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Warriors' Moses Moody reportedly diagnosed with torn patellar tendon after being stretchered off vs. Mavs
Moses Moody went up for a breakaway dunk, but his left knee gave out in the final minute of overtime on Monday night.
Marathon has sold 1.2M copies across Steam, PS5, and Xbox
Alinea Analytics estimates show that Marathon has generated gross revenues of $55M via 1.2M copies sold on Steam, PS5, and Xbox: Looking at the split between Steam, PS5, and Xbox, Steam is clearly the main platform for Marathon, accounting for a little under 70% of the audience (800K copies sold). Meanwhile, PS5 takes about 19% (217K) and Xbox (including console, PC, and cloud) accounts for a bit over 11% or 133K. Marathon is technically a first-party Sony title, so seeing the home console struggle to break 20% of the volume is a notable data point for the ongoing platform-agnostic debate. PlayStation Studios online games will almost certainly continue being multiplatform (despite Sony reportedly pulling back on PC releases). Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe As for Marathon, the consensus among hardcore players who pushed through the awkward onboarding phase – myself included – is that it’s fantastic. The gunplay, aesthetic, and presentation are among the best in the shooter genre. A great game doesn’t always equal an immediate hit, though, as shown by our estimates. Things are looking lukewarm right now. But this might be one of those marathon-not-a-sprint situations. Had to, didn’t I? Why wasn’t Marathon a hit on the same level as Arc Raiders? One topic that came up in a lot of conversations at GDC this year was why Marathon hasn’t hit the same stratosphere as Arc Raiders. On paper, they’re both extraction shooters, and Marathon has the Bungie pedigree – the house that built the gold standard for gunplay in Halo and Destiny. Marathon’s neon-futuristic aesthetic also distinguishes itself from the gritty realism of Tarkov or the post-apocalyptic hope of ARC Raiders. But vibes can only get you so far for first impressions if the onboarding feels like a brick wall. Marathon is a sweaty PvP-focused experience with a first-time user experience and UI that I can only describe as dreadful. Players are dropped into a complex ecosystem where the UI, though visually striking, is functionally uninformative, forcing users to manually hover over nondescript, identical icons just to identify basic gear or weapon mods. This lack of clarity is compounded by punishing mechanics like a severe heat gauge for movement and a scarcity of vital resources, all without a clear tutorial or a low-stakes mode to learn the ropes. Most people – even top streamers and veteran shooter players – have no idea what’s going on in Marathon at first. Arc is on the complete other end of the spectrum. As we covered here and here, Arc Raiders offers a more collaborative, approachable loop where players often work together toward shared goals. And the objectives are instantly clear. To many players, this contrast only emphasised Marathon’s issues, especially during the testing period. Players understand the Arc Raiders loop within 30 minutes, while Marathon acts as a massive filter, chewing up newcomers and spitting them out before they can experience the depth of Bungie’s signature gunplay. What I’m getting at here is that the poor first-time user experience of Marathon’s Server Slam likely stifled launch sales, while the opposite was true for Arc. Let’s look at the pre-launch copies sold for each game during their respective Server Slams (launch-aligned) : Looking at the trajectory: Arc Raiders saw a massive 80% jump in copies sold during its three-day Server Slam (day -13 to -11). Players jumped in, realised the water was fine, and immediately opened their wallets. Marathon, meanwhile, saw a 49% increase in the four days following its Slam (Day -7 to -3). At the time of each game’s respective launch, Arc Raiders had nearly double the Steam footprint of Marathon – and word of mouth only continued to grow. Bungie could have had more time to fix the onboarding process had the beta happened earlier. But Marathon launched three days after the beta finished. These factors limited the launch sales quite a bit, I reckon. Marathon has found a niche audience, though Despite the friction-heavy start, the data suggests that those who survived Marathon’s onboarding are loving life. We’ve been tracking cross-platform DAUs, and while there’s the expected post-launch leakage, many players are sticking with it. After peaking at 478K total DAUs on its first Saturday, Marathon has settled into a respectable rhythm, holding 345K DAUs as of yesterday and averaging 380K DAUs across the weekend. Steam continues to do the heavy lifting here, consistently accounting for the lion’s share of the daily players. Players have been putting in the hours, too: On Steam, Marathon’s average playtime has climbed to 27.8 hours, significantly outpacing the console averages on PS5 (16.5h) and Xbox (17.3h). Even more telling than the averages: 22% of the Steam audience has surged past the 50-hour mark, and nearly 7% have already logged over 100 hours. Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe This data suggests that once the Bungie magic clicks, it hooks players deeper than the average extraction shooter. There’s also started to be a shift in the game’s discourse. Marathon launched as one of those games that’s cool to hate. But as Marathon’s 100-hour club grows, we’re seeing conversations around its mechanical merit outweigh the negativity. Several high-profile creators, who were initially vocal critics, have spent the last week coming around on the mechanical depth of the endgame. It’s a subtle but positive signal; the hate train is losing steam, and a new narrative about the game is emerging. Bungie faithfuls unite Another interesting metric in Marathon’s first few weeks is who, exactly, is playing. Bungie leans heavily on its prestige as the “makers of Halo and Destiny,” in its marketing, and that message has clearly hit the mark. On Steam, the gravity (hammer) of Bungie’s previous work is unavoidable. A staggering 78.2% of Marathon players also played Destiny 2. The trend carries across other platforms, with 74.2% of PS5 players and 82.7% of Xbox players also having played Destiny 2. The Halo legacy lives on, it seems. More on that in a bit. While Destiny 2 went free to play, these numbers still represent a high-intent migration of a fanbase that trusts Bungie’s specific brand of kinetic gunplay and cryptic world-building. The Xbox data adds another layer of legacy. About 85.7% of Marathon players on Xbox have played Halo Infinite, while over half of the Steam audience has spent time in Halo Infinite and 36.1% in the Master Chief Collection (a paid collection of the old Bungie-made legacy games). Interestingly, we see a 55.9% overlap with ARC Raiders on Steam. Overlap is even higher there on PlayStation (60.5%) and Xbox (66.5%). And there’s also significant crossover with Helldivers 2 on all platforms, too. Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe Bungie has found some of its fans with Marathon, and the challenge now is keeping this engaged in a high-stakes PvP environment when they’ve spent the last decade primarily enjoying the power fantasies of PvE. On that note… Go the full 26 miles? Or cut and run? Time for some could’ve, should’ve, would’ve. These things would have improved Marathon’s performance at launch: A more robust onboarding process, perhaps in the form of a short single-player/PvE campaign. We know Bungie fans love this stuff. A traditional arena-based mode akin to Destiny’s Crucible could have been a bridge for the cautious players who’d have been otherwise deterred by the Server Slam. It’s also a great palate cleanser after getting merked. Introducing a dedicated PvE environment would have similarly diversified the conversation and lowered the barrier for the Bungie faithful who found the pure PvP extraction loop too abrasive. PvE is safer than PvP these days. There’s an argument that a thin PvE mode would have just felt like a budget Destiny, potentially hurting the brand more. But given how dire the FTUE is, I think it would have been a net positive. Any kind of tutorialised loop that demystifies the stakes, really. While there is merit in a studio sticking firmly to a singular creative vision, and going all in on the hardcore extraction loop. Less forgiving is the technical reality is that the user interface and first-time user experience (FTUE) were not at a commercial standard for launch. Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe In a landscape where player time is oversaturated and the most contested currency, a flawed FTUE is a critical failure point. But it’s not all doom and gloom, as Marathon has an incredible, unique gameplay loop, suggesting that financial success is still attainable if Bungie can pivot effectively. Bungie and PlayStation now face a difficult strategic crossroads, though – one within a challenging games market. They could: Double down on Marathon with a long-term Rainbow Six Siege- or No Man’s Sky-style recovery plan, which is something I heard Last Stand Media’s Chris Maldonado mention last week. While this could be a sunk-cost fallacy in action, it could eventually yield the audience the game’s mechanical depth deserves. Shift focus toward the inevitable Destiny 3 or another project, mitigating the escalating opportunity cost and cutting their losses, so to speak. Doing both is an expensive proposition, given the high overhead and burn rate of operating out of Bellevue, Washington. With Sony recently demonstrating a lower threshold for underperforming studios and projects, the margin for error has vanished. Whatever happens, the next six months will determine whether Marathon becomes a cornerstone of Sony’s live-service portfolio or a cautionary tale of vision exceeding accessibility. I’m hoping it’s the former, because Marathon rocks. As always, hit subscribe to get updates on Marathon and other relevant games. Subscribe Want to get your hands on our data for yourself – for free? We’re offering a free trial of our platform for games companies. Send us a message here, or reply to this email, and we’ll set you up. The last word Reply to this email – or reach out here – if you have any feedback for the newsletter – or want to request a game for us to cover. [Alinea Analytics boasts the most accurate PC and console estimates in the business. Game makers use our platform to understand their audience, keep an eye on the competition, monitor sales trends, and spot new opportunities. We equip game studios and financial institutions with accurate data and the confidence to make smarter, data-driven decisions. Want to talk about all things games market data? We’d love to chat!]
