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The 90-day business reset every real estate agent should do before 2027

A 90-day reset helps agents audit lead sources, rebuild databases, and tighten systems, then make 3 decisions for 2027.

housingwire.com logo
Oct 8 • 11:00 AM EDT • Business • housingwire.com
Facing tight race, Gov. Tina Kotek taps friendly influencers to spread message

The Democratic governor has granted in-person interviews to a cast of social media users this year.

opb.org logo
Oct 9 • 9:00 AM EDT • Politics • opb.org
In tight WA House race, sparks fly over safety at challenger’s business

Questions about safety at Braun Northwest have become a flashpoint in a Southwest Washington district grappling with a deadly tank collapse at a Longview mill.

seattletimes.com logo
Oct 19 • 9:59 PM EDT • Politics • seattletimes.com
New PS5 Update Is Out Now, And Sony May Be Tightening Security Before GTA 6

Is there more to this new PS5 firmware update than just improved stability?

gamespot.com logo
Oct 21 • 9:46 AM EDT • Technology • gamespot.com
Vietnam's banks tap investors for $7 billion as economy runs red hot

Vietnamese banks are planning nearly $7 billion in share sales as the country's fast-growing economy fuels demand for capital, opening a window for foreign investors to expand in the tightly controlled sector.

reuters.com logo
Oct 6 • 9:02 PM EDT • Business • reuters.com
Apple enters new product category with HomeView device

If the HomeView takes off, Apple will have tightened its grip on its ecosystem, making it harder to move to a rival like Google or Amazon.

businessinsider.com logo
Oct 13 • 9:11 AM EDT • Business • businessinsider.com
Wolverines Zack Marshall Releases Statement after leaked text messages

On Monday night, there were leaked text messages surfacing across the internet about Michigan Wolverines tight end Zack Marshall being critical of offensive coordinator Jason Beck. Well, Marshall released a statement on his Twitter on Tuesday afternoon and said, What…

sports.yahoo.com logo
Oct 6 • 2:15 PM EDT • Sports • sports.yahoo.com
They helped elect Gluesenkamp Perez. Now some won't vote for her

As Rep. Marie Gluesenkamp Perez faces a tight reelection race against GOP state. Sen. John Braun, some Democrats want to punish her, while others fear losing her seat.

seattletimes.com logo
Oct 11 • 9:00 AM EDT • Politics • seattletimes.com
More Brock Bowers stat madness

Star tight end makes history every week

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Oct 14 • 10:01 AM EDT • Sports • sports.yahoo.com
Apple's new hardware strategy capitalizes on trust — just in time for the AI era

Apple's smart home strategy is about selling more hardware. But it's also about more tightly binding iPhone customers to its ecosystem.

finance.yahoo.com logo
Oct 14 • 6:00 AM EDT • Technology • finance.yahoo.com
Seahawks injury update: Elijah Arroyo’s season is over

The Seahawks tight end will end his sophomore campaign with only one catch.

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Oct 22 • 3:05 PM EDT • Sports • sports.yahoo.com
😐 Neutral (0%)
Trump Endorses Netanyahu as Best U.S. Partner in Tight Israeli Election

The president praised the embattled prime minister for his endurance, saying any other candidate would be the “wrong Leader.”

nytimes.com logo
Oct 18 • 11:16 AM EDT • Politics • nytimes.com
Former Buccaneers tight end Devin Culp signs with Browns

Former Buccaneers tight end Devin Culp has signed with the Cleveland Browns' practice squad after being released by Tampa Bay in September.

sports.yahoo.com logo
Oct 14 • 8:05 AM EDT • Sports • sports.yahoo.com
Suburban women souring on Paxton could doom him in tight race

Interviews with these voters reveal a combination of apathy toward his candidacy and an active shift by some toward his Democratic opponent.

detroitnews.com logo
Oct 19 • 10:48 AM EDT • Politics • detroitnews.com
Republican congressman tries to outrun a potential blue wave in New York toss-up seat

Rep. Mike Lawler, R-NY, is in a tight race for re-election in a toss-up district that could help determine control of Congress in November.

kgou.org logo
Oct 9 • 5:00 AM EDT • Politics • kgou.org
This Trade For A Tight End Could Energize Denver's Offense

The Denver Broncos need to add to their offense, and a trade for this Eagles tight end could help.

sports.yahoo.com logo
Oct 22 • 5:11 PM EDT • Sports • sports.yahoo.com
Tighter data center rules on Fort Smith Board agenda

The Fort Smith Board of Directors is set to vote Tuesday (Oct. 6) on an ordinance that would give the city more oversight of any planned data center development within...

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Oct 5 • 3:05 PM EDT • Business • talkbusiness.net
Kansas’ 94-year streak is unlike anything else in American politics

Democrats are dreaming of a revolution in Kansas in November, trying to believe in polling that shows a tight race in the Senate contest there between the Democrat, Rev. Adam Hamilton, and the Republican incumbent, Sen. Roger Marshall.

cnn.com logo
Oct 7 • 5:00 AM EDT • Politics • cnn.com
Voters in 12 states face tight races for governor

The Cook Political Report has labeled four governor races as "lean Democrat" and three as "lean Republican."

spectrumlocalnews.com logo
Oct 6 • 6:40 PM EDT • Politics • spectrumlocalnews.com
Michigan Senate Candidates Make Dueling Pitches to Business Leaders in Detroit

Mike Rogers and Dr. Abdul El-Sayed, the candidates in the tight race, defended their economic policies at the Detroit Economic Club.

nytimes.com logo
Oct 20 • 5:40 PM EDT • Business • nytimes.com
When 1 + 1 = 1: The Miserable Math Behind Many Media Mergers

