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A Newer Approach to Editing Embryos Ignites Debate
Fertility specialists, biotech companies and ethicists are divided over whether progress in early gene editing would wipe out diseases or trigger a rush toward enhancement.
Scientists discover a hidden cause of aging cells that can be reversed
Researchers discovered that declining levels of phosphatidylcholine may be a major cause of age-related mitochondrial dysfunction and loss of cellular energy. Remarkably, boosting this nutrient restored more youthful mitochondrial performance in aging organisms, suggesting some aspects of aging can be slowed or reversed.
Browns QB Deshaun Watson says this is the first time he's been fully healthy since 2023 Week 3 vs. Titans
The largest scorpion to walk the Earth was the size of a baseball bat
Scientists describe a baseball bat-size scorpion — the world’s largest — and suggest that the 400 million-year-old creature was also amphibious.
In a first, scientists translated an entire viral genome so a quantum computer could read and analyze it
Scientists have uploaded a viral genome to a quantum computer, marking an important step for the future of quantum-enabled advancements in biology.
How science is securing Michigan's pork future
Seventy-five percent of state's pigs are now covered by an SPS on-farm biosecurity plan, strengthening the responses farmers will have to an FAD.
Archetype Entertainment founder and BioWare veteran wishes Exodus didn't look so much like Mass Effect
But he thinks the team is doing a "good job" moving it further away from BioWare's sci-fi romp.
Biochemistry Student to Participate in National Science Foundation Undergraduate Research Program
Elmhurst University biochemistry major Hannah Cardenas ’27, of Des Plaines, Illinois, received a National Science Foundation Research Experiences for Undergraduates (NSF REU) award to participate in a 10-week summer research internship at the University of Texas at Dallas.
Biobehavioral health researcher earns Lloyd Prize for Innovative Health Research
Penn State’s Social Science Research Institute has announced Mohanraj Krishnan as the recipient of the 2026 Lloyd Prize for Innovative Health Research made possible by an endowment created by Penn State Professor Emeritus Thomas Lloyd, who served on the College of Medicine faculty for 46 years.
Texas A&M advocates nutrition education for tomorrow’s nurses
The Nutrition-to-Nursing pathway provides a deeper understanding of the biological systems that underpin health and disease.
The Franklin Institute and GSK celebrate 40 years of GSK Science in the Summer™ with a new "Be a Chemist!" theme and program expansion
A free hands-on STEM enrichment program led by The Franklin Institute and supported by GSK, celebrates its 40th anniversary in 2026.
Earth's first animals barely evolved until sex changed everything
Earth’s earliest animals may have held evolution back because they reproduced asexually, creating low-competition communities that changed very little over time. When environmental pressures pushed them toward sexual reproduction, biodiversity exploded and evolution accelerated dramatically.
Popular joint supplement glucosamine linked to faster Alzheimer’s progression
A major study suggests glucosamine, a popular supplement for joint pain, could be linked to faster progression from mild cognitive impairment to Alzheimer’s disease. Researchers found a 25% higher likelihood of developing dementia among glucosamine users and uncovered biological clues that may explain why.
How sky-high ticket prices, war & politics could impact the World Cup
The biggest World Cup ever starts this week. Laura Williamson, editor in chief of The Athletic, describes how sky-high prices, travel restrictions, politics and the Ebola outbreak are impacting fans. Williamson also discusses President Trump’s UFC event on the White House lawn. Ken Tucker reviews Kacey Musgraves’ album ‘Middle of Nowhere,’ which he says pairs well with the music biography ‘Gary Stewart: I Am From the Honky-Tonks.’
President’s message: Progress and opportunity for science and medicine
his is an extraordinary moment in time for the biomedical sciences. Seven decades ago, the discovery of the structure of DNA sparked a revolution in understanding life. In the decades since, the knowledge of fundamental biology we have accumulated has led to innovative treatments for many difficult-to-treat diseases, and many more are now within reach....
Sex jumpstarted Earth’s animal biodiversity
Many species didn’t have much sex for millions of years. They didn’t need it.
Hubble Science in the 2030s White Paper: High-Contrast Optical and UV Spectroscopy with HST/STIS
The Space Telescope Imaging Spectrograph (STIS) on the Hubble Space Telescope currently stands as the sole space-based astronomical facility providing visible-light coronagraphic imaging — and the only facility anywhere that can perform both visible- and ultraviolet-light coronagraphic spectroscopy. In imaging, STIS offers unparalleled stability that rivals the performance of ground-based direct imaging in the optical, […]
The Code As Witness: A Book About Science, Politics & Pandemic Inquiry
The Code as Witness written by Steven C. Quay is part scientific investigation, part policy strategy, and part warning about the future of biological research.
The Code As Witness: A Book About Science, Politics & Pandemic Inquiry
The Code as Witness written by Steven C. Quay is part scientific investigation, part policy strategy, and part warning about the future of biological research.
Scientists Unethically Experiment On the Unborn to Improve Gene Editing Techniques, Bioethicist Says
Genetic researchers are experimenting on unborn children in trials that could have been done on animal embryos, according to one bioethicist.
23 student researchers receive 2026 NSF fellowships - College of Arts and Sciences
The National Science Foundation awarded work in STEM-related fields such as artificial intelligence, biomedical engineering and marine ecology.
GREX-PLUS Science Book v2
GREX-PLUS (Galaxy Reionization EXplorer and PLanetary Universe Spectrometer) is a mission candidate for a JAXA strategic L-class mission to be launched in the 2030s
Your DNA is changing all the time. Here’s why
We tend to think of the DNA strands that contain our genetic code as consistent, stable units. But in reality, the cells that make up our bodies are constantly replicating and changing. Even as you read this sentence, in fact, the genes within your cells are mutating. So, what causes these mutations and what’s the impact? Science writer Roxanne Khamsi examines the answers in her new book, Beyond Inheritance. Today on the show, she gets into how scientists examine these mutations, how they’ve shifted our understanding of disease and what the future of genetic therapy could entail.Interested in more biological and life sciences? Email us your question at shortwave@npr.org.Listen to every episode of Short Wave sponsor-free and support our work at NPR by signing up for Short Wave+ at plus.npr.org/shortwave.
BEACON: How Benchmarking Combats the Reproducibility Crisis in Modern Science
A new initiative called BEACON aims to advance scientific reproducibility by uniting siloed benchmarking efforts across biomedical research.
NASA Spaceline Current Awareness List #1,203 5 June 2026 (Space Life Science Research Results)
NASA Spaceline Current Awareness List
Planetary Science Analysis and Assessment Group Support
Earlier this year it was announced that NASA’s Planetary Science Division to cease financial support for planetary science Analysis/Assessment Groups (AGs), effective the end of April 2026.
