SCROLL NEWS / DISCOVERY

Search headlines

Find the stories shaping the conversation.

Search mode
Refine results
Active filters Keyword All time

Results for " Here " 21,208 found 🔀 AI-powered Shuffle

Detroit Tigers' Opening Day be on cable TV? Here's what we know

The Detroit Tigers haven't been able to give details on their broadcast service, Detroit SportsNet, and its status on cable TV packages.

freep.com logo
Mar 23 • 6:59 PM EDT • Sports • freep.com
Deep dive
😐 Neutral (9%)
wow
55%
love
45%
Miami starts cutting property tax rebate checks for seniors

'This program is about delivering real relief where it matters most.'

floridapolitics.com logo
Mar 23 • 6:43 PM EDT • Politics • floridapolitics.com
😐 Neutral (12%)
ahah
60%
love
20%
wow
20%
“Moana” in live-action: See all the animated characters coming to life in new movie

Moana, Maui, Te Kā... the gang's all here.

malaysia.news.yahoo.com logo
Mar 23 • 6:20 PM EDT • Entertainment • malaysia.news.yahoo.com
NASA Data Hackathon Inspires Community Action

On Jan. 31, students, library staff, researchers, and community members gathered at the University of Florida’s (UF) Marston Science Library for the

science.nasa.gov logo
Mar 23 • 5:30 PM EDT • Science • science.nasa.gov
Travis Kelce reportedly re-ups with Chiefs on a 3-year, $54.7 million deal, but there's a catch
sports.yahoo.com logo
Mar 23 • 3:55 PM EDT • Sports • sports.yahoo.com
Chicago Comic & Entertainment Expo Extra Service

To accommodate passengers attending the Chicago Comic and Entertainment Expo (C2E2) taking place March 27-29, 2026, at McCormick Place, the South Shore Line will be offering extra train service on Saturday, March 28. As McCormick Place is not a scheduled stop, passengers traveling to C2E2 should purchase tickets for Museum Campus. MCCORMICK PLACE SERVICE: Please click here for special […]

mysouthshoreline.com logo
Mar 23 • 3:53 PM EDT • Entertainment • mysouthshoreline.com
Here, There And Everywhere, Blueshirts And NHL
sports.yahoo.com logo
Mar 23 • 3:52 PM EDT • Sports • sports.yahoo.com
NMSU’s ‘Big Bang Bash’ invites community to hands-on art and science experience

New Mexico State University’s College of Arts and Sciences welcomes kids of all ages to this year’s “Big Bang Bash: Where Arts and Sciences Collide” from 5:30 to 8:30 p.m. Thursday, April 2 at...

newsroom.nmsu.edu logo
Mar 23 • 3:48 PM EDT • Science • newsroom.nmsu.edu
Science Through Shadows: How Astronomical Alignments Reveal the Universe

When one celestial object passes in front of another, it can cast a shadow that travels across space – and sometimes across Earth. These moments of alignment, known as eclipses, occultations, and transits, allow scientists to study distant objects in remarkable ways. By observing how light changes when an object briefly blocks another, astronomers can measure sizes and shapes, detect atmospheres, and refine the orbits of asteroids and planets.

science.nasa.gov logo
Mar 23 • 3:47 PM EDT • Science • science.nasa.gov
Deep dive
😐 Neutral (17%)
ahah
73%
wow
27%
Apple has six new products that could launch soon, per rumors

Apple has already launched many new products this year, but rumors indicate there are another six product debuts that could happen soon.

9to5mac.com logo
Mar 23 • 3:07 PM EDT • Technology • 9to5mac.com
No health insurance? Here are other ways to access affordable health care in Alaska

Around 25,000 Alaskans are facing skyrocketing insurance costs in 2026. So we found some other options for accessing affordable care.

alaskapublic.org logo
Mar 23 • 2:13 PM EDT • Health • alaskapublic.org
Uplifting and Not Ceding Ground on Health Equity Practice Is Critical to Strengthening Public Health and the Health of the Nation

Public health science gains in the last quarter century in the United States have been formidable due to a focus on structural and social determinants of health, thereby enhancing understanding of the role of inequitable policies in shaping health inequities and inequitable access to ameliorative resources.

milbank.org logo
Mar 23 • 1:54 PM EDT • Health • milbank.org
Antarctica could warm 1.4 times faster than the rest of the Southern Hemisphere in the coming decades, study finds

