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de Beaumont and UW-Madison Announce Transition of New to Public Health Program
The New to Public Health residency program, an innovative initiative supporting early-career public health professionals in their roles.
A Business Owner Paid Himself a Low Salary for Decades to Save on Taxes. The Trade-Off Shows Up Now, in a Smaller Social Security Check, and Selling the Company Won’t Fix It.
A 66-year-old business owner running an S-corporation for decades is planning his exit. A buyer is circling, and he expects the sale to fund retirement. When it came time for him to request his Social Security statement, the projected monthly benefit was lower than expected. Friends with W-2 careers and similar lifestyles were getting noticeably ... A Business Owner Paid Himself a Low Salary for Decades to Save on Taxes. The Trade-Off Shows Up Now, in a Smaller Social Security Check, and Selling
Cristiano Ronaldo Ends World Cup Career Without Elusive Title
Cristiano Ronaldo's quest to winning a World Cup is now over following Spain's win over Portugal in the round of 16.
Cristiano Ronaldo's World Cup Career By The Numbers
Portugal superstar Cristiano Ronaldo confirmed that this tournament will be his final World Cup appearance. Here is a look at Ronaldo's World Cup career by the numbers.
My newsletter made more than my CFO job, so I quit.
CJ Gustafson says he left a successful finance career after his newsletter business became more lucrative than his executive role.
60 summers of service: Vanderbilt Clarksville Hospital's teen volunteer tradition
Vanderbilt Clarksville Hospital's VolunTeen program has been introducing young people to health care careers for six decades.
Which NBA Stars Benefited Most From This Wild Offseason?
But if Herro stays on the floor, I think this is the best fantasy situation of his career. I'd draft him noticeably earlier than I would have just a month ago. Giannis Antetokounmpo Elite Is Still Elite Sometimes we overthink these things.
How this Olympic snowboarder is building a business career
Inside the budding business mind of a young Olympic medalist.
In pictures: Marine Le Pen’s political rise and frustrated presidential ambitions
French far-right figurehead Marine Le Pen could see her 40-year political career come to an end on Tuesday if French courts rule that she is guilty of embezzling public funds and ineligible to stand…
Explore the science behind women’s wellness in new fall 2026 course
NUTR 494: Science of Women’s Wellness explores the science behind women’s wellness, equipping them to cut through health myths and prepare them for future career paths that include women’s health and wellness.
Grealish handed City lifeline as Maresca plans assessment
Jack Grealish has been handed an unexpected chance to revive his Manchester City career.New head coach Enzo Maresca wants to assess the winger during pre-season before deciding his future, TEAMtalk re...
A timeline of Marine Le Pen's political career and the rise of the French far right
PARIS (AP) — French far-right leader Marine Le Pen’s political fate is at stake Tuesday when a Paris appeals court is to rule on whether she may be barred to run in the 2027 presidential election.
A timeline of Marine Le Pen's political career and the rise of the French far right
French far-right leader Marine Le Pen's political future is on the line as a Paris appeals court rules on her eligibility to stand in the 2027 presidential election
Neymar calls time on Brazil career after World Cup elimination
Brazil superstar Neymar indicated Sunday that his international career was over after the five-time World Cup winners went out of the tournament in the last 16 at the hands of Norway.That was his first international appearance since October 2023, but his only other appearance in the United States came Sunday against Norway. raa/mcd/as/rcw
Phillies legend Mike Schmidt talks about post-playing career health issues
Hall of Famer will throw out the first pitch at the All-Star Game in Philadelphia
Reds’ Hunter Greene gives up a career-high-tying 8 runs in 2026 debut
It was Greene's first start since his three-inning start in a loss to the Dodgers in Game 1 of the 2025 National League wild-card series.
Yankees news: Fried takes next step with live batting practice
Fried to throw batting practice today; four Yankees named All-Stars; Domínguez has biggest shot yet; June Swoon hits as Boone takes some heat; Caballero answers questions on career.
Yordan Alvarez blasts walk-off homer on July 4 for second time in career as Astros snap Rays' 9-game win streak
Just as he did in 2022, Alvarez brought the holiday fireworks, this time with a swing that capped a two-dinger, six-RBI performance.