Lyme Primer: How the New HHS Strategy Stacks Up To Science
Experts support targeting ticks but caution against the long-term use of antibiotics.
We can create the future of science right now
Paul Litvak is the founder and Executive Director of the Robyn Dawes Institute and a Visiting Scholar at UC Berkeley. He has a PhD in Behavioral Decision Research from Carnegie Mellon where he studied emotions and the sunk cost bias. Over 15 years in industry, he solved a wide range of challenging technical problems. At Meta he created models optimizing the ad review process. At Google he ran experiments to measure social influence. At Airbnb, he was a product manager leading machine learning teams optimizing search ranking and price suggestions. He also co-founded and led product at Rhythmic Health, a venture-backed biosensing startup, creating an accurate low cost system using a color changing strip and a smart phone to measure salivary lactate. The bottleneck At this point, it is uncontroversial to say that science needs to stop using the PDF article as the unit of knowledge and currency. The unbearable slowness of scientific publishing, the profit motive and margins: I’m not saying anything new. The PDF also sucks because it’s hard to extract structured information, which makes it hard to do evidence synthesis. As a result, we do much less evidence synthesis than is needed. And evidence synthesis ultimately undergirds most policy and medical decision-making. I can see second-by-second real-time odds for any sporting or newsworthy event, but a school board can’t see the best evidence on whether their 8th graders should be taught algebra. As a society, we don’t treat this as an important problem. Again, not controversial. Not only is the problem well understood, but the solution has already been laid out. What we need is AI-assisted living evidence synthesis - (1) an open knowledge graph of atomic claims, (2) claims linked to evidence, (3) assessment and synthesis of each piece of evidence, and (4) continuous updating with new data. What few realize (yet) is that the technical capacity to build this vision for a significant portion of science already exists. Not only that, scientists and startup teams are already building many of these components. I know this because I’ve been surveying the space and talking to many of the builders. There are some missing pieces: for example, evaluations of how well some of the components work. But at this point, most of what’s missing is a fully end-to-end working integration of all of these parts. In the rest of this essay, I’m going to lay out all the parts of a working living evidence layer for science and who is working on them, and propose concrete next steps for building this system. What’s now possible The diagram above outlines the components of a living evidence synthesis platform, including some of the teams working on each component1. Scientific PDFs are processed into claims with associated evidence. The evidence is subjected to a forensic audit, methodological evaluation and robustness and reproducibility checks. Finally it’s given a weight in a continuously updating synthesis. What follows is a description and status of each component and a few of the teams working on them. Document understanding The first thing you need to be able to do is turn an article into structured data. Mostly that means parsing PDFs. There are often multicolumn layouts that confuse non-specialized PDF to text processing libraries. For scientific papers, there is the added complexity of parsing formulas and tables and figures. This is a really hot area - there are startups offering APIs, and it seems like a new open source package gets posted to Github every few weeks. What follows isn’t exhaustive. A package called GROBID was the state of the art for a while, they didn’t update their package for nearly two years until very recently. In the meantime reducto.ai released an AI powered PDF extraction API, PaddleOCR became popular, IBM released a model called Docling, and both Mistral and Gemini created models and libraries. I also know of at least one other well-funded psychology research group working on a paper parser. By contrast, there are few open evals in this space, with no extensive evals for complex table comprehension in particular. Nonetheless, I’m confident this will be a solved problem soon, given the combination of LLM advances and developer interest. Hypothesis level extraction There has been increasing interest in comprehending the extracted text of papers and linking information to evidence for each hypothesis. A lot of work has already been done. Trialstreamer (Marshall et al. 2020) and RobotReviewer LIVE (Marshall et al. 2023) demonstrated automated extraction of trial population, intervention, and outcome at scale on clinical RCTs. PaperQA2 (Skarlinski et al. 2024) and Ai2 ScholarQA (2024) extended this to retrieval-augmented question answering with citation grounding. Elicit, Consensus, and SciSpace operationalized claim-level extraction for end users. OpenEval (Booeshaghi et al. 2026) is the most recent and most ambitious: 1.96 million atomic claims extracted from 16,087 eLife manuscripts using Claude Sonnet 4.5, grouped into ~299,000 results, with LLM evaluations showing 81% agreement with human peer review on a 2,487-paper subset. None of these solutions link claims to test-statistics, as you would need to evaluate randomized controlled trials. This is why I built the evidence.guide API - to extract hypotheses and associated test statistics from behavioral science papers. The best public eval of this kind of extraction I’m aware of comes from the recent SCORE project - they had humans code thousands of psychology papers to extract their claims by hand. It would be extremely helpful to the world if all scientific PDFs were available as structured open data. I’ve been working to make this happen, both directly at Berkeley and through coordination with large entities I can’t yet speak of; as hard as it is to do, I think it’s possible2. Forensic audit A lot of work has been done on forensic audit, but some gaps remain. Of course, for biology papers that rely on images for evidence, there are a variety of tools (notably Proofig and ImageTwin) to spot anomalies. These are still well short of what sleuths like Elizabeth Bik can do on her own, but these tools are constant companions among fraud analysts. There’s someone working on auditing Excel files for anomalies, and a number of teams are automating numerical checks like GRIM and SPRITE, including Scrutiny project, the INSPECT-SR team as well as statcheck. The regcheck team is building a way to use AI to compare preregistrations to analyses in papers, to ensure there aren’t significant deviations. Nonetheless, there are many other kinds of anomalies to screen for, both public and less publicly known. And there are no formal evals for anomaly detection that I’m aware of. Still, there’s a lot to draw from in this space and I’m pretty certain we will be able to scan papers for most kinds of obvious anomalies in the near future. Methodological review This area has been white hot, though I fear for many of the startups in this space, because this capability may become commoditized. There are at least six different AI peer review companies, including Refine.ink, Reviewer3, ReviewerZero.ai, Q.E.D. Science, Paper Wizard, and Isitcredible. Coarse (a pun on refine) was also recently created as an open source alternative. These systems provide qualitative feedback on the content of papers, spotting methodological weaknesses and mathematical errors. They seem to work pretty well, and many academics report bitterly that they exceed the average quality of typical peer reviewers. But there are few evals here either. What evals exist so far involve using LLM-as-judge (circularity problems abound) or comparing against human reviews of questionable quality. What you’d ideally want is an eval that measures capturing known errors in papers3. Reproducibility and robustness Another active area has been using AI agents to automate computational reproducibility4 and robustness5 checks in papers that report numerical results. For more recent papers where data and code are available, AI agents can see whether they can re-run the analyses and produce the numbers reported in the published paper. In addition to a handful of individual academics who have been experimenting using Claude Code for this, the Institute for Replication is a leading group working on building an end to end system. The evals related to this problem are the most mature, with CORE-Bench (Siegel, Kapoor, Narayanan 2024) and PaperBench (OpenAI 2025) available to benchmark agents on this task. There is also work on getting AI agents to test alternative ways of analyzing the data to ensure the results are robust to small analytic design choices. Synthesis This is the most underdeveloped