Antarctica could warm much faster than its surroundings over the next few decades due to a phenomenon known as polar amplification that is well established in the Arctic.

livescience.com logo
Mar 23 • 12:13 PM EDT • Science • livescience.com
Saturn Gets 11 New Moons, Bringing Its Total To A Whopping 285 –66 Percent Of All The Solar System's Moons

There's actually a rule which stops these moons from being given proper names. Don't give them the attention.

iflscience.com logo
Mar 23 • 11:48 AM EDT • Science • iflscience.com
2026 MLB standings predictions: Expert picks for every division, full projections as baseball season begins

Here are the predictions from our CBS Sports MLB staff for the 2026 season

cbssports.com logo
Mar 23 • 11:00 AM EDT • Sports • cbssports.com
2026 Eagles mock draft roundup 5.0: Just a month away

We’re just a month away from the start of the 2026 NFL Draft. Here are some options for the Eagles.

nbcsportsphiladelphia.com logo
Mar 23 • 10:59 AM EDT • Sports • nbcsportsphiladelphia.com
Microsoft Realizes It’s Epically Screwed Up Windows 11 as Users Rage at Copilot AI Crammed Everywhere

Windows VP Pavan Davuluri effectively admitted outright that the company went too far to shove AI down users' throats at all costs.

futurism.com logo
Mar 23 • 10:45 AM EDT • Technology • futurism.com
Why Kyle Shanahan believes Mike Evans, Christian Kirk picked 49ers over others

Veteran wide receivers Mike Evans and Christian Kirk could have made more money elsewhere, but there was a common reason why they picked the 49ers.

nbcsportsbayarea.com logo
Mar 23 • 10:34 AM EDT • Sports • nbcsportsbayarea.com
Supreme Court hears arguments in mail-in voting case

The Supreme Court is hearing arguments today in a case about whether states may count mail-in ballots received after Election Day. Follow here for live updates.

cnn.com logo
Mar 23 • 9:36 AM EDT • Politics • cnn.com
Deep dive
😐 Neutral (17%)
ahah
52%
wow
48%
Exclusive: Prenuvo expands full-body MRI protocol. What's new?

Prenuvo is launching a new bloodwork component to complement its full-body MRIs. Here's what to know.

usatoday.com logo
Mar 23 • 9:00 AM EDT • Health • usatoday.com
Feature: Where The Heck Do You Start If You've Never Played Resident Evil?

Enter the world of survival horror

nintendolife.com logo
Mar 23 • 9:00 AM EDT • Technology • nintendolife.com
Sewing And Munro Continue Dominance In New Global Sports Alliance International Pickleball Tour With Two Golds In Vietnam

The third event of the new Global Sports Pickleball Alliance saw the tour head to Ho Chi Minh City over the weekend, where Jack Munro and Sofia Sewing both won two golds.

forbes.com logo
Mar 23 • 8:48 AM EDT • Sports • forbes.com
Govee’s Outdoor Chromatic String Lights Sound Obnoxious in the Best Way

These smart light bulbs support Matter, but there's a catch.

gizmodo.com logo
Mar 23 • 8:00 AM EDT • Technology • gizmodo.com
How Healthy Are Meat Sticks and Jerky as Protein Sources?

These convenient snacks are rich in protein and low in calories, but they are considered processed meats. Here's how often you should eat them.

health.com logo
Mar 23 • 8:00 AM EDT • Health • health.com
Data Is at the Heart of What Public Health Does

Data is key to protecting the health and safety of a community, from identifying and tracking disease outbreaks to ensuring that water is safe to drink. Data is also vital to understanding where resources are most needed. This value is especially apparent to the officials charged with protecting public health, such as Dr. Janet Berreman, Kauai’s (Kauaʻi’s)* district health officer.

pew.org logo
Mar 23 • 8:00 AM EDT • Health • pew.org
Here are nearly 100 local high school spring sports stars to watch

Spring sports are rich with talented athletes. From baseball to track and soccer to swimming, here are nearly 100 Fort Collins-area stars to watch.

coloradoan.com logo
Mar 23 • 7:15 AM EDT • Sports • coloradoan.com
😐 Neutral (23%)
wow
78%
ahah
22%
Companies Aren’t Ripping Out Business Software for AI. Here’s What They’re Doing Instead.