(Welcome to the “Most Important Story of the Week”, my bi-weekly strategy column analyzing the most important (but often not buzziest) news story of the last two weeks. I’m the Entertainment Strategy Guy, a former streaming executive who now analyzes business strategy in the entertainment industry. Please subscribe.) The last few issues of this newsletter have circled two topics: September’s streaming viewership and all the Paramount/Skydance/Warner Bros./Discovery merger news. I’m happy to say on the Streaming Ratings Report front, we’ll be all caught up by early next week, then the SRR will come out on a tight weekly schedule. Then, after today, I’ll have slayed my PSWbD dragon. It’s such a big story, it demanded multiple issues. With the announcement of a name (just Skydance) and executive team, though, I think we can almost close the book on this story. In terms of topics, it becomes just another studio to cover. So today, I have one last set of takes on that merger. As I’ve sat with it, reading about who was staying and who was going, a big worry crystallized in my brain, and I gotta get that take out. Plus, I still owe you a host of “ugliness” that didn’t fit in my previous “The Good, The Bad and The Ugly” takes. Let’s dive in! Subscribe Most Important Story of the Week - As Paramount Shuffles Deck Chairs, Will They Build or Consolidate? On social media—I try to avoid most social media platforms, but sometimes I end up checking in—the best joke I saw about the announcement of the new name of Skydance was from fellow reporter Claire Atkinson who pointed out… Yeah, I laughed out loud at that one. Later, though, I saw another Twitter response (that later got deleted, so I can’t shout the person out) that did give me pause. The person noted that the Titanic film made the better analogy: a super expensive project everyone in the town doubted that went on to conquer the globe. So yeah: on one hand, the image of the Titanic recalls the actual ship and its infamous end, but that clip is from a movie which proved the doubters wrong. So for all the skepticism of the latest massive media merger, one could wonder which way this one goes. Does it crash like the Titanic or rise to glory like Titanic, the movie? Either way, this deal is “Titanic”, looking at the massive debt required to close the deal, which is not going well when it comes to borrowing costs for Paramount… …or borrowing costs for Oracle. But I’ve started to get worried about another outcome: the sum of this merger will be smaller and weaker and less profitable than its former parts. In other words, one plus one won’t equal three or two, but an even smaller number. Skydance paid to take a traditional studio off the board, but they won’t really capture the upside. Let me explain what I mean, but first, let’s look at the series of news that inspired this thought. Skydance Sets Its Leadership Team As soon as the Paramount-Skydance-Warner Bros.-Discovery merger closed, the new leadership team announced a new name—Skydance, which I’ll use going forward—and a new executive leadership team. You’ve probably read through all the executive shuffling, but if you haven’t, here’s a quick, incomplete summary, in rough order of importance: Mattel’s CEO Ynon Kreiz—who previously ran Maker Studios—joined as co-CEO with David Ellison. HBO/HBO Max’s Casey Bloys will stay and run streaming. Former head of streaming for Paramount-Skydance Cindy Holland—who was also at Netflix—will depart. The former heads of Warner Bros.—Pam Abdy and Mike De Luca—are out. The film studios will be run by Dana Goldstein and Josh Greenstein. George Cheeks of Paramount will run Skydance TV, controlling all the TV production units. In comic book news, the DC films will still be run by Peter Gunn and Peter Safran. Lastly, the head of CNN, Mark Thompson, will stay in place. Let’s quickly opine on the particulars before diving into the broad ramifications. We’re just getting started with this issue, but the rest is for paid subscribers of the Entertainment Strategy Guy, so if you’d like to find out… Who I like and dislike in their next gigs… Why I think this consolidation will likely leave Skydance worse off… The math behind which mergers succeed and which don’t… A lot more ugliness in this merger… And a whole lot more... ...please subscribe! We can only keep doing this great work with your support.

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Oct 13 • 3:20 PM EDT • Entertainment • entertainment.substack.com
Roger Marshall praises Trump's tariff policies after Kansas executive says they hurt his business

U.S. Sen. Roger Marshall, locked in tight campaign with Democrat Adam Hamilton, throws full support behind President Donald Trump's tariff war.

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Oct 16 • 1:20 PM EDT • Business • kansasreflector.com
Pharaoh Brown signed to roster

The Colts added depth to their tight end room on Tuesday.

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Oct 13 • 3:36 PM EDT • Sports • sports.yahoo.com
Tigers pitcher Troy Melton given clean bill of health entering offseason

Right-hander ended solid 2026 season early because of tightness in his right forearm.

detroitnews.com logo
Oct 15 • 10:58 AM EDT • Health • detroitnews.com
Travis Kelce Is Doing Something Remarkable at 37 Years Old

Travis Kelce turned 37 on October 5th, and usually, that's about the time an NFL tight end starts thinking about life after football. Kelce's numbers suggest he's got other plans. Through four games, the Kansas City Chiefs veteran is averaging more yards per catch than he has in years, and Patrick Mahomes is still finding …

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Oct 14 • 12:52 AM EDT • Sports • sports.yahoo.com
Brock Bowers rolls up big numbers again in Week 5

Las Vegas Raiders tight end Brock Bowers posted eight receptions for a game-high 110 yards and a touchdown on 10 targets in Week 5

sports.yahoo.com logo
Oct 11 • 9:32 PM EDT • Sports • sports.yahoo.com
Communities worry for their health after Trump weakens pollution limits: 'It's a kick in the gut'

Biden-era changes to the Clean Air Act would have tightened regulations for industrial sites, but the Trump administration has given exemptions to hundreds of facilities. People living near the sites are concerned about air quality and their well-being.

kcur.org logo
Oct 7 • 5:00 AM EDT • Health • kcur.org
State of Texas: Tight races test voters, parties and a new political map

The race for U.S. Senate is the biggest story in Texas politics, and it's getting nationwide attention. Campaign spending between Ken Paxton and James Talarico is on pace to set records, and the race ...

yahoo.com logo
Oct 17 • 7:00 PM EDT • Politics • yahoo.com
Midterm polls show tightening races in Oregon and Washington

Oregon and Washington’s midterm elections are shaping up to be tighter than expected.

koin.com logo
Oct 11 • 5:00 PM EDT • Politics • koin.com
Fantasy Football Week 5 tight end rankings

Find out which tight ends to play this week in fantasy football.

sports.yahoo.com logo
Oct 8 • 11:00 AM EDT • Sports • sports.yahoo.com
Former Buccaneers Draft Pick Signs With Browns

When the Tampa Bay Buccaneers waived their former seventh-round pick, Devin Culp, before his third NFL season, he cleared waivers and did not find a new team right out of the gate. However, before the Cleveland Browns‘ Week 6 matchup against the Baltimore Ravens, the team decided to sign the Bucs’ former tight end to their […] The post Former Buccaneers Draft Pick Signs With Browns appeared first on HEAVY.

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Oct 13 • 9:07 PM EDT • Sports • sports.yahoo.com
NVIDIA Denies RTX 5090 Discontinuation Rumors, Admits Supply Is Tight

NVIDIA has finally responded to reports that the GeForce RTX 5090 is being discontinued. Jeff Fisher, senior vice president of NVIDIA's personal computing business, told Taiwanese media after the RTX Spark launch party in Taipei on October 16 that the rumors aren't true, as reported by 4Gamers...

