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Sports star meet-and-greets headline Dad’s Day Block Party
Visitors participated in mini golf, photo booth activities and superhero-themed cape and mask stations.
Helene-hit Swannanoa businesses say state rules block access to federal recovery funds
Swannanoa business owners who lost everything after Helene are speaking out about not being able to apply for federal disaster recovery funds.
Iowa Supreme Court blocks University of Iowa from repurposing Black science scholarship
A scholarship created to help Black students pursue careers in chemistry and the physical sciences is at the center of a new Iowa Supreme Court decision that bl
Will Mike Evans Regret Leaving Buccaneers for 49ers?
A franchise icon departs Tampa Bay chasing a second ring, but a blockbuster trade by a division rival threatens to derail Mike Evans' championship plans in San Francisco.
Bills, Vikings Connected in Massive $140M Trade Rumor
A proposal has been made from one prominent NFL Analyst, who predicted a blockbuster Justin Jefferson trade rumor connecting the Bills, Vikings.
Senate blocks extending key surveillance program following backlash over Trump pick to lead intel
Some Republicans joined Democrats in the 47-52 vote against a procedural motion that would have set up a final vote on the extension next week, complicating efforts to extend the critical program before it expires on June 12.
This viral NYC World Cup festival brings Africa’s biggest stars to Brooklyn
As New York prepares for one of the busiest weekends of the summer with FIFA World Cup festivities set to draw visitors from around the globe, a
US rate futures raise rate hike odds in December after jobs data
U.S. interest rate futures on Friday increased the chances that the Federal Reserves will raise interest rates by the December policy meeting after a blockbuster payrolls number for May, which sharply exceeded market expectations.
Senate blocks extending surveillance program following backlash over intel pick
Six Republicans joined nearly all Democrats in opposing the measure, which would have set up a final vote next week
Popular Blood Pressure Meds Linked To Kidney Damage Risk In Type 2 Diabetes
By Dennis Thompson HealthDay ReporterFRIDAY, June 5, 2026 (HealthDay News) — A common class of blood pressure medications might contribute to kidney damage among people with type 2 diabetes, a new study says. Dihydropyridine calcium-channel blockers (DCCBs) work by relaxing blood vessels, and are ...
Wall St Week Ahead Blockbuster SpaceX IPO set to test high-flying US stocks rally
The long-awaited, massive SpaceX initial public offering is expected next week, a major event for the U.S. stock market, with investors wary of possible overexuberance after a stunning rally.
Barcelona battling Atletico Madrid for three blockbuster signings this summer
Barcelona and Atletico Madrid appear to be heading towards one of the most intriguing transfer battles of the summer, with both clubs targeting several of the same high-profile players ahead of the ne...
Rams Land Myles Garrett: Should the Lions Make a Move?
After the Rams landed Myles Garrett, the question shifts to Detroit: Should the Lions make a blockbuster move of their own, or trust the roster they've built?
Seattle-founded firm ditching its namesake downtown office tower
Docusign is signaling a plan to leave the Docusign Tower for a new office a few blocks away.
Four Senate Republicans again unite with Dems to block Trump's SAVE America Act
Four Senate Republicans joined Democrats to kill the SAVE Act voter ID amendment for a second time, blocking it from the budget reconciliation package.
Food, entertainment, games | Taste of Lititz returns on Friday
Taste of Lititz will return to East Main Street in Lititz, Lancaster County, Friday evening, offering food, entertainment, and games in a block party-style event.
Filtr is a new privacy tool that blocks ads in almost every iPhone and Mac app
This popular ad blocker app for iPhones, iPads, and Macs can now block ads from loading inside apps, including web browsers, thanks to a new feature in the latest Apple software.
Court blocks mental health diversion for suspect in Santa Monica hate-fueled pipe attacks
A man accused of carrying out a series of racially motivated attacks in Santa Monica, including an attempted murder, will face trial after the California Supreme Court declined to review a ruling o…
Digging out: One man’s recovery and the business it inspired
Craig Stevens was just a kid when he started to build worlds. While growing up in West Brookfield, he’d take the blocks he was always given for Christmas and construct cities in his backyard. He used the garden hose to make flowing rivers, his hands to sculpt the land. When he was 10, he wanted […]
Sporticast: Stephen Curry Takes His Longest-Distance Shot Yet
On the 558th Sporticast episode, hosts Scott Soshnick and Eben Novy-Williams discuss some of the biggest sports business stories of the week, including a blockbuster sneaker deal. Golden State Warriors star Stephen Curry announced a 10-year agreement with Chinese brand Li-Ning earlier this week. Curry was a sneaker free agent for less than a year, …
Shokz upgraded its open earbuds with better sound and a lighter design
Upgraded earbuds that don’t completely block the world around you.
