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Chandler pub, central Phoenix brunch spot dinged for health violations
Jason Barry reports on the Valley restaurants that did not make the grade for October 21, including some popular chains and bars.
Ray Archuleta, Barry Fisher, Jim Moseley and more soil health presenters
By Randall Reeder, Ohio No-Till Council Ray Archuleta will present two days: Nov. 10 in Columbiana and Carroll Counties, and Nov. 11 at the Brandt Farm in Fairfield County. Other key presenters will also be on those programs. Ray Archuleta, an internationally known soil scientist (retired from
'Office Space' star Richard Riehle dies at 78
Actor Richard Riehle arrives at the premiere of New Line Cinema's 'A Very Harold & Kumar 3D Christmas' at Grauman's Chinese Theatre on November 2, 2011 in Hollywood, California. (Jason Merritt/Getty Images)Richard Riehle, known for his role in the 1999 film Office Space, has died. He was 78.A statement shared by Artists & Representatives and Wright Entertainment, Inc. announced Riehle's passing on Monday, writing, "Our industry has lost an exceptional talent, and our community has lost a truly wonderful man.""We are deeply saddened to confirm the passing of our beloved client, Richard Riehle, this past weekend," the statement said. "A remarkable actor whose career in theater, film, and television spanned nearly five decades and more than 400 projects, Richard leaves behind an extraordinary legacy."The statement continued, "Beyond his immense talent, he will be remembered for his genuine goodness, boundless kindness, and unwavering generosity, particularly toward emerging actors and filmmakers, whom he encouraged and supported at every opportunity."Born on May 12, 1948, Riehle starred in many television series and films over the years.Notable projects include Casino, The Man from Earth and Deuce Bigalow: Male Gigolo.He got his start as an actor at the University of Notre Dame, where he was involved in the University Theatre and starred in several stage productions. He went on to earn a Master of Fine Arts in acting and directing from the University of Minnesota.While he's played characters that have an "average Joe" presence, he always made the most of his brief screen time.Some roles that he is remembered for include The Quartermaster in Glory, the train guard in The Fugitive, Reverend Scroggins in Fried Green Tomatoes and Bill Cozbi in Bridesmaids.On television, he starred as Principal Ed Rooney in the 1990 series Ferris Bueller and as grandfather Walt Finnerty in the early 2000s sitcom, Grounded For Life.In 2023, he also played Warden Reynolds in Barry.Riehle is survived by his wife, Jane Latham, and their four children.Copyright © 2026, ABC Audio. All rights reserved.
Captain Price Actor Sends Message to Fans as Call of Duty: Modern Warfare 4 Campaign Praise Rolls in
Barry Sloane, the actor behind Call of Duty's Captain Price, has shared a message with fans as praise for Modern Warfare 4's campaign rolls in.
In 'Bucks County, USA,' a community torn apart by politics tries to heal
The five-part docuseries on PBS, co-directed by Robert May and Barry Levinson, aims to find common ground between community members in a purple county in Pennsylvania.
Alison Gladowsky
Rivkin Radler Managing Partner Barry Levy announced that Alison Gladowsky, an accomplished attorney with more than 20 years of experience, has joined the
Dewsbury-Hall Shows Leadership at Everton With Thierno Barry Comments
Everton midfielder Kiernan Dewsbury-Hall has been discussing his relationship with Thierno Barry, following the draw with Hull City in the Premier League on Sunday.
Barry Manilow walks off stage after two songs, cancels weekend shows
After returning from a hiatus, Barry Manilow abruptly stopped his Las Vegas concert after just two songs and nixed weekend performances because of health issues.
Health Fair Miami
Gabrielle Carter, a student at the Barry University School of Podiatric Medicine, cleans feet during the annual foot washing and health fair held by the Dade County Street Response at
Barry Manilow's comeback stymied by more health issues
Barry Manilow's comeback has been cut short.
Barry Manilow returns to the stage after six-week hiatus following health break
"I'm back!": Barry Manilow returned to the Las Vegas stage after six weeks away, a summer break while he is navigating his lung cancer recovery.
