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A revolutionary new microscope could reveal the hidden machinery of life
Researchers have developed a revolutionary microscope that uses an incredibly powerful laser to make previously invisible cellular structures easier to see. The technology dramatically improves image clarity, allowing scientists to examine small proteins that conventional electron microscopes struggle to capture. It could eventually reveal how tiny molecular machines interact inside cells, providing an unprecedented look at the hidden workings of life.
Oxford scientists discover how viruses build themselves without a blueprint
Scientists have captured virus-like particles assembling themselves step by step, revealing how a surprisingly simple process of trial and error produces complex structures with remarkable precision. The discovery uncovers a crucial molecular turning point that speeds up assembly and could lead to new ways to disrupt viruses and develop vaccines.
Skipped Lunch? Science Explains Why You're Suddenly Craving Happy Hour
Researchers at Brown University found a molecular link between hunger and alcohol cravings.
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New Richland Lab Could Transform How Scientists Study Microbes and Boost Regional Jobs
The BriefGroundbreaking held Tuesday: PNNL officially began construction on the M2PC lab, a 30,800-square-foot facility funded by the U.S. Department of Energy's Office of Science that will study soil microbes to improve crop productivity and develop new biotechnology applications. The facility will be open to researchers from around the nation and the world.Research timelines could shrink dramatically: The facility's automation and AI capabilities could reduce experiments that currently take six months to just 72 hours, allowing scientists to explore more possibilities faster than ever before.New jobs coming to the Tri-Cities: The project is expected to create positions for automation engineers, AI experts, roboticists, technicians, and skilled craftspeople, with the facility opening in 2029.RICHLAND, Wash. — Pacific Northwest National Laboratory broke ground Tuesday on a first-of-its-kind facility that could accelerate scientific discoveries about the microscopic organisms living in soil—organisms that may hold the key to growing more food and developing new energy technologies.The Microbial Molecular Phenotyping Capability, or M2PC, represents a significant investment in automation and artificial intelligence to speed up research that traditionally takes years to complete. The 30,800-square-foot facility will house more than 100 connected automated instruments designed to study microbes at a pace and scale never before possible.Reshaping Agriculture's FutureThe M2PC facility will not put a new tool directly into a farmer's hands tomorrow morning, but it is actively reshaping the commercial pipeline to solve agriculture's biggest headache with biologicals: inconsistent field performance. For years, PNNL researchers have explored how microbes work and how they might help produce useful materials, advance energy technologies, and address challenges involving critical materials and minerals. But those experiments have been limited by what researchers could accomplish by hand."They can be used to provide nutrients to a plant so that the plant would grow more. So, like increasing your crop productivity, for example," said Douglas Mans, PNNL's Associate Laboratory Director for Integrated Discovery Sciences.PNNL's own research shows soil microbes can help plants access nutrients and withstand drought—benefits that could prove crucial as farmers face growing environmental pressures. The M2PC facility will allow scientists to identify and optimize useful microbes faster than ever before, accelerating the development of biological solutions that actually work consistently in the field.What Makes M2PC UniqueThe Microbial Molecular Phenotyping Capability differs from traditional research labs because it operates as a first-of-its-kind, AI-enabled autonomous laboratory designed to shrink experimental timelines from years down to months or weeks. The M2PC lab will connect more than 100 automated instruments to grow microbes, prepare samples, measure their behavior, and link observations to the molecular processes behind them. Artificial intelligence will help analyze results and guide the next experiments, allowing scientists to explore more questions faster.Deb Gracio, PNNL Director, emphasized the transformative potential during Tuesday's groundbreaking ceremony: "Research that has taken years will become possible in months and hopefully in weeks."That acceleration is already being demonstrated. PNNL's smaller automated lab, called the Anaerobic Microbial Phenotyping Platform or AMP2, completed three experimental cycles in just 72 hours—a process that normally would have taken about six months."That normally would have taken us about six months … and we were able to do that in 72 hours," Mans said.The AMP2 laboratory is not being closed or replaced. Instead, the current 1,800-square-foot laboratory serves as an active prototype and precursor for the much larger M2PC facility. AMP2 will continue operating as a separate lab designed to run anaerobic experiments—those conducted in the absence of oxygen—while M2PC will focus on aerobic research.Broader Applications Beyond AgricultureWhile improving crop productivity is one important application, the M2PC facility is designed to support research into multiple areas critical to national priorities. The lab will advance research into biofuels, manufacturing materials, and energy technologies. It will also help researchers understand how microbes respond to environmental changes and how to design biological systems for biotechnology applications.As a flagship component of the Department of Energy's Genesis Mission, M2PC represents a significant investment in using artificial intelligence and automation to accelerate U.S. scientific discovery. Dorothy Koch, Associate Director of the DOE Office of Science Biological and Environmental Research program, highlighted the facility's importance during the groundbreaking."M2PC will accelerate biological discovery and design," Koch said, noting that the facility is expected to conduct a minimum of 500 strain experiments per week, 100 microbiome experiments per week, and take a million measurements per month.Economic Opportunity for the RegionBeyond the scientific breakthroughs, the M2PC project represents significant economic opportunity for the Tri-Cities region. The facility will require hiring automation engineers, AI experts, technicians skilled in operating robotics, and specialized craftspeople to build and maintain the sophisticated equipment."We're anticipating that type of hiring," Mans said when asked about job creation.PNNL has already begun recruiting talent nationally and internationally for positions related to the smaller AMP2 lab, bringing automation engineers from cities like Boston and San Francisco to work in the region. The M2PC facility is expected to accelerate that trend."This capability won't really exist anywhere else in the world," Mans said, suggesting the facility could become a draw for scientific talent seeking to work on cutting-edge biotechnology research.Timeline and Next StepsThe M2PC facility is expected to open in 2029. Between now and then, construction crews will level and prepare the ground, while the building takes shape. Simultaneously, Ginkgo Bio Works, the automation contractor, will build the facility's automation components off-site so they can be installed as the building is completed.In the interim, PNNL researchers and the broader scientific community will begin planning the first experiments to be conducted in the facility, ensuring research is lined up and ready to begin as soon as the doors open.The groundbreaking ceremony included representatives from the Department of Energy, PNNL leadership, and elected officials at the federal, state, and local levels, underscoring the project's significance to the region and the nation's biotechnology future. News The U.S. Department of Energy Secretary tours Pacific Northwest National Laboratory Dan Hanson, Apple Valley News Now News Beyond DNA: Scientists Explore New Frontiers in Biology Research Dan Hanson, Apple Valley News Now News TRIDEC optimistic that Hanford, PNNL will see funding in national budget Robert Desaulniers News Big picture science: monitoring the Yakima River Basin News PNNL research could shape the future of fighting fentanyl COPYRIGHT 2026 BY APPLE VALLEY NEWS NOW. ALL RIGHTS RESERVED. THIS MATERIAL MAY NOT BE PUBLISHED, BROADCAST, REWRITTEN OR REDISTRIBUTED.
NQPI welcomes Professor Michael Held, strengthening connections between molecular biology and nanoscale materials research
The Nanoscale and Quantum Phenomena Institute (NQPI) at Ohio University welcomes Professor Michael Held as its newest faculty member.
