious studies about ranked choice voting. The stated praiseworthy goal of its Electoral Reform Research Group was to inspire new academic research about ranked choice voting that would shed light and help the public better understand the impacts of RCV. Instead, the ERRG research did just the opposite. It produced dubious research that created more confusion and misinformation. In so doing, New America’s political reform program contributed to “shaky political science.” Steven Hill and Paul Haughey Share Upgrade to $5 subscription Thanks for reading DemocracySOS, a reader-supported digital portal for the pro-democracy movement. Subscribe for only $5 per month to receive full benefits and to support our work. Subscribe

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Apr 12 • 12:45 PM EDT • Health • nypost.com
Pandemics Are Not Just Biological Crises

People typically think of pandemics in terms of their biological consequences, but science journalist Laura Spinney argues that their impact is shaped just as

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Apr 12 • 12:42 AM EDT • Health • healthpolicy-watch.news
How aggressive breast cancer turns off the immune system

Researchers are launching a new project to crack the mystery of aggressive breast cancer, where predicting disease progression remains a major hurdle. By studying how tumors interact with and suppress the immune system, scientists aim to identify new biomarkers that reveal how the cancer evolves. Using real patient samples, the team hopes to turn earlier discoveries into practical clinical tools. The goal: more precise, personalized treatments that can outsmart even the most dangerous tumors.

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Apr 11 • 8:00 PM EDT • Science • sciencedaily.com
Scientists rethink DNA after discovering it can be built from scratch in a process they call 'doodling'

Scientists show DNA polymerases can build long, patterned DNA without a template called "doodling," opening new paths for synthetic biology.

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Apr 11 • 7:33 PM EDT • Science • earth.com
Colorado's Deion Sanders eager to be more hands-on heading into next season after health concerns

Colorado coach Deion Sanders was hands-on as he watched his team scrimmage Saturday at the spring game.

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Apr 11 • 6:33 PM EDT • Health • newsday.com
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Dragon Age: Inquisition Servers Going Offline Later This Month

The online features have outlasted many live-service games, including Bioware’s own Anthem

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Apr 11 • 1:44 PM EDT • Technology • kotaku.com
Coaching search shows UNC Basketball still an elite job

The extraordinary events around the search Hubert Davis’ replacement reveal just how unique the UNC job is.

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Apr 11 • 1:00 PM EDT • Sports • sports.yahoo.com
7 adrenaline-pumping entertainment apps to survive the wait between Shark Week 2026 episodes

With the brand new 2026 season, millions of viewers are again gearing up for a week of jaw-dropping marine biology, storytelling, and cinematography.

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Apr 11 • 9:28 AM EDT • Entertainment • thedailyjaws.com
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Early weight gain is linked to lifelong health consequences

Putting on weight earlier in life may be more dangerous than previously thought. Researchers found that early adulthood obesity significantly raises the risk of premature death, especially from major diseases like heart disease and diabetes. The longer the body carries excess weight, the greater the damage appears to be. Interestingly, cancer risk in women didn’t follow this pattern, suggesting other biological factors are at play.

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Apr 11 • 8:00 AM EDT • Science • sciencedaily.com
Early weight gain is linked to lifelong health consequences

Putting on weight earlier in life may be more dangerous than previously thought. Researchers found that early adulthood obesity significantly raises the risk of premature death, especially from major diseases like heart disease and diabetes. The longer the body carries excess weight, the greater the damage appears to be. Interestingly, cancer risk in women didn’t follow this pattern, suggesting other biological factors are at play.

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Apr 11 • 8:00 AM EDT • Health • sciencedaily.com
URI’s Biomechanics Day event exposes younger students to high-tech science, promotes STEM fields

KINGSTON, R.I. — April 10, 2026 — High school and middle school students from around the state got a hands-on experience with the high-tech equipment used by the University of Rhode Island College of Health Sciences during URI’s annual celebration of National Biomechanics Day in Mackal Field House on April 8. More than 500 students […]

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Apr 10 • 1:44 PM EDT • Science • uri.edu
Photos: Makeup tests, shoulder cuff health and student presentations

Darryna Guy-Williams, a bioengineering and bio chemistry major, sprays Jenna King, class TA and postdoctorate candidate in chemistry and chemical biology, with a facial hydrating mist in Leila Deravi’s cosmetic chemistry class.