Prologis CEO: We built our business around the economy
Prologis CEO Dan Letter joins 'Mad Money' host Jim Cramer to talk its data center business build out.
In a first, House votes to block Trump from ordering further strikes on Iran
The Senate advanced a similar war powers resolution last month on a procedural vote, reflecting growing impatience with a conflict Congress hasn’t authorized.
SpaceX sets the stage for a record $75 billion IPO
Elon Musk’s SpaceX unveiled plans Wednesday to set a $135 share price in its initial public offering price, for a sale worth $75 billion. The blockbuster debut would make Musk – already the world’s richest person – the first-ever trillionaire.
Americans Opposing AI Will Become America’s ‘Biggest Political Crisis,’ Top Investor Says
The former U.S. energy advisor warned the industry must change how it talks to the public or risk being blocked from building data centers and power plants fueling AI.
Sean McVay breaks his silence on Aaron Donald returning
The Los Angeles Rams made a blockbuster trade with the Cleveland Browns to acquire the reigning Defensive Player of the Year in the NFL, Myles Garrett, who is coming off an NFL record-setting 23-sack season. Since acquiring the NFL’s single-season sack record holder, there has been more and more buzz surrounding a potential return of…
A rare Trump setback, a missing congressman and Spencer Pratt: 6 takeaways from the latest midterm primaries
The contours of a premier Senate race took shape in Iowa, while President Donald Trump’s endorsement streak ran into a roadblock there.
May's top PlayStation games by copies sold
Yesterday’s State of Play gave us an idea of where PlayStation’s heading next. But we’ve had our May estimates for a couple of days now (we always update our data daily for clients), so it’s time to look at what performed best on PlayStation last month. We’ve got a new IP at the top, two evergreens doing their evergreen thing, FC26 smashing it ahead of the World Cup Plus pivot, and a quiet but promising result for Lego Batman. Let’s have a look at the state of Play…Station’s top games for May. 007 takes #001 007 First Light sold 1M copies on PS5 in May, easily making it the month’s top PS5 game by copies sold. Over 80% of those May copies were digital, which is broadly in line with where PlayStation’s digital share has settled for new releases this year. To date, 007 First Light has sold through 2.2M copies across platforms (so no unsold retail copies in that figure). The platform split is 55.1% PS5, 33.1% Steam, and 11.8% Xbox (console, Windows, and cloud combined). In gross revenue terms, 007 First Light has generated $150M. Owing to regional pricing and audience composition differences, the consoles make up a higher share of revenue than they do copies. Of the $150M, 60.5% came via PlayStation, 27.6% via Steam, and 12.9% via Xbox. Part of this is because over two-thirds of 007 First Light‘s PlayStation audience is in North America (43.4%) or Western Europe (23.2%), where local currency means the game generates more revenue per player. On Steam, under half of First Light‘s audience is from those same regions (31.8% North America, 15.1% Western Europe). As we covered in last week’s 007 Steam piece, the Steam version is pulling in higher-than-expected numbers in China, which now accounts for 17.3% of First Light‘s Steam audience. 007 is the equivalent of $44 USD in China, which is roughly 37% cheaper than the US price and about 44% cheaper than Western Europe. Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe The crossover data backs up what we’ve seen all year about launch-window cohorts. 11% of PS5 players who played 007 First Light in May also played Lego Batman: Legacy of the Dark Knight, which launched just a few days before. Last month was a great month for Denmark! IO Interactive is Copenhagen-based, and Lego Group is headquartered in Billund (TT Games is UK-based but produces work under Lego Group licence and direction). Speaking of which… A very blocky #2 and #3 Minecraft sold another 788K copies on PlayStation consoles last month. Business as usual, since Minecraft hasn’t sold fewer than 760K copies in a single month all year. With over 350M copies sold across all platforms, Minecraft is the best-selling game in history and one of the strongest brands in the world. Every month, a new cohort of children reaches Minecraft age, which guarantees a constant volume of new sales regardless of what the broader market is up to. The demographic refresh rate is truly impressive, with the audience renewing itself faster than it’s churning. Lego Batman: Legacy of the Dark Knight shifted 757K copies on PS5 last month, bringing its lifetime total on the platform to over 800K. Across all platforms, Legacy of the Dark Knight has now passed 1.5M sold through, so PlayStation accounts for over half of the game’s players. The May crossover data for Legacy of the Dark Knight on PS5 is also useful. 27% of those players also played Fortnite, 16% Roblox, 16% FC 26, and 14% NBA 2K. That’s the household-and-family cohort showing up, plus the launch-window cohort of core gamers who buy practically everything. FC 26 gets players through the door ahead of the World Cup FC 26 sold 411K copies on PlayStation last month (90% via PS5), the fewest copies FC 26 has sold all year and down heavily from April’s 700K. Part of this dropoff is because FC 26 has been available as a PlayStation Plus monthly game since 6 May, cannibalising premium sales. Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe The strategic logic is straightforward for EA, which is sacrificing premium unit sales in May to build up the player base ahead of the FIFA World Cup, which kicks off on 11 June. Obviously, a bigger player pool going into the tournament means a bigger pool of potential Ultimate Team spenders during the period when football attention is at its peak. The early returns are around what you’d expect, with 4.4M new players accessing FC 26 via PS Plus last month – a substantial new spender pool. Anecdotally, a few of my mates who were ‘’skipping FIFA and Ultimate Team this year’’, were drawn back in via PS Plus. Lo and behold, one of them is buying packs like it’s going out of fashion. Whether this is all a smart trade for EA depends entirely on the Ultimate Team conversion rate over the next six weeks. Either way, the short-term engagement impact on the game as a whole is evident. FC 26‘s MAUs hit a record 24M on PlayStation in May, up 30% from the previous record set in April. GTA V does what GTA V always does Rounding out the top five is another evergreen title. Grand Theft Auto V shifted another 387K copies on PlayStation last month. No matter what else is happening in the industry, GTA V keeps pulling players in. It’s sold another 1.8M copies on PS5 in the first half of this year alone, helping the franchise pass the 230M-sold milestone across all platforms. Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe I have a theory that Minecraft and GTA V are doing the same thing at different demographic levels. Both are functioning as generational gateway games that the audience ages into faster than it ages out of. Minecraft captures kids around age 6-10, GTA V captures much of the same audience around age 12-15 (unofficially, of course). The crossover data suggests this: 40% of GTA V‘s monthly PlayStation players typically play Fortnite in any given month, while 30% play Roblox. Household accounts aside, that’s not the original GTA V audience from 2013. Of course, the under-12 audience would love to get their hands on GTA, too. It’s always been the way of things, and some parents are happy to oblige. Mine did too back in the day, and I turned out just fine. Right? Right!? Want to get your hands on our data for yourself – for free? We’re offering a free trial of our platform for games companies. Send us a message here, or reply to this email, and we’ll set you up. The last word Reply to this email – or reach out here – if you have any feedback for the newsletter – or want to request a game for us to cover. [Alinea Analytics boasts the most accurate PC and console estimates in the business. Game makers use our platform to understand their audience, keep an eye on the competition, monitor sales trends, and spot new opportunities. We equip game studios and financial institutions with accurate data and the confidence to make smarter, data-driven decisions. Want to talk about all things games market data? We’d love to chat!]
Milwaukee shouldn’t trade Giannis Antetokounmpo for one major reason
With constant trade talks swirling around superstar Giannis Antetokounmpo, this could be the summer a blockbuster deal finally happens. The Bucks’ owner has made comments about wanting to make a move before the NBA Draft to acquire assets, and looking…
Illinois hospitals urge Pritzker to quickly sign bill before Eli Lilly cuts off drug discounts
Illinois’ hospital association contends the move by Eli, which has also been threatened by the other large, global GLP-1 manufacturer, Novo Nordisk, is simply an unnecessary roadblock.
Franklin Templeton says Wall Street fears blockchain because it threatens its profits
Jenny Johnson, Franklin Templeton's CEO, said blockchain and crypto threaten a huge number of business models that exist today in traditional finance.
Polis protects system rigged against workers
By Jeremy Ross Shame on Gov. Jared Polis. He used his veto pen again to indulge the billionaire corporate elite by denying the freedom of workers to join together and form a union without being threatened, fired or blocked by a second election. For two years in a row, the Worker Protection Act passed out […]
French UFC fighter Gane blocking out politics before White House bout
French mixed martial artist Ciryl Gane said he is blocking out the political noise ahead of his unprecedented fight at the White House in Washington.But he admits it will be a unique experience, as it was when he visited the White House a few weeks ago.
Google must give UK publishers choice to block AI search summaries, says competition watchdog
Rolling coverage of the latest economic and financial news
Supreme Court allows Alabama to use congressional map favoring Republicans in this year's elections
The Supreme Court is allowing Alabama to use a congressional map favoring Republicans in this year’s elections, blocking a lower court ruling that the map intentionally discriminates against Black people
A Look At AMC Entertainment Holdings (AMC) Valuation As May Attendance Hits Highest Level Since 2019
AMC Entertainment Holdings (AMC) is back in focus after reporting its highest May attendance since 2019, with 25.5 million guests, along with a stock rally tied to recent blockbuster releases and revenue diversification efforts. See our latest analysis for AMC Entertainment Holdings. Recent box office wins and revenue experiments have coincided with a sharp 90 day share price return of 75.42% and a 30 day share price return of 42.76%, although the 1 year total shareholder return is still down...