MLB All-Star rosters announced, with Dodgers, Braves and Phillies tied for most players named
Vladimir Guerrero Jr. will start at first base despite having, so far, the worst season of his career.
Mariners vs. Blue Jays: Game preview and discussion
Logan Gilbert nears a career milestone as the Mariners try to find their offense
Tom Brady narrates epic sports video commemorating USA’s 250th birthday
Tom Brady’s legendary football career has been over for several years, but the seven-time Super Bowl champion continues to find new ways to remain in the spotlight. From becoming one of the biggest personalities in sports media to expanding his…
Random Ramsdom: They could use a ‘career backup’
Los Angeles Rams News and Links for 7/4/26
Former CIA official left Google to start AI business: Career advice
Candice Bryant spent nearly 16 years at the CIA before joining Google. She shares why she left Big Tech and the philosophy that's guided her career.
Notes From A Career In Private Equity: David Mussafer On Business
David Mussafer emphasized leadership, teamwork, continuous learning, disciplined investing, and AI adoption as keys to long-term business success.
Souhan: Reflecting on 36 years of scoops, spats and Minnesota sports history
My sports journalism career is coming to an end. I’ll miss a lot of people who may not miss me, but I will fondly remember the state’s biggest stars and other less-heralded ones.
Career coach shares résumé template she recommends for AI era
Amy Perrotta, the founder of a career branding company, says an effective résumé makes a recruiter "want to pick up the phone."
Aroldis Chapman breaks MLall-time strikeout record among relievers
The Red Sox closer broke a tie with Hoyt Wilhelm for the top of the career leaderboard.
Aroldis Chapman breaks MLB all-time strikeout record among relievers
The Red Sox closer broke a tie with Hoyt Wilhelm for the top of the career leaderboard.
UVM Health Network employees advance careers through Pathfinder Program
UVM Health Network employees are building their futures through the Pathfinder Program, a partnership with the Community College of Vermont.
Jimmy Butler believes he’ll return better than ever
Jimmy Butler is confident his comeback from ACL surgery will be a successful one. The Warriors star says he expects to return as one of the NBA’s top players while revealing his desire to finish his Hall of Fame-caliber career in Golden State.
UVM Health Network employees advance careers through Pathfinder Program
UVM Health Network employees are building their futures through the Pathfinder Program, a partnership with the Community College of Vermont
A career of flying for science (and the occasional sled dog)
Martin Stuefer, the director of the Hyperspectral Imaging Lab at the University of Alaska Fairbanks Geophysical Institute, is both a pilot and researcher.
Former NL MVP will continue his career, signs with Braves
The Atlanta Braves have made a veteran addition as they look to stay atop the National League playoff race, signing former National League MVP Andrew McCutchen to bolster their organizational outfield depth. McCutchen, who began the season with the Texas…
Clarksdale Native Ben Frazer
Young entrepreneur at the helm of Stovall Capital and Chinook Fire Protection It’s a long way from Clarksdale to Anchorage, Alaska, but Ben Frazer is moving forward with his business career there. That’s where he is the CEO of Chinook Fire Protection, which was acquired by his SEC-registered company, Stovall Capital. He is still […]
LeBron James' birthplace urges NBA star, 'Come home...please'
Akron's Summa Health, birthplace of LeBron James, posted a not-so-subtle message on Instagram urging the NBA star to finish his career in Cleveland.
Malik Willis Has 6 Career Starts and CBS Sports Just Ranked Him Among the NFL's Most Intriguing QBs
The NFL is a pass-heavy league, and teams rely on aerial attacks and high-scoring offenses not just to win games, but to contend for a Super Bowl championship. "After rejuvenating his career in Green Bay, Willis will get his first legitimate chance to be an NFL starting quarterback," DeArdo wrote. "It'll be a challenge, though, as Willis is joining a Dolphins team that is starting anew."
Rich Eisen belives he’s done doing play-by-play
Rich Eisen built a second career on NFL Network almost by accident, stepping into the play-by-play chair years after he’d already made his name as a host. It appears that part of his career is now over, as he told Sports Illustrated’s Jimmy Traina that he no longer expects to call games. “No, it is…
NFL QB rankings: Arizona Cardinals QB Jacoby Brissett near bottom
Even with career numbers last season, Jacoby Brissett is one of the lowest-ranked QBs in the league, per PFF.