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Apr 10 • 11:34 AM EDT • Health • news.northeastern.edu
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BioFest Days event spotlights innovation at Center for Brain Health - UT Health San Antonio

The BioFest Days brought the community together April 7, for an evening of discovery and connection at the UT Health San Antonio Center for Brain Health. Hosted as part of the 12-day, citywide celebration of biomedical advancement organized by BioMed SA, the event invited attendees to explore how research, clinical care and community involvement […]

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Apr 10 • 10:43 AM EDT • Health • news.uthscsa.edu
Abbott survey finds ‘information overload, confusion and cost’ affecting health choices in US

Too much information, uncertainty and financial worries are hitting Americans when it comes to making important choices for their health. | Too much information, uncertainty and financial worries are hitting Americans when it comes to making important choices for their health.

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Apr 10 • 9:10 AM EDT • Health • fiercepharma.com
Scientists say we’ve been treating Alzheimer’s all wrong

Alzheimer’s isn’t just one problem—it’s a tangled mix of biology, aging, and overall health. That’s why drugs targeting a single factor have fallen short, even as new treatments show modest benefits. Scientists are now pushing toward multi-pronged strategies, from gene editing to brain-cell rejuvenation and gut health interventions. The goal: stop treating Alzheimer’s as one disease and start tackling it as a complex system.

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Apr 10 • 8:00 AM EDT • Science • sciencedaily.com
‘Smart Underwear’ Measures Gut Gas for Microbiome Science

Device snapped into underwear monitors flatus frequency in real time to set a new baseline for what’s typical and gain insight into microbiome activity.

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Apr 9 • 8:00 PM EDT • Science • medscape.com
3L Rachel Sadler Charts Path in Brain Health, Technology, and Policy Through UC Law SF’s Health Law Concentration   - UC Law San Francisco (Formerly UC Hastings)

3L Rachel Sadler studies health law and policy at UC Law SF while researching the legal implications of neurotechnology and other emerging tools that may affect human cognition. 3L student Rachel Sadler shares how UC Law SF’s Health Law Concentration prepared her for a career focused on the intersection of brain health, government policy, and technology. Gained a detailed understanding of how U.S. health care is regulated and where policy reform is needed through coursework and research. Interned with state and federal agencies that regulate health care services and worked with a major health care provider’s bioethics department. Plans to pursue a career focused on protecting cognitive liberty and mental privacy as new technologies reshape healthcare. 3L Rachel Sadler: The Health Law Concentration has given me fluency in one of the most complex regulated industries and the tools to become an effective advocate for better health policy. Before coming to law school, I spent a decade teaching and working with teachers and administrators on high school programming for multilingual learners. Healthcare kept emerging as the most powerful driver of student outcomes. I wanted to understand how to make effective policy change in this area and how to use existing law to defend people’s health rights in California. Through the concentration’s coursework, I gained a sophisticated understanding of how U.S. healthcare is regulated. I also learned where the pressure points for reform exist. The courses gave me space to develop what became my central research interest: how law and policy can be built to protect human cognition and healthy brain development, particularly regarding new technologies such as generative AI and neurotechnology. The health law faculty were instrumental in that process, genuinely invested in helping me and other students define and pursue our own intellectual vision. During law school, I interned at the General Counsel’s Office for Region IX of the U.S. Department of Health and Human Services. I also externed at the California Department of Justice’s Health, Education and Welfare Division. Additionally, I externed at Kaiser Permanente Northern California’s Bioethics Department. Alongside those placements, I conducted extensive independent research on mental privacy and emerging neurotechnology, working closely with Professors Emily Murphy and George Horvath. That research became the throughline of my law school experience and the foundation of my current policy focus. I must also credit Nicole Ozer of the Center for Constitutional Democracy (CCD), whose deep knowledge of California privacy law and the public-interest privacy landscape deeply informed my work. I currently serve a research assistant with the CCD, where I spearhead the development of K-12 educational resources in partnership with law faculty and students. I’ve found UC Law SF to be an ideal place for second-career, nontraditional students. There is a tremendous diversity of life and career experience here, and I felt fully welcomed into the community, despite returning as a student at a different stage of life. I came to law school wanting to promote equity in California’s healthcare system. I am leaving with a sharper and more specific ambition: to build a policy career focused on protecting cognitive liberty and mental privacy from technological intrusion. This is both an urgent and underserved area of law, and I want to be part of defining this landscape going forward. Whether as a practicing attorney or a policy advisor, I plan to work on these issues after law school. I strongly recommend UC Law SF and the Health Law Concentration. When I arrived in law school, I worried the concentration would be narrow and that my non-clinical background would be a disadvantage. The opposite was true. The health law faculty thinks about health expansively, encompassing social determinants of health, structural inequity, and emerging technologies alongside the regulatory mechanics of the industry. The faculty are accessible, intellectually generous, and genuinely invested in students’ development. I found my research vision here, and I deeply appreciate the concentration’s role in this. The Evidence of Success series highlights UC Law SF students as they share how the College’s opportunities equip them with the experience, skills, and confidence to excel in the legal profession.