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Oct 17 • 10:27 AM EDT • Technology • techpowerup.com
GOP states have made it harder to vote. The changes could swing tight races

GOP lawmakers and officials around the country have enacted voting restrictions that could affect turnout in key races.

cnn.com logo
Oct 16 • 5:00 AM EDT • Politics • cnn.com
Trump’s Overtures to Putin Put Republican Candidates in Hot Seat

GOP politicians in a number of tight races are breaking with Trump on Russia policy ahead of midterms.

wsj.com logo
Oct 18 • 5:25 PM EDT • Politics • wsj.com
The real reasons US politicians are getting older

No country for young men and women: why do older politicians seem to have such a tight grip on the US political system?

bbc.com logo
Oct 21 • 7:52 PM EDT • Politics • bbc.com
Report: Leaked Michigan Texts Rip Jason Beck’s Offense

Leaked group chat messages have Michigan's tight ends turning on Jason Beck's offense during the bye week. #GoBlue

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Oct 6 • 10:50 AM EDT • Sports • sports.yahoo.com
Michigan tight end Zack Marshall apologizes after he ripped OC Jason Beck in leaked texts
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Oct 6 • 1:32 PM EDT • Sports • sports.yahoo.com
200 supporters rally for Hinojosa as Abbott is expected to campaign in Houston-area this week

Democratic candidate for governor Gina Hinojosa rallies with supporters the day before the state of early voting. The race has tightened in recent weeks. Governor Greg Abbott is also expected to spend time in the southeast Texas this week.

houstonpublicmedia.org logo
Oct 19 • 9:32 AM EDT • Politics • houstonpublicmedia.org
Trump ramps up attacks on Dems in tight races

President Trump is intensifying personal and Islamophobic attacks on Democratic candidates in several states as Republicans worry about a voter-enthusiasm gap ahead of the November 3 elections. CNN’s Alayna Treene reports from a rally in Northern Kentucky.

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Oct 17 • 8:00 PM EDT • Politics • cnn.com
Scientists discover cell division does more than make new cells: It helps reshape tissues

Every time a tissue grows or renews itself, cells must divide inside an already crowded environment. That creates a fundamental problem that scientists have not fully understood: How does a tightly packed ...

phys.org logo
Oct 16 • 6:20 PM EDT • Science • phys.org
State of Texas: Tight races test voters, parties and a new political map

The race for U.S. Senate is the biggest story in Texas politics, and it’s getting nationwide attention. Campaign spending between Ken Paxton and James Talarico is on pace to set records, and …

kxan.com logo
Oct 17 • 7:00 PM EDT • Politics • kxan.com
Could Texas Elect a Democratic Governor for the First Time in More Than 30 Years? Polls Show a Tight Race

Republicans have led the state for more than 30 years. But Gov. Greg Abbott appears to be facing an unusually competitive bid from his Democratic challenger.

time.com logo
Oct 6 • 5:46 PM EDT • Politics • time.com
Deep dive
😐 Neutral (12%)
wow
51%
ahah
26%
love
23%
Colts Activate Tight End from IR Ahead of Titans Matchup

The Indianapolis Colts have activated tight end Will Mallory from Injured Reserve and removed him from the injury report for Sunday's game against the Tennessee Titans.

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Oct 18 • 6:41 AM EDT • Sports • sports.yahoo.com
Where is TE Gunnar Helm in this Titans offense?

Tennessee Titans sophomore tight end Gunnar Helm hasn’t made the desired impact in 2026. What’s going on?

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Oct 7 • 9:30 AM EDT • Sports • sports.yahoo.com
On Byron Donalds campaign stop in Sarasota, crowd cheers for keeping Florida red

Polls show Donalds in the lead, though it's a tight race with 12 days to go until the election.

wusf.org logo
Oct 22 • 5:31 PM EDT • Politics • wusf.org
Hospitals are selling their real estate. The deals may prove costly

Health systems are selling hospital real estate to raise cash for operations and growth, but higher rents and tighter oversight add new pressure.

modernhealthcare.com logo
Oct 16 • 6:00 AM EDT • Health • modernhealthcare.com
Michigan GOP Senate nominee Mike Rogers on whether Iran war was a mistake: ‘We’ll find out’

Rogers and Democrat Abdul El-Sayed spoke to “NBC Nightly News” about Iran, the economy and the issues driving the tight Michigan Senate race.

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Oct 14 • 5:13 PM EDT • Politics • nbcnews.com
High-Signal Publisher
Brown, Acton snag leads in tight races, according to recent polling

The poll results come as early voting begins in Ohio.

crainscleveland.com logo
Oct 6 • 9:51 AM EDT • Politics • crainscleveland.com
PS5 to Integrate Anime into Main Menu as Sony Tightens Ties with Crunchyroll

"Anime and gaming have overlapping communities"

pushsquare.com logo
Oct 7 • 5:45 PM EDT • Technology • pushsquare.com
What Dueling Visits by Ocasio-Cortez and Manchin Say About Maine’s Senate Race

Senator Susan Collins, a Republican in a tight race, is keying her closing pitch to the middle, while her progressive challenger, Troy Jackson, is seeking to excite the left.

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Oct 22 • 6:06 PM EDT • Politics • nytimes.com
In tight WA House race, sparks fly over safety at challenger’s business

Questions about safety at Braun Northwest have become a flashpoint in a Southwest Washington district grappling with a deadly tank collapse at a Longview mill.

seattletimes.com logo
Oct 19 • 9:59 PM EDT • Business • seattletimes.com
Communities worry for their health after Trump weakens pollution limits: 'It's a kick in the gut'

Biden-era changes to the Clean Air Act would have tightened regulations for industrial sites, but the Trump administration has given exemptions to hundreds of facilities. People living near the sites are concerned about air quality and their well-being.

wpr.org logo
Oct 12 • 3:26 PM EDT • Health • wpr.org
Week 5 fantasy tight end rankings: Top TE streamers, starts

A huge under-the-radar fantasy standout this season has been Juwan Johnson, who is the TE3 through the first four weeks. Is he a top-5 pick in Week 5?

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Oct 6 • 12:48 PM EDT • Sports • sports.yahoo.com
Blue shift: Yet another political forecaster shifts CD 25 race in Jared Moskowitz’s favor

‘The race doesn’t appear to have tightened, so we’re shifting it.’

floridapolitics.com logo
Oct 16 • 12:06 PM EDT • Politics • floridapolitics.com
How Small Pharmacy Expansion Will Impact CVS Health (CVS) Investors

CVS Health has been rolling out smaller pharmacy focused stores, expanding MinuteClinic sites and raising its 2026 revenue and earnings outlook, alongside new efforts in benefit transparency and women’s midlife health research. The push into underserved neighborhoods with compact pharmacies and clinics points to a tighter focus on access, operating efficiency and aligning physical sites with where prescription demand actually shows up. This article examines how CVS Health’s investment...

finance.yahoo.com logo
Oct 21 • 1:17 AM EDT • Health • finance.yahoo.com
Communities worry for their health after Trump weakens pollution limits: 'It's a kick in the gut'

Biden-era changes to the Clean Air Act would have tightened regulations for industrial sites, but the Trump administration has given exemptions to hundreds of facilities. People living near the sites are concerned about air quality and their well-being.

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Oct 11 • 8:06 AM EDT • Health • nebraskapublicmedia.org
Top Republican super PAC pledges $5 million for South Carolina Senate race

The Senate Leadership Fund’s commitment comes amid a tight contest between GOP Sen. Darline Graham and Democratic challenger Annie Andrews.

