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Indigenous Biz Con explores a renaissance in Tribal business, technology and entertainment
Indigenous Biz Con returned for its fifth year Oct. 11-13, bringing Indigenous leaders, entrepreneurs and community members to Milwaukee to explore a potential economic renaissance for Indian Country. The annual conference, held at Potawatomi Casino, featured discussions on the current state and
On Violence in Fighting Occupation: The Case of Palestine
In this new postscript to various translations of his book on the Gaza genocide, Achcar addresses the role of violence in anti-occupation struggles.
Rethinking discovery: how powerful screening tools are redefining the search for new medicines
In medicine discovery, identifying the right biological target has always been a critical and complex step. Today, the rise of powerful screening tools is fundamentally reshaping this process, creating a step-change in how we move from scientific hypotheses to transformative medicines. Advances in high-throughput screening, genomics and AI-driven analytics are enabling scientists to interrogate disease biology at unprecedented scale, bringing forward opportunities that were previously beyond reach.
Nvidia establishes Israeli research group focused on AI for medicine and science
The Applied AI Architecture group has begun recruiting researchers in Israel and will work on AI applications ranging from genomics and drug discovery to new materials.
How we build genomic sovereignty in the Arab world
Genomic medicine is being built from datasets that don't represent the Arab region, although it has the talent, data and infrastructure to close the gap.
Quechan filmmaker explores Native sciences in PBS 'NOVA' episode
The PBS science series "NOVA" will explore Indigenous sciences and how traditional ecological knowledge has nurtured biomes and ecosystems, developed navigation systems using the stars and seas and domesticated foods now consumed worldwide in a new episode featuring Navajo hogan builders and created by a Quechan filmmaker.
Google DeepMind's latest AI tool promises a new era for genetics research, but experts warn to take its predictions with caution
AlphaGenome Atlas could make it easier for geneticists to access powerful AI, but its predictions aren't always accurate.
Coach says Ireland will fulfil second Israel fixture
Republic of Ireland manager Heimir Hallgrimsson has confirmed his side will fulfil their second Nations League fixture against Israel on Sunday, insisting he must “focus on football” amid ongoing protests. The Stop the Game campaign group in Ireland has called on fans to meet at the Aviva Stadium ahead of the home game against Austria on Thursday to voice opposition to fixtures which it says help to “sportswash genocide.
How Harvard scientists built genomics outpost on Gloucester harbor
It started with idea to help beleaguered fishermen. Now marine science lab promotes healthy fisheries, trains local workforce, seeks clues to longevity
New sensor developed at Oregon State shows promise for fast, low-cost food-quality testing
CORVALLIS, Ore. – Researchers in the Oregon State University College of Science have developed a new electrochemical sensor for rapidly and accurately detecting a naturally occurring compound widely used in the food, beverage and fragrance industries.The compound is eugenol, which gives cloves their telltale flavor and smell, and measuring its presence in commercial products is important for manufacturers and regulators.
10 years of Jackson Lab science shows the lifesaving power of genome-matched cancer treatment
These treatments have already changed the lives of Mainers battling the disease. Thankfully, more work lies ahead.
A 3,700-Year-Old Virus Hiding in a Medieval Book Just Killed 500,000 Animals
Holy manuscripts preserved the genome of a plague that wiped out up to 90% of Europe’s historical sheep herds.
Penguin Colony Developers Talk The BDS Talk And Walk The Walk By Banning The Game For Sale In Israel
The game also gives you one hell of a statement on the Palestinian genocide
Genoa 2-1 Fiorentina: Match report
The Viola can’t even score their own goal as they slump to a deeply embarrassing defeat against a bad opponent.
Alaska Beacon reporter recognized with national science journalism award
Alaska Beacon reporter Yereth Rosen’s award-winning science story weaves together regional indigenous knowledge, scientific study findings and political influences to answer a freighted question about the future viability of village life in Western Alaska after ex-typhoon Halong.
Celebrating Indigenous Peoples Day in the Face of Political Erasure
Overview: Indigenous Peoples’ Day offers an opportunity to recognize and celebrate Native peoples, confront historical revisionism and ongoing efforts to erase Indigenous contributions, and promote greater understanding of Native history, cultures, and sovereignty. Guest Opinion Falling on the second Monday of October, Indigenous Peoples Day is a chance to collectively celebrate the history, cultures, and […]
Mahony named Huck Chair in Genomics and AI
Shaun Mahony, professor of biochemistry and molecular biology in the Penn State Eberly College of Science, has been named the Dorothy Foehr Huck and J. Lloyd Huck Chair in Genomics and AI.