area where significant investment is required. Although some automated evidence synthesis systems exist — for example, otto-sr is building an AI agent to write systematic reviews — none of these incorporate the full range of paper level signals to weight evidence appropriately. Nor is there anything like an eval or a gold standard for a good systematic review. Arguably Cochrane reviews are the closest we have to gold standard human systematic reviews, though I’ve heard academics in the know complain about their uneven quality. A key question for a synthesis platform is how to weight anomalies and methodological issues in assessing the quality of a piece of evidence. This is an unsolved problem and one I’m very keen to work on. Continuous updating There are many pieces of basic infrastructure available for monitoring for new research and initiating updates. OpenAlex is the current open citation graph. Retraction Watch integrated into Crossref in October 2023. Scite tracks how citations support, contrast, or mention prior claims. The Living Evidence Network demonstrated continuous-update workflows in clinical guidelines. Engineering this is a relatively straightforward task. When you look over this technical architecture and all the progress being made, it’s hard not to be optimistic that a living guide to scientific evidence will be built. The stakeholders are ready The social infrastructure for this is starting to coalesce — it’s not just a pie in the sky academic exercise to imagine this coming into existence. Institutions like the Center for Open Science, the Institute for Replication, the INSPECT-SR, the Living Evidence Network and more are all working on scaling work to improve research quality. Funders are also aligned. The Sloan Foundation has funded living evidence work through COS. Coefficient Giving supports the Institute for Replication and COS. The Astera Institute and the Institute for Progress have shown interest in this space. NIH has established an Office for Replication and Reproducibility. Although there are (very unfortunately) serious headwinds in science funding generally, there is an active group of funders interested in metascience. A brief word about what I’ve been doing at RDI. First, as a Visiting Scholar at Berkeley I’ve been actively figuring out how a non-profit and a public university can conduct and make public the results of large-scale academic article data mining. With some of the money I raised from donors, I commissioned a legal analysis of recent case law and publisher text data mining (TDM) agreements in order to understand whether a massive open data mining of academic articles is possible (with caveats, it is). I’ve also been working to bring together stakeholders in this space, and identify gaps. I’ve also been doing some software development in this space, with more to come. A pilot proposal The assumption undergirding all of this is that an AI, given all this information, would make the right judgment about a scientific claim with lots of conflicting evidence, weighing all the factors appropriately. That’s the hypothesis we need to test. Randomized control trial research is the best place to focus on first. RCTs are used to make many of the important decisions in society - from medical trials to public policy changes. And they use a relatively uniform set of inferential statistics with lots of known and available diagnostics. Behavioral science experiments, within the broader realm of RCTs, should be first used as a testbed whose results can be generalized. Because behavioral science is at the vanguard of open science practices, replications abound (there are thousands of them) to serve as ground truth training data. Key Hypothesis Therefore the pilot would test, in behavioral RCTs that have been replicated, whether the quality of evidence for a claim can be used to accurately predict whether that claim will replicate. Secondary Hypotheses Compared to claims that replicated, non-replicated claims demonstrate a greater share of forensic anomalies in their source literatures. Hypothesis level claim and statistic extraction is accurate enough to scale living evidence without onerous human review costs. Replication prediction is more accurate than prediction markets6 or journal prestige. If all the different quality signals we gather do accurately predict which studies will replicate, then we can use that model to score evidence to power the living evidence layer. Why this is informative regardless of outcome If the pilot succeeds, the architecture extends to medical RCTs (where Living Evidence already operates and integration is mostly about claim representation), then to slices of basic biology with stable replication structure. If it fails, the field learns which quality signals are load-bearing and which ones metascience has oversold. Either result is a contribution to knowing what the literature supports. Implications for funders Because this burgeoning ecosystem of builders already exists, a well-informed philanthropic or government funder could play a crucial catalyzing role in bringing this future about. They could play at least three roles: creating open structured datasets, publishing open benchmarks and incentivizing the solving of key technical challenges. First, open archives of papers that the government maintains, like PubMed, could be turned into structured data amenable to large scale metascience and claim aggregation. I know the US government already has an interest in doing this, though some key open questions remain unanswered. How do you determine the best models and systems for accurately extracting information from papers? How can you establish a robust way to allow researchers to flag errors and correct them? And finally, how do you create a legal regime in working with publishers to maximize the scope of available papers? For the latter, a university or a private philanthropy may be better positioned to make structured data publicly available under journal subscription terms or fair use. Philanthropists or government funders could also coordinate to create or commission benchmarks that evaluate whether important problems have been solved. For example, an open benchmark for claim extraction from a range of different scientific article types would be extremely helpful. Ensuring the underlying data are accurate is vital for creating these evaluations. I’ve discussed opportunistically using various human-created datasets for this purpose, but a consistent problem is that errors in human data make it difficult for them to serve as a gold standard. Finally, with structured data and benchmarks available, the government or private philanthropy could use them to incentivize groups to develop machine learning systems that meet these benchmarks. Prizes are one potentially valuable tool for this. For example, you could establish a prize for a system that accurately updates a living meta-analysis for a small set of claims. Prizes are particularly useful as signals of problem importance, and can help create vibrant ecosystems of public and private research—see, for example the role the government played in kickstarting the current work on nuclear fusion. Conclusion The drawbacks of the current scientific publishing system are known. Scientists agree, metascientists agree, philanthropists agree: the published PDF plus citation graph isn’t the right substrate for maintaining a representation of the evidence base in science. The pieces needed to build the alternative either already exist or are rapidly taking shape. The community is forming around exactly this problem, with concrete partnerships and shared infrastructure. A pilot should start on behavioral science RCTs because that’s the slice of empirical science most amenable to legibility, where replication ground truth is richest, and where the failure modes are best documented. What’s been missing is the galvanizing mission to assemble these pieces into something that works. That’s what I’m proposing to build. *** 1 I have a broader field map that I’ll release publicly soon. This is me, building in public! 2 If this is something that you are excited about, please reach out and talk to me. 3 More on this very soon too! 4 This tests whether, given the code and the data, you can get the same statistics as reported in the published paper. 5 This tests whether the results are the same as a paper’s given alternative analytical decisions in conducting the analysis (like outlier omission). Closely related is the idea of a “multiverse” where you come up with many different ways of answering the same underlying research question with the same data, and test whether the results hold in all those alternative methods. There’s been work on the latter as well. 6 Some of the replications, e.g. those from the SCORE project, had paired the experiments with forecasts from prediction markets. So we get to look at this for free.
