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FDA-approved epilepsy drug may help reverse osteoarthritis damage
Researchers at Yale have identified a promising new approach to osteoarthritis that could do more than simply ease pain. The epilepsy drug lacosamide appears to block a protein involved in both pain signaling and cartilage destruction, helping damaged joints shift back toward repair in preclinical studies.
Leucine does more than build muscle. It powers up your cells
The essential amino acid leucine can boost cellular energy production by protecting key proteins on mitochondria from being destroyed. The discovery reveals a new connection between nutrition and metabolism that could eventually lead to new approaches for metabolic disorders and cancer.
Crain’s event: UChicago president talks Chicago’s research-to-business challenge
The program is part of Crain’s Most Innovative Companies event, which will celebrate Chicago businesses that are using technology, strategy and new approaches to gain a competitive edge.
Florida State University doctoral student transforms ‘forever chemicals' research into commercial possibilities through NSF's I-Corps program
A Florida State University doctoral student has developed a new approach to destroying “forever chemicals” and is now taking the technology beyond the
Anthem Draws on Behavioural Science for New “Healthy Influence”
The new approach draws on research into social and behavioural science that focuses on attention, emotion and trust.
When science advances, understanding must keep pace
We are living in an era of extraordinary scientific progress. We can target diseases in ways that were unimaginable a generation ago, develop increasingly sophisticated medicines and explore entirely new approaches to treatment.
Sandhills Community College Small Business Center expands to Moore and Hoke Counties
Small Business Center Director, Laura Kinsman. Photo provided by: SCCSandhills Community College (SCC) is launching a redesigned Small Business Center model that expands no-cost entrepreneurial support across Moore and Hoke Counties. Rooted in the College’s commitment to strengthening small businesses and entrepreneurship as drivers of economic growth, the enhanced model is led by recently appointed Small Business Center Director, Laura Kinsman. The model also includes two new Senior Business Advisors who will provide trusted expertise, stronger community connections, and individualized guidance to entrepreneurs and business owners throughout the region.Kinsman brings a unique perspective to the director’s role as both a local business owner, operating in downtown Southern Pines, and a former Moore County educator. “Her combination of education, business ownership, leadership, and community involvement make her a great fit for the Small Business Center and the work we are continuing to build across Moore and Hoke counties,” said Taylor L. McCaskill, senior director of Workforce Development & Corporate Partnerships in a press release.Kinsman is an active member of the Southern Pines Business Association and has been connected to the Sandhills Small Business Center since the beginning of her entrepreneurial journey. She looks forward to building on that experience by strengthening the Center’s partnerships and expanding its connections throughout the community.She will lead the Center's efforts to support entrepreneurs and business owners throughout Moore and Hoke County and be the connector to the North Carolina Community College System Small Business Center Network operations. The Center offers no-cost, confidential one-on-one counseling, practical workshops, and connections to the resources and partners that help local businesses start, grow, and create jobs.A key part of this new approach, only offered at SCC, is a network of Senior Business Advisors, experienced professionals who will provide individualized guidance in areas such as business planning, finance, marketing, operations, growth strategy, and problem-solving. These advisors will serve as trusted partners to entrepreneurs and business owners, helping them turn ideas into action, overcome barriers, strengthen existing businesses, and pursue new opportunities. This one-on-one counseling is available at no cost, ensuring that high-quality business support is accessible to entrepreneurs at every stage.Senior Business Advisor for Hoke County, Kenna Parks. Photo provided by: SCCKenna Parks has been named the senior business advisor for Hoke County. She is a business professional, entrepreneur, and educator who brings a unique combination of academic training and real-world business experience. She earned her Master of Business Administration (MBA) in 2017 and has built her career around entrepreneurship, marketing, business development, and helping others turn ideas into sustainable opportunities.Senior Business Advisor for Moore County, Katrin Henderson. Photo provided by: SCCAs a military spouse, she has successfully launched and operated businesses across five states, giving her firsthand experience in adapting to diverse markets, building new customer bases and understanding the importance of global reach in today’s business environment. Over the last decade, her areas of focus include business planning, marketing strategy, branding, customer development, financial preparedness, operational planning and connecting entrepreneurs with