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Cleveland remains in active search of a trade to send …
Cleveland remains in active search of a trade to send …
Fifth Straight Series Loss
San Diego Padres 5 - Cleveland Guardians 0
Browns Expected To Reunite With Three-Time Pro Bowler
The Cleveland Browns are expected to reunite with a three-time Pro Bowl pass rusher.
USS Abraham Lincoln has among lowest mental health case levels: CENTCOM chief
Adm. Brad Cooper praises crew's resilience amid reports of concerns over sailors' well-being, conditions aboard aircraft carrier | Anadolu
How menopause can impact mental health
Dr. Lulu Zhao, a mood disorder specialist at Cleveland Clinic, says during perimenopause, a woman’s hormone patterns can become erratic, which can impact their mental health.
Trump’s vaccine order is counterproductive and ‘wrong on so many levels,’ GOP lawmaker says
GOP Republican Sen. Bill Cassidy called President Donald Trump’s new vaccine order to separate injections for measles, mumps and rubella “wrong on so many levels.”
Intel Reportedly Splits Its Handheld Strategy As A Tiny 4-Xe3 Panther Lake Chip Targets The Budget Buyers Arc G3 Ignored
Intel is preparing a Panther Lake 4+0+4+4 SoC for entry-level gaming handhelds, potentially lowering prices below $800.
Ex-Browns QB Blasts Team Over Handling of Shedeur Sanders
Robert Griffin III criticized how the Cleveland Browns have managed their quarterback battle between Shedeur Sanders and Deshaun Watson. The post Ex-Browns QB Blasts Team Over Handling of Shedeur Sanders appeared first on HEAVY.
Do it Best Group Holds Level-Up Internship Program
Do it Best Group is helping develop the next generation of Northeast Indiana professionals through its 2026 Level-Up Internship Program, an immersive summer experience designed to bridge the gap …
Cleveland Museum of Art plans $40 million restoration of Fine Arts Garden
The project is expected to cost around $40 million to complete.
Browns QB Shedeur Sanders Speaks Out After Brutal INT
Cleveland Browns quarterback Shedeur Sanders explained his brutal interception against the Bears. The post Browns QB Shedeur Sanders Speaks Out After Brutal INT appeared first on HEAVY.
Padres vs Guardians Highlights ⚾️ MLB on FOX
Check out the best highlights between the San Diego Padres and the Cleveland Guardians.
Ben Johnson Sends Blunt Message After Bears’ Blowout Preseason Win
Chicago defeated Cleveland by 24 points, but Ben Johnson was not satisfied with the protection provided by his offensive line.
With measles cases on the rise, doctors stress childhood vaccination
As nationwide measles cases climb to the highest levels seen in 35 years, Lucas County medical practitioners are raising the importance of vaccinating ...
Browns rookie wideout impresses in preseason loss to Bears
A rookie stood out for the Cleveland Browns in their 2026 preseason opener against the Chicago Bears.
Todd Monken: Deshaun Watson functioned at a high level
Watson played in his first game since tearing his Achilles during the 2024 season.
Instant analysis from Bears' 34-10 preseason win vs. Browns
The Chicago Bears dominated the Cleveland Browns, 34-10, in their preseason opener. Here's our instant analysis.
Deshaun Watson throws for 126 yards in 2026 preseason debut
In competition with Shedeur Sanders, Deshaun Watson started the first preseason game for the Browns on Saturday against the Bears and played the entire first half.
Chicago Bears vs. Cleveland Browns Preseason Game Discussion
Chicago Bears vs. Cleveland Browns Preseason Week 1 live game message board and fan discussion.
5 Insightful Analyst Questions From PENN Entertainment’s Q2 Earnings Call
PENN Entertainment delivered results for Q2 that met Wall Street’s revenue expectations and produced a significant upside in non-GAAP earnings per share, prompting a positive market reaction. Management emphasized the strength of the retail casino segment, highlighting record revenues driven by recently completed property development projects and increased demand from mid- and high-value customers. CEO Jay Snowden cited broad-based momentum, noting, “Our best-in-class property level management t
Prediction markets and sports betting: How this UK exchange is trying to do both in the U.S.
Smarkets is entering the U.S. prediction market race but also applying to run as a sportsbook within states amid regulatory uncertainty at the federal level.
The Pandemic Decimated Chicago’s Famous Loop. Now, New Business Openings and $673 Million in Investment Are Fueling Its Recovery
A new report finds office vacancies are leveling off and businesses are filling empty storefronts.
Democratic primary turnout has soared in some states. Can it carry over to November?