Recent mock draft links Rockets to shot-blocking machine
A recent mock draft completed by Jonathan Wasserman has the Houston Rockets selecting Ugonna Onyenso with the No. 39 overall pick.
NJ sues Newark migrant jail owners over blocked health inspections
State officials are demanding that health inspectors be given full access to the jail they say they have been unlawfully barred from entering.
NJ Sues Delaney Hall Operator After It Refuses Full Access to Health Inspectors
Davenport, Department of Health File Complaint Against GEO Group After Inspectors Are Blocked From Conducting a Full Inspection.
White House Seeks to Impose Political Test on Billions in Federal Grants
A new proposal would allow the administration to block grants if they do not satisfy President Trump’s agenda or support what it calls “anti-American” values.
Grading the Myles Garrett, A.J. Brown blockbuster NFL trades; Stanley Cup Final preview
Plus Serena Williams returns and Odell Beckham Jr. is back with Giants
CVS continues to celebrate soccer with community events
CVS celebrates soccer this summer with local block parties, fan experiences and FIFA merchandise, bringing communities together nationwide.
Trump administration says it will comply with court order to pause $1.8 billion compensation fund
The Trump administration says it will comply with a court ruling temporarily blocking a nearly $1.8 billion fund meant to compensate allies of President Donald Trump
Browns trade Myles Garrett to Rams in blockbuster deal that includes 2024 DROY Jared Verse
Browns reportedly trading Myles Garrett to Rams in blockbuster deal that includes 2024 DROY Jared Verse
Business News June 2026
• The Cornell School celebrates 10th anniversary! • “School’s Out for Summer “ market at Bethany Village • Cedar Mill Farmers Market • End of School Block Party • Speech & Debate summer camp • BodElite Introduces Emsella for pelvic health • Buying a Home? What to Know Before You Remodel • How CWS sets rates for your community • Sunset Credit Union news • New Bottle Drop at Target store
3 Takeaways From Rams' Blockbuster Trade For Myles Garrett
The Los Angeles Rams continue their chase for another Super Bowl with a massive trade for Myles Garrett.
Myles Garrett traded from Browns to Rams as Los Angeles goes all in for Super Bowl run
Los Angeles is loading up for a Super Bowl run by acquiring the reigning Defensive Player of the Year in a historic blockbuster trade.
In a victory for science advocates, a federal court blocks the Trump administration's push to dismantle NCAR
The decision will delay attempts to break up a center often called the “mothership” of climate science
World’s First 8.1L Big Block C8 Corvette Finally Hits the Freeway
Three and a half years of engineering have brought this beast to life with direct injection, variable valve timing, and way more.
AMC Stock Pops as Blockbuster Sequels and Horror Hits Drive Big Attendance Numbers
AMC Entertainment stock soars after the movie theater operator announced 25.5 million people attended the theater last month, the strongest May attendance since before the Covid-19 pandemic.
Hasan Piker and Cenk Uygur blocked from entering UK by Home Office
The US citizens and left-wing content creators with huge online followings were due to speak at the SXSW London festival and Oxford this week.
Streets closed due to business fire
Bimbo Bakeries is located in the 1300 block of Adams Avenue.
“I understand” – Rodri issues fresh update on Manchester City future
Rodri has stated he will block out all contract and transfer distractions until the conclusion of the upcoming FIFA World Cup in North America.Following Pep Guardiola’s departure, elite suitors – ...
DHS wants to block airlines from sanctuary cities. Experts say it would be chaos.
Homeland Security Secretary Markwayne Mullin has a plan to punish cities that don’t enforce federal immigration policies
Enhabit’s new CEO sees ‘opportunity’ in federal home health, hospice moratorium
Dale Clift took the reins of Enhabit at a somewhat precarious time for the home health and hospice fields — just as a six-month moratorium on Medicare home health and hospice agencies took effect. But the seasoned home health owner doesn’t see the moratorium as an impediment to growth. It’s more of a roadblock to navigate around, he said.
Could Dejounte Murray Be Houston’s Next Point Guard?
Forget the flashy blockbusters. This former All-Star offers the steady playmaking and scoring punch Houston requires to stabilize their backcourt while navigating a high-stakes offseason pivot.
Sabalenka, Osaka clash in blockbuster French Open tie
Four-time Grand Slam champions Aryna Sabalenka and Naomi Osaka will go head-to-head in the first French Open women's night match in three years on Monday, as a host of men's players eye a maiden major quarter-final.Osaka struggled initially for form after rejoining the tour, but reached the US Open semi-finals last year, the first time she had made the second week of a Grand Slam event since winning her second Australian Open title in 2021.
Liverpool take massive step closer to blockbuster Yan Diomande agreement
Liverpool are moving closer to a blockbuster agreement for RB Leipzig star Yan Diomande.Liverpool have some major moves to make. In fact, they’ve just added a need for another one - in the dugout.Ar...