World Pork Expo discussions driven by swine disease and herd health
Swine disease pressure and herd health were major topics during last week’s World Pork Expo in Des Moines. CBS Bio Platforms vice president of innovation and commercialization Rob Patterson says the threats aren’t universal. “Every producer has their own challenge, their own way of doing business.” He tells Brownfield their technology and innovative approach is […]
Materials lab in national program to develop wearable eye health system
The Advanced Research Projects Agency for Health, an agency within the U.S. Department of Health and Human Services, has awarded up to $75.8 million to four research teams through its Ocular Laboratory for Analysis of Biomarkers program. Researchers from Penn State will develop biosensors for the Closed-Loop Sensing and Microdosing for Dry Eye and Systemic Disease Management (COSMIC) team led by Lacristat, a California-based ophthalmology company.
Grants fund high-risk research on fungal disease and antibiotic resistance
Schwartz Research Fund Visionary Grants for faculty members in the life sciences aims to provide significant assistance for innovative, visionary research that opens an important new line of inquiry.
If stress is wreaking havoc on your gut, late-night snacking may make it worse
Eating late at night may compound the harmful impacts of stress on your digestive health and gut microbiome, according to recent research.
Paving the way for agents in biology
Anthropic is an AI safety and research company that's working to build reliable, interpretable, and steerable AI systems.
The Rockefeller University » Interactive Kitchen Lab will showcase the art and science of cooking
Led by a professional chef, the event highlights the chemistry, biology, and neuroscience of food through tastings and sensory experiments.
California wants to cap business tax credits, alarming life sciences and tech industries
California's life sciences industry, and some lawmakers, urge state leaders to reject budget proposal to permanently limit R&D tax credits.
ProBiotix Health targets long-term women’s health beyond menopause symptom support
Women’s health research is growing, and scientists are learning that supporting consumers through menopause means going beyond addressing symptoms. Cellan Davies, head of marketing at ProBiotix Health, tells Nutrition Insight which menopause-support ingredients and formulation approaches are gaining the most traction within women’s health.
Scientists achieve the first total synthesis of a complex alkaloids isolated from plant
Monoterpenoid indole alkaloids (MIAs) are plant-derived molecules with unique pharmaceutical potential, but their highly complex and intricate structures make them difficult to produce in the laboratory. Now, researchers from Japan have developed a new strategy that enables the total synthesis of bisleuconothine A and bousigonine B, two biologically relevant oligomeric MIAs. Their findings lay the foundation for further studies of this family of molecules. Monoterpenoid indole alkaloids (MIAs) are plant-derived molecules with unique pharmaceutical potential, but their highly complex and intricate structures make them difficult to produce in the laboratory. Now, researchers from Japan have developed a new strategy that enables the total synthesis of bisleuconothine A and bousigonine B, two biologically relevant oligomeric MIAs. Their findings lay the foundation for further studies of this family of molecules.
The Probiotic Breakthrough for Natural Anxiety Relief and Better Mental Health
A surprising gut-brain discovery suggests that anxiety could one day be treated with specially designed probiotics. Could anxiety be shaped, at least in part, by tiny organisms living in the gut? Research from Duke-NUS Medical School and the National Neuroscience Institute of Singapore points to
Can Marco Rubio convince Trump that a free Cuba is America First?
As Secretary of State, Marco Rubio has been a primary driver of President Trump’s foreign policy. But Cuba is his most personal challenge yet. And as he plots another potential run for the presidency in 2028, it’s the one whose success or failure could most closely define him.
University of Southern Miss to add new science research facility
HATTIESBURG, Miss. (WXXV)- The University of Southern Mississippi plans to add a new state of the art science research facility on the Hattiesburg campus. The Mississippi legislature appropriated $30 million to help make this transformative project possible. This investment will support research and discovery across the biological, biomedical, and environmental sciences while strengthening the university’s position as one of the...
Focus Entertainment Reveals ‘BioEden’ Coming to PC this September, Console Release to Follow Later
A cozy solarpunk management game was announced earlier today and it looks incredibly cute! Today Focus Entertainment and Broken Arms Games are delighted to u
Ancient Chinese medicine could transform hair loss treatment
A traditional Chinese medicinal root used for over a thousand years is attracting new scientific attention for its potential to combat hair loss. Studies suggest Polygonum multiflorum can block harmful hormones, activate hair-growth signals, protect follicles, and boost blood flow to the scalp. Researchers say the herb’s effects align remarkably well with both ancient descriptions and modern hair biology.
D‑day’s secret weapon: How wetland science stopped Normandy landings from getting bogged down
Beneath the roar of gunfire and the chaos of D-day, an unlikely hero played a vital role — wetland science. Often overlooked amid military strategies and troop movements, the study of mud proved critical to the success of the largest amphibious invasion in history.
Trump says he wants Pulte to further slash staffing at national intelligence office
President Donald Trump said Friday that he wants his new acting director of national intelligence, Bill Pulte, to cut the office, which has already been significantly scaled back during his second term.
Diabetes researchers ejected from conference after criticizing White House
The scientists, including the editor of a leading journal, were handing out copies of an editorial criticizing the Trump administration’s handling of biomedical research.
A Critical UV Legacy: A Hubble Roadmap for HWO Science Readiness
The Habitable Worlds Observatory (HWO) will provide the first opportunity to directly image and spectrally characterize terrestrial exoplanets
HERMES: HiERarchical Modelling for Exoplanet Science
ESA's Ariel Space Mission will characterise the atmospheres of approximately 1000 exoplanets to quantify population-level trends.
Biophysical Society Condemns OMB Proposed Rule to Politicize Science
BETHESDA, MD – The Biophysical Society condemns the Office of Management and Budgets (OMB) Notice of Proposed Rulemaking (NPRM) on Federal Financial Assistance, released Friday, May 29th. The NPRM is a sweeping overhaul of federal rulemaking and oversight, removing individual oversight from federal agencies to promulgate rules and oversee how regulations are implemented and enforced internally.
