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Scripps Oceanography and Ocean Science Trust Chart Path to Flood Resilience in California
A new OST and Scripps Institution of Oceanography report offers eight recommendations to improve catastrophe flood modeling and link mitigation efforts to insurance pricing, positioning California as a national leader in coastal flood resilience.
iPhone 17 Pro vs. iPhone 18 Pro: 35+ Upgrades Compared
Apple yesterday announced the iPhone 18 Pro and iPhone 18 Pro Max, succeeding the iPhone 17 Pro that launched last September. The new models are built around the A20 Pro chip, a 48-megapixel Fusion Main camera with variable aperture, a redesigned vapor chamber, and a smaller Dynamic Island. Last year's iPhone 17 Pro brought one of the biggest design changes to the lineup in years, switching from a titanium frame and glass back to an aluminum unibody with Ceramic Shield 2.
Apple Watch Series 12 and Apple Watch Ultra 4 Have Increased RAM Without Price Increase
MacRumors has confirmed that the Apple Watch Series 12 and Apple Watch Ultra 4 have increased RAM compared to the previous-generation models. Both new models are equipped with 4GB of RAM, according to Apple's developer tool Xcode 27. Apple Watch Series 11 and Apple Watch Ultra 3 models are equipped with 2GB of RAM, so the Series 12 and Ultra 4 have twice as much memory.
IBM, NASA launch AI model to help map ice, craters on Moon
IBM and NASA on Thursday released an open-source AI model designed to help scientists analyze decades of lunar observation data and support plans for a sustained human presence on the Moon.
Consulting firm Keystone opens new D.C. office — and already needs more space
Keystone opened its D.C. office in June and already needs at least 25% more space to accommodate its growing headcount, its CEO said.
Scientists want to 3D print houses on Mars with the help of yeast
Mars is a terrible place to build a house. It’s bitterly cold, blasted by radiation, and a near vacuum. Not to mention that the building materials, even for a modest shelter, could spend months hurtling through space before construction begins. But they don’t have to. In a study publishing September 10 in the journal Chem Circularity, researchers developed a recipe that could one day be used to 3D print houses on Mars. The recipe combines Martian rocks with Earthly ingredients: gelatin and yeast. Once dried and hardened, this living building material is as strong as low-grade concrete and can be broken down, recycled, and brewed again for new construction.
Moon's surface will be mapped in incredible detail using first-of-its-kind AI, NASA and IBM reveal
IBM and NASA have partnered to create the Lunar Foundation Model, a new AI capable of processing decades of lunar data so we can more accurately map the moon's surface.
NASA, IBM Launch AI Foundation Model for Lunar Science
NASA is bringing artificial intelligence to the study of the Moon, helping researchers transform how they analyze the Moon’s surface. In an ongoing
American Heart Association PREVENT equations now integrated into national electronic health record platform
DALLAS, Thurs., Sept. 10 — The American Heart Association Predicting Risk of cardiovascular disease EVENTs™ (PREVENT) equations are now integrated into Epic's electronic health record (EHR) platform, making modern cardiovascular risk assessment now...
iPhone 18 Pro and Pro Max Benchmarks Reveal Speed of A20 Pro Chip
Early benchmark results for the A20 Pro chip in the iPhone 18 Pro and iPhone 18 Pro Max appeared early this morning in the Geekbench 6 database, offering us a first look at the new models' CPU and graphics performance ahead of the devices reaching customers.
RTI Hits the Xcelerator
RTI International is expanding a facility that helps startups develop new technologies. The effort comes after federal funding cuts upended its business model.
India gets one of world's steepest iPhone price hikes
Apple raised prices on its existing iPhone lineup in India by as much as 41% within hours of unveiling newer models, bucking its usual practice of discounting older variants and marking one of the steepest hikes in any market where it has repriced this year.
DAILY THREAD
The Daily Merengue is a place where you can feel free to discuss all things football. Do not be alarmed by the overt RMCF bias. It’s in the name! Shoutout to the mods who do a fantastic job Kung_Fu_Zizou, Juninho, NeRObutBlanco, Felipejack, Ezek Ix and yours truly, Valyrian Steel. Well better get used to it. […]
Nintendo’s latest Switch 2 update adds VRR support in TV mode
The new firmware update also includes nostalgic Mii themes
Modders Unlock DLSS Multi Frame Generation For RTX 30-Series "Ampere" GPUs
After porting DLSS 5 to every recent NVIDIA generation, the modding community now seems to be turning its focus to Frame Generation. A new mod called DLSSG SM86 lets GeForce RTX 30-series owners run DLSS Multi Frame Generation in 2X and 4X modes, a feature NVIDIA officially reserves for RTX...