Tech leaders at large corporations say that, for now, they’re vibe-coding their own small, custom apps, and putting pressure on their software vendors.

wsj.com logo
Mar 23 • 7:00 AM EDT • Business • wsj.com
There’s little information about a large measles outbreak in Florida, so we went to see it

One of the largest measles outbreaks the US has seen in decades erupted at Ave Maria University in Florida, but very little information was being shared with the public. So CNN went to the small Florida town to learn what’s driving the case count.

cnn.com logo
Mar 23 • 6:00 AM EDT • Health • cnn.com
How ‘Tiny Shortcuts’ Are Poisoning Science

Seemingly harmless data tweaks are undermining the integrity of the entire field. We must define the problem to prevent it.

thereader.mitpress.mit.edu logo
Mar 23 • 5:55 AM EDT • Science • thereader.mitpress.mit.edu
Where to watch South Carolina vs. USC in March Madness Second Round: Time, TV Channel

The No. 1 South Carolina Gamecocks face the 9 USC Trojans in the Second Round of the women's NCAA Tournament. Here's how to see all the action.

usatoday.com logo
Mar 23 • 5:08 AM EDT • Sports • usatoday.com
Deep dive
😐 Neutral (9%)
love
58%
wow
42%
An end to the battle between touchscreens and long fingernails is on the horizon

Anybody who has tried to use a smartphone or tablet with long nails knows that there's a learning curve. Rather than effortlessly tapping with a fingertip, you must awkwardly lay the pads of your fingers ...

phys.org logo
Mar 23 • 5:00 AM EDT • Technology • phys.org
A new twist on matter? Strange 'Half-Mӧbius' molecule has rare properties chemists have never seen before

Chemists created a strange 'half-Mӧbius' molecule, where electrons twist freely out of place to make a continuously looping surface.

livescience.com logo
Mar 23 • 5:00 AM EDT • Science • livescience.com
Coeur d'Alene's science guy

Ahead of his retirement in May from the teaching staff at Arizona State University, behavioral neuroscientist Brian Smith has put his focus into making science more accessible to more people. “There's a lot of misunderstanding what science is,” Smith said.

cdapress.com logo
Mar 23 • 4:08 AM EDT • Science • cdapress.com
😐 Neutral (13%)
Where There’s Wildfire Smoke, There’s Poor Mental Health

Research has increasingly connected wildfire and smoke with worsening mental health, partly due to damage in the brain.

undark.org logo
Mar 23 • 3:46 AM EDT • Health • undark.org
Those who cannot live without wild things

Aldo Leopold wrote in his Sand County Almanac, “There are some who can live without wild things and some who cannot.” The collection of essays first published in 1949 was accepted by a publishing house after a steady stream of rejections. His work long outlived him as Leopold died of a heart attack while fighting […]

coloradopolitics.com logo
Mar 23 • 2:30 AM EDT • Politics • coloradopolitics.com
Devin Booker gets 100% on Suns’ playoff seeding chase

Devin Booker knows where the Suns sit amid their previous five-game skid and how it impacts the playoff seeding chase.

sports.yahoo.com logo
Mar 23 • 1:30 AM EDT • Sports • sports.yahoo.com
Today's NYT Connections: Sports Edition Hints, Answers for March 23 #546

Here's today's Connections: Sports Edition answer and hints for groups. These clues will help you solve The New York Times' popular puzzle game, Connections: Sports Edition, every day.

cnet.com logo
Mar 23 • 12:39 AM EDT • Sports • cnet.com
Students Learn the Science of Tree Felling at Treehaven

Click here to view this video from wjfw.com.

wjfw.com logo
Mar 22 • 11:25 PM EDT • Science • wjfw.com
Precision Nutrition: Tufts University Expert Q&A On How Personalized Diet Science May Transform Health - Where The Food Comes From

Tufts expert José Ordovás explains precision nutrition and how personalized diet science could transform health and prevent disease.

wherethefoodcomesfrom.com logo
Mar 22 • 10:00 PM EDT • Science • wherethefoodcomesfrom.com
A DNA test ruled him out. He was convicted of murder anyway.