Commission announces plan for polar hub to step up research coordination
The European Commission plans to develop an EU polar research hub to strengthen coordination and improve the alignment between science and policy. The objective, according to a Commission official, is to “better connect research, observation and scientific infrastructure, improve access to research resources and strengthen coordination with stakeholders, including Indigenous people.”Announced in a new EU Arctic strategy on October 20, there is little detail yet on how the hub will be implemented, only that it will “reinforce and expand” the European Polar Coordination Office (EPCO), which is hosted and managed by the European Polar Board (EPB) at Umeå University in Sweden. EPCO was born from the EU-PolarNet projects funded through Horizon 2020 and currently coordinates the EU Polar Cluster, a network of EU-funded collaborative polar projects.While the practical details remain to be defined, the decision sends “a clear and positive signal,” said Maria Grigoratou, head of EPCO and executive secretary of EPB. “By reinforcing EPCO, the Commission has an opportunity to build on the legacy of EU-PolarNet 2, strengthen European polar research coordination and expand cooperation with a broader range of Arctic stakeholders,” she told Science|Business.The move has been welcomed by the polar research community. “The polar research hub could play an important role in connecting existing research communities, observation systems and infrastructure, and in bringing scientific knowledge closer to policymaking, in cooperation with local communities and Indigenous people,” said Katrine Moland Hansen, director of operations at Norway’s Nansen Environmental and Remote Sensing Center.But money will be an issue. “It is clear that EPCO will need more resources and structure to function well and to make research reach policymakers,” said Kati Lindström, vice-chair of the Polar Research Committee of the Estonian Academy of Sciences. “European polar research is big if we pool the resources, and it should not only be left to enthusiastic scientists to develop networks of strategic importance in their free time.”The Arctic strategy makes a point of saying that local communities should have a greater involvement in Arctic science. “All EU Arctic research consortia are mandated to invite Indigenous people representatives to participate in projects,” it reads. “The EU also supports research that is directly led by Indigenous communities and address their challenges.”It also underlines the importance of reinforcing collaboration with like-minded partners such as Norway, Iceland, Canada, the UK, Japan and South Korea, as well as deepening its engagement with NATO. This includes the US, with which “the EU is committed to continuing a pragmatic transatlantic engagement based on shared interests and values.”Related articlesViewpoint: Does Europe dare to invest in the Arctic?Anchor Greenlanders in Arctic climate research, experts tell EU ahead of policy updateFor Moland Hansen, this open and inclusive approach to cooperation is encouraging. “The Arctic is also a strong example of why equal participation of associated countries in EU funding instruments matters.”Overall, she finds the new Arctic strategy to be ambitious, timely and comprehensive. “We particularly welcome the recognition that climate change, environmental protection, security, resilience and competitiveness are closely interconnected,” she said. “Research, observations and forecasting capabilities are essential to understanding the rapid changes taking place in the Arctic and addressing these challenges together.”Security focusWhile the Arctic strategy foregrounds security, with pledges to protect undersea cables, boost satellite monitoring, deploy more icebreakers and improve military mobility, the polar community is satisfied that environmental concerns have not been forgotten.“It is inevitable that there is a strong security angle to the EU Arctic strategy, but the impact of climate change and need for climate mitigation and resilience is also strongly recognised and includes a pledge to stay the course on climate commitments,” said Sian Prior, lead advisor to the Clean Arctic Alliance, a coalition of campaigning non-profit organisations.“We need to remember that by the time the next Multiannual Financial Framework comes to an end, in 2034, the polar regions, especially the Arctic region, will be living under a new reality when it comes to ecosystem processes, when it comes to the climate,” Grigoratou went on. “And that will affect any ambition that humans may have in the region.”Lindström agreed. “All aspects of European security are dependent on climate change in the Arctic and consequently, on climate science,” she said. “We cannot close our eyes to issues like energy security, critical minerals, northern shipping routes, dual-use technologies and others. However, it remains to be seen how well the promises to protect the environment and Indigenous rights will hold when faced with critical mineral extraction under the Critical Minerals Act.”
Is Indigenous Knowledge Science? Understanding Indigenous Science ⋆ The Costa Rica News
Explore Indigenous science, Indigenous knowledge, and Western science through Sarah Lynn Thomas’s reflections from the World Ayahuasca Forum.
Scientists Uncover Gravity’s Impact on the Human Genome
Researchers build microgravity simulator to illuminate how external forces affect our cells
GenomeWeb Best Places to Work Winner (101-250 Employees): Health Advances
Life science consulting company Health Advances has won GenomeWeb's Best Places to Work award in the 101-250 employee category.
Three years into Gaza’s genocide, U.S. political rhetoric hasn’t translated into action
While some political candidates rose to prominence through their support for Palestine, the U.S. has not stopped backing Israel
Life Science Tools Market Forecast to 2035: Growth Accelerates on Genomics and Biomanufacturing Demand
The global life science tools market is forecast to expand through 2035, supported by rising genomics research, biomanufacturing scale-up, and lab automation adoption.
Scientists reconstruct face of man who lived in Ecuador 3,000 years ago
Skulls discovered in Ecuador's Andes fueled theories about the origins of ancient Americans; a new facial reconstruction supports an Indigenous ancestry, but researchers say DNA testing is needed to settle the question
Tribal-owner business launches beer for a good cause
Thurston County tribal-owner business Talking Cedar is launching a seasonal beer with a goal of bringing awareness to missing and murdered indigenous women.
Study reveals evolutionary history of bats, dating back 65 million years
Researchers assembled the largest collection of high-quality bat genomes to date
NSF backs research collaboration to sequence Antarctic genomes
The National Science Foundation (NSF) has awarded $18.4 million to a group of scientists producing an extensive genetic database of Antarctic lifeforms. More than 250 Antarctic species’ genomes will
Labcorp to Acquire Select Assets of BioReference Health for $722M
Labcorp will acquire BioReference's lab businesses focused on clinical and women's health testing, urology, and corrections as well as its 4Kscore prostate cancer blood test.
SKC builds new generation of Indigenous leaders with national business chapter
It's the first week of classes at Salish Kootenai College for the fall semester. As class lets out, students, new and returning, are making their way into the John Peter Paul building for the first meeting of an important club on campus. This club gives students hands-on experience by inspiring Indigenous students with leadership, networking, scholarships and business experience.
Indigenous culture, contributions celebrated at Rochester Museum and Science Center
The Rochester Museum and Science Center celebrated Indigenous Peoples’ Day with traditional dances, crafts and educational activities highlighting Indigenous culture. https://www.rochesterfirst.com/community/indigenous-culture-contributions-celebrated-at-rochester-museum-and-science-center/
Scientists Kept Finding The Same Mysterious DNA In Their Samples. The Marine Microbe It Belongs To Has The Smallest Genome Ever Identified
This tiny marine organism may demonstrate just how little genetic material a cell needs to survive.
Netanyahu, Mamdani reignite feud ahead of U.N. General Assembly
Mamdani has called Netanyahu “an architect of a horrific genocide.”
Genoa vs Fiorentina: Lineups and how to watch
The Viola remain as unpredictable as ever as they emerge from the break.
Beyond the textbook: Bringing real science into the classroom
Forget baking soda volcanoes! Some high school students are getting hands-on experience with real genomic research. We talk with educators about how partnerships with working scientists are bringing cutting-edge science into the classroom.