Democratic voters are turning out for this year’s primaries at levels not seen in more than 20 years.
Scientists detect a surprising shift in human blood as atmospheric CO2 rises
Rising carbon dioxide in the atmosphere may be leaving a measurable imprint inside the human body. Researchers analyzing more than two decades of U.S. health data found that blood bicarbonate levels have climbed about 7% since 1999, while calcium and phosphorus have declined—changes that closely track increasing atmospheric CO2.
How many rushing yards will Quinshon Judkins have in 2026?
After a solid rookie year, Quinshon Judkins is positioned for a bigger role with the Cleveland Browns’ offense.
Democrats and their big roll of the dice
For Republicans on the ballot this fall, the hand they are forced to play is rather set. Even if so many of them had not so meekly submitted to President Donald Trump’s agenda, they would still be largely tethered to the President’s unpopularity and depth-charge-level approval ratings. On the other hand, Democrats, as the party […]
Fans mourn 4 beloved TV & movie figures who died this week
Jon Cypher, Ben Jones, Tedde Moore and Gloria Kamen are among the beloved entertainment figures and familiar faces fans mourned this week.
FDA upgrades egg recall linked to salmonella to highest health risk level
Will Deshaun Watson Play vs Bears? Browns QB Update
Will Deshaun Watson play vs. the Bears? We're breaking down the Cleveland Browns' QB situation ahead of their first preseason game.
Lamborghini’s flagship Revuelto levels up with SV trim
I can already hear the crypto bros frantically checking their wallets.
Gallery: Baptist Health Walker opens pediatric ER space, reopens NICU services
Baptist Health Walker Hospital has opened a new dedicated pediatric emergency room treatment space and reopened its Level II NICU services.Hospital leaders cut
A sunscreen ‘gamechanger?’ What the science says about bemotrizinol
Stanford Health Care delivers the highest levels of care and compassion. SHC treats cancer, heart disease, brain disorders, primary care issues, and many more.
Henry Ford Providence Southfield Hospital loses Level II trauma status
Henry Ford Health says ambulances can no longer bring trauma patients to its Providence Southfield Hospital because it lost its trauma center status.
Opinion: Cleveland’s enrollment cliff is becoming a talent cliff
"Demography created the enrollment cliff. Immigration policy should not turn it into a talent cliff," attorney Richard T. Herman writes.
Empower Sports brings athletes of all abilities into the game
The Cleveland-based nonprofit brings sports and exercise programs to kids and adults with physical and cognitive disabilities, providing opportunities to have fun and make friends.
Frontier flight declares medical emergency after 4 flight attendants develop headaches, nausea
Four Frontier Airlines flight attendants reported headaches and nausea on the Airbus A321 approaching Fort Lauderdale from Cleveland, prompting a medical emergency call.
West Virginia math and English scores top pre-COVID levels as science slips
West Virginia’s 2026 student assessments show math and ELA proficiency above pre-COVID levels, with math rising to 39% and ELA holding at 48%. Science slipped to 29%, while chronic absenteeism remained strongly linked to lower scores.
Armstrong appoints senior advisor Conner Swanson to lead ND Department of Health and Human Services | North Dakota Office of the Governor
Gov. Kelly Armstrong appointed Conner Swanson to lead the North Dakota Department of Health and Human Services (DHHS), effective Aug. 29, citing his experience with complex policy issues at both the state and federal levels and his guidance to the agency through the Governor’s Office these past two years.
Business owners and residents fed up with frequent power outages in Cleveland's Collinwood neighborhood
Collinwood business owners and residents said they are frustrated with recurring power outages. They said their neighborhood, on Cleveland's East Side, has experienced frequent outages this summer, even with clear skies and no rain.
Beer, wine or liquor? Massive study reveals which was linked to lower death risk
Heavy alcohol use raised death risk by 24%, but wine at low levels was linked to lower mortality than beer or spirits in a UK Biobank study.
Clemson’s Cade Klubnik Gets Honest on Comfortability Heading Into NFL
Former Clemson star quarterback Cade Klubnik opened up about his comfort level as he heads into his rookie season.
WWII motorcycle and soldiers emerge from river muck in Hungary
Historically low water levels in the Danube are revealing over 80 years of history.
4,000 Meters Below Sea Level, Scientists Have Found the Spectacular ‘Dark Oxygen’
What if it could solve all of our energy problems?
Cleveland Fed’s Hammack questions whether U.S. inflation will keep slowing
The Federal Reserve Bank of Cleveland president says more needs to be done to get to the Fed's 2% target for inflation.