Former Arkansas basketball players preparing for NBA Summer League
At the time of writing, eight players who finished their careers with the Arkansas men’s basketball team have been announced on Summer League rosters.
Croatia criticised for ‘unambitious’ changes to 2022 science law
Croatia’s science ministry has been accused of a lack of ambition, and even incompetence, over proposed changes to the country’s 2022 science law. Critics say an opportunity has been missed to fix wider shortcomings in the research and universities system.“This law, like all the previous ones, will not significantly change the current state of science in Croatia,” Vlatko Silobrčić, a member of the Croatian Academy of Sciences, told Science Business. “A small shift here and there will not have a significant impact.”The 2022 law introduced multi-year block grant financing of research, based on results, and changes intended to boost employment and career progression for researchers and lecturers. But implementation of the law has been uneven. “It became apparent that certain of its provisions were subject to different interpretations by higher education institutions and scientific institutes,” the science ministry said in its proposal for change. “This caused legal uncertainty in the system, administrative difficulties in implementation and, in certain cases, unequal treatment of teachers, scientists and students.”Most of the proposed amendments deal with technicalities in hiring and promoting staff, such as extending the committee deadlines from 60 to 90 days, or allowing applicants to cite all of their achievements and not only those since their last appointment.Both the ministry and Croatian media highlighted changes that would raise the retirement age from 65 to 67 years and allow part-time students 15 year rather than 10 years to finish their studies.The change to retirement age has been criticised for reinforcing a weakness in the system. According to Matko Marušić, professor emeritus at the University of Split, this will “allow unproductive teachers to advance and work longer, while hindering and discouraging productive ones.”A longtime campaigner for excellence-based meritocracy, he sees little hope in the new legislation. “I am not optimistic that things will improve,” he told Science Business. “As recent changes to the law in Croatia show, the legal framework is becoming increasingly hypocritical and harmful.”For Marušić, who analyses Croatia's university system in a recently published book, the situation is “unfavourable and constantly deteriorating” due to the criteria used for academic advancement.“The key criterion for advancement should be scientific productivity,” he said. “In Croatia [. . .] scientific criteria are increasingly lowered, and ineffective and absurd criteria such as waiting times for promotion and age limits for remaining in a job are promoted.” He would also like to see better criteria for the quality of teaching at universities. “In practice, teaching is not monitored or evaluated,” he said, estimating that up to a third of teaching simply does not take place. “Under the guise of university autonomy and bad laws, universities and faculties are allowed to earn additional money by increasing enrolment quotas that have nothing to do with the needs of the labour market.” Lack of ambitionDora Kršul, a reporter at Telegram.hr who covers science policy in Croatia, finds the rationale for changes “bizarre.” “The ministry responsible for supervising the uniform application of the law is changing the law because it is being implemented unevenly,” she said. “This primarily speaks to the power relationship in the sphere of science and higher education in Croatia, that is, the question arises as to who actually manages this system.”Rather than raising quality, she continued, the changes appear to be designed to help vocational and applied universities who have not been complying with the law.The Independent Union of Research and Higher Education Employees of Croatia said that the changes were “unambitious” and represent a missed opportunity for more important changes. “We think some of the changes are even negative,” it said in its statement on June 25. One of these is introduction of an “assistant” job title that allows people to be hired only for the duration of a project. Related articles: Elections to top science bodies test Croatia’s gender equality in researchSlovakia revises R&D approach to increase focus on competitivenessLatvia pilots citizen engagement in research grant evaluationsThe union’s president, Tvrtko Smital, who was part of the 15-member working group tasked with drafting the changes, told the local media there was a “worrying lack of ambition” in the process, and “lack of competence” in terms of research experience and understanding the problems in the system.“There is no clear will to deal with the problems,” said Smital, an assistant professor of marine and environmental sciences at the Ruđer Bošković Institute in Zagreb. “It’s a combination of unambitiousness and incompetence,” he went on, expressing his “deep frustration” with the situation. “There is no strategy, no clear thinking, and money is not being spent optimally.”Croatia’s science ministry has not responded to requests for comment.