Forensics has its share of high-profile problems. There’s phony “junk science,” like bogus bite-mark and blood spatter analyses that have sent innocent people to jail. And there’s the steady drumbeat of lab scandals, where analysts make up results. But there’s a subtler and more pervasive problem at work in many cases: lab analysts and lawyers who take perfectly legitimate science and twist it. Globe Opinion is exploring these distortions with a series we’re calling “Twisted Science.” And there may be no better place to start than with the case of Terrel Barros.

bostonglobe.com logo
Mar 22 • 9:57 PM EDT • Science • bostonglobe.com
Spring Health Fair delivers commitment to student wellness

The Student Wellness Advisory Committee hosted their annual Spring Health Fair on Friday afternoon where students were able to gain free tote bags, learn from live simulations and gain insight on new clubs and organizations centered on wellness.

ndsmcobserver.com logo
Mar 22 • 8:00 PM EDT • Health • ndsmcobserver.com
How the G.O.P. and Democrats Are Talking About the Surge in Gas Prices

Republicans have largely been on defense against Democratic criticism. Here are five arguments advanced by figures in both parties.

nytimes.com logo
Mar 22 • 6:58 PM EDT • Politics • nytimes.com
Two-thirds of workers are burned out—here's what science says about how to tackle it

Burnout is at an all-time high, with some studies saying two-thirds of employees now cite job burnout as a major challenge. Overwork and chronic stress do not just drain energy, they can erode health, ...

phys.org logo
Mar 22 • 6:30 PM EDT • Science • phys.org
Sunday Sports: Sackets hoops in the state finals, plus updates on SU sports

Here’s a recap of your North Country sports this Sunday.

wwnytv.com logo
Mar 22 • 6:20 PM EDT • Sports • wwnytv.com
Nasal swab may catch Alzheimer's disease earlier — here's how it works
nypost.com logo
Mar 22 • 3:48 PM EDT • Health • nypost.com
😐 Neutral (10%)
wow
39%
ahah
38%
love
23%
CBS analyst picked against Purdue basketball. Here's what he thinks of Sweet 16 vs Texas

Boilermakers fans were critical of Seth Davis for his pick proven wrong after Purdue beat Miami. Here's what he thinks of the Sweet 16 game vs Texas.

indystar.com logo
Mar 22 • 3:15 PM EDT • Sports • indystar.com
Deep dive
😐 Neutral (11%)
love
69%
wow
31%
Two Offseason Trades Patriots Should Have Made But Didn't

Here are two trades that the New England Patriots should have pursued this offseason but ultimately passed on.

sports.yahoo.com logo
Mar 22 • 3:07 PM EDT • Sports • sports.yahoo.com
Welcome to allergy season. Here's how to protect yourself

Where you live, what you're allergic to and your lifestyle can make a big difference when it comes to the severity of your allergies.

abc7ny.com logo
Mar 22 • 2:47 PM EDT • Health • abc7ny.com
Goodyear 400 Live Updates, Leaderboard: Will Tyler Reddick Win 4th Race This Season?

Follow along here for live updates from Sunday's Goodyear 400.

foxsports.com logo
Mar 22 • 2:30 PM EDT • Sports • foxsports.com
Your Thymus and Your Healthspan

Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.

erictopol.substack.com logo
Mar 22 • 2:18 PM EDT • Health • erictopol.substack.com
Syracuse finalizing Gerry McNamara hire: Siena coach helped lead Orange to 2003 national championship

McNamara just finished guiding Siena to the NCAA Tournament, where it almost upset No. 1 Duke

cbssports.com logo
Mar 22 • 2:15 PM EDT • Sports • cbssports.com
Are spring temperature swings hurting your health? Yes, here's how

Weather swings affect your physical health in a variety of ways.

delawareonline.com logo
Mar 22 • 1:42 PM EDT • Health • delawareonline.com
😐 Neutral (8%)
wow
60%
love
40%
Everything you need to know about the ‘Hannah Montana 20th Anniversary Special’ — How to watch, premiere time, who’s coming back and more

Sweet niblets! Hannah Montana is back for an anniversary special. Here's what to know.

yahoo.com logo
Mar 22 • 12:00 PM EDT • Entertainment • yahoo.com
Why Small Process Changes Often Deliver the Biggest Business Results

Founders often overlook small operational frictions that drain productivity. Here is how small process improvements can unlock boost scaling.

inc.com logo
Mar 22 • 11:00 AM EDT • Business • inc.com
Science Central: Planetarium opens this week

Wednesday at 10:30 there will be a ribbon cutting unveiling the 1,830-square-foot planetarium features a 21-foot-high, 28-foot-wide dome.

wane.com logo
Mar 22 • 10:37 AM EDT • Science • wane.com
Readers Respond to Health Insurance Chaos for Providence Customers

“Only other questions I have is who is starting the class action and where can I sign up?”

wweek.com logo
Mar 22 • 10:03 AM EDT • Health • wweek.com
iPad 12 With A18 Chip for Apple Intelligence is 'Still Coming This Year'

Apple has updated a wide range of products and accessories this month, but there is still no entry-level iPad 12 with Apple Intelligence support. Fortunately, Bloomberg's Mark Gurman today said an iPad with an A18 chip for Apple Intelligence is "ready to go" and "still coming this year". An earlier report from Macworld claimed that the iPad 12 will actually have an A19 chip.

macrumors.com logo
Mar 22 • 9:56 AM EDT • Technology • macrumors.com
I took an in-person Peleton class with Jess King. Here's how it went.