‘Enormous potential’: UK envoy seeks deeper Israel ties in science, technology and trade
Ambassador Simon Walters tours the Oxford-Cambridge Growth Corridor, meeting researchers, investors and industry leaders as Britain seeks new partnerships with Israel in genomics, life sciences, agri-tech, AI and clean tech despite political differences
Indigenous Biz Con explores a renaissance in Tribal business, technology and entertainment
Indigenous Biz Con returned for its fifth year Oct. 11-13, bringing Indigenous leaders, entrepreneurs and community members to Milwaukee to explore a potential economic renaissance for Indian Country. The annual conference, held at Potawatomi Casino, featured discussions on the current state and
African genomics research is growing: what countries are doing to connect genetic data and healthcare
National genetic projects are important but they must have local expertise, responsible data governance and sustained investment to improve healthcare.
GenomeWeb Best Places to Work Winner (26-50 Employees): Genomate Health
Genomate Health, a Cambridge-based computational oncology company, has won GenomeWeb's Best Places to Work award in the 26-50 employee category for the second consecutive year.
It took 3.7 billion years for this genome to evolve. UF students assembled it in one semester
Key points Eleven undergraduate students at the University of Florida are the first to assemble the pignut hickory tree genome. The work was done as part of a hands-on research course open to all majors and taught by instructors at the Florida Museum of Natural History. The hickory tree s
African genomics research is growing: What countries are doing to connect genetic data and health care
Much of what scientists know about how genetic differences affect health comes from studying populations outside Africa. This matters because genetic information is increasingly being used to understand ...
Sanford Health in Bemidji Recognizes Indigenous Peoples Day
https://youtu.be/8efUyxgqZdI Indigenous Peoples Day was celebrated at Sanford Health in Bemidji with a blessing and prayer to start the day, serving a community bison roast and wild rice lunch, and learning about the history of jingle dresses from Vicky Fineday.
Race for Tarrant County judge a barometer of region’s political dynamic, analysts say
ncumbent Republican Tim O’Hare faces Democratic commissioner Alisa Simmons in the race for Tarrant County judge.
A record number of Native Americans are running in the 2026 midterms
At least 355 Native American and Indigenous candidates ran or are running in local, state and federal primary and general elections this year — a record number.
How Technology Is Quietly Reshaping the Beef Business
Remote water monitoring, digital herd records, genomic selection and virtual fencing are moving from buzzwords to bottom‑line tools. But survey data shows most producers still leave money on the table by delaying adoption.
Geno Smith Bluntly Bashes Titans Defense
Despite heavy off-season investment, Tennessee’s pass rush failed to pressure the veteran quarterback, leaving the defense reeling as they prepare for a formidable Philadelphia offensive line.
7 extraordinary Indigenous sites in the US, from Chaco Canyon to Chimney Rock
The Native Americans built impressive sites across what is now the U.S., including Walnut Canyon and Cahokia.
Ms. Rachel stirs controversy with 'genocide' post amid Gaza war
Ms. Rachel may be a star, but she has bigger priorities than Hollywood.
Who Is Indigenous? The Politics of Tribal Identity Terminology in India and Bangladesh
Tribal people in South Asia prefer being called adivasi or original inhabitants, but nationalist forces in India and Bangladesh oppose it for different reasons.
Making gene-edited babies is illegal. This startup says it may be time to reconsider
Origin Genomics aims to prove the potential benefits of its technology for editing disease-causing genes in human embryos outweigh the risks.
From wild rice to tarwi, researchers are exploring the health potential of Indigenous foods
A conference paper reviewed North American and Andean Indigenous foods, including Three Sisters crops, wild rice, native berries, tarwi, quinoa, and amaranth, and described their nutrients and bioactive compounds. Evidence for health effects remains limited for many of these foods, and the authors call for research developed with Indigenous communities that also supports traditional knowledge and food sovereignty.
Troy Jackson apologizes for remarks about Jewish Maine residents’ views of Gaza war
Troy Jackson, the Democratic nominee in Maine’s battleground Senate race, apologized Wednesday for saying it is “unfortunate” that Jewish residents of the state do not like to label the war in Gaza a genocide.
Science on Target: Q3 Research We Conduct
The Target ALS Global Natural History Study (GNHS) is entering a new phase of discovery. As the only international, longitudinal study generating deeply characterized clinical, genomic, and biofluid data to accelerate ALS biomarker discovery and therapeutic development, the GNHS is now beginning to deliver large scale datasets and resources needed to support new insights into […]
Bessent mocks Sen Warren, wishes her 'Happy Indigenous Peoples' Day' in response to letter
Scott Bessent accused Elizabeth Warren of having little knowledge about financial markets in a snarky response to her 10-year treasury yield letter.