Ralph Lauren delivers modern take on romance with sensual silhouettes
Ralph Lauren's New York Fashion Week show featured a starry guestlist with actors from Meghann Fahy, Cynthia Erivo, Viola Davis and Elizabeth Debicki in attendance. The designer's Spring 2027 show
Viewpoint: Unlocking Europe’s wildfire data
Europe is already investing in the science, technology and infrastructure needed to understand, prevent and fight wildfires. Copernicus provides satellite-based Earth observation and environmental information, while the European Forest Fire Information System provides information on fire danger and forest fires across Europe. Weather and climate systems add forecasts of heat, drought, wind and humidity; historical fire databases show where fires have occurred; and researchers generate increasingly detailed knowledge about fuels, fire behaviour, forecasting, modelling and risk management. Meanwhile, new European research projects are adding digital twins and other tools to this growing ecosystem.However, these data do not necessarily sit together, nor are they necessarily described, structured or governed in ways that allow them to be used together. Much of the information is public, but some is commercially held. Some is sensitive. Some is subject to legal, security or operational restrictions. Even when data can be legally accessed, different systems may use different formats, terminology and rules.Europe therefore faces an unusual paradox: we have vast amounts of relevant information to respond to the wildfire challenge, but not the means to bring it together. For example, a wildfire researcher or emergency service might need to ask whether a particular combination of vegetation, drought, wind and topography has historically been associated with rapid fire spread. The relevant information may exist in several institutions, using different systems and subject to different conditions of access.The challenge is to conduct an authorised analysis that interacts with these sources, combines the results and respects the rules imposed by each data custodian.An important part of the answer can be found in the Fair principles, the idea that data should be findable, accessible, interoperable and reusable. Developed more than a decade ago, these principles have become a central reference point for modern data stewardship, making it easier for people and machines to find data, understand what it means and determine whether it can be reused.Readability by machines is essential, since AI systems will be key to meeting the data challenge. Bring analysis to the dataThe proposition is not to give an AI system unrestricted access to sensitive databases. Quite the opposite. The goal is to make it possible for approved algorithms to go to the data, rather than requiring sensitive data or large datasets to be copied to wherever the analysis happens.Imagine an analysis asking a series of questions of different data stations. At one station it might examine weather and climate data; at another, historical fire records; at another, experimental measurements of fire behaviour. The algorithm does not need to download everything. It can operate within the environment permitted by each data custodian and return only the results that the rules allow to leave.This is sometimes described as data visiting, and related approaches already exist in areas such as federated analysis and federated learning.Sensitive data should therefore not be treated as a free-for-all for machines. This requires appropriate governance at multiple levels. Access needs to be authenticated and authorised. The purpose of an analysis should be defined. The code or model being run should be controlled. Data custodians should be able to specify what can be queried and what results can leave their environment. Activities should be auditable and human oversight should remain where the consequences require it.In other words, the objective is not to trust AI with the data. It is to design systems in which AI never has more access than it needs.As open as possible, as closed as necessaryFair data should also not be confused with open data. Some wildfire data should be openly available. Other information may legitimately need to remain restricted because it concerns critical infrastructure, security, commercial interests, privacy or operational capabilities. The principle should be: as open as possible, as closed as necessary.The important point is that restricted data should not automatically become unusable data. If machines can discover what information exists, understand its meaning, establish where it came from and determine the conditions under which it can be used, authorised analyses can potentially be carried out without the underlying data ever leaving the environment in which it is protected.Restricted data can still be Fair and machine-actionable.This is also an important question of data sovereignty. European institutions should not have to surrender control of their data to a handful of technology platforms in order to benefit from AI. Nor does Europe need to start again by building one giant repository for every piece of wildfire information. The better approach is to connect what already exists.This is the principle behind emerging approaches such as Tryangle, developed through the Leiden Initiative for Fair and Equitable Science. Rather than creating another centralised data warehouse, the approach seeks to provide an interoperable layer through which approved algorithms can visit distributed data sources while respecting the rules of their custodians.In this way, a data station can remain where it is. Its custodians can retain control. Existing databases and applications do not have to be abandoned. What changes is their ability to communicate with other systems through common, machine-readable descriptions, access rules and interoperability mechanisms.But approaches like this need data that meets the Fair principles. Only then can an interoperable ecosystem safely begin to turn fragmented information into collective intelligence.Data infrastructure is wildfire infrastructureThe implications of this approach are entirely practical. Firefighters could gain better intelligence about local and evolving risks. Land managers could test prevention strategies using more comprehensive information about fuels, weather and past fires. Researchers could compare evidence across ecosystems without repeatedly moving huge datasets between institutions. Smaller regions and resource-constrained teams could access analytical capabilities without having to build large data infrastructures themselves.Europe is already investing heavily in satellites, databases, research programmes, forecasting systems and scientific expertise. The question is whether we will connect those investments well enough to turn them into actionable intelligence.That requires policymakers and funders to treat data infrastructure as seriously as physical infrastructure. Data generated or supported through European public funding should be Fair, verifiable and machine actionable by design, wherever legally and ethically possible.Related articlesData Corner: Europe’s burning need for wildfire mitigation researchClimate monitoring must remain a global enterprise, experts sayIn practice, that means funding not only the production of data, but also the infrastructure that makes data usable across systems: metadata, provenance, interoperability, access mechanisms and governance. Where data must remain restricted, we should ensure that it can still be securely discovered, verified and used for authorised analysis.Initiatives such as the European Open Science Cloud offer an existing framework through which these principles can be put into practice. What is needed now is to accelerate implementation and make them a standard part of how Europe funds and builds research and innovation systems.We do not need another generation of disconnected databases. The data is already there. The opportunity is to make it work together, securely, responsibly and quickly enough to help prevent the next fire, rather than simply document the last one.Jean-Claude Burgelman is professor emeritus at the Free University of Brussels (VUB) and editor-in-chief at Frontiers Policy Lab. For more than 20 years he held leading roles in research and innovation policy at the European Commission.
New wave of healthcare fraud enforcement
In past years, federal and state authorities typically initiated healthcare fraud investigations based on whistleblower complaints and audits. While that still occurs, the model is changing. Federal enforcement agencies are increasingly using sophisticated data analytics, artificial intelligence, and coordinated investigative efforts to identify potential fraud. The Department of Justice (DOJ),…
iPhone 18 Pro is eSIM-Only in These Countries
Apple has been phasing out the SIM card tray on iPhones, with the latest models relying solely on eSIM technology in select countries. According to Apple, the iPhone 18 Pro and iPhone 18 Pro Max support eSIMs only in these countries and regions: Bahrain Canada Guam Japan Kuwait Mexico Oman Qatar Saudi Arabia United Arab Emirates United States U.S. Virgin Islands iPhone 17 Pro models are eSIM-only in the same countries, so there is no change this year.