I took an in-person Peloton cycling class with Jess King. I liked how thought-out the experience was.

businessinsider.com logo
Mar 22 • 9:42 AM EDT • Business • businessinsider.com
Tantalizing Tech: The Goodies at Cyclingworld Europe 2026

Turbulence at Eurobike has led to a big boost for Cyclingworld. Here's some of the latest dream tech from the show.

velo.outsideonline.com logo
Mar 22 • 8:45 AM EDT • Technology • velo.outsideonline.com
Oscar-Winning Alumnus Returns to Pasadena’s ArtCenter for Entertainment Design Expo

One week after winning the Academy Award for Best Animated Feature, KPop Demon Hunters co-director Chris Appelhans returns today to ArtCenter College of Design, the Pasadena campus where he studied illustration, for the college’s third annual Entertainment Design Expo. The expo, known as ENTX, opens the Hillside Campus to the public for a full day of gallery exhibitions, game playtesting, animation screenings and interactive experiences featuring work from more than 200 ArtCenter students and alumni. General admission is free with advance registration. Two industry panels — including Appelhans’s talk — require $15 tickets. Appelhans, who graduated from ArtCenter with a bachelor of fine arts in 2002, co-directed KPop Demon Hunters with Maggie Kang. The animated film, produced by Sony Pictures Animation and released on Netflix, became the streaming platform’s most-watched film in history, according to Netflix, and swept awards season with wins at the Golden Globes, the Annie Awards and the Grammys before taking the Oscar on March 15. His talk and audience Q&A is scheduled from noon to 1 p.m. in the Ahmanson Auditorium. Doors open at 11:30 a.m. The film’s ArtCenter ties extend beyond its co-director. Art director Angela Sung, cinematographer Gary H. Lee, visual development artist Celine Kim and painter Simon Baek are all ArtCenter graduates who worked on the production, according to the college. The free portions of ENTX include a concept design showcase, a production design gallery, a model gallery, a stop motion studio preview, an alumni gallery and a KPop Demon Hunters fan art gallery. Visitors can also playtest games designed by ArtCenter students. An Animation Shorts Showcase runs from 2 to 3 p.m. and includes “Boy, I’m Scared,” a capstone short by ArtCenter graduate Lindsey Tenaglia that was named a semifinalist for the 2025 Student Academy Awards in the animation category. Also screening

pasadenanow.com logo
Mar 22 • 8:30 AM EDT • Entertainment • pasadenanow.com
4 tips for buying a home in a tough market, from the Property Brothers

Drew and Jonathan Scott, AKA The Property Brothers, have a new HGTV show where they guide buyers in a tough market. Here are their best tips.

businessinsider.com logo
Mar 22 • 8:14 AM EDT • Business • businessinsider.com
Core operating profit rises 4% as net profit holds steady, with full-year dividend maintained at HK35 cents

March 22, 2026 -- The Hong Kong and China Gas Company Limited (stock code: 0003, hereinafter referred to as “the Group”) has announced its 2025 ...

markets.businessinsider.com logo
Mar 22 • 8:07 AM EDT • Business • markets.businessinsider.com
Gen Z really, really loves China's trains

This is a condensed version of Business Insider Today, a newsletter that gives you a look at the week’s top stories. Sign up here to get the full Business Insider Today in your inbox every day for the top stories in markets, tech, and business.

linkedin.com logo
Mar 22 • 8:00 AM EDT • Business • linkedin.com
Deep dive
😐 Neutral (21%)
ahah
46%
love
27%
wow
27%
AI was everywhere at gaming’s big developer conference

Developers say it removes the craft from making games.

theverge.com logo
Mar 22 • 8:00 AM EDT • Technology • theverge.com
Why mosquitoes always find you and how they decide to attack