Too Big? Jones Explains Poatan’s ‘Perfect Storm’
Jon Jones has a bit of experience with moving up to Heavyweight. “Bones” ruled the 205-pound roost for many, many years before finally making the leap in 2023. He teased a Heavyweight jump for much of that span, but Jones has always been a careful decision-maker in regards to his MMA career and (nearly) undefeated […]
Building connections across molecular life science
ASBMB President Ed Eisenstein reflects on how the society shaped his scientific career and outlines his vision for expanding connections across academia, industry and government to accelerate discovery, translation and community-building.
Cincinnati Reds middle infielder Matt McLain on playing centerfield
Cincinnati Reds 2B/SS Matt McLain made his first career MLB start in centerfield Wednesday night in Milwaukee.
Sports entertainment veteran homers with interactive gaming sports bar, baseball outing indoors
Serial entrepreneur Lance Windholz — who spiked a career in tech to build community around beach volleyball in Shawnee — is batting again; this time, taking a swing at sports entertainment and the resurgent popularity of baseball.
Students Explore Science And Research At Fourth Annual Discovery Day
Local students joined Cincinnati Children’s Discovery Day to explore research labs, meet scientists, and learn about careers in science and medicine.
Civalli strikes out 13, Nationals snap Red Sox's 5-game win streak with 8-1 rout
Cade Civalli gave up one hit in seven innings and had a career-high 13 strikeouts in the Washington Nationals' 8-1 victory over the Red Sox on Tuesday night, snapping Boston's five-game winning streak.
Pinellas County girls chart courses to marine science careers at USF summer camp
Since 1991, the University of South Florida College of Marine Science has hosted the Oceanography Camp — Especially for Girls. Every summer, 30 eighth-grade graduates have the chance to go on a research expedition and do what marine scientists do.
Seventeen's Joshua teases new work 'in music' and 'beyond'
Fresh off a UNESCO speech and Paris fashion week, Seventeen's Joshua Hong gave Business Insider a hint of what's to come for his career.
Cam Schlittler's odyssey: Tigers ambush Yankees' starting pitcher
New York's starter yielded three homers in the same inning Tuesday for the first time in his two-year career.
What 124 Future Business Leaders Really Think About AI and Work
Insights from 124 career assessments written by UMD-Smith graduate students show 98% expect artificial intelligence to transform, not eliminate, their careers. The analysis also found AI raises performance expectations while increasing demand for strategic thinking, AI literacy, ethical judgment and critical evaluation of AI-generated work.
Trump nominates acting Labor Secretary Keith Sonderling to permanent role
President Donald Trump nominated acting Labor Secretary Keith Sonderling to keep the role permanently. Trump made the announcement on Truth Social, touting his experience during his first and second terms in the Labor Department. “Throughout his career, Keith has proven his dedication to delivering strong results for the Hardworking People of our Country, and I […]
Running with purpose: SAU alumni build a business and a ministry one race at a time | News
For Briston and Carley Rains, running is more than a sport. It is a career, a calling, and a ministry. The two Southern Arkansas University graduates are the owners of Texas Outlaw Running…
9 former child stars who found success outside Hollywood
These former child stars found impressive careers outside the spotlight. See which of your favorites became lawyers, teachers, veterinarians, CEOs, and more.
Warriors backup point guard declines 2026-27 player option
De'Anthony Melton has declined his player option for next season after averaging a career high in points last year.
Atlanta Hawks celebrate graduating third cohort of women business leaders
The Georgia woman’s leadership empowerment program, which is celebrating the completion of its third cohort, brings in early-career women from typically male-dominated industries in Atlanta for mentorship and professional development.
Connie Cepko: A Life in Science Mapping the Retina — and Working to Save It
Over a five-decade career, HHMI Investigator Connie Cepko has reshaped our understanding of how the retina develops and forged new paths toward treating blindness and inherited retinal disease. This story is part of a series exploring the careers of HHMI scientists.
