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Women's Fund to honor four with Dream, Achieve, Inspire awards
NEW HARTFORD — The Women’s Fund of Herkimer and Oneida Counties is celebrating its work supporting women and girls with a dinner at the Yahnundasis Golf Club, 8639 Seneca Turnpike,
Brian Schottenheimer Must Answer for More Than the Offense
Brian Schottenheimer faces scrutiny after the Cowboys’ loss to Tampa Bay exposed problems that extend beyond the offense and into his entire team.
The Broad to move works to Paris and Leimert Park during construction
The Broad will display more than 160 works in a major exhibition at the Fondation Louis Vuitton in Paris during its final phase of construction. It will also partner with Art + Practice in Leimert Park.
Scientists restore memory-linked neuron function in Alzheimer's mice
Researchers were able to restore the function of neurons linked to cognitive function and information processing in mice that mimic key features of Alzheimer's disease, showing early promise for the development of a similar targeted therapy in humans.
Eagles sign quarterback Joe Milton off Cowboys' practice squad
The Philadelphia Eagles signed quarterback Joe Milton off the Dallas Cowboys' practice squad, Cowboys coach Brian Schottenheimer confirmed Friday.
The Trump Admin Is Airing Yet Another Taxpayer-Funded Political Ad
The video, originally from Trump's 2024 campaign, shows the president vowing to destroy "villains" with the disclaimer, "Paid for by the U.S. Government."
Netflix Needs To Put The Same Disclaimer On Both Monster And Unabomber
My head is spinning after both.
Packers-Falcons Game Primer: How to watch tonight’s TNF game
Here are all of your critical game details for tonight’s contest.
Can we harness the brain's deep-cleaning system to prevent Alzheimer's?
The glymphatic system is the brain's recently discovered network for flushing out toxins. Now, we're uncovering surprising ways to boost it to protect brain health
HOMETOWN ENTERTAINMENT: Comedy about the French Revolution opens this week at Showtimers Community Theatre
French Revolution-themed comedy opens at Roanoke theatre.
Hershey changes Reese’s Pumpkins packaging after lawsuit over design
A new disclaimer is appearing on Reese’s Peanut Butter Pumpkins after litigation over claims that the decorative designs shown on the packaging did not match the actual candy.
WATCH: NH's 1st Congressional District forum with DiLorenzo and Shaheen
Tune into a livestream of our candidate forum with Republican Anthony DiLorenzo and Democrat Stefany Shaheen, starting at 6 p.m. on Oct. 6.
Study: Does earlier menopause onset mean faster cognitive decline?
A new study found that women who experience earlier onset menopause had earlier cognitive decline and were diagnosed with Alzheimer's sooner.
Brian Schottenheimer's message to Cowboys in Rio: 'It's a business trip'
Rio is one of the most beautiful places in the world, but as the Dallas Cowboys prepare to take on the Baltimore Ravens in Brazil, the message from Brian Schottenheimer is crystal-clear.
Houston Rockets Position Primer: Point Guard
Taking a look at the point guard position for the Houston Rockets.
Who gets Alzheimer's drugs? Race, vulnerability and health status shape access
The first disease-modifying drugs for Alzheimer's disease offer patients the ability to slow cognitive decline by targeting amyloid plaques in the brain. But a new study suggests that not all patients ...
Early-onset Alzheimer's disease shows different warning signs from established risk factors
A study by the University of Oulu and the University of Eastern Finland found that people who developed Alzheimer's disease before the age of 65 accumulated a wide range of health problems, particularly ...
Breitling Adds Two New Manual-Wind Navitimers To The Core Collection
✓ Breitling has just introduced a pair of new manually-wound Navitimer models to its core collection ✓ Check it out! ✓
Cowboys news: Brian Schottenheimer is feeling the pressure
Here is today’s Dallas Cowboys news.
Will We Ever Understand Dementia?
Since the days of Dr. Alzheimer himself, there has been a dream that severe senility might have an explanation — and a cure. The search for both has never been more urgent.
Schottenheimer reveals shocking new org chart for Cowboys coaches
The Cowboys are not making things any simpler, as they look to change how things are working for their defense.
Alzheimer's Awareness: Aging Brain Clinic at UNC Health serves as one-stop shop for memory-loss answers
"It can be very helpful for people to have somebody say, 'This is what I think is going on with you.'"
Symposium highlights MIT’s wide range of innovations for aging brain health
In six talks, researchers from across MIT described Aging Brain Initiative projects aimed at advancing the understanding of and interventions against neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and ALS.
Letter to the Editor - Defeat Article 10 – It Is Bad Business For Westford
Michael Furman, Westford Resident Defeat Article 10 – It Is Bad Business For Westford Let me start out with a disclaimer. I am a member of the CPC (Community Preservation […]
Study shows link between Alzheimer’s disease and gut health
Researchers found that people with higher levels of imidazole propionate (ImP), a compound produced by certain gut microbes, were more likely to show signs of Alzheimer’s disease.
Glucosamine, a popular joint supplement, linked to faster Alzheimer’s progression
A large health-record analysis found that glucosamine use was associated with a 25% higher likelihood of mild cognitive impairment progressing to dementia. Lab experiments suggest the popular joint supplement may intensify an abnormal sugar-tagging process in the Alzheimer’s brain, although researchers say clinical trials are needed to determine whether it actually causes harm.
