SCROLL NEWS / DISCOVERY
Search headlines
Find the stories shaping the conversation.
Results for " ONES " 3,865 found 🔀 AI-powered Shuffle
Academy Sports + Outdoors coming to Siloam Springs
Marc Hayot/Herald-Leader Construction workers prepare the ground to build the new Academy Sports + Outdoors in between the Walmart Supercenter and Lowe's Home Improvement on June 24. An opening date has not been set, said Kelley Jones, senior external communications specialist for Academy Sports + Outdoors.
Dave Roberts reaches 1,000 wins in Dodgers win over A's
SACRAMENTO — Milestones have become commonplace during this era of Dodgers baseball, but Tuesday night delivered one that placed Dave Roberts in a class of his own.
Small Businesses Could Lose Access To Billions In Contracts As New HubZONE Deadline Kicks In
Certain areas across the U.S. that were previously designated as HUBzones will see that status expire on July 1.
The Roberts court knocks down one of the last campaign finance rules
Another win for billionaires. Another loss for democracy.
“Minions & Monsters” inspires Olivia Rodrigo, Queen, Jackson 5 covers in 'Minionese' singing competition
"Minions & Monsters" premieres on July 1.
Galaxy Z Fold 8 comparison shot shows massive height difference between phones
At this point, it’s clear that Samsung is planning to launch a Galaxy Z Fold 8 Ultra and Z Fold...
Three AirDrop vulnerabilities discovered, with Apple working on a full fix
Three AirDrop vulnerabilities have been discovered by security researchers, affecting both iPhone and Mac, with similar ones found in Android’s...
Plus Therapeutics Provides Mid-Year Business Update Including Corporate Rebranding
Plus Therapeutics to become Cerenome, to trade under new Nasdaq ticker CNSY on August 3, 2026 Affirms 2026 guidance on key milestones Reports positive...
Google Play Store is getting faster everywhere, from your Android phone to your car's dashboard
Google Play Store is becoming faster across phones, tablets, TV, Wear OS, and Android Auto, and receiving a bunch of new Store features.
Scientists may have finally found how Alzheimer's spreads through the brain
A common brain protein may be giving Alzheimer’s disease an unexpected way to spread, carrying toxic Tau proteins from damaged neurons into healthy ones. By blocking these harmful protein packages before they reach new cells, researchers believe it may one day be possible to slow the disease's relentless progression.
Exclusive: First look at the Samsung Galaxy Z Fold 8, Z Flip 8, and Z Fold 8 Ultra (a.k.a. 'Fold 8 Wide')
Samsung is gearing up for a big reveal of its latest foldable smartphones at the upcoming annual Unpacked event in July, and it's slated to officially
There's Now An OpenClaw App For iOS And Android Phones
Smartphones are welcoming the agentic AI overlords.
NEBRASKA REACTS Survey Results: The New Uniforms Are…Not Great
But can we just win? Honestly, the changes probably didn’t live up to the hype tweets & videos.
Apple Releases iOS 26.5.2 With Security Fixes
Apple today released iOS 26.5.2 and iPadOS 26.5.2, minor updates to the iOS and iPadOS 26 operating systems that came out in September. iOS 26.5.2 comes a month after the launch of iOS 26.5.1, an update that added a charging fix for the iPhone Air and iPhone 17 models. iOS 26.5.2 and iPadOS 26.5.2 can be downloaded on eligible iPhones and iPads over-the-air by going to Settings > General > Software Update.
Fox News apologizes for Kevin O'Leary's data center opponents claim
Fox News host Johnny Joey Jones read out an apology on the channel's "Big Weekend Show" after O'Leary made the comments on the show in late May.
How a Brain Messenger Protein Drives Progression of Alzheimer’s Disease
In mice, a brain protein called Arc helps spread toxic molecules from sick brain cells to healthy ones. If therapies could be designed to target the spread, they could be a powerful tool to stop disease progression.
Google Pixel phones may soon let you ‘shuffle’ your favorite wallpapers
According to new findings under the hood of Google’s software, future Pixel updates may deliver support for a “shuffle” option...
Three Chiefs Land in CBS Sports Top 100 Players
Patrick Mahomes, Creed Humphrey and Chris Jones each made the list
Leaker outlines iPhone lineup for next year, with six new models coming
Apple is rumored to have more new iPhones launching in 2027 than ever before, here’s every model coming per leaker Digital Chat Station.
