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Budget 2026: What might the Chancellor do on business rates?
Rating experts at Colliers anticipate five significant changes
Chancellor plans to end pointless paperwork to cut £800m business costs
Ministers say the changes in regulations will reduce unnecessary bureaucracy.
AACI to Recognize Excellence in Cancer Research, Health Equity, and Philanthropy at Annual Meeting
The Association of American Cancer Institutes (AACI) will recognize excellence in cancer research, health equity, and philanthropy during the 2026 AACI/CCAF Annual Meeting in Chicago. The awards ceremony will begin at 10:45 am central time on Monday, October 26.
Gears of War: E-Day, Cancelled Last-Minute for PS5, May Have Cost Half a Billion to Make
Fenix down
Lost to Science for 89 Years, a Venomous Primate Has Been Sneaking Into People’s Homes and Gardens
Scientists working with Indonesia’s Alobi Wildlife Rescue Center have confirmed that the critically endangered Bangka slow loris—while excellent at hiding—is very much not extinct yet.
The Crooks family business is volleyball excellence
Wesleyan Christian Academy's Nejari Crooks is heralded as a 5-star volleyball prospect committed to Penn State. Her coaches at WCA are her own parents, each of which have their own storied history with the game of volleyball.
Toronto Blue Jays Closer Honored with Award Selection
Louis Varland had an excellent 2026 season that continues to earn him recognition.
Judge directs President Trump to sit for deposition in his $10 billion lawsuit against the BBC
Trump had agreed to sit for a deposition on Oct. 16, but it was cancelled for what was described as a “matter of national importance.”
Indigenous tourism awards recognize professionals, artisans and emerging leaders
The American Indigenous Tourism Association honored tourism professionals, entrepreneurs and artisans at its 2026 Excellence in Indigenous Tourism Awards, presented Oct. 21 in Tulalip, Wash. Gary Snow (Mandan, Hidatsa and Arikara Nation), Earth Lodge Village supervisor for MHA Nation Tourism, received the Industry Professional of the Year award. His work includes partnerships with state and […]
‘There’s no way to stop them’: How campaigns and PACs get away with nonstop texting
Both parties purchase data to build a voter file with info like cell phone numbers. That means there's almost no way to stop the texts.
A revolutionary new microscope could reveal the hidden machinery of life
Researchers have developed a revolutionary microscope that uses an incredibly powerful laser to make previously invisible cellular structures easier to see. The technology dramatically improves image clarity, allowing scientists to examine small proteins that conventional electron microscopes struggle to capture. It could eventually reveal how tiny molecular machines interact inside cells, providing an unprecedented look at the hidden workings of life.
Radiologist FDA leader believes generative AI should be evaluated like human docs
Rick Abramson, MD, director of the FDA’s Digital Health Center of Excellence, recently spoke during a panel held in Boston by industry lobbying group AdvaMed.
Chancellor to pitch budget at wealth creators
John Healey is expected to cut red tape requirements, particularly for smaller businesses
Mexican Mafia member found dead in California state prison cell
Richard Buchanan, a reputed Mexican Mafia from the San Diego area, died in prison Tuesday morning, authorities said. Guards found Buchanan unresponsive in his cell at Kern Valley State Prison,
Scientists discover a surprising secret behind the human brain’s wrinkles
Scientists have discovered why common marmosets have unusually small, smooth brains despite starting development much like other primates. The secret lies in subtle changes to brain-building cells that slow neuron production, revealing new clues about how the large, folded human brain evolved.
1970 Chevy Camaro For Sale With 90,000 Miles Shown Packs Supercharged V8 And 5-Speed Stick
Highly modified but in excellent condition, this supercharged 1970 Camaro is being offered for sale at a price that rivals the new Mustang Dark Horse.
School cellphone ban clears Pa. Senate, awaits Gov. Shapiro’s signature
Pennsylvania is one step closer to banning cell phones in public schools across the state after the Senate voted Wednesday to approve a measure sent over by the House on
CentraCare healthcare system to acquire Stellis Health in merger of central Minnesota providers
The two organizations already have a history of collaboration, including at CentraCare-Monticello hospital, where Stellis physicians provide care. The move comes as Minnesota’s healthcare systems face increasing financial pressures.
After 75 years serving Monticello and Buffalo, Stellis Health plans to join CentraCare
Stellis Health says its commitment to the communities it serves "isn't changing" as it plans to become part of CentraCare. Shareholders have voted to move forward.
Review: Final Fantasy Resonance: Impressive 2D-HD Visuals, Excellent Performance on Every Platform
But what's up with image quality on Xbox Series S?
Take a break from opinion-page politics next week
Sometimes I think I’d take tornado season over election season. And that strikes me as an apt comparison as I imagine sheltering beneath a hinged cellar door until the storm has blown over — physically in one sense, mentally in the other. As an example of the debris flying around this season, my inbox was
2026 Honored Alumni Lecture: Science and Faith are Friends, Not Foes
Cellular biologist Jeff Stogsdill returned to BYU as the 2026 Life Sciences Honored Alumni and gave a lecture sharing how faith and science don't compete; they complement each other.
How Lucille Ball Saved ‘Star Trek’ to Become a Six-Decade Juggernaut Franchise
Roddenberry Entertainment COO Trevor Roth on Wednesday told the MIA Market in Rome how the comedy legend and her Desilu Productions put the quirky sci-fi series into reruns after an NBC cancellation.
Too much RNA can starve cells of energy, scientists discover
Scientists have uncovered an unexpected danger lurking inside cells: too much RNA can damage the structures responsible for producing energy. A new study found that excess RNA, including the normally essential messenger RNA (mRNA), can directly disrupt mitochondria without relying on the immune system. The discovery could help explain how viral infections and certain aging-related diseases damage cells.
Celebrating Scholars for Mental Health
SUNY Chancellor John B. King Jr. today celebrated five Scholars for Mental Health who have demonstrated leadership and a steadfast commitment to bolstering the mental health field. Through funding...
The humble one-celled alga that helped scientists win the Nobel prize
Chlamydomonas and its light-sensing protein help show how memories, feelings and behaviour form in our brains
Apple is looking for a cellular modem engineer as it eyes 6G
Apple is looking for an experienced cellular modem systems engineer to help develop its next generation of cellular modems as the company transitions toward 6G.
Businesses Report Flat Summer Tourism Despite Inflation, Smoke and Airport Runway Closure
In August, when an active wildfire season in the Pacific Northwest choked the Flathead Valley in a dome of smoke, Glacier Guides and Montana Raft owner Denny Gignoux started getting cancellation requests and noticed lower demand for rafting and hiking trips at his outfitting business. While the smoky skies deterred some visitors from traveling altogether, […]
‘Healthy Rounds’: Supercharging the Immune System
Dr. Kapil Meleveedu, director of UConn Health’s Blood and Marrow Transplant and Cellular Therapy Program, joins Dr. Anthony Alessi’s podcast
MSU celebrates 25 Years of Imaging Sciences excellence
Morehead State University marks 25 years of undergraduate imaging sciences education, celebrating student success, faculty support and healthcare impact.