Scientists discover why some people still can’t taste food after COVID-19
Scientists have uncovered a possible explanation for why some people struggle to taste food more than a year after recovering from COVID-19. By examining taste buds from patients with lingering symptoms, researchers discovered molecular abnormalities that weaken the signals responsible for detecting sweet, bitter, and savory flavors.
Combination nucleic acid therapies: towards personalized cancer treatment
Combination strategies enable simultaneous activation and silencing of key target genes to correct molecular pathways in pancreatic cancer.
FSU review shows molecular fingerprints of human impacts on global water systems
A Florida State University-led review shows how ultrahigh-resolution mass spectrometry can help researchers identify the molecular fingerprints of human
Great Women of Science: Ada Yonath, the Nobelist exemplifying perseverance
She was told she was chasing the impossible. She persisted through poverty, skepticism, and 25,000 failed attempts. In the end, Ada Yonath unlocked one of biology’s most elusive structures: the ribosome, transforming our understanding of how antibiotics work and paving the way for drugs that can overcome antibiotic resistance. Her story is not only one of scientific brilliance, but of extraordinary perseverance.
ASBMB 2027 organizers preview science, community and Boston
Amy Palmer of the University of Colorado Boulder and W. Mike Henne of the University of Texas Southwestern Medical Center, co-chairs of ASBMB 2027, explain how this gathering will inspire new ideas and drive progress in molecular life sciences.
Gatton Academy Senior Takes Home Third Award at Regeneron International Science and Engineering Fair
Gatton Academy senior Jiwoo Kim (Model Laboratory School) earned Third Award and a cash prize at the renowned Regeneron International Science and Engineering Fair (ISEF) in the cellular and molecular biology category.
Time capsule: As woodstove season approaches, elucidating the differences in hardwood and softwood
From density to molecular structure, potential firewood offers much to consider.
A photoinduced, FeX3-catalyzed, stereo- and regio-selective halofunctionalization of olefins with MXn via a radical-polar crossover reaction
Communications Chemistry - The classical reaction for the halofunctionalization of olefins involves hazardous and highly toxic molecular halogens. Here, the authors report the FeX3-catalyzed...
Whoops! Scientists Might Have Had the Origin of Animals All Wrong.
Molecular clocks push the dawn of animal life back to a frozen world 800 million years ago.
The Math Singularity Is Here, and Science May Be Next
OpenAI has released an extraordinary body of mathematical work produced by an unreleased frontier model: 722 manuscripts spanning 372 research families across fields including number theory, complexity theory, and mathematical physics. Each result required, on average, the equivalent of roughly three hours of ChatGPT Pro reasoning. A New Era of Discovery We may be witnessing the beginnings of a “math singularity”: a point at which machine-generated discovery accelerates beyond humanity’s ability to independently reproduce, verify, or fully absorb it. If frontier models can generate hundreds of meaningful results in the time it takes a human researcher to investigate one, the constraint will no longer be producing new mathematics. It will be our capacity to validate, interpret, and integrate it. This does not make mathematicians obsolete. It changes their role. They may increasingly serve as guides, critics, and meaning-makers. Increasingly, they will decide which questions matter, determining which results can be trusted, and explaining why they are important. Mathematical insight may become abundant, while human judgment becomes more valuable than ever. Mathematics May Be Only the Beginning Every scientific discipline could eventually experience a similar acceleration. AI systems could generate and test hypotheses, connect findings across specialized fields, and explore possibilities at a scale no human research community could match. In medicine, imagine models identifying overlooked disease mechanisms, designing drugs and clinical trials, personalizing treatments, or discovering cures in months rather than decades. In materials science, AI could help create better batteries and cleaner industrial processes. In climate science, it could accelerate advances in energy, forecasting, and carbon removal. In biology, it could uncover relationships hidden across enormous genomic and molecular datasets. The result would not simply be faster research. It could expand the frontier of what is scientifically possible. The New Bottleneck Scientific discovery, however, is not the same as scientific progress. A medical breakthrough must still survive laboratory testing, clinical trials, regulatory scrutiny, manufacturing constraints, and real-world deployment. As machine-generated ideas multiply, the bottleneck may shift from producing breakthroughs to validating them safely and translating them into practice. We may soon have more hypotheses than laboratories can test, more drugs than clinical trials can evaluate, and more mathematical results than experts can review. That imbalance will require better systems for automated verification, reproducible research, prioritization, peer review, and collaboration between AI and domain experts. The importance of OpenAI’s work is not merely the number of manuscripts produced. It offers a glimpse of a world in which intelligence can explore thousands of intellectual paths in parallel. If ideas cease to be scarce, humanity’s defining challenge will be deciding which are true, which matter, and how to turn them into progress. The math singularity is not the end of human inquiry. It is the beginning of a new kind—one in which machines expand the frontier of knowledge and humans decide where it should lead. Subscribe Share Leave a comment
Nobel Prize in chemistry set to be awarded in Stockholm
Last year, three scientists won the Nobel Prize in chemistry for their development of new molecular structures that can trap vast quantities of gas inside.
Nobel Prize in Chemistry Set to Be Awarded in Stockholm
STOCKHOLM (AP) — The Royal Swedish Academy of Sciences will award the Nobel Prize in chemistry Wednesday in Stockholm. Last year, three scientists won the Nobel Prize in chemistry for their development of new molecular structures that can trap vast quantities of gas inside, laying the groundwork to ...