Taylor Swift's video tribute to Alan Jackson divides crowd at country legend's final show
Viral TikTok footage captures what appears to be a mix of cheers and boos after Taylor Swift's pre-recorded video tribute to Alan Jackson's career.
What really happened to Lizzo’s career?
The pop star is back with a new album, a new look and a lot of baggage. People aren’t buying it.
Nhouyvanisvong, Green Among Attendees at NCAA Career in Sports Forum
Macalester College rising senior Adi Nhouyvanisvong (Wayata, Minn./Minnetonka) of the women's soccer team and rising junior Jay Green (Roseville, Minn./Mounds Park Academy) attended the NCAA's Career in Sports Forum, held May 27-30 at the NCAA headquarters in Indianapolis, Ind.
Careers That Shaped Biology
Every great scientific career begins with a question no one has been able to answer — and a scientist stubborn enough to keep asking it. This series looks back at the careers of some of HHMI’s most distinguished scientists — people whose contributions have changed what we know about life itself, and whose stories reflect the best of what science, and scientists, can be.
Nancy Pelosi to establish new democracy institute at UC-Berkeley
The former House speaker is preparing to leave Congress after a nearly four-decade decorated career.
At 99, this Pasadena ballet teacher has no plans to stop dancing
Helga Monson de Kansky was once predicted to become ballet's next star. Instead, she chose a life with her family and a career as a dance instructor.
Queerying neuroscience: How legislation and institutions reframe LGBTQIA+ researchers’ careers
In honor of Pride Month, The Transmitter spoke with three researchers who surveyed hundreds of LGBTQIA+ neuroscientists to better understand how institutional support, harassment and policy intersect to shape their professional trajectories.
We turned 80-year-olds into trained health monitors to save lives and boost senior dignity
As a career geriatrician, I’ve long known that some of society’s finest minds are being underappreciated while living in senior communities. So I helped to develop a new health program to help put older adults on the watch as health monitors.
Prevalence and severity of mental health problems in early-career researchers: a systematic review and meta-analysis
Nature Human Behaviour - Mental health concerns among early-career researchers are increasingly gaining attention. This preregistered systematic review and multilevel meta-analysis quantifies...
Serena Williams 'Hates' The New Rules Surrounding Tennis
A lot has changed in tennis over the course of Serena Williams' career. Williams, now 44 years old, will make her return this week. She'll play in Wimbledon, which starts on Monday. Williams' first round match is set for Centre Court at 11:20 a.m. E.T. on Tuesday. But as Williams is set to return ...
Important Penn State prospect makes notable physical transformation
Penn State star Max Granville’s career has been stunted by injuries so far, but his body transformation is sure to excite fans.
Miami Heat’s Sign-and-Trade Package for LeBron James Revealed
The Miami Heat may explore LeBron James’ free agency situation this offseason in any chance of bringing the veteran superstar back to the franchise.James is nearing the end of his storied career, and after exercising his player option with the Los Angeles Lakers, he is eligible to become an unrestricted free agent. Various speculations are […] The post Miami Heat’s Sign-and-Trade Package for LeBron James Revealed appeared first on HEAVY.
Career coach recommends 4-hour burnout-proof job application routine
A career coach advises job seekers against spending all day applying to jobs. She says a four-hour routine is burnout-proof and more effective.
Inside country legend Alan Jackson's triumphant finale concert
Country music legend Alan Jackson has ended his touring career | KMBZ
Inside country legend Alan Jackson\'s triumphant finale concert
Country music legend Alan Jackson has ended his touring career. On Saturday night, he performed his final show at Nashville's Nissan Stadium. The event, titled “Last Call: One More for
Inside country legend Alan Jackson's triumphant finale concert
Country music legend Alan Jackson has ended his touring career | WWL
Inside country legend Alan Jackson's triumphant finale concert
Country music legend Alan Jackson has ended his touring career.
Lionel Messi becomes first man to score in 7 straight World Cup games with free kick goal in win over Jordan
Messi now has 19 career World Cup goals.