Abbott, Big 10 Conference, Rutgers Athletics, and RWJBarnabas Health Seek to Boost National Blood Supplies
Diego Orozco knows firsthand that every blood donation offers new hope for blood cancer patients like him. After battling leukemia and enduring three stem cell transplants, the 34-year-old North Plainfield resident has relied on countless blood transfusions to survive some of the most difficult moments of his cancer journey.
Scientists finally uncover why statins can cause muscle pain
Scientists have uncovered a surprising reason why statins, the widely prescribed cholesterol-lowering drugs that help prevent heart attacks and strokes, can sometimes cause muscle pain, weakness, and even severe muscle damage. Using advanced imaging technology, researchers discovered that statins can attach to a crucial protein in muscle cells and force open a channel that normally controls calcium flow. This causes calcium to leak continuously, potentially damaging muscle tissue.
Names in the News: People shaping the future of Lake Area business
Sowela appoints vice chancellors Sowela Technical Community College is pleased to announce the promotion of two distinguished members of its leadership team, Allison Dering and Dr. David LaFargue, from executive […]
Pfizer makes ‘business decision’ to end phase 2 trial of autoimmune drug as program’s future uncertain
Pfizer has called time on a phase 2 trial of its CXCR5 antibody in an autoimmune blood disorder, with the company tight-lipped on whether this marks the end of the road for the asset. The Big Pharma had been evaluating the therapy, dubbed PF-06835375, in a phase 2 study of 61 patients with primary immune thrombocytopenia (ITP) that kicked off in 2022, according to the federal trials register. However, Pfizer confirmed to Fierce on Monday that this study had been terminated “due to a business decision.” “The decision to terminate the trial was not based on any safety concerns,” a spokesperson pointed out. At time of publication, PF-06835375 remained listed on Pfizer’s website for both ITP and lupus. A phase 1 study in lupus wrapped up in 2022, according to the trials database. ITP is an autoimmune disorder characterized by a low platelet count. Novartis was at one point evaluating its B-cell-depleting antibody ianalumab—recently approved as Fabhalta to treat immunoglobulin A nephropathy—as a potential treatment ITP. But the therapy struggled to demonstrate a benefit in the clinic for this indication. When contacted by Fierce, Pfizer wouldn’t confirm whether all work on PF-06835375 has been halted, and whether the company has any other plans to explore C-X-C chemokine receptor type 5 (CXCR5) as a mechanism. CXCR5 is found in blood cancers such as diffuse large B-cell lymphoma and mantle cell lymphoma chemokine receptor. However, there is little expression in normal tissue, which has led some drug developers to explore its potential. Vincerx Pharma had at one point been planning to take an anti-CXCR5 ADC into the clinic to treat B-cell malignancies, but that ambition was scrapped due to cash constraints. Where Big Pharma is placing its bets is one of the hot topics being discussed at Fierce Biotech's high-impact event in London next month. Find out more information and register by clicking on the banner below: [ ](https://qtxasset.com/quartz/qcloud5/media/image/where_big_pharma_is_placing_its_bets.png?VersionId=B8JrRbJ.pFUSK1pJgjeWHLGm_18RdLAy)
SMARTIES Asia Pacific 2026 Finalists Announced: Showcasing Peak Marketing Excellence and Business Impact
/PRNewswire/ -- Marketing + Media Alliance (MMA) announces the SMARTIES Asia Pacific 2026 Finalists, recognizing campaigns that demonstrate exceptional...
5 Cheaper OLED TVs To Buy Instead Of The Samsung S95H
While the Samsung S95H is an excellent OLED TV, it can get pricey, depending on the size you pick. Here are some affordable alternatives from other brands.
‘Open your doors for AI’: German chancellor urges businesses to embrace AI as Nvidia announces new investments
Nvidia announced planned investments in four German startups as Chancellor Friedrich Merz urged businesses to embrace AI at an industry summit in Berlin.
Scientists discover a surprising link between vitamin C and cancer survival
A surprising clinical trial suggests that taking vitamin C daily could improve survival in people with precancerous blood disorders and early-stage blood cancers. Patients receiving the supplement had fewer adverse events and showed a promising survival advantage, raising hopes that a common vitamin could help protect against leukemia-related complications.
“Cellar Door” ending explained: What’s really behind the cellar door?
Laurence Fishburne makes a married couple an offer they should’ve refused in the 2024 horror thriller.
RWJBarnabas Health Honored with New Jersey Business Magazine’s Community Service Award
RWJBarnabas Health has been recognized with New Jersey Business Magazine’s 2026 Community Service Award for Excellence for its Our Healthy Communities initiative, which addresses health disparities and strengthens communities across New Jersey through expanded access to health care, healthy food, housing, and economic opportunities.
RWJBarnabas Health Honored with New Jersey Business Magazine’s Community Service Award
RWJBarnabas Health has been recognized with New Jersey Business Magazine’s 2026 Community Service Award for Excellence for its Our Healthy Communities initiative, which addresses health disparities and strengthens communities across New Jersey through expanded access to health care, healthy food, housing, and economic opportunities.
Best of Business
TCB Event Best of Business Description Each year, TCB asks the business community to cast their votes for the top companies to do business with in Minnesota. This event will bring together companies that exemplify true excellence for a celebration and reveal the rankings of the Gold, Silver, and Bronze winners in a wide range of categories.
Local Malheur County educators honored with top Oregon Science Teacher Association awards
Five educators from Malheur County were recognized for excellence in science and STEM education by the Oregon Science Teachers Association at its annual conference in Pendleton.
What Does a Human Heart Need to Grow? Scientists Found the Answer in a Bioprinted Model
Heart problems that babies are born with, called congenital heart defects, often begin developing early in pregnancy. Approximately three weeks after fertilization, the human heart is still a simple, straight tube of cells and, over the course of about five weeks, this tiny structure must undergo a remarkable transformation to reshape itself into the complex organ that eventually pumps blood throughout the body.
A gene variant triples the risk of getting Alzheimer's disease — fat buildup in brain cells may be to blame, study finds
A gene variant called APOE4 is the biggest genetic risk factor for Alzheimer's disease. Scientists are finally figuring out how it works.
AI Cloning Threatens To End Public Playtests For Video Games
Moonlighter dev Digital Sun has cancelled plans for a public playtest of its next game, for fears of Claude clones
EasyTone Lab Introduces Science-Led Supplement Lineup for Everyday Wellness
EasyTone Lab launches science-led EGT, NMN and White Tomato supplements for cellular wellness, daily energy and skin radiance, made in the U.S....
The immortal jellyfish can beat ageing and death. Its genetics could help human cells rejuvenate
The immortal jellyfish is capable of winding back its lifecycle to become young again. Scientists are unlocking its cellular secrets for new strategies to treat diseases of old age.
Nvidia CEO among top business execs to attend German investment summit
Germany is set to host top business executives, including Nvidia boss Jensen Huang, on Monday for a summit that Chancellor Friedrich Merz hopes will help to attract private investment to boost the sluggish economy. Europe's largest economy has struggled to attract foreign investment amid years of weak growth, with high energy prices and labour costs continuing to deter businesses.
Bragg receives DAISY Award for nursing excellence at Vandalia Health Broaddus Hospital
Criss Bragg, a charge nurse at Mansfield Place, received Broaddus Hospital’s DAISY Award after a colleague nominated him for compassionate care and support of fellow staff.