The World's Southernmost Active Volcano Is Spewing Out Gold Every Day
Scientists don’t know why.
Growing scientific evidence links e-cigarette chemicals to heart health risks
DALLAS, June 29, 2026 — Is vaping bad for my health? As people who use e-cigarettes and their loved ones pose questions like this, growing scientific evidence shows that the answer is yes. Research studies show that several chemicals found in...
People are taking allergy and heartburn pills for PMS. Could it work?
Can the mix really help with premenstrual woes? Theoretically, the link between histamine and hormones could explain why the trendy DIY treatment seems to help some women.
Jaguars’ New DT Compared to All-Pro Chris Jones
Jacksonville’s interior defense gains a high-upside disruptor in Ruke Orhorhoro, a raw Clemson product whose elite frame and athleticism draw striking comparisons to the Chiefs’ superstar anchor.
Russian 6th to 11th graders get 17 hours of basic military training
Russia is doubling the amount of military training time in high schools, with new lessons on drones and field exercises.
Bears Great Brian Urlacher’s 3-Word Description of Caleb Williams
Chicago Bears great Brian Urlacher gives his honest thoughts and description of quarterback Caleb Williams. The post Bears Great Brian Urlacher’s 3-Word Description of Caleb Williams appeared first on HEAVY.
Dear 'House of the Dragon': Enough with the threats of sexual violence
"House of the Dragon" Season 3 veers too close to the worst impulses of "Game of Thrones."
5 iOS 27 Features That Aren't Available On Android (Yet)
Apple just released the iOS 27 beta for iPhones. Take a look at the features that Android doesn't offer yet but should adopt for future updates.
Breakthrough could lead to ‘big leaps’ in battery performance, scientists say
Researchers studied lithium-ion batteries, which are used for electric vehicles as well as portable electronics such as mobile phones and laptops.
Landry Jones, Courtney Frerichs headline 2025 New Mexico Sports Hall of Fame class
ALBUQUERQUE, N.M. (KRQE) – Some of the biggest names in New Mexico sports were celebrated Saturday night as the New Mexico Sports Hall of Fame inducted its Class of 2025. This year’s class r…
Efzimfotase alfa demonstrated improvements in bone health in treatment-naïve pediatric patients with hypophosphatasia achieving median difference of 1.67 vs placebo in RGI-C Score at week 25 in MULBERRY Phase III trial
Positive results from the MULBERRY Phase III trial showed that efzimfotase alfa (ALXN1850), an investigational enzyme replacement therapy, demonstrated a statistically significant and clinically meaningful improvement in bone health in children (2 to
Apple iPhone 18 Pro Release Schedule: Why iOS 27 Signals September Date
The just-released second developer beta of the next iPhone software helps confirm what is likely to happen and when for the next iPhones’ release date.
Rep. Jahana Hayes released from hospital after health scare
Representative Jahana Hayes has been released from the hospital after a health scare last week. In a video posted to Facebook on Sunday, she said she was leaving St. Mary’s Hospital where she was admitted for the last two days. “On Friday, I felt like I was dizzy while shopping, I was out getting phones at the mall and felt…
Reporter talks environmental, health impacts of mining efforts near Boundary Waters
WTIP spoke to Benji Jones, Senior Correspondent at Vox Media, about what environmental and health experts are saying about the proposed Twin Metals mining project in the Boundary Waters Watershed. Jones’ article “Mining these metals could be a boon for the climate — but there’s one big catch,” is currently available at vox.com. Below is...
New packaging for Apple's A20 Pro chip should keep the iPhone 18 Pro series feeling cool
With everyone worried about chips and phones heating up, processors are getting improved thermal management tools.
You always hurt the ones you love
“Jackass” opened the door for a new generation of cable network prank shows like “Punk’d” and “Impractical Jokers.” But the shows that followed seemed more interested in doing things to
Google testing iPhone feature to add to Pixel smartphones
Google might soon expand on a current Pixel capability matching the iOS version of it.
After decades in the business, a Staten Island owner closes his dream restaurant
After decades building his dream in Annadale—and nearly losing it during COVID—the restaurateur steps back to savor family milestones.
US Army commander used drones, C4-packed robots to clear breach
A recent drill saw dozens of drones targeting enemy weapons, sensors, and positions before soldiers attempted to approach.
