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Trump makes stunning first-of-its-kind cash promise in bid to rally GOP voters at Dallas midterm convention
President Donald Trump promised a $5,000 "Trump dividend" to every adult citizen if Republicans keep Congress at the GOP midterm convention.
Trump tries to energize his base by placing himself front and center: ‘I’m on the ballot’:
Trump spoke on the first night of the convention in Dallas, where he also promised — without specifics — that Americans would receive dividend checks if Republicans keep Congress.
Sydney Sweeney strips down for provocative new ad campaign
The “Euphoria” actress bares it all to promote Novig, a sports prediction market.
Sydney Sweeney strips down for provocative new ad campaign
‘Euphoria’ actress Sydney Sweeney strips down for provocative new ad campaign promoting Novig, a sports prediction market: ‘No betting on wars or deaths, and no politics.’
SepticSmart Week features free webinar promoting septic maintenance, public health, water conservation and more
For SepticSmart Week, learn more about Michigan’s Septic Replacement Loan Program and a free webinar for homeowners.
Sen. John Fetterman makes a surprise cameo praising Republicans at the GOP convention
The Democratic senator appeared on video promoting the efforts of President Donald Trump and Sen. Dave McCormick in shaping the U.S. Steel deal with Nippon Steel.
Viral storm video at Milford Farmers' Market prompts community support for impacted businesses
Missouri’s congressional map is back before the U.S. Supreme Court
The maps have prompted a series of conflicting court rulings
Chernin Entertainment Expands Film Team
Chernin Entertainment's robust film vertical has made three promotions and a new hire.
With AI memes, Trump promotes mythical version of himself as challenges stack up ahead of midterms
In the real world, President Donald Trump is struggling to stop inflation, rout the Iranian government and restore American manufacturing with tariffs. It's a different story in the fantastical vision that he shares with supporters on social media.
60 Posts in 10 Hours: How Trump’s Social Media Reflects His Version of Reality
With an assist from A.I., President Trump offers a window into how he wants to be seen — and, critics say, a barometer of his mental state.
Enjoy the wins, LSU fans, as college sports crumbles before our eyes
The Tigers’ dominance on the field and Kiffin’s loose cannon antics might provide a nice distraction in the coming months, but let’s not be lulled into believing they aren’t evidence of a structure with a severely compromised foundation.
Georgia Fans Are Absolutely Furious About This
Georgia football fans will pay for a lot of things. Tickets. Parking. Donations. Merchandise. Streaming subscriptions. Apparently, game highlights are next. Georgia promoted its traditional “Victory Highlights” video following its 63-3 destruction of Tennessee State , except there was one massive catch. The full video was placed behind the Glory Glory subscription service, which starts…
Never Forget: Advocates question pace of hiring for 9/11 survivor health program
A promise to fix staffing shortages in a program for 9/11 survivors is being questioned this week. Advocates say rehiring positions cut in 2025 is not happening fast enough for those who are sick and applying for the World Trade Center Health Program.
UT San Antonio prepares biomedical researchers for entrepreneurial innovation
UT San Antonio is preparing biomedical researchers to think beyond scientific discovery, equipping them to consider how promising research can move from the laboratory toward real-world impact.
Scientists Discover the Earliest Evidence of Drug Use in Really Old Teeth
A hunter-gatherer who lived in Indonesia as early as 25,000 years ago may have regularly sucked on betel nuts to release their psychoactive properties.
AirPods 5 Announced With Improved Noise Cancellation, Audio Quality, and More
Apple today introduced AirPods 5, bringing Active Noise Cancellation to its entry-level wireless earbuds at a starting price of $129. Apple says AirPods 5 remove up to 50% more external noise than AirPods 4 with Active Noise Cancellation. A redesigned acoustic architecture and updated Adaptive EQ also promise richer, more detailed sound, while an improved Transparency mode makes nearby voices and sounds more natural.
iPhone 18 Pro Has Apple's Fastest Lens Yet Thanks to Variable Aperture
iPhone 18 Pro promises to be Apple's best iPhone camera ever. By a lot.
Jake Paul Teases Michael Page Signing for MVP MMA
Fight promoter Jake Paul teased a potential signing of former UFC fighter Michael Page to the MVP MMA roster.Page completed his six-fight UFC contract with a unanimous decision win over Nursulton Ruziboev at UFC Paris. However, he was heavily criticized by fans for putting on another boring fight, which was not the first time he’s […] The post Jake Paul Teases Michael Page Signing for MVP MMA appeared first on HEAVY.