Gunnar gives back: O's shortstop surprises local kid with specialized cleats
BALTIMORE -- The story of 11-year-old Declan Lefevre’s youth baseball career is inspirational. When Declan was about 4 years old, a doctor noticed his legs were different lengths. And it wasn’t something he would grow out of, either, which is something his parents -- father Jeff Lefevre and mother Nichole
Women Over 50 Aren't Just Starting Businesses. They're Redefining Work.
Women over 50 are starting businesses, but the bigger story is how they're redefining work through greater flexibility, purpose, and control over their careers.
Could Israel’s coming election see an end to Netanyahu’s political career?
Israel's Prime Minister Benjamin Netanyahu faces mounting political, legal and US pressure ahead of crucial elections.
An Unexpected Vocation: Jaibir Nihal Singh’s Journey from Film Student to Business Executive
Though trained as a filmmaker at Pepperdine University’s Seaver College, Jaibir Nihal Singh found a way to leverage his creative skills into a career as a successful innovator. Now, as a member of Forbes 30 under 30, Singh credits his education as the launchpad for his vocation, even if he never saw it coming.
Summer Science Program
Explore information about the Summer Science Program at Arkansas Children's Hospital, a career readiness program for college students, including eligibility and how to apply.
Master Inventor Hoffman Turns Chemistry Into Capability | Johns Hopkins University Applied Physics Laboratory
Christopher Hoffman has been recognized as a Johns Hopkins APL Master Inventor, a distinction earned through a career spent asking a simple question: What can chemistry can do to solve a real-world problem?
New York Jets News: Geno Smith Needs Another Career Comeback
Your daily links to the New York Jets
How Perizaad Zorabian Left Bollywood And Turned Her Family's Poultry Business Into A Rs 120 Crore Enterprise
Perizaad Zorabian was at the peak of her career when she decided to quit acting and turned her focus to her family's poultry business
CRAWFORD | Kenny Klein, beloved longtime Louisville sports information director, dies at 66
Klein's career spanned nearly four decades and helped shape the public face of Cardinals athletics through some of its greatest triumphs and most difficult crises.
Baxter Health Heart and Vascular Clinic Welcomes Brandi Watson, APRN
Baxter Health is proud to welcome Brandi Watson, APRN, to the Baxter Health Heart and Vascular Clinic. Watson joined the team on May 15 and is currently accepting new patients. Watson brings more than 25 years of experience caring for some of the most critically ill patients. Much of her career has been spent in intensive care settings, where she learned to make fast, high-stakes decisions for patients whose lives depended on getting the right care at the right moment. That kind of experience, which is gained through years at the bedside, is exactly what heart and vascular patients need from a provider.
Making Our Own Luck
We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.
CT AHEC Introduces New Public Health Programs and Partnerships
New public health and public health careers enrichment programs for high school and emergency medical technician (EMT) and paramedic college students launch ...
Myles Garrett's Rise Could Fuel T.J. Watt's Next Steelers Surge
For years, T.J. Watt and Myles Garrett have been linked in one of the NFL's defining player rivalries. Now, with Garrett pulling ahead in recent seasons and Patrick Graham arriving in Pittsburgh, Watt has fresh reasons to respond. For much of their careers, Watt's production far outpaced Garrett's. That changed in 2023 when the Cleveland Browns hired Jim Schwartz as defensive coordinator and Garrett elevated his game to another level.