My unsung hero of science: Buckminster Fuller, the architect who wanted to redesign the world (and inspired a nanosized one)
Few 20th-century scientific figures are as hard to classify as Buckminster Fuller.
Diagnosis for 3.23.26: Checking the pulse of Florida health care news and policy
Health care battles intensify as key bills advance
World Tuberculosis Day 2026: Primary health care key to a more accessible, people-centered response
In the Americas, an estimated 350,000 people fell ill with tuberculosis in 2024, and nearly 77,000 were not diagnosed, highlighting the need to bring diagnosis and treatment closer to communities.
Republicans at Risk of Losing Latino Support Ahead of Midterms
The economy, inflation and immigration are the top issues for Latinos ahead of the US midterms.
Denon expands its multi-room speaker lineup with the Home 200, Home 400 and Home 600
Denon takes on Sonos with three new speakers that are powered by HEOS wireless multi-room streaming.
Scientists found a rhino in the Arctic and it changes everything
Scientists have uncovered a new species of rhinoceros in the Canadian High Arctic, revealing that rhinos once lived far farther north than expected. The fossil, dating back 23 million years, is unusually complete and has helped reshape ideas about how these animals migrated between continents. Evidence suggests rhinos crossed from Europe to North America more recently than scientists once thought.
WHO recommends new diagnostic tools to help end TB
On World TB Day, the World Health Organization (WHO) is urging countries to accelerate action to end tuberculosis (TB) and expand access to lifesaving services by using new innovations such as diagnostic tests that can be used near the point-of-care and tongue swabs that can help detect the disease faster reaching more people.
Causal Inference Is Eating Machine Learning
Your ML model predicts perfectly but recommends wrong actions. Learn the 5-question diagnostic, method comparison matrix, and Python workflow to fix it with causal inference.
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
'Love Story' is Gen Z's analog dream life
The unplugged lives in "Love Story" feel remarkable to Gen Zers today. They're nostalgic for a time they don't even remember.
Amanda Peet Shares Breast Cancer Diagnosis
Amanda Peet detailed her recent breast cancer diagnosis in a new essay, sharing that her health battle coincided with both of her parents' final months in hospice care.
My postpartum mental health meant I spent five months on a mother and baby unit
Sofii Lewis was diagnosed with postpartum psychosis tendencies and OCD after giving birth.
How do I share a mental health diagnosis? | The therapist is in
Is there a way to share a mental health diagnosis but shield myself from hurt or judgment? How can I do it without changing a relationship?
Skin therapy business opening with celebration next month in the Poconos
The new location will offer customized skin rejuvenation treatments, including advanced exfoliation, LED light therapy, and modern facial technologies.
Skin therapy business opening with celebration next month in the Poconos
The new location will offer customized skin rejuvenation treatments, including advanced exfoliation, LED light therapy, and modern facial technologies.
Trump is eager to disclose details on others’ health – but not his own
President revealing congressman’s terminal diagnosis follows caginess about his own health, such as recent rash
With casino empire gone, Trump family bets on prediction markets
With his Atlantic City casinos in duress in the 1990s, Donald Trump saw a potential lifeline in sports betting and aggressively campaigned to legalize it in New Jersey. But when state powerbrokers shut him down, Trump vowed that he’d eventually find a way to win.
At age 41, a Westmoreland mom of 3 is diagnosed with a cancer that's rising in younger populations
When Misty Ament felt sharp pain in her right side last August, the 41-year-old assumed she was dealing with appendicitis. Instead, doctors discovered...
What Buffy's Nicholas Brendon Said About His Congenital Heart Defect, Cauda Equina Syndrome Before Death
Before Nicholas Brendon died on March 20 at the age of 54, the Buffy the Vampire Slayer alum and his sister had discussed his health diagnoses, including cauda equina syndrome and a heart defect.
'Keep it Kountry': How Kountry Wayne refused to code-switch and became comedy's most authentic voice
The Georgia-born comedian stands out through his authentic Southern voice and unconventional family dynamic as a father of 10, now breaking into film.
A baby dinosaur hidden inside rock reveals a first-of-its-kind discovery at UT Austin
A baby dinosaur fossil hidden inside solid rock for nearly 100 million years is now rewriting South Korea’s fossil record. Revealed using advanced CT scans at the University of Texas at Austin, the…
CEO transition puts pharma business in the driver’s seat at Aptar
The company that turned the condiment world upside-down is now turning drug delivery on its nose at the same time it elevates its pharmaceutical leader to CEO.