Johnsonville Votes For Sausage Over Political Ads - Midland
Johnsonville has jumped back into electoral politics, this time asking people to vote for something sensible: affordable protein for dinner. The humorous campaign targets viewer fatigue, as record spending on political ads threatens to drain the fun out of every last game, sitcom and streaming pleasure. This time, the company is throwing its hat in the ring for Dinner 2026. Backed by research it conducted with Harris Polls, Johnsonville has learned Americans are already overwhelmed by both politics and meal planning. Sausage is running the dinner race on a core promise to simplify dinner decisions, the company says.
Rabies testing concerns prompt investigation from Minnesota health officials
The Minnesota Department of Health is searching for customers of a Twin Cities company that it suspects has not been consistently submitting rabies tests for testing.
Building a stronger workforce through inclusive hiring
ARC Ontario promotes inclusive hiring in New York to strengthen workforce by employing people with intellectual and developmental disabilities.
Don’t Promote Them. Talk to Them.
Pay matters, but conversations keep people. Brian Walch explains how to build a "Career Compass" to retain your team.
Bucs $14M Addition Expected to Have ‘Prominent’ Role
One of the tougher fantasy football backfields to decide is the Tampa Bay Buccaneers. While many will be debating between Bucky Irving and Kenneth Gainwell as the top option in fantasy, Greg Auman of Fox Sports weighed in with a strong case for Gainwell. Auman noted that Zac Robinson has a chance to significantly improve […] The post Bucs $14M Addition Expected to Have ‘Prominent’ Role appeared first on HEAVY.
John Malkovich cancels performance in Israel over fabricated quote circulated by promoters
John Malkovich has canceled a planned performance in Israel after promoters circulated a false quote attributed to him.
John Malkovich cancels performance in Israel over fabricated quote circulated by promoters
John Malkovich has canceled a planned performance in Israel after promoters circulated a false quote attributed to him | KCBS All News 106.9FM and 740AM
John Malkovich cancels performance in Israel over fabricated quote circulated by promoters
John Malkovich has canceled a planned performance in Israel after promoters circulated a false quote attributed to him | WBEN
Browns cornerback Denzel Ward joins Guardians’ ownership group
The Macedonia native is the second prominent athlete from Northeast Ohio to buy a stake in the Guardians this year, joining Travis Kelce.
Scientists Who Study Sleep and Narcolepsy Win Prestigious Lasker Award
The two researchers have won a prestigious Lasker Award. Their findings laid the groundwork for a new drug that addresses the sleep disorder’s root cause.
Military Toxic Exposures Appear to Affect Both Mental and Physical Health in Veterans
Environmental hazards encountered during military service, such as Agent Orange and toxins from open-air burn pits, are known to be linked to adverse physical health outcomes. The VA recognizes them as presumptively service related under the Agent Orange Act of 1991 and the Promise to Address Comprehensive Toxics Act of 2022.
The Establishment Pulls Through: Five Takeaways from the New Hampshire Primaries
The U.S. Senate race will feature familiar faces: former Senator John E. Sununu and Chris Pappas, a four-term congressman. Stefany Shaheen, a senator’s daughter, eked out a win in a House primary.
Upstate Hospital opens clinic for youth who need walk-in mental health therapy
A prominent Central NY family donated $5 million to make the center a reality.
Film and TV Portrayals of A.I. Go Beyond Science Fiction
Plots involving some kind of artificial intelligence are even part of soap operas. Here’s how they’ve evolved over the decades.
Draymond Green's Klay Thompson Defense Reveals Miami Heat's Promising Plan
Draymond Green's defense of Klay Thompson offers a useful blueprint for Miami Heat expectations. Thompson's role should center on shooting gravity, off-ball movement, and complementary offense-not recreating his 2017 Golden State Warriors production. Green's Ray Allen comparison reinforces that approach after Thompson's move to Miami. What Did Draymond Green Say About Klay Thompson and the […] The post Draymond Green's Klay Thompson Defense Reveals Miami Heat's Promising Plan appeared first on S
Dana White Comments on Michael Page’s UFC Future
UFC president Dana White confirmed that the promotion has no interest in re-signing Michael Page after the conclusion of his contract.Page just finished his six-fight UFC contract with a 5-1 record, but his fights were not exciting to watch, and the UFC had no interest in re-signing him.Dana White Confirms Michael Page Is No Longer […] The post Dana White Comments on Michael Page’s UFC Future appeared first on HEAVY.
With AI memes, Trump promotes mythical version of himself as challenges stack up ahead of midterms
President Donald Trump is using memes to portray himself as powerful amid struggles with inflation and international issues.