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Oct 6 • 10:12 AM EDT • Politics • nbcnews.com
High-Signal Publisher
Donalds blitzes airwaves as governor’s races tightens

TALLAHASSEE — U.S. Rep. Byron Donalds’ gubernatorial campaign is hitting the airwaves with a spate of new ads amid a tightening race, as he seeks to maintain the GOP’s hold

keysnews.com logo
Oct 7 • 11:00 AM EDT • Politics • keysnews.com
Voters in 12 states face tight races for governor

The Cook Political Report has labeled four governor races as "lean Democrat" and three as "lean Republican."

spectrumlocalnews.com logo
Oct 6 • 6:40 PM EDT • Politics • spectrumlocalnews.com
Political polls historically underestimate Phil Scott. Will 2026 be different?

Voters decide between Phil Scott and Amanda Janoo as late-season polls offer conflicting views on the tight Vermont race.

vnews.com logo
Oct 12 • 3:53 PM EDT • Politics • vnews.com
Businesses could be barred from non-essential water use amid supply threat

Golf clubs, private schools and car washes may face tighter rules from water companies as England’s drought continues

theguardian.com logo
Oct 14 • 2:00 AM EDT • Business • theguardian.com
NFL looking into an official cursing at Cardinals tight end Trey McBride

Line judge Jeff Seeman was caught on camera cursing at McBride, which drew the ire of union leader JC Tretter

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Oct 5 • 9:09 AM EDT • Sports • spectrumlocalnews.com
International Business Machines (IBM) Unveils Real Time App Security Collaboration

International Business Machines (NYSE: IBM) announced a new collaboration with Zscaler and Red Hat to tighten application security for enterprise clients. The joint effort combines IBM and Red Hat software platforms with Zscaler threat intelligence to provide real-time protections at the application layer. The partners plan to coordinate vulnerability discovery, automated policy updates, and validated software remediation workflows for shared customers. This IBM, Zscaler and Red Hat security...

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Oct 10 • 11:16 PM EDT • Business • finance.yahoo.com
Steam Pricing Analyst Found Hollow Knight: Silksong's $20 Price Annoying: 'I Was A Bit Like, Oh God, Please Price It Higher'

Indie devs are facing tighter pricing pressures than ever

kotaku.com logo
Oct 22 • 2:00 PM EDT • Technology • kotaku.com
Kenyon Sadiq still in concussion protocol

New York Jets tight end Kenyon Sadiq remains in the concussion protocol after leaving the Week 5 game

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Oct 12 • 10:41 PM EDT • Sports • sports.yahoo.com
‘Play On!’ hits all the right notes

The English Renaissance meets the Harlem Renaissance in “Play On!,” a sparkling show that marries a loose adaptation of Shakespeare's “Twelfth Night” with the music of Duke Ellington. Conceived by Sheldon Epps, who also directed the original 1996-97 production (first in San Diego, then on Broadway), the show is getting a marvelous revival under his direction to open Chicago Shakespeare Theater's 40th anniversary season.While the title “Play On!” refers to the famous quote about music being the food of love and thus to the dozens of Ellington songs—among them “It Don’t Mean a Thing,” “Don’t Get Around Much Anymore,” “I Got It Bad (And That Ain't Good),” “Solitude” and “I’m Beginning to See the Light”—incorporated into the plot, one of the highlights for me is the clever way Cheryl L. West's book reworks the story. Apparently, it's also been updated for this outing, among other things to give the women more agency. In the big opening number (there's a six-piece, horn-heavy onstage band), aspiring songwriter Vy (Hailee Kaleem Wright) is the one to “Take the 'A' Train” to “Drop Me Off in Harlem.” She wants to meet the famous Duke (Edred Utomi) — Ellington, not Orsino, that is — and she seeks the help of Jester (an engaging James Harkness) to find out how. When Jester tells her in no uncertain terms that the music industry is a man's world, she disguises herself as Vy-Man and persuades the Duke to listen to one of her songs. He's suffering from a creative block because he's pining for Lady Liv (Krystal Joy Brown), queen of the Cotton Club, and convinces Vy-Man to bring the Lady the song as if the Duke had written it, promising to reward her with employment. Vy reluctantly complies, and the predictable complications ensue. Lady Liv is attracted to Vy-Man, while Vy is attracted to the Duke and he to Vy, though it disturbs him because he thinks she's a man. The fallout when the deception comes to light bodes ill—at least for a while.Here's where West's book cannily diverges from Shakespeare. Vy's twin brother Sebastian really is dead, so West devises another love interest for Lady Liv basically by rehabilitating the Malvolio character, here named Rev (Alan H. Green), the Lady's uptight, self-important manager. His unrequited love for her is magically transformed after he gets his comeuppance (minus the torture) from Miss Mary (Alanna Lovely), her honey Sweets (James Earl Jones II) and Jester, the stand-in for Sir Toby, who has romantic problems of his own with a woman named CC (Kaylah Janssen). In other words, Rev gets the girl — and also a show-stopping yellow zoot suit from costume designer An-Lin Dauber. All the costumes are dandy, though those for the men have more pizzazz than the women's day dresses. The bilevel, slanted scenic design by Beowulf Boritt brings 1930s Harlem to life in a slightly expressionistic way with the help of Adam Honoré's lighting and Ray Nardelli's sound design. Edgar Godineaux's choreography adds to the period feel, though there could be even more of it.Most of all, the leads have splendid voices, and the performances are terrific. Green's Rev and Harkness's Jester get my vote for comedy chops, and Brown's Lady Liv probably will stay with me the longest for her complexity and big blues number, “I Ain't Got Nothin' But the Blues.”

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Oct 12 • 3:30 PM EDT • Entertainment • hpherald.com
OU's goal remains the same: 'Make the playoffs'

Following the 21-13 loss to No. 12 Kentucky on Saturday night, OU defensive backs Omarion Robinson and Reggie Powers and tight end Hayden Hansen recapped the game.

oudaily.com logo
Oct 20 • 11:28 AM EDT • Sports • oudaily.com
Clemson lands second commitment in 2028 recruiting class

The Clemson Tigers have landed a commitment from 2028 tight end Wright Martin. He is their second commit in the 2028 cycle.

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Oct 15 • 12:58 PM EDT • Sports • sports.yahoo.com
Mike Ditka tributes pour in from former President Obama, Chicago's sports teams and around the NFL

Mike Ditka was “Iron Mike” as a player who revolutionized the tight end position and later became the easily recognizable and often imitated fiery, mustached and sweater vest-wearing “Da Coach” of the Chicago Bears during a Super Bowl-winning tenure.Ditka died Friday at 86, his family announced in a statement.