Community Health launches Executive Physical program
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FULL SHOW: Inside INdiana Business 5/31/26
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Pulling Customs From ‘Sanctuary’ City Airports Would Cause Chaos, Business Groups Say
Homeland Security Secretary Markwayne Mullin’s proposal could block hubs like Boston, New York and Los Angeles from accepting international flights.
Victor Wembanyama's backup Luke Kornet jokingly accepts LeBron James comparison after chasedown block in Game 7
Trump vents about judge who blocked the Kennedy Center renovation and fumes over his legal setbacks
President Donald Trump is fuming about a court ruling that blocked his renovation plans for the Kennedy Center in Washington.
Backrooms is a certified blockbuster with a $38 million opening day
It’s already the biggest opening weekend for an A24 movie ever.
Elected leaders and advocates launch new car-free parks campaign
A block party focusing on car-free parks will feature children’s art activities, ping-pong and a bike wash.
Cowboys Headlines: Cowboys 2026 roadblock, Prescott's biggest obstacle
Here are the latest news and note about the Cowboys and teams around the NFL.
Chinese scientists create ‘kill-them-all’ algorithm for drone warfare
Smart web identifies objects as friend, foe or terrain, meaning drone swarms can hunt even when communication is jammed and vision blocked.
New 3D silicon chip breakthrough could extend Moore’s Law for years
As traditional chip miniaturization slows, researchers have found a way to pack more computing power into the same space by stacking silicon circuits in multiple layers. The new process uses ultra-thin silicon membranes and low-temperature manufacturing techniques to overcome a major obstacle that has long blocked the production of true 3D chips.
New 3D silicon chip breakthrough could extend Moore’s Law for years
As traditional chip miniaturization slows, researchers have found a way to pack more computing power into the same space by stacking silicon circuits in multiple layers. The new process uses ultra-thin silicon membranes and low-temperature manufacturing techniques to overcome a major obstacle that has long blocked the production of true 3D chips.
Judge says Kennedy Center board violated law putting Trump's name on building, blocks closure
A federal judge ruled Friday that President Donald Trump's name was illegally added to the Kennedy Center and blocked the administration from closing the cultural and arts venue for major renovations.
Kraken co-CEO on the business amid the company's upcoming IPO
Arjun Sethi, Kraken co-CEO, joins 'Power Lunch' to discuss the state of the crypto sector, how AI impacts the blockchain and much more.
Legion Sports Fest returns to Reno more action packed than ever
More than 2,000 athletes from 10 sports will compete across the Reno Ballroom, Reno Events Center, and outdoor blocks.
Judge says Trump can’t add his name to Kennedy Center and blocks planned closure
A federal judge on Friday blocked the Kennedy Center from temporarily closing its doors for a yearslong renovation and said its board violated the law when it added President Donald Trump’s name to the historic performing arts venue.
Why a federal judge is blocking Trump’s ‘anti-weaponization fund’ (for now)
Kenyan court temporarily blocks U.S. plan for Ebola quarantine facility
The U.S. had set up the facility in Kenya to take in Americans exposed to Ebola, with a plan to send patients who develop symptoms to European countries for care.
Judge temporarily blocks payouts from Trump's $1.8B 'anti-weaponization' settlement fund
A federal judge has temporarily blocked President Donald Trump’s administration from paying any claims through a new $1.776 billion settlement fund for the Republican president's allies who believe they were victims of a weaponized government.
Judge temporarily blocks payouts from Trump's $1.8B 'anti-weaponization' fund
Judge Leonie Brinkema also barred the government from moving forward with the fund's creation while litigation is pending to challenge it
Exynos 2600’s Heat Pass Block Performs Better Than A Liquid-Nitrogen-Cooled Snapdragon 8 Elite Gen 5, Enabling Practical Uses For Future SoCs
A test shows that Samsung’s Heat Pass Block technology is a much more practical way of cooling an Exynos 2600
The Witcher 4 is the work of over twice as many CD Projekt staff as The Witcher 3, in a fresh display of how blockbluster team sizes have ballooned
The Witcher 4 is the work of over twice as many CD Projekt developers as The Witcher 3: Wild Hunt, the company's execut…
Giants’ Rafael Devers Makes Agency Change After Trade Report
The San Francisco Giants slugger has more than $225 million remaining on a blockbuster contract signed with the Boston Red Sox.
Dell stock explodes higher after blockbuster AI-fueled earnings
Dell is among a handful of 2000s-era computer companies that have gotten a major boost from AI. The company crushed analysts' earnings estimates.
San Antonio Spurs star “Wemby” is rocking the NBA playoffs. Science can help explain why
Wemby’s height gives him an advantage in blocking and rebounding, but how does the tallest player in the NBA keep hitting all those threes?