Anthropic researcher's resignation sends warning about the dangers of AI development
Jacob Coxon, who said he spent three years doing research at both Anthropic and OpenAI, said Tuesday on the social platform X that the two AI companies are more focused on beating each other and global competitors in developing the most advanced model possible than they are on safety.
Hollywood’s ‘new business model’ comes into view as Gen Z shows a moviegoing taste that combines ‘fast food and fine dining’
Theaters sold nearly 249 million fewer tickets than in 2019 but still set a $4.7 billion summer record. It’s not 2019 anymore.
Apple Reveals iPhone 18 Pro and iPhone 18 Pro Max Battery Capacities
Apple has confirmed the battery capacities for the iPhone 18 Pro and iPhone 18 Pro Max models that the company announced earlier today. Apple is required to publish energy labels on its iPhone product pages in the EU, and they reveal the official mAh battery capacities for the devices. Here are the battery capacities for the iPhone 18 Pro and iPhone 18 Pro Max models that still have a SIM card tray, according to Apple: iPhone 18 Pro: 4,056 mAh (+1.7% vs.
If Meta Glasses Freak You Out, Wait Until You Hear About the New Apple Watch Features
Live Rewind and Siri Recap just killed the dreams of always on AI wearables.
There are new shiny iPhones, so Apple is making you pay more for older models
Apple is raising the price of its existing iPhone models by $100, including iPhone 16, iPhone 17, and iPhone Air.
Apple's Fine Print: Daily Usage Limits for Siri AI, 'Expanded Access' Coming for a Fee
Apple today confirmed that there will be a daily usage limit for Siri AI, with expanded access available for a fee in the future. In the fine print of Apple's announcement of the Health Sensing features coming to the Apple Watch Series 12 and Apple Watch Ultra 4, Apple says it will have usage limits on Siri AI, intelligent photo editing tools, Image Playground, and Apple Foundation Cloud models in the Shortcuts app.
Pixel 11 Pro vs. iPhone 18 Pro: Which to Buy?
Apple shared its new hardware line-up for the end of 2026 today, revealing the iPhone 18 Pro, iPhone 18 Pro Max, iPhone Duo, new Apple Watch models, and some new AirPods. For those who missed the event and don’t want to re-watch, yet still want to see how the new iPhone 18 Pro compares to...
iPhone 18 Pro Models and iPhone Duo Feature Apple's New C2 Modem
Apple today unveiled new iPhone 18 Pro models and the iPhone Duo – the company's first foldable iPhone – and all three devices feature Apple's new custom-designed C2 modem for 5G connectivity. Prior to today's announcements, there was speculation that Apple's C2 in-house modem would not support mmWave 5G in the U.S., and that the company would once again rely on Qualcomm to fill the gap for American carriers. Apparently, that's not the case.
China slams US claims of ‘industrial-scale’ AI theft
The response comes after three US agencies accused Chinese AI companies of exploiting American AI models.
Apple debuts $129 AirPods 5 with better noise cancellation and transparency mode
AirPods 5 with noise cancellation is cheaper than its predecessor.
Apple Discontinues iPhone 17 Pro and iPhone 17 Pro Max
Following the announcement of the iPhone 18 Pro models today, Apple discontinued the iPhone 17 Pro and iPhone 17 Pro Max. Apple usually retires its Pro models with the release of their successors, and this year that's no different. Both the iPhone 17 Pro and iPhone 17 Pro Max are no longer available on Apple's online store. The iPhone 17 Pro and iPhone 17 Pro Max were introduced in September 2025, at Apple's "Awe dropping" event and released later the same month.
Here’s how the new iPhone 18 Pro stacks up to the last-gen models
It’s time for a good, old-fashioned spec showdown.
Apple Raises Prices of iPhone 16, iPhone 17, iPhone Air, and iPhone 17e
Behind today's iPhone 18 Pro and iPhone Duo announcements, Apple has raised the prices of the existing iPhone 16, iPhone 17, iPhone Air, and iPhone 17e on its online store. The new starting prices for the three models now look like this: iPhone 16: $799 (+$100) iPhone 17e: $699 (+$100) iPhone 17: $899 (+$100) iPhone Air: $1099 (+$100)So that's a $100 price hike on all four existing models in Apple's iPhone lineup.
University of Iowa Health Care nixes plans for new $2B tower
University of Iowa Health Care has scrapped plans to build a new $2 billion inpatient tower — at least for now — and rather is “modernizing and expanding existing spaces across the health system, specifically on the university and downtown campuses.”
Apple is raising iPhone prices by $100 on all of its old models
The price increase impacts the iPhone 16, the full iPhone 17 lineup, as well as the iPhone Air.
iPhone Duo Supports MagSafe Charging
Rumors about the foldable iPhone were unclear on whether it would have MagSafe charging, but it turns out the iPhone Duo does indeed have a magnetic charging array. Tech specs for the device say it supports MagSafe wireless charging at up to 25W, the same as the iPhone 18 Pro models. It also supports Qi2.2 25W wireless charging when using third-party accessories. Faster wired charging is available, with the iPhone Duo charging to 50 percent in a 20-minute period.
Apple skips the base iPhone 18 at its fall launch event
Apple is focusing on higher-priced iPhone models this fall.
The Apple Watch Ultra 4 Is an Even Better Heart Health Companion
Apple's high-end smartwatch also comes with the new internals of the Apple Watch Series 12 and even longer battery life.
The Apple Watch Series 12 Will Track More Than Just Health Data
Even with a return of ceramic frames, the most important new features for Series 12 are all built around health and conversation tracking.
New Apple Watch Series 12 highlights: improved health sensing system, Readiness app
In an update with few visible changes to the Apple Watch Series 12, in conjunction with watchOS 27, the new model has a new health app called Readiness, and a series of new health monitoring features.