educational programs and community resources.Parks brings an especially valuable perspective to business advising because she is an entrepreneur herself. She is the owner of Glamo Society Bridal & Formal Wear in Raeford, N.C., giving her firsthand experience with the realities of launching, operating, marketing and growing a small business. She understands that entrepreneurship extends far beyond developing a great idea; it requires strategy, financial awareness, adaptability, strong customer relationships, and consistent execution.Katrin Henderson will serve as the senior business advisor for Moore County. Thriving in hospitality and retail, Henderson has enjoyed positions in Food & Beverage Management and Retail Management in various fine dining and retail establishments in the area, before opening her own children's shop in 2015, in the Village of Pinehurst. She is a native of Moore County.Quickly immersing herself in this new world of small business ownership, Henderson joined various boards and committees, including President Elect of Pinehurst Business Partners and Event Chair for the Holly Arts & Crafts Festival. She also partnered with local organizations such as Moore County Economic Development and Moore County Chamber of Commerce and Sandhills Community College Small Business Center in events and educational opportunities. In 2026, Henderson sold her shop and now offers full-time support to both new and seasoned entrepreneurs through freelance consulting mentorship and the SCC Small Business Center program.The Small Business Center team is passionate about making business resources more accessible, and ensuring entrepreneurs know they do not have to navigate business ownership alone. Through their work with SCC, they are committed to building meaningful relationships with local businesses, community organizations, and industry partners while helping entrepreneurs move from idea to strategy, strategy to action, and action to sustainable growth.“Sandhills Community College believes deeply in the power of small business and entrepreneurship because strong local businesses create jobs, spark innovation, generate investment, and strengthen the communities we serve,” said McCaskill in press release. “Through this new Small Business Center model, Sandhills is building a stronger ecosystem where entrepreneurs can connect, grow, and thrive, while helping drive long-term economic vitality throughout our region.”To learn more about the Center's services or to schedule a consultation, please contact Kinsman directly at kinsmanl@sandhills.edu or 910-695-3938.
Drones, satellites and AI help scientists watch over Antarctica's smallest lifeforms
Monitoring Antarctica's tiny, scattered ecosystems is a challenge that has long plagued researchers. But a new study led by the University of Wollongong (UOW) offers a new approach to tracking life in ...
“Resident Evil” (2026) Review and Film Franchise Retrospective
After years of poorly made adaptations, “Resident Evil” (2026), directed by Zach Cregger, attempts a new approach to a story that fans have witnessed many times. From 2002 to 2017, Sony released six action-horror movies based on the game series. Mostly directed by Paul W. S. Anderson, the films would create new characters and seemed...
LIVE: Six years on from COVID-19, is the world ready for the next pandemic?
COVID-19 killed millions, shattered health systems and brought the global economy to a virtual standstill. World leaders are meeting Friday to review the lessons learned and cement a new approach to prevention and preparation for the next pandemic. Hopes are high that a World Health Organization-led international agreement can move forward.
Holland America continues to raise the bar for cruise ship entertainment with 4 new shows on Oosterdam
Last year's "Fosse and Verdon, The Duet That Changed Broadway" was only the beginning of a whole new approach to onboard productions.
Bangladesh's new approach to noncommunicable diseases
Bangladesh has committed to reducing premature deaths from noncommunicable diseases, rebuilding prevention and control efforts around primary health care.
A Stealth Startup Thinks It Just Hacked the Memory Shortage
Kepler Computing claims a new approach to chip design—and a proprietary material—can help end the supply bottlenecks that have sent memory prices surging.
These Russian Mathematicians Taught AI Models How to Talk to Each Other Without Using Words
A startup called Mostik has a wild new approach to combining the capabilities of AI models.
Bayer's investigational PET tracer shows high accuracy for cardiac amyloidosis
The imaging agent could offer a new approach for diagnosing stiff heart syndrome, according to data presented during the European Society of Cardiology Congress.
The View’s Sunny Hostin Makes Risky AI Move That Could Change Everything
Sunny Hostin is taking a new approach to adapting her writing for the screen. The View co-host has signed a licensing agreement with AI entertainment company Fountain 0, giving the studio access to he...
Measuring ROI For Healthcare AI May Require A New Approach
AI tools in healthcare may add value in novel and non-traditional ways.
Alexander Dupuy’s Approach to Materials Science: Processing Possibilities
UConn materials scientist Alexander Dupuy is exploring how new approaches to materials processing could unlock advances in technologies ranging from solid-s ...