Yale School of Medicine On the Science of Childhood Anxiety, Say, Anxiety Disorders Are the Most Common Mental Health Challenges In Youth
Credit: Matt Bradbury October 5, 2026 - By Isabella Backman - Anxiety disorders are the most common mental health challenges in youth. Left untreated, they can disrupt the lives of both children and their families. The good news is that with intervention, most children will overcome these conditions. Across Yale School of Medicine, scientists are working to understand anxiety at every level, from common anxious behaviors to molecular biomarkers in the brain. They are using their findings to develop and disseminate new evidence-based treatments for childhood anxiety. Today, the go-to treatment for childhood anxiety disorders is cognitive behavioral therapy (CBT). This is a form of psychotherapy that teaches children skills for confronting anxious thoughts and helps them practice managing situations that cause anxiety. While it is the gold-standard treatment backed by considerable scientific evidence, up to 50% of children will not see sufficient benefit from CBT alone. Wendy Silverman, PhD, Alfred A. Messer Professor in the Child Study Center, co-directs the Anxiety and Mood Disorders Program alongside Eli Lebowitz, PhD, associate professor in the Child Study Center. One of their main interests is learning how to improve outcomes beyond CBT. “We’re developing cutting-edge, research-based knowledge that can reduce the suffering that anxiety causes children and their families,” says Silverman. Changing parent behavior YSM experts are investigating how to improve CBT outcomes for children by involving the parents. Silverman’s research has uncovered two main components of parent intervention that improve childhood anxiety: not enabling children to completely avoid the things that make them anxious and taking steps to enhance their autonomy. Parents may unintentionally reinforce their child’s anxiety by allowing them to avoid what makes them anxious. They also may unintentionally limit the children’s sense of autonomy by being overly intrusive. “One of the things that we take pride in is that we’ve focused on trying to understand what parents need to do, and to test our ideas and see if changing the parents’ behaviors is enhancing the effects of CBT,” Silverman says. “Our findings thus far suggest that they do." As much as CBT can be helpful, it can also be challenging to get one’s child to do the necessary steps for CBT to work. This is one important reason why Lebowitz created a novel intervention program for parents named Supportive Parenting for Anxious Childhood Emotions (SPACE). Existing intervention programs often teach parents to act as therapists for their child, such as training them on how to practice breathing exercises. “It makes sense, but this doesn’t work very well in practice,” says Lebowitz. “And part of the reason, I think, is that it’s not easy to get your kid to do things, especially if they’re not excited about doing it.” SPACE is unique because it focuses entirely on parent involvement and changing parental behavior—children are not involved in the sessions. For example, parents learn how to use supportive messages that convey confidence that their child can tolerate and manage distress. “It might sound like a parent saying to a child, ‘I get that this is really hard for you, but I know that you can handle it,’” Lebowitz says. The program also works with parents to identify the ways in which they are accommodating anxious behaviors. “We’ll pick one thing that parents are doing that is an accommodation and help them make a detailed plan for how they’re going to change that,” Lebowitz explains. Treating Anxiety in Children and Adolescents Much of the existing research on SPACE has focused on parents of children under age 14. Ongoing studies are now exploring its use with parents of older teens. “Both anxiety and accommodation can interfere with normative developmental shifts during the teen years, including increased autonomy and individuation from parents,” says Rebecca Etkin, PhD, associate research scientist in the Child Study Center. “In this sense, SPACE may be particularly well-suited for anxious teens and their parents. We want to see whether it is effective during this distinct developmental window.” Unfortunately, many families in need of CBT face barriers, including limited availability of services and geographic constraints. One way to improve access is digital interventions. Silverman and her team are developing an evidence-based digitized intervention program for parents that they can access directly from their computer or smart phone. “The work we’re doing will be one of the very few parent interventions that is digitized and importantly tested for effectiveness,” she says. Creating interventions for anxiety-related challenges Silverman and Lebowitz recently received a generous gift to develop and test other interventions that help parents reduce other child anxiety-related behavioral and emotional difficulties, such as restrictive eating and unexplained somatic symptoms. One of these projects in particular focuses on understanding the risks of social media and its potential benefits, including offering a sense of connection. “A lot of research has focused on the idea that social media is harmful and the less of it the better,” says Lebowitz. “But we actually see is that this is not quite right—there are negatives, but there are also positives. So, we’re trying to get a little bit more nuanced of a picture.” The team is working with teens with social anxiety and their parents over an extended period to better understand their social media habits and how their anxiety levels affect engagement with different platforms. The teens will answer questions sent to an app on their phones about mood and social media usage in an effort to capture emotional responses as they unfold. “We hope to develop interventions that can help make the best of social media while protecting against the more problematic effects,” Lebowitz says. The brain’s role in anxiety Researchers are also testing therapies to address anxiety at the neurological and molecular levels. In collaboration with Dylan Gee, PhD, professor of psychology in Yale's Faculty of Arts and Sciences, and Hilary Blumberg, MD, John and Hope Furth Professor of Psychiatric Neuroscience at Yale School of Medicine, Lebowitz and Silverman are using brain imaging to identify changes in a child’s brain before and after parents enroll in SPACE. In one study, children viewed anxiety-inducing images while undergoing magnetic resonance imaging (MRI); the researchers conducted scans with and without the children’s parents nearby. Before SPACE, children’s brains were better able to activate the regulatory circuitry needed to turn off an anxious response when their parents were nearby. But after SPACE, children could activate this circuitry even without the parent around. “As parents work on gradually reducing some of their accommodations, you can see a child get better at regulating their own fear system in the brain,” Lebowitz says. “It’s remarkable.” Research into the molecular underpinnings of anxiety can also inform new childhood anxiety treatments. In a recent study, Lebowitz, Silverman, and Flora Vaccarino, MD, Harris Professor in the Child Study Center, discovered that a protein known as fibroblast growth factor 2 (FGF2) could be protective from the toxic effects of stress. FGF2 levels in children and their parents were linked to the children’s risk of developing anxiety and depression, the study showed. The findings could help explain why some children who are exposed to early life trauma such as poverty or