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New Richland Lab Could Transform How Scientists Study Microbes and Boost Regional Jobs
The BriefGroundbreaking held Tuesday: PNNL officially began construction on the M2PC lab, a 30,800-square-foot facility funded by the U.S. Department of Energy's Office of Science that will study soil microbes to improve crop productivity and develop new biotechnology applications. The facility will be open to researchers from around the nation and the world.Research timelines could shrink dramatically: The facility's automation and AI capabilities could reduce experiments that currently take six months to just 72 hours, allowing scientists to explore more possibilities faster than ever before.New jobs coming to the Tri-Cities: The project is expected to create positions for automation engineers, AI experts, roboticists, technicians, and skilled craftspeople, with the facility opening in 2029.RICHLAND, Wash. — Pacific Northwest National Laboratory broke ground Tuesday on a first-of-its-kind facility that could accelerate scientific discoveries about the microscopic organisms living in soil—organisms that may hold the key to growing more food and developing new energy technologies.The Microbial Molecular Phenotyping Capability, or M2PC, represents a significant investment in automation and artificial intelligence to speed up research that traditionally takes years to complete. The 30,800-square-foot facility will house more than 100 connected automated instruments designed to study microbes at a pace and scale never before possible.Reshaping Agriculture's FutureThe M2PC facility will not put a new tool directly into a farmer's hands tomorrow morning, but it is actively reshaping the commercial pipeline to solve agriculture's biggest headache with biologicals: inconsistent field performance. For years, PNNL researchers have explored how microbes work and how they might help produce useful materials, advance energy technologies, and address challenges involving critical materials and minerals. But those experiments have been limited by what researchers could accomplish by hand."They can be used to provide nutrients to a plant so that the plant would grow more. So, like increasing your crop productivity, for example," said Douglas Mans, PNNL's Associate Laboratory Director for Integrated Discovery Sciences.PNNL's own research shows soil microbes can help plants access nutrients and withstand drought—benefits that could prove crucial as farmers face growing environmental pressures. The M2PC facility will allow scientists to identify and optimize useful microbes faster than ever before, accelerating the development of biological solutions that actually work consistently in the field.What Makes M2PC UniqueThe Microbial Molecular Phenotyping Capability differs from traditional research labs because it operates as a first-of-its-kind, AI-enabled autonomous laboratory designed to shrink experimental timelines from years down to months or weeks. The M2PC lab will connect more than 100 automated instruments to grow microbes, prepare samples, measure their behavior, and link observations to the molecular processes behind them. Artificial intelligence will help analyze results and guide the next experiments, allowing scientists to explore more questions faster.Deb Gracio, PNNL Director, emphasized the transformative potential during Tuesday's groundbreaking ceremony: "Research that has taken years will become possible in months and hopefully in weeks."That acceleration is already being demonstrated. PNNL's smaller automated lab, called the Anaerobic Microbial Phenotyping Platform or AMP2, completed three experimental cycles in just 72 hours—a process that normally would have taken about six months."That normally would have taken us about six months … and we were able to do that in 72 hours," Mans said.The AMP2 laboratory is not being closed or replaced. Instead, the current 1,800-square-foot laboratory serves as an active prototype and precursor for the much larger M2PC facility. AMP2 will continue operating as a separate lab designed to run anaerobic experiments—those conducted in the absence of oxygen—while M2PC will focus on aerobic research.Broader Applications Beyond AgricultureWhile improving crop productivity is one important application, the M2PC facility is designed to support research into multiple areas critical to national priorities. The lab will advance research into biofuels, manufacturing materials, and energy technologies. It will also help researchers understand how microbes respond to environmental changes and how to design biological systems for biotechnology applications.As a flagship component of the Department of Energy's Genesis Mission, M2PC represents a significant investment in using artificial intelligence and automation to accelerate U.S. scientific discovery. Dorothy Koch, Associate Director of the DOE Office of Science Biological and Environmental Research program, highlighted the facility's importance during the groundbreaking."M2PC will accelerate biological discovery and design," Koch said, noting that the facility is expected to conduct a minimum of 500 strain experiments per week, 100 microbiome experiments per week, and take a million measurements per month.Economic Opportunity for the RegionBeyond the scientific breakthroughs, the M2PC project represents significant economic opportunity for the Tri-Cities region. The facility will require hiring automation engineers, AI experts, technicians skilled in operating robotics, and specialized craftspeople to build and maintain the sophisticated equipment."We're anticipating that type of hiring," Mans said when asked about job creation.PNNL has already begun recruiting talent nationally and internationally for positions related to the smaller AMP2 lab, bringing automation engineers from cities like Boston and San Francisco to work in the region. The M2PC facility is expected to accelerate that trend."This capability won't really exist anywhere else in the world," Mans said, suggesting the facility could become a draw for scientific talent seeking to work on cutting-edge biotechnology research.Timeline and Next StepsThe M2PC facility is expected to open in 2029. Between now and then, construction crews will level and prepare the ground, while the building takes shape. Simultaneously, Ginkgo Bio Works, the automation contractor, will build the facility's automation components off-site so they can be installed as the building is completed.In the interim, PNNL researchers and the broader scientific community will begin planning the first experiments to be conducted in the facility, ensuring research is lined up and ready to begin as soon as the doors open.The groundbreaking ceremony included representatives from the Department of Energy, PNNL leadership, and elected officials at the federal, state, and local levels, underscoring the project's significance to the region and the nation's biotechnology future. News The U.S. Department of Energy Secretary tours Pacific Northwest National Laboratory Dan Hanson, Apple Valley News Now News Beyond DNA: Scientists Explore New Frontiers in Biology Research Dan Hanson, Apple Valley News Now News TRIDEC optimistic that Hanford, PNNL will see funding in national budget Robert Desaulniers News Big picture science: monitoring the Yakima River Basin News PNNL research could shape the future of fighting fentanyl COPYRIGHT 2026 BY APPLE VALLEY NEWS NOW. ALL RIGHTS RESERVED. THIS MATERIAL MAY NOT BE PUBLISHED, BROADCAST, REWRITTEN OR REDISTRIBUTED.
Does your gut health predict a vaccine fever?