49ers lose promising defensive lineman for the year
49ers’ Alfred Collins suffers season ending injury in Australia days before clash versus Rams
Lubbock first responders promote wellness programs to address mental health
First responders in Lubbock are highlighting department wellness programs designed to give officers, firefighters and paramedics access to mental health support.
Undefeated Anthony Wint Books Second UFC Fight in 43 Days
Former NFL player Anthony Wint has booked his second UFC fight in 43 days. The undefeated athlete out of Homestead, Florida, fights on the UFC 332 card on October 3 in Salt Lake City, Utah. He takes on promotional newcomer Lucas Armand in the heavyweight division. The UFC announced the fight on the Dana White’s […] The post Undefeated Anthony Wint Books Second UFC Fight in 43 Days appeared first on HEAVY.
Taylor Swift Promoter Tells Judge Live Nationr Could Kill His Business
Louis Messina, tour promoter for Taylor Swift's Eras Tour as well as Ed Sheeran and other top acts, told a judge Live Nation has harmed his business.
SBA promotes CHOICE Arrangements for small-business health benefits
The SBA and CMS are promoting CHOICE Arrangements, formerly known as ICHRAs, as an alternative health benefits model for small businesses.
SBA promotes CHOICE Arrangements for small-business health benefits
The SBA and CMS are promoting CHOICE Arrangements, formerly known as ICHRAs, as an alternative health benefits model for small businesses.
How Japan’s anti-immigration politics runs on imported narratives
Without a clear national immigration policy, imported populist narratives have gained prominence in Japan.
Shohei Ohtani Promises Changes Amid Injuries, Dodgers’ Slump
Dodgers star Shohei Ohtani's season took a rocky turn over the past day, with him publicly admitting that he is injured.
All North Carolina student IDs will have mental health resources printed on them as part of the Student Helpline Act
RALEIGH, N.C. (WNCN) — Today is 988 Day, a nationwide event dedicated to promoting mental health support and suicide prevention through the 988 Suicide & Crisis Lifeline, and now, in North Caro…
Small business owners feel good now, wary about what's ahead: NFIB optimism index
Small business optimism dipped in August but stayed above its long-term average as uncertainty remained elevated, prompting some owners to delay bigger investments.
Small business owners feel good now, wary about what's ahead: NFIB optimism index
Small business optimism dipped in August but stayed above its long-term average as uncertainty remained elevated, prompting some owners to delay bigger investments.
Small business owners feel good now, wary about what's ahead: NFIB optimism index
Small business optimism dipped in August but stayed above its long-term average as uncertainty remained elevated, prompting some owners to delay bigger investments.
Small business owners feel good now, wary about what's ahead: NFIB optimism index
Small business optimism dipped in August but stayed above its long-term average as uncertainty remained elevated, prompting some owners to delay bigger investments.
Small business owners feel good now, wary about what's ahead: NFIB optimism index
Small business optimism dipped in August but stayed above its long-term average as uncertainty remained elevated, prompting some owners to delay bigger investments.
Small business owners feel good now, wary about what's ahead: NFIB optimism index
Small business optimism dipped in August but stayed above its long-term average as uncertainty remained elevated, prompting some owners to delay bigger investments.
Ohio politicians keep promise to rebuke Les Wexner by donating $200K in campaign contributions
Freedom a la Cart, a downtown Columbus cafe that employs sex trafficking survivors, was one of several organizations that politicians donated to this year.
HHS Announces Key Leadership Selections at FDA to Promote Innovation, Reform, and National Health Priorities
The U.S. Department of Health and Human Services today announced the selection of four senior leaders at the U.S. Food and Drug Administration.