The nation’s cartoonists on the week in politics
Every week political cartoonists throughout the country and across the political spectrum apply their ink-stained skills to capture the foibles, memes, hypocrisies and other head-slapping events in the world of politics. The fruits of these labors are hundreds of cartoons that entertain and enrage readers of all political stripes. Here's an offering of the best of this week's crop, picked fresh off the Toonosphere. Edited by Matt Wuerker.
Which former Falcons are still available in NFL free agency?
Kirk Cousins, Leonard Floyd among former Falcons available in free agency
Hometown Health: Virginia teacher continues career through virtual academy after MS diagnosis
Suzy Mullins spent years not knowing what was happening to her body
Nextdoor Promotes Tony Castellanos to Executive Vice President, People as AI-Driven People Strategy Becomes Core to Business Growth
SAN FRANCISCO, March 19, 2026--Nextdoor Holdings, Inc. (NYSE: NXDR), the essential neighborhood network, today announced the promotion of Tony Castellanos to Executive Vice President, People. Castellanos will lead Nextdoor's People organization — including talent acquisition, compensation, HR business partnering, and benefits — as the company deepens its investment in AI-enabled People operations and continues to scale its workforce strategy.
Forum on harnessing Artificial Intelligence for health equity
Register to this forumOver the past decade, artificial intelligence (AI) has significantly evolved in complexity, performance, and utility. Its integration across a wide range of industrial sectors has accelerated, with healthcare emerging as one of the most transformative sectors. In this sector, AI has enabled high-impact applications – from enhancing the speed and accuracy of disease diagnosis and supporting clinical decision-making, to strengthening public health initiatives such as disease surveillance and workforce optimization. Moreover, AI holds immense potential to empower individuals, enabling them to take greater control of their personal health and well-being. Yet the central question remains: Who benefits, who is at risk, and do these innovations close or widen health inequities? While the potential of AI-enabled applications is substantial, many countries have approached their adoption with caution. This hesitancy stems from concerns about risks and benefits, including model bias, data breaches, privacy violations, and the erosion of professional skills due to over-reliance on AI. Additional barriers include inadequate data infrastructure and a lack of robust evidence on the most effective forms and interfaces of AI to enhance service delivery and system performance. Moreover, the rapid rise of Generative AI has introduced a heightened urgency for the development of comprehensive governance and ethical frameworks. The Asian Development Bank (ADB) Health Practice Team and Digital Sector, in collaboration with the World Health Organization (WHO) Regional Office for the Western Pacific, are convening the Forum on Harnessing AI for Health Equity on 25–26 March at ADB Headquarters. Senior health officials from 16 developing member countries (DMCs), alongside leading researchers, innovators, and policymakers from across Asia and the Pacific, will engage in discussions on how AI can be governed, financed, and scaled to deliver healthier lives for all. The forum is funded through the High-Level Technology Fund with support from the Government of Japan. Objectives The two-day forum aims to:Identify high-impact, evidence-based health AI use cases suitable for resource-constrained settings and map out a pipeline for potential supportIntroduce and validate the WHO's policy guidance on minimum necessary ecosystem for countries and institutions to self-assess readiness for AI adoptionObtain initial commitment from participating stakeholders to join a pilot regional initiative focused on data/model sharing for a priority health challengeEndorse a prioritized set of actionable policy recommendations focusing on governance, regulation, and sustainable financing necessary to scale high-impact health AI use cases in resource-constrained settings Target participants The forum will convene participants from 16 ADB DMCs including Bangladesh, Bhutan, Cambodia, Cook Islands, Fiji, Indonesia, Lao People's Democratic Republic, Mongolia, Nepal, Palau, Papua New Guinea, Philippines, Sri Lanka, Thailand, Uzbekistan, and Viet Nam. In addition, health system leaders and practitioners, private sector technologists, academic experts, representatives from civil society organizations, development partners, and philanthropic institutions engaged in AI for Health from Australia, the People’s Republic of China, Japan, Malaysia, New Zealand, Singapore, and the Republic of Korea will also be invited. SessionsDay 1 (25 March)Session 1: AI Use Cases for the Care Continuum: Improving Access and QualitySession 2: Adopting a risk-based approach for AI use case prioritizationSession 3: Establishing the Minimum Ecosystem for Implementation Risk ManagementSession 4: Future-Ready Health Workforce: Building Competency for Human-AI CollaborationDay 2 (26 March)Session 5: The Political Economy of AI in Health: Understanding Stakeholder Interests and their Impact on EquitySession 6: AI and Health Financing: Supporting Fair Coverage and ProtectionSession 7: AI Regulation and Oversight: Pathways for Different RealitiesSession 8: The Way Forward – Building Alliances and Regional Partnership How to registerThe forum will be held in a hybrid format. In-person attendance is by invitation only, while livestreaming of the forum will be available to the public. To register, please complete this form on or before 24 March 2026.Event organizers / partnersAsian Development Bank (ADB)WHO Regional Office for the Western Pacific High-Level Technology Fund (HLTF)ContactAkihito WatabeHealth Specialist, SD3-HSDawatabe@adb.org Jae Kyoun KimHealth Specialist, SD3-HSDjkkim@adb.org
Scientists recreated a dinosaur nest to solve a 70-million-year-old mystery
Scientists recreated a life-size oviraptor nest to understand how these dinosaurs hatched their eggs. Their experiments showed the parent likely couldn’t heat all the eggs directly, meaning sunlight played a key role. This uneven heating could cause eggs in the same nest to hatch at different times. The results suggest oviraptors used a hybrid incubation method unlike modern birds.