New research suggests your gut microbiome may influence whether you develop a fever after receiving a vaccination.
Gut Microbiome and Aging: How Gut Bacteria Influence Health and Longevity
The gut microbiome changes with age, with microbial diversity and function varying according to health status, diet, lifestyle, and medication use. These changes are associated with inflammation and age-related diseases, but evidence that microbiome-targeted interventions extend human lifespan remains limited.
A Good Gut Feeling Starts with Strong Science
Digestive health is evolving beyond basic gut support as consumers increasingly connect the microbiome to broader wellness goals
Gut health may affect more than digestion, doctor says
A diverse gut microbiome can influence digestion, immune function and the body’s communication with the brain, pathologist Dr. Ryan Cole said in an interview with The National News Desk.
Gut microbiome myths: What science says
Explore gut microbiome myths, probiotics, testing and diet with a Mayo Clinic expert, and learn science-backed ways to support your gut health every day.
Eye Microbiome: How Bacteria May Influence Eye Health and Disease
The ocular surface hosts a low-abundance microbial community that may help regulate immune defenses, while changes in its composition have been associated with inflammatory and infectious eye diseases. Research into the gut-eye axis and microbiome-targeted therapies suggests possible diagnostic and treatment applications, but the underlying mechanisms, causal relationships, and clinical effectiveness remain uncertain.
Was the Human Gut Healthier in Ancient Times?
The microbiome isn’t what it used to be in many parts of the world. The shift may be affecting the well-being of people in industrialized countries.
Nexira spotlights menstrual health ingredient BloomEase and ViNitrox vascular data at SupplySide Global
New clinical findings show ViNitrox improves Flow-Mediated Dilation by 41% versus placebo — while Nexira enters the longevity segment with NU4LIFE and VinOgrape Plus targeting mitochondrial and microbiome health
Inspired By My Love Of STEM, I Collaborated With 22 Teens To Write A Kids Picture Book About Science
Teen STEM student Eliana Miao wrote a picture book about the microbiome and empathy titled "The Brave Fuzzy: A Microbiome Story"
Digbi Health Study of Nearly 16,000 Members Finds Precision Biology GI Care Delivers IBS Relief at Scale
Combining Gut microbiome, genetic, and glucose signals delivers unprecedented personalized care to bring clinically meaningful relief to more than half of symptomatic membersMOUNTAIN VIEW, Calif., Oct. 05, 2026 (GLOBE NEWSWIRE) -- Digbi Health today released a real-world study of nearly 16,000 members of its precision biology program, which personalizes nutrition and lifestyle care to each person's gut microbiome, genetics, and glucose response. Among members followed for 12 weeks, i more than h
‘They misunderstand science’: Research attempting to tie autism to changes in the gut microbiome comes under fire
besity, liver disease, diabetes, and cancer are all chronic diseases that inflict misery across millions of patients. Imagine if bacteria could be to
How your gut microbiome may affect your health
Researcher and dietitian Karen Corbin explains how the trillions of microbes in your gut may influence health and how simple food swaps can increase fiber intake.
The Oral Microbiome Trend Is Going Mainstream and the Science Behind It Is Compelling
Prebiotic toothpastes and microbiome rinses are going mainstream and dentists say the science backs them up.
Microbiome testing company Tiny Health clinches $33M to scale research, enterprise partnerships
Tiny Health, a microbiome testing company, has clinched $33 million in an oversubscribed series B round. | Alongside the funding news, Tiny announced the launch of a $5 million Microbiome Research Program to enable researchers, clinicians and scientific partners to investigate important intervention strategies in microbiome health.
Slashing sugar intake before antibiotics may save your microbiome
Antibiotics can reduce the diversity of microbes in your gut microbiome and lead to health problems, but a study in people with cancer has identified a potential solution
Discover the latest science on probiotics for healthy ageing: From longevity to quality of life
As healthy aging shifts from longevity to quality of life, new research highlights the gut microbiome as a key lever for supporting mobility, muscle function and independence in aging populations
Tiny Health Raises $33M To Explore What Gut Data Can Reveal About Future Health
Austin-based Tiny Health has raised $33 million in a Series B funding round led by B Capital to help it meet growing demand for its at-home microbiome tests.
What your “Gut Feeling” is telling you about your health
Your gut microbiome is made of trillions of microbes such as bacteria, viruses, yeast, and fungi. In the past 10 to 15 years researchers have made big breakthroughs on how
Dirty hands, healthy life? What science really says may shock you - Futura-Sciences
The Rich Ecosystem Right at Our Fingertips For years, our skin was viewed as just a protective barrier. But in truth, it’s an ecosystem bursting with millions of invisible microorganisms: the cutaneous microbiome. It’s home to beneficial bacteria (like Staphylococcus epidermidis and Cutibacterium acnes), fungi (think Malassezia), viruses (such as...