Josh Franco Receives the 2026 APSA Award for Teaching Innovation -
The APSA Award for Teaching Innovation honors a wide range of new directions in teaching by recognizing a political scientist who has developed an effective new approach to teaching in the discipline. Citation from the Award Committee: [...]
Trump halts talks with Iran, signaling a new approach in the nearly 6-month war
For weeks, President Donald Trump has tried willing positive developments with Iran into existence, without much success.
Maine to explore the role of AI in rural health care
The state needs “a new approach to delivering rural health care,” officials said in a proposal for federal funding.
Ozempic may have revealed the brain’s hidden “craving center”
Ozempic-like drugs appear to weaken more than hunger—they may also reduce cravings for alcohol and other addictive substances. Scientists are increasingly tracing this effect to the lateral septum, a brain region that helps connect memories and surroundings with rewarding experiences. Packed with GLP-1 receptors, it may act as a crucial control point between thinking about a reward and feeling compelled to pursue it. The discovery could open new approaches to treating addiction as well as obesity.
Woman’s Perinatal Mental Health Unit leads a new approach to maternal mental health
The Perinatal Mental Health Unit at Woman’s Hospital is being honored with a Community Impact Award for its work establishing mental health care for pregnant and postpartum women. The award is part of Business Report’s inaugural Excellence in Healthcare Awards. The hospital opened the Perinatal Mental Health Unit, Louisiana’s first inpatient psychiatric unit dedicated exclusively […]
Construction's new approach: Protecting margins with risk management
Mid-market construction firms face margin pressure from cost volatility and labor shortages, making proactive risk management key to profitability.
Beyond 'healthy' obesity: New framework weighs organ damage and daily limitations
A new approach to defining obesity could help physicians better determine which patients need more intensive treatment by focusing on the effects of excess adiposity on organs and tissues rather than ...
Hands on science lessons for Independence students
INDEPENDENCE, Ohio – Youngsters in Independence schools have enjoyed a whole new approach to learning science over the past year.
Trump’s $200 Billion Research Reset Funds Scientists, Not University Systems
By removing university bureaucracies from their role as middlemen, this new approach to funding will speed up scientific research.
Wyss Institute receives Massachusetts Life Science Center award to advance metabolomics and lipidomics research across Massachusetts ecosystem
By Benjamin Boettner (BOSTON) — The Wyss Institute at Harvard University has received an award from the Massachusetts Life Science Center (MLSC), enabling it to host a next-generation metabolomics and lipidomics analytical platform. The platform will allow its researchers to creatively pursue new approaches to biomarker and drug discovery across multiple health challenges the Institute...
Are glucose monitors a good thing for 2-year-olds? Experts look at risks, benefits
The newly approved over-the-counter CGM offers a new approach to tackling childhood obesity but also raises a host of questions.
ASU scientists unveil new methods to extract reliable truth from imperfect data
Scientists at Arizona State University are advancing how they interpret complex, imperfect data — challenging long-standing assumptions in fields ranging from imaging to cellular biology. In two papers published in Nature Communications and Proceedings of the National Academy of Sciences, the team introduces fundamentally new approaches to solving “inverse problems,” where researchers work backward from noisy observations to uncover the underlying reality.
Generative AI chest X-ray models offer new approach to radiology reporting and quality improvement
While the technology remains investigational in many practices, researchers say it has the potential to improve diagnostic accuracy, streamline AI development and strengthen radiology quality assurance.
All of Us tests a new approach to collect real-world data for research
The NIH All of Us Research Program has secured thousands of electronic medical records through an innovative use of patient data-sharing networks
SBA’s Proposed Update to the 8(a) Business Development Program: A New Approach to Social Disadvantage
On June 11, 2026, the Small Business Administration (“SBA”) published a proposed rule that would fundamentally alter how individuals qualify as “socially
Healthcare Providers Look Beyond Price To Deliver Better Value
A new approach to procurement promises to not just produce much-needed cost savings but also improve outcomes for patients.
These companies are finding new ways to use AI and tech for security, health, and more
The 2026 AI and technology category for World Changing Ideas is full of new approaches to AI detection, mental health assessment, and even energy.