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Oct 9 • 4:59 PM EDT • Sports • sports.yahoo.com
Analysis | Home heating oil is a sleeper campaign issue across cold-weather battlegrounds

As the weather grows cold in key battlegrounds nationwide, sky-high home heating oil prices could tilt a series of tight races.

washingtonpost.com logo
Oct 19 • 5:24 AM EDT • Politics • washingtonpost.com
Raiders Star Tight End Listed As Limited In Practice

Las Vegas Raiders tight end Brock Bowers recently underwent a knee procedure, and his recovery remains ongoing.

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Oct 8 • 8:27 AM EDT • Sports • sports.yahoo.com
In tight Texas Senate race, Trump's immigration crackdown tests Republicans' hold on voters

The race between Democrat James Talarico and Republican Ken Paxton is hotly contested and enormously expensive, with total ad spending topping $500 million.

yahoo.com logo
Oct 18 • 6:00 AM EDT • Politics • yahoo.com
Is the Texas Senate race tightening?

Unbiased Politics News

thehill.com logo
Oct 16 • 12:55 PM EDT • Politics • thehill.com
Trump uses antisemitic slur to defend GOP Kansas senator

GOP Kansas Sen. Roger Marshall Marshall is locked in an unexpectedly tight reelection battle against Democrat Adam Hamilton in what might be the biggest surprise of the midterms.

seattletimes.com logo
Oct 20 • 12:14 PM EDT • Politics • seattletimes.com
Trump, Vance to headline three Ohio rallies in 10 days

The campaign stops point to growing GOP anxiety over the tight Senate race between Sen. Jon Husted and former Sen. Sherrod Brown.

spectrumnews1.com logo
Oct 6 • 5:02 PM EDT • Politics • spectrumnews1.com
After a rash of burglaries at South Side establishments, Black business owners are wondering: ‘Why us?”

Business owners are coming together and demanding tighter security after a rash of burglaries targeting Black-owned businesses on Chicago’s South Side.

wbez.org logo
Oct 14 • 5:24 PM EDT • Business • wbez.org
😐 Neutral (7%)
angry
50%
love
50%
Trump, Vance to headline three Ohio rallies in 10 days

The campaign stops point to growing GOP anxiety over the tight Senate race between Sen. Jon Husted and former Sen. Sherrod Brown.

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Oct 6 • 5:02 PM EDT • Politics • spectrumnews1.com
UK’s Oxford Metrics warns about annual loss on entertainment industry spending cuts

Oct 9 (Reuters) - British smart sensing tech firm Oxford Metrics warned about an annual loss on Friday, hit ​by spending cuts and studio consolidation ‌across the film and TV industry and tighter research budgets, sending its shares 15% lower. Here are...

wkzo.com logo
Oct 9 • 3:57 AM EDT • Entertainment • wkzo.com
NFL suspends official Jeff Seeman for two games for swearing at Arizona Cardinals tight end Trey McBride

The NFL suspended two officials for separate incidents on Sunday, including Jeff Seeman after he was caught swearing at Arizonas Trey McBride; watch the second NFL London game of the season between the Jacksonville Jaguars and Philadelphia Eagles at 2.30pm Sunday, live on Sky Sports

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Oct 6 • 3:00 AM EDT • Sports • skysports.com
Taiz hospitals near collapse as Houthis tighten siege: Yemen government
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Oct 10 • 11:41 PM EDT • Health • aljazeera.com
‘They Want to Get Into the Taylor Swift Business’ — Media Analyst ‘Rationalizes’ Travis Kelce Possibly Coming in as Troy Aikman’s ESPN Replacement

Kansas City Chiefs tight end Travis Kelce re-signed with the franchise this offseason, and the Chiefs have come flying out of the blocks to a 4-0 record. Once the current season ends, however, there is some speculation about where Kelce may head next, particularly if it comes to a role in the broadcasting booth.

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Oct 18 • 6:19 AM EDT • Business • sports.yahoo.com
Can AI solve our mental health access problem?