High-flying entertainment: Airway X Motocross wraps up Cyber Optics races starting this weekend
Airway X Motocross begins its final two Cyber Optics night races of the season this weekend, with the finale set for Aug. 28-29 and a $10,000 purse for professional riders. The night series features racing for riders of all ages and skill levels.
Base iPhone 18 Tipped to Get These Two Pro-Level Upgrades
The base iPhone 18 model that Apple is expected to release by March 2027 will be equipped with 12GB of RAM, up from 8GB in the iPhone 17, according to analyst Jeff Pu. Pu's latest assessment, if accurate, would see the iPhone 18 gaining the same amount of memory as the iPhone 17 Pro models.
‘It’s as physical as some sports’: Fla. high school marching band students can now earn full P.E. credit
This year, thanks to a new Florida law, high school students can now satisfy both their arts and physical education credits if they're in marching band for two years. WLRN reporters went to Charles W. Flanagan High School in Pembroke Pines to watch students spend long summer days practicing to perform at a high level.
Opinion | Expand training programs for entry-level health care jobs
Hospitals need workers, but colleges can’t accept enough students
Ahead of Bears Clash, Shedeur Sanders Addresses Possible Injury Concern
Cleveland Browns quarterback Shedeur Sanders has been steadily ramping up his preparations for his second NFL season. Sanders was drafted with the 144th overall pick in the fifth round of the 2025 Draft.
Asia-Pacific parliamentarians urge bolder action for universal health coverage, climate resilience and responsible AI
Parliamentarians representing 16 countries from across the Asia-Pacific region concluded the Ninth Meeting of the Asia-Pacific Parliamentarian Forum on Global Health (APPFGH) today, reaffirming their key role in advancing universal health coverage (UHC) amid the risks and opportunities posed by AI and climate change. In adopting the Phnom Penh Communiqué, parliamentarians urged fellow legislators regionwide to strengthen sustainable financing for UHC to widen access to health for all, including the most vulnerable populations; promote responsible governance of AI amid ethical concerns over this fast-evolving technology; and build climate-resilient health systems to anticipate and respond to mounting pressures ranging from rising sea levels in coastal areas to air pollution and other environmental degradation.The National Assembly of Cambodia, with support from Cambodia’s Ministry of Health and the World Health Organization (WHO), hosted the Forum in Phnom Penh from 11 to 13 August 2026 – the first time the Forum has convened in a Mekong country.Parliamentarians urge action to close gaps in accessIn the Communiqué, parliamentarians recognized that at-risk and marginalized groups are the ones most severely affected by gaps in access to health services. These groups include people living in poverty, women and children, persons with disabilities, older people, migrants, refugees, and those in rural, remote or island communities. The Communiqué urges fellow parliamentarians and policy-makers to advocate for laws and policies that support sustainable financing to protect people from financial hardship, with a focus on primary health care, prevention and equity. "The Communiqué is a call to action. It sets out ambitious, concrete measures that deliver meaningful impact on the ground. We are all accountable for advancing universal health coverage and translating our commitments into tangible results. Cambodia is fully committed to advancing UHC, including the promotion of ‘healthy people, prosperous country’ campaign,” said Samdech Maha Rathsapheathika Thipadei Khuon Sudary, President of the National Assembly of the Kingdom of Cambodia.His Excellency Professor Chheang Ra, Minister of Health of the Kingdom of Cambodia, highlighted the need for collaboration beyond the health sector. “Universal health coverage cannot be achieved by the Ministry of Health alone. It requires support, particularly from parliamentarians, across political, legislative, financial, social protection, education, infrastructure, and environmental domains. While each country follows its own path, one factor is universally critical for success: strong governance and leadership. We all believe in this principle, and in our respective political roles, we remain committed to strengthening these key success factors to ensure that no one is left behind.”Promoting responsible AI adoption Parliamentarians acknowledged that, while AI has already demonstrated its ability to improve access to health services and support delivery, careful and ethical governance is necessary to safeguard quality, safety, privacy and public trust. This underscores the importance of parliamentarians in promoting legal and regulatory frameworks addressing liability, records ownership and data governance, while embracing innovation that protects ethical practice.