Yale School of Medicine On the Science of Childhood Anxiety, Say, Anxiety Disorders Are the Most Common Mental Health Challenges In Youth
Credit: Matt Bradbury October 5, 2026 - By Isabella Backman - Anxiety disorders are the most common mental health challenges in youth. Left untreated, they can disrupt the lives of both children and their families. The good news is that with intervention, most children will overcome these conditions. Across Yale School of Medicine, scientists are working to understand anxiety at every level, from common anxious behaviors to molecular biomarkers in the brain. They are using their findings to develop and disseminate new evidence-based treatments for childhood anxiety. Today, the go-to treatment for childhood anxiety disorders is cognitive behavioral therapy (CBT). This is a form of psychotherapy that teaches children skills for confronting anxious thoughts and helps them practice managing situations that cause anxiety. While it is the gold-standard treatment backed by considerable scientific evidence, up to 50% of children will not see sufficient benefit from CBT alone. Wendy Silverman, PhD, Alfred A. Messer Professor in the Child Study Center, co-directs the Anxiety and Mood Disorders Program alongside Eli Lebowitz, PhD, associate professor in the Child Study Center. One of their main interests is learning how to improve outcomes beyond CBT. “We’re developing cutting-edge, research-based knowledge that can reduce the suffering that anxiety causes children and their families,” says Silverman. Changing parent behavior YSM experts are investigating how to improve CBT outcomes for children by involving the parents. Silverman’s research has uncovered two main components of parent intervention that improve childhood anxiety: not enabling children to completely avoid the things that make them anxious and taking steps to enhance their autonomy. Parents may unintentionally reinforce their child’s anxiety by allowing them to avoid what makes them anxious. They also may unintentionally limit the children’s sense of autonomy by being overly intrusive. “One of the things that we take pride in is that we’ve focused on trying to understand what parents need to do, and to test our ideas and see if changing the parents’ behaviors is enhancing the effects of CBT,” Silverman says. “Our findings thus far suggest that they do." As much as CBT can be helpful, it can also be challenging to get one’s child to do the necessary steps for CBT to work. This is one important reason why Lebowitz created a novel intervention program for parents named Supportive Parenting for Anxious Childhood Emotions (SPACE). Existing intervention programs often teach parents to act as therapists for their child, such as training them on how to practice breathing exercises. “It makes sense, but this doesn’t work very well in practice,” says Lebowitz. “And part of the reason, I think, is that it’s not easy to get your kid to do things, especially if they’re not excited about doing it.” SPACE is unique because it focuses entirely on parent involvement and changing parental behavior—children are not involved in the sessions. For example, parents learn how to use supportive messages that convey confidence that their child can tolerate and manage distress. “It might sound like a parent saying to a child, ‘I get that this is really hard for you, but I know that you can handle it,’” Lebowitz says. The program also works with parents to identify the ways in which they are accommodating anxious behaviors. “We’ll pick one thing that parents are doing that is an accommodation and help them make a detailed plan for how they’re going to change that,” Lebowitz explains. Treating Anxiety in Children and Adolescents Much of the existing research on SPACE has focused on parents of children under age 14. Ongoing studies are now exploring its use with parents of older teens. “Both anxiety and accommodation can interfere with normative developmental shifts during the teen years, including increased autonomy and individuation from parents,” says Rebecca Etkin, PhD, associate research scientist in the Child Study Center. “In this sense, SPACE may be particularly well-suited for anxious teens and their parents. We want to see whether it is effective during this distinct developmental window.” Unfortunately, many families in need of CBT face barriers, including limited availability of services and geographic constraints. One way to improve access is digital interventions. Silverman and her team are developing an evidence-based digitized intervention program for parents that they can access directly from their computer or smart phone. “The work we’re doing will be one of the very few parent interventions that is digitized and importantly tested for effectiveness,” she says. Creating interventions for anxiety-related challenges Silverman and Lebowitz recently received a generous gift to develop and test other interventions that help parents reduce other child anxiety-related behavioral and emotional difficulties, such as restrictive eating and unexplained somatic symptoms. One of these projects in particular focuses on understanding the risks of social media and its potential benefits, including offering a sense of connection. “A lot of research has focused on the idea that social media is harmful and the less of it the better,” says Lebowitz. “But we actually see is that this is not quite right—there are negatives, but there are also positives. So, we’re trying to get a little bit more nuanced of a picture.” The team is working with teens with social anxiety and their parents over an extended period to better understand their social media habits and how their anxiety levels affect engagement with different platforms. The teens will answer questions sent to an app on their phones about mood and social media usage in an effort to capture emotional responses as they unfold. “We hope to develop interventions that can help make the best of social media while protecting against the more problematic effects,” Lebowitz says. The brain’s role in anxiety Researchers are also testing therapies to address anxiety at the neurological and molecular levels. In collaboration with Dylan Gee, PhD, professor of psychology in Yale's Faculty of Arts and Sciences, and Hilary Blumberg, MD, John and Hope Furth Professor of Psychiatric Neuroscience at Yale School of Medicine, Lebowitz and Silverman are using brain imaging to identify changes in a child’s brain before and after parents enroll in SPACE. In one study, children viewed anxiety-inducing images while undergoing magnetic resonance imaging (MRI); the researchers conducted scans with and without the children’s parents nearby. Before SPACE, children’s brains were better able to activate the regulatory circuitry needed to turn off an anxious response when their parents were nearby. But after SPACE, children could activate this circuitry even without the parent around. “As parents work on gradually reducing some of their accommodations, you can see a child get better at regulating their own fear system in the brain,” Lebowitz says. “It’s remarkable.” Research into the molecular underpinnings of anxiety can also inform new childhood anxiety treatments. In a recent study, Lebowitz, Silverman, and Flora Vaccarino, MD, Harris Professor in the Child Study Center, discovered that a protein known as fibroblast growth factor 2 (FGF2) could be protective from the toxic effects of stress. FGF2 levels in children and their parents were linked to the children’s risk of developing anxiety and depression, the study showed. The findings could help explain why some children who are exposed to early life trauma such as poverty or abuse are more prone to developing mental health disorders. And FGF2 could be a target for treatment. “This is very novel because it starts to give a clue to what is the molecular chain that connects those lived experiences to the actual psychological outcomes,” Lebowitz says. New ways to study and treat childhood anxiety Michael Crowley, PhD, associate professor in the Child Study Center, collaborates with Silverman and Lebowitz to study the role that attention plays in development and maintenance of childhood anxiety. There is a large body of research that shows that anxious children, like anxious adults, are prone to focus on threatening stimuli such as angry faces compared with neutral faces. This has led to innovative interventions that involve attention retraining. The idea is that if experts train children to look away from threatening stimuli, it may reduce their anxiety—especially children with social anxiety who are most prone to attend to threats. The researchers have