Last week I asked you what worries you most about AI in health. It was close, but your top answer was “AI giving bad health advice.” Last week’s poll results: You’re in good company. This concern was top of mind at a conference I joined at Stanford last week, where researchers, clinicians, and people who build AI systems spent a day debating trust and safety in health AI. Stepping back, I’m also hearing your emerging concerns about AI’s impact on our well-being generally. I see this as a matter of public health, and we’ll take it in pieces as we learn together. Today we’ll focus on AI chatbots used for therapy for mental health. Early this month, Governor Newsom vetoed Senate Bill 903, California’s most ambitious attempt to regulate AI use for mental health. It’s at the center of active debate, and raises the questions patients, family members, citizens, and voters will face as AI moves deeper into health care. Let’s work through it. What is “AI-based therapy”? It’s really two things: purpose-built mental health apps designed to deliver structured support, and general chatbots like ChatGPT, Claude, and Gemini that people increasingly use for emotional support—even if they weren’t built for it. Spoiler alert: I don’t know whether the shift toward AI therapy is good or bad. The evidence isn’t there yet. But I do know it’s already happening, and I have some ideas about how we can roll it out with safety in mind. The therapy dilemma, in a nutshell Mental health challenges are common, and strain health and well-being across populations. Therapy (interactive dialogue with a trained, empathetic practitioner) helps many people heal. The demand for licensed therapists far exceeds the supply in California, and AI-based therapy can narrow that gap. AI-based therapy remains novel, unproven, and not well tested. Right off the bat, we can see we’re dealing with trade-offs here. Since the main driver of demand for therapy from a robot is lack of access to therapy from a human, we’ll start there. It’s too hard to find and afford a human therapist California is short roughly 55,000 licensed, non-prescribing therapists and counselors, about 40% of what we need. Psychiatrists, who rely on talk therapy as a complement to prescribed medications, are even more scarce. Eight counties have none, and density ranges from 1.7 per 100,000 residents in San Benito County, to 68.1 in Marin County. My wife is a psychiatrist in Marin, and even here access is tight. If it’s hard in the best-supplied county, imagine rural Sierra County, or the San Joaquin Valley. In 2024, more than half of Californians who tried to make a mental health appointment struggled to find a provider who took their insurance, compared with 14% for physical health care. When Senate staff posed as “secret shopper” patients and called 120 mental health providers in Medicare Advantage networks, they landed an appointment less than once for every five tries. Insurers pay behavioral health clinicians about 22% less than medical and surgical clinicians for comparable office visits. On top of that, billing denials and prior authorizations hit hardest at the solo and small practices common in mental health. Psychiatrists opt out of Medicare at the highest rate of any specialty. In many places, a cash practice for therapy fills quickly with patients paying $250 or more an hour, with no insurance paperwork at all. Families who can pay cash find providers more easily. Those who rely on insurance, including Medi-Cal enrollees, older adults, rural residents, and non-English speakers, compete for what’s left. So we can’t pretend the human system works, and we can’t blame people for turning to AI for support when they’re in distress. AI is filling the gap It’s estimated that roughly a quarter of AI users use it for mental health support. If you have internet, it’s available 24/7, it’s cheap, and it speaks your language. Uninsured adults are about twice as likely as insured adults to do it (30% vs. 14%). It feels anonymous in ways that may enable people to ask things they’re unsure or embarrassed about. The largely hidden, personal use makes it hard to study whether it’s actually helping people with their mental health issues, but researchers are trying. Does AI therapy work? A 2026 analysis of nearly 40 randomized trials found chatbots showed a real but small reduction in depression symptoms. But most of these trials were compared to an alternative of no therapy, not a human therapist. So the benefit of AI therapy is probably real, but modest, and mostly untested against the alternative of human contact. We need more studies. Serious concerns OpenAI’s own estimate is that more than a million ChatGPT users each week show signs of suicidal planning or intent. These are high stakes encounters, and AI doesn’t always get it right. That’s partly because a chatbot can sound like a therapist, but it has no license, no duty of care, and it’s not clear who to hold accountable when it gets things wrong. AI is also designed to help users in whatever task they’re seeking to accomplish. People may feel like they’re getting therapy, but they’re mainly getting a convincing conversation. It’s easy for an AI companion to wander into gray areas, like playing along with “creative writing” that may be about the user’s own suicidal intent. Courts are driving safety conversations A wave of lawsuits have been filed on behalf of families claiming that chatbots pushed people they loved toward self-harm, including teens who died by suicide. The first settlements came this year. OpenAI is headquartered in San Francisco, and dozens of cases alleging that ChatGPT drove users to suicide or self-harm are now before a San Francisco judge. Character.ai has filed for bankruptcy after several states brought lawsuits accusing the chatbot of pushing dangerous content to kids. But the technology seems to be improving. Last month, an independent evaluation found that newer AI models “almost never endorse suicide.” That’s progress, but our societal appetite for even one preventable death is very low. So how do we move forward? Finding a middle ground Earlier this month the governor vetoed Senate Bill 903, a bill designed to place guardrails on the use of AI for therapy. The bill would have prohibited any AI-based platform from being advertised as psychotherapy, and would have required a licensed professional to review and approve each encounter where AI was used to support therapeutic decisions. Newsom called it overly broad, since even routine screening questions would have needed clinician sign-off. Knowing we’re already short on mental health providers, requiring human review of AI encounters may not relieve our access problems. Still, the answer isn’t no oversight. Here’s one feasible short term solution. Rather than reviewing each encounter, a licensed clinician can design the guardrails: what counts as a crisis, what triggers an immediate handoff to a human, and what gets sampled for audit each month. The AI runs inside that structure. Conversations get checked, failures get reported, and a real clinician owns the framework. Medicine already has models to learn from. The FDA process for rolling out newly approved medications is an example. After a product reaches patients, we keep watching for adverse events. Patient-facing AI needs the same “digital pharmacovigilance”: systematic tracking of harms, near misses, and the types of groups that get hurt and why. It’s also critical that users know that they can reach a human if they’re in crisis. Most chatbots now include messages like these: Bottom line The rush to use unproven AI tools for mental health support is mostly a workaround, a sign of a health system people can’t get into. We need better access to proven care from licensed clinicians. That takes reimbursement that makes accepting insurance viable, and a bigger workforce. But, built and tested well, AI could be part of the answer. It could be the 2 a.m. check-in when no one else is awake, or a way for patients to practice skills their therapist taught them. It could be the first step to get someone the right level of care, and take paperwork off clinicians’ plates so they spend more time with patients. None of this is simple. The SB 903 veto doesn’t end the debate, and the legislature will be back. In the meantime, those of us using these tools need to stay informed, ask hard questions, and hold the companies building them accountable. I’ll try to do my part, and we’ll keep learning together. Love,Matt P.S. If you or someone you know is struggling with mental health challenges, emotional distress, substance use problems, or just needs to talk, call or text 988- you’ll reach a real person— or chat at 988lifeline.org 24/7. Dr. Matt Willis is the author of Your Local Epidemiologist in California. A California native, he’s served as a primary care physician, CDC epidemiologist, and public health officer for Marin County, where he guided the pandemic response. He lives in Marin with his family and their dogs, Teddy and Ramona. Thank you Cynthia He, MD, PhD, and Parnika Saxena, MD, for their guidance in preparing this article. Cynthia works in an outpatient mental health clinic, treating patients who have Medi-Cal or, sometimes, no insurance. Parnika works in an inpatient psychiatric unit, treating patients with public or private insurance or self-pay ability. All opinions are their own and do not represent their employers.

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Oct 16 • 10:32 AM EDT • Health • yourlocalepidemiologistca.substack.com
Packers tight end Kraft struggling with drops as he comes back from torn ACL

Green Bay’s Tucker Kraft said this summer he believed he was playing as well as any tight end in the NFL before tearing his anterior cruciate ligament last season.

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Oct 7 • 7:10 PM EDT • Sports • spectrumnews1.com
Rams TE Terrance Ferguson's Return Will 'Take Some Time'

The Los Angeles Rams may be without another player, as tight end Terrance Ferguson is a ways from still returning.

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Oct 21 • 11:24 AM EDT • Sports • sports.yahoo.com
SPECIAL REPORT: Tough Business