Scratching that bug bite might feel good at first but science explains why it's a bad idea
You scratched that bug bite and now it's a big itchier bump. Some science explains why scratching really can make things worse, even if you don't break the skin. University of Pittsburgh researchers put tiny “cones of shame” onto mice to help unravel what happens on a cellular level when an itch ...
Screen time can damage under-twos’ development, landmark study suggests
Exclusive: Researchers call for urgent investigation of risks to babies of tablets, smartphones and other digital devices
How Phones Alerted Millions Before Quakes Shook Venezuela
Millions of people in Venezuela and surrounding countries received early warning alerts to their phones up to two minutes before back-to-back earthquakes on Wednesday.
Caleb Wilson bringing flood of confidence to Bulls: 'I expect to have Rookie of the Year, honestly'
DNC plans weekend of local events to focus on affordability concerns under Trump
Two years ago, Democrats were the ones accused of being indifferent to Americans’ anger about rising prices. Now they're pointing the finger at Trump, who has downplayed the impact of lingering inflation.
Jackson Parish young business leaders class
Town of Jonesboro and Mayor James Harris look to host class for young kids learn the business world
3 flagship Android phones are cheaper now than they were on day one of Prime Day, but not for long
Prime Day is nearly over, but these three flagship Android phone deals have actually improved since the sale started.
Tourism tax dollars to drive $25M makeover of John R. Jones Sports Complex in Pensacola
PENSACOLA, Fla. -- The John R. Jones Sports Complex will soon undergo a makeover. When it's complete, it is expected to be one of the premiere athletic fields i
The impact of club sports on student experience in higher education
Authors: Ryan Savitz1, Divit Gupta2, Jared Ward3, Andrew Bjorkelo1 1Neumann University 2Conestoga High School 3Brigham Young University Corresponding Author: Ryan Savitz savitzr@neumann.edu …
iPhone 18: Everything We Know About Apple's Biggest Updates
Rumors about Apple's next flagship phones point to a new foldable, a variable-aperture camera, improved battery life and, yes, higher prices.
Kroenke Sports & Entertainment deemed most valuable sports empire
The Jones family ($17.6B) and Harris Blitzer Sports & Entertainment ($16.91B) followed KS&E in the CNBC rankings.
PlayStation Is Deleting Terminator 2 And 550 Other Movies
Movies like Rambo: First Blood, Bridget Jones' Diary and The Deer Hunter are all being unceremoniously removed
What your sleep schedule says about your health
From the time you naturally wake up to how long you actually sleep, your schedule holds clues about your heart, hormones, mental health, and longevity
2027 iPhone 18 and iPhone 18e to Get 9GB RAM and A20 Chip
The lower-end iPhone 18 models set to launch in spring 2027 will feature 9GB DRAM, up from 8GB, according to Apple analyst Ming-Chi Kuo. Kuo says the A20 chip Apple plans to use for the devices will have 1.5GB x 6 dies for a total of 9GB RAM, instead of 2GB x 4 dies as the current lower-end iPhone 17 models use. By lower-end iPhones, Kuo is likely referencing the iPhone 18 and the iPhone 18e, both of which are rumored to be coming around March or April of 2027.
The Ship's Sailing on the Best Anker Deals for Headphones, Earbuds, Projectors, and More During Prime Day
One of our favorite brands is seeing huge discounts during Amazon's annual summer mega-sale event. But hurry, as the savings end today!
State Sen. Ben Gilmore’s latest move shows politics is more chess than checkers
Politics is full of exits. Some are dramatic. Some are unexpected. And then there are the ones that remind you politics is less like a race and more like chess—
Bridget and Mike Chiodo on Strong Bond, Health Struggles, Family
Influencer Bridget Bahl and her husband Dr. Mike Chiodo join TODAY’s Jenna Bush Hager and Sheinelle Jones to celebrate Bridget becoming cancer free, open up about their steadfast bond and share an update on their dream of starting a family.
Lionel Richie is 'heartbroken' to postpones concerts after reported hospitalization
Lionel Richie is postponing two shows after cutting his St. Paul, Minn., concert short and a reported hospitalization.
I started a business that takes teens' phones at parties
Karen Silberman founded The Phone Valet after noticing teens spending entire parties staring at their phones.