Scientists have finally cracked how mosquitoes decide where to fly—and it’s not by following each other. Instead, each insect independently reacts to visual cues and carbon dioxide, zeroing in on humans when both signals align. Dark colors and CO2 together create the strongest attraction, triggering swarming and biting behavior. This insight could reshape how we design traps and prevent mosquito-borne diseases.

sciencedaily.com logo
Mar 22 • 8:00 AM EDT • Science • sciencedaily.com
Deep dive
😐 Neutral (8%)
wow
70%
ahah
30%
I left Goldman Sachs to build a small baking business. Here's how my time at the firm is giving me a leg up.
yahoo.com logo
Mar 22 • 7:53 AM EDT • Business • yahoo.com
Inflatable homes on the Moon? Scientists reveal how humans could live there sooner than expected - Futura-Sciences

How could humans live on the Moon? Although the Artemis program has taken a more cautious approach following recent delays, the goal remains the same: send astronauts back to the lunar surface. Doing so will require systems that allow crews to stay there for several days, or even several weeks....

futura-sciences.com logo
Mar 22 • 7:00 AM EDT • Science • futura-sciences.com
A tribute to Scott Ostler, columnist, colleague, friend and sports wit

In Bruce Jenkins’ experience, there was never a teammate quite like fellow San Francisco Chronicle columnist Scott Ostler, who retired last week.

sfchronicle.com logo
Mar 22 • 7:00 AM EDT • Sports • sfchronicle.com
Owners of Peoria business are selling it. Here's why

This Manual graduate has been trying to sell his Peoria business for about two years. Now, he has found a prospective buyer.

pjstar.com logo
Mar 22 • 6:20 AM EDT • Business • pjstar.com
😐 Neutral (21%)
love
50%
wow
50%
Project Hail Mary is packed with hard science

The movie “Project Hail Mary” stars Ryan Gosling as a reluctant astronaut on a mission to save Earth. Here’s the science that the movie gets right.

earthsky.org logo
Mar 22 • 6:12 AM EDT • Science • earthsky.org
Deep dive
😐 Neutral (18%)
wow
54%
ahah
46%
I'm glad my daughter was rejected from an Ivy League college

My daughter had her sights set on Brown University, but the Ivy League rejected her. Thankfully, she went to Fordham where she found her true passion.

businessinsider.com logo
Mar 22 • 6:07 AM EDT • Business • businessinsider.com
Former, current NBA players sound off on NBA expansion as vote looms

The NBA is moving closer towards expanding to Las Vegas and Seattle. Here's what players think about the move.

usatoday.com logo
Mar 22 • 6:03 AM EDT • Sports • usatoday.com
FYI BR: Here are the upcoming Holi and Easter festivities in Baton Rouge

Plan for pictures with the Easter Bunny, festivities at the LSU Rural Life Museum and more.

theadvocate.com logo
Mar 22 • 6:00 AM EDT • Entertainment • theadvocate.com
😐 Neutral (0%)
AI-generated ads are trickling into political campaigns, sparking big worries

AI usage in political ads is largely regulated at the state level, but there remain concerns about how they can mislead voters.

nbcnews.com logo
Mar 22 • 6:00 AM EDT • Politics • nbcnews.com
High-Signal Publisher
Where to watch Minnesota vs. Ole Miss in March Madness Second Round: Time, TV Channel

The No. 4 Minnesota Golden Gophers face the 5 Ole Miss Rebels in the Second Round of the women's NCAA Tournament. Here's how to see all the action.

usatoday.com logo
Mar 22 • 5:06 AM EDT • Sports • usatoday.com
Deep dive
😐 Neutral (6%)
wow
54%
love
46%
Where to watch Duke vs. Baylor in March Madness Second Round: Time, TV Channel

The No. 3 Duke Blue Devils face the 6 Baylor Bears in the Second Round of the women's NCAA Tournament. Here's how to see all the action.

usatoday.com logo
Mar 22 • 5:06 AM EDT • Sports • usatoday.com
Deep dive
😐 Neutral (5%)
wow
54%
love
46%
Where to watch Oklahoma vs. Michigan State in March Madness Second Round: Time, TV Channel

The No. 4 Oklahoma Sooners face the 5 Michigan State Spartans in the Second Round of the women's NCAA Tournament. Here's how to see all the action.

usatoday.com logo
Mar 22 • 5:06 AM EDT • Sports • usatoday.com
Deep dive
😐 Neutral (6%)
wow
54%
love
46%
The war on Iran is in its fourth week. Here’s what to know