Windber institute's data tracking system used by scientists far and wide
Developed by a member of the Chan Soon-Shiong Institute of Molecular Medicine at Windber, a system for using data to solve real-world problems caused by cancer is making a mark
Yale School of Medicine On the Science of Childhood Anxiety, Say, Anxiety Disorders Are the Most Common Mental Health Challenges In Youth
Credit: Matt Bradbury October 5, 2026 - By Isabella Backman - Anxiety disorders are the most common mental health challenges in youth. Left untreated, they can disrupt the lives of both children and their families. The good news is that with intervention, most children will overcome these conditions. Across Yale School of Medicine, scientists are working to understand anxiety at every level, from common anxious behaviors to molecular biomarkers in the brain. They are using their findings to develop and disseminate new evidence-based treatments for childhood anxiety. Today, the go-to treatment for childhood anxiety disorders is cognitive behavioral therapy (CBT). This is a form of psychotherapy that teaches children skills for confronting anxious thoughts and helps them practice managing situations that cause anxiety. While it is the gold-standard treatment backed by considerable scientific evidence, up to 50% of children will not see sufficient benefit from CBT alone. Wendy Silverman, PhD, Alfred A. Messer Professor in the Child Study Center, co-directs the Anxiety and Mood Disorders Program alongside Eli Lebowitz, PhD, associate professor in the Child Study Center. One of their main interests is learning how to improve outcomes beyond CBT. “We’re developing cutting-edge, research-based knowledge that can reduce the suffering that anxiety causes children and their families,” says Silverman. Changing parent behavior YSM experts are investigating how to improve CBT outcomes for children by involving the parents. Silverman’s research has uncovered two main components of parent intervention that improve childhood anxiety: not enabling children to completely avoid the things that make them anxious and taking steps to enhance their autonomy. Parents may unintentionally reinforce their child’s anxiety by allowing them to avoid what makes them anxious. They also may unintentionally limit the children’s sense of autonomy by being overly intrusive. “One of the things that we take pride in is that we’ve focused on trying to understand what parents need to do, and to test our ideas and see if changing the parents’ behaviors is enhancing the effects of CBT,” Silverman says. “Our findings thus far suggest that they do." As much as CBT can be helpful, it can also be challenging to get one’s child to do the necessary steps for CBT to work. This is one important reason why Lebowitz created a novel intervention program for parents named Supportive Parenting for Anxious Childhood Emotions (SPACE). Existing intervention programs often teach parents to act as therapists for their child, such as training them on how to practice breathing exercises. “It makes sense, but this doesn’t work very well in practice,” says Lebowitz. “And part of the reason, I think, is that it’s not easy to get your kid to do things, especially if they’re not excited about doing it.” SPACE is unique because it focuses entirely on parent involvement and changing parental behavior—children are not involved in the sessions. For example, parents learn how to use supportive messages that convey confidence that their child can tolerate and manage distress. “It might sound like a parent saying to a child, ‘I get that this is really hard for you, but I know that you can handle it,’” Lebowitz says. The program also works with parents to identify the ways in which they are accommodating anxious behaviors. “We’ll pick one thing that parents are doing that is an accommodation and help them make a detailed plan for how they’re going to change that,” Lebowitz explains. Treating Anxiety in Children and Adolescents Much of the existing research on SPACE has focused on parents of children under age 14. Ongoing studies are now exploring its use with parents of older teens. “Both anxiety and accommodation can interfere with normative developmental shifts during the teen years, including increased autonomy and individuation from parents,” says Rebecca Etkin, PhD, associate research scientist in the Child Study Center. “In this sense, SPACE may be particularly well-suited for anxious teens and their parents. We want to see whether it is effective during this distinct developmental window.” Unfortunately, many families in need of CBT face barriers, including limited availability of services and geographic constraints. One way to improve access is digital interventions. Silverman and her team are developing an evidence-based digitized intervention program for parents that they can access directly from their computer or smart phone. “The work we’re doing will be one of the very few parent interventions that is digitized and importantly tested for effectiveness,” she says. Creating interventions for anxiety-related challenges Silverman and Lebowitz recently received a generous gift to develop and test other interventions that help parents reduce other child anxiety-related behavioral and emotional difficulties, such as restrictive eating and unexplained somatic symptoms. One of these projects in particular focuses on understanding the risks of social media and its potential benefits, including offering a sense of connection. “A lot of research has focused on the idea that social media is harmful and the less of it the better,” says Lebowitz. “But we actually see is that this is not quite right—there are negatives, but there are also positives. So, we’re trying to get a little bit more nuanced of a picture.” The team is working with teens with social anxiety and their parents over an extended period to better understand their social media habits and how their anxiety levels affect engagement with different platforms. The teens will answer questions sent to an app on their phones about mood and social media usage in an effort to capture emotional responses as they unfold. “We hope to develop interventions that can help make the best of social media while protecting against the more problematic effects,” Lebowitz says. The brain’s role in anxiety Researchers are also testing therapies to address anxiety at the neurological and molecular levels. In collaboration with Dylan Gee, PhD, professor of psychology in Yale's Faculty of Arts and Sciences, and Hilary Blumberg, MD, John and Hope Furth Professor of Psychiatric Neuroscience at Yale School of Medicine, Lebowitz and Silverman are using brain imaging to identify changes in a child’s brain before and after parents enroll in SPACE. In one study, children viewed anxiety-inducing images while undergoing magnetic resonance imaging (MRI); the researchers conducted scans with and without the children’s parents nearby. Before SPACE, children’s brains were better able to activate the regulatory circuitry needed to turn off an anxious response when their parents were nearby. But after SPACE, children could activate this circuitry even without the parent around. “As parents work on gradually reducing some of their accommodations, you can see a child get better at regulating their own fear system in the brain,” Lebowitz says. “It’s remarkable.” Research into the molecular underpinnings of anxiety can also inform new childhood anxiety treatments. In a recent study, Lebowitz, Silverman, and Flora Vaccarino, MD, Harris Professor in the Child Study Center, discovered that a protein known as fibroblast growth factor 2 (FGF2) could be protective from the toxic effects of stress. FGF2 levels in children and their parents were linked to the children’s risk of developing anxiety and depression, the study showed. The findings could help explain why some children who are exposed to early life trauma such as poverty or abuse are more prone to developing mental health disorders. And FGF2 could be a target for treatment. “This is very novel because it starts to give a clue to what is the molecular chain that connects those lived experiences to the actual psychological outcomes,” Lebowitz says. New ways to study and treat childhood anxiety Michael Crowley, PhD, associate professor in the Child Study Center, collaborates with Silverman and Lebowitz to study the role that attention plays in development and maintenance of childhood anxiety. There is a large body of research that shows that anxious children, like anxious adults, are prone to focus on threatening stimuli such as angry faces compared with neutral faces. This has led to innovative interventions that involve attention retraining. The idea is that if experts train children to look away from threatening stimuli, it may reduce their anxiety—especially children with social anxiety who are most prone to attend to threats. The researchers have just completed a clinical trial for attention retraining with 10- to 14-year-olds with social anxiety disorders and are currently analyzing the findings. Besides this innovative attention retraining research, as Crowly notes, “I like to design tasks that are engaging to kids,” Crowley says. “My goal is to assess something without the kids knowing what we are assessing.” With this goal in mind, Crowley has created a virtual game, named Boom, to study threat processing in children with anxiety disorders. The game is similar to that of hot potato—the child and three digital players take turns virtually passing a ball to each other’s gloves. At some point, the ball turns into a bomb, and as the bomb lands in each player’s glove, the outline of the glove turns yellow. The goal is to avoid having the bomb go off in your glove. What isn’t obvious is that the game is designed to measure different types of threatening