just completed a clinical trial for attention retraining with 10- to 14-year-olds with social anxiety disorders and are currently analyzing the findings. Besides this innovative attention retraining research, as Crowly notes, “I like to design tasks that are engaging to kids,” Crowley says. “My goal is to assess something without the kids knowing what we are assessing.” With this goal in mind, Crowley has created a virtual game, named Boom, to study threat processing in children with anxiety disorders. The game is similar to that of hot potato—the child and three digital players take turns virtually passing a ball to each other’s gloves. At some point, the ball turns into a bomb, and as the bomb lands in each player’s glove, the outline of the glove turns yellow. The goal is to avoid having the bomb go off in your glove. What isn’t obvious is that the game is designed to measure different types of threatening stimuli, both ambiguous and direct. In the game, the direct threat occurs as the bomb is traveling towards your glove. The ambiguous threat is the yellow outlined glove as it is unknown where the bomb will travel next. While children play the game, Crowley’s team measures their brain activity using electroencephalography (EEG). The researchers have discovered that in kids with anxiety, the brain reacts more strongly to ambiguous threats than it does in their peers, but less strongly to direct threats. They believe that the initial abnormally large brain response to not knowing where the bomb is going impairs the brain's ability to properly respond when the threat is actually traveling the child’s way. “The brains of children with anxiety are unable to differentiate between threats you need to do something about and those that are not your problem.” Michael Crowley, PhD, develops innovative games for studying anxiety in children and adolescents.Credit: Matt Bradbury Based on these insights, Crowley hopes to study whether interventions like attention training could restore appropriate threat processing. Crowley’s team is also working on a test called the Balloon Risk Avoidance Task, which evaluates risk-taking and avoidance behaviors. It features a digital balloon that is full of air and about to burst. Kids have six seconds to let air out of the balloon. The more air they let out, the less risk they face that the balloon will pop. But at the same time, the balloon becomes less valuable as it deflates. “The more air you keep in the balloon, the more points you get,” Crowley explains. So far, the researchers have found that when the balloons pop unexpectedly, teens with social anxiety show distinct brain responses. Studying these responses can help psychologists understand the underlying pathways driving the various manifestations of anxiety. The genetics of anxiety When Thomas Fernandez, MD, associate professor in the Child Study Center and of psychiatry, was still in training, there was a lot of excitement about understanding the genetics associated with autism spectrum disorder. Since then, scientists have identified around 250 genes associated with autism. The genetic contribution to anxiety disorders, on the other hand, has historically received less attention. Anxiety is less heritable than autism, but the genetic contribution for anxiety disorders that emerge in childhood may be higher than for anxiety disorders overall. While scientists estimate the heritability of anxiety disorders in general to be around 30% to 50%, some studies suggest higher heritability for certain childhood-onset anxiety presentations. “I saw firsthand how researchers in the field went about finding vulnerability genes for autism,” Fernandez says. “So, we’re using a very similar playbook for childhood anxiety.” “I saw firsthand how researchers in the field went about finding vulnerability genes for autism. So, we’re using a very similar playbook for childhood anxiety.” Thomas Fernandez, MD Associate Professor In the Child Study Center and in Psychiatry Now, Fernandez and Emily Olfson, MD, PhD, assistant professor in the Child Study Center, are studying children and their parents to identify genetic changes that are present in the child but not the parents, known as “de novo mutations.” “All of us have some de novo mutations—maybe about 50 to 100 sprinkled throughout the genome,” Olfson says. “But when they occur within the coding regions of genes, they can be really disruptive.” Previous research shows that people with autism have higher rates of damaging de novo mutations than the general population. In 2022, Olfson, Lebowitz, Silverman, and Fernandez published a study on 68 children and their families that found that children with anxiety had similarly high levels of these mutations. Studying de novo mutations can help point the researchers to where they should be looking for genes associated with anxiety. “The end game is using the genes to steer us toward the right part of biology that we can then target to come up with better treatments,” Fernandez says. Building on those findings, the team is now studying more families to better understand how these de novo mutations, along with other genetic and environmental factors, shape pediatric anxiety disorders. They recently received a National Institutes of Health grant to enroll 750 new families over the next five years. Olfson is the principal investigator, with co-investigators Lebowitz, Fernandez, Silverman, and Shuangge Steven Ma, PhD, department chair and professor of biostatistics at Yale School of Public Health. Neurodevelopment, Risk Genes, and Mental Health Conditions - The Olfson Lab Joel Gelernter, MD, Foundations Fund Professor of Psychiatry, is interested in how different anxiety disorders differ genomically. “We are studying social phobia, panic disorder, and generalized anxiety disorder, working to understand why people differ in their risk to these specific anxiety disorders and evaluating various risk factors,” he says. Gelernter was recently involved in one of the largest studies to date of the genomics underlying anxiety disorder. The study included around 122,000 people with anxiety disorders and around 730,000 without. It found that some genetic differences associated with anxiety were linked to signaling that helps reduce overactivity in the nervous system. Many anxiety medications available today work by targeting this process. “It’s nice when the biology that you get out of a large genome-wide study ratifies things that we already know because that can help increase confidence in further findings from the study,” Gelernter says. Uncovering the neurobiology of psychiatric disorders John Krystal, MD, Robert L. McNeil, Jr. Professor of Translational Research and chair of the Department of Psychiatry, is interested in the neurobiology of psychiatric disorders, including post-traumatic stress disorder (PTSD), of which anxiety is a major symptom. In the late 1980s, Krystal’s team discovered that the drug yohimbine activated symptoms in patients with PTSD. “This was the first time we could link a specific biological mechanism to the symptoms of PTSD,” Krystal says. At the time, he adds, this finding was highly controversial. “A lot of people felt that PTSD was a purely psychological syndrome that didn’t have an underlying biology.” Since then, Krystal has dived deep into understanding the neurobiology of PTSD to learn how to better treat it. His team is evaluating the use of ketamine and psychedelics. These would be among the first treatments to be developed specifically for PTSD. They may also be applicable for other disorders including anxiety disorders, Krystal adds. An important gap in PTSD treatment is the absence of biological tests that inform how to best help patients manage their PTSD symptoms. A doctor doesn’t diagnose cancer based on how they feel. Rather, they use tests of the biology of the cancer to determine the best course of treatment. “And we can’t do that in any psychiatric disorder other than Alzheimer’s disease,” Krystal says. “But now we are building a foundation for this approach to the treatment of anxiety disorders for the first time.” Source: Yale School of Medicine
Ashes of politics and the preservation of memory
From the perspective of Alija Izetbegovic, genocide is not merely a political crime, but an existential sin committed against the dignity with which God...
Danaher, Nvidia Ink AI-Driven Science Automation Collaboration
The firms will develop iterative automated solutions enabling artificial intelligence-guided scientific research.
Scientists Simulated Microgravity in Human Cells and Found Something Unexpected About DNA
Simulated microgravity changed the nucleus but left the genome surprisingly intact.