abuse are more prone to developing mental health disorders. And FGF2 could be a target for treatment. “This is very novel because it starts to give a clue to what is the molecular chain that connects those lived experiences to the actual psychological outcomes,” Lebowitz says. New ways to study and treat childhood anxiety Michael Crowley, PhD, associate professor in the Child Study Center, collaborates with Silverman and Lebowitz to study the role that attention plays in development and maintenance of childhood anxiety. There is a large body of research that shows that anxious children, like anxious adults, are prone to focus on threatening stimuli such as angry faces compared with neutral faces. This has led to innovative interventions that involve attention retraining. The idea is that if experts train children to look away from threatening stimuli, it may reduce their anxiety—especially children with social anxiety who are most prone to attend to threats. The researchers have just completed a clinical trial for attention retraining with 10- to 14-year-olds with social anxiety disorders and are currently analyzing the findings. Besides this innovative attention retraining research, as Crowly notes, “I like to design tasks that are engaging to kids,” Crowley says. “My goal is to assess something without the kids knowing what we are assessing.” With this goal in mind, Crowley has created a virtual game, named Boom, to study threat processing in children with anxiety disorders. The game is similar to that of hot potato—the child and three digital players take turns virtually passing a ball to each other’s gloves. At some point, the ball turns into a bomb, and as the bomb lands in each player’s glove, the outline of the glove turns yellow. The goal is to avoid having the bomb go off in your glove. What isn’t obvious is that the game is designed to measure different types of threatening stimuli, both ambiguous and direct. In the game, the direct threat occurs as the bomb is traveling towards your glove. The ambiguous threat is the yellow outlined glove as it is unknown where the bomb will travel next. While children play the game, Crowley’s team measures their brain activity using electroencephalography (EEG). The researchers have discovered that in kids with anxiety, the brain reacts more strongly to ambiguous threats than it does in their peers, but less strongly to direct threats. They believe that the initial abnormally large brain response to not knowing where the bomb is going impairs the brain's ability to properly respond when the threat is actually traveling the child’s way. “The brains of children with anxiety are unable to differentiate between threats you need to do something about and those that are not your problem.” Michael Crowley, PhD, develops innovative games for studying anxiety in children and adolescents.Credit: Matt Bradbury Based on these insights, Crowley hopes to study whether interventions like attention training could restore appropriate threat processing. Crowley’s team is also working on a test called the Balloon Risk Avoidance Task, which evaluates risk-taking and avoidance behaviors. It features a digital balloon that is full of air and about to burst. Kids have six seconds to let air out of the balloon. The more air they let out, the less risk they face that the balloon will pop. But at the same time, the balloon becomes less valuable as it deflates. “The more air you keep in the balloon, the more points you get,” Crowley explains. So far, the researchers have found that when the balloons pop unexpectedly, teens with social anxiety show distinct brain responses. Studying these responses can help psychologists understand the underlying pathways driving the various manifestations of anxiety. The genetics of anxiety When Thomas Fernandez, MD, associate professor in the Child Study Center and of psychiatry, was still in training, there was a lot of excitement about understanding the genetics associated with autism spectrum disorder. Since then, scientists have identified around 250 genes associated with autism. The genetic contribution to anxiety disorders, on the other hand, has historically received less attention. Anxiety is less heritable than autism, but the genetic contribution for anxiety disorders that emerge in childhood may be higher than for anxiety disorders overall. While scientists estimate the heritability of anxiety disorders in general to be around 30% to 50%, some studies suggest higher heritability for certain childhood-onset anxiety presentations. “I saw firsthand how researchers in the field went about finding vulnerability genes for autism,” Fernandez says. “So, we’re using a very similar playbook for childhood anxiety.” “I saw firsthand how researchers in the field went about finding vulnerability genes for autism. So, we’re using a very similar playbook for childhood anxiety.” Thomas Fernandez, MD Associate Professor In the Child Study Center and in Psychiatry Now, Fernandez and Emily Olfson, MD, PhD, assistant professor in the Child Study Center, are studying children and their parents to identify genetic changes that are present in the child but not the parents, known as “de novo mutations.” “All of us have some de novo mutations—maybe about 50 to 100 sprinkled throughout the genome,” Olfson says. “But when they occur within the coding regions of genes, they can be really disruptive.” Previous research shows that people with autism have higher rates of damaging de novo mutations than the general population. In 2022, Olfson, Lebowitz, Silverman, and Fernandez published a study on 68 children and their families that found that children with anxiety had similarly high levels of these mutations. Studying de novo mutations can help point the researchers to where they should be looking for genes associated with anxiety. “The end game is using the genes to steer us toward the right part of biology that we can then target to come up with better treatments,” Fernandez says. Building on those findings, the team is now studying more families to better understand how these de novo mutations, along with other genetic and environmental factors, shape pediatric anxiety disorders. They recently received a National Institutes of Health grant to enroll 750 new families over the next five years. Olfson is the principal investigator, with co-investigators Lebowitz, Fernandez, Silverman, and Shuangge Steven Ma, PhD, department chair and professor of biostatistics at Yale School of Public Health. Neurodevelopment, Risk Genes, and Mental Health Conditions - The Olfson Lab Joel Gelernter, MD, Foundations Fund Professor of Psychiatry, is interested in how different anxiety disorders differ genomically. “We are studying social phobia, panic disorder, and generalized anxiety disorder, working to understand why people differ in their risk to these specific anxiety disorders and evaluating various risk factors,” he says. Gelernter was recently involved in one of the largest studies to date of the genomics underlying anxiety disorder. The study included around 122,000 people with anxiety disorders and around 730,000 without. It found that some genetic differences associated with anxiety were linked to signaling that helps reduce overactivity in the nervous system. Many anxiety medications available today work by targeting this process. “It’s nice when the biology that you get out of a large genome-wide study ratifies things that we already know because that can help increase confidence in further findings from the study,” Gelernter says. Uncovering the neurobiology of psychiatric disorders John Krystal, MD, Robert L. McNeil, Jr. Professor of Translational Research and chair of the Department