Seventy Years of Microbiome Science in China Signals a One Health Future
Trillions of microorganisms live on and inside the human body, in the soil that grows our food, and in the rivers, oceans and air that surround us. While microbes are most often discussed in the context of infection and disease, the vast majority of these organisms are neither
Hands-on science can be cool
After spending many long days conducting experiments to find a new way to combat bacterial infections in crops, Misha Hegde and Mia Soleil Maurer have been rewarded with international recognition and access to top research facilities. But these are not typical scientists. They are 16-year-old German high school students.“Our supervisor told us that in order to start a project, you need to begin with either a question or a problem,” says Misha, adding that she and Mia had read about antibiotic resistance in certain plants being treated for bacterial infections. “We found out that antibiotics overuse is very common in agriculture,” explains Mia. “Our aim was to create an alternative to antibiotics and to try to raise awareness of the problem of overusing antibiotics.”Their subsequent research has focused on harnessing bacteriophages, the natural predators of bacteria, to eliminate pathogens threatening food crops treated with antibiotics. At the Schuldorf Bergstraße Jugend forscht MakerLab in Seeheim-Jugenheim, located in the German state of Hesse, they discovered a novel phage that infects the Rhizobium rhizogenes bacterium, which causes the hairy root disease that can reduce yields of tomatoes, carrots, soya beans and other food staples.The students believe their method could curb antibiotic use, while protecting plants from infections without disturbing the natural soil microbiome. “The application of phages is host-specific, so they would only kill the targeted pathogen or disease-causing bacteria,” explains Mia. It may also offer environmental benefits, since applying antibiotics can contaminate groundwater.Getting to this point has not been easy. The childhood friends admit to feeling frustrated when their trials did not yield the expected results. “We spent six months on our first experiment, just doing the same thing over and over and over again, to the point where we thought, is it even worth it? Why are we doing this?” Misha says. “You just need to be brave enough to take that first step and keep going.”The benefits of inquiry-based learningTheir determination has paid off. In 2025, the pair won first prize in biology at Jugend forscht, Germany’s national competition for young people interested in science, technology, engineering and mathematics. They were also among the winners of the German Research Foundation Europa-Preis, which is awarded to selected national winners at Jugend forscht, and took third place in the 2025 European Union Contest for Young Scientists.The Jugend forscht Foundation opens doors for young people to connect with scientists as well as industry professionals. Jessica Bönsch, executive director of the Foundation, sees Misha and Mia as prime examples of how young people can develop a deeper understanding of science through their own research projects. “The experience of working on your own research question is very important,” she explains, adding that “inquiry-based learning engages with real-life problems in a way that can be more motivating than traditional classroom teaching.”The Jugend forscht Foundation offers financial support through sponsor pools in Germany’s federal states. Some projects are developed in cooperation with student research centres, university labs or informal collaborative learning areas called makerspaces. Other activities start as hands-on “garage projects” and can grow within the Jugend forscht network and infrastructure.The Jugend forscht Foundation is also a partner of Science Comes to Town, an EU initiative to strengthen public awareness about science and create bridges between researchers and communities. The EU-financed project involves universities, research institutions and other stakeholders in three host cities — Brest (France), Kiel (Germany) and Split (Croatia).“It's so important for people not to live in a bubble, because I think science can be very scary if you misunderstand it,” Mia says of SCTT. The initiative’s aim of raising awareness about science is “absolutely amazing,” Misha adds. “I think it's the best way to kind of make science digestible for the public. In a world where misinformation in science is getting more radical, more dangerous, becoming more of a threat to the trust in scientific infrastructure and foundations, we need such programmes.”Misha and Mia also believe that SCTT can help break down gender stereotypes in science by encouraging young women to study and pursue careers in scientific fields. Both students have benefited from female mentors and encouragement they had when they were much younger. Mia’s love of science began with a class trip to a lab, while Misha — with a smile on her face — says she wanted to study history until “a teacher kind of coerced me into joining a school science club.”Recognition beyond EuropeIn May, Misha and Mia were among the finalists at the Regeneron International Science and Engineering Fair held in Phoenix, Arizona, and involving nearly 1,700 pre-university students from over 60 countries. “It was very crazy because there were so many people and so many teenagers interested in science,” Mia recalls. The event was also challenging. “It was eight hours of continuously presenting your project,” adds Misha.Attending the fair was a chance for the young women to see first-hand the value of international collaboration as well as how research cultures differ. “America is a bit more willing to take risks, and I think that's something we can learn about here in Europe,” Misha explains. However, she continues, “I think Europe has the talent, has the innovation and has the resources” to be competitive.Misha and Mia plan to continue their phage experiments in the new school year, inspired by the project’s hands-on nature and the support they receive from their supervisors. They have also attracted the interest of professional scientists and received invitations to leading research facilities, including the Centre for Synthetic Microbiology, jointly run by the University of Marburg and the Max Planck Institute for Terrestrial Microbiology in Germany. “It is so cool that we can do something to try to move the world in our school and at this age,” Mia says.After completing secondary school, Mia plans to study microbiology and pursue a career in medical research, focusing on Ebola and other infectious diseases. “This has been my dream for so long,” she says. Her friend Misha is interested in biological research with a focus on medicine. “I've gotten addicted to the process of going to the lab, planning out experiments, then failing, trying again,” Misha says. “I think there's just so much to be discovered, so much to be done.”The students' names and photos were published with the permission of their parents.Science|Business, which connects policymakers, academics and industry through its news reporting, analysis and events, is an SCTT partner.
Probiotics are wildly popular. But there’s a better way to help your gut.
Fiber-rich plants — not supplements — are the best fuel for your gut microbiome.
Bausch Health (BHC) Expands Probiotic Skincare Bet To Six New Markets
On September 8, Bausch Health Companies Inc. (NYSE:BHC) and Belgian skincare innovator YUN announced they are extending their microbiome-focused dermatology partnership into Mexico and five additional markets spanning Central and Eastern Europe and Central Asia. The move builds on a 2025 launch in Poland and lands just weeks after the company raised its full-year guidance […]
Is having a ‘gut feeling’ real? What science says about your microbiome
Ever wonder if a "gut feeling" is actually real? Science says yes. Your gut is home to trillions of microbes that play a huge role in both your physical and mental health.
Evvy raises $40M as it seeks to further women's health research with vaginal microbiome data
Women’s health company Evvy announced Tuesday a $40 million Series B led by Catalio Capital Management.
Evvy raises $40M to expand precision medicine for vaginal health
Evvy, a precision medicine company focused on the vaginal microbiome, has raised an oversubscribed $40 million series B round. | Evvy makes an at-home vaginal health test whose results are clinician-reviewed and offers personalized treatment plans, also driving real-world data collection and research on women's health.
Fart-tracking ‘smart underwear’ provides insights on gut health
Smart underwear tracks how often a person farts, offering a non-invasive way to gain insight into how a person’s gut microbiome is functioning.
Traditional Inuit Diet: Foods, Nutrition, and Health Effects
Traditional Inuit diets combine nutrient-dense marine and terrestrial country foods that remain important sources of protein, vitamin D, vitamin B12, iron, and other essential nutrients. The transition toward market foods is occurring alongside changes in cardiometabolic health, micronutrient intake, and gut microbiome patterns, while food insecurity, socioeconomic conditions, physical activity, colonial processes, and environmental change complicate the relationship between diet and health.
Microbiome transplants may curb food allergies
Gut microbe transplants treated some peanut allergies in an early-stage clinical trial.