A string of vacant restaurant buildings shows that many restaurants in the region are struggling — and several are closing By Stefan Yablonski [caption id=attachment_11132 align=alignright width=401] Smokey Bones Bar & Fire Grill on Route 31 in Clay closed its doors in April. It had been in operation since at least 2008.[/caption] By their nature, most restaurants have a limited life. An astonishing 60% go out of business within three years of opening, largely due to fundamental flaws in the planning of the operation. But even restaurants that experience years of success almost always face eventual closure. The restaurant business is very hard and because of both personal factors and external factors beyond anyone’s control, restaurants don’t last forever. For many restaurants, age is a big factor, according to Kenneth Walsleben, professor of practice, entrepreneurship and emerging enterprises at Syracuse University. “The owners have been at it for 20 or 25 years, if not longer, they want some time to themselves,” he said. Such was the case for Jocko’s Famous Ritz Diner in Oswego. Jocko Reitz bought the building in the late 1970s from Robert Shapiro. However, when he stepped away from the business, it eventually closed. [caption id=attachment_11142 align=alignright width=402] For nearly 80 years, Vona’s Restaurant passed through three generations of family in Oswego. It closed its doors on Dec. 31, 2025.[/caption] For nearly 80 years, Vona’s passed through three generations of family in Oswego. Vona’s Restaurant officially closed its doors on Dec. 31, 2025, when no family member wanted to take over. It is on the market. The Ruby Tuesday in Oswego operated for about two decades before permanently closing in April 2026. The restaurant faced multiple temporary health department closures in 2024 and 2025 due to persistent fruit fly and foundation pest issues. Management posted a final closure notice on the doors in mid-April 2026 and the building was put up for sale. The same pattern has been happening in Onondaga County. The big building once used by Smokey Bones Bar & Fire Grill on Route 31 in Clay remains empty, more than six months after the restaurant closed its doors in April. It had been in operation since at least 2008. [caption id=attachment_11130 align=alignright width=401] Ruby Tuesday in Oswego operated for about two decades before permanently closing in April 2026.[/caption] Just down the road from Smokey Bones, the popular Outback Steakhouse closed in August 2024. Another restaurant took its place, La Cocina Mexican Restaurant, but it closed shortly after. The building sits empty. Other very popular restaurants in the northern suburbs of Syracuse have recently closed. Among them, Fireside by the River in Baldwinsville and Primo Nestico’s Bistro Bar in North Syracuse. “I haven’t really paid attention to the Syracuse area. There has always been some turnover, but there probably has never been a tougher time to be a restauranter than now. It’s just brutal,” Walsleben said. In the first year, roughly 20% to 25% of restaurants close or change hands, according to the National Restaurant Association. [caption id=attachment_11122 align=alignright width=401] Outback Steakhouse closed in August 2024. Another restaurant took its place, La Cocina Mexican Restaurant, but it closed shortly after. The building sits empty.[/caption] “Depending on what statistics you look at, you’ll find that any business has a high mortality rate in the first year. That is just the nature of entrepreneurship,” Walsleben said. “There are certain ones that are getting hit hard while others are more fruitful. “And when you look at the restaurant industry you have to factor in labor which is a large part — typically a third of your expenses — and those costs are going up. And there is always turnover which means investing money to train people. Then you’ve got food costs, which is also a third of the typical restaurant budget. Since the pandemic labor has gone up 41%, food costs have gone up 35%. That’s a big tight squeeze righty there. That’s two-thirds of your budget that has gone up 35% to 40% in the last few years. And then the only way you can make that work is to raise the prices.” The National Restaurant Association reports menu prices are up 36% since February of 2020. In a survey released by the association, more than eight in 10 restaurant owners reported that their food, beverage and labor costs are now higher than before the pandemic. You have to deal with the reality of are the customers willing to pay for that? Walsleben added. Restaurants historically have very thin margins; their profit margin is about 5%. “You have a third that goes into food, a third that goes into labor and about 28%, 29% that goes into everything else — overhead, insurance etc. So that brings you down to your 5% leftover,” he said. “Everything is going up. Customer expectations are going up and people aren’t going to spend that much more. So, you have a tight squeeze here,” Walsleben continued. “Restaurants who use delivery apps, they pay a fee to those guys. Those guys don’t work for free. So, you can kind of see where the squeeze comes from.” Stuck in the middle There are pockets of opportunity; the two extremes of the market can make a profit. But the middle gets squeezed out. “If you are a low-end fast-food kind of place, there is room for that. People have changed their budgets. They are still going out, but they are not spending more,” according to Walsleben. “The high end remains positive. If you have a restaurant that brings a specific experience … a great food product or you are catering to high end customers who aren’t so budget conscious, those patrons are going to expect a high-end experience. They expect excellent food every time. They are expecting excellent service. If you can meet those expectations there is room for you at the top. It’s just the guys in the middle are getting the squeeze from both ends. Tough competition, customer expectations, costs are up. Menu items, you can’t raise the prices as much as you need to. That is why you are seeing a lot of restaurants baling out.” The ones that can adapt quickly are the ones who are doing OK. “Success is heavily dependent on the strength of a restaurant’s concept development and the planning of its execution. Eventually things aren’t always new. Things change. So, if you are in the restaurant business you have got to change your menu — keep things new, fresh and update your meals. It is very fickle industry. One year carbs are out, the next year berries are out. Everybody’s diet changes — constantly chasing the latest phase. You have got to adjust your menu and move with those modifications. If you have a static menu that you have used the last couple years that hasn’t changed except for the pricing, you’ve got a problem,” he said. A lot of times these buildings are singular purpose, he added. “You have a commercially viable kitchen and you got a seating area. There is not a lot of other businesses that cater to that type of a layout. So, it’s pretty common to see another restaurant slide in,” he said. One of the things a banker learns early on is you don’t lend money to restaurants … because they fail so quickly. It is very hard to predict who the winners will be. So, if you are a restaurant in addition to all the other challenges, it is very difficult to get loans, according to Walsleben. “You might work really well in the kitchen. But that doesn’t mean you are a great businessperson,” he said. “Restaurants can fail because the owner didn’t know how to manage things properly. There are a lot of challenges. “There is opportunity at the high end and the low end. But in the middle, that’s the death valley. There are just so many things working against you. You really need to have something that will pull people in and continue to pull people in because you to constantly have to change. Think about a theme and a product that is unique to the area people don’t travel that far these days you have to be able to deliver it in an innovative fashion and keep updating to keep people coming in the door.” Out of Business? How Fast? Do nine out of 10 restaurants fail in their first year, as commonly claimed? No. Survival analysis of 1.9 million longitudinal microdata for 81,000 full-service restaurants in a 20-year U.S. Bureau of Labor Statistics non public census of business establishments in the western US shows that only 17% of independently owned full-service restaurant startups failed in their first year, compared with 19% for all other service-providing startups, according to ResearchGate. The median lifespan of restaurants is about 4.5 years, slightly longer than that of other service businesses (4.25 years). However, the median lifespan of a restaurant startup with 5 or fewer employees is 3.75 years, slightly shorter than that of other service businesses of the same startup size (4.0 years). What Makes a Restaurant Successful? Opening and maintaining a successful restaurant is not as easy as creating a great menu and serving excellent food. It takes more than that, according to local restaurant owners who have been in business for decades in the region. They all agree that there are some guidelines to running a successful restaurant. • Quality food: Successful restaurants know exactly what they serve and who they serve it to. Delivering the same great taste every single time builds loyal customers. • Smooth operations: Friendly greetings and attentive staff make guests feel welcome from the moment they walk in. Hiring staff for personality and training for skill ensures reliable, caring service. • Smart marketing: Exceptional food and experiences naturally get people talking and sharing online. Word of mouth can help entice customers. Consistent social media and targeted advertising brings in new and repeat guests also. The menu is what keeps patrons coming back to Mimi’s Diner in Fulton, located at 201 N. Second St. “We locally source our produce and our meats. Our chicken and biscuits is a popular, popular special,” said Richard Tagliareni, the third-generation owner and general manager. “It’s all homemade. We have consistently served quality food.” His grandfather started the business more than 55 years ago. Mimi’s is engrained in the community. They cater to the community and are very involved in everything from the schools to local events. The first Mimi’s Drive-In opened in Mexico. Then a second in Oswego and then Fulton. Fulton’s Mimi’s is the only one left. “The last couple of weeks have been kind of slower than normal. October is usually a busier month for us People will start coming back around again. Also, the price of gas is affecting some things,” Tagliareni added. “We try to keep our prices in line. You go out to eat, you’re going to spend about a hundred bucks or so for two people for dinner. You come here to Mimi’s you are probably for two people for dinner it’s between $50 and $60. We are trying to keep our prices in line. We did have to increase our prices a little bit but things are looking OK.” For the Press Box, 29 E. First St., Oswego, it’s also about great food and a family atmosphere. “Our sports bar and restaurant was established in 1984,” said Alison Canale Scanlon, manager. “I think putting the time into everything makes a big difference and treating people like family when they walk into your restaurant. That’s how we have always operated since 1984.” “It’s the family oriented aspect,” she added. “Consistency, quality and presentation of our food — that’s the secret to a successful restaurant. We try to be very consistent with it. We treat people like family when they come in; because we know how we want to be treated when we go to a restaurant. We treat people the same or better.”