What science has learned about living longer in the last 10 years
From the gut microbiome to the mechanics of cellular aging, here is what a decade of longevity research has revealed about how and why we age
E-bike safety; lung cancer treatment and prevention; keeping CMA Festival attendees safe; plus other stories with Vanderbilt Health sources
WKRN News 2 interviewed Jeffrey Upperman, MD, FACS, Professor and Chair of the Department of Pediatric Surgery and Surgeon-in-Chief of Monroe Carell Jr. Children’s Hospital at Vanderbilt, about e-bike related injuries following the recent death of a Brentwood High student and a proposal to require safety training before students could ride a bike on a school campus in Williamson County. Fabien Maldonado, MD, MSc,Professor of Medicine and Thoracic Surgery, was on WTVF News Channel 5‘s live studio show, “Openline,” with host Ben Hall, to discuss lung cancer, treatment and prevention. WSMV’s “Today In Nashville” program hosted Vanderbilt LifeFlight paramedic/flight nurse practitioner Tony Smith to talk about safety for the CMA Festival. The New York Times reporter Carl Zimmer interviewed James Crowe, MD, Director of the Vanderbilt Center for Antibody Therapeutics, for a story about the race to find vaccines and treatments as Ebola spreads. The Vanderbilt Health News release about the pilot clinical trial conducted by Vanderbilt Health and Cumberland Pharmaceuticals Inc., that confirms the safety of ifetroban and supports the further development of the drug to prevent cancer metastasis, was picked up by Reuters, Stock Titan,and others. Women We Admire has named Lee Ann Liska, President and Chief Operating Officer, to its list of top women leaders of Nashville for 2026. Radiology Business, Aunt Minnie, Bioengineer, and Imaging Technology News covered the study from Consuelo Wilkins, MD, MSCI, the Mildred Thornton Stahlman Professor in Rural Health and professor of Medicine in the Division of Geriatric Medicine, that found Black and Hispanic people, while known to be far more apt to have dementia, are significantly less apt than other racial and ethnic groups to show Alzheimer’s pathology on brain scans. STAT News interviewed Deva Sharma, MD, Transfusion Medicine & Hematology-Oncology, for a story about more patients requesting unvaccinated blood and what it means for the medical system at large. Yahoo! Health reporter Korin Miller interviewed Gitanjali Srivastava, MD, Director of Obesity Medicine, for a story about how semaglutide and tirzepatide compare. William Schaffner, MD, Professor of Preventive Medicine, was quoted by several news outlets about public health issues, including: NBC News (new COVID vaccinations); Medscape (pneumonia and sepsis); and CNN (protection from contagious viruses). Shelbyville Times-Gazette is repurposing Jessica Pasley’s July 2025 Vanderbilt Health News story on tick-borne illnesses as a front-page story.
Grosso poised for Fiorentina coach's job after leaving Sassuolo
Fabio Grosso has resigned as coach of Sassuolo, the Serie A club announced on Friday with reports he is now set to join Fiorentina. "Sassuolo have reached an agreement to terminate the contracts of first-team coach Fabio Grosso and his staff," the Serie A club said.
In the Smoky Mountains, a volunteer effort aims to document every species
For citizen scientists, counting thousands of species is one way to monitor climate change in America's most biodiverse national park.
French-Iranian Persepolis author Marjane Satrapi dies of ‘sadness’
Satrapi's autobiographical novel was born from her experiences of Iran's Islamic revolution and war with Iraq.
In a First, Scientists Precisely Edit Human Embryo Genes
Researchers relied on a newer gene-editing technique that may make it possible to engineer embryos, a prospect that has long alarmed bioethicists.
Meta Silently Added Face-Recognition Code for Its Smart Glasses to Millions of Phones
Code reviewed by WIRED uncovered an unreleased face-recognition system embedded in Meta’s smart glasses platform. It’s designed to identify people via biometric data stored on users’ phones.
Scientists Are Taking Improv Classes So People Will Trust Them More
What does it look like when biologists and physicists do comedy? We sat in on a session.
Website reviews Barba's spell at Galo so far
Argentine coach Eduardo Domínguez has completed 100 days in charge of Atlético-MG. The assessment of this start to his tenure is considered positive behind the scenes. The coach secured the team a p...
Gender identity, or women’s sports? There is no middle ground.
It is June again. That means another collision between Pride Month and Title IX Month, and another round in the clash between biological sex and gender identity. As they have been for years, studen…
Where science meets fashion: Raha Saremi turns agricultural waste into biomaterials
[vc_row][vc_column][vc_column_text css=”” el_id=”text-container first-paragraph” el_class=”text-container first-paragraph”] When cracking a pecan, most people throw away the shell. Raha Saremi wants you to wear it. How? As a material scientist in the College of Family and Consumer Sciences, Saremi witnessed firsthand the sheer volume of agricultural byproducts going to waste across Georgia’s farming communities and natural environment. … Continue reading “Where science meets fashion: Raha Saremi turns agricultural waste into biomaterials”
Goethe never knew this 40-million-year-old ant was hidden in his collection
Scientists examining amber from Goethe’s personal collection discovered three hidden fossil insects, including an extinct ant preserved in extraordinary detail. Advanced 3D imaging allowed researchers to see not only the ant’s outer features but also structures inside its body. The findings offer new clues about the species’ biology and suggest it likely built large nests in trees.
Rubio torches Democrat after bizarre hearing questions about his shoes: 'Is this a circus?'
Secretary of State Marco Rubio called a House Foreign Affairs Committee hearing "a circus" after Democratic California Rep. Sara Jacobs questioned him about shoes gifted by Trump.