stimuli, both ambiguous and direct. In the game, the direct threat occurs as the bomb is traveling towards your glove. The ambiguous threat is the yellow outlined glove as it is unknown where the bomb will travel next. While children play the game, Crowley’s team measures their brain activity using electroencephalography (EEG). The researchers have discovered that in kids with anxiety, the brain reacts more strongly to ambiguous threats than it does in their peers, but less strongly to direct threats. They believe that the initial abnormally large brain response to not knowing where the bomb is going impairs the brain's ability to properly respond when the threat is actually traveling the child’s way. “The brains of children with anxiety are unable to differentiate between threats you need to do something about and those that are not your problem.” Michael Crowley, PhD, develops innovative games for studying anxiety in children and adolescents.Credit: Matt Bradbury Based on these insights, Crowley hopes to study whether interventions like attention training could restore appropriate threat processing. Crowley’s team is also working on a test called the Balloon Risk Avoidance Task, which evaluates risk-taking and avoidance behaviors. It features a digital balloon that is full of air and about to burst. Kids have six seconds to let air out of the balloon. The more air they let out, the less risk they face that the balloon will pop. But at the same time, the balloon becomes less valuable as it deflates. “The more air you keep in the balloon, the more points you get,” Crowley explains. So far, the researchers have found that when the balloons pop unexpectedly, teens with social anxiety show distinct brain responses. Studying these responses can help psychologists understand the underlying pathways driving the various manifestations of anxiety. The genetics of anxiety When Thomas Fernandez, MD, associate professor in the Child Study Center and of psychiatry, was still in training, there was a lot of excitement about understanding the genetics associated with autism spectrum disorder. Since then, scientists have identified around 250 genes associated with autism. The genetic contribution to anxiety disorders, on the other hand, has historically received less attention. Anxiety is less heritable than autism, but the genetic contribution for anxiety disorders that emerge in childhood may be higher than for anxiety disorders overall. While scientists estimate the heritability of anxiety disorders in general to be around 30% to 50%, some studies suggest higher heritability for certain childhood-onset anxiety presentations. “I saw firsthand how researchers in the field went about finding vulnerability genes for autism,” Fernandez says. “So, we’re using a very similar playbook for childhood anxiety.” “I saw firsthand how researchers in the field went about finding vulnerability genes for autism. So, we’re using a very similar playbook for childhood anxiety.” Thomas Fernandez, MD Associate Professor In the Child Study Center and in Psychiatry Now, Fernandez and Emily Olfson, MD, PhD, assistant professor in the Child Study Center, are studying children and their parents to identify genetic changes that are present in the child but not the parents, known as “de novo mutations.” “All of us have some de novo mutations—maybe about 50 to 100 sprinkled throughout the genome,” Olfson says. “But when they occur within the coding regions of genes, they can be really disruptive.” Previous research shows that people with autism have higher rates of damaging de novo mutations than the general population. In 2022, Olfson, Lebowitz, Silverman, and Fernandez published a study on 68 children and their families that found that children with anxiety had similarly high levels of these mutations. Studying de novo mutations can help point the researchers to where they should be looking for genes associated with anxiety. “The end game is using the genes to steer us toward the right part of biology that we can then target to come up with better treatments,” Fernandez says. Building on those findings, the team is now studying more families to better understand how these de novo mutations, along with other genetic and environmental factors, shape pediatric anxiety disorders. They recently received a National Institutes of Health grant to enroll 750 new families over the next five years. Olfson is the principal investigator, with co-investigators Lebowitz, Fernandez, Silverman, and Shuangge Steven Ma, PhD, department chair and professor of biostatistics at Yale School of Public Health. Neurodevelopment, Risk Genes, and Mental Health Conditions - The Olfson Lab Joel Gelernter, MD, Foundations Fund Professor of Psychiatry, is interested in how different anxiety disorders differ genomically. “We are studying social phobia, panic disorder, and generalized anxiety disorder, working to understand why people differ in their risk to these specific anxiety disorders and evaluating various risk factors,” he says. Gelernter was recently involved in one of the largest studies to date of the genomics underlying anxiety disorder. The study included around 122,000 people with anxiety disorders and around 730,000 without. It found that some genetic differences associated with anxiety were linked to signaling that helps reduce overactivity in the nervous system. Many anxiety medications available today work by targeting this process. “It’s nice when the biology that you get out of a large genome-wide study ratifies things that we already know because that can help increase confidence in further findings from the study,” Gelernter says. Uncovering the neurobiology of psychiatric disorders John Krystal, MD, Robert L. McNeil, Jr. Professor of Translational Research and chair of the Department of Psychiatry, is interested in the neurobiology of psychiatric disorders, including post-traumatic stress disorder (PTSD), of which anxiety is a major symptom. In the late 1980s, Krystal’s team discovered that the drug yohimbine activated symptoms in patients with PTSD. “This was the first time we could link a specific biological mechanism to the symptoms of PTSD,” Krystal says. At the time, he adds, this finding was highly controversial. “A lot of people felt that PTSD was a purely psychological syndrome that didn’t have an underlying biology.” Since then, Krystal has dived deep into understanding the neurobiology of PTSD to learn how to better treat it. His team is evaluating the use of ketamine and psychedelics. These would be among the first treatments to be developed specifically for PTSD. They may also be applicable for other disorders including anxiety disorders, Krystal adds. An important gap in PTSD treatment is the absence of biological tests that inform how to best help patients manage their PTSD symptoms. A doctor doesn’t diagnose cancer based on how they feel. Rather, they use tests of the biology of the cancer to determine the best course of treatment. “And we can’t do that in any psychiatric disorder other than Alzheimer’s disease,” Krystal says. “But now we are building a foundation for this approach to the treatment of anxiety disorders for the first time.” Source: Yale School of Medicine
Scientists Find A Molecular Clue That Could Explain Why Weight Comes Back
Anyone who has lost a lot of weight knows the cruel part can come later. The scale drops, clothes fit again, and the hard work seems to have paid off. Then the pounds begin creeping back, sometimes al...
Animals may have evolved 200 million years earlier than previously thought, new study suggests
After using a technique called molecular clock analysis, researchers have proposed that the origin of animals could be 200 million years earlier than thought.
Advances in Oncology Treatment Are Changing the Way Cancer Is Detected and Treated at Broward Health
Dr. Sajive Aleyas performing the first case with the Ion Endoluminal System. Cancer care is evolving as researchers and physicians gain a deeper understanding of how cancer develops, progresses and responds to treatment. Advances in molecular testing, imaging, minimally invasive procedures and targeted therapies are giving physicians more information to guide decisions and patients access […]
Mahony named Huck Chair in Genomics and AI
Shaun Mahony, professor of biochemistry and molecular biology in the Penn State Eberly College of Science, has been named the Dorothy Foehr Huck and J. Lloyd Huck Chair in Genomics and AI.
Psycho-cardiovascular interaction network links mental health and heart disease
A new review proposes the psycho-cardiovascular interaction network (PCIN), a framework that links psychological and psychiatric factors with cardiovascular health and disease. The review integrates epidemiological evidence, system-level mechanisms, and molecular signaling pathways to explain how depression, anxiety, chronic stress, and other mental health conditions may contribute to cardiovascular disease (CVD), and vice versa. It focuses on five representative pathways—brain-derived neurotr
How Open Science Can Help Researchers Prepare for the Next Pandemic
NVIDIA is collaborating with organizations including Google DeepMind and the European Molecular Biology Laboratory’s European Bioinformatics Institute to release an open dataset of viral protein structures — giving scientists a head start against diseases.
Could comet 3I/ATLAS teach us about life beyond Earth? Scientists say the story's not over yet.
No evidence has been found linking 3I/ATLAS to aliens. But the interstellar object, just the third of its kind to be found, shows that life's molecular precursors are abundant in the Milky Way.
Upcoming opportunities
🔬 Know a scientist whose sustained service to ASBMB and professional accomplishments have advanced the molecular biosciences? Consider nominating them as an ASBMB Fellow.