Three Ballad Health hospitals recognized nationally for excellence in stroke care
Bristol Regional Medical Center, Holston Valley Medical Center and Johnson City Medical Center earned awards from the American Heart Association for stroke care.
Streaming’s Biggest Show Returns…and a Buzzy Genre Struggles
(Welcome to my weekly streaming ratings report, the single best guide to what’s popular in streaming TV and what isn’t. I’m the Entertainment Strategy Guy, a former streaming executive who now analyzes business strategy in the entertainment industry. If you were forwarded this email, please subscribe to get these insights each week.) Obviously, the big news of the week (if not month) is Netflix letting go of executive Bela Bajaria, their chief content officer. I’m going to cover this in my next “Most Important Story of the Week”, but I also have a data angle that I might publish before then. (Too much news this month, am I right?) But first, I have a bonus Streaming Ratings Report issue for you. Today’s article is a bit of a grab bag of topics I’ve wanted to write about, but couldn’t squeeze into the (already very long) Streaming Ratings Report issues. The NFL drives huge viewership numbers, so I’ve got a look at that. A whole bunch of TV shows returned to the traditional broadcast channels, and I have thoughts. And I have a quick look at adult animated shows, since a couple flopped earlier this month. Plus, the Emmys aired earlier this month, and we got some fun data bout how popular those nominated shows are and why I’m not optimistic about the show’s future. That’s a lot, so let’s dive right in. Subscribe Sports - Football Remains the King of Streaming Over the last two Streaming Ratings Reports, I sorta ignored the biggest “show” each week. (I was tempted to say “piece of content” but I know that word bugs folks.) In my database, I call these “specials”, and they sure are special. I speak of the king of American TV: football!!! Streaming football is back and, unlike some other sports, it routinely dominates all viewership. Probably the best way to show this is to update one of my favorite graphics, the “40 Million Hour Club”1 since football games have joined that club each week they’ve premiered: (Yep, that’s the data through 28-Sep, the first four weeks of the season. As a reminder, I take the average minute audience provided by Nielsen, factor out a percentage of linear TV viewers in home markets, and multiply the run time by the three-hour runtime.) Again, the numbers are huge. Let’s start with Netflix. They grabbed the rights to the bonus opening week NFL Kickoff game (which was on YouTube last year) and it put up 18.5 million viewers on average. That nets out to 47.4 million hours of estimated streaming hours. That’s good! Though, notably, it’s well below Christmas Day games from previous years. Compared to other streamers/broadcasters, that’s a bit of a mixed result. On one hand, Netflix’s 18.5 million average is about what YouTube claimed last year, though Nielsen used a bespoke methodology at that time, so I trust this viewership figure more. So that’s good. (The game also shifted from a Friday to a Thursday and that could have helped the viewership as well.) And Netflix continues to best Prime Video in total viewership—as you’ll see next—though Netflix has had much higher-profile (opening week and Christmas Day) games. NBC/Peacock’s opening game the night before averaged 25.1 million average viewers, which is just much bigger than Netflix (or Prime Video). That’s the big caveat to all streaming viewership records: even in success, they can’t compete with traditional linear TV. Previously, I called this my “hierarchy of viewership”, and the data keeps supporting that thesis. The downside for NBC is that this game’s viewership was down compared to previous years, though it may be a counting issue. Here’s a great chart from Sports Media Watch: Indeed, looking at all the opening week games across all windows, Netflix still lags the other primetime windows, but does well compared to the afternoon games: I saw a few folks make the case that streamers still lag traditional broadcasters in reach, and I’d add they really lag compared to “broadcast plus streaming” options like NBC/Peacock, ESPN/Disney+ and CBS/Paramount+. The best data I saw for this came from Samba TV, who charted reach through the 2025 season, and, wow. (Samba TV’s numbers are historically lower than Nielsen’s, so don’t compare their household figures to Nielsen’s hours, but use them as a proxy for the relative reach of the streamers.) The good news is Prime Video is NOT having a down year. Their opening Thursday Night Football game reached 18.6 million viewers (about what Netflix got), but that’s a high for Prime Video on Thursdays and the biggest Thursday night game since 2015. The TNF games the weeks of 21-Sep and 28-Sep continued this streak, getting 43.1 (16.8 million average viewers) and 42.5 total hours (16.6 million average viewers), which were both up from last year. Still, that continues the (typical) season slide: (For those new-to-streaming-football-numbers folks, the viewership declines for Thursday Night Football as the year goes along.) Overall, it appears as if Prime Video is now part of the “football habit”, be it for customers at home or out at places like bars and restaurants. And its viewership is slowly catching up to broadcast. One last chart shows this. Last season, Nielsen started adding out-of-home viewership to the charts, so I try not to do season-to-season comparisons as I did for the first few years. And while Nielsen added Big Data viewing this year, I’m going to compare the last two seasons. Here’s that chart, which shows the season-over-season gains: When it comes to streaming football, we have to keep a few seemingly contradictory thoughts in our head… First, streaming doesn’t come close to matching broadcast’s reach and, thus, viewership. Second, even with that gap, football is still the biggest “thing” on streaming. It’s very, very popular. Third, while some methodology changes have likely helped Prime Video’s numbers, their viewership does appear to be growing. Lastly, yeah, the NFL started the season off poorly, with week one dragging down the numbers in year-over-year comparisons. However—and again, methodology changes may have helped this—the viewership grew compared to previous seasons over the next couple of weeks. So football is still king. On streaming and off. Television - Adult Animation Continues to NOT Make the Streaming Charts In the last two reports, two adult-animated shows whiffed: Netflix’s animated comedy, Dang! Paramount+’s Sega-video-game-inspired fantasy/comedy, Golden Axe. Neither made the charts, but that’s usually the case for animated shows. I mean, here’s literally every animated show that’s made the Nielsen Original charts since the start of 2025: And one of those shows is G_abby’s Dollhouse_! A kids show! The problem with charts like this is that they don’t give you a sense of how many shows miss the charts. Netflix had at least eleven animated flops, including comedies like Big Mouth (a show everyone assumed was popular in the pre-Streaming Ratings Era), Long Story Short, Haunted Hotel, Mating Season, Strip Law, and Alley Cats, and action shows like Blood of Zeus, Castlevania: Nocturne, Devil May Cry, Splinter Cell: Deathwatch, and Tomb Raider: The Legend of Lara Croft. Prime Video had at least six animated misses, two in the same universe (Hazbin Hotel, Helluva Boss), three more comedies (#1 Happy Family USA, The Second Best Hospital in the Galaxy and Kevin) and an action show (The Mighty Nein). Disney+ had MCU and Star Wars animated misses (Eyes of Wakanda, Marvel Zombies, Star Wars: Visions, Star Wars: Maul – Shadow Lord, and Star Wars: Tales of the Underworld) but I can’t tell how many of those shows were geared towards adults. HBO Max had Harley Quinn and Hulu had Solar Opposites. None of these shows made the charts! That’s a lot of misses! If I remade the chart with all those misses, here’s how it would look: Listen, I know the counter arguments. First, it’s cheaper to produce animated shows than live action. Fair enough, but with viewership this low, even that cheaper price point starts to not matter. Second, just look at the acquired charts. Hit animated comedies can generate viewership for years! Shows like The Simpsons, South Park, Family Guy, and Bob’s Burgers do really, really well. Fair enough, but streaming has failed to recreate the dynamic that Fox has mastered so well. That’s a problem for streaming still. Television - Emmys! The annual Emmys broadcast was a few weeks ago, and I’ve got data on how the nominees performed on streaming, plus hot takes on this year’s viewership (and the big news about the broadcast’s, er, streamcast’s future). We’re just getting started with this issue, but the rest is for paid subscribers of the Entertainment Strategy Guy, so if you’d like to find out… The top Emmy-nominated shows… ...why I’m worried about the future of the Emmys telecast... ...the pros of broadcast television ...and the cons... ...please subscribe! We can only keep doing this great work with your support. Coming Soon! Next week, we’ve got a double issue (since the weeks of 21-Sep and 28-Sep were so light), but then I’ll be all caught up after a deluge of streaming ratings data from Nielsen in September. In the meantime, I’m going to try to take a look at Netflix’s stats to explain why Bela Bajaria is out. But even light weeks give me plenty to talk about. The Great British Baking Show returns to Netflix and Apple TV has a buzzy new star-studded comedy. And Netflix has a controversial-but-appears-to-be-popular new game show. Plus big films like Toy Story 5, Backrooms and The Breadwinner head to streaming. And is East of Eden a hit? After that, The Kardashians return to Hulu, Prime Video has a reboot of Carrie, and Netflix has a horror show, Below. Disclosure Day heads to Peacock, The Housemaid heads to HBO Max_,_ a new Ben Affleck film, Animals, lands on Netflix, and Apple TV has a new John Cena action film based on, checks notes, Hasbro’s Matchbox toys. Okay. Longterm, some interesting TV production news. HBO Max ordered How to Survive Without Me, starring Kaley Cuoco, Joshua Jackson, Ray Romano and Rita Wilson, for fifteen episodes! I love that some streamers (or, at least, HBO Max) are finally ordering TV shows with more than eight episodes. In less wise production news, Landman does not appear to be coming back this year, since it just started production. Frankly, I don’t love this (get your shows out on time) but Landman is so popular, I doubt it matters.