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Human Research, Biotechnology for Advanced Health Fill Station Research Schedule
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WATCH: Rubio questioned on Mideast talks, Trump resting in meetings, Greenland control
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Trump Suggests Vance and Rubio Should Run Together in 2028 Election
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Elections to top science bodies test Croatia’s gender equality in research
Croatia’s track-record on gender equality in science has been both questioned and lauded in recent months, following both bad and good news on the topic. On the one hand, a senior awards committee was announced without a single woman researcher included. On the other, the national science academy welcomed its first cohort of fellows with more women than men.Members of the committee, which gives national awards recognising scientific achievement, are proposed by the ministry of science and endorsed by the parliament. The current line-up does include a woman, but she is culture minister Nina Obuljen Koržinek rather than a researcher. Even then, she didn’t make it into the photograph released to announce the appointments on April 16. “The image speaks a thousand words,” says Tanja Rudež, a science journalist for Jutarnji List newspaper. “I am surprised that none of these men, all well-known scientists, saw a problem with the fact that there was not a single successful female scientist on the committee,” she told Science|Business.Ivan Đikić, a prominent Croatian biochemist based at Goethe University Medical School, commented on LinkedIn that the news illustrated a “sad truth” about the state of science in Croatia.“It [. . .] reveals a system where women, despite contributing a substantial share of high-quality, internationally competitive science, are systematically excluded from the very processes that determine recognition and influence,” he wrote. Some 60% of researchers in Croatia are women, according to the Croatian Bureau of Statistics, and they perform well in international competitions. For example, of the 12 European Research Council (ERC) grants awarded to Croatian researchers, seven went to women.“So how is it possible that decision-making bodies are still dominated by men over 60, while not a single female ERC laureate is involved in the selection process?” asked Đikić. “This is not a marginal oversight; it is a structural failure.” The ministry of science did not reply to a request for comment. The awards committee is not unusual. For example, a scientific advisory body announced by the ministry of demographics in April comprises 35 men and five women. The board of the Croatian Science Foundation, newly appointed by the parliament, is a little better, with five men and two women, but still unequal. “This is especially significant because such bodies do not merely distribute prestige. They shape research priorities, funding allocation and long-term scientific development,” Marija Lugarić, chair of the parliament’s committee on gender equality, told Science|Business. “Representation here matters not only symbolically, but materially.”Referring to the awards committee and the board of the science foundation, Lugarić says that while both bodies were appointed by parliament, neither met the minimum 40% gender balance threshold that Croatian law and EU guidelines expressly recommend for public bodies.Đikić wants to see EU institutions put pressure on the government to ensure basic standards of fairness, transparency and democratic governance in science policy are met. “Meaningful change will not come without pressure,” he wrote. “It must intensify both within Croatia and at the level of European institutions. Anything less undermines the credibility of Europe’s commitment to excellence and inclusion in science.”Rudež also underlined the importance of talking and writing about this topic, “because public opinion in Croatia does influence changes in the status and visibility of women in science.”The European Commission has not yet responded to a request for comment.Good news from the academyA more positive story came from the Croatian Academy of Sciences and Arts on 21 May, with the announcement of seven new women fellows and five men. This is the first time in the academy’s 165-year history that women have outnumbered men in a new intake.One of the new fellows, two-time ERC grantee Iva Tolić, credits the academy leadership with trying to be more modern and inclusive, representing the whole community better. “The academy is really aware that so far, before this election, there were very few women,” she told Science|Business. “So, they are actively trying to make this more equal.”Related articlesExplained: How the MSCA is close to achieving gender balanceCall for EU to leverage academic freedom in global talent raceRudež is more cautious, noting that despite the academy’s “breakthrough this year [. . .] it is still a predominantly male institution, with only 18% women.”This reflects a wider imbalance in Croatia’s research landscape. “The key levers of power in science are still in the hands of men,” she went on. “For example, all 14 rectors of private and public universities are men.”Similarly, Lugarić says a structural glass ceiling still exists in Croatian science, which is “most visible precisely where power is exercised.”She cites data from the Commission’s She Figures 2024 report, which shows that Croatia ranks second in the EU for gender equality in research and innovation overall, with an equality index of 79.6 out of 100. It is in the top five for women’s career advancement, participation in research; representation across all research sectors and for scientific publications.In stark contrast, it ranks second to last when it comes to women in decision-making positions in science. “This is not a coincidence,” Lugarić says. “It is a structural pattern.”Informal barriersThe persistent under-representation of women in the highest structures of Croatia’s academies, boards, award committees and leadership positions is not down to formal barriers, Lugarić says, but arises from more subtle obstacles such as “informal networks, persistent expectations regarding traditional gender roles and the unequal distribution of care responsibilities.”Tolić would like to see more support for young women in terms of affordable housing and child support, and higher salaries. Currently, she says, salaries in science stay low for the first 10-15 years, while housing and spaces in kindergarten are limited and expensive. “You have to work a lot, you get very little money, so it’s not great to have a family in this situation,” she says.But despite the challenges, Tolić is optimistic, saying that gender equality in research in Croatia is “definitely improving and going in the right direction.” The situation is particularly promising in biology, she adds, where most full professors, heads of department and deans of faculties are women. Lugarić, too, see the glass ceiling “very slowly, cracking,” and cites the academy election as an example that structural change is possible. Yet the situation in the national awards committee is a “stark reminder that without a conscious, systemic commitment to gender balance, progress will remain slow and uneven.”
From atomic chaos to custom materials
Argonne researchers show how a class of 2D materials called MXenes can be designed atom-by-atom by tuning composition, atomic order and surface chemistry, opening paths to better materials for energy storage, electronics, shielding and biomedicine.
The cult of objectivity has broken consciousness science
With 22 competing theories and no consensus in sight, the science of consciousness is lost. In this exclusive IAI interview, Berkeley psychedelics researcher and bestselling author of a new book on consciousness Michael Pollan insists that even though consciousness lies beyond traditional forms of scientific investigation, we should resist becoming dualists who see it as something radically different from ordinary stuff in the world. Instead, he makes the case for reimagining science itself: it must stop reaching for objective descriptions of physical reality, and instead embrace subjectivity as the indispensable core of all inquiry. Alasdair Craig: How did your experiences with psychedelics get you interested in consciousness?Michael Pollan: One of the things that happens on psychedelics is that they foreground consciousness. What formerly seemed perfectly transparent and ever present—and yet, non-existent, as water is to fish—suddenly you see it. The metaphor I use in the book is that psychedelics sponge the windscreen. Suddenly you realize: wow, there’s a windscreen, there is this phenomenon that’s mediating my relationship to reality. This is not an unusual realization on psychedelics. I think a lot of people are called to think about consciousness after psychedelic experiences. So that was the proximate inspiration for A World Appears: A Journey Into Consciousness (2026).And then there was a more specific way in which psychedelics influence the book. That was a particular experience I had on psilocybin. I had the sensation that the plants in my garden were conscious and returning my gaze, with their own point of view and agency, and I got curious as to how to evaluate an insight like that. I mean, what’s the truth quotient of insights you have on psychedelics? And I was reading William James—who, of course, wrote beautifully about mystical experience—and he said, we can’t judge the metaphysics here, but we should pay attention to two criteria: (1) How useful is it to think this is true? He was a pragmatist, of course. And (2) can we subject it to other ways of knowing to validate it? Because maybe we should treat these insights as hypotheses. And that’s kind of how I approach psychedelics, as a great generator of hypotheses, but they need to be tested against other ways of knowing. And so that led me down this long path exploring the science of plant intelligence and plant sentience.AC: I love your phrase, “smudging the windowpane of conscious experience.” So do you now start to think, actually, even when I’m not on psychedelics, I’m just seeing a screen all the time, which is not reality, but rather is my conscious experience, behind which reality is hidden?MP: Well, you know, not when I’m brushing my teeth and making breakfast! But yes, in meditation, certainly. I mean, one of the things you realize is that my experience happens to be this way now, but it could be another way. And many things can affect it. My morning coffee changes the screen in various ways, sharpens certain things.