Scientists reveal how our cells conduct emergency repairs for DNA
Two new federally funded studies offer detailed views of proteins repairing broken DNA inside tightly packed chromatin, and of the molecular toolkit they assemble at a break, with potential implications for cancer treatment
CSU’s biochemistry and molecular biology department hosts annual kickoff
On Monday, Sept. 14, the Colorado State University department of biochemistry and molecular biology hosted its Academic Year Kickoff. The hourlong presentation mainly comprised information about the budgetary system CSU will adopt next fiscal year and the future of the department in response to the change. The event was hosted by department chair Laurie Stargell....
Scientists Discover New Compound That Burns Fat Without Killing Your Appetite
Unlike GLP-1 drugs, which suppress appetite and reduce energy intake, a newly identified molecular compound helps cells burn more energy without changing food intake or exercise and has shown promise in mouse models. The most successful new obesity drugs largely work by helping people eat less. Researchers at UC Berkeley are exploring a different strategy:
MU Health Care earns national recognition by SNMMI
(9/18/26) MU Health Care has been designated a Clinical Radiopharmaceutical Therapy Center of Excellence by the Society of Nuclear Medicine and Molecular Imaging (SNMMI).
Pollard Lecture set for Oct. 8
Dorothee Kern, from Howard Hughes Medical Institute and Scripps Research, will present the 2026 Ernest C. Pollard Lecture in Biochemistry and Molecular Biology, titled “The Protein Dance: From Experiments to AI Predictions,” at 12:10 p.m. on Thursday, Oct. 8, in 008 Mueller Laboratory at Penn State University Park. This free public lecture is sponsored by the Penn State Eberly College of Science.
When DNA sounds a lasting alarm: cGAS-STING links aging to brain inflammation
Neurodegenerative diseases, cerebrovascular disorders and other age-related neurological conditions are major causes of long-term disability. A review published in SCIENCE CHINA Life Sciences by researchers from Huashan Hospital, Fudan University, examines how damaged nuclear DNA and mitochondrial DNA can become immune danger signals. The authors highlight cGAS-STING as a key molecular hub linking cellular damage, inflammaging and neuroimmune dysfunction, and discuss opportunities for more precise therapeutic intervention.
The Science of Childhood Anxiety
Yale researchers are improving the treatment of childhood anxiety by investigating all aspects of the disorder, down to the molecular level.
NSF and UKRI Commit $10 Million in Joint Funding for Molecular Quantum Information Science
The U.S. National Science Foundation (NSF) and UK Research and Innovation (UKRI) have launched a joint $10 million (£7.4 million) research initiative supporting eight transatlantic research teams. Funded via $5 million from the
Chinese scientists develop oil refining method that may cut energy use by 90%
The new process, which works at a molecular level, may also produce higher value end-products, ranging from petrol to plastics.
Scientists discover tiny protein region that shapes tooth enamel
Tooth enamel looks simple from the outside and consists of a hard, smooth surface built to withstand years of wear.
Scientists capture two DNA strands zipping together for the first time
Scientists have directly observed how two negatively charged DNA molecules can pair up despite normally repelling each other. Positively charged metal ions appear to bridge the gap, helping matching DNA helices align groove for groove like a molecular zipper. The discovery confirms a theory proposed two decades ago and could help researchers understand DNA interactions involved in cancer and other cellular processes.
Yourgene Health Insight DPYD assay achieves IVDR accreditation
Yourgene Health (part of the Novacyt Group), an international molecular diagnostics company with a broad portfolio of integrated technologies and services, announces the commercial launch of its In Vitro Diagnostic Regulation (IVDR)-certified Yourgene® Insight DPYD assay, expanding the Company's clinical genetics portfolio across regulated European markets.
Yourgene Health launches Insight DPYD assay (IVDR)
Yourgene Health (part of the Novacyt Group), an international molecular diagnostics company with a broad portfolio of integrated technologies and services, announces the commercial launch of its In Vitro Diagnostic Regulation (IVDR)-certified Yourgene® Insight DPYD assay, expanding the Company's clinical genetics portfolio across regulated European markets.
Upcoming opportunities
🔬 Know a scientist whose sustained service to ASBMB and professional accomplishments have advanced the molecular biosciences? Consider nominating them as an ASBMB Fellow.
UAlbany researchers study how wood smoke affects firefighters at molecular level
At the center of the research is naphthalene, a toxicant found in wood smoke that is produced when wood inside homes and buildings burns.
CSU biology professor delivers talk on extremophilic microorganisms, research advancements
Thomas Santangelo began the department of biology’s fall semester seminar series at Colorado State University strong, presenting the progressive research behind microorganisms in extreme environments and how those observations can inform future research about biological resilience and adaptation. Santangelo, a professor of biochemistry and molecular biology at CSU, was the main speaker of the “Surprises...
Scientists Discover a Hidden Defect That Could Explain Why IBD Keeps Coming Back
A hidden molecular defect in inflammatory bowel disease may help explain why flare-ups can return even when patients appear well. Even when inflammatory bowel disease appears under control, intestinal cells may remain primed to die. In a WEHI-led study, researchers found this hidden molecular defect in patients with few or no symptoms, and higher levels
Prof Elizabeth Streicher unravels the science behind drug-resistant TB
Prof Elizabeth Streicher of the Division of Molecular Biology and Human Genetics delivered her inaugural lecture on Tuesday 1 September 2026. Her research focuses on the transmission and spread of Tuberculosis (TB). Knowing where TB transmission is happening can help to stop it from spreading. Prof Elizabeth Streicher of the Division of Molecular Biology and Human Genetics in the Faculty of Medicine and Health Sciences delivered her inaugural lecture on Tuesday 1 September 2026. The title of her lecture was Decoding tuberculosis: the evolution of technology, epidemiology and the Mycobacterium tuberculosis genome. Streicher explained to Corporate Communication and Marketing how molecular epidemiology (using genetic information to track how and why diseases spread through populations) has improved our understanding of where drug-resistant TB comes from, how it spreads and how drug resistance evolves within and between populations. Tell us more about your research and why you became interested in this specific field. Overall, our research group studies the genome (complete set of DNA instructions found in a cell) of Mycobacterium tuberculosis, the bacteria that cause tuberculosis (TB) disease. Various regions of the genome are interrogated to study different aspects of the disease. My main focus has been on the epidemiology of tuberculosis – how the bacteria’s genome changes over time and what this tells us about the transmission and spread of the disease. How would you describe the relevance of your work? If we understand how the bacteria that cause TB change and spread, it can assist in combating TB globally. How has molecular epidemiology helped improve our understanding of drug-resistant TB? Molecular epidemiology was very important in drug-resistant TB as it was originally believed that bacteria that become resistant to antibiotics would be less fit and not be able to transmit. But it was shown that they can transmit, and therefore have to be monitored to identify hotspots of transmission and outbreaks, etc. Can you tell us briefly about the spoligotyping technique and its advantages for studying drug-resistant TB? Spoligotyping (a molecular technique used to identify and track specific strains of TB bacteria) does not detect drug resistance, but since the technique is relatively quick to do, it can be very useful in real-time situations, e.g. to monitor outbreaks of drug resistance. Why are interrupting transmission chains and identifying genomic hotspots important for controlling the spread of TB? Knowing where TB transmission is happening can assist in allocating resources to those areas to stop future transmission and spread of TB. Higher education can be challenging. What keeps you motivated when things get tough? Students – how they are so passionate and dedicated to learning and contributing to research and society as a whole. What aspects of your work do you enjoy the most? Again, the students and colleagues! But also the fact that it is continuously changing and thereby we are learning and expanding our knowledge. In the end, I know that we contribute to a better society in our small way. Tell us something exciting about yourself that people would not expect. Even though I love hiking (day and multi-day hikes) and being outside, I really do not like camping! How do you spend your free time? I love hiking (wellbeing in nature) and like to watch most sports. ©Higher Education Media Services. Subscribe
KAIST identifies cause of artifacts in battery nanoscale analysis, paving the way for more reliable measurements
- A research team led by Professors Seungbum Hong and Jong Min Yuk from the Department of Materials Science and Engineering and Professor Nam-Soon Choi from the Department of Chemical and Biomolecular Engineering has identified the cause of a measurement artifact in nanoscale battery analysis that can make surface topography appear to represent ion movement. - The team has developed a method to reduce these artificial signals by smoothing rough battery-material surfaces, potentially improving the accuracy of analyses for next-generation batteries, including conventional lithium-ion batteries and emerging technologies such as sodium-ion and solid-state batteries.