Apple Announces iOS 27 Release Date
At its event today unveiling the iPhone 18 Pro, AirPods 5, Apple Watch Series 12, and more, Apple announced that iOS 27 will be released later this month. iOS 27 has already been available as a developer beta since June and as a public beta since July, and Apple today said that the update will be released for all users with a compatible iPhone model on Monday, September 14.
Apple Watch Series 12 announced: Features, price, release date
Apple Watch Series 12 and Apple Watch Ultra 4 are official. Apple has announced its two new Apple Watch models...
Apple Announces Apple Watch Series 12 With S11 Chip, Upgraded Health Sensors and Ceramic Models
Apple today announced the Apple Watch Ultra 4, featuring a new S11 chip, a redesigned health sensing system, and a larger battery that Apple says delivers two days of battery life. With improved power efficiency, Ultra 4 offers up to 18 hours of workout tracking with full GPS and heart rate monitoring, or 45 hours in its maximum extended workout mode. It comes in Black and Natural titanium, alongside new band colors and a new titanium Hermès band.
Apple raises iPhone prices for new Pro models
Apple unveiled the iPhone 18 Pro and Pro Max at its launch event. Prices start at $100 more than the previous models.
AirPods 5 Announced With Improved Noise Cancellation, Audio Quality, and More
Apple today introduced AirPods 5, bringing Active Noise Cancellation to its entry-level wireless earbuds at a starting price of $129. Apple says AirPods 5 remove up to 50% more external noise than AirPods 4 with Active Noise Cancellation. A redesigned acoustic architecture and updated Adaptive EQ also promise richer, more detailed sound, while an improved Transparency mode makes nearby voices and sounds more natural.
Spiraea genome reveals how Rosaceae evolved a key defense hormone
A chromosome-level genome of Chinese spiraea reveals how the rose family conserved and remodeled a major route for producing salicylic acid, a hormone central to plant immunity and environmental stress responses.
iPhone 18 Pro and 18 Pro Max Both Have Crazy Battery Life
No regular iPhone 18 this year. Just two Pro models.
Apple Reveals iPhone 18 Pro Models Will Be Available in Four New Colors
Apple at its annual fall iPhone event has revealed that the new iPhone 18 Pro and iPhone 18 Pro Max models will be available in four new colors. Apple describes the new colors as a Deep Black, a refined Silver, a new Glacier Blue, and Burgundy – calling the latter a "sophisticated and unique new color" that's obviously meant to be a successor to the iPhone 17 Pro's Cosmic Orange.
NovaOne Launches Next-Generation Platform Uniting Behavioral and Physical Health
NovaOne today announced general availability of its next-generation solution: a modular platform, uniting purpose-built preventive tools, clinically validated assessments, an AI care navigator with deep human clinical oversight and a curated network of evidence-based specialty providers. One platform for integrated preventive and curative healthcare.
UN hails Libya election deal as Security Council urges Libyans to seize the moment
The UN Security Council has welcomed a breakthrough agreement between Libya's rival political blocs, calling it "an important step" towards the country's first national elections in over a decade – while pressing all sides to move quickly from paper to practice.
Museum of Discovery and Science, Broward libraries bring hands-on learning to communities
The Museum of Discovery and Science and Broward County Library are bringing hands-on learning and character development to communities across Broward County through Character Corners, an initiative inspired by MODS’ Build a Better World: The Future Begins with You exhibit.
Climate NGOs clash over the role of science in UN negotiations
Disagreements within Climate Action Network International have intensified over the IPCC's role in UN climate negotiations and the fairness of its models.
Lava-Covered Planets Are Defying a Key Rule of Planetary Science
Researchers developed a model showing how lava-covered planets close to their stars can hold onto their atmospheres, which could help guide the search for life beyond our solar system. Some planets orbit so close to their stars that intense radiation should strip away their atmospheres. Yet several of these scorching, lava-covered worlds still retain thick
NASCO and Doxim Partner to Modernize Health Plan Administration and Improve Communications
/PRNewswire/ -- NASCO, a leading provider of healthcare technology solutions, today announced a strategic partnership with Doxim®, a leader in customer...
NASCO and Doxim Partner to Modernize Health Plan Administration and Improve Communications
NASCO, a leading provider of healthcare technology solutions, today announced a strategic partnership with Doxim®, a leader in customer communications management (CCM) and engagement technology for highly regulated markets. The collaboration brings together NASCO's deep health plan administration expertise with Doxim's omnichannel communications capabilities to help health plans modernize operations and deliver more seamless, personalized experiences for all healthcare stakeholders.
The Elder Scrolls V: Skyrim Official IKEA Mod Features Matt Berry as a Kallax Storage Companion
What We Do in the Shadows' Matt Berry voices an IKEA Kallax bookcase in a free official Creation for The Elder Scrolls V: Skyrim.
VA Health Records Overhaul Stalls Despite Restart Push
VA's electronic health records modernization hits another roadblock. Learn why the fourth attempt faces delays and what it means for veterans' care.
Gracenote Expands AI Product Roadmap with Sports MCP Server, Entertainment SLM and Agents
/PRNewswire/ -- Gracenote, Nielsen's content intelligence business, today unveiled the next phase of its AI product roadmap. Anchored by its Video Model...
Leaked Video Shows iPhone 18 Pro's 3-in-1 Dynamic Island in Action
A leaker has activated Apple's upcoming three-item Dynamic Island mode inside the iOS 27 simulator, offering the first video demonstration of the new iPhone 18 Pro feature. The leaker, known as pdfu, posted a video showing the Dynamic Island toggling between three simultaneous Live Activities, matching what Bloomberg's Mark Gurman described in his report earlier today. "The new Dynamic Island with 3 items is already supported in iOS 27," pdfu wrote.
Scientists Say They Can Now Pinpoint Where Big Quakes Might Hit
A GPS-based algorithm is used to identify where stress has been building up.