Three full weeks of the war the US and Israel launched against Iran have shocked the world oil market, pierced a sense of safety in parts of the Middle East, and claimed the lives of US service members and civilians in multiple countries.

cnn.com logo
Mar 22 • 4:00 AM EDT • Politics • cnn.com
Deep dive
😐 Neutral (7%)
wow
38%
ahah
32%
angry
30%
How crowd-control agents can affect health

Grieving mother Naomi White walked along Kennywood Boulevard on March 15 with dozens of friends and family members who had gathered to call attention...

post-gazette.com logo
Mar 22 • 4:00 AM EDT • Health • post-gazette.com
😐 Neutral (5%)
wow
34%
ahah
33%
love
33%
Eating More Ultra-Processed Foods Could Damage Your Bones. Here's Why

Eating higher amounts of ultra-processed foods is associated with lower bone mineral density and a higher risk of hip fractures, even in younger adults under 65.

healthline.com logo
Mar 22 • 3:33 AM EDT • Health • healthline.com
Jacob Devaney: Man United loanee puts in midfield masterclass

Manchester United had six players in loan action on Saturday afternoon.To find out where all of Manchester United’s loanees are plying their trade this season, click hereEthan EnnisEnnis played the ...

sports.yahoo.com logo
Mar 22 • 3:10 AM EDT • Sports • sports.yahoo.com
Deep dive
😐 Neutral (18%)
wow
71%
love
29%
How “Feeling Over Facts” Reshaped American Politics—from Gingrich to Trump

There was a moment in the 2016 presidential campaign that, in retrospect, sounds less like campaign chatter than something a post-modern French philosopher might have slipped into American politics.

arkansasonline.com logo
Mar 22 • 3:01 AM EDT • Politics • arkansasonline.com
Deep dive
😐 Neutral (11%)
ahah
66%
wow
34%
OPEN THREAD

The Daily Merengue is a place where you can feel free to discuss all things football. Do not be alarmed by the overt RMCF bias. It’s in the name! Shoutout to the mods who do a fantastic job Kung_Fu_Zizou, Juninho, NeRObutBlanco, Felipejack, Ezek Ix and yours truly, Valyrian Steel. Gameday!! Huge clash in the context […]

sports.yahoo.com logo
Mar 22 • 2:39 AM EDT • Sports • sports.yahoo.com
The Antidote to Our Growing Crises Must Transcend Politics

Each day, the challenges in our nation pile up. In just recent weeks, there has been the ongoing war in Iran and the Middle East, and ongoing debates about the growing negative impact of the Internet, looming AI challenges, and the Epstein files. The anticipation of divisive, even ugly, midterm elec...

thefulcrum.us logo
Mar 22 • 1:40 AM EDT • Politics • thefulcrum.us
😐 Neutral (0%)
Are pretzels a healthy snack? Here's what dietitians say

Pretzels are a classic snack food, but are they good for you? Dietitians break down the nutrition content of pretzels and share the healthiest types.

nbcphiladelphia.com logo
Mar 22 • 12:52 AM EDT • Health • nbcphiladelphia.com
Elon Musk uveils moonshot Terafab project. Here are 4 takeaways.

Elon Musk said his Terafab project, a joint Tesla and SpaceX chip manufacturing initiative, will be needed to unlock a terawatt of AI computing power.

businessinsider.com logo
Mar 22 • 12:15 AM EDT • Business • businessinsider.com
🙂 Positive (50%)
France Is Voting for Thousands of New Mayors. Here’s Why It Matters.

The far-right party had first-round successes in several cities, but so did the far left. Sunday’s second round may clarify who has real momentum.

nytimes.com logo
Mar 22 • 12:01 AM EDT • Politics • nytimes.com
Bloodstained: The Scarlet Engagement listed for Nintendo Switch, plus an unannounced 505 Games Switch 2 title

Bloodstained: The Scarlet Engagement has been listed for Nintendo Switch alongside an unannounced Switch 2 title from 505 Games. The Scarlet Engagement, a sequel to the original, was previously announced last year. Although there wasn’t any news about a Nintendo release, the latest discovery suggests that we’ll be getting it on Switch at the very least. It’d be somewhat surprising...

nintendoeverything.com logo
Mar 22 • 12:00 AM EDT • Technology • nintendoeverything.com
Families gather at Science Spectrum for Severe Weather Awareness Day