“Without strong governance, safeguards for privacy and data security, sustainable financing, and attention to those most at risk of exclusion, new technologies may widen existing gaps instead of closing them. This is why parliamentarians matter. We pass laws. We approve budgets. We scrutinize government action. We represent communities. We can ask whether health services are reaching rural, remote, ageing, poor, and marginalized populations. We can ask whether innovation is being guided by equity, evidence, and ethics,” said Hon. Man Hee Lee, President of the Asia-Pacific Parliamentarian Forum on Global Health.Building climate-resilient health systemsParliamentarians also reiterated that the climate crisis is a direct threat to people’s health and to achieving UHC more broadly, deepening the same gaps in access already faced by at-risk and marginalized communities. They recognized the need for WHO Member States to ensure sufficient national appropriations and oversight, and for parliamentarians to raise awareness in their constituencies and mobilize local action in building climate-resilient and sustainable health systems.“Universal health coverage, climate change and AI cannot be addressed in isolation. The same communities struggling to access health services today are often the ones most exposed to climate shocks, and most in need of the opportunities AI can offer if this technology is governed responsibly,” said Dr Saia Ma’u Piukala, WHO Regional Director for the Western Pacific. “Having served previously in this Forum myself as a parliamentarian from Tonga, I recognize how the Phnom Penh Communiqué reflects the shared resolve of legislators across the Asia-Pacific region: the laws parliamentarians pass and the budgets they approve help ensure this progress reaches the people who need it most.”As the Forum drew to a close, delegates reflected on what they would carry back to their own parliaments and constituencies.“I wish to share three points here worth carrying home from Phnom Penh: we need to invest in primary health care as the foundation of coverage; we need to remove the barriers that keep people from care, whether financial, geographic or social; and we need to build systems that are inclusive by design, protecting those most at risk of being left behind,” added Hon. Ouch Borith, First Vice-President of the Senate of the Kingdom of Cambodia.###Notes for editors:The Asia-Pacific Parliamentarian Forum on Global Health (APPFGH) is a platform for parliamentarians to exchange ideas, build political will, strengthen capacity and foster collaboration towards sustainable health action. This was the ninth meeting of the APPFGH, with the theme “Universal Health Coverage in the era of Climate Change and Artificial Intelligence”. Target 3.8 of the Sustainable Development Goals calls on countries to achieve universal health coverage, including financial risk protection, access to quality essential health services, and access to safe, effective, quality and affordable essential medicines and vaccines for all. In the Western Pacific, UHC service coverage index (SDG 3.8.1) rose from 63 in 2000 to 81 in 2023 (figures include Indonesia), and roughly one in four people in the Western Pacific have experienced financial hardship (SDG 3.8.2). Progress towards UHC in the Asia-Pacific region remains uneven, with hundreds of millions of people still lacking access to essential health services or facing financial hardship due to health-related expenses. Strengthening the role of parliaments – through legislation, financing and oversight – is central to closing this gap and accelerating progress towards UHC across the region.Parliamentarians participating in APPFGH in Cambodia this week include: Hon. Pehin Dato Adanan YUSOF, Brunei Darussalam; Hon. Rosmawatty ABDUL MUMIN, Brunei Darussalam; Hon. LORK Kheng, Kingdom of Cambodia; Hon. YOS Phanita, Kingdom of Cambodia; Hon. KHOUN Khundy, Kingdom of Cambodia; Hon. HENG Halim, Kingdom of Cambodia; Hon. KHOENG Noupheap, Kingdom of Cambodia; Hon. SENG Nhak, Kingdom of Cambodia; Hon. LY Sukry, Kingdom of Cambodia; Hon. NHOEURN Raden, Kingdom of Cambodia; Hon. Dr Ratu Atonio LALABALAVU, Republic of Fiji; Hon. Vijay NATH, Republic of Fiji; Hon. Man Hee LEE, Republic of Korea; Hon. Dr Jiho CHA, Republic of Korea; Hon. Jonghun BAEK, Republic of Korea; Hon. Youngsuk SEO, Republic of Korea; Hon. Dr Phayvanh KEOPASEUTH, Lao People’s Democratic Republic; Hon. Suhaizan Bin KAIAT, Malaysia; Hon. Dr Perpetua KONMAN, Federated States of Micronesia; Hon. Ganmaa DAVAASAMBUU, Mongolia; Hon. Charmaine SCOTTY, Republic of Naoero; Hon. Vincent Ambance KUMURA, Papua New Guinea; Hon. Dr Edwin CRUZADO, Republic of the Philippines; Hon. AUUAPAAU Mulipola Aloitafua Mulipola, Samoa; Hon. ASIATA TAVUI Tafu Salevao, Samoa; Hon. Dr Alani Petelo TANGITAU, Tonga; Hon. Paul PAOLO, Republic of Vanuatu; Hon. Franklyn Ezra WILLIAM, Republic of Vanuatu.For more information, contact: WHO Regional Office for the Western Pacific: wprocom@who.int National Assembly of the Kingdom of Cambodia (International Relations Department): ir.nacambodia@gmail.com
Is Second-Year Leap Coming For Seahawks' Rashid Shaheed?