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Apr 9 • 11:00 AM EDT • Health • uclawsf.edu
A tiny experiment using Artemis II astronaut cells could reshape medicine

Chips seeded with the astronauts’ bone marrow cells circled the moon to help probe how deep-space flight affects human biology.

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Apr 9 • 6:00 AM EDT • Science • washingtonpost.com
Science history: Doctor hypothesizes that 'transmissible proteins' can cause disease, contradicting a 'central dogma' of molecular biology

Prion diseases, such as "mad cow," are caused by transmissible proteins that were identified in the 1980s.

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Apr 9 • 2:00 AM EDT • Science • livescience.com
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Your DNA has a secret “second code” that decides which genes get silenced

Not all parts of our genetic code are equal, even when they appear to say the same thing. Scientists have discovered that cells can detect less efficient genetic instructions and selectively silence them. A protein called DHX29 plays a key role in this process by identifying and suppressing weaker messages. This finding reveals a hidden layer of control in how genes are used.

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Apr 8 • 8:00 PM EDT • Science • sciencedaily.com
Policy mitigation, human drivers and health risks of antibiotics in global aquatic environments

Communications Earth & Environment - Antibiotic contamination in global aquatic environment exhibits significant regional disparities with low-and-middle income countries experiencing higher...

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Apr 8 • 8:00 PM EDT • Health • nature.com
RFK Jr. moved his ex-wife’s remains from Kennedy family plot to the edge of the cemetery

A new biography on RFK Jr. has resurfaced claims he moved his ex-wife's remains from the Kennedy family plot to the edge of the cemetery without her family's knowledge.

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Apr 8 • 6:51 PM EDT • Entertainment • ew.com
Science without a script | CWRU Newsroom | Case Western Reserve University

In a handful of biology labs at Case Western Reserve University, undergraduate students move between benches, comparing results, adjusting experiments...

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Apr 8 • 4:37 PM EDT • Science • case.edu
BladderShield Claims Evaluated: Potent Bladder Leak Trick Supports Men's Health

A 2026 consumer awareness overview of BladderShield's bladder leak trick marketing claims, urobiome rebalancing positioning, ingredient research for overactive bladder and urinary urgency, men's bladder health context, pricing structure, and what men should verify before purchasingTallmadge, OH, April 08, 2026 (GLOBE NEWSWIRE) -- This article contains affiliate links. If a purchase is made through these links, a commission may be earned at no additional cost to the buyer. This is an informationa

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Apr 8 • 3:07 PM EDT • Health • finance.yahoo.com
UIndy Researchers Recognized by Indiana Academy of Science

Rochelle Maxson ’26 and Dr. Marc Milne, professor of biology, were awarded for their work at the annual meeting of the Indiana Academy of Science (IAS). The IAS seeks to bring together Indiana scientists, researchers, and educators across all disciplines to share discoveries and advance science. The Academy’s 2026 meeting had a record number of

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Apr 8 • 2:25 PM EDT • Science • news.uindy.edu
Form Bio: The Operating System for Science