Small bowel microbiome offers clues to women's health
A new study by investigators at Cedars-Sinai Health Sciences University has identified differences in the makeup and organization of the small bowel microbiome between women and men. The findings, published ...
8 Subtle Signs Your Gut Health Might Be Affecting Your Mood, Skin, or Energy
Gut health is linked to so many facets of overall health that you might not even realize which mental and physical signs actually link back to the state of your microbiome. Here are some common and surprising signs of poor gut health, and easy steps to improve your gut health naturally.
Here's what to eat to protect your mouth's good bacteria
Your oral microbiome is the key to a healthy mouth and body. Here's how to make sure it's well-nourished.
Popular sweeteners may leave effects that last for generations
Two widely used zero-calorie sweeteners, sucralose and stevia, may have effects that linger far longer than the sweet taste itself. In mice, researchers found that both sweeteners altered the gut microbiome, reduced beneficial compounds produced by gut bacteria, and changed the activity of genes involved in metabolism and inflammation. Some of those changes were also detected in later generations that had never consumed the sweeteners themselves.
Norah O'Donnell: Secrets of the gut microbiome and how it impacts our long-term brain health
Common medications may change your gut for years
Common medications may reshape the gut microbiome long after the last dose is taken. In a study of more than 2,500 people, researchers found lasting microbial changes linked not only to antibiotics, but also to antidepressants, beta-blockers, acid-reducing drugs, and benzodiazepines. Some effects were still detectable years later, suggesting past medication use may strongly influence the gut bacteria people carry today.
How a gut health scientist and dietitian eats 50 grams of fiber a day
Fiber feeds the beneficial microbes that live in the gut microbiome and influence our overall health.
Scientists turn probiotic bacteria into tiny drug factories for pancreatic cancer
Engineered probiotic bacteria were able to infiltrate pancreatic tumors, stimulate cancer-fighting immune cells, and slow tumor growth in animal studies. Even more strikingly, the treatment worked better when combined with chemotherapy, radiation, or immunotherapy.
Science Writer Nicola Twilley Discusses Mummy Sleuths, the Hunt for the Ancient Microbiome, and Finding Humanity in the Past
In a recent interview, Nicola Twilley talks about her reporting that followed scientists from the Institute for Mummy Studies as they excavate and glean discoveries from paleofeces preserved in the world’s oldest salt mine, and how that story changed her perspective on humanity and the past. Twilley was a 2025 award winner of the National Academies’ Eric and Wendy Schmidt Awards for Excellence in Science Communications.
Swallowing faecal capsules reduces peanut allergy in six adults
Altering the gut microbiomes of people with peanut allergy using faeces donated from an allergy-free individual improved their peanut tolerance in a clinical trial
What to Eat and What to Avoid for Optimal Gut Health
Gut health can impact everything from sleep to the immune system, so Dr. Roshini Raj, associate professor of medicine at NYU Langone Health, shares her recommendations for preserving your gut microbiome. She shares the signs of an unhealthy gut, and what to eat to improve it. Dr. Raj also shares her tips for avoiding cyclosporiasis.
What Bifidobacteria tell us about gut health and how diet can help
In this interview, microbiome researcher Sudarshan Shetty explains what shapes Bifidobacteria, how they change with age, and what diet can do
Decoding the gut microbiome's symphony in health and disease
The trillions of microorganisms living in our intestine influence our health, from digestion and metabolism to immunity. Yet scientists still struggle to understand how these microbes shape these important physiological functions because gut microbiomes are extraordinarily complex, redundant, and dynamic. New technologies are therefore essential for advancing microbiome research. Researchers at the University of Vienna have now reported effective strategies for simultaneously measuring thousands
Turning fermented food into precision-nutrition for oral and gut health
A new review by researchers at Penn Dental Medicine examines how fermented plant-based foods interact with the microbes that live in the mouth and gut, providing a roadmap for developing fermented foods into nutrition strategies to support health.
Great Barrier Reef microbiome mapped as researchers discover 500 bacterial species previously unknown to science
Research identifies 808,585 viral genomes belonging to what scientists estimate to be 362,802 different viruses
Scientists tested 39 sweeteners and found unexpected gut effects
A large laboratory study found that many commonly used sweeteners can directly change the growth of gut bacteria. Researchers identified more than 100 cases in which sweeteners behaved differently when combined with medications, caffeine, or flavorings. The combination of isosteviol and the antidepressant duloxetine was especially disruptive, reducing beneficial bacteria and overall microbial diversity.
More people are focusing on gut health as fermented foods gain popularity
More people are focusing on their gut health as colorectal cancer rises among young adults and personalized gut microbiome treatments become increasingly popular.
More people are focusing on gut health as fermented foods gain popularity
More people are focusing on their gut health as colorectal cancer rises among young adults and personalized gut microbiome treatments become increasingly popular.
People have been fermenting food for millennia. Here's why more people are focused on gut health now
More people are focusing on their gut health, as fibermaxxing goes mainstream, colorectal cancer rises among young adults and personalized gut microbiome treatments become increasingly popular.
The Unknown Universe Inside Your Gut
The human microbiome is essential to our health, but scientists have only begun to understand why. Two researchers set out to map this largely uncharted terrain.
Microbiome science merges with oncology for better cancer treatments
Cancer remains notoriously difficult to treat, partly because tumors co‑opt their surrounding environment, including the resident microbiota, to evade immune surveillance and resist conventional therapies.
Study Reveals Biology Underlying Oral Health Issues in Down Syndrome
Low saliva from calcium signaling dysfunction, microbiome changes may contribute to high rates of gum disease
Colorado microbiome expert shares ways to improve gut health
UT Health San Antonio identifies the first potential probiotic treatment for lupus
Contact: Steven Lee, (210) 450-3823, lees22@uthscsa.edu Content provided by Claire Kowalick SAN ANTONIO, June 25, 2026 – Scientists at UT Health San Antonio, the academic health center of The University of Texas at San Antonio, found a link between a bacterium in the gut microbiome, or ecosystem, and lupus, which could lead to more effective […]
From soil to gut: why your gut health depends on the world around you
On this World Microbiome Day, we explore the One Health perspective: the idea that human, animal, and environmental health are not separate concerns but expressions of the same interconnected system.