Set to become more of a receiver in 2026, is Shaheed about to take his game to a new level in Seattle?
Starting QB Revealed for Browns Preseason Opener with Bears
The Cleveland Browns QB competition reaches it's next phase as the team faces the Chicago Bears in their preseason opener. But who will start?
Duke's digital twin technology could take hemodynamic assessments to a whole other level
Researchers at Duke are hard at work on digital twins that could help care teams make important treatment decisions.
Candidates for Ohio governor outline data center plans
Amy Acton called for a conditional moratorium while Vivek Ramaswamy said he wants free electricity for those near data centers.
NFIB survey: small business optimism continues to rise
Hiring plans hit their strongest level since 2022, even as owners reported stubborn uncertainty and difficulty finding qualified workers.
Tigers seek series-clinching win over Guardians on Wednesday night
The Detroit Tigers took the first game of a critical home series against the Cleveland Guardians on Tuesday night with a narrow 6-4 victory. The good guys got their first win against Tanner Bibee since July 2024 thanks to some well-timed offense, and somehow, Kenley Jansen did not blow the save despite feeding the batters […]
Huge Helldivers 2 Patch Adds New Illuminate Enemies, a New Biome 'Full of Fresh Horrors,' a Level Cap Increase and Much More
Helldivers 2 developer Arrowhead has released a major update for the game, adding new Illuminate enemies, a new biome, and raising the level cap. Check out the 7.0.0 patch notes.
Browns Sign Ex-Eagles Tight End Amid Rookie’s Ongoing Absence
The Cleveland Browns added a new tight end amid uncertainty around the rookie's future. The post Browns Sign Ex-Eagles Tight End Amid Rookie’s Ongoing Absence appeared first on HEAVY.
Is Lemon Juice Good for You? 6 Health Benefits To Know
Lemon juice is packed with vitamin C and other vital nutrients. A registered dietitian shares its health benefits and how to add it to your menu.
Recurring Issues Hurt Cleveland Guardians in Loss to Detroit Tigers
The Cleveland Guardians lost to the Detroit Tigers for the first time during the 2026 season.
Crimson Desert dev comments on status of Nintendo Switch 2 port, targeting first half of 2027
Pearl Abyss has commented again on the Nintendo Switch 2 port of Crimson Desert, providing the most encouraging update we’ve had thus far. In its latest earnings letter, the company said that it’s now “currently playable at a foundational level, and technical evaluations are underway to ensure performance optimization and compliance with our quality standards.” The other piece of important...
Mason Rudolph Doesn’t Hold Back About Former Steelers Coaches
New Pittsburgh Steelers head coach Mike McCarthy has dedicated himself to developing the team’s quarterbacks, which is a welcome sight for Mason Rudolph, who opened up about the lack of tutelage under the previous coaching staff.“He brings a level of expertise that I just have not been around,” Rudolph told reporters, including Gerry Dulac of […] The post Mason Rudolph Doesn’t Hold Back About Former Steelers Coaches appeared first on HEAVY.
Great Lakes Sports & Entertainment Network to air Tigers-Guardians Game 3 Thursday
The Detroit Tigers will play Game 3 of their series against the Gleveland Guardians on Thursday, August 13, and there’s a new way to watch.
Small business optimism rebounds to highest level since Aug. 2025: NFIB
Small businesses last month scaled back both actual and planned price increases for the first time this year, the National Federation of Independent Business said.
Browns offseason once again proving GM Andrew Berry right
The Cleveland Browns 2026 NFL draft class has already shown flashes of being great. Another feather for GM Andrew Berry
Cleveland Cavaliers seek members for dance, drumming teams
The Cavs are holding auditions for three on-court entertainment groups for home games at Rocket Arena.
Former OMB, State Budget Leader Lauren Larson Joining the Bipartisan Policy Center as Executive Vice President for Economic and Health Policy
Washington, DC — Today, the Bipartisan Policy Center announced that Lauren Larson will join the organization as executive vice president of economic and health policy on August 25. Larson brings deep expertise in fiscal and health policymaking at the state and federal levels. She will run the economic policy and health programs and lead the … Continued
U.S. small business sentiment surged to an 11-month high in July as hiring plans jumped
The optimism index climbed 2.4 points to 99.8, surpassing its 52-year average, while planned hiring jumped to its highest level since October 2022
Jenna Ortega Won't Stop Taking Risks, No Matter How Big Wednesday Gets
At twenty-three, Ortega already has a resume a mile long. A sci-fi gamble could vault her to another level entirely.