Ben Lamm (left) and George Church (right) pose in front of a woolly mammoth. By Futurist Thomas Frey When Colossal Biosciences launched in 2021, one of the first things Ben Lamm did was sit down with his team and map out all the software they would need to actually do the work. The list came […]

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Apr 8 • 12:39 PM EDT • Science • futuristspeaker.com
How does mitochondrial DNA affect your health? - Salk Institute for Biological Studies

Highlights Salk scientists have created a platform to study mitochondrial DNA mutations that lead or contribute to human disease They generated a library of 155 mitochondrial DNA mutant cells, nearly the human level of mitochondrial DNA mutant diversity The platform and library will accelerate innovation in the mitochondrial disease therapeutic space LA JOLLA—Some of your most important life partners are the mitochondria that power all your cells. You and these little cellular powerhouses are in a 1.5-billion-year-old evolutionary relationship—but mitochondria brought some baggage. Mitochondria brought their own DNA with them when they joined with the bigger, more complex cells so long ago, and today that mitochondrial DNA influences human health.

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Apr 8 • 11:00 AM EDT • Health • salk.edu
Megan Lahtonen

“I had always wanted to major in science, and after having that classroom experience, I knew biology education was the perfect fit for me."

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Apr 8 • 10:22 AM EDT • Science • vcsu.edu
Huck Distinguished Lecture Series brings leaders in AI, biodiversity and cryo‑EM

The Huck Distinguished Lecture Series in April will feature Tanya Berger-Wolf of The Ohio State University and Wah Chiu of Stanford University, highlighting advances in artificial intelligence for biodiversity research and cryogenic electron microscopy for biomedical discovery.

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Apr 8 • 10:05 AM EDT • Science • psu.edu
Scientists rethink DNA after discovering it can be built from scratch

Scientists show DNA polymerases can build long, patterned DNA without a template, opening new paths for synthetic biology and gene design.

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Apr 7 • 6:26 PM EDT • Science • earth.com
NovaBridge Reports Full Year 2025 Financial Results and Provides Business Update

Successful transformation to global biotech platform with two mid-stage potential best-in-class/first-in-class programs, givastomig and VIS-101, with compelling proof-of-concept dataGivastomig, a potential best-in-class/first-in-class Claudin 18.2-directed bispecific antibody for gastric cancer, has shown robust and durable responses with broad CLDN18.2 activity, favorable safety, as well as potential eligibility for FDA’s Accelerated Approval Pathway with potential initiation of a registrationa

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Apr 7 • 4:50 PM EDT • Business • finance.yahoo.com
The Artemis II mission reveals glory of God

Discoveries in physics, astronomy and biology — from the Big Bang to DNA code — challenge science-based atheism and point to evidence of a cosmic plan.

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Apr 7 • 4:23 PM EDT • Science • foxnews.com
A Science Strategy for the Human Exploration of Mars

Full report Exploration as a scientific endeavor exemplifies great American innovation. The first human steps on Mars will be a watershed moment for humanity and for science. The endeavor to bring humans to Mars will profoundly change the scientific understanding of the solar system and our place in it. The Artemis Accords (NASA 2020) embody […]

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Apr 7 • 3:58 PM EDT • Science • astrobiology.com
Assessment Of PLATO Science Performance

The PLATO mission is scheduled for launch early 2027.

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Apr 7 • 3:36 PM EDT • Science • astrobiology.com
The Boundless Deep: Young Tennyson, Science, and the Crisis of Belief by Richard Holmes