of Psychiatry, is interested in the neurobiology of psychiatric disorders, including post-traumatic stress disorder (PTSD), of which anxiety is a major symptom. In the late 1980s, Krystal’s team discovered that the drug yohimbine activated symptoms in patients with PTSD. “This was the first time we could link a specific biological mechanism to the symptoms of PTSD,” Krystal says. At the time, he adds, this finding was highly controversial. “A lot of people felt that PTSD was a purely psychological syndrome that didn’t have an underlying biology.” Since then, Krystal has dived deep into understanding the neurobiology of PTSD to learn how to better treat it. His team is evaluating the use of ketamine and psychedelics. These would be among the first treatments to be developed specifically for PTSD. They may also be applicable for other disorders including anxiety disorders, Krystal adds. An important gap in PTSD treatment is the absence of biological tests that inform how to best help patients manage their PTSD symptoms. A doctor doesn’t diagnose cancer based on how they feel. Rather, they use tests of the biology of the cancer to determine the best course of treatment. “And we can’t do that in any psychiatric disorder other than Alzheimer’s disease,” Krystal says. “But now we are building a foundation for this approach to the treatment of anxiety disorders for the first time.” Source: Yale School of Medicine
The Beclowning of Scott Bessent
One iron law of current politics is that nobody who associates themselves with Donald Trump emerges with a shred of credibility. For some, that’s not a big loss — it’s not as if anyone respected Pete Hegseth even before he decided that the key to military success in an age of drones and AI was more testosterone. For others, however, the costs are real. I’m old enough to remember when Marco Rubio was widely considered a reasonable, thoughtful politician. Right now, however, my candidate for the biggest loser is Scott Bessent, the Secretary of the Treasury. Bessent started out with significant reputation to lose: When Trump selected him, this was the headline in the Financial Times: Jason Furman, Barack Obama’s chief economist, described him as a “credible Treasury secretary who has a real understanding of the global economy”. But Bessent has now transformed himself into the Baghdad Bob of bonds. Three weeks ago, after intervening (for reasons that remain somewhat unclear) to support the Japanese yen, Bessent boasted about his ability to move markets and dared investors to bet against his, declaring “I am the house now.” He then tried to push long-term interest rates down, buying 30-year U.S. Treasuries in a move some have compared to paying down part of your mortgage by running up your credit card balance. Here’s how that’s going so far: To get some perspective on how high interest rates have gone, here’s a longer-term perspective: We haven’t seen interest rates this high since the fading days of the dotcom bubble. Why are interest rates hitting new records? The backdrop, as I argued in last Sunday’s primer, is the huge AI-driven investment boom; more on that next week. But the immediate cause of the latest interest rate spike was Trump’s rejection of an Iranian proposal to end the war. This rejection sent crude oil prices, which for a while had fallen considerably, shooting back up: It’s notable, by the way, that oil prices remain high even though a significant amount of oil is now being shuttled through the Strait of Hormuz by night, on smaller vessels. That’s an interesting story, which has a lot to do with the fact that oil from the Hormuz shuttle runs must be transferred to larger vessels before being shipped to markets in Europe and Asia; around 15 percent of the world’s large crude carriers are now parked off the coast of Oman, waiting to be tanked up. This is creating a shipping crunch: But that’s a topic for another day. For now, the point is that with oil still high and refined products, especially diesel, still close to record levels, inflation will remain elevated. And this in turn means that the Federal Reserve will keep short-term interest rates high, an expectation that is feeding into longer-term rates. Hence Bessent’s bond-market humiliation. The truth is that Bessent might not have been able to get interest rates down even in the best of circumstances. But he certainly won’t get anywhere as long as Trump keeps believing that he can somehow convert his Iran debacle into a triumphant victory. And Trump will keep believing that as long as he is surrounded by sycophants who tell him what he wants to hear. Sycophants like, for example, Scott Bessent, who is predicting the imminent collapse of the Iranian economy, possibly within two weeks. Bessent is right to say that the embargo on Iranian oil exports is placing the country under great economic strain. But his implicit prediction that this will quickly produce a deal that Trump can call victory looks no more plausible than his boasts about the bond market. The big question now is, why would anyone with a reputation to lose work for Donald Trump? As the beclowning of Bessent shows, joining the Trump team won’t just damage your reputation; it will utterly destroy it.
Ken Welch's thorny Thursday showed exactly why he's about to join the club of one-timers
Projects delayed for retribution. Hiding from the press. Misuse of city resources. It wasn't just a bad day — it was a terrible one.
A Patient and Doctor Weigh the Pros and Cons of Genetic Testing
Genetic testing, a heart scan and a blood test gave Ron Carr unexpected answers about Alzheimer’s and cardiovascular risk.
Ultra-Processed Foods and the Aging Brain: What Does the Science Say?
Eating more ultra-processed foods has been linked to increased risk for dementia and Alzheimer's disease, as well as other non-brain health effects, including diabetes and cancer. But why do these foods affect our brain health?
Friends of BrainHealth grants advance dementia prevention and brain health research
For nearly 20 years, the Friends of BrainHealth donor circle has helped turn promising ideas into innovative brain health research.
Rare N2 dimer could let scientists answer questions about global ...
New technique could track how synthetic fertiliser use has disturbed ecological balance
Decoding Earth's magnetic field may help scientists treat Parkinson's and Alzheimer's. Here's how
"It passes through our bodies, our cells and every living organism on the planet, yet we know surprisingly little about whether and how this invisible force affects the way our cells work."
Angels Infielder Selects Free Agency After Year At Triple-A
Los Angeles Angeles infielder Jeimer Candelario was a Perry MInasian signing that didn't work out, so he's moving on.
Cowboys' Stephen Jones 'absolutely' supports Brian Schottenheimer after another miserable showing, 2-4 start
DIY VR: How to build your own headset, and why you probably won't want to
A primer on the joys and pains of building your own head-mounted display.
Your Brain Has Its Own Cleaning System That Helps Prevent Alzheimer’s. Science Is Learning How to Repair It
Your brain basically runs its own internal wash cycle while you sleep. Science is unraveling what happens when the system breaks down and how to fix it.
Find holiday decor and more at Autumn Leaves Craft Show
From holiday decorations to handcrafted dulcimers to one-of-a-kind finds, the two-day Autumn Leaves Craft Show has everything you need for a fun fall season. The annual show will be held
Brain health is focus on World Alzheimer's Day
Eli Lilly and Planet Harvest bring brain healthy food boxes delivered to seniors on Sept. 21, 2026 at Avon Tower in Rochester Hills, Mich.