Exclusive: Two of gaming’s biggest names are making a big investment in gaming’s future
The first thing to know about the Nova Games Foundation is that it isn’t about The Game Awards. And it’s not about PlayStation. The ambitious new grant program is the brainchild of Geoff Keighley and Mark Cerny. Keighley is the host of The Game Awards, Summer Game Fest and Opening Night Live. Cerny is a game designer of some 45 years and the lead architect for the PlayStation 4 and 5. But this new thing, which they’re revealing through Game File, isn’t about their day jobs. It’s an unaffiliated, standalone philanthropic project. It’s a bet on the artistic future of video games and a way, they tell me, to give back. “I’m nearing the end of my career,” Cerny recently told me over email. “I’m not done yet, but paying it forward—in the best way possible—is very much on my mind these days,” The Nova Games Foundation is a university-affiliated fellowship program, intended to offer six-figure grants to 20 young game designers each year, potentially for decades to come. It will offer no-strings-attached funding along with mentorship from games industry leaders, a combination intended to aid the development of groundbreaking new games, Cerny and Keighley told me. Nova will begin accepting applications in December, from class of 2026 and 2027 students from 13 affiliated gaming programs at universities in eight countries. The schools working with Nova include the New York University and the University of Southern California in the U.S., along with Abertay University in Scotland, Cnam-Enjmin in France, TH Köln in Germany, and the Royal Melbourne Institute of Technology in Australia, Cerny and Keighley said. The plan: $100,000 per recipient, with about a quarter of Nova fellows eligible for up to $500,000 more for projects that are shaping up particularly well. Payments will be delivered based on development milestones, and recipients will own their games. Nova will help promote the work, and developers will be free to pursue the publishers and platforms of their choice. Nova can help introduce fellows to publishers, but won’t take a cut. “I’ve always wanted to give back, but given my role in the industry, I’ve never felt it appropriate to commercially invest in games,” Keighley told Game File. “I’ve never owned stock in a game company or taken a financial stake in a game. Nova is philanthropy: we aren’t taking equity or looking to recoup the grants. The return we’re hoping for is creative—helping new voices make games and find their footing. “Mark and I have each made multi-million-dollar donations to establish the foundation, and we intend to keep contributing. We hope others will join us.” Cerny and Keighley have already hired an executive director, John Maconga, and a head of grants, recent Game Developers Conference director Ashley Corrigan, to help launch the effort. They’re working to recruit game industry leaders to join the effort. Keighley says “dozens of leading game directors have already expressed interest in contributing their time.” To name one, they’ve already gotten Josef Fares, lead designer from It Takes Two and Spit Fiction studio Hazelight on board with a donation and pledge to help out. “I’m proud to support Nova because it gives the next generation of creators the freedom to explore their creativity and hopefully bring their unique visions to life,” Fares told Game File. A plan forged from a friendship Keighley and Cerny have known each other a long time. It’s been so long, Cerny isn’t even sure exactly when they met. “We travel in much the same circles and I’m sure first intersected in the 90s or early 2000s,“ Cerny said. Keighley thinks it might have been during his stint writing a column about the mid-’90s console 3DO for a gaming magazine while Cerny was working on games with Crystal Dynamics or on Way of the Warrior with Naughty Dog. They became genuine friends about a 10 years ago, Keighley said, as they bonded over a shared love of games and a hope to improve the industry. “About a decade ago, we started having dinner a few times a year in LA,” Keighley said. “Just to catch up on life and the industry. Those conversations continued over Zoom during COVID. Nova grew out of that friendship and a question we kept coming back to: ‘What could we do to help the next generation of game directors get started?’” Keighley credits Cerny with the idea to figure out a way to put their money and time back into the industry. At one of those dinners, Keighley proposed the idea of a fellowship program. He’d recalled applying for a Rhodes Scholarship when he was younger. “Spoiler: I didn’t get it,” he said. He’d admired the MacArthur Foundation’s so-called “genius grants.” He liked these kinds of programs that recognized people’s talents and gave them the financial boost and the freedom to realize their potential. With Cerny, he had pondered what a game industry version of that could be. Keighley liked the idea of centering the fellowship on students, drawing inspiration from the accomplishments of Jenova Chen, the USC game design graduate who went on to lead the creation of gently moving, ambitious games such as Flower and Journey. Keighley also thought it could be useful to help promising graduates bridge the transition from student to professional. “Joining an established studio isn’t always possible—especially in today’s market—and even then, it isn’t the right path for everyone,” Keighley said. A fellowship, he realized, could give “graduates the time, resources and guidance to pursue a game of their own and not worry about the commercial viability.” As the idea took shape, Cerny also saw an opportunity to enable more games of a certain type: “The target with the grants is games as an artistic medium,” Cerny told me. “We like to say games with ‘artistic, literary and societal value.’” He added: “I’m a pretty big gamer myself, though I tend to gravitate towards the smaller and more unique or artistic titles, games like Neva, Abzu, Gorogoa, Stray or Outer Wilds. I was