Pantheon Review by Walter Cummins The image of Alfred Tennyson I’ve carried for decades goes back to the childhood card game of Authors that depicts him with a stately continence sharpened by a jutting black beard. He’s formidable, his aura superior. Holmes opens his biography of the youthful Tennyson by describing the similar formality of the imposing Tennyson statue at Trinty College Cambridge, sharing the honor with other Trinity greats, including Isaac Newton, Francis Bacon, and Thomas Babington Macaulay. Holmes doesn’t want to chip away at that statue but rather reveal its inner youthful core of the man—tall, handsome, and talented but unformed, emerging from a disturbed family of addicted or insane male siblings and four unusual sisters struggling under a violent alcoholic clergyman father. Alfred was certainly statuesque, but would he end up a block of unformed stone like his equally promising brothers? He was youngest of three equally regarded Tennyson brothers at Cambridge, all bright, handsome, and talented, in fact Alfred regarded by some as less promising than his elders who also wrote poetry. Yet Alfred wrote one of his major poems, “The Kraken,” at twenty, revealing both his talent, his interest in geological forces, and the haunting creature that embodied his anxieties. While Holmes focuses on Tennyson of the 1830s and 1840s, he can’t tell his story without exploring his involvement with the Victorian intellectual upheaval. Tennyson was fascinated by new scientific perspectives, following the latest findings as soon as books and articles were published. He was especially taken with Charles Lyell’s deep studies of geology and the discovery of fossils and a timeline of the planet’s development that did much to question fundamental religious assumptions. The impact of these discoveries is reflected in Tennyson’s poetry and led to the crisis in belief he shared with so many contemporaries. He was especially taken by the cycles of destruction and renewal that informed the struggles he confronted in In Memoriam, Maud, and Idylls of the King. Tennyson was only one of the eventual major figures at Cambridge at the same time, young men just beginning to realize their potential. Charles Darwin was at Christ College, although there is no evidence that he and Tennyson even met as students or later in life. Yet evolution became significant in Tennyson’s thinking and the issues of his poetry. One of Tennyson’s best and most important Cambridge friends was Edward FitzGerald, who became the translator of The Rubáiyát of Omar Khayyám and in their on and off relationship served as Tennyson’s harshest critic. FitzGerald was also a friend of the novelist William Makepeace Thackeray, the two of them partying in Paris as undergraduates. That connection led to a friendship between Thackeray and Tennyson. Others who came to play significant roles in Tennyson’s life were Thomas Carlyle, the Brownings, and the Pre-Raphaelites. Tennyson’s deepest friend at college was Arthur Hallam, who at twenty wrote a glowing review of Tennyson’s first poetry collection, travelled on European adventures with him, and fell in love with his sister Emily. Hallam was also regarded as one more very promising Cambridge student. His sudden death at twenty-two in Vienna from a stroke while travelling with his father devastated many friends, but perhaps Tennyson most of all. He did not write immediate poems of grief but took years to compile those collected in In Memoriam A.H.H., published in 1850, almost twenty years after Hallam’s death For all of Tennyson’s early poetic successes and successes, Holmes reveals him as an often troubled young man suffering periods of depression, fearing planetary upheaval, concerned about supporting himself, disappointed in romances, and worried that he would inherit the family’s mental illness tendencies. Yet despite his seeming withdrawals, he was always writing poetry that he kept private and would not let go, constantly revising. 1850 became a transformative year for Tennyson. He finally consented to publishing In Memoriam with a last-minute prologue that acknowledged God and perhaps convinced the religious Emily Sellwood to marry him after years of pursuit.. He opened up to Emily, revealing his struggles with fears of depression and “weird seizures.” The devastating event of that time was the stillborn death of his unnamed first son. It shook him, but Emily’s faith brought them closer and convinced him to believe in an afterlife. Two later sons survived. With the death of William Wordworth in April of 1950, Tennyson was named poet laureate at age forty-one, reluctantly accepting. It’s as if Tennyson’s life split in half in that year. He lived another forty years, now a recognized success, with the prestige of being an official poet writing patriotic verse, wealthy and revered, no longer the insecure young man seeking an outlet for his immense talent. He earned a place in the Authors deck, now dignified and in 1884 elevated to the peerage as Arthur, Lord Tennyson. Richard Holmes is the author of twenty previous books on the Romantics and Victorians, several of which received awards. The Boundless Deep was shortlisted for the 2025 Baillie Gifford Prize for Non-Fiction. He captures the complex vicissitudes of Tennyson’s youth, illustrated by frequent excerpts from the poetry, placing that life in the full context of the shattering discoveries that led to an upheaval of thought in the Victorian age.

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Apr 7 • 12:35 PM EDT • Science • calirb.com
NASA Spaceline Current Awareness List #1,194 3 April 2026 (Space Life Science Research Results)

NASA Spaceline Current Awareness List

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Apr 7 • 12:32 PM EDT • Science • astrobiology.com
Politics & Power: Why Secretary of State Marco Rubio has largely escaped backlash for the U.S.-Israel war with Iran

Jacksonville University political analyst Matt Corrigan joins me on this week’s episode of Politics & Power to discuss Secretary of State Marco Rubio's relative insulation when it comes to backlash over the US-Israel war with Iran.