South Texas Health System (@stxhealthsystem)
2 likes, 1 comments - stxhealthsystem on October 18, 2026: "Put Your Skills at the Heart of Innovation: South Texas Health System is seeking skilled and dedicated Cardiac Cath Lab Technologists to join the cardiovascular teams at STHS Heart and STHS Edinburg. In this vital role, you’ll support advanced cardiac procedures, help deliver potentially lifesaving care and make a meaningful difference for patients when it matters most. Join a team committed to clinical excellence, innovation and compassionate care. Ready to take your career to the next level? Explore opportunities with the Rio Grande Valley’s largest integrated healthcare network. STHS offers competitive pay, comprehensive benefits and an increased sign-on bonus for qualified applicants. Ready to make your next career move? View current openings and apply at the link in our bio.".
Apple Reveals iPhone Duo's Battery Capacity
Apple on Friday published an EU energy label for the iPhone Duo that reveals the device has a total battery capacity of 4,883 mAh. The document appears to confirm a previous leak that showed the iPhone Duo has 2,962 mAh and 1,921 mAh battery cells totaling 4,883 mAh. iPhone Duo is an eSIM-only device, so this battery capacity figure should apply worldwide, as there is no version of the device with a physical SIM card tray that would have a slightly smaller battery.
Woman allegedly hit business owner with a closed fist when he tried to stop robbery
KOKH Fox 25 provides, news, sports, weather and local event coverage in Oklahoma City and surrounding areas, including McLoud, Shawnee, Tecumseh, Seminole, Wewoka, Maud, Asher, Wanetted, Goldsby, Norman, Blanchard, Chickasha, Pauls Valley, Purcell, Andarko, Bridgeport, Lawton, Duncan, Okarche, Kingfisher, Guthrie Stillwater and Cushing, Oklahoma.
Woman allegedly hit business owner with a closed fist when he tried to stop robbery
WGXA News Fox 24 and ABC 16 in Macon Georgia provides local and national news, weather, sports and notice of community events in surrounding towns, including Warner Robins, Gray, Forsyth, Musella, Roberta, Milledgeville, Phoenix, Monticello, Hawkinsville and Montezuma, Georgia.
Brown Fat Can Be Beneficial For The Body – And a Blood Pressure Drug Could Turn It On
Physical and mental health boosts.
Leukemia That Refuses to Choose: The Science of Mixed Phenotype Acute Leukemia
A new review in Cancer Cell International synthesizes contemporary classification, clonal biology, and precision therapy for mixed phenotype acute leukemia, arguing that management must track the founding clone across phenotypic states rather than rely on static lineage labels.
Qian Jiang, former Johns Hopkins’ eye institute expert, joins Chinese hospital
Chinese specialist leaves US for Sir Run Run Shaw Hospital to research eye transplants and work on virtual cells to test drug responses.
Best Hulu deals and bundles: Best streaming deals in October 2026
Stream excellent shows and movies at a heavily discounted price.
Islanders 4 (EN), Maple Leafs 1: Costly but gritty win
The Islanders pulled off an impressive 4-1 win in Toronto despite losing two forwards for most of the game, with both Cal Ritchie and Matias Maccelli limping off to destinations unknown in the first period. Ritchie was the first to leave, on his first shift, but he was at least able to skate off after […]
Scientists discover that male and female skin play by different rules
Scientists have uncovered a surprising difference in how male and female skin repairs and renews itself. By tracking individual skin stem cells in living mice for five months, researchers discovered that female cells work together in a highly coordinated way, while male cells operate more independently. This synchronization, driven by sex hormones, helps explain why wounds heal faster in female mice, especially during the first few days.
Excellus earns four-star rating for commercial health plans
UTICA — Excellus BlueCross BlueShield has earned a four-star rating from the National Committee for Quality Assurance for its commercial health plans, the insurer announced Oct. 5.
2026 Nobel Prize in Medicine Honors Breakthrough That Lets Scientists Control the Brain With Light
An algal protein helped scientists reactivate a fear memory in mice, turning light into a tool for testing what specific brain cells do. Scientists who worked out how to control brain cells with light have won this year’s Nobel Prize in Physiology or Medicine. Karl Deisseroth, Peter Hegemann, and Georg Nagel were honored for their
Appeals court blocks part of Arizona prison healthcare order
The 9th Circuit Court of Appeals, in the unsigned order, said that the state is raising "serious questions" about the ability of a federal judge to take over health care in a prison system.
Scientists Found a Way to Upgrade the Powerhouses of Our Cells Without Shutting Them Down
Scientists have developed a new way to coat mitochondria, the tiny structures that power our cells, while preserving much of their function. Researchers at two Italian institutions found that coated m...
Brain cells meant to protect us may be fueling cognitive decline
Scientists have uncovered a surprising cause of age-related cognitive decline involving brain cells previously thought to be entirely beneficial. As these cells become dysfunctional, they can produce abnormal amounts of myelin, disrupting nerve fibers and potentially contributing to worsening memory and thinking skills.
Scientists discover cell division does more than make new cells: It helps reshape tissues
Every time a tissue grows or renews itself, cells must divide inside an already crowded environment. That creates a fundamental problem that scientists have not fully understood: How does a tightly packed ...