Aging doesn't look the same for everyone at the molecular level
People's bodies may reflect their ages very differently at the molecular level, even when they are the same chronological age, according to a new study.
Scientists Capture First Molecular-Level Images of Water Reorganization During a Reaction Crucial for Life
New X-ray approach reveals how charge and surrounding water reorganize during a fundamental chemical reaction
A fifth-grader in Kansas City clicked ball-and-stick atoms together in science class and asked her teacher if she'd made a real molecule — he photographed it, sent it to a chemistry professor, and at ten years old she became co-author of a published paper on a structure nobody had ever described
A ten-year-old's casual question about her chemistry model kit led to a published paper describing a molecular structure that had eluded professional scientists for decades.
Scientists capture first molecular-level images of water reorganization during a reaction crucial for life
Some of nature's most important chemical reactions rely on the coupled movement of negatively and positively charged particles. These processes play central roles in photosynthesis, catalysis and biological ...
The World’s Most Intelligent Octopuses Have A Molecular Quirk That Could Help Explain How Their Brains Increase 100-Fold In Their Lifetimes
Yours, on the other hand, will only quadruple.
The Science of Sex Differences Comes into Focus
From molecular differences in the brain to distinct responses to anesthesia and pain, sex-inclusive research fills gaps left by decades of male-biased studies.
The Concert Pianist Building The Science Of Music Medicine
Concert pianist and molecular biochemist, Dr. Mei Rui, is transforming Music Medicine at MD Anderson.
High-intensity sprints can trigger molecular changes in the bloodstream
A new study finds that an all-out sprint may have unique benefits when it comes to the proteins and tiny molecules in your bloodstream.
Eastlake science students make district history
Three Eastlake High School students made Sweetwater Union High School District history this year when they became the first students from the district to qualify for the International Science and Engineering Fair, an international competition that brings together some of the top high school researchers from around the world. Ronald Wyatt, Giles Del Priore and Ihan Sung advanced to the competition after successful runs at regional and state science fairs. Sung went a step further, placing fourth in the chemistry category at ISEF. The students were recognized on Aug. 10 during a Sweetwater Union High School District board meeting at the district office in Chula Vista.For Wyatt and Del Priore, recent Eastlake graduates, the journey began with a shared concern about dementia and the challenges faced by families caring for loved ones with memory impairment. Their engineering project, “Design and Evaluation of a Behaviorally Grounded Caregiver-Governed AI Companion for Individuals with Memory Impairment,” earned the Sweepstakes Award at the Sweetwater District STEM Fair and first place in its division at the Greater San Diego Science and Engineering Fair. The project explored whether Artificial Intelligence could provide companionship and support while helping reduce stress for people with dementia and their caregivers. “Our inspiration came from personal experience. Both of us have seen family members and loved ones affected by dementia, and we’ve witnessed how overwhelming the caregiving process can be,” Wyatt said. Del Priore said the students also wanted to address the high cost of third-party health care services while creating something that could potentially help their own families as well as people elsewhere. The students developed an AI system designed with safeguards intended to prevent misinformation reinforcement, emotional escalation and unsafe responses. In 240 controlled trials involving memory, identity, agitation and neutral scenarios, they said the system consistently prevented harmful incorrect reinforcement while using context-aware silence, de-escalation and caregiver verification. The project required the students to combine Artificial Intelligence, psychology, neuroscience and human-computer interaction. For Del Priore, one of the biggest technical challenges was getting the AI companion to communicate verbally with a patient. Hardware limitations required the students to collaborate with multiple Python libraries for speech-to-text and text-to-speech functions while keeping the cost of the companion low. “For us, the biggest challenge was translating complex behavioral and cognitive care principles into a functioning AI system,” Wyatt said.Qualifying for ISEF was a milestone that student expected. The international competition proved to be another milestone. “Competing at ISEF was an incredible experience and unlike anything we’ve ever done before,” Del Priore said. “Being surrounded by some of the most talented young researchers from around the world was both inspiring and motivating.” He said the experience stood out because of the emphasis on collaboration, innovation and scientific discovery. “The most memorable part was seeing how people from completely different backgrounds and disciplines approached solving real-world problems with creativity and passion,” he said. The students also credited teachers and mentors who supported their work. Del Priore said his sophomore-year AP Physics teacher, Dr. Price, was particularly influential. “Through all of my personal and academic struggles, Dr. Price always believed in me,” Del Priore said. “All of his faith in me really molded me into the person I am today and helped create my love for science even through tough times.” Wyatt is continuing his education at UC Santa Cruz, where he plans to study biomolecular engineering and bioinformatics, with an interest in research involving Artificial Intelligence, biology and health care. Del Priore plans to double major in chemistry and accounting. Sung, a rising Eastlake senior, qualified for ISEF after winning first place in the Engineering: Energy, Materials & Transport category at the Greater San Diego Science and Engineering Fair and first place in chemistry at the California Science and Engineering Fair. His project, “Renewable Ammonia Electrochemical Synthesis by Glow Discharge with an Iron-Based Catalyst,” involved a device he designed and engineered to produce renewable ammonia, with potential applications in fertilizer production and energy storage. Sung became interested in the project after considering the relationship between food insecurity and fertilizer costs. His system uses plasma to break apart nitrogen molecules so they can interact with hydrogen and form ammonia. At ISEF, Sung competed against more than 1,700 students from 65 countries and earned fourth place in chemistry. “I am proud to become one of te first students in the district to qualify for ISEF because this milestone can inspire others in the district to attain similar goals,” Sung said.
Scientists map hair follicle formation in spacetime, advancing understanding of how organs develop
In a new research report, scientists at Johns Hopkins Medicine say they have developed a technology that allows them to capture a 3D molecular "snapshot" of hundreds of hair follicles as they develop ...