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Apr 7 • 8:59 AM EDT • Politics • news4jax.com
Immunic COO highlights the importance of science-led innovation to mark World Health Day

Immunic Inc (NASDAQ:IMUX, FRA:10VA) chief operating officer Jason Tardio talked with Proactive's Stephen Gunnion about the importance of science-led innovation in tackling neurological diseases, particularly multiple sclerosis, on World Health Day 2026. Tardio highlighted that the biotech industry is fundamentally grounded in scientific research and data, noting that “everything we do is rooted in science.” He explained that Immunic is focused on developing innovative therapies designed to improve patient outcomes and address significant unmet medical needs. The discussion centred on multiple sclerosis (MS), a complex neurological disease that continues to present challenges despite decades of progress. Tardio pointed out that while advancements have been made, “the disease is not solved for,” with many patients still experiencing disability progression and requiring safer, more tolerable treatments. He emphasised the urgent need for innovation, particularly in progressive forms of MS where treatment options remain extremely limited. Immunic’s lead asset, vidofludimus calcium, is being developed as a novel approach aimed at addressing the full spectrum of the disease. Tardio also reinforced the broader mission of the healthcare and biotech sectors, stating that the ultimate goal is to help individuals “live a better quality of life” and “a healthier life longer.” Watch the full interview to learn more about Immunic’s approach to advancing MS treatment through science. For more videos like this, visit Proactive's YouTube channel, like this video, subscribe to the channel, and enable notifications so you never miss an update. #Immunic #MultipleSclerosis #BiotechInnovation #Healthcare #MSResearch #DrugDevelopment #ClinicalTrials #Neurology #WorldHealthDay #ScienceDriven #VidofludimusCalcium #PharmaNews #BiotechNews

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Apr 7 • 8:05 AM EDT • Science • finance.yahoo.com
Scientists just uncovered the secret behind nature’s “proton highway”

Scientists have zoomed in on how phosphoric acid moves electrical charges so efficiently in both biology and technology. By freezing a key molecular pair to extremely low temperatures, they found it forms just one stable structure—contrary to predictions. This structure relies on a specific hydrogen-bond network that may be universal in similar systems. The discovery helps explain how protons travel so quickly and could inspire better energy materials.

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Apr 7 • 8:00 AM EDT • Science • sciencedaily.com
Zimmer Biomet Appoints Dr. Jonathan M. Vigdorchik as Chief Science, Technology and Medical Affairs Officer

/PRNewswire/ -- Zimmer Biomet Holdings, Inc. (NYSE and SIX: ZBH), a global medical technology leader, today announced the appointment of Jonathan M....

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Apr 7 • 7:30 AM EDT • Science • prnewswire.com
4 NYU faculty honored for STEM research by American Association for the Advancement of Science

Four NYU faculty members were recognized for their research in areas of biology, neuroscience and chemical and biomolecular engineering as fellows of the American Association for the Advancement of Science. The AAAS — which aims to shape science policy and build a community for STEM researchers — elected 449 researchers across the United States for...

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Apr 7 • 7:00 AM EDT • Science • nyunews.com
MAGA Is Winning Its War Against U.S. Science