Scientists Find a Hidden Network of Tiny Channels The Brain May Use to Flush Out Toxic Alzheimer's Proteins
Toxic proteins need an exit.
Your gut may be making a molecule that raises Alzheimer’s risk
Scientists have linked a gut bacterial compound called ImP to greater Alzheimer’s risk, harmful brain protein buildup, and faster cognitive decline. The finding raises the possibility that reducing ImP in the blood could one day help slow or prevent dementia.
Scientists Find a Hidden Network of Tiny Channels The Brain May Use to Flush Out Toxic Alzheimer's Proteins
Toxic proteins need an exit.
Brian Schottenheimer: "This Is a Business Trip"
Head coach Brian Schottenheimer discusses the Cowboys' preparation for their international matchup against the Baltimore Ravens, emphasizing the challenges posed by Lamar Jackson and Derrick Henry, the importance of communication on defense, and rookie Ja
Scarred blood vessels may be one clue to APOE4’s Alzheimer’s risk
Scientists know APOE4 raises Alzheimer’s risk. A surprising change in blood vessel cells may help explain how.
HHS Unveils Bold New Plan to Combat Alzheimer’s and Dementia
HHS announced the 2026 Update to the National Plan to Address Alzheimer’s Disease and Related Dementias.
The Angry Elephant politics-themed bar opens new location in Katy
The Angry Elephant, a politically-themed bar and grill, opened its third Greater Houston location on Westheimer Parkway in Katy on Oct. 19.
Dementia rates are high in Louisiana. These experts have tips to keep our brains healthy.
There are simple ways to reduce your risks of Alzheimer’s disease and other cognitive issues. Doctors share their advice for better diets, sleep and easy exercise.
Sondheimer: Midseason football report: Quarterback have been the big story
Chaminade High sophomore quarterback Jeremy Mellalieu has been among the most improved players this season.
When “DEI” research is cut, what happens to community health?
“I’m just going to run to the grocery store!” How many times have we said this without thinking about it? For most of us, it's usually an easy walk or a short drive to get the cheese we forgot. In reality, though, 13% of the U.S. population (about 39 million people) live in “food deserts,” which means living more than a mile from a grocery store in urban areas and more than 10 miles in rural areas. This was the case for people in Pittsburgh’s Hill District, where a quick run to buy food wasn’t an option. In the 1930s, federal maps marked the Hill as "hazardous" for lending, a practice known as redlining that steered investment away from Black neighborhoods. Decades of disinvestment followed, and residents went about 30 years without a nearby grocery store. This made it hard to keep healthy eating habits and contributed to chronic disease. When a grocery store finally opened in the area in 2013, researchers saw the opportunity and launched the PHRESH study, which initially compared the health of participants from the Hill district to those in the Homewood district. Over time, the study expanded to other factors such as brain health and Alzheimer's risk. Residents like Roderick Blair overcame initial hesitation to share their health data, trusting it would benefit their neighborhood. Then, in August 2026, the NIH abruptly canceled the study’s grant, citing that it was “subjective” and fell outside their scientific scope—an effect of the administration’s interpretation of diversity, equity and inclusion (DEI). Research like PHRESH can help determine what changes in a neighborhood actually improve health, so cutting it has left that question unanswered. Other canceled studies have examined health issues like maternal health, preterm birth rates, or sickle cell disease. Courts have reversed some of these grant cancellations, but not all of them. If we really want America to be healthier, research into why some communities get sicker than others is absolutely critical. The law that created the federal minority health research institute passed with bipartisan support in 2000. But these days, as evidenced by grant cancellations, the political shift in attitudes toward DEI means we often lose access to the health information we need to help all communities thrive. DEI vs. health equity vs. equality and the overlap (or lack thereof) The letters “DEI” evoke very different reactions depending on who you are in the U.S. DEI programs can address gender, disability, age, and other factors, but the fiercest debate centers on race. For some people, hearing DEI brings to mind policies that may have cost them a job or a college seat because they are white. Others see DEI as a matter of justice: a way to expand representation and opportunity for groups that have been historically marginalized. Both perspectives are rooted in lived experience, and both center on the same question: whether hiring and admissions practices are fair. Hiring and admission practices, though related, are not the same as health equity. Health equity is “the attainment of the highest level of health for all people.” It’s the recognition that some groups of people consistently experience worse health outcomes than others. For instance, black mothers die from pregnancy-related complications at three times the rate of white mothers, and rural Americans are more likely to die from issues such as heart disease and cancer. Equity is also often conflated with “equality,” which leads to misunderstanding of how to actually best support communities. Equality ignores the fact that we aren’t all starting life with the same resources or circumstances, whereas equity is about helping people get what they specifically need based on their situation so they have the chance to achieve the same outcome as anyone else. For example, if every household in Pittsburgh got a $30 grocery gift card, that would be equal. But during the decades the Hill District went without a grocery store, that card wouldn’t have helped much. Equity means making sure everyone can actually access a store in the first place. DEI policies can overlap with health equity in many ways. For example, they may help expand access to quality education and stable, well-paying jobs, which in turn can provide health insurance, safer housing, and improved finances—all of which can reduce health disparities. But to make that happen, we first need data to identify disparities in communities and to develop solutions that effectively address them. What we lose when the research stops Community data is important to health equity because: You can’t fix what you don’t see: Data show which communities are most affected by health factors such as infection, heart disease, and cancer. If we don’t know what is happening and where, then we can’t develop interventions to help. Poor health costs everyone: Chronic disease is expensive—both to the individual person and to the overall economy. Understanding what groups of people are most at risk allows us to develop interventions that can save everyone money. Disparities exist for many communities: Health equity includes disparities that exist due to a whole host of factors, such as family background, race and ethnicity, rural vs. suburban residence, gender and sexual orientation, veteran status, disability, and lower income. This means many Americans can benefit from research into differences in health outcomes and how to improve them. Trust is easy to lose: Some participants in the PHRESH study were initially vocal about their concerns about participating. But that trust was earned because the researchers kept their promises and centered their work on the community. When projects are canceled mid-cycle, researchers have no choice but to leave behind communities they had promised to help. This hurts trust in the long run. It’s