What happens when tribal know-how meets climate science? A Cape Cod film
A Cape Cod documentary explores how Indigenous knowledge and science can work together to tackle climate change. 'Climate Voices' will screen Oct. 12.
What happens when tribal know-how meets climate science? A Cape Cod film
A Cape Cod documentary explores how Indigenous knowledge and science can work together to tackle climate change. 'Climate Voices' will screen Oct. 12.
Opinion | Genova: Three political platforms, three visions
American politics includes competing approaches to the economy, energy, immigration, abortion, taxation, transgender rights and the structure of our government. Comparing the published programs of the Democratic Socialists of America (DSA), the Democratic Party and...
Science highlights six landmark DNA and Human Genome Project breakthroughs that missed the Nobel Prize
From Avery’s genetic material discovery to the Human Genome Project’s 3 billion base pairs, major life-science advances faced Nobel limits on co-authorship and timing
M42 CEO on AI, genomics and the future of healthcare
M42 Group CEO Dimitris Moulavasilis discusses how the Abu Dhabi-based healthcare company is combining artificial intelligence, genomics and clinical services to reshape healthcare. He explores the group’s international expansion, the Emirati Genome Programme and the potential for technology to help doctors identify health risks earlier and move healthcare towards prevention rather than treatment.
Where disciplines meet: UTulsa scientists, conservators unlock secrets of centuries-old manuscripts
UTulsa and Gilcrease Museum researchers use Raman microscopy to analyze pigments in 16th-century Indigenous Mexican manuscripts, uncovering historical and scientific insights while preserving cultural heritage.
Jets Captains Hospital Visit (9/15/2026)
Jets captains Geno Smith, Harrison Phillips, Joe Tippmann & Isaiah Williams visited children at the Atlantic Health Goryeb Children's Hospital.
Alamo Museum Brings Karankawa History to Life for Students
Homeschool students received a hands-on lesson in Texas Indigenous history Sept. 22 as Maria del Pilar Garza Museum Director Alejandro Oyoque shared his knowledge of the Karankawa people and guided students in building a bow.
Science Missed the Giraffe’s Only Relative Until 1901
Science ignored the okapi for centuries while Indigenous communities in the Congo knew it well, and even after a skull reached London in 1901, researchers struggled to explain what they were looking a...
Earth's first bats didn't come from where we thought, landmark genetic study reveals
In the largest study of its kind to date, researchers compiled data from 103 bat genomes and 44 fossils to rewrite the bat family tree and determine where these animals first evolved.
Iran Condemns Israeli Atrocities against Palestinians
TEHRAN (Tasnim) – Iran’s Foreign Ministry strongly condemned the Israeli regime’s ongoing crimes against Palestinians, calling for urgent international action to stop the genocide in Gaza and the West Bank.
Verily Health to Integrate PacBio HiFi Sequencing With Data Platform
The multi-year collaboration will link PacBio sequencing workflows to Verily Pre to support biomedical research and AI model training.
'It could have been a very different history': Researchers are finally starting to pin down how many Indigenous people were living in the Americas when Columbus arrived
Archaeologists and geographers have been trying to estimate the pre-1492 population of the Americas for decades. But it's difficult.
Trump Casts Himself as Columbus’s Protector in Pitch to Italian Americans
President Trump sought to inject the Genoese explorer into the current political conversation.
New Study Illuminates Bats’ Murky Origins
The largest analysis of bat genomes and fossils suggests that the first bats emerged in Europe roughly 65 million years ago and that echolocation evolved early.
The American Forest, Maybe Not-So-Primeval
New Yorker explores how Indigenous peoples changed the landscape before colonists
Indigenous tourism awards recognize professionals, artisans and emerging leaders
The American Indigenous Tourism Association honored tourism professionals, entrepreneurs and artisans at its 2026 Excellence in Indigenous Tourism Awards, presented Oct. 21 in Tulalip, Wash. Gary Snow (Mandan, Hidatsa and Arikara Nation), Earth Lodge Village supervisor for MHA Nation Tourism, received the Industry Professional of the Year award. His work includes partnerships with state and […]
Jets' Geno Smith punished by NFL right before Lions game
Just hours before the New York Jets and Detroit Lions game, the NFL announced a punishment for Jets quarterback Geno Smith.
Bats may have first evolved in Europe 65 million years ago
A huge genomic and fossil study suggests bats first evolved in Europe around 65 to 60 million years ago before spreading across the globe. The findings also indicate that flight and echolocation emerged near the beginning of bat evolution, potentially helping explain how bats became one of the most successful mammal groups on Earth.
Geno Smith goes for 252 yards, TD in Week 6
New York Jets quarterback Geno Smith completed 20 of 30 passes for 252 yards, one touchdown and one interception in Week 6
Netflix drops ‘Free Leonard Peltier’ film on Indigenous Peoples Day
The story of one of the most famous prisoners in the United States – Leonard Peltier – is on Netflix, the largest streaming platform, as of Oct. 12.
Geno Smith throws three touchdowns in Week 3
Jets QB Geno Smith posts 321 yards and three TD in Week 3 game
My Word: Gazan performance art
An opening act chanting “Free Palestine” and falsely accusing Israel of genocide sets the stage for more violence.
Trump's 'grand conspiracy' probe presses on with subpoenas after the lead prosecutor’s exit
Justice Department officials are pressing forward with an investigation of President Donald Trump's foes despite the departure of prosecutor Joe diGenova, who had been leading it for months.