Barry Manilow returns to the stage after six-week hiatus
"I'm back!": Barry Manilow returned to the Las Vegas stage after six weeks away, a summer break while he is navigating his lung cancer recovery.
Aboriginal historian Barry Corr vividly investigates colonisation – but is less convincing on politics
What right did settler society have to intervene in Aboriginal life? The humanitarian tradition has no adequate answers, says Barry Corr.
Finalists named for Nistler College of Business & Public Administration deanship
Open forums will be held Oct. 5, 7, 12 and 14 in Nistler Hall’s Barry Auditorium.
Business management expert urges farmers to focus on liquidity and cost control heading into 2027
A production business management expert says preserving liquidity and managing working capital will be critical as producers face another year of tight margins. Barry Ward with Ohio State University Extension says stronger corn and soybean prices have improved the profit picture for 2026, but… “We’ve got elevated cost structures that we’re not going to be […]
Hampton Roads museums undergo expansions
Barry Art Museum at ODU and Virginia MOCA expand galleries and event spaces, boosting Hampton Roads' arts scene with new exhibitions and community programs.
Then and Now: Graves helps clients buy, sell businesses
Barry Graves has brokered more than $1 billion in deals across Arkansas, Oklahoma and Missouri. As executive broker at Cantrell-Griffin Business Brokers he helps business owners navigate the decision of...
Jess McKenna and Zach Reino are a force to be toured with
Known for their work on an improvised musical podcast and Dropout TV, this duo brings “Off Book” to the Barrymore in Madison on Oct. 17.
Tripp Skipper: Barry Moore is going to Washington. Abdul El-Sayed shows what he’ll be fighting
And there may be no clearer illustration of the ideological fights awaiting Congressman Barry Moore in the United States Senate than Abdul El-Sayed.
These Phoenix-area restaurants miss the mark on health scores this week
A Little Caesars in Mesa and SoCal Fish Taco Company in Gilbert are among Valley restaurants on this week's Dirty Dining. Jason Barry reports.
These Phoenix-area restaurants miss the mark on health scores this week
A Little Caesars in Mesa and SoCal Fish Taco Company in Gilbert are among Valley restaurants on this week's Dirty Dining. Jason Barry reports.
These Phoenix-area restaurants miss the mark on health scores this week
A Little Caesars in Mesa and SoCal Fish Taco Company in Gilbert are among Valley restaurants on this week's Dirty Dining. Jason Barry reports.
These Phoenix-area restaurants miss the mark on health scores this week
A Little Caesars in Mesa and SoCal Fish Taco Company in Gilbert are among Valley restaurants on this week's Dirty Dining. Jason Barry reports.
These Phoenix-area restaurants miss the mark on health scores this week
A Little Caesars in Mesa and SoCal Fish Taco Company in Gilbert are among Valley restaurants on this week's Dirty Dining. Jason Barry reports.
David Spade wants to ask Drew Barrymore if they’ve ever made out: ‘I don’t know if we did’
Now this sounds like a question for Drew’s News!
Actall Appoints Barry Prestage as Business Development Director
Real-time location systems provider Actall Corporation has appointed Barry Prestage as Business Development Director.
'A really positive start for Barry'
Thierno Barry has been the surprise hit of Everton's season so far, with the 23-year-old striker the match-winner against Ipswich to take his tally to five goals this season. It is a marked improvement in scoring ratio from his eight goals in 41 games last season - and BBC Sport Merseyside commenter Chris Coughlin believes Barry is becoming a favourite with fans. It is Everton heritage and an honour to wear the number nine.
“Rain Man” Director Barry Levinson’s New Doc Shows How Politics Tore Apart an ‘Idyllic’ Pennsylvania Town (Exclusive)
“You wanna be a Republican, you wanna be a Democrat. Okay. But does that mean we can’t communicate?,” Levinson tells PEOPLE while discussing ‘Bucks County, USA’
A former Australian miner spotted a ripple on Saturn from his backyard in 2024; two years later, he co-authored a world-first discovery of a 10-sided atmospheric wave
A mysterious ripple spotted on Saturn from an amateur astronomer's backyard in Australia has helped lead to the identification of a giant, 10-sided atmospheric wave around the planet's south pole. Trevor Barry, a former miner from Broken Hill, New South Wales, had been observing Saturn from his homemade backyard observatory when he noticed an unusual feature in 2024.