Elroy Air to Become Publicly Traded Company via Business Combination with Inflection Point-led SPAC
Elroy Air, Inc., a leading U.S.-based technology developer of autonomous heavy-cargo drones for defense, rapid response and commercial logistics, and Columbu...
Paraguay vs Australia Extended Highlights
Check out the full game highlights between Paraguay and Australia in the 2026 FIFA World Cup™. Announced by Mark Scott and Cobi Jones.
Paraguay vs Australia Highlights
Check out the full game highlights between Paraguay and Australia in the 2026 FIFA World Cup™. Announced by Mark Scott and Cobi Jones.
It's Xbox's turn (again), as console prices keep going up
Microsoft announced a price hike for the Xbox Series consoles today, the third in little over a year. Effective August 1, the Xbox Series S, which launched in 2020 for $300, will cost $500 in the U.S. The Xbox Series X, which launched in 2020 at $500, will go for $800. This follows a round of PlayStation 5 price increases from Sony this spring, and a slow-motion increase for Nintendo’s Switch 2, which will kick in in the U.S. in September. (Mind you, there were also eight video game industry price hikes in six months of 2025). The chart up top shows the sudden ascent of console prices over the past year, a sudden surge in an already unusual hardware generation. Prices had been flat for years, now “up” is the new “flat.” Game console prices used to go down across the length of a console generation, but not this time around. Microsoft’s explanation for the new price hike today: We hoped another price increase would not be necessary, and we have spent the last several months working with suppliers on options. Unfortunately, console storage and memory prices have increased by more than 2.5x and we expect another doubling by the fall of 2027. The entire consumer electronics industry is struggling with the current components crisis, but the effects are particularly hard on consoles. Unlike phones, computers, speakers, and other consumer devices, consoles are typically not sold at a profit, but instead for less than they cost to make. This is an issue well beyond game consoles. Apple announced price hikes on its computers and tablets today as well. Game File is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Subscribe Item 2: Brutal Bungie cuts Bungie laid off “most” of its Destiny development team and some developers who worked on Marathon, the newest game from the struggling Sony-owned studio. A WARN notice issued by Sony to Washington State, where Bungie is based, tallied cuts impacting 292 workers, effective next month. That’s strictly for Bungie/Sony jobs in Washington and wouldn’t account for any elsewhere. The video I clipped below shows the redacted list of Bungie cuts filed to Washington State officials. As you’ll see, I had to scroll for a while… In a note emailed to PlayStation workers and published online, PlayStation game studios chief Hermen Hulst offered the following explanation for these latest cuts at Bungie: This is painful news, especially for talented colleagues whose roles have been eliminated. This decision was made only after extensive discussion and careful consideration, and I want to provide some context on how we arrived here. Over the past several months, together with Bungie leadership, we reviewed the studio’s long-term direction, development priorities, resource needs, and role within our broader portfolio strategy. We explored multiple alternatives before concluding that a reduction was necessary to align the studio’s resources with its current priorities and long-term goals. In 2022, Sony bought Bungie for $3.7 billion. The studio’s marquee game, the multiplayer live service shooter Destiny 2 was losing popularity at the time. Its next game Marathon, released earlier this year, has been well-reviewed but had a slow start. Bungie is renowned for making great shooter games, and Destiny fans have mourned the wind-down of Destiny 2. They’ve also expressed bewilderment over reports that Destiny 3 is not, per Bloomberg, immediately in the cards.
Lionel Richie postpones concert at United Center in Chicago following health scare at Minnesota show
Lionel Richie has postponed his concert this week at the United Center in Chicago following his health scare at during his first performance in a tour with Earth, Wind and Fire.
Lionel Richie postpones concerts after falling ill during tour opener
Lionel Richie is pausing his return to the stage after abruptly falling ill during the opening of his new tour.
Android 17’s new foldable gaming mode could make flippy phones more fun
A whole half of your screen will be dedicated to touch controls.
Making Our Own Luck
We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.
The Supreme Court lets Trump deport people back to war zones
Trump’s administration may ignore procedural rules governing many of the most endangered people in America.
GLP-1 and reduced cancer risk discovery earns UT Health San Antonio fellow prestigious Helio NextGen Disruptor Award
Colton Frisco Jones, MD, a 2nd-year fellow at the Mays Cancer Center at UT Health San Antonio, the academic health center of The University of Texas at San Antonio (UT San Antonio), recently earned the prestigious Healio NextGen Disruptor Award at the American Society of Clinical Oncology (ASCO) 2026 annual meeting in Chicago.