Scientists turn cancer-promoting protein into a weapon against tumors
Researchers have discovered that a protein known to help cancer cells thrive can also make immune cells more effective at destroying tumors.
Board of Regents: Candidates talk issues ahead of Nov. 3 election
Name: Edie Hooton Office Sought: Colorado Board of Regents, District2 Party: Democrat How should the Board navigate curriculum debates that have become politically polarized? Curriculum decisions must be anchored in the principle of “shared governance,” as defined in Regent Laws. The responsibility for academic excellence lies with the faculty and subject matter experts, as they […]
We have reached a new threshold in genAI gloom, with a game dev cancelling a demo for fear of copycats ripping them off before release
The creators of Drunken Goddess Reflux have cancelled a demo for fear of genAI copycats making a clone before they release the game.
Scientists Kept Finding The Same Mysterious DNA In Their Samples. The Marine Microbe It Belongs To Has The Smallest Genome Ever Identified
This tiny marine organism may demonstrate just how little genetic material a cell needs to survive.
Princeton Engineering - Endowed professorships recognize excellence in computer science
Three computer scientists at Princeton Engineering have been named to endowed professorships.
Technics EAH-A1000 review: Superior sound and excellent ANC in a premium package
Technics’ flagship over-ear wireless headphones are light on compromises, but enter a competitive market.
USC scientists discover how to create a never-ending supply of cancer-fighting cells
USC scientists have discovered a way to create a potentially renewable supply of genetically engineered immune cells that can attack cancer and strengthen the body's natural defenses. By growing and modifying immature immune cells rather than mature ones, researchers developed a system that can continuously produce tumor-fighting cells inside the body.
Footage from a reportedly cancelled Assassin’s Creed game set in China has leaked
The title known as ‘Assassin’s Creed Destiny’ was allegedly cancelled by Ubisoft…
Pioneering heart stem cell expert Li Renke dies at a Chinese meeting aged 65
A memorial service will be held for the Chinese cardiovascular scientist who used engineering principles to treat heart conditions.
UCLA Health addresses healthcare accessibility issues for Spanish speakers
Three UCLA Health initiatives are working to make healthcare more accessible for Spanish speakers across Los Angeles. The UCLA Hispanic Neuropsychiatric Center of Excellence, the Equity for Latinx/Hispanic Healthy Aging and the Lifespan Assessment Through Integrated Neuropsychology Clinic address disparities in healthcare by offering bilingual training for medical professionals and conducting testing in patients’ native language.
Top Duke Basketball Recruiting Target Cancels Upcoming Visits
A top Duke Basketball recruiting target has cancelled some upcoming visits which signals good news for the Blue Devils.
RuneScape Reignited Cancelled Less Than Two Weeks After Being Announced
Creative director Mod Ryan announced that RuneScape Reignited, a new game mode designed for both old and seasoned players to start fresh, has been canceled less than two weeks after it was first announced.
Report: Cancelled “Assassin’s Creed Destiny” Unveiled in First Screenshots & Gameplay Footage
The Assassin’s Creed series is still on course to return to China for the first time since its modest 2.5D spin-off in 2015, now with the mobile-exclusive title Assassin’s Creed…
IAFF Center of Excellence welcomes new medical director, Dr. Kenneth Richter
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PUBLISHER’S NOTE: Busy Fall
We have a busy fall ahead of us—and that’s always good news. We like to stay busy. We’re working on two special annual publications: the CNY Business Guide and the CNY Winter Guide. Both publications are designed to reach specific audiences in the community. We’re excited about these new editions and would like to share a few details about them. Let’s begin with the Winter Guide. Winter can be challenging, but it also offers plenty to celebrate. The new CNY Winter Guide will help readers embrace the season and make it more fun and enjoyable. This year’s annual publication will feature an extensive calendar of events, compelling stories, and curated lists of things to do and see throughout the winter. This will be our 31st annual issue. It is one of the few publications—if not the only one—devoted exclusively to winter in Central New York. For advertisers, it offers a valuable opportunity to reach readers across the region. As we tell prospective advertisers, one ad works for them all season long. Rates start in the low $200s. The guide will be available at hundreds of high-traffic locations, including all Wegmans stores and select Price Chopper and Tops Friendly Markets locations. It will also be available online, with every ad hyperlinked so readers can click directly through to the advertiser’s website or Facebook page. Our network of drivers will also deliver the guide to hundreds of high-traffic locations several times throughout the winter. The publication will be out by Thanksgiving. The CNY Business Guide is a one-of-a-kind publication that many readers use as a reference. Unlike the books of lists published by business journals across the country, it comes in a glossy, full-color magazine format. It also ranks employers in four counties, with a particular emphasis on Oswego and Onondaga and substantial information about Cayuga and Jefferson. It is an ambitious project that requires extensive research, phone calls, careful fact-checking, writing and design. In short, it takes a great deal of work—and we’re glad to take on the challenge. The guide is widely distributed to business and professional readers throughout Central New York. The Business Guide gives companies an excellent opportunity to highlight their growth and expansion, showcase new products, and share other noteworthy developments. For readers, it provides a valuable snapshot of companies across the region, including what they do and who leads them. The guide will be published in early December. We invite companies to advertise in both publications. Advertising costs are relatively low, and each guide offers access to a broad audience across Central New York. Wagner Dotto is the editor and publisher of Oswego County Business Magazine.
HOW I GOT STARTED: Jim Brooker
Owner of Starlight MFG Solutions in Fulton was vice president at Otis Technology in Phoenix — until the company closed locally. He then decided to open his own shop. “We are pretty much doubling in size each year so far,” he says By Stefan Yablonski Q: When did you start this business” A: I started Starlight MFG Solutions LLC while I was working at another government contractor. I was vice president of engineering at Otis Technology at their Phoenix location until they closed that facility due to a shift in business at the end of 2023. While at Otis, I was also working on Starlight on a part-time basis. I gained a lot of exposure to a lot of different equipment. That is the kind of service we provided to Otis when we were a part of them. Now we have spun that whole concept off here. Q: How would you describe it? A: It’s a manufacturing engineering firm specializing in custom automation to serve as an outsourced engineering support for companies that need additional resources. I want to make it a sustainable business that can partner with local manufacturers to help them. Q: What is your background; did you go to college with this in mind? A: I am a graduate of Rochester Institute of Technology with both a bachelor’s and master’s degree. My B.S. from RIT was in manufacturing engineering technology and my MS from RIT was in manufacturing and mechanical systems integration with a minor in business. Q: Why this type of business? A: I identified a large gap in the market for companies that needed small to medium help with manufacturing projects. Q: What services do you offer? A: We are focusing more on manufacturing. We do a lot of robotics, we do laser marking, we do filling — pretty much anything that the customer needs. Q: Have you seen any growth since you started? A: Yes. We have been growing ever since the company started. Our specialties include robotics, vision inspection and guidance, rotary-indexing workcells, dispense systems, laser marking, machine tending and more. We provide support to companies that need additional resources. We moved to a facility in Fulton about a year and a half ago. We are leasing our space in Fulton — the former NET & Die facility. We bought our own equipment, we are leasing the space. We have been operating here since early 2024. Q: You’re ready to take on bigger jobs? A: We want to stay in the small to medium size market where the large players don’t want to play. That is kind of where we found our niche. We are expanding regionally to take on more of those projects. My customers are relatively small business. They don’t have in-house automation; engineering and development teams are not feasible. Q: Business has been doing well? A: I am pretty satisfied about where we are at. We are definitely growing year to year. We are pretty much doubling in size each year so far. We are self-sustaining. Q: How busy are you on any given day? A: How busy? That’s kind of relative. We average between three and five projects going on in the shop at any time. We have a backlog that is manageable. We have seen a great demand for laser marking. The work is very relationship-driven. Much of it is based on referrals from other customers. Q: So, you must have a pretty big staff? A: No. I have just one other full-time person, a colleague from Otis. I bring in other people as the projects dictate. I handle sales and the overall operation of the manufacturing processes. We use outside sources for some work. We aren’t afraid to take on the other jobs — but we are filling our niche pretty well. Q: Do you get tired? A: I don’t get tired, no not really. Before this I ran a facility in Phoenix for 12 years. I enjoy solving problems and that part of the job is still my favorite. I have a supportive family life at home that definitely helps a lot. I just love the challenge of it. Q: Do you still live in the area? A: Yes. I live in Phoenix, town of Lysander. Q: What is the biggest job you’ve done? A: We have done some that were pretty good size. I don’t want to get into dollar amounts, don’t want to share gross revenue. We try to use locally sourced components. It is just amazing the components you can find that are locally produced.