just playing and Roger on a flight to Japan, and was getting misty eyed to a degree that I was concerned that a flight attendant would ask me if I was OK. “So one fun benefit here is the games that will come out of the Nova Games Foundation – I can’t wait to play them myself.” Cerny believes it will also be useful for Nova fellows to hone their craft and team leadership skills. “We are looking for the next generation of visionaries,” he said. “The trick is that they will also need to have the executive function necessary to drive a small project to completion.” Game File is a reader-supported publication. To receive new posts and support my reporting, please consider becoming a free or paid subscriber. Subscribe Going big with this Keighley and Cerny may have started Nova and may be the ones primarily backing it right now, but they’re dreaming of something that goes beyond them. “Mark and I may have helped get it started, but one of our measures of success is that Nova grows into something the entire games industry feels a sense of ownership in,” Keighley said. “Our ambition is to build a lasting endowment supported by people and companies across the industry, and an equally broad community of creators willing to give their time and experience to the next generation.” The industry has a lot of knowledge that it can pass to the next generation, Keighley said: “Nova can hopefully become a way to connect that generosity with talented young creators at the moment when it can make the biggest difference.” Cerny, who told me he believes Nova can mature “over the next 10 or 20 years,” sees an opportunity to give generations of game makers momentum. “The industry has changed immeasurably since I started in games in 1982,” he said. “These graduates have talent, training and tools that outclass what we had back in the day by an astonishing amount. But they face a tough road ahead getting traction in the industry, and many could benefit from our support. We want to be there to give it to them.” “There’s a personal side to this, too,” Keighley said. “I don’t have children, and I’ve spent a lot of time thinking about what I can do for future generations. Games have been my entire career. I’ve been incredibly fortunate, and helping someone else build a life in this industry feels like a meaningful way to give back.” Cerny’s oeuvre dates back to Marble Madness and Sonic the Hedgehog 2. He has stood on stage multiple times to reveal the future of PlayStation hardware. He’s been an executive producer for a string of modern PlayStation classics such as The Last Guardian and Marvel’s Spider-Man. Nevertheless, of Nova, he said, “It’s certainly not like anything I’ve done before.” Nova Foundation applications will be due in December and the first wave of fellows will be announced in March 2027. A full list of participating universities and steps students and recent graduates can take to apply to become a Nova Fellow is forthcoming.
The U.S. bishops are speaking out forcefully on politics—and finally being heard
Prompted by the beginnings of both Leo XIV’s papacy and the second term of Donald J. Trump, the bishops are using their voice in a new way.
Here's how parents can promote a healthy diet in kids without the unnecessary friction
Proposed Changes to Head Start Undermine Its Role in Promoting Child Nutrition and Healthy Eating - Food Research & Action Center
Published September 8, 2026 For more than 60 years, Head Start has supported young children during their most important phase of growth and development. For families with limited resources, Head Start is a trusted source of care, education, nutritious meals, and health services. Despite Head Start’s long history of bipartisan support, and demonstrated success, the U.S. Department of Health and Human Services (HHS) has a proposed new […]
Names in the News 9-8-26
Appointments and promotions at Constellation Hotels, Emirates, Virgin Atlantic and Hilton
Milan Keep Considering Appointing an Elite Director
Despite a couple of attempts, Milan didn’t bring in a new head of football in the summer and simply promoted from within after ousting CEO Giorgio Furlani and director Igli Tare. While Gerry Cardina...
AMID POLITICAL AD BOMBARDMENT, SAUSAGE DECLARES ITS CANDIDACY… FOR DINNER
As political advertising floods screens, phones and mailboxes ahead of the 2026 midterm elections, Johnsonville is entering the race for Dinner 2026 with a candidate of its own: Sausage. Backed by new research commissioned by Johnsonville suggesting Americans are overwhelmed by both politics and meal planning, Sausage is running on a core promise to simplify dinner decisions.
AZ's R&D chief Barr touts internal 'science success story' after IL-33 antibody's stellar showing in COPD
With a detailed data drop that AstraZeneca’s R&D chief described as an internal “science success story,” the British Big Pharma has secured an FDA priority review for what it believes could become a flagship biologic in chronic obstructive pulmonary disease (COPD). In detailed results from the late-stage Oberon and Titania trials—first teased in March and detailed in full at the European Respiratory Society Congress in Barcelona this week—the drugmaker laid out the extent of its IL-33 inhibitor’s potential to reduce moderate and severe exacerbations in a wide range of COPD patients still struggling with those “lung attacks,” as AstraZeneca’s Sharon Barr, Ph.D., called them, despite using standard-care inhaled therapy. In the headline results, a 300 mg dose of tozorakimab given once every four weeks curbed those moderate and severe exacerbations in the studies’ primary population of former smokers by 29% in the Oberon study and 34% in Titania. In the overall population of both current and former smokers, these reductions were 30% and 29%, respectively, versus placebo and inhaled standard of care. The benefits also extended to clinically meaningful exacerbation reductions in all prespecified patient subgroups and specifically turned up promising signals in patients across a range of