US Small-Business Optimism Rises to an Almost One-Year High
US small-business optimism rose in July to the highest level in almost a year as firms ramped up hiring plans and inflation pressures eased.
FM bets on structure-level wildfire science with FortressFire acquisition
The deal puts physics-based ignition modeling at the center of FM's commercial property underwriting - and signals where the broader market is heading
Browns’ Demoted Starter Now ‘Fighting’ to Keep Roster Spot
The Cleveland Browns moved rookie Spencer Fano ahead of Dawand Jones at left tackle. Now, Jones is in some trouble. The post Browns’ Demoted Starter Now ‘Fighting’ to Keep Roster Spot appeared first on HEAVY.
Should You Try Ube?
Ube is a vibrant purple yam that packs vitamin C, fiber and antioxidants into every bite. A registered dietitian explains how it can benefit your health.
About a quarter of the Netherlands now sits below sea level, and the obvious explanation is that the sea rose. However, researchers who reconstructed the past thousand years of the Dutch coastal plain concluded the opposite — much of the land came down to meet the water
The Dutch blamed rising seas for their waterlogged land, but a thousand years of geological records tell a different story: the ground itself has been sinking.
Philadelphia Eagles and Dunkin' present $25,000 donation to Leveling the Playing Field
Dunkin’s Annual "Touchdowns for Kids" Program Helps Expand Access to Youth Sports Across Greater Philadelphia
Dunkin' Supports Youth Sports
Dunkin' presented "Leveling the Playing Field" with a $25,000 donation.
New appeals board could mean fines, stronger enforcement for businesses that violate laws, county ordinances
Cuyahoga County established an Administrative Appeals Board, enabling Consumer Affairs to impose fines on businesses violating consumer protection laws rather than just issuing warnings.
Forty Under 40: Devin Kuhl
When Devin Kuhl joined ArcBest nearly 15 years ago as an entry-level graphic designer, he couldn’t have predicted he would one day help redefine how customers interact with the company’s...
Dan Campbell Reveals Jared Goff’s Next Big Step
Dan Campbell says Jared Goff has reached another level as a quarterback, with greater urgency, command and leadership for the Detroit Lions.
The rise of managed intelligence: AI is rewriting the cybersecurity playbook
AI adoption is accelerating. Learn why governance, cybersecurity and executive oversight are essential to reduce risk and scale AI safely.
AbCellera women’s health data top ‘most aggressive upside scenario,’ putting Astellas and Bayer on notice
AbCellera has reported phase 2 results “beyond even the most aggressive upside scenario” that its CEO dared to consider, boosting the biotech’s chances of challenging Astellas and Bayer for a women’s health market. The phase 2 clinical trial compared ABCL635, an antibody targeting NK3R, to placebo in patients with hot flashes caused by menopause. Investigators enrolled 92 postmenopausal women experiencing a mean of about 10 moderate or severe hot flashes per day. By Week 4, the number of moderate or severe hot flashes had fallen by a mean of 8.8 on ABCL635 and by 3.5 on placebo. That statistically significant, placebo-adjusted reduction of 5.3 hit the trial’s primary endpoint. The level of efficacy also cleared the bar set by existing drugs. While cross-trial comparisons can be misleading, AbCellera CEO Carl Hansen, Ph.D., had seen enough to start hyping the program. “We now view ABCL635 as a potential best-in-class non-hormonal therapy with strong differentiation against approved NK3R competitors across all important dimensions, including efficacy, safety, dosing and convenience,” Hansen said on a Monday morning conference call with investors to discuss the data. “We believe ABCL635 is now a highly de-risked program.” Last week, Hansen used AbCellera’s earnings call to set expectations for readout, with the CEO defining success as a clean safety profile and efficacy comparable to the two approved small molecules. The data vaulted over that bar. Astellas linked (PDF) one of the small molecules, Veozah, to placebo-adjusted reductions in hot flash frequency of 2.1 and 2.6 at Week 4 of its two phase 3 trials. Bayer reported (PDF) placebo-adjusted reductions of 3.04 and 3.29 at Week 4 of pivotal studies for its small molecule, Lynkuet. At 5.3, the placebo-adjusted reduction in AbCellera’s trial comfortably cleared the standard set by the incumbents. Veozah and Lynkuet came to market based on evidence of their ability to reduce the frequency and severity of hot flashes. AbCellera’s phase 2 study covered both endpoints, with the Canadian biotech reporting a mean reduction in severity of 1.4 points at Week 4 on ABCL635, compared to 0.3 points for placebo. Again, the placebo-adjusted result compares favorably to data on Veozah and Lynkuet. Analysts shared Hansen’s enthusiasm for the data. The phase 2 results “firmly validate ABCL635 as a potentially best-in-class