BUSINESS UPDATE: Port Perseveres Despite Tariffs’ Negative Impact
‘We are hanging tough ... in an environment that is incredibly difficult to do business in right now,” the port’s director says By Stefan Yablonski Tariffs imposed by the Trump administration have hurt the Port of Oswego by slashing Canadian aluminum cargo volumes and reducing revenue. “We’re doing good. We are hanging tough. It is a tough time for our line of business in general, you know with these tariffs and the amount of Canadian aluminum that we see through our docks,” said the new executive director, Tom Drumm. “Compared to 2025, we are doing exceedingly well in traffic coming in; not necessarily the volumes we were seeing, but yeah we are hanging tough in an environment that is incredibly difficult to do business in right now.” “I don’t know where people get these numbers to be honest. We have never publicly stated how much our revenue is down or up or left to right. We don’t have a strong sense of those revenue numbers until the shipping season really closes up. We won’t have an accurate picture of the revenue standpoint until after the shipping season, typically in late November,” he added. “What I can tell you is several of our Canadian vessels that carry the aluminum cells — the volume of aluminum on those vessels we have seen decreasing. That is attributed to a few factors. One is where Novelis is in in their restart process. Novelis is rocking and rolling right now. They are starting to pull a lot of aluminum from the port of Oswego, the aluminum that they roll down into coils. “Another factor plainly is the tariffs. Canadian aluminum is tariffed at 50%. So, on those vessels we are seeing lower numbers than we would like. We’d like to see vessels carrying roughly 10,000 metric tons of aluminum. Over the course of this year, we have seen more in the range of 4,000 to 6,000. “Every piece of that aluminum that we receive here by vessel at the port is from Canada and is subsequently hit with the 50% tariff. It directly affects us because we’ve received less volume than we would traditionally see pre-tariff times.” When the port receives less aluminum from those vessels it means less hours for the ILA (International Longshoremen Association) as far as folks that work on the dock, he said. When cargo declines, it affects everyone, fewer hours for longshoremen, fewer loads for truck drivers, fewer rail shipments and less business for local suppliers. “Outside of the aluminum that comes in by vessel, the port topped out at having roughly 4,600 aluminum ingots stored on site at the port. That project had never been done before. The port of Oswego had never had that many of those size ingots in our yard,” he said. “It has been a busy summer for the ILA. Would we like to see more work for them? Sure. They are working all those barges when they come in, but as opposed to working 15 hours they might be working seven or eight hours. It hasn’t been a distinct decline in ILA hours. There has been plenty of work to keep our guys busy throughout the summer.” More salt “We just brought salt back to the port in several, several years. Around Harborfest time at one point we had a salt barge here with about 24,000 metric tons of rock salt and we had an aluminum barge here the same week. We had close to 40 men working,” he said. “Yeah, the other products definitely keep us busy. The salt project was a massive project, one that we are proud of. I’ve got 24,000 metric tons of salt on site that has to go somewhere — that’s going to be another project.” It is important for the port to continue to look at different products, different commodities to try to diversify some of its revenue, he said, adding, “We have done a pretty good job of that in my first five months here … particularly with the rock salt we have on site right now. It is important to continue to try to stand out and work through some projects outside our usual business. I enjoy it. It is a challenge every single day we put our head down and we try our best.”
SPECIAL REPORT: Tough Business
A string of vacant restaurant buildings shows that many restaurants in the region are struggling — and several are closing By Stefan Yablonski [caption id=attachment_11132 align=alignright width=401] Smokey Bones Bar & Fire Grill on Route 31 in Clay closed its doors in April. It had been in operation since at least 2008.[/caption] By their nature, most restaurants have a limited life. An astonishing 60% go out of business within three years of opening, largely due to fundamental flaws in the planning of the operation. But even restaurants that experience years of success almost always face eventual closure. The restaurant business is very hard and because of both personal factors and external factors beyond anyone’s control, restaurants don’t last forever. For many restaurants, age is a big factor, according to Kenneth Walsleben, professor of practice, entrepreneurship and emerging enterprises at Syracuse University. “The owners have been at it for 20 or 25 years, if not longer, they want some time to themselves,” he said. Such was the case for Jocko’s Famous Ritz Diner in Oswego. Jocko Reitz bought the building in the late 1970s from Robert Shapiro. However, when he stepped away from the business, it eventually closed. [caption id=attachment_11142 align=alignright width=402] For nearly 80 years, Vona’s Restaurant passed through three generations of family in Oswego. It closed its doors on Dec. 31, 2025.[/caption] For nearly 80 years, Vona’s passed through three generations of family in Oswego. Vona’s Restaurant officially closed its doors on Dec. 31, 2025, when no family member wanted to take over. It is on the market. The Ruby Tuesday in Oswego operated for about two decades before permanently closing in April 2026. The restaurant faced multiple temporary health department closures in 2024 and 2025 due to persistent fruit fly and foundation pest issues. Management posted a final closure notice on the doors in mid-April 2026 and the building was put up for sale. The same pattern has been happening in Onondaga County. The big building once used by Smokey Bones Bar & Fire Grill on Route 31 in Clay remains empty, more than six months after the restaurant closed its doors in April. It had been in operation since at least 2008. [caption id=attachment_11130 align=alignright width=401] Ruby Tuesday in Oswego operated for about two decades before permanently closing in April 2026.[/caption] Just down the road from Smokey Bones, the popular Outback Steakhouse closed in August 2024. Another restaurant took its place, La Cocina Mexican Restaurant, but it closed shortly after. The building sits empty. Other very popular restaurants in the northern suburbs of Syracuse have recently closed. Among them, Fireside by the River in Baldwinsville and Primo Nestico’s Bistro Bar in North Syracuse. “I haven’t really paid attention to the Syracuse area. There has always been some turnover, but there probably has never been a tougher time to be a restauranter than now. It’s just brutal,” Walsleben said. In the first year, roughly 20% to 25% of restaurants close or change hands, according to the National Restaurant Association. [caption id=attachment_11122 align=alignright width=401] Outback Steakhouse closed in August 2024. Another restaurant took its place, La Cocina Mexican Restaurant, but it closed shortly after. The building sits empty.