Health officials clear part of Hastings apartment building after ricin exposure
In a letter health consultation dated Sept. 15 and addressed to Barry-Eaton County Health Department Health Officer Rebekah Condon, MDHHS concluded that first floor apartment units 101 through 113 and the connecting hallway from unit 113 to the south stairwell no longer pose an imminent danger to life and health from ricin.
Barry-Eaton health officials to provide update on ricin exposure at Hastings’ Tyden Lofts
The Barry-Eaton District Health Department is expected to provide an update Monday on a ricin exposure that prompted the evacuation of Tyden Lofts in Hastings.
Ross Mathews talks ‘The Drew Barrymore Show,’ growing up in WA
During a recent visit to Seattle, the "Drew Barrymore Show" co-anchor discussed his early life and career success. The talk show's new season premieres Monday.
Giants Lose Devers for Season After Playing Through Injury
Rafael Devers heads to the Injured List for core surgery, ending a gritty first full season with the San Francisco Giants, marked by 37 home runs and the team's best power numbers since Barry Bonds.
TNS top after Iddenden hat-trick inside five minutes
Abbie Iddenden scores four as The News Saints thump Barry Town United 9-1 to move top of the Adran Premier.
Rafael Devers Approaching Barry Bonds’ San Francisco Giants Record
Despite his team’s season-long struggles and his own early-season slump, Rafael Devers is having one of the best seasons a San Francisco Giants hitter has had in a long time.With a strong finish to the season, Devers can break a franchise record held by Barry Bonds.Rafael Devers Closing in on Record From Barry Bonds’ Historic […] The post Rafael Devers Approaching Barry Bonds’ San Francisco Giants Record appeared first on HEAVY.
Testing confirms ricin exposure at Hastings apartment complex, health officials say
The Barry-Eaton District Health Department (BEDHD) has confirmed a ricin exposure at Tyden Lofts in Hastings.
Barry Alvarez assess impact of Wisconsin's new indoor facility
Former UW athletic director Barry Alvarez shares his thoughts on the Kellner Family Athletic Center during the facilty's ribbon cutting ceremony Sept. 11, 2026.
Barry I. Levy
Rivkin Radler Managing Partner Barry I. Levy works hand in hand with institutional and individual clients to navigate complex litigation in the insurance, healthcare and financial services arenas.
Injury-hit Cardiff weighing up free-agent options
Cardiff City are continuing to monitor the free-agent market as an injury-hit squad leaves head coach Brian Barry-Murphy short of options.
Robertson relishing deeper role with Bluebirds
Midfielder Alex Robertson has praised Cardiff City's coaching staff for helping him settle in a deeper role. The Australia international, who made 38 appearances last season, has been asked to play further back by boss Brian Barry-Murphy and is enjoying his new responsibilities.
‘Bigger than any team’: Legendary hockey broadcaster Barry Melrose dies at 70
Barry Melrose, a hockey player-turned-coach who led the Los Angeles Kings to the 1993 Stanley Cup Final before going on to a long career in broadcasting the sport, has died
Legendary ESPN hockey analyst Barry Melrose passes away at 70
The hockey world has been dealt a tragic blow as iconic ESPN hockey analyst Barry Melrose has passed away. ESPN made the announcement on Wednesday evening. Melrose spent a lifetime in hockey as a player, coach, and television analyst. He played over 300 games in the NHL as a defenseman in the 1970s and 1980s.…
Gascoine transforms a pottery hobby into thriving Monson business
MONSON — More than a quarter century ago Jemma Gascoine noticed an ad for an evening pottery class when she flipped through a copy of “Time Out London” magazine someone had left on a seat of the London train back in her native United Kingdom. Gascoine soon stopped by a class offered by Barry Guppy and attended his workshop classes for two years.