___The only tool we have to understand consciousness is consciousness.___There’s this wonderful metaphor in Aldous Huxley’s book, The Doors of Perception, where he thinks we channel consciousness, and that what the brain does is edit it, and there’s a reducing valve. And psychedelics open the reducing valve wider. I don’t know that I’m ready to buy into the idea that consciousness exists outside brains, but I do love that metaphor because there are times when you are more conscious than others. I know I’ve switched from window pane to valve, but you know, a camera aperture can open wider or narrower. And I do have a sense of that. I have a sense of when I’m being less conscious, and when I’m being more conscious, by which I mean, you know, more present, taking in more sensory information. So when you start thinking about consciousness as a matter of degree, that changes things also.I think when we scroll on social media, obviously, we’re conscious. But minimally so, because we don’t have to generate our own thoughts. We’re basically taking these little hits from other people and thinking their thoughts.The process of writing this book made me kind of relativize everyday consciousness as just one type, which is exactly what William James said. Normal consciousness is one type, separated by the flimsiest of screens from the other types.AC: If we stick with the metaphor of the smudge on the window that you get when you take psychedelics, it seems like we’re saying that consciousness has become like an object that you’re looking at, right? You’re looking at the smudge and that just is consciousness. But sometimes we’ll talk about consciousness as a state that you’re in, rather than an object you can perceive. You’re either conscious or you’re not conscious. So it’s difficult to really know what sort of thing we’re talking about when we talk about consciousness, right?MP: Yeah. When you say that consciousness is an object, what’s the subject? Consciousness also? The only tool we have to understand consciousness is consciousness. So we’re in a closed loop and when we get a perspective on consciousness, we’re not achieving any distance from it. That’s one of the problems with studying consciousness. Science is predicated on an objective, God’s eye view of things, and you never get that. There’s no such thing. SUGGESTED VIEWING The brain filters consciousness With Àlex Gómez-Marín But, yeah, there is this sense, I think, that consciousness is something you can approach. Certainly, when you’re writing and trying to recreate a conscious experience, it’s a fiction, but you’re standing back from it, and looking at it. But there’s no real subject-object distinction.AC: That’s so interesting, because when philosophers start talking about consciousness, they often talk about what they call “qualia”, which is their word for the felt experience of, say, the color red. And I think that way of speaking often makes us think of the qualia as an object, which you can see out there: the redness of red. But, as you say, we also want to collapse the subject-object distinction when we talk about consciousness. So there’s something strange going on here…MP: Oh, yeah, there are many strange things going on! *AC: Let’s talk about the varieties of consciousness. Apart from perceptions, there are, pains, emotions, thoughts, and so on. What is it that holds all this diversity together so that they all count as instances of consciousness? What is it that they all have in common?MP: Yeah, that’s a really good question. I mean, there is sensory information, right? Which we perceive coming from the world outside ourselves. And then there’s internal information, which is what’s called interoception. And this is very important too. This is where feelings come from—what are sometimes called homeostatic feelings—that are intended to get the brain to keep us in these narrow ranges of temperature and glucose and so on. That’s a very important part of consciousness. And according to some researchers, who I think are probably right, this is where consciousness begins, with these very primal feelings, like hunger and thirst and warmth and itch, and things like that. And then there’s this third thing, which is our thinking about thinking.And what holds all this together is, I think, the sense of self. Consciousness generates a self: it is probably an organizing principle. All this stuff is happening to the self. It’s a construct, I think, but it is very useful. It can connect all these different streams of consciousness to a single being or a place, metaphorically speaking.* AC: The first half of your book is about the science of consciousness. Is consciousness just another thing, like black holes or the origin of life, which we don’t yet understand, but which we should have every hope that science will one day get to the bottom of, or is there something special about consciousness that makes this unlikely?MP: It depends how you define science. As we define science now, it’s going be very difficult. Science since Galileo has had a set of rules or assumptions, which is that the proper remit of science is to deal with the objective, quantifiable, third-person world. And the physical sciences have done amazing work under that set of limitations. Galileo—for tactical reasons, not for philosophical reasons—said science should not deal with the soul, which at the time was what consciousness was considered to be. So what is subjective, what is qualitative, what is first person, we’re going to leave to the church, he said. And this was a good agreement, and it probably kept many scientists from getting burned at the stake. But it leaves science in an awkward spot, now that it wants to venture into that territory of qualities, of first-person experience. And I don’t think it has the proper tools. I think it will have to add to its toolkit in some way, and find a way to bring in phenomenology, or lived experience and introspection, which science is usually dismissive of.The challenge—we alluded to it earlier—is that the only tool you have to study consciousness with is consciousness. And what I mean by that is, the whole scientific enterprise is a manifestation of consciousness. As much as scientists like to flatter themselves with this idea that they attain a godlike perspective on what they study, when it comes to consciousness, there’s no such thing. And it’s fine for all the things you can step outside of and study from that perspective. But two areas it won’t work are consciousness and cosmology.___It could be that we live in this anomaly of not believing nature is conscious. And maybe psychedelics are teaching us something we’ve forgotten.