blood eosinophil counts, with Barr telling Fierce that “it’s the details that make this even more exciting than the high-level results that we’ve already shared.” In fact, during AZ’s tozorakimab poster presentation at the ERS 2026 Congress this past weekend, attendees were so enamored by the data that event organizers had to encourage people to clear the room and look at the other presentations on offer, Barr said in an interview. “I think it really speaks to the fact that there is a lot of buzz around these data because the entire respiratory community has been so desperate for new therapies for these patients,” she explained. The respiratory disease continues to represent a “staggering unmet medical need,” Barr said, highlighting the COPD exacerbations that the Oberon and Titania studies homed in on, which she added carry a greater mortality risk than a heart attack. “When a patient has a severe exacerbation, only about half of them are still alive within three and a half years,” she pointed out. As for tozorakimab specifically, Barr christened the molecule “an AstraZeneca science success story,” harkening several years back to the point at which researchers began to explore IL-33 as a driver of respiratory disease, and COPD in particular. At the same time, “there was still so much that wasn’t understood,” she admitted, highlighting the insight that IL-33 signals through both ST2 and EGFR through the RAGE pathway, a discovery Barr attributed to AstraZeneca's own scientists. Understanding the need to tackle both pathways in COPD—and aware of competitor candidates in the hopper, including one that bound ST2—the company ultimately had to make some “courageous decisions,” Barr said. These included taking a prior COPD molecule offline and going back to the drawing board to reinvent its potential IL-33 label “to make sure that we had a molecule that could block signaling through both arms of the pathway, through both the reduced form and the oxidized form, knowing that we wouldn’t be first, but striving to be best.” “When we put [tozorakimab] into the clinic, we firmly believed that we had a differentiated molecule, and we saw the other molecules blocking just ST2 or partially blocking IL-33, unable to deliver two positive pivotal studies in COPD,” Barr explained. “We kept marching forward because we believed our molecule was differentiated, and now I think we have the clinical validation that supports that.” Ultimately, AstraZeneca finds itself on much better footing these days when it comes to potential biologic rivals to tozorakimab in COPD. Sanofi and Regeneron’s Dupixent, for instance, is approved to treat COPD exacerbations in patients with high eosinophil counts, but not low ones. Meanwhile, the future has become cloudier for other next-gen IL-33 candidates from Sanofi and Regeneron, as well as Roche, which have suffered trial flops in recent years. One other potential ingredient for AstraZeneca’s success in its duo of studies was that the company was “ambitious in the trial design, willing to look at an all-comers population,” Barr said, “and willing to enroll the most severe patients.” Prior studies for would-be biologics rivals in COPD “avoided enrolling” those patients, she pointed out. She also highlighted the Big Pharma’s painstaking design of exacerbations in its trial, which “gave us a very rigorous readout,” and pointed to “the extra effort and investment” the company put in to understand the effect of mucus plugs in patients. Barr described mucus production as a “key feature in disease diversity,” noting that mucus plugs—obstructing clumps of mucus that block patients’ airways—are associated with worse outcomes in COPD. In its data announcement, AstraZeneca noted that an integrated analysis of Oberon and Titania found tozorakimab “demonstrated a reduction in patients’ mucus plug score,” with the pharma claiming its biologic is the first to deliver such results in a broad COPD population. “So being able to reduce those mucus plugs, we expect, is an important part of driving benefit for patients who are living with COPD,” Barr said. Again touching on the breadth of the study populations, Barr added that tozorakimab “worked across all eosinophil levels in both current and former smokers across all levels of lung function,” which she suggested “really simplifies decision-making for clinicians, and it allows them to offer therapy to the broadest possible patient population.” In the highest patient eosinophil count group, tozorakimab helped chart a 43% reduction in exacerbation risk, which Barr stressed were “unprecedented data.” In the mid-level group, AZ’s drug delivered a 23% reduction and, in the lowest group, a 34% reduction in eosinophils, which Barr said suggests efficacy “in all patient subgroups.” As for AZ’s recent guidance upgrade on the medicine’s sales opportunity, the lift from a $3 billion to $5 billion range to $5 billion plus was informed by multiple factors, Barr said, including the fact that “in 2024, there were multiple competitors, and there aren’t anymore.” Additionally, “we know that this is a massive unmet medical need, and this is a really incredible set of data that we think will be very convincing to the clinical community,” Barr said. Looking ahead to a potential evolution of the COPD treatment landscape, Barr noted that most patients start treatment in the community with an option like a triple therapy, and for them, having an option like AstraZeneca’s inhaler Breztri will remain a “really important part” of that journey. But of the patients uncontrolled on triple therapy, which Barr described as “about half of them today,” just a “small fraction” are currently eligible for biologic therapy, which she emphasized AstraZeneca is working to change. Understanding that COPD is not a “one-size-fits-all” disease, AstraZeneca is also looking at its antibody drug Tezspire for patients with T2-driven disease, and the company continues to think about new mechanisms for tackling COPD through both systemic and inhaled drugs, Barr said.