Fermented food microbiome: influence on oral and gut microbiota, and human health
Nature Reviews Microbiology - The bioactive compounds and microbial consortia contained in plant-based fermented foods support oral and gut microbiota, host immune function and metabolic...
8 things to know about the gut microbiome and keeping yours healthy
Wellness influencers often talk about fixing a broken gut microbiome. And marketers sell tests and supplements to fix your gut health. Here's what what the evidence really shows about gut health.
Faecal transplant makes the brains of old mice act young again
Older mice that received a faecal microbiome transplant from younger animals went on to have improved brain plasticity, which meant their brains could overcome a neurological condition that is typically successfully treated only in childhood
K-Beauty's New Frontier: Microbiome Science Hits U.S. Retail Shelves
South Korean brand Lactomedi’s nationwide CVS launch signals a major shift in feminine care, blending K-Beauty innovation with advanced microbiome science.
5 ways to boost your gut health by eating more fermented foods
Scientists have found that eating fermented foods may lower inflammation, improve blood sugar control and increase the diversity of your gut microbiome.
Scientists found a surprising problem with sugar-free diets
A surprising new study suggests that completely eliminating sugar may backfire. Mice on a sucrose-free low-fat diet showed worse blood sugar control, increased inflammation, disrupted gut bacteria, and signs of fatty liver compared with mice that consumed some sucrose. Researchers say the results highlight the importance of a balanced diet and a healthy gut microbiome rather than focusing solely on cutting out sugar.
If stress is wreaking havoc on your gut, late-night snacking may make it worse
Eating late at night may compound the harmful impacts of stress on your digestive health and gut microbiome, according to recent research.
What science has learned about living longer in the last 10 years
From the gut microbiome to the mechanics of cellular aging, here is what a decade of longevity research has revealed about how and why we age
Colorectal cancer risk linked to gut microbiome alterations | Harvard T.H. Chan School of Public Health
More than a decade after removal of an adenoma—a precancerous mass—from the colon, alterations to the gut microbiome and metabolites remain and may drive heightened risk of colorectal cancer, according to a new Harvard Chan School study.
Eating less meat can improve gut microbiome
I read about a study that says it's possible for someone who eats meat to have a gut that's as healthy as someone who is vegan. I know your gut microbiome is an important part of good health, but I'm just not cut out to be a vegan. I'd like to know more about that research.
Yoga and meditation show promise for gut health
This systematic review found that yoga and Buddhist meditation were associated with favorable gut microbiota and metabolite profiles in four human studies involving healthy adults. However, because participants largely followed vegetarian or vegan diets and no randomized controlled trials were included, the findings cannot prove that meditation alone reshapes the gut microbiome.
resbiotic® Launches Gut Health Test In Partnership with Tiny Health: An Advanced At-Home Microbiome Test That Maps What's Really Driving Your Health
resbiotic® (res), a leading physician-developed microbiome health company, today announced the launch of the at-home resbiotic Gut Health Test in partnership with Tiny Health, a precision microbiome platform that delivers a comprehensive picture of gut health — and a clear, personalized plan for improving it.
Secretary Kennedy Brings ‘Take Back Your Health’ Tour to California, Highlights Microbiome Research and Addiction Recovery
HHS Secretary Kennedy traveled to California for his “Take Back Your Health” tour where he visited the City of Hope cancer center and met with local officials.
Scientists discover tiny gut particles that may drive aging and chronic disease
A new study suggests microscopic particles from the gut may actively drive inflammation and chronic diseases associated with aging. Remarkably, gut particles from young animals appeared to counter some aging-related damage in older animals, hinting at new possibilities for future treatments.
How City of Hope is turning microbiome science into better cancer care
For years, clues pointed to the gut microbiome as a key factor in cancer treatment outcomes. Recent advances in gene sequencing are now clarifying its influence on how patients respond to therapy. At City of Hope, this clarity has catalyzed a more comprehensive model for microbiome science in cancer care. We define the microbiome as […]
Your Baby’s Gut Health: What Matters Most in the First Weeks of Life
A baby’s gut microbiome starts developing from the moment they’re born, and those early days can have a lasting impact on immune health and development.
How the bacteria in your gut could raise colon cancer risk
Emerging research suggests the state of the gut microbiome in early life is linked to colorectal cancer—and that both too much and too little bacteria can play a role.
Network topology of the gut microbiome associates with metabolic health in obesity
Nature Communications - Here, the authors show that microbiome network topology associates with metabolic health across obesity phenotypes, with reduced connectivity in metabolically unhealthy...
Scientists reversed liver aging with young gut bacteria in stunning study
Rebooting the gut microbiome with bacteria from youth may help stop aging-related liver damage and even prevent liver cancer, according to new research in mice. Older mice that received their own preserved youthful microbiome showed less inflammation, reduced DNA damage, and no signs of liver cancer. Researchers also found that the treatment suppressed a cancer-linked gene called MDM2, making older mice biologically resemble younger ones.
Want a Better Brain? New Science Says Coffee Has a Big Benefit You Didn't Know About
New research suggests that both regular and decaf coffee may support gut health, mood, and cognition through changes in the gut microbiome.
Bryan Johnson tweet draws attention to vaginal microbiome. What is that?
Bryan Johnson tweeted his wife's vaginal microbiome test results. We spoke to OBGYNs and longevity advocates about what that is and if you should do it too.
Science Has Found Even More Ways Coffee Is Good for You
A new study shows the mechanisms of how coffee modifies the microbiome, reduces inflammation, and influences mood. Even decaf has its perks.
Your oral microbiome could affect your weight, liver and diabetes risk
An ambitious study has explored how the oral microbiome may affect our metabolic health, raising hopes that conditions like pre-diabetes could one day be screened for via a simple mouth swab
One Health Microbiome Center names next doctoral interns for industry program
Two Penn State doctoral students will spend eight weeks in Germany at the headquarters of global biotechnology company QIAGEN. This marks the third year of the program, a partnership between the One Health Microbiome Center and QIAGEN.