Chef J. Kenji López-Alt Talks Curiosity, Cuisine, and Science
IFT FIRST keynoter shares the importance of connecting culinary creativity with scientific inquiry, curiosity, and regional flavors to inform the future of food.
Federal judge refuses to block Trump order to create federal voter list and limit mail voting
U.S. District Judge Carl Nichols, a Trump appointee in Washington, late Wednesday rejected the request by Democrats and civil rights groups that had argued President Donald Trump’s order would likely be found unconstitutional.
Judge hands Trump mail-ballot win for now as Democrats’ next move looms
A federal judge ruled Democrats' bid to block Trump's executive order on mail ballot delivery was premature since no agency has yet acted on it.
Judge refuses to block Trump order to create voter list, limit mail voting
The Trump-appointed judge rejected arguments by Democrats and civil rights groups that the provision exceeds the Republican president's powers
Judge refuses to block Trump order to create voter list, limit mail voting
The Trump-appointed judge rejected arguments by Democrats and civil rights groups that the provision exceeds the Republican president's powers
Browns Pour Cold Water On Hype Surrounding Deshaun Watson
There's been a lot of offseason hype surrounding Cleveland Browns quarterback Deshaun Watson. Watson, who was traded from Houston to Cleveland in a blockbuster move that has been dubbed one of the worst NFL trades in recent history, could be on the verge of a comeback. The Browns could be leaning ...
Biden's ghostwriter tapes lawsuit all about 'politics': Juan Williams
Fox News senior political analyst Juan Williams discusses why former President Joe Biden is suing the Justice Department to block the release of audio recordings on 'Special Report.'
Researchers block key protein that helps Parkinson’s spread through the brain
A newly identified protein called GPNMB may play a major role in helping Parkinson’s disease spread through the brain. Researchers discovered that immune cells release the protein in response to damaged neurons, creating a vicious cycle that speeds up brain cell degeneration. In early experiments, antibodies that blocked GPNMB stopped the toxic process from spreading between cells.
31 hours with the spit-shined Mina the Hollower (and 34 with the four games that came before it)
To truly appreciate Mina The Hollower, an extraordinary new throwback of a game, I sent myself to Yacht Club University. That’s not a real institution of higher learning, but it’s the best way I can explain much of the past several weeks as I prepared to play Mina by playing the four biggest game previously made by studio Yacht Club Games. I had expected Mina the Hollower, in development for six years for PC and consoles, to potentially be something special. A demo I tried in March had felt great. Mina the Hollower had an old-school premise: a singular move for its hero that felt so good to control and so rich with possibilities that, in the hands of skilled designers, it could be riffed on in various ways for the length of a full game. Mina’s core maneuver, her hollowing, made her sort of an upside down Super Mario. Nintendo’s hero jumps through the air, discovering power-ups at the apex of his jump by bonking overhead blocks, then defeating enemies by landing on them. Mina essentially jumps into the ground, digging (“hollowing”) into the earth to fetch buried treasure, then burrows for a short distance to emerge on the other side of a wall that hides treasure or an enemy that needs some battering. I wanted to understand how good Yacht Club was at making games. I wanted to see how far they’d come. If Mina was terrific—as I predicted it might be—I wanted to feel how they got there, one button press at a time. On May 6, 21 days before the writing of this review, I checked with Yacht Club Games co-founder and programmer David D’Angelo, to ask which of the studio’s games I should play to truly appreciate the new one’s design. “Hmmm all of them?” he wrote back. “Starting with Shovel Knight definitely is helpful,” he continued, referring to Yacht Club’s first game. He gave me a link to a spreadsheet of over 400 cheat codes that could help me out, if I found the game too tough.1 “Most folks say Specter of Torment is the least difficult and quickest to finish in terms of playtime, and [it] refines much of Shovel Knight,” he told me. “King of Cards is a big celebration of everything we did in [the Shovel Knight compilation] Treasure Trove— might work for you better if you’re a fan of shorter, Mario-style courses. And it’s probably the closest to Mina in terms of polish.” So that was that. Four games, none of which were required. Mina is a whole new game in a whole new world, best I can tell. I’d barely played that first Shovel Knight before and never the other three. I just thought it’d help. It did. It turns out that playing a game studios major works before their latest is very illuminating.
Kyle Busch death certificate reveals several health struggles in last days
NASCAR driver Kyle Busch had been suffering from pneumonia for “days to weeks,” triggering a “chain of events,” including sepsis, that resulted in his untimely death, according to a report. Busch’s sepsis progressed rapidly, within 24 hours turning into disseminated intravascular coagulation, which is the formation of small blood clots that ultimately block blood flow to the organs, per the ...
Trump calls Biden 'grossly incompetent' after DOJ lawsuit
President Donald Trump said he'd "like to see" former President Joe Biden's private conversations after the latter attempted to block their release.