Health care features prominently in Democrats’ agenda
Democrats are sharpening their health care plans as the midterm elections near.
Commentary: Sadly, the promise of special education still hasn’t been realized
Significant barriers prevent students with disabilities from reaching the goal of preparing them for the transition to adulthood and independent living.
Straight-Six-Powered BMW M350 Promises 440 HP and a Drift Mode: TDS
Also, Stellantis has expanded an already massive Jeep Grand Cherokee suspension recall, and the new Audi A2 is an EV we'll be sad to miss out on.
California’s political hopefuls remain silent on state’s job losses, unemployment
Dan Walters Commentary: The aspirants for those positions are making all sorts of promises to win voters’ approval. But few, if any, have mentioned a slow-motion menace affecting a fundamental
Six decades of politics (but little government)
The first aired episode of “Star Trek,” entitled “The Man Trap,” premiered on September 8, 1966 — 60 years ago today. I’m actually editing a political science fiction issue of The Forum right now, and it’s prompted to me think a lot about the ways that Trek deals with politics and government and what it’s offered us as commentary. The @smotus report is a reader-supported publication. To support this work, please become a paid subscriber. Subscribe The original TV series ran from 1966 to 1969. It had a loyal but modest following, but the audience grew substantially with the series in syndication for years after that. The franchise developed its first motion picture in 1979, followed by five sequels, and then a whole other series of films built around the “Next Generation” series that first aired in 1987. In recent decades, several more TV series have built up around it, including the current “Strange New Worlds,” now in its fourth season. Throughout the past six decades, the franchise has offered us a good many insights into US politics and international relations, although often disguised as science fiction yarns. The original series was largely a Cold War fable, with the United Federation of Planets (a stand-in for the US) perpetually at odds with the Klingon Empire (a stand-in for the USSR). The “Let That Be Your Last Battlefield” episode (1969) posited a planet divided into two races, largely indistinguishable to outsiders, but nonetheless constituting a brutal racial hierarchy. “Patterns of Force” (1968) showed a struggling planet where the leader had attempted to construct a benevolent dictatorship — literally Nazism without bigotry — and found that authoritarianism could not exist apart from hierarchy and oppression. (Relatedly, I’d put “Star Trek VI: The Undiscovered Country,” high on a list of dad films about the end of the Cold War, near “The Hunt for Red October.”) Get 20% off for 1 year Indeed, the original series itself was something of a political statement, with a multi-racial crew running the Enterprise, a diverse and largely peaceful Federation mostly free from want and oppression, and protected by Starfleet, an armed force whose scientific mission was at least as important as its military one. Famously, when Nichelle Nichols wanted to walk away from the role of Uhura on the original series, none other than Martin Luther King, Jr. met with her and urged her to remain on the show, discussing the importance of viewers seeing an intelligent Black woman as part of the command team three centuries hence. Later series in the Trek franchise offered a good deal of political commentary on their own, but probably none as explicitly and incisively as “Deep Space Nine,” which ran from 1993 to 1999. The episodes surrounding the Dominion War, especially the “In The Pale Moonlight” (1998), showed the compromises, sacrifices, and moral rot associated with winning even a just war — probably better than any series would until “Andor” (2022-25). In “Far Beyond The Stars” (1998), Captain Benjamin Sisko is somehow transplanted to the role of a science fiction writer in 1950s New York. The writer is frequently sidelined and his ideas stolen because publishers don’t want to credit a Black writer. Several series have depicted the secretive Section 31 — an unacknowledged black ops security force operating within Starfleet. These episodes often end up using Section 31 as a foil to show the dangers of a lawless group within a lawful society, even (especially) when that group posits itself as essential for everyone else’s freedom to continue. The current “Strange New Worlds” has played with a few political themes. I found the first two seasons of this show among the best that the Trek franchise has produced in decades, but this season and the last have really been struggling for ideas. Yet one interesting thread is the idea that the diplomatic and enlightened leadership style of Captain Christopher Pike will not work in all situations. “A Quality of Mercy” (2022), which I wrote about here, puts Pike in the middle of a battle with a Romulan vessel in an alternate timeline, and finds that Pike’s conciliatory style would actually make a lengthy and deadly war more likely, while a quick and more violent approach might have prevented the war. This season’s opener, “Valles Marineris,” shows a pre-lightspeed civilization locked in a war to the death with a neighboring planet. The idea of an alliance or a federation hasn’t even occurred to them — their ship’s commander is curious but doesn’t see it as an option. For a franchise as political as “Star Trek,” one thing we almost never see is the government. We get occasional glimpses of Starfleet’s council — mostly uniformed people at a rectangular table — but almost no sense of how the Federation is governed. Are there elections? Who is in the legislature? How much power does the president have? What kind of factional divisions do they wrestle with and how? The shows and films are pretty silent on this. We’ve seen a few military tribunals within Starfleet, but little about how civilians deal with crime and injustice. With recent years seeing some of the franchise’s more interesting plot lines and casts, it seems clear that Star Trek is still full of energy and ideas. Given the erosion of American democracy and the reshuffling of the international order, there’s no shortage of material for future shows to comment on. I’m not sure we should toast to 60 more years, but cheers to a show that continues to teach us about ourselves. Share
72nd Annual Decatur BBQ Fest promises flavor, fun, and free family entertainment on Sept. 12
DECATUR -- A cherished Northwest Arkansas tradition returns Saturday, Sept. 12, as the Decatur Chamber of Commerce hosts the 72nd annual Decatur BBQ Fest at Veterans Park (1105 W. Main St.).