treatment,” BMO Capital Markets analysts said in a note to investors Monday. ABCL635’s apparent efficacy edge “is likely attributable to the higher dosing/target engagement the asset is able to reach vs. the oral agents due to its wider therapeutic index,” the analysts added. The analysts, who model $2.3 billion in unadjusted peak sales for ABCL635, flagged the safety profile as another positive of the phase 2 readout. While Veozah carries a boxed warning for liver damage, nobody on ABCL635 in the phase 2 trial had elevated liver enzymes or bilirubin values. If replicated in phase 3, the lack of a liver signal could allow approval without the monitoring requirements imposed on Veozah. Investors appeared equally enthused, sending AbCellera's stock up 32% to $9.21 in premarket trading Monday from a Friday closing price of $6.93. Next, AbCellera will collect the Week 12 data and talk to its advisors about further development. The results open up “a wide variety of possibilities of how we might take this forward into phase 3 studies to truly maximize the value of the asset and make sure that ABCL635 is able to demonstrate its differentiation potential,” Sarah Noonberg, M.D., Ph.D., AbCellera’s chief medical officer, told investors.
Peptides talk is everywhere: But what does the science say?
Stanford Health Care delivers the highest levels of care and compassion. SHC treats cancer, heart disease, brain disorders, primary care issues, and many more.
UNCW Business School Students Travel to Prague for Real-Life Consulting Experience by David Glew
This article was contributed by Kestrel Smoot, International Programs Coordinator for UNCW’s Cameron School of Business. During the most recent spring semester, 33 upper-level finance and marketing students from the UNCW’s Cameron School of Business traveled to Prague, Czechia, to participate in an intensive international consulting project. Unlike traditional study-abroad programs, the Prague consultancy project focuses on real client engagement. Each year’s project is entirely new, designed through collaboration between faculty and industry partners to identify a current business challenge that students will address. This year, students worked with MAMS-Champi, a Czech non-alcoholic beverage company that is seeking to expand into other global markets. Throughout the first half of the semester, students attend class at UNCW and prepare for their time abroad by conducting preliminary research, developing analytical frameworks, and organizing themselves into specialized teams responsible for tasks such as marketing strategy, industry analysis, consumer segmentation, and competitive evaluation. The course emphasizes independence and teamwork, requiring students to take ownership of their work, manage deadlines, and collaborate across functional groups. Additionally, faculty serve as advisors, allowing students to navigate the complexities of the project much as they would in a professional consulting environment. Once in Prague, students met with company leadership, toured facilities, and refined their recommendations based on real-time feedback. The in-person component is widely regarded as the most transformative aspect of the program because students must synthesize weeks of work into a cohesive presentation and deliver it to the client, demonstrating professionalism, strategic thinking, and adaptability. Beyond the consulting work, students participated in cultural and educational activities that broadened their understanding of global business environments. They explored Prague’s historic districts, learned about Czech culture, and engaged with local professionals. These experiences helped students understand how economic, regulatory, and social factors shape market opportunities. The Prague consultancy project stands as a defining example of the Cameron School of Business’s commitment to experiential learning, consistently strengthening students’ confidence, enhancing their resumes, and serving as a focal point in job interviews. Employers recognize the value of the hands-on experience and transferable skills students gain, underscoring the program’s role in preparing industry-ready graduates for today’s fast-moving business landscape.
Ford’s new AI assistant can check your fuel levels and tire pressure
Ford is adding Google’s Gemini as a stopgap measure.
Cook County survey seeks input on public health vending machine
Cook County Public Health and Human Services is seeking public input on its public health vending machine initiative. In a survey, the department is asking residents for feedback on what items should be stocked in the machine, where it should be located and their level of support for the initiative. Public health vending machines have...
Cleveland Browns news: Who is ready to choose violence?
The latest Cleveland Browns news and notes from around the NFL in the August 10 edition of the Daily Dawg Chow.
Mirror cells could threaten life on Earth. Why are we building them?