Biden sues to stop Justice Department from releasing interview recordings
Former President Joe Biden is suing to block the House Judiciary Committee from obtaining, and potentially releasing, audio recordings and transcripts of conversations in 2016 and 2017 with the ghostwriter of his memoir.
Your health app may be failing you
Many seniors struggle with health apps and portals despite wanting to use them. Learn how to overcome digital health literacy barriers and stay safe.
Ebola, chemical plants and health, hantavirus, common colds, heat and more
As they say, bugs have ears. Public health has had a relentless May. Chemical plant (near) explosions, Ebola, hantavirus, and that's before you even get to the usual suspects: common colds, heat, and ticks. Here’s an attempt to keep you up to speed and, more importantly, what it means for you and your community. But first, an announcement: World Cup The World Cup starts in 15 days (not like anyone is counting down), and we are hanging TVs in the Health Security Operations Center. It’s going to be a gorgeous, chaotic celebration of basically every culture on earth. And it’s going to take a team effort—from communities to individuals, from public health to health care—to keep people healthy. That’s where you come in. If you’re going to the games or live within 30 miles of a stadium, we would love to hear from you. Sign up for a weekly survey here. Thanks to the more than 1,280 people who have already signed up…you will be hearing from us soon!! Global disease “weather report” Hantavirus: Two more cases The global count of cruise ship passengers with hantavirus has now increased to 13 cases (11 confirmed), with three deaths. The two new cases are overseas and among people who were already quarantining: A crew member in the Netherlands. A Spanish national passenger who was quarantining at home tested positive through daily monitoring. They are now in a biocontainment unit. In the U.S., everyone remains negative. There may be more cases, given that the incubation period of hantavirus (the time from exposure to infection) is 45 days. But this week, we will reach a major milestone: the median incubation window is 18 days, and that will pass on May 29. What this means for you: Your risk from this cruise ship outbreak remains essentially nil at this point. Ebola rages on in Central Africa Big thanks to Dr. Craig Spencer, a humanitarian physician who has treated and survived Ebola, for jumping in to provide the YLE community with an update. Craig, take it from here… The combined confirmed and suspected Ebola cases in DRC are now more than 1,000. All signs are pointing to a very long and catastrophic outbreak in Central Africa: This is a vast undercount. We know this because the test positivity rate is hovering around 50%, only 20% of contacts are being traced (and in some areas, no contacts at all), and more cases keep popping up with no known connection. This all points to widespread and undetected community transmission. This is in only a week of detection. Compared to previous outbreaks, the growth is very fast, as the huge West Africa outbreak in 2016 was first detected at 49 cases and rose to 208 cases a month later. It took four months for that outbreak to reach the size of the current one in the DR Congo. The cases are spread out across 16 health zones. There are now multiple epicenters, making containment very difficult. Next door in Uganda, the case count is seven. While this number is low compared to DRC, a concerning development is that two health care workers recently tested positive with uncertain exposure histories. If they weren’t treating known Ebola cases, this means it’s spreading undetected in Uganda as well. On the ground, backlash, including the burning of health centers, has emerged, a pattern seen in nearly every outbreak and rooted in deep community distrust. It often stems from outside actors working in communities without fully understanding or addressing local priorities. Affected populations may recognize the severity of Ebola while still holding other concerns as more pressing, such as where their loved ones are buried. Community trust is essential to an effective response, but difficult to build during an active emergency. It is best established long before a crisis begins. U.S. priorities are made clear, and may backfire. The U.S. Administration has shown that its first priority is keeping Ebola out, with helping end the outbreak in the DRC a secondary concern. That's meant travel restrictions broader than anything we've imposed before — covering travelers from across the region, and reportedly some green card holders and permanent residents as well. For example, just these past two days, news broke that high-risk American travelers will be subject to a mandatory quarantine in Kenya before they are allowed to return. If an American is infected, the U.S. government plans to send them to a hospital it is standing up from scratch in Kenya. (Currently, Americans who were in the area are allowed to return but are diverted to three airports—Houston, Atlanta, and DC—for further screening.) Past administrations have used travel notices and stepped-up screening; this goes much further. At first blush, these strict precautions may sound prudent. But this approach could backfire in three ways: Restrictions this blunt give people every reason to hide where they’ve been and whom they’ve been near — making the people we most need to find harder to track, not easier. They also breed a false sense that this is someone else’s problem. But diseases are humbling. They find the small cracks in even the most impenetrable-seeming defenses. Lives lost. There is no treatment for this Ebola strain, which means survival depends heavily on the quality of the health system. We have that system in the States, but we are choosing not to use it for infected