[/caption] “Depending on what statistics you look at, you’ll find that any business has a high mortality rate in the first year. That is just the nature of entrepreneurship,” Walsleben said. “There are certain ones that are getting hit hard while others are more fruitful. “And when you look at the restaurant industry you have to factor in labor which is a large part — typically a third of your expenses — and those costs are going up. And there is always turnover which means investing money to train people. Then you’ve got food costs, which is also a third of the typical restaurant budget. Since the pandemic labor has gone up 41%, food costs have gone up 35%. That’s a big tight squeeze righty there. That’s two-thirds of your budget that has gone up 35% to 40% in the last few years. And then the only way you can make that work is to raise the prices.” The National Restaurant Association reports menu prices are up 36% since February of 2020. In a survey released by the association, more than eight in 10 restaurant owners reported that their food, beverage and labor costs are now higher than before the pandemic. You have to deal with the reality of are the customers willing to pay for that? Walsleben added. Restaurants historically have very thin margins; their profit margin is about 5%. “You have a third that goes into food, a third that goes into labor and about 28%, 29% that goes into everything else — overhead, insurance etc. So that brings you down to your 5% leftover,” he said. “Everything is going up. Customer expectations are going up and people aren’t going to spend that much more. So, you have a tight squeeze here,” Walsleben continued. “Restaurants who use delivery apps, they pay a fee to those guys. Those guys don’t work for free. So, you can kind of see where the squeeze comes from.” Stuck in the middle There are pockets of opportunity; the two extremes of the market can make a profit. But the middle gets squeezed out. “If you are a low-end fast-food kind of place, there is room for that. People have changed their budgets. They are still going out, but they are not spending more,” according to Walsleben. “The high end remains positive. If you have a restaurant that brings a specific experience … a great food product or you are catering to high end customers who aren’t so budget conscious, those patrons are going to expect a high-end experience. They expect excellent food every time. They are expecting excellent service. If you can meet those expectations there is room for you at the top. It’s just the guys in the middle are getting the squeeze from both ends. Tough competition, customer expectations, costs are up. Menu items, you can’t raise the prices as much as you need to. That is why you are seeing a lot of restaurants baling out.” The ones that can adapt quickly are the ones who are doing OK. “Success is heavily dependent on the strength of a restaurant’s concept development and the planning of its execution. Eventually things aren’t always new. Things change. So, if you are in the restaurant business you have got to change your menu — keep things new, fresh and update your meals. It is very fickle industry. One year carbs are out, the next year berries are out. Everybody’s diet changes — constantly chasing the latest phase. You have got to adjust your menu and move with those modifications. If you have a static menu that you have used the last couple years that hasn’t changed except for the pricing, you’ve got a problem,” he said. A lot of times these buildings are singular purpose, he added. “You have a commercially viable kitchen and you got a seating area. There is not a lot of other businesses that cater to that type of a layout. So, it’s pretty common to see another restaurant slide in,” he said. One of the things a banker learns early on is you don’t lend money to restaurants … because they fail so quickly. It is very hard to predict who the winners will be. So, if you are a restaurant in addition to all the other challenges, it is very difficult to get loans, according to Walsleben. “You might work really well in the kitchen. But that doesn’t mean you are a great businessperson,” he said. “Restaurants can fail because the owner didn’t know how to manage things properly. There are a lot of challenges. “There is opportunity at the high end and the low end. But in the middle, that’s the death valley. There are just so many things working against you. You really need to have something that will pull people in and continue to pull people in because you to constantly have to change. Think about a theme and a product that is unique to the area people don’t travel that far these days you have to be able to deliver it in an innovative fashion and keep updating to keep people coming in the door.” Out of Business? How Fast? Do nine out of 10 restaurants fail in their first year, as commonly claimed? No. Survival analysis of 1.9 million longitudinal microdata for 81,000 full-service restaurants in a 20-year U.S. Bureau of Labor Statistics non public census of business establishments in the western US shows that only 17% of independently owned full-service restaurant startups failed in their first year, compared with 19% for all other service-providing startups, according to ResearchGate. The median lifespan of restaurants is about 4.5 years, slightly longer than that of other service businesses (4.25 years). However, the median lifespan of a restaurant startup with 5 or fewer employees is 3.75 years, slightly shorter than that of other service businesses of the same startup size (4.0 years). What Makes a Restaurant Successful? Opening and maintaining a successful restaurant is not as easy as creating a great menu and serving excellent food. It takes more than that, according to local restaurant owners who have been in business for decades in the region. They all agree that there are some guidelines to running a successful restaurant. • Quality food: Successful restaurants know exactly what they serve and who they serve it to. Delivering the same great taste every single time builds loyal customers. • Smooth operations: Friendly greetings and attentive staff make guests feel welcome from the moment they walk in. Hiring staff for personality and training for skill ensures reliable, caring service. • Smart marketing: Exceptional food and experiences naturally get people talking and sharing online. Word of mouth can help entice customers. Consistent social media and targeted advertising brings in new and repeat guests also. The menu is what keeps patrons coming back to Mimi’s Diner in Fulton, located at 201 N. Second St. “We locally source our produce and our meats. Our chicken and biscuits is a popular, popular special,” said Richard Tagliareni, the third-generation owner and general manager. “It’s all homemade. We have consistently served quality food.” His grandfather started the business more than 55 years ago. Mimi’s is engrained in the community. They cater to the community and are very involved in everything from the schools to local events. The first Mimi’s Drive-In opened in Mexico. Then a second in Oswego and then Fulton. Fulton’s Mimi’s is the only one left. “The last couple of weeks have been kind of slower than normal. October is usually a busier month for us People will start coming back around again. Also, the price of gas is affecting some things,” Tagliareni added. “We try to keep our prices in line. You go out to eat, you’re going to spend about a hundred bucks or so for two people for dinner. You come here to Mimi’s you are probably for two people for dinner it’s between $50 and $60. We are trying to keep our prices in line. We did have to increase our prices a little bit but things are looking OK.” For the Press Box, 29 E. First St., Oswego, it’s also about great food and a family atmosphere. “Our sports bar and restaurant was established in 1984,” said Alison Canale Scanlon, manager. “I think putting the time into everything makes a big difference and treating people like family when they walk into your restaurant. That’s how we have always operated since 1984.” “It’s the family oriented aspect,” she added. “Consistency, quality and presentation of our food — that’s the secret to a successful restaurant. We try to be very consistent with it. We treat people like family when they come in; because we know how we want to be treated when we go to a restaurant. We treat people the same or better.”