For people with two hands, one is usually dominant. On a molecular level, earthly life takes this to the extreme. All of the DNA in living things twists to the right, whereas the protein building blocks favor a kind of left-handed chemistry.The rules of life are based on this chemistry.In recent years, scientists have worked toward a kind of mirror version of life. Currently, the technology doesn't exist to make mirror life at the cellular level — and likely won't for at least a decade. Still, a group of scientists is concerned enough about the possibility that they've published a 299-page technical report calling for a stop to the science.In this encore episode for our Tech Camp series, host Regina Barber talks to Carl Zimmer, a science reporter at The New York Times, about his reporting on mirror cells — and why creating them could lead to devastating consequences for life on Earth.Check out Carl's full article.Curious about other controversial research? Email us at shortwave@npr.org.Support public media with NPR+ and enjoy perks for over 25 podcasts like this one. This show’s perks include sponsor-free listening. Learn more at plus.npr.org.
Shedeur Sanders Breaks Silence After Browns Demotion
Shedeur Sanders delivered a message after his recent demotion with the Cleveland Browns. The post Shedeur Sanders Breaks Silence After Browns Demotion appeared first on HEAVY.
Bronchiectasis: How To Manage Your Mental Health and Stay Connected
If daily symptoms and flares take their toll on your mental health, you’re not alone. A pulmonologist shares how to cope and manage.
How Does Your Samsung Galaxy Watch Measure Antioxidant Levels?
You might not know this, but your Samsung Galaxy smartwatch has a function to measure your antioxidant levels, which it does with special LEDs.
Passing the torch: Cleveland’s next generation of small-business owners may already be here
Cleveland’s population has fallen 60% in the past 75 years. As currents business owners approach retirement, Richard T. Herman presents a succession strategy involving the next generation.
Strengthening Indonesia’s health emergency response through after action review of disaster response in Aceh, North Sumatra and West Sumatra
Severe floods and landslides that struck Aceh, North Sumatra and West Sumatra in late 2025 exposed both the strengths and gaps in Indonesia’s health emergency response, prompting a nation-wide effort to strengthen preparedness for future crises. In the early phase, the scale and speed of the crisis challenged coordination, data systems and surge capacity. To assess the response, the World Health Organization (WHO) Indonesia supported the Ministry of Health’s Center for Health Crisis in conducting a multi-stakeholder after-action review (AAR). The review brought together government agencies, health sub-clusters, NGOs, and partners. “The AAR is a critical process for strengthening our collective response capacity,” said Agus Jamaludin, Head of the Center for Health Crisis at the Ministry of Health. “It provides valuable lessons not only for the Health Crisis Center but also for all stakeholders involved and serves as an important reference for improving future responses across regions.” After Action Review (AAR) brought together key stakeholders to reflect on the emergency response, identify lessons learned, and strengthen preparedness for future health crises. (WHO/Resty Armis)Through structured discussions across four pillars – leadership and governance, information-based decision-making, service delivery and resource management – the AAR identified several strengths. These included the rapid mobilization of national surge capacity, such as health reserve workforce (tenaga cadangan kesehatan) and emergency medical teams (EMT) and the continued provision of essential health services in affected areas. At the same time, the review highlighted challenges. Among them were uneven functionality of Health Emergency Operation Center (HEOC), fragmented early data reporting and reactive logistics deployment. The findings informed five strategic priorities for strengthening the system, including HEOC standardization, integration of the One Crisis Data system, establishing disaster-resilient hospitals and reforming surge capacity mechanisms. The AAR demonstrates that Indonesia’s health emergency response has strong foundations but requires system-level strengthening to shift from reactive to proactive preparedness. By mainstreaming the strengths and recommendations identified, Indonesia can build a faster, more coordinated and more resilient health system – better equipped to protect communities during future crises. Written by Lintang Sibarani, NPO Emergency and Humanitarian Actions, WHO Indonesia
At colleges, the AI boom means everyone wants to dabble in computer science
Hiring for entry-level software developers has slowed, and college enrollment in computer science is declining. However, interest in artificial intelligence is growing among students from non-tech majors. Schools like VCU
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The Reason Why Data Center GPUs Have Such Short Lifespans
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Wine, beer, or spirits? Massive study finds a surprising health divide
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GungHo Online Entertainment (TSE:3765) P/E Premium Clashes With Shrinking Margins
GungHo Online Entertainment stock came into this earnings release with a muted setup, slightly weaker over the past week but modestly higher over the past month. The headline today is not a revenue story. It is the squeeze between a rich P/E of 52.1x and a thin 2.5% trailing net margin that keeps slipping from the 5.8% level a year earlier. The market is being asked to pay up for future growth while living with weaker profitability and a dividend yield of 3.77% that is not well covered. That...
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