All 7 ‘Scream’ movies, ranked from worst to best
For nearly 30 years, ‘Scream’ has terrified, entertained, and satirized multiple generations of horror fans. See how all seven movies rank from worst to best.
$20K Hustlers: 1994 Budget Sports Coupes Compared
Blistering performance costs less than one game’s play for Barry Bonds.
Barry Manilow announces hiatus days after canceling third show
Barry Manilow has announced he needs to step away from the stage to recover after a busy summer tour. The 'Copacabana' crooner canceled three shows this month, citing 'technical difficulties' among other issues.
Climate change on tap at Siberia as part of science series
Siberia’s ‘Science Time’ series blends nightlife and discussions with scientific experts and researchers. The upcoming edition of the series will feature a lecture on hurricanes and climate change and Q&A with LSU Health New Orleans professor and former state climatologist Barry Keim.
Cardiff boss Barry-Murphy wants busy end to window
Head coach Brian Barry-Murphy hopes Cardiff City will be very busy in the final week of the transfer window as he looks for reinforcements to solve their defensive injury crisis.
Barry Manilow taking 'quick break' from touring amid health issues
Barry Manilow was "pushing a little too hard" during recent gigs and is taking some time out to recuperate.
Packers Practice Erupts in Fight Between Former Texas Teammates
Packers practice boiled over when Matthew Golden and Barryn Sorrell got into it. The post Packers Practice Erupts in Fight Between Former Texas Teammates appeared first on HEAVY.
Osho injury leaves Cardiff vulnerable - Barry-Murphy
Head coach Brian Barry-Murphy says his Cardiff City squad is "vulnerable" after centre-back Gabriel Osho joined their list of fitness concerns.
Barry or Beto? How should Everton's XI look?
Speaking to BBC Radio Merseyside, Everton fan Natalie Bargery has picked her XI for the Crystal Palace fixture at Hill Dickinson Stadium on Saturday. Bargery described Branthwaite as the "first outfield name on the teamsheet" and added he is in "100%" of Evertonians starting line-ups.
$15M jury verdict after radiologist improperly places catheter, leading to patient death
Radiologist Barry Jeffries, MD, allegedly improperly placed a suprapubic catheter outside of the patient's bladder, worsening his chyle leak.
VHC Health gets record-breaking $17.5M donation, supporting new cancer center
A $17.5 million donation to VHC Health, the largest philanthropic gift in the organization's history, is supporting a new cancer center expected to open in 2028. VHC Health is renaming its outpatient pavilion the "Arlene Evans and Barry Dewberry Outpatient Pavilion" in honor of the donors, who previously contributed $3 million to the hospital that
Wingers and defenders needed with tough season ahead
After Saturday's EFL Cup win over Swindon, we asked Cardiff City fans what manager Brian Barry-Murphy's promoted side still needs for the Championship season which kicks off against Wrexham on Monday. Mark: Unless Cardiff bring in at least another three or four players we will be in a dog fight at the wrong end of the table. Dafydd: The Championship looks really tough this year.
Upcoming PBS docuseries, 'Bucks County, USA,' to examine suburbs' political division
Filmmakers Barry Levinson and Robert May delve into community tensions in the political battleground. The first episodes premiere Sept. 20.
Detroit sports heroes to tee it up at DGC, and fans can watch for free
Wednesday's Rocket Classic pro-am will include Lions legends Barry Sanders and Calvin Johnson. Admission and parking are free.
‘Profoundly corrupt’: The EU’s leading FIFA critic sharpens his attack - Live Updates
European lawmaker Barry Andrews savages the world football governing body after U-turn on American star's suspension.
Star-maker Clive Davis honored at funeral that draws Bruce Springsteen, Dionne Warwick and others
Kenny G played a mournful sax solo to kick off the funeral for music legend Clive Davis. Pop music royalty, including Bruce Springsteen, Barry Manilow, Stevie Wonder and Dionne Warwick,
Making Our Own Luck
We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.