___With cosmology, too, you have to study the universe from inside the universe. It’s not that cosmologists haven’t made progress. We know a lot about the age of the universe and expansion and things like that. But we can’t penetrate what happened before the Big Bang. We just don’t have the tools because we can’t stand outside.The fact that there are 22 full-scale theories of consciousness tells you all you need to know: we’re kind of lost. And I was surprised to find that we are more lost than I thought we were when I started this. I thought that there’d be leading theories, or that we had experiments that we could conduct that would nail some of this down. And the fact is, we don’t.So, I don’t know if science can solve it. But, of course, we can change the rules of science. A really influential book for me was a book called The Blind Spot, by two physicists, Marcello Gleiser and Adam Frank, and a philosopher, Evan Thompson. It’s a reminder that science is a social practice. It’s organized in a certain way and it can be organized in a different way. But it has this huge blind spot at the center of it, which is its failure to recognize that it is a form of consciousness itself, and it doesn’t have a good way of taking account of lived experience.AC: On the one hand, I think you want to resist traditional dualism, which would say that consciousness is something magical, something supernatural, right? But on the other hand, you’re accepting that there is this division in reality between the stuff that you can investigate objectively and measure, and so on—the stuff that science has been good at finding out about—and consciousness, which, for some reason, you can’t objectively measure. Some would take this to suggest that the dualism is actually right. Is there a way of reconciling these two strands of your thinking?MP: To call it magical is full of value judgement. I mean, you could just say immaterial. The interesting thing is, I think, that intuitively we’re all dualists. And I don’t know whether that’s because we’re children of Descartes and other cultures are less dualist than we are. Or it may be because that’s how consciousness feels. It feels different than the body. It feels separate from the body. But I don’t think we should trust that intuition.AC: So let’s think about ways that science might be changed to get at consciousness. I suppose the starting point would be the way that you begin the second half of your book. You have this nice line from William James, where he says, “We now begin our study of the mind from within.” Could you give us some sense of the ways of studying the mind from within? What does this involve?MP: I don’t know what that science looks like. But one of the points I’m making is that it depends on the humanities. I found that I learned as much, if not more, about consciousness, from reading novels and poetry. There is a sense of the fullness and complexity of consciousness that you don’t get in any scientific account. I interviewed this stream-of-consciousness writer and I approached her as an expert on consciousness, and she is. So I think that dialogue is really important.I’m reading Ben Lerner’s new novel, Transcription. Just read the first page of this novel: it’s a man falling asleep on a train, going to conduct an interview, and there is the experience of being in the train, facing backwards, there’s the view outside, but there’s a reflection of himself through which he’s seeing outside. There’s the memory of dropping his kids off at school. All this is going on in one moment of consciousness. Scientists aren’t going anywhere near that. But I think it’s useful for them to think about. That’s where we’re trying to go: like, how does such a layered experience happen? You know, it also makes you wonder, could a computer ever do this? And it gives you some doubt.*AC: Before we get to computers, perhaps we could talk briefly about plants. How did you come to feel that they are sentient?MP: Well, it was a psychedelic experience, and it’s not unusual on psychedelics. In fact, there’ve been studies about how people become animists during psychedelic experience. Their belief in animism arises after a single psychedelic experience.You know, most scientists would say this is all a myth. But we have only 400 years of the age of enlightenment and science. Before that, we were animists, and if you go around the world, most indigenous cultures are still animists, and children are animists, by and large, until they go to school. So it could be that we live in this anomaly of not believing nature is conscious. And maybe psychedelics are teaching us something we’ve forgotten.As I said, I wanted to test this idea, and see whether there was conventional scientific evidence for it. And there’s fascinating work going on in a field that calls itself—in a rather cheeky way—plant neurobiology. These are people who fully realize there are no neurons in plants, but they’re trolling conventional botanists! And they’re doing experiments that are demonstrating that plants can learn and remember, which is kind of amazing: how do you store a memory without neurons? They’re finding plants that can solve problems, that can hear and see. In fact, they have 20 senses to our five or six. For example, a bean plant looking for something to twine, and given a pole within eight inches or so of it, knows where that pole is and will aim its spiraling reach at that pole. What is that about? Is it bouncing signals off of it?One of the spookiest things is the fact that the same anesthetics that put us out put plants out. You might think that plants are already out, but they’re not. They’re just slow. If you take a plant with a fast behavior, like a Venus flytrap, and give it an anesthetic, it will stop reacting. So you have to ask yourself, what is lost when the plant is anaesthetized? Some state of alertness, of awareness, of its environment, of reactivity. I’m not prepared to call that consciousness, but maybe it’s sentience—which is a simpler form of consciousness, and involves the ability to sense what’s going on in your environment and assess what’s good and bad for you and act appropriately. That may be a universal quality of life.AC: Let’s turn from plants to AI. You point out that LLMs are trained on the internet rather than direct interactions with reality. You put this really nicely when you say the internet is not the world so much as a shadow cast by the world. So LLMs are living in this kind of shadow world, or in Plato’s cave, as you put it. What’s the significance of this for AI consciousness and moral consideration? And, to recall the beginning of our conversation, if we’re stuck behind a veil or screen of consciousness, are we also stuck in a kind of shadow world?MP: I don’t think they’re the same shadow worlds because our world includes nature and other people. And even if it’s mediated in some ways... There is a reality out there, and we are in relation to it, through consciousness. There’s friction with it. What’s missing from the LLMs is that friction with the real world. There’s more to the world than human representation, which is what they’re dealing with. And that means that so far, AI is a cultural technology for combining thoughts we’ve already had. SUGGESTED VIEWING Cracking the code for thought With Roger Penrose, Sabrina Gonzalez Pasterski, Max Tegmark, Güneş Taylor Genuine creativity is more than collage. A lot of what AI does now is tantamount to collage, putting this with that and you know, that’s part of art, certainly. But there are also genuinely new ideas that come into the world that don’t come in through manipulating the representations we already have. So it remains to be seen whether AIs can be truly creative in that more radical sense.But my arguments against AI becoming conscious have to do with the fact that the idea of AI consciousness is based on this faulty metaphor that the brain is a computer. There are dimensions in which the brain is like a computer—it certainly does its share of computation. But computers have this sharp distinction between hardware and software, and brains don’t. In a brain, hardware and software are identical. Every memory is a physical change to the brain. Brains are not interchangeable in the way computers are. So this idea that you could take the consciousness out and somehow run it on another substrate, a silicon substrate, seems foolhardy.Anyway, it’s a more extended argument, and I may be wrong. And when we move to computers that aren’t based on silicon—neuromorphic computers and things like that—all bets may be off.AC: Regarding your point about LLMs being stuck in the world of our representations—the internet or whatever—and not being able to interact with reality, are these representations, the world of the internet, themselves part of reality? We’ve created the internet, but it’s still a real thing that exists. And so while the LLMs may be trapped within that part of reality, they’re nevertheless within reality and interacting with it and so on. So it’s not obvious that there’s a barrier there to them becoming conscious and being creative.MP: Yeah, I mean, if our consciousness is built out of human culture, which is what we’re talking about with all those representations. But I tend to think consciousness comes a bit more out of nature and friction with the natural world, but...AC: So there’s a fundamental divide between the natural world and human artefacts?MP: And we lose track of that, and especially people in this computer world. You know, the people who are creating these AI systems, my guess is they’ve been into video games since the age of three, and they didn’t go outside a lot. And their own contact with nature is somewhat limited. I could be wrong, it’d be a very interesting thing to ask, all the wizards of AI, whether they like to go fishing and hiking and do things like that. Or were they on computers from a very early age? I interviewed Blake Lemoine, the Google engineer who came to believe that LaMDA, the Google LLM out at the time, was conscious and deserved personhood. It was very clear that he didn’t see a distinction between this bubble in which he lived and the real world. And I think we’ve all been distanced from the natural world, and this is taking us even further away. But it’s still there, you know, and we still have bodies, and we’re still mortal, and we don’t live in a simulation.AC: I think that’s a great place to finish. Michael Pollan, thank you very much!
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