Kent meningitis outbreak has been contained, health officials believe
There is growing confidence that the 20 people diagnosed with the illness have not infected anyone outside the area
NCAA Tournament bracket 2026: The best team on each of the Nos. 1-16 seed lines in March Madness
Picking the best team on each of the 16 seed lines in the 2026 NCAA Tournament
Netflix’s #1 Documentary Is Wildly Controversial—and It Has People Terrified
Netflix’s latest #1 documentary is sparking major debate. Here’s why viewers are calling it eye-opening, unsettling and hard to ignore.
Paleontology has an Epstein problem. Women in the field say it's a symptom of a deeper misogyny
The names of hundreds of scientists have appeared in the Epstein files, including prominent dinosaur researchers. As the paleontology community reckons with the fallout of these revelations, women in the field say it's bringing to the forefront what they've known for years — that paleontology is ripe with abuse and harassment, and its institutions protect men at the top at the expense of women trying to build careers in spaces that treat them as disposable.
Scientists create a new state of matter at room temperature using light and nanostructures
Researchers at Rensselaer Polytechnic Institute (RPI) have created a new and unusual state of matter—known as a supersolid—by engineering how light and matter interact inside a nanoscale device. The ...
Machine learning analysis of CT scans
An AI-powered tool can interpret 3D images from CT scans and diagnose certain disorders.
Psychiatrists’ Use of Biomarkers Could Open a New Window Into Mental Health Diagnoses
The world’s largest professional psychiatry organization is preparing for the day when biological indicators can help diagnose and treat mental illness.
Cue Biopharma Reports Fourth Quarter and Full Year 2025 Financial Results and Business Highlights
Advanced research and development of CUE-401 for IND (Investigational New Drug) readiness –CUE-401 is the Company’s lead asset for the treatment of autoimmune and inflammatory diseasesAppointed industry veteran Lucinda Warren as Chief Financial and Business OfficerRaised net proceeds of $10.2M through an underwritten public offeringAnnounced strategic collaboration and license agreement with ImmunoScape to develop breakthrough cell therapy approach for solid tumors – Entitled to receive upfront
Trump reveals GOP congressman faced ‘terminal’ health condition and had months to live
President Donald Trump on Monday revealed that a GOP congressman had received a critical diagnosis and had only months to live before the president personally intervened to help him get emergency heart surgery.
Trump reveals GOP congressman faced ‘terminal’ health condition and had months to live
President Donald Trump on Monday revealed that a GOP congressman had received a critical diagnosis and had only months to live before the president personally intervened to help him get emergency heart surgery.
McKee nominates Beacon Bank president to chair R.I. Life Science Hub
If confirmed by Senate, William Tsonos would replace Neil Steinberg, who stepped down in July 2025.
Anbernic’s Next Handheld Might Flip the Script With a Rotating Screen
Anbernic may be preparing a rotating-screen handheld that mixes smartphone nostalgia with a bold new design and a fresh twist on Android gaming.
Trump Claims to Have Reversed a House Republican’s Terminal Diagnosis
The president leaned on House Speaker Mike Johnson to name a Florida Republican whose grave prognosis was imperiling the party’s already slim voting margin. Both said his prospects had improved.
Trump reveals story about GOP lawmaker Neal Dunn’s health
President Trump and Speaker Mike Johnson (R-La.) revealed Monday that Rep. Neal Dunn (R-Fla.) got a terminal diagnosis for a heart problem, prompting concerns about the House GOP’s super-slim major…
Trump reveals GOP congressman's terminal diagnosis
Trump said retiring GOP Rep. Neal Dunn, R-Florida, would have been \
President Trump, Speaker Johnson discuss Rep. Neal Dunn’s health during Monday press conference
President Trump told reporters Rep. Neal Dunn was seriously ill and said he had been given a grim prognosis, prompting urgent medical intervention.