Two NAU environmental science and policy master’s students receive national conservation scholarships
Northern Arizona University’s School of Earth and Sustainability and the Wyss Foundation have named environmental science and policy graduate students Taylor Hartness and Tia Hatton as 2026-2027 Wyss Conservation Scholars. The prestigious program supports innovative graduate-level education to advance a new generation of leaders in U.S. land conservation. Scholars are chosen for their commitment to conservation and their leadership qualities. They are pursuing interdisciplinary graduate studies to develop effective new approaches to today’s most…
MSI’s New MEG Vision X2 AI+ Desktop Ships With A Talking Holographic Pet That Tweaks Your RGB And Performance On Command
MSI is taking the AI experience to the next level by introducing a live AI agent that helps users in real-time. MSI Unveils MEG Vision X2 AI+ Desktop, Coupled With LuckyClaw That Becomes Personal AI Companion for Making Tasks Easier Artificial Intelligence is no longer limited to chats and image generation. It's now assisting users in real-time, and the new approach just took MSI's newly launched desktop to a new level that might become a common theme in future PCs. MSI has launched MEG Vision X2 AI+, which it calls the "next evolution" in intelligent gaming desktops. Alongside the MEG […]
New depression treatment targets the immune system instead of the brain
A surprising new approach to depression treatment is showing early promise — not by targeting brain chemicals, but by calming the immune system. In a small clinical trial, researchers found that an anti-inflammatory drug normally used for rheumatoid arthritis appeared to ease symptoms in people with hard-to-treat depression, while also reducing fatigue and anxiety and improving quality of life.
Popular weight loss drugs like Wegovy may also target arthritis inflammation
Researchers have discovered that the GLP-1 hormone targeted by drugs like Wegovy is present in very low amounts inside the joints of arthritis patients. That finding suggests high-dose GLP-1 medications could potentially reach the joints and influence inflammation directly, not just help through weight loss. Scientists say this could open the door to a completely new approach to arthritis treatment.
Kids’ mental health - time to close the gap: Marissa Kiefer
Mental and behavioral health challenges among young people are not rare -- they’re part of life for many families. But at UH Rainbow Babies & Children’s, we’re dedicated to trying new approaches, writes guest columnist Marissa Kiefer, president of University Hospitals' Rainbow Babies & Children’s and MacDonald Women’s hospitals.
Strategies for improving women’s health explored at student-led summit | Harvard T.H. Chan School of Public Health
Speakers at the first Women’s Health Student Summit at the School discussed the need for a new approach to women's health.
Tiny ocean life helps scientists estimate whale prevalence off the California coast
A new approach to better assessing whale population data has emerged, led by a research team of marine biologists from Scripps Institution of Oceanography at UC San Diego and statisticians from Cal Poly. ...
Duxbury, Massachusetts wellness clinic explores new approach to maternal mental health: "This is an oasis"
Hope out of chaos: how the dark era of Trump is creating a new approach to global politics
There is cautious optimism that ‘a majority of multilateralists’ may be able to enduringly reshape global alliances
‘We need to take a new approach to break this cycle’
Opinion, comment and editorials of the day
Scientists Say They’ve Tested a Way to Get to Alpha Centauri in Just 20 Years
Scientists say they've come up with a new approach that uses lasers for propulsion, which could cut down the journey to Alpha Centauri.
A new approach to brain health, one neuron at a time
Neuroscientist Paul Nuyujukian likens the brain to a stadium full of people. To eavesdrop on the crowd you could put a microphone in the middle of the stadium. But to understand the conversations you need to record individual people. He thinks about the brain the same way. To understand brain disease, he studies neurons—one at a time. And his insights are shedding light on a big global issue—stroke. The World Health Organization predicts one in four adults will have a stroke in their lifetime. Strokes can cause death, or lead to paralysis or speech problems. But there’s still a lot researchers don’t know about how the brain recovers from an event like a stroke. Nuyujukian directs a lab at Stanford University that studies how the brain controls movement, including after neurological events like stroke. We get into how he does this, and why he hopes his research could eventually help people who’ve been paralyzed. Email us your questions about the brain – or anything else to do with science at shortwave@npr.org. We may turn it into an episode in the future!Listen to every episode of Short Wave sponsor-free and support our work at NPR by signing up for Short Wave+ at plus.npr.org/shortwave.