The Catalytic Opportunity Fund: A financing model to accelerate introduction of new and underused SRH products
New evidence from the Catalytic Opportunity Fund on pooled, rapid financing for reproductive health product introduction in low- and middle-income countries.
Dutch scientists pipe office urine into bacteria-filled cells that generate electricity and recover nitrogen and phosphorus, while a related system can produce hydrogen
Pee breaks are one of the most relaxing times in the office when you finally get to have some sane moments to yourself. Which is why most employees take numerous such breaks within a day.
India's Serious Fraud Office recommends 'detailed' probe into Xiaomi's business in country
India's Serious Fraud Office has recommended Xiaomi be investigated for alleged irregularities in its business model and compliance with foreign investment law, potentially intensifying scrutiny of the smartphone maker, a government document shows.
NEA partner Aaron Jacobson weighs in on open versus closed
Big Tech may be grabbing attention for its powerful new models, but investors like NEA's Aaron Jacobson want companies to explore their options.
Germany must relearn the language of power-politics
To protect Europe from Russian aggression, Germans must resolve a tension that lies the heart of their modern national identity: a clash between the ideals of ‘Never Again Fascism’ and ‘Never Again Germany’.
How A.I. Tokens Work
As large language models become more advanced, they use ever more resources. Who will foot the bill?
Nonprofits Are Helping Musicians Pay for Insurance in Austin, Texas, and Beyond
A nonprofit and a local public health agency are subsidizing marketplace health insurance for Austin music artists, even as shifting marketplace conditions make the program a more expensive proposition. It’s becoming a model for other cities and sectors.
Scientists and algorithms: Finding the right balance in modern drug development
The future of drug development is not scientists versus algorithms. It is scientists and algorithms working together.
Can Innovative Fabric Science Solve the Workplace Safety Crisis? "All Access hosted by Andy Garcia" Explores Breakthroughs with Portwest
/PRNewswire/ -- Filmed on August 25, 2026, a new segment of "All Access hosted by Andy Garcia" highlights how modern material science is tackling...
From moving people to managing them
Transportation policy used to have a fairly uncomplicated purpose: move people safely, efficiently and reliably. Build roads where people drive. Maintain bridges before they fail. Add capacity where growth overwhelms the system. Provide transit where it makes sense. Infrastructure was supposed to accommodate human behavior. Colorado increasingly prefers the opposite arrangement. Today, transportation policy is […]
Cleveland Clinic, RIKEN and IBM Team Advance to Finals for 2026 ACM Gordon Bell Prize
Joint research team modeled a 12,635-atom protein, the largest-known to be simulated using quantum computers. Breakthrough was achieved through quantum and classical methods working together, expanding quantum-centric supercomputing’s potential in life sciences research.
Mack Cleveland: Using computational materials science to engineer higher burnup fuels
Propelled by a love of mathematics and materials science, the MIT doctoral student models granular chemical reactions in uranium dioxide, work that might lead to less fissile nuclear waste and improved plant performance.
SBA promotes CHOICE Arrangements for small-business health benefits
The SBA and CMS are promoting CHOICE Arrangements, formerly known as ICHRAs, as an alternative health benefits model for small businesses.
SBA promotes CHOICE Arrangements for small-business health benefits
The SBA and CMS are promoting CHOICE Arrangements, formerly known as ICHRAs, as an alternative health benefits model for small businesses.
West Virginia State Police cadets to begin mental health crisis training September 9
West Virginia State Police cadets will begin Keystone Model crisis training Sept. 9. Classroom lessons and realistic simulations will teach them to recognize behavioral health emergencies, communicate effectively and safely de-escalate encounters.
Pappas, Sununu sweep to victory in U.S. Senate primaries
Pappas, a moderate Democrat and current Congressman in the 1st Congressional District, will face off against Republican and former U.S. Senator John E. Sununu.
Chris Pappas Defeats Progressive Challenger in New Hampshire Senate Primary
Mr. Pappas, a moderate Democrat who has served four terms in the House, will face former Senator John E. Sununu, the Republican nominee, in November.
Cleveland Clinic, RIKEN and IBM Team Advance to Finals for 2026 ACM Gordon Bell Prize
Cleveland Clinic, RIKEN and IBM has been named as a finalist for the 2026 ACM Gordon Bell Prize for simulating the largest biologically meaningful molecules ever modeled with quantum computers, reaching a scale of 12,635 atoms.
The Nonlinear Science Behind Large Language Models
LLMs are black boxes, but the principles that govern them are not. Read this article for a detailed introduction to chaos and complexity theory applied to LLMs.
Hailey Bieber poses nude, opens up about her Brazilian roots
Hailey Bieber is saying more and wearing less. The 29-year-old model posed nude on the cover of photographer Renell Medrano’s ICE magazine, appearing in "Vol.
GOG brings back "big box" PC games, one printable template at a time
Preservation "goodies" also includes downloadable 3D models for desktop perusal.
Mapping the Global Health Landscape: Analysis of Fourteen International Organizations
The global health architecture includes a number of diverse international organizations with different mandates, governance models, financing structures, and operational approaches. This KFF resource looks across a range of variables to provide a descriptive mapping of 14 key global health and related international institutions. It is intended to inform discussions about synergies and coordination, duplication, comparative advantage, shared challenges, and architectural reform.