Your daily coffee habit may be quietly reshaping your gut and mood, study finds
A new study from APC Microbiome Ireland finds that habitual coffee consumption alters gut bacteria, influencing mood, stress and cognitive sharpness.
Centipede consumption boosts growth and gut health in endangered crocodile lizards
A new study in Biological Diversity reveals that centipede consumption enhances growth and gut microbiome homeostasis in juvenile crocodile lizards by enriching beneficial fermentative bacteria and elevating short chain fatty acid production, underlining the critical role of dietary diversity in the conservation of endangered reptiles.
WATCH: Science graduate students recap international industry internship
Penn State graduate students Samantha Seibel and Naomi Huntley discuss their participation in a six-week summer internship program in Germany that was made possible by a partnership between QIAGEN LLC and the University's One Health Microbiome Center.
‘Smart Underwear’ Measures Gut Gas for Microbiome Science
Device snapped into underwear monitors flatus frequency in real time to set a new baseline for what’s typical and gain insight into microbiome activity.
The Intersection Between Gut and Spine Health
Emerging research is showing more and more connection between the two.
A global consensus establishes a basis for measuring and improving gut health
While “gut health” is becoming a popular term, mainly in media and marketing claims but also in the clinical context, researchers have not yet nailed down a definition. Now, a global group of 13 scientists and clinicians updates a consensus definition of gut health and implications from bench to bedside.
Scientists discover hidden gut signals that could detect cancer early
A new study reveals that gut bacteria and metabolites may hold the key to detecting serious digestive diseases earlier and more easily. Using AI, scientists found that biomarkers linked to one condition can often predict others, showing these diseases are more interconnected than previously thought. This cross-disease insight could lead to faster diagnoses without invasive procedures.
New Webinar Series Explores Relationship Between Microbiome and Health
The free virtual series is open to students, researchers, clinicians and anyone from the public with an interest in microbiome science.
Sharing her passion for science
By Danielle Rush Communications Specialist, Indiana University Kokomo Hisako Masuda, Indiana University Kokomo professor of biochemistry, was honored by the Indiana Academy of Science (IAS) as its 2026 Distinguished Scholar. The award is given to an individual who is recognized by the IAS as having an exceptional record of scholarship. Recipients are selected from nominations submitted to its awards committee. “I was surprised,” said Masuda, who joined IU Kokomo’s faculty in 2013. “I feel there are many good scientists in the Academy, so I wasn’t expecting it at all.” Patrick Motl, dean of the School of Sciences, said the Academy recognizes up to one member per year, and that Masuda is the second or third IU Kokomo faculty member to receive the commendation. “Clearly this speaks to the strength of Dr. Masuda’s accomplishments in research and scholarship and that her work stands out amongst her peers in Indiana,” said Motl, who received the award in 2019. “Many of the institutions that participate in the IAS are undergraduate institutions or primarily undergraduate institutions, but even having that caveat, Dr. Masuda has built and maintains a very active research program in her lab, working exclusively with undergraduates. She is passionate about science and can share that passion with her students. To carry on a quality research program with so many students involved in so many projects is truly remarkable and I am glad that the IAS acknowledged that for Dr. Masuda.” The IAS specifically commended her for involving more than 50 undergraduates in her research in bacterial metabolism, genomics, and their phenotypic plasticity at IU Kokomo, and publishing 23 articles with many student co-authors. Masuda’s current work primarily focuses on biodegradation and chemical repurposing of nylon. Using soil bacteria, her lab studies bacterial biodegradation of nylon and other environmental pollutants. She applies principles of green chemistry while developing a method to convert nylon waste into other nontoxic polymers. In collaborative work with health scientists, her lab investigates gut microbiomes of Indiana native birds as well as human subjects in a clinical study. She became interested in converting plastic waste while earning her Ph.D. at Rutgers University, working on methods to remove environmental waste not using chemicals or other intrusive methods. She learned about Nylon 11, which is used in pipes for transferring oil, interior components for cars, catheters, and in other industrial hard plastics. Nylon 11 is nontoxic, she added, so it is safe to include students in the research. “Those are considered to be nonbiodegradable, and have to go to a landfill,” she said. “I thought if we could come up with a way to biodegrade it, that would make some kind of impact.” Eventually, she wants to develop a product that would convert nylon waste to something useful, and to reduce waste and microplastics in the environment. “That would be my goal at some point, that we can make that change, and also make people more aware of their use of plastics,” she said. “I hope students stop to think about what we can do as scientists to address issues currently impacting us.” She appreciates the IAS for its support of scientific research at Indiana institutions, and IU Kokomo and the School of Sciences for providing funding for students to attend the Academy’s annual meeting. She added that IU Kokomo has also supported her research with funding from the School of Sciences and Academic Affairs. “Without that, I couldn’t do my research,” she said. Masuda has also earned a Senior Research Grant from the IAS, IU Kokomo’s Distinguished Research Award, and the IU Kokomo Junior Faculty Annual Research Award. She is a Fellow of the Indiana Academy of Science. Education is KEY at Indiana University Kokomo.
Ingredion and Holobiome map gut microbiome to unlock targeted health benefits
Ingredion has partnered with Holobiome to use AI and its database of two million bacterial genomes to predict how specific ingredients will interact with human health before clinical trials. The research expands beyond digestion to explore how sweeteners, plant proteins, and texture solutions influence the gut-brain axis, including sleep and mental health.