Mom-and-Pop Business Owners Grapple with Harsh Times
Report shows small business owners in NYS less optimistic about the economy. Taxes, inflation, labor costs and competition from larger businesses are major concerns right now, they say By Aaron Gifford [caption id=attachment_11067 align=alignright width=300] Ashley Ranslow is director for New York state at The National Federation of Independent Business (NFIB).[/caption] Owners of mom-and-pop businesses in New York state have been less optimistic lately than their peers in other parts of the country, a recent report indicates. The National Federation of Independent Business (NFIB), based on a survey of 11,000 of its members in the Empire State, reported that taxes, inflation, labor costs and competition from larger businesses are major concerns right now. “Indeed, while taxes are a major problem in New York and the United States overall, New York small businesses notably are struggling more with the state’s onerous, multi-level tax burden,” Ashley Ranslow, NFIB’s director for New York state, said in the July report. Compared with surveys of business owners in other states, far fewer New York respondents rated their businesses as in excellent or good health. The report also said labor costs here are about 25% higher than the national average and are the “single most important problem” facing businesses. One respondent to the New York-specific survey complained that too much red tape, taxes and laws that restrict high-yielding companies have stifled their operation’s growth. Others said high disability and workers’ compensation insurance costs, alarming increases in utility rates and excessive building regulations are discouraging. Statewide, New York has a gross domestic product of $2.53 trillion (third in the nation, followed by Texas, $2.90 trillion; and California, $4.25 trillion), a per capita income of $90,500 (sixth) and an unemployment rate of 4.6% (34th). There are 2.4 million small businesses that employ 3.9 million people. [caption id=attachment_11112 align=alignright width=451] Member of the Greater Liverpool Chamber of Commerce gather at one of the several functions the chamber organizes monthly. “Everyone in this business community encourages each other to shop local. Everyone just wants to see each other succeed,” says Megan Wilmot, the chamber director[/caption] “New York state boasts one of the largest, wealthiest and most diverse cities in the world — and that’s still only about half the state’s population,” the report said. “In other words, the state is both its iconic city and so much more — geographically, demographically, economically. But New York is not without its challenges, challenges that include notably high taxes and other weaknesses that impact the small business environment,” it said. The report includes an optimism index that compares responses from New York (NFIB) members with those of their peers in other states across several categories. This ranges from plans to increase employment to expectations for higher sales, to plans to increase inventory or expand. The scores for Empire State business owners were lower in most categories, but they did score higher than the national average in noting that they have current employment openings, and that they are hopeful that the economy will improve. “The metrics so far paint a picture of a state with a series of challenges for small businesses, from a slightly below national average Optimism Index to a more seriously below national business health to very substantially below national Employment Index. What is going on with businesses that are creating these differences?” the report stated. In Central New York, the regional labor force comprises nearly 398,000 workers. The median household income here is $71,463, and the gross domestic product for the region last year totaled $61.3 billion, according to the CenterState CEO economic development and research organization. About half of the region’s labor force works for small and mid-sized businesses, although the number of people employed in that sector has decreased by 7% since 2010, according to CenterState’s 2026 economic forecast report. “While record-high employment in large-scale enterprises provides a strong foundation for Central New York,” the report says, “the long-term health of communities depends on a thriving small business sector to serve as a stabilizer.” Area employers identify several barriers to Central New York’s anticipated growth, including lack of specialized or skilled workers, government regulations, unaffordable housing options and long-term construction disruptions. In the city of Syracuse, the number of jobs in retail trade decreased by 1,500 or 4.7% between July 2025 and this past July. By contrast, the number of jobs in the leisure and hospitality sector increased by 2.5% or 700 jobs, in the same annual period, according to the New York State Department of Labor. Still, there’s plenty of interest for new businesses across Central New York. U.S. Census figures show that the number of applications for new businesses in all four counties increased significantly in the past 20 years. In Cayuga County, there were 324 applications in 2005 compared to 470 last year. In Madison County, the number increased from 385 to 480; Onondaga County, from 2411 to 4132; and Oswego County, from 553 to 836. Downtown Cazenovia is exemplary of Madison County’s trend: In the past year, the village welcomed a bait shop, a thrift store, a vitamin infusion center, a pizzeria, a Pilates studio and an Italian restaurant. A candy store is scheduled to open on the main drag in the months ahead. Oswego’s list of interesting new businesses in the past year includes a bubble tea shop, a hot dog eatery in Fulton, a specialty grocery store that features New York state products in Mexico, a beauty and esthetics studio in Hannibal and a hardware and farm supply store in Sandy Creek. In Onondaga County, the Liverpool area has also enjoyed a steady stream of new shops and eateries in recent years. That suburban community is unique in that, unlike neighboring communities, most of the restaurants are family-owned and not part of a national chain. [caption id=attachment_11116 align=alignright width=300] Megan Wilmot is the executive director of the Greater Liverpool’s Chamber of Commerce.[/caption] Megan Wilmot, executive director of the Greater Liverpool Chamber of Commerce, said independent business owners in her community maintain a strong sense of pride in holding their own against national companies. The chamber helps boost morale with red carpet events, ribbon cuttings, coffee hours and five-year anniversary celebrations for participating businesses. “We have built such a strong community,” Wilmot said. “Everyone in this business community encourages each other to shop local. Everyone just wants to see each other succeed.” In Syracuse, the downtown retail occupancy rate last year was about 82%, a slight improvement from 2024, according to the Downtown Syracuse Committee’s most recent annual report. Buildings with the largest amount of vacant space included The Galleries, One Park Place, and Equitable Towers, though not all of those spaces are designated for retail use. New businesses that opened in downtown Syracuse last year: Better with Time Clothing, Dakshin Curry & Biriyani, Havana Tattoo Society, Milano Bean Café, Miss Daisy, Pausa Coffee, Sweets for Babe, The Society CNY and Yafah Beauty Studio. The Destiny USA mall’s occupancy rate decreased from 80% in 2023 to 72% by the end of 2024, according to Integra Realty Resources. That leaves more than a quarter of the mall’s retail space vacant. “Looking ahead, the retail market is expected to see minimal rent growth, with vacancy rates likely remaining stable in community and neighborhood centers but continuing to rise in enclosed malls,” Integra’s report said. “New construction activity is low and redevelopment plans for former malls like Shoppingtown and Great Northern are still in the planning stages. The proposed Micron chip plant may spur development, but challenges remain in finding co-developers for large-scale projects.” Nationally, the U.S. Chamber of Commerce expects that small businesses will remain resilient and see their sales and revenues eventually improve. That organization, in a recent national survey, found that 25% of small business owners expect the economy to improve in 2027, while 45% indicated that they plan to increase employment in the next 12 months. And 69% said they believe their small business is in good shape and 70% said they are comfortable with their current cash flow. Thirty-one percent of small businesses reported raising their prices in July and 28% are planning to raise their prices within the next three to four months, the report said. Twelve percent indicated that this is a good time to expand their business. “Small business owners voice optimism for future revenues and hiring,” the report said. “High costs continue to be a wet blanket on reinvestment.” The NFIB reported in July that Main Street, despite gas price hikes, “is OK … for now.” Its small business economics trend report said sales across the country have been strong compared to last year, but continued inflation and higher prices from mom-and-pop establishments are causing some “cracks” to show. “If costs stay this high for much longer, reduced investment will have a tangible economic impact,” the report said. “The status quo is OK, but the outlook? The outlook is uncertain.”
Broward Health Medical Center Introduces Bispecific T-Cell Engager Therapy for Cancer Patients - Florida Hospital News and Healthcare Report
OCTOBER 13, 2026 – Broward Health Medical Center has introduced bispecific T-cell engager (BiTE) therapy, an innovative immunotherapy that harnesses the body’s immune system to target and destroy cancer cells. […]