Trump’s Chief of Staff Susie Wiles Is Working Through Cancer
Wiles, who is the first woman to serve as chief of staff, has been diagnosed with an early stage of breast cancer.
How plants moved from sea to land and changed Earth forever
A geoscientist explains how the first plants came to exist on Earth, long before the dinosaurs, and how their growth shaped life on our planet as we know it.
Susie Wiles, White House chief of staff, has breast cancer, Trump says
The president announced the White House chief of staff’s diagnosis Monday, saying she has a good prognosis and will continue to work while receiving treatment.
White House chief of staff Susie Wiles has early stage breast cancer, Trump announces
White House chief of staff Susie Wiles has been diagnosed with early stage breast cancer, President Donald Trump announced Monday.
White House chief of staff Susie Wiles has early stage breast cancer, Trump announces
White House chief of staff Susie Wiles has been diagnosed with early stage breast cancer, President Donald Trump announced Monday.
UK mortgage shelf-life nosedives amid market uncertainty; oil rising again
Rolling coverage of the latest economic and financial news
Giants' Hayden Birdsong to seek second opinion after troubling injury diagnosis
Giants righty Hayden Birdsong suffered a Grade 2 forearm strain and UCL sprain, a potential big blow for the young pitcher and San Francisco's staff.
Americans are now diagnosing their political opponents instead of understanding them
Psychological interpretation of political disagreement is replacing reasoned debate, leading to a culture of avoidance and echo chambers, and ultimately hindering democracy.
Ed Sheeran gives update on his wife's health following cancer operation
Ed Sheeran gave a health update on his wife, Cherry Seaborn, after her 2022 cancer diagnosis and operation: 'It was f---in' scary.'
Pilates Instructor, 72, Thought She Had the Flu. Then, a 'Shock' Diagnosis from Doctors Changed Everything
Pilates teacher Debi Weiss thought she had flu symptoms, but instead received a 'shock' diagnosis.
Aryna Sabalenka reaches Indian Wells final for 3rd time in 4 years
Aryna Sabalenka, a two-time runner-up at Indian Wells, will get another shot at winning after beating Linda Noskova 6-3, 6-4 in the semifinals.
Doja Cat reveals BPD diagnosis while defending Chappell Roan
'Need to Know' rapper Doja Cat shared that she wanted to be as honest as the 'Hot to Go!' singer Chappell Roan in a new TikTok.
NYC Health + Hospitals Receives Six Sing for Hope Pianos Designed by Artists - NYC Health + Hospitals
NYC Health + Hospitals’ Arts in Medicine department today announced the placement of six artist-designed Sing for Hope Pianos across the health care
PENN Entertainment Hotel Expansion Tests Value Of Brick And Mortar Investments
PENN Entertainment (NasdaqGS:PENN) plans a major expansion at Hollywood Casino Columbus with a new 203 room hotel tower. The upscale hotel is scheduled to open in June 2026 as part of a broader upgrade to the property. The project includes an expanded high limit table games room and is expected to create new local jobs. PENN Entertainment, which runs casinos, retail sportsbooks and online gaming platforms, is adding more hospitality capacity at one of its key Ohio properties. For investors...
The nation’s cartoonists on the week in politics
Every week political cartoonists throughout the country and across the political spectrum apply their ink-stained skills to capture the foibles, memes, hypocrisies and other head-slapping events in the world of politics. The fruits of these labors are hundreds of cartoons that entertain and enrage readers of all political stripes. Here's an offering of the best of this week's crop, picked fresh off the Toonosphere. Edited by Matt Wuerker.
75-Million-Year-Old Mystery: Scientists Uncover Tyrannosaurs’ Dark Secret
3D analysis of bite marks on a tyrannosaur foot bone shows that smaller tyrannosaurs scavenged carcasses, likely consuming the final remains after most flesh was gone.
Course-based research experiences opens science opportunities
When Maribel Lupe took biology at her rural Fresno County high school, she didn’t get opportunities to do lab work. As a Fresno State undergraduate, she was able to work hands-on in scientific research through the Course-based Undergraduate Research Experiences (CUREs) program. The opportunity to do research work transformed Lupe from a disengaged student to […]
A large fossil leg bone hints at T. rex’s origins, but scientists disagree
A new analysis of a large fossil shinbone suggests T. rex ancestors came from North America instead of Asia. Not everyone agrees.
‘Unusually large’ tyrannosaur leg bone points to 10,000-pound behemoth
It’s nipping at Sue's heels.