Scientists Stunned: Colossal Eggs Discovered 3,500 Meters Beneath an Active Volcano
Beneath an active seafloor volcano off Vancouver Island, researchers have documented a congregation of giant eggs at roughly 3,500 meters, a discovery that reframes how life can flourish under extreme conditions. The eggs belong to the Pacific white skate, an elusive deep‑sea species adapted to cold, crushing pressure and perpetual darkness. What seemed an unlikely nursery is actually a geothermally warmed refuge, where subtle heat helps embryos survive a marathon incubation. The finding links volcanic energy to a quiet engine of biodiversity, turning a hostile landscape into an incubator. A living volcano, a hidden nursery The seamount long assumed dormant now exhales mineral‑rich, shimmering plumes, proof of hydrothermal life at depth. Expedition cameras swept across black basalt and pale bacterial mats, revealing vents that pulse with warmth. That warmth, though modest by human standards, alters the physics of development for cold‑adapted embryos. In a realm where metabolism creeps, even a few degrees can mean faster growth and higher survival. The volcano is not only active; it is ecologically formative, drafting a blueprint for a thriving oasis. Giant eggs and a skate built for the abyss The Pacific white skate, Bathyraja spinosissima, is built for the abyss: broad wings, armored spines, and a life history that trades speed for endurance. Females lay outsized, rectangular “mermaid’s purses,” often 46–50 centimeters long, packed with rich yolk to fuel years of growth. In the frigid deep, embryos can require around four years to hatch, a timeline that magnifies every energetic advantage. The scale is striking—large eggs, large adults, and a textbook case of deep‑sea gigantism. The volcano’s gentle heat may literally shave months or years from the wait. Why heat matters at the bottom of the sea Hydrothermal circulation delivers low‑level warmth without the turbulence that would scatter fragile egg‑cases. Slightly elevated temperatures accelerate enzyme kinetics, nudging development along while keeping embryos within a safe range. Mineral‑laden fluids likely shape local microbiomes, which, in turn, can influence biofilms on egg surfaces. The environment acts like a slow, steady incubator, countering the deep sea’s tyrannies of cold and scarcity. For a species with long maturation and few offspring, every incremental boost compounds across generations. An ecosystem sculpted by fire and water Seafloor volcanoes create steep environmental gradients, stitching together hot vents, cool eddies, and mineral gardens into mosaic habitats. Microbes harvest chemical energy, seeding food webs that support crustaceans, fishes, and skates. Cameras documented egg‑cases nestled among rocky ledges, near communities nourished by vent‑driven chemistry. These islands of productivity behave like deep‑sea oases, sustaining life far beyond the vent orifice’s flickering light. The nursery’s success underscores how geological forces engineer biological opportunity. “Finding a cradle of life tucked beneath a breathing volcano reminds us that the planet’s harshest places can be profoundly generous.” What the discovery could change The nursery reframes conservation priorities in regions where volcanism quietly underwrites reproduction. Protecting hydrothermal corridors could safeguard entire lifecycles, not just charismatic adults spotted during occasional surveys. It also sharpens questions about how climate‑driven shifts in ocean circulation might influence vent activity, temperature fields, and embryo survival. With methodical mapping, time‑series cameras, and environmental DNA, scientists can track whether nurseries remain stable or drift with geologic rhythms. Key implications include: Enhanced understanding of deep‑sea reproduction at hydrothermal sites. New conservation targets centered on geothermal nurseries. Comparative studies with other volcanic regions, from the Galápagos to rift zones. Biotechnological insights from organisms adapted to long, cold development. Better models of how seafloor heat shapes regional biodiversity. Methods behind the revelation Remotely operated vehicles threaded through chimney fields, gathering video, temperatures, and mineral signatures. High‑definition imagery captured the distinctive, horned egg cases, their edges dusted with fine volcanic silt. Geochemical profiles mapped how heat and chemicals disperse, outlining the “thermal lanes” where eggs most cluster. Combined, these datasets reveal a nursery organized by geothermal topography, with egg‑cases concentrated in pockets of gentle, sustained warmth. A fragile boon in a changing ocean Deep‑sea environments feel remote, yet they intersect with global pressures: mining proposals, cable routes, and shifting oxygen levels. The nursery’s resilience hinges on stable heat flow, intact substrates, and minimal disturbance from noise or sediment. Safeguarding such places is not just about protecting novelty; it preserves a slow, ancient strategy that lets large, long‑lived animals endure in the coldest reaches of the Pacific. Where geology and biology meet, the planet’s deep time still writes living stories. This volcano‑warmed nursery adds a vital chapter to that story, revealing how subtle thermal gifts can tip the scales toward life in the abyss. With each dive, researchers trace the contours of an unseen world, where fire feeds water, and water—against all odds—feeds the future.
Scientists find gut bacteria inject proteins that control your immune system
Gut bacteria aren’t just passive passengers—they can actively send proteins straight into our cells. Using microscopic injection systems, even harmless microbes can influence immune responses and metabolic pathways. Researchers found these interactions may play a role in inflammatory diseases like Crohn’s. It’s a major shift in how scientists understand the microbiome’s power over human health.
Glyphosate: A story of science, risk, and nuance
In the summer of 2014, a California groundskeeper named Dewayne Johnson started noticing patches of raw, weeping skin spreading across his body. He had spent years applying Roundup, Monsanto’s glyphosate-based herbicide, for a school district, sometimes drenched in it when equipment malfunctioned. By 2014, he had a diagnosis: non-Hodgkin’s lymphoma. In 2018, a jury awarded him $289 million in damages, later reduced on appeal. Tens of thousands of lawsuits followed. The story hasn’t quieted down. It’s all over the internet, swinging between “this will kill you, buy organic” and “relax, you’re fear-mongering.” Some of that recent chatter stems from an Executive Order protecting glyphosate and its production, which set off intense infighting within the MAHA movement. Some of it reflects a deeper truth: Americans genuinely care about harmful chemicals in their environment (see poll below). And the conversation isn’t going anywhere, with a Supreme Court case involving Monsanto set for this April. Glyphosate (the active ingredient in Roundup) is one of the most widely used herbicides in the world. But does glyphosate cause cancer? And how much exposure is actually risky? With so much mistrust in institutions and corporations (and some genuine conflicts of interest), making sense of the actual scientific evidence is genuinely hard. Here is a translation of what the scientific evidence actually says. Does glyphosate cause harm? Glyphosate is an herbicide that kills most plants it contacts rather than targeting specific species. It works by blocking an enzyme pathway (EPSPS) that plants and many microorganisms need to produce essential amino acids. Without those amino acids, the plant can’t grow and dies. Glyphosate was first developed by Monsanto in the 1970s and became ubiquitous after the company introduced “Roundup Ready” crops in the 1990s. In 2024, Bayer removed glyphosate from