Exclusive: Two of gaming’s biggest names are making a big investment in gaming’s future
The first thing to know about the Nova Games Foundation is that it isn’t about The Game Awards. And it’s not about PlayStation. The ambitious new grant program is the brainchild of Geoff Keighley and Mark Cerny. Keighley is the host of The Game Awards, Summer Game Fest and Opening Night Live. Cerny is a game designer of some 45 years and the lead architect for the PlayStation 4 and 5. But this new thing, which they’re revealing through Game File, isn’t about their day jobs. It’s an unaffiliated, standalone philanthropic project. It’s a bet on the artistic future of video games and a way, they tell me, to give back. “I’m nearing the end of my career,” Cerny recently told me over email. “I’m not done yet, but paying it forward—in the best way possible—is very much on my mind these days,” The Nova Games Foundation is a university-affiliated fellowship program, intended to offer six-figure grants to 20 young game designers each year, potentially for decades to come. It will offer no-strings-attached funding along with mentorship from games industry leaders, a combination intended to aid the development of groundbreaking new games, Cerny and Keighley told me. Nova will begin accepting applications in December, from class of 2026 and 2027 students from 13 affiliated gaming programs at universities in eight countries. The schools working with Nova include the New York University and the University of Southern California in the U.S., along with Abertay University in Scotland, Cnam-Enjmin in France, TH Köln in Germany, and the Royal Melbourne Institute of Technology in Australia, Cerny and Keighley said. The plan: $100,000 per recipient, with about a quarter of Nova fellows eligible for up to $500,000 more for projects that are shaping up particularly well. Payments will be delivered based on development milestones, and recipients will own their games. Nova will help promote the work, and developers will be free to pursue the publishers and platforms of their choice. Nova can help introduce fellows to publishers, but won’t take a cut. “I’ve always wanted to give back, but given my role in the industry, I’ve never felt it appropriate to commercially invest in games,” Keighley told Game File. “I’ve never owned stock in a game company or taken a financial stake in a game. Nova is philanthropy: we aren’t taking equity or looking to recoup the grants. The return we’re hoping for is creative—helping new voices make games and find their footing. “Mark and I have each made multi-million-dollar donations to establish the foundation, and we intend to keep contributing. We hope others will join us.” Cerny and Keighley have already hired an executive director, John Maconga, and a head of grants, recent Game Developers Conference director Ashley Corrigan, to help launch the effort. They’re working to recruit game industry leaders to join the effort. Keighley says “dozens of leading game directors have already expressed interest in contributing their time.” To name one, they’ve already gotten Josef Fares, lead designer from It Takes Two and Spit Fiction studio Hazelight on board with a donation and pledge to help out. “I’m proud to support Nova because it gives the next generation of creators the freedom to explore their creativity and hopefully bring their unique visions to life,” Fares told Game File. A plan forged from a friendship Keighley and Cerny have known each other a long time. It’s been so long, Cerny isn’t even sure exactly when they met. “We travel in much the same circles and I’m sure first intersected in the 90s or early 2000s,“ Cerny said. Keighley thinks it might have been during his stint writing a column about the mid-’90s console 3DO for a gaming magazine while Cerny was working on games with Crystal Dynamics or on Way of the Warrior with Naughty Dog. They became genuine friends about a 10 years ago, Keighley said, as they bonded over a shared love of games and a hope to improve the industry. “About a decade ago, we started having dinner a few times a year in LA,” Keighley said. “Just to catch up on life and the industry. Those conversations continued over Zoom during COVID. Nova grew out of that friendship and a question we kept coming back to: ‘What could we do to help the next generation of game directors get started?’” Keighley credits Cerny with the idea to figure out a way to put their money and time back into the industry. At one of those dinners, Keighley proposed the idea of a fellowship program. He’d recalled applying for a Rhodes Scholarship when he was younger. “Spoiler: I didn’t get it,” he said. He’d admired the MacArthur Foundation’s so-called “genius grants.” He liked these kinds of programs that recognized people’s talents and gave them the financial boost and the freedom to realize their potential. With Cerny, he had pondered what a game industry version of that could be. Keighley liked the idea of centering the fellowship on students, drawing inspiration from the accomplishments of Jenova Chen, the USC game design graduate who went on to lead the creation of gently moving, ambitious games such as Flower and Journey. Keighley also thought it could be useful to help promising graduates bridge the transition from student to professional. “Joining an established studio isn’t always possible—especially in today’s market—and even then, it isn’t the right path for everyone,” Keighley said. A fellowship, he realized, could give “graduates the time, resources and guidance to pursue a game of their own and not worry about the commercial viability.” As the idea took shape, Cerny also saw an opportunity to enable more games of a certain type: “The target with the grants is games as an artistic medium,” Cerny told me. “We like to say games with ‘artistic, literary and societal value.’” He added: “I’m a pretty big gamer myself, though I tend to gravitate towards the smaller and more unique or artistic titles, games like Neva, Abzu, Gorogoa, Stray or Outer Wilds. I was just playing and Roger on a flight to Japan, and was getting misty eyed to a degree that I was concerned that a flight attendant would ask me if I was OK. “So one fun benefit here is the games that will come out of the Nova Games Foundation – I can’t wait to play them myself.” Cerny believes it will also be useful for Nova fellows to hone their craft and team leadership skills. “We are looking for the next generation of visionaries,” he said. “The trick is that they will also need to have the executive function necessary to drive a small project to completion.” Game File is a reader-supported publication. To receive new posts and support my reporting, please consider becoming a free or paid subscriber. Subscribe Going big with this Keighley and Cerny may have started Nova and may be the ones primarily backing it right now, but they’re dreaming of something that goes beyond them. “Mark and I may have helped get it started, but one of our measures of success is that Nova grows into something the entire games industry feels a sense of ownership in,” Keighley said. “Our ambition is to build a lasting endowment supported by people and companies across the industry, and an equally broad community of creators willing to give their time and experience to the next generation.” The industry has a lot of knowledge that it can pass to the next generation, Keighley said: “Nova can hopefully become a way to connect that generosity with talented young creators at the moment when it can make the biggest difference.” Cerny, who told me he believes Nova can mature “over the next 10 or 20 years,” sees an opportunity to give generations of game makers momentum. “The industry has changed immeasurably since I started in games in 1982,” he said. “These graduates have talent, training and tools that outclass what we had back in the day by an astonishing amount. But they face a tough road ahead getting traction in the industry, and many could benefit from our support. We want to be there to give it to them.” “There’s a personal side to this, too,” Keighley said. “I don’t have children, and I’ve spent a lot of time thinking about what I can do for future generations. Games have been my entire career. I’ve been incredibly fortunate, and helping someone else build a life in this industry feels like a meaningful way to give back.” Cerny’s oeuvre dates back to Marble Madness and Sonic the Hedgehog 2. He has stood on stage multiple times to reveal the future of PlayStation hardware. He’s been an executive producer for a string of modern PlayStation classics such as The Last Guardian and Marvel’s Spider-Man. Nevertheless, of Nova, he said, “It’s certainly not like anything I’ve done before.” Nova Foundation applications will be due in December and the first wave of fellows will be announced in March 2027. A full list of participating universities and steps students and recent graduates can take to apply to become a Nova Fellow is forthcoming.