A major change could be coming in mental health diagnoses, psychiatrists say
The world’s largest professional psychiatry organization is preparing for the day when biological indicators help diagnose and treat mental illness.
An odd-nosed crocodile ate our prehistoric ancestors
‘Lucy’ probably needed to watch her back.
Depression may start with an energy problem in brain cells
Researchers have discovered a surprising change in how cells produce energy in people with depression. Brain and blood cells in young adults with major depressive disorder produced more energy molecules at rest but had trouble increasing energy production when needed. Scientists believe this imbalance may contribute to symptoms such as fatigue and low motivation. The finding could help pave the way for earlier diagnosis and more personalized treatments.
CVS Health’s Aetna to Pay $117.7 Million to Resolve False Claims Act Allegations
Aetna was accused of submitting false patient diagnosis data for its Medicare Advantage Plan enrollees in order to get higher monthly payments from the Centers for Medicare and Medicaid Services.
With its fluorescent characters and ASCII text, Marathon is a masterclass in 90s nostalgia
The revival of this 90s favourite is a retro-futuristic fever dream that is first incomprehensible, then thrillingly evocative. Plus, Donald Glover’s Yoshi debut
This billionaire wants to make science better, especially for AI
In this edition of AI Prognosis: Seemay Chou and Becky Pferdehirt's bold vision for how Radial will change science for AI
Healthcare Uses Specialized Language. It Needs Specialized AI, Too.
The potential generative AI in healthcare is enormous. They can generate patient education materials or clinical notes in seconds, flag incomplete documentation to keep care on track, or even suggest differential diagnoses . But when generalist models encounter the specialized “dialects” used across medical fields, they can miss critical clinical meaning—even when they read every word correctly. The result can be flawed decisions and eroding clinician trust. Healthcare organizations should treat AI like a supervised trainee: adapt models to clinical specialties, require transparent reasoning, and calibrate automation with human oversight.
How to Solve One of the Most Expensive Problems in Employer Healthcare
A small share of employees drives a disproportionate share of employer health-care spending: They are patients whose complex conditions go undiagnosed as they cycle through a fragmented care system. A diagnostic-focused “center of excellence” model—such as the Mayo Clinic Complex Care Program—offers a different approach: coordinated, multidisciplinary evaluations that identify the right diagnosis quickly. Evidence from employer claims shows that earlier, accurate diagnoses can improve outcomes, reduce unnecessary procedures, and lower costs by shifting care from repeated testing toward targeted treatment.
Democrats ask what happened to millions earmarked for Trump’s library
ABC, Meta, Paramount and X reportedly agreed to pay at least $63 million in settlements with the president. The original fund was dissolved last year.
Mobile brain scans sound like science fiction. But they're now helping more Canadian patients
A rising number of Canadian facilities are using mobile brain scanners to help patients, by offering MRIs mid-surgery in hospital or diagnosing stroke right on the roadside. So what's the future of this game-changing technology?
visionOS 26.4 unlocks support for 'world’s most advanced flight simulator' on Apple Vision Pro
When Apple releases visionOS 26.4, Apple Vision Pro will be able to display the “world’s most advanced flight simulator” for...
Hours After Announcing Donald Glover as Yoshi in the Super Mario Galaxy Movie, Nintendo Has Now Revealed Its New Yoshi Game Release Date
It's been a busy 24 hours for Yoshi fans. Following confirmation that Donald Glover will voice the elastic-tongued dinosaur in The Super Mario Galaxy Movie, we now know the release date for Yoshi's next game.
Sonos announces two new products, including $299 portable AirPlay 2 speaker
Remember that leaked Sonos speaker from just over a week ago? It’s now official, and there’s a second new Sonos...
Sonos is releasing its first consumer speakers since 2024
Sonos is moving on from the app debacle.
The Sonos Play puts the best parts of the Era 100 in a portable speaker
The Sonos Play portable speaker and Era 100 SL are the company's first new products since 2024.
Introducing Hims & Hers Benefits, Unlocking Health & Wellness Discounts for Subscribers
The program debuts with Prenuvo and Eight Sleep, providing discounts on advanced diagnostics and sleep technology Hims Hers Health, Inc. (NYSE: HIMS), the leading health and wellness platform, today announced Hims Hers Benefits, a new way for subscribers to access the best innovations in whole body health. This new initiative provides active subscribers access to discounts from health partners, all in one place, including whole body MRI scans from Prenuvo and adaptive bed systems from Eight Sleep. This is just the beginning of a larger benefits program that will make comprehensive, holistic care more accessible and affordable for subscribers. “True health doesn’t happen in a vacuum. It’s the result of the data you gather, the insights you can access, and the daily choices you make,” said Dheerja Kaur, Chief Product Officer at Hims Hers. “By leveraging our scale, we’re bringing health and wellness innovations like Prenuvo’s whole body MRI scans and Eight Sleep’s
This Giant Dinosaur Walked in Circles 150 Million Years Ago – Scientists Uncover Its Secrets
A rare looping dinosaur trackway in Colorado reveals new clues about sauropod movement and hints that the massive animal may have walked with a limp.