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Oct 14 • 8:23 AM EDT • Business • oswegocountybusiness.com
Tennessee Titans worked out two tight ends on Tuesday

The Tennessee Titans worked out two tight ends as they shuffle their practice squad ahead of the Houston Texans game.

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Oct 7 • 1:20 AM EDT • Sports • sports.yahoo.com
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Political experts call the Georgia governor race 'stuck in molasses'

Republican Rick Jackson holds a tight 49% to 47% lead over Democrat Keisha Lance Bottoms in a new Georgia governor poll.

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Oct 14 • 11:56 PM EDT • Politics • fox5atlanta.com
Eagles to release E.J. Jenkins ahead of Cowboys matchup

The Eagles are releasing E.J. Jenkins, according to Mike Garafolo. The tight end appeared in all six games this season, making two starts

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Oct 22 • 2:36 PM EDT • Sports • sports.yahoo.com
Watchdog seeks tighter oversight of private equity-backed insurers

European insurance regulators have urged EU member states to scrutinize private equity-backed insurers more closely, even before they are authorized to operate, The Royal Gazette reported.

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Oct 8 • 10:12 AM EDT • Business • businessinsurance.com
Mavericks Macao Trip Proves Chemistry Is Already Built

Kyrie Irving and Cooper Flagg are ready. Dallas players say the locker room is tight. The Macao trip shows the Mavericks are set for a run.

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Oct 9 • 9:42 AM EDT • Sports • sports.yahoo.com
CNN’s polling team investigates tightening Senate races in Iowa and Ohio
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Oct 8 • 5:00 AM EDT • Politics • cnn.com
The political stunner of Frank White’s ascension in Arkansas

With the governor's race tightening and Gov. Sarah Sanders making every political mistake in the book, it seems like a good time to revisit the shocking Arkansas governor's race of 1980.

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Oct 14 • 4:21 AM EDT • Politics • arkansasonline.com
Pfizer makes ‘business decision’ to end phase 2 trial of autoimmune drug as program’s future uncertain

Pfizer has called time on a phase 2 trial of its CXCR5 antibody in an autoimmune blood disorder, with the company tight-lipped on whether this marks the end of the road for the asset. The Big Pharma had been evaluating the therapy, dubbed PF-06835375, in a phase 2 study of 61 patients with primary immune thrombocytopenia (ITP) that kicked off in 2022, according to the federal trials register. However, Pfizer confirmed to Fierce on Monday that this study had been terminated “due to a business decision.” “The decision to terminate the trial was not based on any safety concerns,” a spokesperson pointed out. At time of publication, PF-06835375 remained listed on Pfizer’s website for both ITP and lupus. A phase 1 study in lupus wrapped up in 2022, according to the trials database. ITP is an autoimmune disorder characterized by a low platelet count. Novartis was at one point evaluating its B-cell-depleting antibody ianalumab—recently approved as Fabhalta to treat immunoglobulin A nephropathy—as a potential treatment ITP. But the therapy struggled to demonstrate a benefit in the clinic for this indication. When contacted by Fierce, Pfizer wouldn’t confirm whether all work on PF-06835375 has been halted, and whether the company has any other plans to explore C-X-C chemokine receptor type 5 (CXCR5) as a mechanism. CXCR5 is found in blood cancers such as diffuse large B-cell lymphoma and mantle cell lymphoma chemokine receptor. However, there is little expression in normal tissue, which has led some drug developers to explore its potential. Vincerx Pharma had at one point been planning to take an anti-CXCR5 ADC into the clinic to treat B-cell malignancies, but that ambition was scrapped due to cash constraints. Where Big Pharma is placing its bets is one of the hot topics being discussed at Fierce Biotech's high-impact event in London next month. Find out more information and register by clicking on the banner below: [ ](https://qtxasset.com/quartz/qcloud5/media/image/where_big_pharma_is_placing_its_bets.png?VersionId=B8JrRbJ.pFUSK1pJgjeWHLGm_18RdLAy)

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Oct 20 • 3:59 AM EDT • Business • fiercebiotech.com
Broncos select Oregon tight end in 2027 NFL mock draft

The Broncos land Oregon's tight end in this 2027 NFL mock draft.

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Oct 13 • 7:02 AM EDT • Sports • sports.yahoo.com
Trump, Vance to headline three Ohio rallies in 10 days

The campaign stops point to growing GOP anxiety over the tight Senate race between Sen. Jon Husted and former Sen. Sherrod Brown.

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Oct 6 • 5:02 PM EDT • Politics • spectrumnews1.com
Spotify introduces QR code checks for Family plans, missing verification could mean a year-long ban

Spotify is tightening household checks for its Premium Family plan with time-sensitive QR codes, and members who miss the seven-day verification window could face a 12-month restriction on joining another Family plan.

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Oct 19 • 3:04 PM EDT • Technology • firstpost.com
Voters in 12 states face tight races for governor

The Cook Political Report has labeled four governor races as "lean Democrat" and three as "lean Republican."

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Oct 6 • 6:40 PM EDT • Politics • spectrumlocalnews.com
Scientists urge tighter AI controls to prevent global cyber risks
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Oct 13 • 4:00 PM EDT • Science • aljazeera.com
New coalition aims to keep Virginians covered as Medicaid rules tighten

Virginia Secretary of Health and Human Resources Marvin Figueroa on Monday announced the Virginia United Coalition, formalizing a partnership that builds on a series of roundtable meetings with him and Gov. Abigail Spanberger throughout the summer, as well as an executive order she signed.

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Oct 20 • 5:20 AM EDT • Health • virginiamercury.com
Trump to campaign in Ohio, Alaska with Republicans facing tight races

Polls show Republicans at risk as they try to hang on to control of the US Congress for the president's last two years in office.

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Oct 12 • 9:12 AM EDT • Politics • detroitnews.com