The Math Singularity Is Here, and Science May Be Next
OpenAI has released an extraordinary body of mathematical work produced by an unreleased frontier model: 722 manuscripts spanning 372 research families across fields including number theory, complexity theory, and mathematical physics. Each result required, on average, the equivalent of roughly three hours of ChatGPT Pro reasoning. A New Era of Discovery We may be witnessing the beginnings of a “math singularity”: a point at which machine-generated discovery accelerates beyond humanity’s ability to independently reproduce, verify, or fully absorb it. If frontier models can generate hundreds of meaningful results in the time it takes a human researcher to investigate one, the constraint will no longer be producing new mathematics. It will be our capacity to validate, interpret, and integrate it. This does not make mathematicians obsolete. It changes their role. They may increasingly serve as guides, critics, and meaning-makers. Increasingly, they will decide which questions matter, determining which results can be trusted, and explaining why they are important. Mathematical insight may become abundant, while human judgment becomes more valuable than ever. Mathematics May Be Only the Beginning Every scientific discipline could eventually experience a similar acceleration. AI systems could generate and test hypotheses, connect findings across specialized fields, and explore possibilities at a scale no human research community could match. In medicine, imagine models identifying overlooked disease mechanisms, designing drugs and clinical trials, personalizing treatments, or discovering cures in months rather than decades. In materials science, AI could help create better batteries and cleaner industrial processes. In climate science, it could accelerate advances in energy, forecasting, and carbon removal. In biology, it could uncover relationships hidden across enormous genomic and molecular datasets. The result would not simply be faster research. It could expand the frontier of what is scientifically possible. The New Bottleneck Scientific discovery, however, is not the same as scientific progress. A medical breakthrough must still survive laboratory testing, clinical trials, regulatory scrutiny, manufacturing constraints, and real-world deployment. As machine-generated ideas multiply, the bottleneck may shift from producing breakthroughs to validating them safely and translating them into practice. We may soon have more hypotheses than laboratories can test, more drugs than clinical trials can evaluate, and more mathematical results than experts can review. That imbalance will require better systems for automated verification, reproducible research, prioritization, peer review, and collaboration between AI and domain experts. The importance of OpenAI’s work is not merely the number of manuscripts produced. It offers a glimpse of a world in which intelligence can explore thousands of intellectual paths in parallel. If ideas cease to be scarce, humanity’s defining challenge will be deciding which are true, which matter, and how to turn them into progress. The math singularity is not the end of human inquiry. It is the beginning of a new kind—one in which machines expand the frontier of knowledge and humans decide where it should lead. Subscribe Share Leave a comment
Science Missed the Giraffe's Only Relative Until 1901
Science ignored the okapi for centuries while Indigenous communities in the Congo knew it well, and even after a skull reached London in 1901, researchers struggled to explain what they were looking at. Today, this elusive giraffe relative faces threats that make it harder than ever to find, count, or protect.
Venezuelan physician receives PAHO award for advancing Indigenous and intercultural health
Washington, D.C., September 30, 2026 (PAHO) – The Pan American Health Organization (PAHO) today presented the 2026 PAHO Award for Health Services Management and Leadership to Dr. Noly Fernández, recognizing her contributions to advancing Indigenous health care and shaping services that respect Indigenous cultures, knowledge and rights.
Jonathan the Giant Tortoise Is 194 Years Old. He Just Had His Genome Sequenced.
Scientists have sequenced his genome for the first time, hoping the world’s oldest land animal can offer clues into the genetics of longevity.
Heinrich eyes New Mexico jobs in bi-partisan permitting reform push
By Pat Davis, New Mexico Political Report — For most government workers and union members, Columbus Day or Indigenous Peoples’ Day is the Monday cap to a three-day weekend. But that is not true for the U.S. Senate staff and local building trades members working to keep up with Sen. Martin Heinrich’s push to pass […]
Highlighting Mental Health Disparities in Indigenous Communities Affected by Huntington’s Disease
⏱️12 min read | Unique research highlights an overlooked mental health disparity among Indigenous North American people with HD – and the need for care grounded in trust, community partnership, and cultural understanding.
Something Took Wing in Paleocene Sunsets
More than 56 million years ago, something took wing. Now, combining ancient fossils with genomes from living species, researchers are rewriting the bat family tree, and tracing these creatures toward their mysterious beginnings in Paleocene Europe.
Geno Smith finishes with 119 passing yards in Week 4
Jets QB Geno Smith has quiet outing with only eight completions and 119 yards
Drought and state neglect deepen health crisis for Peru’s recently contacted Matsés
A worsening convergence of drought driven by climate change, epidemic disease, and state neglect is creating a severe health emergency for the Indigenous Matsés people in the Peruvian Amazon. Mongabay staff writer Aimee Gabay traveled to Matsés territory to investigate the environmental threats to the region. Instead, she found Matsés communities suffering from severe outbreaks […]
Microbe Discovered With One of The Smallest Genomes on Record, Pushing The Bounds of What It Means to Be Alive
What is an organism, anyway?
DNA from centuries-old skeletons buried in Montreal reveals no genetic mixing between Indigenous people and French colonists
A study of DNA from early colonial-era skeletons in a Montreal cemetery has revealed that none of them had any Indigenous ancestry.
Choctaw Nation Doctor Appointed to Health Tribal Advisory Committee
Overview: The Chief of Staff of Choctaw Nations Health Service has been appointed to a federal tribal health advisory committee. Dr. Amanda Chisum-Price has been appointed to the U.S. Department of Health and Human Services Office of Minority Health Center for Indigenous Innovation and Health Tribal Advisory Committee as an At-Large Delegate. She currently serves […]
Oregon chosen to participate in a research study that screens infants for genetic conditions
Oregon is enrolled in a nationwide newborn genomic screening research study, the Northwest Regional Newborn Blood Spot Screening Program and BRIDGES-NBS program.
German MPs rebuke AfD during genocide debate
The events took place more than 120 years ago, but their consequences are still felt today: Over two days, German lawmakers have been debating their country's colonial crimes in present-day Namibia.