Safeguarding health care in rural Missouri demands a new approach
Missouri lawmakers are right to treat the collapse of rural health care as an urgent crisis. Nearly half of the state’s remaining rural hospitals are at risk of closure, and many communities already know what it means to lose emergency rooms, labor and delivery services and timely stroke care. In this environment, legislation allowing MU […]
VA Finger Lakes focuses on Whole Health
The VA Finger Lakes healthcare system is taking a new approach to care, which focuses not just on treating illness but healing the whole person.
Melissa Blotter: Advancing the Science of Seizure Intervention
Melissa Blotter is pioneering a bold new approach to treating life-threatening seizures by using ketone bodies to stop them in real time.
Astros New Approach Is Sustainable
For the first couple of games, the Astros offense looked like it was trying to force everything. The swings came early, the contact was weak, and too many innings ended before the opposing starter ever felt uncomfortable. It had that familiar early-season look of a lineup still searching for rhythm. But the last few games […]
Toddler talk: How to criticize adults without destroying them
A 2-year-old’s critique during a car ride leads to a new approach to talks with the next generation.
A 200-year-old light trick just transformed quantum encryption
Scientists have unveiled a new approach to ultra-secure communication that could make quantum encryption simpler and more efficient than ever before. By harnessing a 19th-century optics phenomenon called the Talbot effect, researchers developed a system that sends information using multiple states of single photons instead of just two, dramatically boosting data capacity. Even more impressive, the setup works with standard components and requires only a single detector, reducing cost and complexity.
USC CHIRP Lab program uses barbershops, Fitbits to address health gaps for Black and Latino men
Researchers at the University of South Carolina are testing a new approach to reach Black and Latino men where they already gather, the barbershop, to improve mental health, physical health, and overall well-being.
VoidStealer malware steals Chrome master key via debugger trick
An information stealer called VoidStealer uses a new approach to bypass Chrome's Application-Bound Encryption (ABE) and extract the master key for decrypting sensitive data stored in the browser.
Trump Told Inner Circle Some Mass Deportation Policies Went Too Far
The president is convinced that voters don’t like the term “mass deportation,” and has directed advisers to adopt a new approach on one of his central campaign promises.
Local Spotlight | ArchWell Health Brings a New Approach to Senior Care
Local spotlight is joined by Dr. Doron Schneider, Market Medical Director at ArchWell Health.
Science Lost DEI Programs. Now It Needs Something Better
A new approach that integrates room for debate and collaboration with effective communication strategies can enable more diverse and more effective scientific teams.
Call Of Duty Announces Black Ops Royale, A New Warzone Battle-Royale Mode Inspired By Blackout
We learned about Call of Duty's new approach to the battle royale genre.
Trump tests a new approach in Iran: Regime change without owning the fight
Trump has taken an approach to selling U.S. citizens on military action in Iran that contrasts with his predecessors, seeking to avoid completely owning it.
Nintendo's new approach to amiibo: expensive premium figurines
Nowadays, amiibo cost more than ever, and they don't offer many more in-game bonuses than before. Should Nintendo switch to cards instead?
‘Feeding Tampa Bay’ expands care with new health clinic
A new approach to fighting hunger in the Tampa Bay area is focusing on something bigger than food alone: overall health.
Apple might take a new approach to announcing its next products
Apple has invited the tech press to a “special Apple experience” on March 4, but it might unfold a bit differently than the company's standard press event.
SF: Department Of Public Health Tries New Approaches As City's Overdose Deaths Jump In New Year
The San Francisco Department of Public Health is trying out new strategies to tackle the city's drug crisis after seeing a considerable jump in overdose deaths in January compared to the previous...
Federal government turns to fresher data to rein in Medicare Advantage upcoding
CMS is taking a new approach to limit one of the ways insurers are boosting profits in Medicare Advantage.
‘Everything is quagga mussel now’: can invasive species be stopped?
While ecologists believe invasive species play a major role in more than 60% of plant and animal extinctions, stopping them in their tracks is almost impossible. Biodiversity reporter Phoebe Weston tells Madeleine Finlay how invasive species spread, how conservationists are trying combat them and why some think a radical new approach is needed.
The race to avoid another shutdown: From the Politics Desk
Plus, Tom Homan's new approach in Minneapolis.
A new approach to challenging state abortion bans
And more health news from the Morning Rounds newsletter
A Century of Service: How Jackson County Public Health in Missouri is Leading a New Approach to a Healthy Community
Explore how Jackson County Public Health in Lee’s Summit, Missouri, marks 100 years by leading innovation for lasting public health change.