Families and community members gathered at the Science Spectrum on Saturday to learn how to stay one step ahead of weather emergencies.

kcbd.com logo
Mar 21 • 11:34 PM EDT • Science • kcbd.com
Today's NYT Connections: Sports Edition Hints, Answers for March 22 #545

Here's today's Connections: Sports Edition answer and hints for groups. These clues will help you solve The New York Times' popular puzzle game, Connections: Sports Edition, every day.

cnet.com logo
Mar 21 • 11:13 PM EDT • Sports • cnet.com
Japanese investment in Indian finance hits record as business ties tighten

Tokyo drawn to vast market where Chinese competition is limited by geopolitical tensions

ft.com logo
Mar 21 • 10:30 PM EDT • Business • ft.com
😐 Neutral (0%)
love
100%
Utica University Science Fair Inspires Young Scientists

Young scientists from local middle and high schools gathered for the 47th annual Utica University Regional Science Fair.

wktv.com logo
Mar 21 • 8:30 PM EDT • Science • wktv.com
Webb Telescope spots “impossible” atmosphere on ancient super Earth

Astronomers have uncovered surprising evidence of a thick atmosphere surrounding TOI-561 b, a scorching, fast-orbiting rocky planet once thought too extreme to hold onto any gas. Using NASA’s James Webb Space Telescope, researchers found the planet is far cooler than expected for a bare rock, hinting at a heat-distributing atmosphere above a churning magma ocean. This strange world—where a year lasts just over 10 hours and one side is locked in eternal daylight—may even be rich in volatile materials, behaving like a “wet lava ball.”

sciencedaily.com logo
Mar 21 • 8:00 PM EDT • Science • sciencedaily.com
Business investment in the era of digital transformation

The weak performance of business investment across the OECD since the Global Financial Crisis holds back potential growth. However, it masks a strong investment dynamic in digital assets such as hardware, software, and databases. This column describes how this divergence between digital and non-digital assets has intensified from the mid-2010s. The strong investment performance of the US relative to the rest of the OECD is almost exclusively a digital phenomenon. A ‘digital divide’ is emerging, where laggard countries are accumulating digital capital per worker more slowly than those with higher initial starting levels.

cepr.org logo
Mar 21 • 8:00 PM EDT • Business • cepr.org
Buffalo Museum of Science hosts DinoFEST this weekend

BUFFALO, N.Y. (WIVB) — The Buffalo Museum of Science got a little prehistoric Saturday. This weekend is DinoFEST where the museum educates visitors about paleontology, geology, and offers hands on …

wivb.com logo
Mar 21 • 6:59 PM EDT • Science • wivb.com
Milwaukee stair climb raises awareness for lung health and firefighters

The American Lung Association hosted its 18th annual stair climb in Milwaukee, where participants, including firefighters, climbed 30 stories to raise funds and awareness for lung health.

wisn.com logo
Mar 21 • 6:59 PM EDT • Health • wisn.com
"Derby of the dead child": This match changed football forever

When does a game become legendary? Is it when everyone can remember where they were at the time of the match? When the game has its own Wikipedia article? When the game marks a turning point in footba...

sports.yahoo.com logo
Mar 21 • 6:53 PM EDT • Sports • sports.yahoo.com
Iran launched missiles at US-UK military base in the Indian Ocean. Here’s what that says about its capabilities

Iran’s attempt to strike a US-UK base over 2,000 miles (over 3,000 kilometers) off its coast has renewed questions about Tehran’s military capabilities and how far its missiles can reach.

cnn.com logo
Mar 21 • 6:22 PM EDT • Politics • cnn.com
Deep dive
😐 Neutral (-2%)
ahah
39%
wow
33%
angry
28%
Saturday Sports: Sackets boys in the semis, plus lacrosse is underway

Here’s a recap of your North Country sports this Saturday.

wwnytv.com logo
Mar 21 • 6:21 PM EDT • Sports • wwnytv.com
Islanders @ Canadiens [Game #70 thread]

The Islanders have a big one tonight in Montreal, where the Canadiens are in a three-way tie for the Atlantic’s third playoff spots (84 points, same as wild card occupants Detroit and Boston but with a game in hand) while the Islanders begin a night of play on the outside looking in for the first […]

sports.yahoo.com logo
Mar 21 • 6:15 PM EDT • Sports • sports.yahoo.com
😐 Neutral (-1%)
wow
60%
ahah
40%