Americans. This is unbelievable and infuriating. (See a deeper dive from me here.) The only real way to lower the risk to Americans — and everyone else — is to end the outbreak in the DRC and across the region. What this means for you: If you have travel plans to this region, it’s time to cancel them. This is a high-risk situation in Central Africa, and CDC released a Level 4 Travel Advisory. There is also great uncertainty if and when the Administration will let you back in. To the general public in the U.S., your risk remains very, very low right now. U.S. disease “weather report” Ticks: past peak season? Good news, especially for people in the Northeast and Midwest: tick numbers continue to decline. Though we are at the peak of the season, this unusually early year is trending favorably. Heat-related illnesses in the North Heat risk is certainly not blanketing the entire country yet, but this week it will be moderate in the Midwest and the Southeast. What this means for you: Be sure to check the CDC HeatRisk tool. A red day isn’t the best day for that soccer game for a kid with asthma, and a stretch of orange days is a great time to check on your elderly neighbor. Common colds surging As far as respiratory viruses go, the only thing really going around right now is the common cold. It is higher this year than last year, but should peak very soon before returning this fall. Spotlight: Chemical plants Over the weekend, YLE California covered the serious situation that unfolded around a chemical plant in Orange County, California. Thankfully, the worst-case scenario (a chemical explosion) was mitigated, but only through luck. The health implications in a densely populated area could have been catastrophic. As the situation was winding down, another chemical explosion struck Washington State. This one was fatal. Health officials say the risk to surrounding residents from chemicals in the air and ground remains low, though the community deserves far greater clarity. Clean air and clean water consistently rank as Americans’ top public health concerns — yet when chemical disasters strike, communities are too often met with reassurances rather than transparency and accountability. Residents near the 2023 East Palestine, Ohio train derailment, for example, are still waiting to understand the long-term impact on their health, with few clear answers. What this means for you: Many are wondering if facilities processing potentially dangerous materials are in their neighborhoods. This interactive map allows you to enter your ZIP code and see all facilities monitored by the EPA, including any violations. Good news Ebola vaccines and treatment for the Bundibugyo species are in development. Two vaccine platforms are being explored, at least one of which may be deployable in as little as 2 months. One vaccine is being developed by Oxford, and the other uses the same biotechnology as the FDA-approved Zaire species of Ebola. (It may provide cross-protection, but it’s unclear at this point.) On the treatment side, two promising monoclonal antibody cocktails are likely to be deployed, though doses are limited and logistical hurdles remain significant challenges. Anni over at The Biotech Tea had a great explainer about the Ebola vaccine gap, if you want to read more. [ The Biotech Tea The Ebola vaccine gap, reading vessel damage, & the Makary exit 🗝️ Paid subscribers get the Biotech Term of the Week at $30/year (~$2.50/month). I try to keep it intentionally accessible, but if cost is ever a barrier, send me a message. A few people asked about expensing your subscription, so I put together a short email template… Read more 6 days ago · 10 likes · Annicka Evans, PhD ](https://www.thebiotechtea.com/p/the-ebola-vaccine-gap-reading-vessel?utm_source=substack&utm_campaign=post_embed&utm_medium=web) Polycystic ovary syndrome (PCOS) has been officially renamed polyendocrine metabolic ovarian syndrome (PMOS), following more than a decade of debate and input from roughly 22,000 clinicians, researchers, and patients worldwide. This is good because the old name was medically misleading, leading to patients without visible cysts being dismissed or overlooked entirely. The WHO estimates that 70% of people with the condition remain undiagnosed. A more accurate name should improve recognition, reduce stigma, and ultimately help the millions of people living with this condition get diagnosed and treated sooner. Poll Loading... Bottom line Public health situations are everywhere right now. Staying healthy takes public health professionals and systems working tirelessly behind the scenes and each of us showing up for our neighbors and communities. Love, YLE Big thanks to Ed Nirenberg for staying on top of the Ebola vaccines, Hannah Totte for all the figures, Dr. Craig Spencer for the Ebola insight, and Dr. Matt Willis for covering the chemical situation in CA. Your Local Epidemiologist (YLE) comprises a team of experts, ranging from physicians to immunologists to epidemiologists to nutritionists, working together with one goal: to “Translate” ever-evolving public health science so that people are well-equipped to make evidence-based decisions. YLE suite of newsletters reaches over 475,000 people across more than 132 countries. This newsletter is free to everyone, thanks to the generous support of fellow YLE community members. To support the effort, subscribe or upgrade below: Subscribe
Trump lashes out at Biden over suing DOJ to hide interview audio files
Former President Biden sues the Justice Department to block audio recordings from special counsel Robert Hur's classified documents investigation.
CVS sues Tennessee in latest challenge to state PBM laws
The same day that Tennessee Gov. Bill Lee signed a bill that would force pharmacy benefit managers to divest from retail pharmacies, CVS Health filed a lawsuit to block its implementation.