also a very inefficient use of resources, and it will take significant time and effort to redo the work when the government realizes this work is important again. How should we talk about health equity? This is hard because the words “equity” and “DEI” are currently very politically charged. So whether you’re a public health professional, teacher, or friend, how we talk about this topic matters. The right framing can help people who might otherwise be skeptical see why health equity research is important and deserves funding. Here are some suggestions to help your conversations: Choose your words strategically: Who are you trying to reach with your message? Are they likely to be resistant to terms like “diversity” and “equity”? If so, find alternative words to use to still get the message across. It is frustrating to be in that position, but the goal of improving health is too important not to try to make inroads. Sometimes simply reframing can help the message reach those who need to hear it. Focus on the problem: The terms “health equity” and “DEI” are abstract. Make it more specific. For example, discuss differences in maternal death or ways to improve health outcomes in rural communities. These still have equity at their core but will likely be better understood by those you’re talking with. Focus on systems: Disparities exist, but if they are communicated poorly, people can mistakenly think the issue is the individual’s fault. Disparities are largely driven by failures of the system—such as lack of access to health care and a long legacy of racism. When discussing the disparities, frame them around these systemic issues to ensure blame isn’t placed on the individuals impacted. Tell stories: Personalize these policies by using stories from those impacted that connect to the data you’re trying to convey. This helps make the policies and outcomes more concrete and meaningful. Bottom line Some communities end up sicker than others. That’s just the facts. We can argue about the best way to do that research, but canceling it simply because it may be linked to DEI doesn’t make anyone healthier. It just leaves communities like the Hill district behind. And in the end, it causes us all to move backward in our efforts to improve health in this country. Love, EM Big thanks to MacKenzie Isaac & Legairre Radden, who reviewed this piece and generously shared their expertise and lived experience to help improve it. Dr. Liz Marnik, PhD, is Executive Director of The Evidence Collective and a science communicator and immunologist working at the intersection of public trust, science, and public health. To discuss communication training on topics like health equity and storytelling, email Liz at liz@yle.health or learn more on our website. Your Local Epidemiologist (YLE) comprises a team of experts, ranging from physicians to immunologists to epidemiologists to nutritionists, working together with one goal: to “translate” ever-evolving public health science so that people are well-equipped to make evidence-based decisions. The YLE suite of newsletters reaches over 475,000 people across more than 132 countries. This newsletter is free to everyone, thanks to the generous support of fellow YLE community members. To support the effort, subscribe or upgrade below: Your Local Epidemiologist is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Subscribe
Is metascience being co-opted?
In July, the White House released a report that argued academia is deeply dysfunctional and in need of radical reform.Science: A New Golden Age sets out a litany of problems many academics will recognise: interminable waits for grants; short-term funding rather than support for longer, more ambitious projects; ballooning administrative requirements; pressure to publish, and many more. “The scientific machine is getting bogged down,” it says. At least on the face of it, Science: A New Golden Age is a triumph for the metascience movement, a loose-knit, global group of academics, philanthropists and think tankers that want far more testing and experimentation in how we fund public research and innovation. The report tells US research funders to set up internal metascience units to do just this. But it has also set alarm bells ringing that metascience is being conveniently deployed to help justify the defunding of US universities, which US vice president JD Vance has openly labelled “the enemy.” “Just because you have an issue with your plumbing in your house doesn't mean you light the entire house on fire and burn it to the ground,” said Colette Delawalla, chief executive of Stand Up for Science, a group campaigning against what it says are attacks on scientists by the Trump administration. No one is arguing that academia doesn’t need reform, but there’s debate over how far and how fast the system should be shaken up. Does public R&D need slow and steady evidence-based adjustment, or radical new experiments?One of the key arguments in Science: A New Golden Age is that there’s not enough funding for what it calls “mid-level” science: engineering-heavy projects that require tens of millions of dollars, involve ten to a hundred people, and last around five years. Such a project might develop a brain-computer interface for people with Alzheimer's disease, for example. As such, the US National Science Foundation (NSF) has already announced $1.5 billion to set up so-called X-Labs, effectively new research organisations to pursue breakthroughs in areas such as quantum sensing and new scientific instruments. Funding divertedBut there’s a catch: this money has squeezed NSF budgets for more traditional, fundamental research grants, Science reported in June, likely meaning less cash for university-based scientists. Science: A New Golden Age also makes various swipes at universities, accusing them of extracting overheads from scientists to fund administrative bloat. “We have become dependent on a narrow set of legacy institutions,” it says. The report doesn’t mention it, but the US government is simultaneously seeking greater powers over federal funding, which would allow political appointees at funding agencies to screen or cancel research grants mid-project. The White House is also seeking to slash the NSF’s budget by more than half in 2027, although similar cuts proposed for 2026 were blocked by Congress. Convenient hookThis has worried some that the metascience agenda could be misused as a kind of smokescreen to further weaken universities. James Wilsdon, executive director of the Research on Research Institute at University College London, said that the report contains lots of “interesting ideas” and agrees that in places, academia is a “pretty broken system.” But the risk is that metascience is being deployed as a “convenient hook” to support cuts and a “political land grab” to transfer grant power from scientists to political appointees in US funding agencies.So far, the metascience agenda hasn’t been seized on by radical right parties in Europe. But Wilsdon worries it will cross the Atlantic, politicising research reform efforts and making them more difficult to carry out. The report is already making some in Europe sceptical of the entire idea. “The system is not without flaws, but the metascience discussion is not likely to improve the system but rather to generate munition to undermine it,” said Claes de Vreese, a professor of AI and society at the University of Amsterdam. Peter Thiel protégéOfficially, Science: A New Golden Age has just one named author: Michael Kratsios, the director of the Office of Science and Technology Policy and a former chief of staff to Silicon Valley mogul Peter Thiel. He also served as chief financial officer of Thiel’s Clarium Capital Management. Since the 1990s, Thiel has criticised