Publication in Science charts a path to democratized molecular innovation
Blocc chemistry is a new way to make medicines, materials and a range of consumer products that is friendly to robots, AI and anyone. An international team of thought leaders has been assembled to prospectively map out how to keep this technology safe and maximize its potential benefits to society.
Mirror cells could threaten life on Earth. Why are we building them?
For people with two hands, one is usually dominant. On a molecular level, earthly life takes this to the extreme. All of the DNA in living things twists to the right, whereas the protein building blocks favor a kind of left-handed chemistry.The rules of life are based on this chemistry.In recent years, scientists have worked toward a kind of mirror version of life. Currently, the technology doesn't exist to make mirror life at the cellular level — and likely won't for at least a decade. Still, a group of scientists is concerned enough about the possibility that they've published a 299-page technical report calling for a stop to the science.In this encore episode for our Tech Camp series, host Regina Barber talks to Carl Zimmer, a science reporter at The New York Times, about his reporting on mirror cells — and why creating them could lead to devastating consequences for life on Earth.Check out Carl's full article.Curious about other controversial research? Email us at shortwave@npr.org.Support public media with NPR+ and enjoy perks for over 25 podcasts like this one. This show’s perks include sponsor-free listening. Learn more at plus.npr.org.
Stanford researchers land NIH grant to advance intraoperative molecular imaging technique
The team is looking to advance the development of a molecular imaging agent that can guide lung cancer surgery in real time.
A mechanically tunable molecular switch for circularly polarized light emission
Over the past few decades, scientists have become increasingly interested in developing materials that do not simply withstand mechanical forces but instead respond to them in useful, detectable ways. ...
Scientists look to shark DNA for the genetic signature of time
Aging leaves telltale marks on DNA, and for the first time, scientists have used those molecular signatures to create a model that predicts the age of sharks.
A tiny molecular basket unlocks a powerful new kind of chemistry
Rice University chemists have found a new way to make neodymium, a rare-earth metal, interact with oxygen. Using a specially designed molecular structure described as a “basket,” the team positioned the atoms so they could form a bond once thought unlikely. The breakthrough produced highly reactive compounds that could eventually give chemists alternatives to iron-based molecules used in biological reactions and chemical manufacturing.
Scientists look to shark DNA for the genetic signature of time
Aging leaves telltale marks on DNA, and for the first time, scientists have used those molecular signatures to create a model that predicts the age of sharks. This tool, known as an epigenetic clock, was developed for the zebra shark (Stegostoma tigrinum) and could soon be expanded to more species,
Scientists repair damaged plastics at the molecular level, boosting recycling potential
Plastic recycling could become far more effective thanks to a new technique that restores the strength of damaged engineering plastics by repairing them at the molecular level.
Scientists cut and rebuild molecules from the inside to create new chiral nanocarbons
Nanocarbons are molecular-scale carbon structures considered to be the building blocks for next-generation materials. Until now, scientists have built them by fusing small, flat carbon molecules together ...
Scientists decipher how T cells sense enemies—such as cancer—at point of contact
Every encounter between a T cell and a potential target—especially when that target is a developing tumor—begins with a rapid series of molecular decisions. Within seconds, the immune cell must determine ...
NIH Renews Prestigious Training Grant for NC State Ph.D. Students Preparing to Lead Complex Research Teams
The National Institutes of Health has approved a $2.5 million grant for the NC State College of Veterinary Medicine to continue the work of its Comparative Molecular Medicine Training Program, which awards fellowships to Ph.D. students in NC State University’s Comparative Medicine Institute. Since NIH first funded the program in 2021, more than 20 students…
RIBER: FIRST-HALF 2026 BUSINESS ACTIVITY Business growth, resilient order book and continued rollout of ROSIE
FIRST-HALF 2026 BUSINESS ACTIVITYBusiness growth, resilient order book and continued rollout of ROSIE Bezons, July 22, 2026 – 8:00 am – RIBER, the global leader in molecular beam epitaxy (MBE) equipment for the semiconductor industry, reported 19% revenue growth for the first half of 2026, supported by strong momentum in services and accessories. Against a commercial backdrop marked by tighter export licensing conditions for Asia, the Company is continuing to roll out its ROSIE strategic roadmap
Researchers gather at Cornell Tech to explore AI for molecular science
Researchers from around the world gathered at Cornell Tech for a workshop exploring how physics-aware artificial intelligence can accelerate the discovery of molecules and materials while improving the reliability of machine learning models.
Scientists spot sugar in interstellar space for the first time ever
Erythrulose—a sugar found in raspberries—is also prevalent in a giant molecular cloud close to our galaxy’s core, scientists have discovered
A family dinner led two Israeli scientists to a clue about life’s origins
A joint study by Prof. Michal Sharon of the Weizmann Institute and her brother Prof. Yossi Paltiel of the Hebrew University suggests magnetism may have influenced two chemical 'fingerprints' of life: molecular chirality and isotope ratios
Protein lactylation in health and diseases: molecular mechanisms, biological significance, and clinical implications
Signal Transduction and Targeted Therapy - Protein lactylation in health and diseases: molecular mechanisms, biological significance, and clinical implications
Building connections across molecular life science
ASBMB President Ed Eisenstein reflects on how the society shaped his scientific career and outlines his vision for expanding connections across academia, industry and government to accelerate discovery, translation and community-building.
Anthropic's New AI Workbench Mapped My Field For $26. Now Imagine It Aimed At The Rest Of Science
Anthropic's Claude Science is a capable AI research workbench built for molecular biology. The opportunities for the rest of science are enormous.
Molecular imaging pioneer Eva Nogales awarded the 2026 Vanderbilt Prize in Biomedical Science
The Vanderbilt Prize in Biomedical Science recognizes scientists who have a stellar record of research accomplishments.
New Molecular Monitoring Offers Scientists a ‘Live Video’ Look at Cells
‘This approach allows us to collect molecular information from precise locations while minimizing disruption to the tissue, making it possible to monitor bi ...
Scientists find molecular-level evidence for two structures in liquid water
A study published in Nature Physics provides new molecular-level evidence from simulations that liquid water is not a single uniform substance, but a constantly shifting mixture of two distinct microscopic ...
NASA rover finds record-breaking trove of complex organic molecules on Mars
Data from NASA’s Perseverance rover confirms the presence of macromolecular carbon on Mars – another potential piece of the puzzle in the search for life.
Scientists observe water switching between 2 different molecular structures, boosting decades-old theory
For decades, scientists suspected water secretly behaves like two different liquids. A new AI-powered study has finally caught it happening at the molecular level.
Water might secretly be a mix of 2 different liquids, scientists say
For decades, scientists suspected water secretly behaves like two different liquids. A new AI-powered study has finally caught it happening at the molecular level.
This DNA repair gene went rogue and exposed a cancer weakness
Scientists have discovered that a gene normally considered a DNA-protecting "good guy" can become dangerous when cells make too much of it. The gene, EXO1, acts like molecular scissors that help repair DNA, but when overproduced it starts cutting DNA it shouldn't, creating damage linked to cancer.