First-of-its-kind discovery earns UT Health San Antonio Mays Cancer Center fellow prestigious Helio NextGen Disruptor Award
Colton Frisco Jones, MD, a 2nd-year fellow at the Mays Cancer Center at UT Health San Antonio, the academic health center of The University of Texas at San Antonio (UT San Antonio), recently earned the prestigious Healio NextGen Disruptor Award at the American Society of Clinical Oncology (ASCO) 2026 annual meeting in Chicago.
Scientists Analyzed the Bones of ‘Skeleton Lake.’ What They Found Made No Sense.
Roopkund Lake sits in a frozen pocket of the Himalayas where hundreds of people died across a millennium. So why did researchers find bones from the island of Crete there?
Marvin Mims Jr. shares honest thoughts about future with Broncos
Denver Broncos wide receiver/return specialist Marvin Mims Jr. seems to understand his time with the team could be nearing an end.
My Music Row Story: Big Machine Records/Nashville Harbor Records & Entertainment’s Allison Jones
With over 35 years of experience in the music industry, Allison Jones serves as EVP of A&R at [...]
San José Postpones Plan to Double Downtown Parking Rates After Business Owner Uproar
Advocates for downtown businesses said the increase would hit the service industry hardest.
Leslie Jones says being typecast as 'angry' on 'SNL' was 'frustrating'
Former "Saturday Night Live" star Leslie Jones is looking back on the "frustrating" feeling of being typecast as a certain kind of "angry" character on the show.
What Are Colts' Best and Worst-Case Scenarios in 2026?
It's apparent that the Indianapolis Colts' success in 2026 lies heavily on quarterback Daniel Jones' shoulders.
Pat Kelsey & The Snub
Sunrise/ Sunset/ Since the beginning it hasn’t changed yet/ People fly high begin to lose sight/ You can’t see very clearly when you’re in flight — “On Your Way Down” Allen Toussaint To be honest I didn’t pay much attention initially when Pat Kelsey was first asked Monday morning about not being invited to attend […]
Google’s New $100 Speaker Makes a Weak Case for Gemini in the Home
The Google Home Speaker is the first new device of its kind to come from Alphabet Inc. in six years. In that time, Google has reshaped itself as an industry leader in artificial intelligence, with its Gemini platform now ubiquitous across consumer hardware like smartphones and web services like Search, Workspace and YouTube.
As Ebola cases surge above 1,000, experts say outbreak could be worst ever
Insufficient contact-tracing and the refusal of many residents to avoid contact with the bodies of loved ones killed by the Ebola virus are accelerating the epidemic.
Prime Day 2026: Top Savings on Anker, Beats, TVs, and More Accessories
Earlier this week we highlighted some of the best Apple-related product discounts that you can find on Amazon during Prime Day, and now we're focusing on third-party accessory markdowns during the event. In this article you'll find all the best accessories for charging, smart homes, smartphones, and more. Note: MacRumors is an affiliate partner with some of these vendors. When you click a link and make a purchase, we may receive a small payment, which helps us keep the site running.
Men’s Health: Caring for the Body, Mind and Spirit
FORT POLK, La. — Seeking help is often viewed as a vulnerability in military culture, but healthcare providers at Bayne-Jones Army Community Hospital are reframing it as a tactical strength. In observance of Men's Health Month, a BJACH family physician, a mental health provider and the hospital chaplain have partnered to deliver a unified message: peak military readiness requires actively maintaining the body, mind and spirit. From utilizing routine screenings to leveraging physical discipline to build mental resilience and cultivating a strong spiritual community, the team outlines actionable steps to overcome the physical, emotional and isolation barriers that uniquely impact men.
We asked MLB players: Where do you want to play? Where would you run from?
Which organizations have good reputations among players? Which ones have ... less good reputations? We went straight to the source to ask.
The new power broker: How Zohran Mamdani muscled NYC’s Democratic establishment
New York politics and the Democratic Party have a new power broker after Zohran Mamdani’s picks swept three US House primaries. Hakeem Jeffries, the Brooklyn-based House Democratic leader, is losing two incumbent members and facing an ascendant band of agitators. And the people long in charge in Democratic politics, including the ones who for decades thought of themselves as the insurgents, aren’t happy about it.