US universities for moving away from teaching what he views as the classic works of western civilisation, and drifting towards “anti-Western zealotry.” And since 2011, he has offered two-year fellowships of $250,000 to young people to skip or drop out of university, and instead start companies or pursue scientific research. “College can be good for learning about what’s been done before, but it can also discourage you from doing something new,” according to the Thiel Fellowships website. In other areas, the Trump administration has promoted academics with a longstanding interest in metascience. For example, the head of the National Institutes of Health, Jay Bhattacharya, in 2020 co-authored a study arguing the funder backs overly conservative proposals, although he achieved wider prominence as a critic of pandemic lockdowns. Careless talk costs fundingEven before the Trump administration embraced the metascience agenda, some metascientists privately wondered whether they should be careful not to overstate dysfunctions in academia, in case this gets used as ammunition against universities. But others think being cautious with criticism is pointless. After all, last year, the Trump administration sought to cut funding from US universities on an entirely different premise: supposed antisemitism on campus. “I don't think these governments need a technical metascientific excuse to attack the universities, they will want to do so anyway,” said Will Stone, a researcher at Science Works, a new think tank advocating for a “metascience revolution” in the UK. “I think researchers should report what they find, even when the findings may be used to advance policies they disagree with,” echoed Russell Funk, a researcher at the University of Minnesota, who in 2023 co-authored a highly influential paper that argued scientific papers were becoming less disruptive over time. No justificationThat said, Funk thinks that metascientific research certainly doesn’t justify a weakening of universities. Instead, scientists need “time, resources and stability to pursue unfamiliar ideas,” he said. “Taking away those conditions works against the very goal the reforms are supposed to achieve.”The Institute for Progress, a Washington DC-based innovation policy think tank that has championed X-Labs and metascience units, also says that reforms should complement, not supplant, universities. “Unpredictable, unreliable, and reduced federal funding to researchers is destabilising to the very foundations of research and development and is bad,” said Jenn Gustetic, the institute’s director of metascience and R&D policy.Evolution or revolution?This points to a much bigger divide in the metascience community: how far and how fast should public R&D be shaken up? Does it need evolution or revolution? For example, Science: A New Golden Age says the science system relies too heavily on traditional “workhorse” project grants, the type that pay out around $250,000 a year to fund “hypothesis-driven science by small teams on tractable questions.” However, in criticising project grants, the report “decisively picks one side of a debate that is far from settled,” David Hilmer Rex, a metascientist based in Denmark, has written. In June, Pierre Azoulay, a metascientist at the Massachusetts Institute of Technology, defended project grants, saying that the alternative of X-Labs “merits scepticism.”A-B testingOne challenge in metascience is that it’s easier to generate evidence for some types of change than others. Most straightforwardly, research funders can run A-B tests on different ways of awarding money. For example, Germany’s Volkswagen Foundation recently trialled distributed peer review, where applicants rate each other’s proposals, and measured its results against traditional review panels. Distributed peer review made quicker decisions, although awarded money to largely different ideas. However, much of the focus of the metascience movement has been on founding fast-moving and free-acting new research organisations and funders, in contrast to the alleged stodginess of mainstream academia or public innovation grants. A culture of speed and freedom are the animating principles behind Germany’s Sprind or the UK’s Advanced Research and Invention Agency (Aria).Related articlesViewpoint: it's time to experiment with how Europe funds science European researchers sound the alarm that Trump rule changes will hit cooperationHowever, while it’s possible to closely study previously successful bodies, such as the US Defense Advanced Research Projects Agency (Darpa), for historical clues to their secret sauce, it’s impossible to guarantee in advance that the likes of Sprind or Aria will actually work as hoped. But advocates of new organisations say this inherent uncertainly shouldn’t stop us trying. “If we wait for definitive proof that something will work before we try it, I don't know where your proof is coming from,” said Stone. Trade-offsUp until now, experiments in metascience haven’t generally come with hard trade-offs over money. In the US, new ideas such as focused research organisations have often been funded by billionaire philanthropists. In Europe, new innovation agencies such as Sprind and Aria, or the Netherland’s new National Agency for Disruptive Innovation, haven’t needed explicit cuts elsewhere in the research system. But with the $1.5 billion establishment of X-Labs by the NSF, the trade-offs are becoming clearer. Some metascientists privately wonder whether a smaller pilot would have been more appropriate, given that the idea is untested. The Institute for Progress counters that the $1.5 billion X-Labs budget is spread out over a decade, so will account for less than 2% of the NSF’s annual budget. “It’s important to remember that [Darpa] was once an institutional experiment as well. Now it’s one of the most cited innovative funding models in the world,” said Gustetic.As for Europe?The US isn’t the only country placing metascience at the heart of its research strategy. Science: A New Golden Age looks admiringly at the UK, which in 2024 set up a Metascience Unit to scrutinise how it funds research. In Brussels, it’s more of a mixed picture. In 2018, the EU set up the European Innovation Council to funnel grants and equity to start-ups, although it’s sometimes criticised for awarding money too slowly. Recently, the council has started experimenting with challenges, where teams of inventors compete to overcome a technological challenge. The European Commission also wants to experiment with partially randomising grant winners, to cut down on bureaucracy. However, the Commission’s own advisers have said the EU’s own research schemes are too conventional. They want the Commission to establish a new dedicated unit to scrutinise and experiment with funding. But there’s no sign of a such unit emerging in Brussels’ plans for the next Horizon Europe programme, which from 2028 is set to distribute more than €160 billion over seven years. Sam Bogerd, director of breakthrough innovation at the Brussels-based Arq Foundation, an AI-focused think tank that also looks at metascience, says that Europe might have the opposite problem to the US: universities and basic research funding are still reasonably well supported, but there’s not enough experimentation. “We're not taking a close enough look at where this money can achieve the most, and I am worried that the good ideas around metascience will be tainted politically by their association with the Trump administration,” he said. He’s still lobbying for the Commission to set up an experimental unit. But in the meantime, the Arq Foundation plans to do its own research, and is currently hiring two metascience researchers to run the rule over how Brussels spends research funding.