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AZ's R&D chief Barr touts internal 'science success story' after IL-33 antibody's stellar showing in COPD
With a detailed data drop that AstraZeneca’s R&D chief described as an internal “science success story,” the British Big Pharma has secured an FDA priority review for what it believes could become a flagship biologic in chronic obstructive pulmonary disease (COPD). In detailed results from the late-stage Oberon and Titania trials—first teased in March and detailed in full at the European Respiratory Society Congress in Barcelona this week—the drugmaker laid out the extent of its IL-33 inhibitor’s potential to reduce moderate and severe exacerbations in a wide range of COPD patients still struggling with those “lung attacks,” as AstraZeneca’s Sharon Barr, Ph.D., called them, despite using standard-care inhaled therapy. In the headline results, a 300 mg dose of tozorakimab given once every four weeks curbed those moderate and severe exacerbations in the studies’ primary population of former smokers by 29% in the Oberon study and 34% in Titania. In the overall population of both current and former smokers, these reductions were 30% and 29%, respectively, versus placebo and inhaled standard of care. The benefits also extended to clinically meaningful exacerbation reductions in all prespecified patient subgroups and specifically turned up promising signals in patients across a range of blood eosinophil counts, with Barr telling Fierce that “it’s the details that make this even more exciting than the high-level results that we’ve already shared.” In fact, during AZ’s tozorakimab poster presentation at the ERS 2026 Congress this past weekend, attendees were so enamored by the data that event organizers had to encourage people to clear the room and look at the other presentations on offer, Barr said in an interview. “I think it really speaks to the fact that there is a lot of buzz around these data because the entire respiratory community has been so desperate for new therapies for these patients,” she explained. The respiratory disease continues to represent a “staggering unmet medical need,” Barr said, highlighting the COPD exacerbations that the Oberon and Titania studies homed in on, which she added carry a greater mortality risk than a heart attack. “When a patient has a severe exacerbation, only about half of them are still alive within three and a half years,” she pointed out. As for tozorakimab specifically, Barr christened the molecule “an AstraZeneca science success story,” harkening several years back to the point at which researchers began to explore IL-33 as a driver of respiratory disease, and COPD in particular. At the same time, “there was still so much that wasn’t understood,” she admitted, highlighting the insight that IL-33 signals through both ST2 and EGFR through the RAGE pathway, a discovery Barr attributed to AstraZeneca's own scientists. Understanding the need to tackle both pathways in COPD—and aware of competitor candidates in the hopper, including one that bound ST2—the company ultimately had to make some “courageous decisions,” Barr said. These included taking a prior COPD molecule offline and going back to the drawing board to reinvent its potential IL-33 label “to make sure that we had a molecule that could block signaling through both arms of the pathway, through both the reduced form and the oxidized form, knowing that we wouldn’t be first, but striving to be best.” “When we put [tozorakimab] into the clinic, we firmly believed that we had a differentiated molecule, and we saw the other molecules blocking just ST2 or partially blocking IL-33, unable to deliver two positive pivotal studies in COPD,” Barr explained. “We kept marching forward because we believed our molecule was differentiated, and now I think we have the clinical validation that supports that.” Ultimately, AstraZeneca finds itself on much better footing these days when it comes to potential biologic rivals to tozorakimab in COPD. Sanofi and Regeneron’s Dupixent, for instance, is approved to treat COPD exacerbations in patients with high eosinophil counts, but not low ones. Meanwhile, the future has become cloudier for other next-gen IL-33 candidates from Sanofi and Regeneron, as well as Roche, which have suffered trial flops in recent years. One other potential ingredient for AstraZeneca’s success in its duo of studies was that the company was “ambitious in the trial design, willing to look at an all-comers population,” Barr said, “and willing to enroll the most severe patients.” Prior studies for would-be biologics rivals in COPD “avoided enrolling” those patients, she pointed out. She also highlighted the Big Pharma’s painstaking design of exacerbations in its trial, which “gave us a very rigorous readout,” and pointed to “the extra effort and investment” the company put in to understand the effect of mucus plugs in patients. Barr described mucus production as a “key feature in disease diversity,” noting that mucus plugs—obstructing clumps of mucus that block patients’ airways—are associated with worse outcomes in COPD. In its data announcement, AstraZeneca noted that an integrated analysis of Oberon and Titania found tozorakimab “demonstrated a reduction in patients’ mucus plug score,” with the pharma claiming its biologic is the first to deliver such results in a broad COPD population. “So being able to reduce those mucus plugs, we expect, is an important part of driving benefit for patients who are living with COPD,” Barr said. Again touching on the breadth of the study populations, Barr added that tozorakimab “worked across all eosinophil levels in both current and former smokers across all levels of lung function,” which she suggested “really simplifies decision-making for clinicians, and it allows them to offer therapy to the broadest possible patient population.” In the highest patient eosinophil count group, tozorakimab helped chart a 43% reduction in exacerbation risk, which Barr stressed were “unprecedented data.” In the mid-level group, AZ’s drug delivered a 23% reduction and, in the lowest group, a 34% reduction in eosinophils, which Barr said suggests efficacy “in all patient subgroups.” As for AZ’s recent guidance upgrade on the medicine’s sales opportunity, the lift from a $3 billion to $5 billion range to $5 billion plus was informed by multiple factors, Barr said, including the fact that “in 2024, there were multiple competitors, and there aren’t anymore.” Additionally, “we know that this is a massive unmet medical need, and this is a really incredible set of data that we think will be very convincing to the clinical community,” Barr said. Looking ahead to a potential evolution of the COPD treatment landscape, Barr noted that most patients start treatment in the community with an option like a triple therapy, and for them, having an option like AstraZeneca’s inhaler Breztri will remain a “really important part” of that journey. But of the patients uncontrolled on triple therapy, which Barr described as “about half of them today,” just a “small fraction” are currently eligible for biologic therapy, which she emphasized AstraZeneca is working to change. Understanding that COPD is not a “one-size-fits-all” disease, AstraZeneca is also looking at its antibody drug Tezspire for patients with T2-driven disease, and the company continues to think about new mechanisms for tackling COPD through both systemic and inhaled drugs, Barr said.