Here's how 'shared decision making' for childhood vaccines could limit access
Robert F. Kennedy Jr.'s new approach to six shots that were formerly given routinely will introduce new hurdles for getting kids immunized. And it could have a chilling effect on doctors.
In State of the State Address, Armstrong says rural health care challenges in ND demand bold action | North Dakota Office of the Governor
North Dakota’s rural health care challenges demand bold action and new approaches, Gov. Kelly Armstrong said in a State of the State Address as the 69th Legislative Assembly convened in special session to appropriate nearly $200 million in federal funding for a statewide Rural Health Transformation Program.
Tiny doses of THC show big benefits for HIV treatment
A new study suggests that micro-doses of THC could help counter many long-term side effects of HIV treatment without causing intoxication. In animal models, low-dose THC reduced inflammation, improved gut bacteria, boosted serotonin, and lowered harmful cholesterol and bile acids. Surprisingly, it also reduced circulating levels of antiretroviral drugs while maintaining viral suppression, potentially protecting the liver. Scientists say the results point to a promising new approach for managing chronic complications of HIV.
Inside Robert F. Kennedy Jr.’s Public Health Policies
At the start of the new year, Robert F. Kennedy Jr.’s Department of Health and Human Services formally recommended fewer vaccines for American children and offered a new approach to nutrition with a revamped food pyramid. So what does it all mean for public health police in the United States? NBC’s Anne Thompson reports in this week’s Sunday Focus.
Xbox’s Towerborne is switching from a free-to-play game to a paid one
A new approach for Towerborne.
This simple math trick could transform earthquake science
Earthquakes happen daily, sometimes with devastating consequences, yet predicting them remains out of reach. What scientists can do is map the hidden layers beneath the surface that control how strongly the ground shakes. A new approach speeds up complex seismic simulations by a factor of about 1,000, making risk assessments far more practical. While it won’t forecast the next quake, it could help cities better prepare for one.
Scientists find a safer way to make cells burn more calories
Researchers have developed experimental compounds that make cells burn more calories by subtly tweaking how mitochondria produce energy. Older versions of these chemicals were once used for weight loss—but were banned for being deadly. The new approach fine-tunes the effect, allowing cells to burn extra fuel safely. If successful, this could pave the way for new obesity treatments with added health benefits.
She goes to police calls in a Prius. It’s part of a new approach to mental health emergencies
Briana Fair, a mental health clinician with the San Mateo Police Department, received a dozen voicemails from the same distressed caller over a single weekend this month.
With Trump in Power, Democrats Try to Redefine Themselves as Disrupters
Since President Trump’s rise, Democrats have served as defenders of a political system many Americans believe is broken. Now the party is trying a new approach.
She goes to police calls in a Prius. It's part of new approach to mental health emergencies
San Mateo adopted a new approach to mental health 911 calls by pairing police with mental health clinicians. Researchers found that it reduced the number of future mental health emergency calls and involuntary psychiatric holds by roughly 17%.
US Signs New Health Deals With 9 African Countries That Mirror Trump's Priorities
JOHANNESBURG (AP) — The U.S. government has signed health deals with at least nine African countries, part of its new approach to global health funding, with agreements that reflect the Trump administration’s interests and priorities and are geared toward providing less aid and more mutual ...
Inner Balance Brings New Approach to Women’s Hormone Health and Skin Care
With only two products on the market, Inner Balance is offering an alternative to long-standing treatment models in hormone therapy.