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E.J. Willis Co. was founded in New York City in 1888 and for generations it has made ship’s bells and other equipment for the U.S. Navy and American shipbuilders. This summer, the new owner moved the company’s equipment to Fulton By Stefan Yablonski E. J. Willis Co. cast brass ship’s bells — handcrafted in the United States since 1888. Ship bells, “built to last a lifetime at sea,” are now manufactured in Fulton. E.J. Willis Co. has moved its operation and manufacturing business to Fulton. They are currently operating out of N.E.T & Die. The company is now under the ownership of Jonathan Hyatt. He recently acquired the company after seeing a for sale note on Craigslist. [caption id=attachment_11110 align=alignright width=400] Entrepreneur Jonathan Hyatt is the new owner of E.J. Willis Co. He bought the business this summer after finding a listing on Craigslist by chance.[/caption] “I had been looking for something to do. I had been 20 years in corporate America and I was just tired of building someone else’s empire, you know what I mean? I was in consulting, pretty much a jack of all trades. I wanted to do something that I could call my own,” he explained. “I’d been on this path of trying to find a business to buy for about a year. One night I am on Craigslist about 11:30 in mid-April searching for something completely unrelated. At the bottom of Craigslist was a ‘things you might be interested in from outside of your area.’ There was an ad that said 138-year-old bell manufacturing company for sale. So, I clicked; why not, right? I wasn’t looking to buy a manufacturing company, but I went down the rabbit hole, absolutely fell in love with the history and ended up buying it.” He read the ad and responded. “I called and I am talking to the owner of the business for about two hours. We ended with, let’s have another chat and then come on out here and have a look. I figured, well I might wind up getting kidnapped and getting murdered or there is a real business here. But I gotta see it through,” he quipped. “And sure enough, there is a big machine shop operation there. The gentleman who owned it was retiring and in the corner of this shop is a little room where they make bells and they have been doing this ever since the company had started.” That’s the one constant thing that has survived the changes of the business. [caption id=attachment_11061 align=alignright width=300] Sales 1929 general catalog published by E. J. Willis Co, listing all the merchandise it sold. It’s like the Sears Roebuck and Co. catalog for marine parts.[/caption] “I drove home and told my wife, ‘This is what I am doing for the rest of whatever we are calling this — mid-life crisis.’ And she said, ‘absolutely you got to do it.’ I took out a loan and off we go.” He put in an offer on the business and they closed on July 1. He didn’t disclose what he paid for the company. “In terms of price, the seller and I have agreed to keep those terms private.” “I am finding that I am a business owner, an archeologist, opening files and cabinets that haven’t been opened in 100 years. It’s just amazing, just cool things that I am finding,” he said. “I want to build the business back. I want to be able to sell the bells to outsiders. I think they are beautiful. “It’s really a wild story about a company that started in lower Manhattan, exploded in the automotive space, sold parts to the Wright Brothers, moved into the aeronautical world and then landed in marine. The cool thing, I have been digging around and the gentleman who owned the company prior to me was not a digital guy. There is nothing out there. “Now I am sitting here with all the art from like the 1930s, the E.J. Willis boat catalog it’s like 250 pages of things this company used to make. It’s like the Sears-Roebuck and Co. catalog for marine parts. We are modernizing, we are staying true to the heritage of the business. It’s exciting to be the next steward of the whole business.” Initially he thought he’d move everything from the company’s plant in Middleville, Herkimer County, to Boston, out of convenience. “Then I thought let’s keep the foundry where it is. Let’s not move anything right away,” he said. “I want to get a good sense of what we’ve got, what works and what doesn’t. “I went to the foundry and met with the people there, lovely people, and said here is my position — I am buying a company where everyone is retiring. There is machining and polishing to be done, who would you work with around here? Without hesitation they said, ‘you need to go to NET Tool & Die and talk to Michelle [Shatrau]. She is a third-generation machinist and she runs the company now.’” So, he drove to Fulton. “I knocked on the door, they let me in. And she said, ‘how’d you get in here?’” he said with a laugh. “We became fast friends. I told her what I am doing. It must have struck a nerve. She has a very entrepreneurial background. I must have said something right because she came out and she said, ‘I’d love to help you. Why don’t we move the equipment that you have into my large building and I will give you a space to work at and use my team?’” [caption id=attachment_11058 align=alignleft width=300] Bell in progress awaiting assembly[/caption] It’s a great relationship so far. “We are bringing the business into the modern world. It’s been a lot of stuff all at once. But it has been very exciting,” he said. “We moved in a month ago [in July]. We closed on the business July 1. We moved a couple weeks later. We had all our equipment set up, electrical being run, everything. [caption id=attachment_11059 align=alignright width=300] Bell attached to a lathe going through the machining process[/caption] “We’re working with NET Tool & Die to rebuild production and preserve manufacturing processes that, in some cases, existed mostly in the heads and hands of the people who had been doing them for decades. We’re currently working on several 200-pound ship’s bells and bringing an old two-way manual bilge pump back into production.” He said he will be working with NET employees for the time being, adding, “I’d love to get to a point where I have so much growth that I need to hire people.” No one wakes up and says, ‘I am buying a bell today,’ Hyatt admitted. [caption id=attachment_11060 align=alignleft width=225] Bell after receiving a custom etching toward the bell mouth[/caption] “Everyone does wake up and has things that deserve acknowledgment and remembering — a promotion, a marriage, the birth of a child,” he said. “These are the things I feel like if there was something that could capture a particular moment in time and will literally outlast the person that bought it, a bell is that. We can engrave a bell if you get married or the birth of a child. We can put anything on a bell. “I have orders, yes. I am working on several orders right now. We have a little bit of busyness. But there are still some things to work out. I want to make things consistently and continue to move forward.”
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