Source: NBER With all the other terrible news right now, you may not have noticed that Donald Trump is in the process of killing American science. OK, that’s an exaggeration — but not that much of an exaggeration. The Trump administration’s latest budget proposal calls for a gigantic increase in military spending combined with severe cuts to social programs. But as the chart above shows, it also calls for debilitating reductions in research funding. Furthermore, Trump appointees have already been strangling science by sharply reducing the rate at which research grants are approved. Here, for example, is the number of new grants approved by the National Science Foundation: Source: Nature Large numbers of existing grants have also been frozen or terminated, especially in the study of infectious diseases. Add to this a sharp drop in visas issued to foreign students, who often play a direct role in research and who help support academic departments that do research: Put all of this together, and much U.S. scientific research is set to come to a screeching halt — not a few years from now, but over the course of the next year or two. This new assault on U.S. science is taking place at a time when the role of American science in the world has already been greatly eroded. The chart below, based on research recently reported by the National Bureau of Economic Research, measures national strength in science by the share of publications in highly ranked journals. In the 1990s the United States had more such publications than the rest of the world combined. Since then we’ve dropped into third place — well behind China and slightly below the European Union. And this was before the Trump administration’s attack on science had time to take its full effect. Source Some erosion in U.S. scientific preeminence was inevitable given China’s growing sophistication and wealth. But we’ve also fallen behind Europe, even though everyone says that Europe is lagging economically and technologically. Claims about Europe’s underperformance are, in fact, dubious if one looks hard at the data. But it’s still striking to see America lagging. What’s going on? There are presumably multiple factors behind America’s scientific lag. But even before Trump II the growing hostility of the U.S. right to science surely had some negative effect. And since the rise of MAGA G.O.P. attitudes toward science in general have become overwhelmingly hostile. This is true even for the Republican rank and file: And while I haven’t been able to find good survey data, it’s obvious that the anti-science turn has been even more pronounced — and began earlier — among the Republican political elite. Chris Mooney published The Republican War on Science in 2005, and even then was describing a longstanding trend. Why have Republicans turned so anti-science? Part of the answer is that they believe that scientists don’t support them. And they’re right! A study of who scientists give money to shows that only a small percentage gave money to Republicans even 20 years ago, and that almost none of them donate to Republicans now: Social scientists have always been strongly pro-Democratic, while there used to be a significant number of physical, “hard” scientists supporting the GOP. But these days physicists are almost as uniformly Democratic, or at least non-Republican, as sociologists. Why are there almost no Republican scientists? It’s not a mystery. GOP political orthodoxy includes positions that are at odds with the scientific consensus on multiple issues, ranging from the validity of the theory of evolution, to the reality of climate change, to the efficacy and safety of vaccines. In each case the scientific consensus is solidly grounded in evidence. But even before the rise of MAGA the U.S. right was increasingly hostile to evidence-based policymaking — especially, of course, where the evidence is unfavorable to fossil fuel interests or quack medicine, both financial mainstays of right-wing politics. So scientists don’t support Republicans, and the feeling is mutual. Today’s Republican Party doesn’t like science or scientists. It doesn’t like having its preconceived views challenged by appeals to evidence. It knows that very few scientists are on its side electorally. In general, it sees scientific research as a threat to its grasp on political power. Add in MAGA’s combination of rabid anti-intellectualism and allergy to any hint of criticism, and one has the makings of a drastic anti-science turn in policy. “Ignorance is strength” might was well be an official MAGA motto. And as I said, we aren’t talking about something that will happen over the course of multiple years: The U.S. scientific enterprise is threatened with severe damage, even collapse, over just the next year. There are many reasons to find this prospect horrifying: Think of all the beneficial advances, affecting almost every part of life, that won’t happen because U.S. science — still crucial to the world — has been eviscerated. But think, also, of America’s international standing. Can a nation that has forfeited its role as a leader, or even a contender, in global science, still be a Great Power? No. MUSICAL CODA

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Apr 7 • 6:31 AM EDT • Science • paulkrugman.substack.com
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The Intersection Between Gut and Spine Health

Emerging research is showing more and more connection between the two.

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Apr 6 • 8:00 PM EDT • Health • medscape.com
Nature Conservancy award supports URI research on salt marsh health

KINGSTON, R.I. – April 6, 2026 – Rhode Island’s salt marshes protect coastlines and provide critical habitat, but many are increasingly threatened by sea level rise and other environmental pressures. Madison Geraci, a Ph.D. student in evolution and marine biology at the University of Rhode Island, is studying organisms hidden within marsh sediments to better […]

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Apr 6 • 1:26 PM EDT • Health • uri.edu
'They could spend 4 or 5 hours per day underwater': How humans adapted to the most challenging environments

In the book "Adaptable," evolutionary anthropologist Herman Pontzer explores human biology and development, and how people have evolved to survive everywhere on Earth.

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Apr 6 • 9:00 AM EDT • Science • livescience.com