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Going to any games this season?
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Six decades of politics (but little government)
The first aired episode of “Star Trek,” entitled “The Man Trap,” premiered on September 8, 1966 — 60 years ago today. I’m actually editing a political science fiction issue of The Forum right now, and it’s prompted to me think a lot about the ways that Trek deals with politics and government and what it’s offered us as commentary. The @smotus report is a reader-supported publication. To support this work, please become a paid subscriber. Subscribe The original TV series ran from 1966 to 1969. It had a loyal but modest following, but the audience grew substantially with the series in syndication for years after that. The franchise developed its first motion picture in 1979, followed by five sequels, and then a whole other series of films built around the “Next Generation” series that first aired in 1987. In recent decades, several more TV series have built up around it, including the current “Strange New Worlds,” now in its fourth season. Throughout the past six decades, the franchise has offered us a good many insights into US politics and international relations, although often disguised as science fiction yarns. The original series was largely a Cold War fable, with the United Federation of Planets (a stand-in for the US) perpetually at odds with the Klingon Empire (a stand-in for the USSR). The “Let That Be Your Last Battlefield” episode (1969) posited a planet divided into two races, largely indistinguishable to outsiders, but nonetheless constituting a brutal racial hierarchy. “Patterns of Force” (1968) showed a struggling planet where the leader had attempted to construct a benevolent dictatorship — literally Nazism without bigotry — and found that authoritarianism could not exist apart from hierarchy and oppression. (Relatedly, I’d put “Star Trek VI: The Undiscovered Country,” high on a list of dad films about the end of the Cold War, near “The Hunt for Red October.”) Get 20% off for 1 year Indeed, the original series itself was something of a political statement, with a multi-racial crew running the Enterprise, a diverse and largely peaceful Federation mostly free from want and oppression, and protected by Starfleet, an armed force whose scientific mission was at least as important as its military one. Famously, when Nichelle Nichols wanted to walk away from the role of Uhura on the original series, none other than Martin Luther King, Jr. met with her and urged her to remain on the show, discussing the importance of viewers seeing an intelligent Black woman as part of the command team three centuries hence. Later series in the Trek franchise offered a good deal of political commentary on their own, but probably none as explicitly and incisively as “Deep Space Nine,” which ran from 1993 to 1999. The episodes surrounding the Dominion War, especially the “In The Pale Moonlight” (1998), showed the compromises, sacrifices, and moral rot associated with winning even a just war — probably better than any series would until “Andor” (2022-25). In “Far Beyond The Stars” (1998), Captain Benjamin Sisko is somehow transplanted to the role of a science fiction writer in 1950s New York. The writer is frequently sidelined and his ideas stolen because publishers don’t want to credit a Black writer. Several series have depicted the secretive Section 31 — an unacknowledged black ops security force operating within Starfleet. These episodes often end up using Section 31 as a foil to show the dangers of a lawless group within a lawful society, even (especially) when that group posits itself as essential for everyone else’s freedom to continue. The current “Strange New Worlds” has played with a few political themes. I found the first two seasons of this show among the best that the Trek franchise has produced in decades, but this season and the last have really been struggling for ideas. Yet one interesting thread is the idea that the diplomatic and enlightened leadership style of Captain Christopher Pike will not work in all situations. “A Quality of Mercy” (2022), which I wrote about here, puts Pike in the middle of a battle with a Romulan vessel in an alternate timeline, and finds that Pike’s conciliatory style would actually make a lengthy and deadly war more likely, while a quick and more violent approach might have prevented the war. This season’s opener, “Valles Marineris,” shows a pre-lightspeed civilization locked in a war to the death with a neighboring planet. The idea of an alliance or a federation hasn’t even occurred to them — their ship’s commander is curious but doesn’t see it as an option. For a franchise as political as “Star Trek,” one thing we almost never see is the government. We get occasional glimpses of Starfleet’s council — mostly uniformed people at a rectangular table — but almost no sense of how the Federation is governed. Are there elections? Who is in the legislature? How much power does the president have? What kind of factional divisions do they wrestle with and how? The shows and films are pretty silent on this. We’ve seen a few military tribunals within Starfleet, but little about how civilians deal with crime and injustice. With recent years seeing some of the franchise’s more interesting plot lines and casts, it seems clear that Star Trek is still full of energy and ideas. Given the erosion of American democracy and the reshuffling of the international order, there’s no shortage of material for future shows to comment on. I’m not sure we should toast to 60 more years, but cheers to a show that continues to teach us about ourselves. Share
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