A Simple Photo of Your Hand Could Detect a Rare Health Disorder
The future is in your fist.
A Simple Photo of Your Hand Could Detect a Rare Health Disorder
The future is in your fist.
This 2-pound dinosaur is rewriting what scientists know about evolution
A nearly complete dinosaur skeleton discovered in Patagonia is helping scientists crack the mystery of alvarezsaurs, a bizarre group of bird-like dinosaurs. The fossil of Alnashetri cerropoliciensis reveals that these animals became tiny before developing their later specialized features, such as stubby arms and ant-eating adaptations. Weighing under two pounds, the dinosaur is one of the smallest known from South America.
'It's a very unique biological specimen': The scientists using menstrual blood to diagnose diseases
From diagnosing endometriosis and cervical cancer to diabetes, vitamin D deficiency, and pollution exposure, here's what menstrual blood can reveal about your health.
What crocodile bones teach us about dinosaurs
Paleontologists have often determined how old a dinosaur was by counting the growth rings in its bones. Just like with trees, it was thought that each ring corresponded to a single year of age. But researchers who studied crocodiles at an outdoor recreation center near Cape Town appear to have poked a hole in that approach. In the crocodiles, which are some of the closest living relatives of dinosaurs, there was more than one growth ring laid down per year. The results contribute to a growing debate over the best way to age animals.Read more of freelance science reporter Ari Daniel’s story here.Interested in more on the future of science? Email us your question at shortwave@npr.org.Listen to every episode of Short Wave sponsor-free and support our work at NPR by signing up for Short Wave+ at plus.npr.org/shortwave.
How ADHD diagnosis helped my mental health
Letter: I spent my life pre-diagnosis suffering from depression and low self-esteem, writes Francesca Finch-Andrews
This is why you only breathe out of one nostril at a time
One of the most bothersome things about being sick or having seasonal allergies is that it makes your nose stuffy and blocked. This makes breathing in through your nostrils frustrating – if not altogether impossible.
Bengals Legend Willie Anderson Shares Major Health Update After Kidney Transplant
For a man who spent his career protecting his quarterback, Cincinnati Bengals legend Willie Anderson just won the most important battle of his own life. After being diagnosed with kidney disease about a decade ago, Anderson recently underwent surgery.
'It was a deal': Bellingham native buys Pacific Science Center's stegosaurus head for thousands
A Bellingham native invests in the Pacific Science Center's stegosaurus head as the dinosaur exhibit faces closure and disrepair.
MINNEAPOLIMEDIA ENTERTAINMENT This Weekend in the Twin Cities Entertainment Guide | March 7 to March 8, 2026
Broadway, live music, Gophers hoops, dinosaurs, taiko drums and maple syrup. The Twin Cities is packed this weekend. Get out there, March 7 to 8. Winter is not done with us yet.
MINNEAPOLIMEDIA ENTERTAINMENT | This Weekend in the Twin Cities: Entertainment Guide - March 7 to March 8, 2026
Broadway, live music, Gophers hoops, dinosaurs, taiko drums and maple syrup. The Twin Cities is packed this weekend. Get out there, March 7 to 8. Winter is not done with us yet.
Star NASCAR driver to miss race after health diagnosis
Alex Bowman was diagnosed with vertigo and will miss this weekend's race at Phoenix Raceway.
The nation’s cartoonists on the week in politics
Every week political cartoonists throughout the country and across the political spectrum apply their ink-stained skills to capture the foibles, memes, hypocrisies and other head-slapping events in the world of politics. The fruits of these labors are hundreds of cartoons that entertain and enrage readers of all political stripes. Here's an offering of the best of this week's crop, picked fresh off the Toonosphere. Edited by Matt Wuerker.
Selena Gomez was 'misdiagnosed' before getting the correct mental health assessment
Selena Gomez has been open about her bipolar diagnosis, but it was a long road to understanding what was truly going on with her mental health.
Opening date set for Cosm entertainment venue at Centennial Yards
A giant immersive entertainment venue being built across the street from Mercedes-Benz Stadium just got an opening date.
Opening date set for Cosm entertainment venue at Centennial Yards
A giant immersive entertainment venue being built across the street from Mercedes-Benz Stadium just got an opening date.