residential Roundup-branded products due to litigation pressure. But today it is still the most widely used herbicide in the world. Farmers also discovered they could spray it directly on crops like oats, lentils, beans, and peas just before harvest to dry them out faster and make harvesting easier. Because of its widespread use, it’s obviously really important to understand if it’s harmful to humans. The key principle: The dose makes the poison The most important concept in toxicology is that “the dose makes the poison.” Sixteenth-century physician Paracelsus articulated what remains the foundational principle of toxicology: sola dosis facit venenum. Water will kill you if you drink enough of it. Aspirin saves lives at 81 milligrams and causes internal bleeding at higher chronic doses. So, at what dose is glyphosate poisonous? The LD50 in rats (the dose that kills half the test animals) is around 5,600 mg/kg body weight. Table salt is roughly 3,000 mg/kg. By that classic measure, glyphosate is less acutely toxic than salt. But some people are exposed to a lot of glyphosate through their work. And among the general public, there are many questions about low-dose, cumulative exposure from multiple sources over long periods. Does glyphosate cause health problems? Cancer Correlation maps are striking, with one analysis finding that 60% of counties that spray the most glyphosate have non-Hodgkin’s lymphoma rates above the national average. But correlation alone doesn’t establish cause, which is why animal and human studies matter. In animals: Rat studies are typically what most fear is rooted in, but most people don’t know the study details on the dosage given to rats. A pooled analysis of the 13 most rigorous rat studies found evidence that very high doses, around 55,000 times greater than typical food residue exposure, can cause certain cancers. In humans: One of the strongest studies followed 55,000 herbicide users over 20 years and found no overall increased cancer risk. There was one signal: among those with the highest use, rates of acute myeloid leukemia (AML) appeared elevated. A broader meta-analysis of 18 human studies also found no overall cancer risk, though a separate meta-analysis focused specifically on non-Hodgkin lymphoma found that people with high cumulative glyphosate exposure faced a 41% higher relative risk compared to those with low or no exposure. These human studies are observational studies (randomized controlled trials would be unethical), and meta-analyses are only as reliable as the studies they pool. But the story seems consistent: at very high exposure levels, there may be some cancer risk. But that’s about as far as the science currently takes us. Emerging research: gut and reproductive health Gut: Because glyphosate targets a pathway that exists in some gut bacteria, scientists have questioned whether it could affect the microbiome. In mice, a 2023 University of Iowa study found that glyphosate altered gut bacterial composition and raised markers of intestinal inflammation. A 2024 systematic review found similar patterns: disrupted gut bacteria and problems with the mucus layer that protects the intestinal wall in mice. Whether this translates to humans is an open question. The human gut is highly variable and resistant, and we don't yet have strong studies confirming the same effects in people. Reproductive health: Animal studies have found that glyphosate-based herbicides can interfere with reproductive hormones, including disrupting egg cell development in mice and reducing the number of eggs available in sheep’s ovaries. However, the doses used in these experiments were high, so it’s not yet clear whether the same effects would occur in humans. On the human side, a 2021 pilot study led by Mount Sinai researchers tested urine samples from pregnant women across the U.S. and found glyphosate in 95% of them. The study also found a possible connection between higher glyphosate exposure during pregnancy and a subtle physical difference measured in female newborns. That said, some connections weren’t statistically reliable and this was a small study. The researchers themselves said more and larger studies are needed before drawing firm conclusions. What do regulators say about glyphosate safety? In 2015, the International Agency for Research on Cancer (IARC), part of the World Health Organization, classified glyphosate as "probably carcinogenic to humans" (Group 2A). The classification is worth taking seriously. But, there’s an important distinction: IARC classifies hazard, meaning the potential to cause harm under some conditions. It does not assess risk, which accounts for actual exposure levels and the real-world probability of harm. The U.S. EPA, the European Food Safety Authority, Health Canada, and regulatory agencies in Australia and Japan have all concluded that glyphosate is “unlikely to be carcinogenic to humans” at realistic exposure levels. They’re asking a different question: given how much of this people actually encounter, what is the probability of harm? Your actual exposure is what determines your actual risk. What does glyphosate mean for your daily life? At the grocery store: Food residues are small. The EPA’s acceptable daily intake is 1.75 mg/kg of body weight per day. To hit that threshold from oatmeal alone, a 150-pound adult would need to eat roughly 50 pounds of oats every day. But this calculation addresses only one pathway (food), and we don’t yet have robust tools to measure people’s actual total exposure. If reducing exposure matters to you, organic certification prohibits synthetic herbicides, and organic oat products generally test at lower or undetectable levels. Either way, a diet rich in whole grains, conventional or organic, is far better for your health than one that omits them out of fear of residues. On the farm: Occupational exposure is orders of magnitude higher than consumer exposure. Farmers and farm workers who mix, load, and apply glyphosate-based herbicides, especially without protective equipment, face meaningfully different risk profiles. Proper PPE isn’t optional. Integrated weed management strategies that rotate chemical modes of action are also worth taking seriously, both for health and for long-term effectiveness. If you live near a farm: Spray drift is real. Concentrations near field edges can spike during and after application, particularly on windy days. This is an area where I think public health could really step up and empower rural communities with buffer zones, rather than placing the onus on individuals. But for now, knowing your local agricultural calendar and keeping windows closed during application are the first steps. Bottom line Dewayne Johnson was exposed to glyphosate at levels most people will never encounter, and a jury decided he deserved compensation. That outcome is not evidence that the oatmeal in your pantry is dangerous. But it is a reminder that the dose, the context, and the person doing the exposing all matter enormously. Glyphosate is a chemical tool with benefits, trade-offs, and genuine open scientific questions. Learning to hold that complexity without collapsing into panic or dismissal is, honestly, one of the most useful and hardest things to do in navigating modern health science. Love, YLE Your Local Epidemiologist (YLE) is founded and operated by Dr. Katelyn Jetelina, MPH PhD—an epidemiologist, wife, and mom of two little girls. Hannah Totte, MPH, is an epidemiologist and YLE Community Manager. YLE reaches more than 425,000 people in over 132 countries with one goal: “Translate” the ever-evolving public health science so that people will be well-equipped to make evidence-based decisions. This newsletter is free to everyone, thanks to the generous support of fellow YLE community members. To support the effort, subscribe or upgrade below: Subscribe
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