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A.I. Models Built a Computer Worm That Could Rapidly Hack WeChat Accounts
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Port of Grandview works to attract new businesses with active marketing and land development
The BriefThe Port of Grandview is actively marketing the community to attract new business development, with efforts including attendance at trade shows and conventions like Food Northwest in Portland.The Port reports strong demand for business property, with several prospective clients currently seeking space to build in Grandview.The Port recently acquired 45 acres for its new Woodworth Road Business Park, with planning underway to support the community's continued growth.GRANDVIEW — The Port of Grandview is capitalizing on strong interest in the community by actively marketing Grandview to businesses seeking locations for expansion and growth. The Port's efforts are paying off, with increased development activity and growing demand for available business property.Grandview's appeal stems from multiple factors. The community's available land and central location between the Tri-Cities and Yakima make it an attractive option for businesses looking to establish or expand operations. The Port has recognized these advantages and is taking a proactive approach to market the community directly to potential clients.Port Executive Director Randy Tucker says the Port has been actively attending trade shows and conventions to promote Grandview as a business destination. These events, including Food Northwest in Portland, provide opportunities to connect with companies actively seeking new locations."Say, hey, locate your business here and bring your customers here. And it's worked out pretty good for us," Tucker said.The Port's marketing strategy is generating results. The Port reports strong demand for business property, with several prospective clients currently looking for space to build in Grandview. This interest reflects the effectiveness of the Port's outreach efforts and the community's appeal to businesses in various industries.To support this growth, the Port recently acquired 45 acres for its new Woodworth Road Business Park. Planning is underway to determine how the property can best support Grandview's continued development and attract additional businesses to the area.The combination of available land, strategic location, and active marketing positions Grandview as an increasingly attractive option for businesses seeking to relocate or expand. As the Port continues its efforts to promote the community, Grandview appears poised for continued economic growth and development. News Three Queens Fire approaching 10,000 acres, now 11% contained Robert Desaulniers, Josh Culbreth News Two injured after rear-end crash leads to rollover near Grandview Robert Desaulniers News Grandview High School temporarily enters secure and teach for possible altercation between students Robert Desaulniers News Port of Grandview pursues economic growth with new business park development William Albert, Apple Valley News Now News Driver dies in fiery crash in Columbia Park Friday Erin Wencl COPYRIGHT 2026 BY APPLE VALLEY NEWS NOW. ALL RIGHTS RESERVED. THIS MATERIAL MAY NOT BE PUBLISHED, BROADCAST, REWRITTEN OR REDISTRIBUTED.
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Labor Day marks end of tourist season for local businesses
While crowds filled the Carolina Beach boardwalk for Labor Day, the holiday unofficially marks the end of the coastal tourist season, prompting local business owners to reflect on their summer success.
Labor Day marks end of tourist season for local businesses
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Amazon Restocked the Rare Pokémon TCG Prismatic Evolutions Super-Premium Collection Directly, Offering a Chance to Chase the $1,500 Umbreon ex
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Yeah, three very prominent names in their sport, …
Yeah, three very prominent names in their sport, …
Trump keeps heralding an economic boom, but even a solid jobs report is causing problems for him
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New Super Smash Bros and Nintendogs games are on the way, according to prominent Nintendo leaker
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Home fortress promises winning Champions League start
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Bills Named Top Trade Destination For Promising 1,300-Yard WR
The Buffalo Bills could target Houston Texans wide receiver Tank Dell in a trade, an NFL analyst suggests. The post Bills Named Top Trade Destination For Promising 1,300-Yard WR appeared first on HEAVY.
Minersville police selling special patches to support youth mental health
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Chinese theater, promoter fined for altered patriotic song in a comedy show
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