Former New Orleans Saints receiver Joe Horn ready for induction into Louisiana Sports Hall of Fame
"All the accolades that come behind my career and my work, I'm very humbled by it all"
David P. O'Brien
About five years ago, David P. O'Brien had a comfortable position at Marsh & McLennan Cos., where he held the top post at the financial giant's Louisville, Ky., office. Despite the lofty rank, Mr. O'Brien found himself longing to be at a smaller company that had to work a little harder to land business. That desire led him away from Kentucky five years ago and to Cleveland, where he serves as executive vice president at business insurance agency Oswald Cos. "I left Marsh before it was en vogue," he said, referring to layoffs and defections at Marsh over the course of this year that followed accusations of bid rigging at the big firm. Above all, Mr. O'Brien, 38, wanted to work at a company that relied on its inventiveness, rather than its name, for business. He said he has found that at Oswald. "It causes you to be more creative, to be more resourceful," Mr. O'Brien said. For instance, an Oswald client seeking to do business internationally might be directed to the network of offices abroad run by competitors such as Marsh and Aon Risk Services Inc. "We're going to use whatever access into the market that makes the most sense for our clients," he said. Of course, using such a strategy can be dangerous for Oswald if its client decides to further a business relationship with one of the firms Oswald recommended. "That's the obvious question and why it's nontraditional," he said. "I think if we're good, and if we're bringing value to the client, then there's no risk. I'm not threatened by it." Imaginative business solutions of that type made his career move to Oswald from Marsh worthwhile. "It's very much a challenge," he said. "It helps you keep your edge. I'm all for the competition." John Jacunski, currently vice president and corporate controller at York, Pa., paper company PH Gladfelter Co., met Mr. O'Brien four years ago when Mr. Jacunski was at WCI Steel Inc. in Warren. So impressed was he with Mr. O'Brien's work for WCI that Mr. Jacunski has retained the Oswald executive at PH Gladfelter. "He's a young guy for the position he has, but he's done a great job for us," Mr. Jacunski said. Among his roles at Oswald, Mr. O'Brien leads the firm's client retention efforts and also serves as director of its property and casualty group. "You don't have the same human resources," he said of the job jump to Oswald. "You don't have, obviously, the safety net a big company has." But sometimes, it can be difficult to ascertain individual contributions when working at a big company. "I wanted to be able to see the end results of my work and my efforts," Mr. O'Brien said.
Keiser's Paul Dodson Voted 2025-26 SUN Sports Information Director of the Year
The Sun Conference is pleased to announce that Keiser University Assistant Athletics Director of Communications Paul Dodson has been named the 2025-26 Sun Conference Sports Information Director of the Year, as voted on by his peers across the league. The honor marks the third conference SID of the Year award of Dodson's career after previously earning the distinction in 2022-23 at Keiser University and 2018-19 while at Johnson & Wales University.
Women in Science: Dr Jennifer D’Souza - TIB-Blog
The blog series “Women in Science” introduces women from TIB who share insights into their careers and personal experiences in science. Dr Jennifer D’Souza studied Natural Language Processing at the University of Texas at Dallas, USA, and is now an AI/NLP research group lead at TIB. In this interview, she shares what she finds most rewarding about a career in science, the lessons she has learned along the way, and her hopes for the next generation of women scientists.
Mookie Betts continues resurgent streak with 300th career homer in Dodgers win
Travis Kelce's Journey: From Rookie to NFL Superstar and His Life with Taylor Swift
Travis Kelce is entering his 14th season in the NFL, all of which have been with the Kansas City Chiefs. After being selected No. 63 overall in the third round of the 2013 NFL Draft by Kansas City, Kelce played only a single special teams snap as a rookie, in a Week 2 game against the Dallas Cowboys. The seven-time All-Pro has set all-time marks for the Chiefs, such as surpassing Hall of Fame tight end Tony Gonzalez's 10,940 career receiving yards (13,002) and passing three-time first-team All-Pro Priest Holmes' 83 total career touchdowns (85).
What Arkansas basketball’s Trevon Brazile brings to Denver Nuggets
Trevon Brazile is headed to Denver. After a long career with Arkansas basketball, Brazile was selected by the Nuggets in the second round of the NBA Draft.
Where health begins
Dean Bernadette Boden-Albala has spent her career exploring the factors that affect well-being long before disease develops
Take 5: Career Advice from the Sports World
Kellogg faculty share lessons on how to get ahead in fiercely competitive fields.
Program Director Shares How Articulation Agreements Benefit Meredith Pre-health Post-Baccalaureate Students
Karthik Aghoram, director of Meredith’s Pre-health Post-Baccalaureate Program, recently spoke with Inspira Advantage about the program’s articulation agreements and why they are valuable for students seeking careers in health care.
Behind the scenes of a successful entertainment career with Jenny Austin ’12
From interviews with big-name celebrities like Will Ferrell to assisting with casting for hit television shows like “The Summer I Turned Pretty,” Jenny Austin ’12 is living out her dreams....
Young children losing health coverage faster than older kids — but still faring better in California
The latest education news updates from EdSource.