Studies focusing on deteriorating neighborhoods, electronic health records, and gun trafficking highlight this month's research roundup
December's Research Roundup highlights a new approach for improving genetic risk prediction using electronic health records, how interstate gun trafficking
Pebble's founder introduces a $75 AI smart ring for recording brief notes with a press of a button
After rebooting the Pebble smartwatch, founder Eric Migicovsky is expanding his company's device lineup with a new smart wearable: an AI-powered smart ring known as Index 01. Named for the finger where the ring is meant to be worn, the new $75 ring is not meant to be a competitor to the always-on, always-listening AI devices, like the AI pendant Friend, but instead offers a way to record quick notes and reminders with a press of a button on the ring's side. AI only comes into play via the open source, speech-to-text, and AI models that run locally on your smartphone, via the open source Pebble mobile app. That is, if the Ring's button is not being pressed, it's not recording. (And this is a press-and-hold gesture, too, which means you can't start the ring's recording and then let go to surreptitiously record a conversation.) You can wear the stainless steel ring while in the shower, washing hands, doing dishes, or in the rain, but you would have to take it off for other water-related activities, like swimming. At launch, it's water-resistant to 1 meter. The ring is also not a fitness tracker or sleep monitor. It doesn't record details about your heart rate or health. And it's not there to be your AI friend. "I'm not trying to build some AI assistant thing," Migicovsky told TechCrunch in an interview. "I build things that solve one main problem, and they solve it really well," he explains. "I think of as external memory for my brain...that's what this is. It's always with you." Plus, the ring has been designed to be highly reliable and privacy-preserving, he says, as all your thoughts are stored on your phone, not in the cloud. There is no subscription. Migicovsky has been wearing the ring for three months now and says he cannot imagine going back to a world where he doesn't always have a memory device with him. "The problem is that, during the day, I get ideas or I remember something, and if I don't write it down that second, I forget it," he says. The ring solves this problem, he adds, without becoming another device you need to charge. "The battery lasts for years," Migicovsky claims. Technically, the ring is said to support roughly 12 to 14 hours of recording. On average, the founder says he uses it 10-20 times per day to record 3-6 second thoughts. At that rate, he'll get about two years of usage. When the ring's battery dies, you can ship it back to the company for recycling. When using Index, you can record up to five minutes of audio, which can be saved to the ring and synced to your phone later. This makes sense for recording briefer, personal thoughts and notes, even when you don't have your phone handy, but it wouldn't work for recording a longer chat, like a presentation, meeting, or in-person interview of some kind. The ring also supports 99+ languages and has a bit of on-device memory, in case you're not in Bluetooth range of your device, where the recording is ultimately saved and transcribed. (The raw audio is retained, too, in case the speech-to-text is garbled due to loud background noise). If you own a Pebble smartwatch or one from another brand, your recorded thought can even appear on the watch's screen so you can verify it's correct. The ring works with Pebble's mobile app, which offers notes and reminders, but can optionally integrate with your phone's calendaring system, too, or other apps, like Notion. And the ring's software is open source, which makes it hackable by the community, the founder points out. Because of its open nature, the ring's button is already programmable. In addition to the press-and-hold gesture, you can program the ring to do other things with a single or double press, like play or pause your music or control the shutter on your phone's camera. You could use it to send a message through the universal chat app Beeper, which Migicovsky also created, or you could add your own voice actions via MCP. A new approach to hardware Migicovsky acknowledges that hardware can be difficult to get right -- as the previous exit of Pebble to Fitbit showed. (Fitbit, too, was later acquired by Google in 2021). "I didn't earn any money during Pebble -- we exited, but it was not a great exit," Migicovsky admits. This year, however, he decided to reboot the Pebble project after Google open sourced the PebbleOS, which opened up the door to new hardware. With his new company, Core Devices, Migicovsky plans to do things differently. Still, the founder doesn't regret his previous choices, he clarifies. "I wouldn't have gone back and changed anything. I loved what we built. I loved what we did. I love the company that we built, but it's not the only way to build a company," he told TechCrunch. " And, speaking as an ex-YC partner, there are -- there's a time and a place for building a venture-backed startup. Some companies are phenomenal when they raise money and build a big team, and I tried that...I think what I'm doing now is trying an alternative path, which is start from profitability," he says. The new company is a small team of five, self-funded, and focused on sustainability. So far, Core Devices has shipped the Pebble 2 Duo smartwatch with a black-and-white display. Its first run sold out, and the company is now preparing to ship the upgraded version, the Pebble Time 2. The newer device, which has seen 25,000 pre-orders, is a stainless steel watch with a larger, color e-ink screen. As for the Index 01, the ring's pre-order offer ends in March 2026. After that, the price increases to $99. It currently comes in silver, polished gold, and matte black and works with iOS and Android devices. Customers can select from eight ring sizes and three colors.
Science history: Female chemist initially barred from research helps helps develop drug for remarkable-but-short-lived recovery in children with leukemia
In December 1954, Gertrude Elion and colleagues described a new compound they had developed that sent children with leukemia into remission. It would guide a new approach to "rational drug design."