Breakthrough Science Meets Market Skepticism: Insight Molecular Diagnostics Inc. (IMDX)’s Defining Moment
Insight Molecular Diagnostics Inc. (NASDAQ:IMDX) is one of the high-growth micro-cap stocks to buy now. On June 11, Insight Molecular Diagnostics Inc. (NASDAQ:IMDX) announced the online publication in the American Journal of Transplantation of new data demonstrating the statistical superiority of its flagship GraftAssure transplant rejection monitoring assay. The study showed that the novel GraftAssure […]
Watching water nanodrops spread themselves thin
Researchers at the Institute of Industrial Science, The University of Tokyo, have determined the molecular origin of line tension for a water nanodroplet on a surface. This tension is the force along the droplet edge where liquid, solid, and gas phases meet. Computational studies showed that at complete wetting, collapse of tetrahedral order in liquid water causes the line tension to change sign. An ice bilayer did not wet a hydrophilic surface, showing that local order can outweigh surface chemistry.
Commission to examine how precision approaches improve healthcare effectiveness, cost-efficiency, equity, and scalability worldwide.
Prof. Michèle Ramsay at the Sydney Brenner Institute for Molecular Bioscience is one of four co-chairs of the Lancet Commission on Precision Health.
Meet the Researcher: Jianbin Ruan, UConn Health
Jianbin Ruan's lab studies how our immune system works at the molecular level, paving the way for better treatments
Mylpf protein serves as a molecular linchpin for muscle health
University of Maine researchers have published new findings about how muscles form, why certain muscle diseases develop and why symptoms may not appear until years after muscle degeneration begins.
UMaine researchers identify a molecular linchpin for muscle health
Jared Talbot University of Maine researchers have published new findings about how muscles form, why certain muscle diseases develop and why symptoms may not appear until years after muscle degeneration begins. The study, published in Nature Communications, focuses on a protein called Mylpf that is essential for the development of…
Tracking malaria in Central America | Harvard T.H. Chan School of Public Health
Paulo Manrique, PhD ’26, is making novel discoveries about the transmission of malaria in Central America, helping the region’s health ministries develop molecular surveillance capacity to monitor and combat the disease.
A molecular path toward DNA health
UIC researchers identified a molecular pathway that supports healthy aging and cancer prevention.
Four researchers win data harmonization competition
The U.S. National Science Foundation National Synthesis Center for Emergence in the Molecular and Cellular Sciences (NCEMS) at Penn State has awarded four researchers from across the world for their efforts in a competition to build machine learning-based approaches for streamlining publicly available datasets for reuse.
‘Molecular movie’ technology reveals a better way to thwart environmental pollutant
CORVALLIS, Ore. – The latest production from the “molecular movie” imaging technology developed at Oregon State University is a new, inexpensive way of dealing with a common environmental pollutant. Based on short-pulse lasers, the imaging technology allows chemical and biological actions to be measured as they are occurring, one high-speed frame at a time. The measurements occur on the level of the femtosecond – one-millionth of one-billionth of a second. A femtosecond is to a second roughly as a second is to 32 million years.
Richard E. Carson, Ph.D., receives SNMMI 2026 Paul C. Aebersold Award for Outstanding Achievement in Basic Nuclear Medicine Science
Richard E. Carson, PhD, has been named the 2026 recipient of the prestigious Paul C. Aebersold Award. Carson is professor of Biomedical Engineering and of Radiology and Biomedical Imaging at Yale University in New Haven, Connecticut, as well as emeritus director of the Yale PET Center. The award was announced by the Society of Nuclear Medicine and Molecular Imaging (SNMMI) during its 2026 Annual Meeting.
Scientists found the hidden switch fueling alzheimer’s brain inflammation
Scientists at Scripps Research have uncovered a molecular “switch” that appears to fuel the damaging brain inflammation seen in Alzheimer’s disease. They found that a protein called STING becomes chemically altered in a way that keeps the brain’s immune system stuck in overdrive, harming the connections between nerve cells.
World Health Assembly endorses resolution on precision medicine
At the Seventy-ninth World Health Assembly, Member States endorsed a new resolution on Precision medicine: a path towards targeted, personalized and equitable care, taking an important step towards advancing precision medicine as part of efforts to strengthen equitable, effective and sustainable health systems. Precision medicine refers to the use of clinical, molecular, genomic and other health data to inform prevention, diagnosis and treatment, taking into account variability while applying appropriate ethical and legal safeguards. When integrated responsibly into health systems, precision approaches can improve outcomes across different disease areas and across the life course – from cancer and rare diseases to infectious diseases, maternal, newborn and child health, mental health and noncommunicable diseases. The resolution reflects rapid advances in genomics, diagnostics, data science and digital health, alongside widening global inequities in access to these innovations. Many populations – particularly in low- and middle-income countries – remain underrepresented in data and research, limiting the public health impact of precision medicine and risking the widening of health disparities if action is not taken now. "Precision medicine is not an aspirational idea for health delivery in the future – it is already transforming lives across the world. But its benefits remain out of reach for too many and the research driving progress is concentrated in high income countries. This WHA resolution gives global health leaders, ministries of health, and WHO a clear mandate: to act. From infant screening to setting up genomic databases WHO will work with countries to bring about the power of these innovations." Dr Meg Doherty, Director Science for HealthThrough the resolution, Member States commit to developing and strengthening national policies, infrastructure, workforce capacity and governance frameworks to support the safe, ethical and equitable integration of precision medicine into health systems, aligned with universal health coverage. This includes promoting affordability, ensuring inclusive research and data systems, strengthening regulation and data governance, and fostering collaboration across sectors and regions.WHO is requested to provide technical and normative support, review and coordinate existing guidance, facilitate global and regional collaboration, and develop a Global Strategy on Precision Medicine to guide equitable and context‑appropriate implementation. WHO stands ready to support Member States through tools such as a country maturity model for countries to self-assess capacity in implementing precision medicine depending on their context. In the immediate term WHO will map all existing guidance and frameworks and host extensive consultations with interest holders globally.By placing equity, inclusion and public value at the centre of precision medicine, the resolution reinforces WHO’s commitment to ensuring that scientific advances benefit all people, everywhere, and that no one is left behind in the next era of health innovation."By uniting people-centered healthcare with innovation, precision medicine has the potential to transform lives. This resolution helps ensure those advances serve the shared goal of health for all." Dr Sylvie Briand, Chief Scientist For further information please visit the Health Topic: Genomics
The Science Behind the Quest for a Non-Peptide Oral Weight Loss Drug
Not only does it have a tongue-twisting name, “orforglipron” has a complex molecular structure that made its synthesis very challenging. A massive effort by chemists at the Eli Lilly pharmaceutical
Scientists Identify Atomic Trick That Keeps Gold Shiny
Gold’s characteristic glow famously doesn’t fade for thousands of years—and scientists have finally found the molecular trick that makes it so.
Omar Farha Receives Inaugural Reticular Science Prize
The honor is for major advances in the design, discovery, and application of molecularly defined materials.
Barcelona Institute for Global Health: Expanded TB screening does not speed up treatment initiation or improve survival in hospitalised patients with HIV
Adding molecular tests on sputum, urine and stool samples does not appear to outperform the standard WHO-recommended diagnostic approach.