Whether you like it or not, celebrities have an impact on politics
The global groundswell of support for Macklemore’s pro-Palestinian advocacy serves to remind us that maybe celebrity activism really is that deep after all, writes Cheek’s Varsha Yajman. Subscribe In the last week, publications, podcasts, and influencers that have either rarely or never spoken about Israel’s genocide in Palestine have flooded my social feed. And it was all because singer Ed Sheeran and his team dropped Macklemore as his opener for saying “Free Palestine” on stage. Millions raised, millions speaking up in support of Palestine - all of this confirming my view that, whether I like it or not, celebrities do have an impact on political outcomes. And this is interesting when much of the time celebrity activism can induce an eye roll - I love to see Charli XCX pointing out a Palestinian flag in the crowd, but it’s hardly the bold symbol of allyship that some fans would make it out to be. But there’s a line between healthy scepticism and outright dismissal - and I’d argue that the latter lets the rich and powerful off far too easily. For instance, actress Jennifer Lawrence, once outspoken about her political views, last year told The Times she no longer believes celebrities have a role to play: “Celebrities do not make a difference whatsoever on who people vote for. So then what am I doing? I’m just sharing my opinion on something that’s going to add fuel to a fire that’s ripping the country apart.” While it’s a narrative she might find comfort in, it simply is not true. Grassroots movements often garner worldwide attention when celebrities and other high-profile spokespeople bring a mainstream platform to their causes. And this frustrates me. We have had three years of a live-streamed genocide. Macklemore himself has been calling for a Free Palestine long before he booked the Sheeran concert. Yet it’s the high-profile fallout of the last week that finally seems to have made saying “Free Palestine” socially acceptable in the mainstream. It feels like the collective mood has shifted, where calling out censorship is now the obvious response - not just the business of ‘radical’ activists. To recap, Sheeran’s decision followed an ultimatum from billionaire Robert Kraft, owner of Gillette Stadium, one of the venues Sheeran was scheduled to perform at: either drop Macklemore as your opener after only two of the eight scheduled shows, or you do not play at any stadiums. Sheeran’s disappointing decision to stand on the side of billionaire-led censorship has ultimately seen a surge in support for Free Palestine. It began when all his openers and his backing band pulled out of Sheeran’s tour, in solidarity with Macklemore and with the Palestinian cause. It was met with an uproar of support from those who had never or barely touched politics before: influencers lip-syncing to Macklemore’s music, singers like Jack Antonoff singing “Free Palestine,” and publications and podcasts standing with Macklemore. And finally, we saw material support: Macklemore donated $1 million in profits from his two nights opening for Sheeran’s tour to several Palestinian aid groups and called for Sheeran and Kraft to match it, which they have since promised to do. We’ve also seen children’s entertainer Ms Rachel follow suit with a $1 million donation to Palestinian aid, and publication PopBase has donated $10,000. Anera, a humanitarian aid group working in Palestine, Lebanon, and Jordan, said donations since Macklemore’s announcement were more than triple this month’s daily average. The group’s Instagram page has also gained 8,000 followers. Macklemore far from the first celebrity to speak and participate in politics in the Western World. In 1924, singer Al Jolson supported Republican candidate Warren G. Harding for president, and decades later, celebrities such as Harry Belafonte, Lena Horne, and Aretha Franklin voiced their public support for the Civil Rights movement. More recently, in the lead-up to the 2024 US election, ‘The Daily Show with Trevor Noah partnered with the organisation Power the Polls to recruit poll workers to address shortages- a problem disproportionately affecting voters of colour. The campaign saw 170,000 new sign-ups - 35,000 of which came directly through the TV show’s link - resulting in the recruitment of 713,000 total poll workers that year, an almost three-fold increase on the organisation’s goal. Alongside recruiting workers, celebrities in the US (where voting in elections is not compulsory) have made a huge difference by calling for people to register to vote. Taylor Swift’s endorsement of Kamala Harris in 2024 saw over 400,000 visitors on the voter registration site within 24 hours of her Instagram post. In 2023, Swift had urged her fans to register, resulting in 35,000 new voter registrations. Similarly, Ariana Grande promoted voter registration in 2019 by setting up booths at concerts on the American leg of her tour, resulting in over 33,000 voters registering. And the same thing is happening closer to home. This year, musician Jack River successfully called for government action to ensure creatives in Australia do not have their work scraped by generative AI companies. Celebrity as the mediator between the punter and the politician Celebrity activism isn’t just a feel-good news story - research tells us it actually makes a difference. By directing attention to issues affecting the average person, like voting inaccessibility or a lack of action on a genocide, researchers Alfred Archer and Amanda Cawston state that “celebrities can play a useful bridging role between political elites and the people they represent”. Alternatively, in a world where talking about politics is “not cool,” or where people lack exposure or knowledge to engage with politics, celebrities can act as an educational resource or an entry point into the political world - when they speak up about an issue, their audience gets exposed to it. Olivia Rodrigo’s Daisy Chain Fields festival is a perfect example. Rodrigo partnered with twelve organisations focused on women’s issues, such as reproductive rights. These organisations had stalls at the festival for people to meet them and were also featured heavily on social media, giving their issues global attention and raising $20 million for the organisations. We have also seen celebrities at award shows such as the Emmys wearing F*CK ICE pins, referring to the U.S. Immigration and Customs Enforcement’s treatment and detainment of people - generally people of colour. When celebrities speak up about political issues in public forums, they put the issue at the forefront of mainstream media, rally their supporters, and make it clear that, however much they disagree, the government cannot simply ignore it. Our over-reliance on celebrities versus our politicians As much as I love seeing my favourite celebrity use their platform for a good cause, there is an important question to ask: not whether celebrity activism is good or bad, but whether we should have to rely on celebrities. And the answer would, in an ideal world, be no. In an ideal world, or merely a just world, action on Palestine would’ve happened decades ago, climate change would be taken seriously, and most importantly, people would understand their democratic rights. However, that is not our reality. Only around 28 per cent of Australian Year 10 students reach proficiency in civics and citizenship. In the US, almost two-thirds of people under 30 say high school civics education didn’t prepare them to understand voting deadlines, how to research candidates, or how to vote by mail. When civics education is weak, our trust in these institutions and our understanding of change-making processes also decline. This is where celebrity steps in and becomes our main source of reliance. As Mary R. Connelly notes in _The Tartan, “_Celebrities will always be involved in campaigns in one form or another, but their presence is not what causes people to vote blindly. The lack of political engagement and literacy is what allows celebrities to wield their influence on the political sphere so impactfully.” About the author Varsha Yajman is the Digital Content Producer at Cheek Media. She is a youth advocate and lawyer with a background in climate litigation and is passionate about looking at the intersection between race, climate justice, and mental health. Thanks for reading Cheek Media Co. ! This post is public so feel free to share it. Share