Lakers have reportedly called Pelicans about Yves Missi
The Lakers are actively hitting the phones in an attempt to upgrade at the center position.
Early humans were bringing fire into caves 1.8 million years ago
A new study suggests early humans were using fire in South Africa’s Wonderwerk Cave as far back as 1.79 million years ago. Researchers found burned bones deep inside the cave, where natural wildfires could not have reached, indicating that fire was likely carried in and maintained by human ancestors. The discovery pushes back the timeline for fire use and reveals surprisingly sophisticated behavior long before humans could create fire on demand.
A review argues the family dog may become science’s unlikely ally against autism
This peer-reviewed Perspective synthesizes a decade of research on a surprising candidate for autism science: the laboratory Beagle. Drawing together scattered studies, the review authors argue that dogs carrying engineered changes in the Shank3 gene reproduce core human features of autism spectrum disorder, including social withdrawal, altered sensory responses, and reduced attention to the eyes of a face. The synthesis assembles, for the first time in one place, the parallels between mutant dogs and autistic people, alongside early signals that oxytocin, a psychedelic, and a third compound may soften these traits. The authors frame the dog as a complementary, ethically governed model, not a replacement for existing ones.
Marvin Mims gets brutally honest over Denver Broncos offseason moves
When the Denver Broncos completed their NFL blockbuster trade for Miami Dolphins wide receiver Jaylen Waddle, they moved one step closer to Super Bowl contention. A player of Waddle’s caliber almost certainly raises the ceiling of head coach Sean Payton’s…
Google Pixel phones get better wireless audio quality in Android 17
While wired audio is certainly trying to make a comeback, wireless earbuds and headphones are more prevalent today than ever...
iOS 27 Wallet App Gets 7 New Features
Apple is making more of an effort to turn the iPhone into a physical wallet replacement in iOS 27, and there are several upgrades to the Wallet app. Pass Upgrades Apple upgraded airline boarding passes in the Wallet app with iOS 26, and in iOS 27, upgrades are coming to additional types of passes.
These are the 19 best Prime Day phone deals I'd actually buy myself
Prime Day 2026 has officially started. Save hundreds right now on smartphones, including the Google Pixel 10 Pro and Samsung Galaxy S26.
Ebola Symptoms in Current Outbreak May Be Milder Than in Previous Ones
That is good news for patients, but officials fear it will make controlling the spread of the disease harder.
Smart drones, safe skies: Student’s system tests, coordinates drone fleets
Doctoral student’s project devises an autonomous airspace coordination system built around a real-time simulation and validation technology.
Apple's Foldable iPhone Could Lose Almost $1,300 in Value in First Year, Study Suggests
A new resale value study suggests that a $2,000 foldable iPhone could lose as much as $1,292 of its value within its first 12 months on the market, based on current foldable depreciation trends. The estimate comes from SellCell, which analyzed the 12-month resale performance of flagship smartphones from Apple, Samsung, Google, Motorola, and OnePlus.
Dogs or cats: which is actually smarter, according to science - Futura-Sciences
It is one of the oldest arguments between pet owners, and it usually generates more heat than light. So what happens when you ask science instead of your group chat? The honest answer is that “smarter” is a slippery word, but researchers do have one hard number that tilts the...
This four-winged dinosaur may have terrorized Earth's earliest birds
A newly discovered feathered dinosaur called Jian changmaensis may be the missing predator responsible for mysterious piles of crushed prehistoric bird bones in China. The four-winged glider, a close cousin of Velociraptor, helps reveal how early birds and their dinosaur relatives shared the same ancient landscape.
What Owners Say Is The Biggest Problem With Foldable Phones
Some of the things people don't like about foldables are the durability of the hinge, the subpar battery life, and the strange aspect ratio.
Indonesian Academy of Sciences launches journal with Taylor & Francis
Publication will be "source of original research spanning science, technology, mathematics and the social sciences"
Outrage rescued an important ocean research program. Crucial ones remain at risk.
Senators saved a network of ocean sensors from "supreme stupidity." But other cutting-edge efforts are running out of funding, too.
Exclusive: Downed US pilot reported seeing Iranian drones swarm in ‘jellyfish’ formation
A US fighter jet pilot rescued by special forces after being shot down over Iran in April described a shocking sight before ejecting from his aircraft: multiple Iranian drones hovering in the air, moving as one, in a formation that resembled a jellyfish, according to four sources familiar with the matter.