Clive Davis, music titan behind Whitney Houston, dies at 94
Clive Davis, one of the most influential record moguls in music history and the mastermind behind the careers of Whitney Houston, Barry Manilow, Earth, Wind & Fire, Alicia Keys and
Don’t wear these items to Barry Manilow’s Las Vegas show
An impressionist tried to wear a Barry Manilow wig and jacket to meet Barry Manilow. Bad idea.
SGMC Health Welcomes Barry Fleming as Director of Main Emergency Department
SGMC Health welcomes Barry Fleming as Director of the Emergency Department at SGMC Health Main.
Trump-backed U.S. Rep. Barry Moore battles ex-Navy SEAL Jared Hudson in GOP Senate runoff in Alabama
The Alabama race will be another test of Trump's endorsement powers, as his picks have largely prevailed in Republican primaries this year.
Trump-backed US Rep. Barry Moore battles ex-Navy SEAL Jared Hudson in GOP Senate runoff in Alabama
Alabama voters are deciding party nominations for an open U.S. Senate seat
American family moved to Thailand with young kids; more time together
Clea Barry says she and her husband talked to their kids about the move by showing them YouTube videos about fun things they could try in Thailand.
Houston Rockets jersey history No. 17 - Brent Barry (2008-09)
During his time suiting up for the Rockets, Barry wore only jersey No. 17 and put up 3.7 points, 1.7 rebounds, and 1.4 assists per game.
“Every Year After” showrunner has a 5-season plan for the series
"I think Barry's Bay has a lot more story to tell."
'Every Year After' showrunner has a 5-season plan for the series
'Every Year After' showrunner Amy B. Harris has big plans for Barry's Bay, including a season 2 that will adapt Carley Fortune's 'One Golden Summer.'
IU College of Arts and Sciences students recognized by Goldwater Scholarship program
Two students from the College of Arts and Sciences at Indiana University Bloomington are recipients of the prestigious Barry Goldwater Scholarship, a nati...
Nutrition professor fights against unhealthy habits
Barry Popkin’s groundbreaking research on the dangers of sugary drinks, processed foods and inactivity has improved lives worldwide.
Barry Diller’s People Inc. Plans a Takeover Bid for MGM Resorts
The mogul’s People Inc. is preparing an offer to buy the portion of the casino giant that it doesn’t already own, at an $18 billion valuation.
Watch Remembering the Life and Work of Jonathan Clements: Masters in Business
Barry sits down with Jason Zweig and William Bernstein. They discuss "Money and Me" the last book of author and journalist Jonathan Clements. Jason and William also examine Clements's approach to personal finance and impact to financial journalism.
Cardiff pair in BBC's League One team of season
Cardiff City defenders Joel Bagan and Dylan Lawlor have been named in BBC Sport's League One team of the season. Both players are graduates of the Bluebirds academy and played a key role as Brian Barry-Murphy's side secured an instant return to the Championship. Bagan, 24, scored once in 52 games in all competitions during the season and recently signed a new four-year contract with Cardiff.
Marshall’s Elli Barry Taking Part In NCAA Career In Sports Forum
Marshall Volleyball's Elli Barry is currently in Indianapolis taking part in the NCAA Career in Sports Forum, which runs from May 27-30 at the NCAA Headquart...
25 years ago click chemistry changed science. What happened next?
Barry Sharpless and his team first introduced the concept of 'clicking' molecules together 25 years ago
Is it getting windier in Kentucky?
Is it getting windier? Long-time listener Barry Zalph thinks it is, at least in Louisville. And he’s not the only one. Redditors and local reporters have noticed a recent uptick in the region’s windstorms, too. But does that point to any larger trends in windiness? And if so, what could be causing it? We talked to meteorologist and extreme weather specialist Scott Gunter to find out. Plus, we dig into whether Tornado Alley is shifting into Kentucky as the climate warms. This episode is part of Nature Quest, our monthly listener-driven segment about climate and the environment. Have a question for us? Send a voice memo to shortwave@npr.org with your name, location and what you’re noticing in the environment around you… it could be our next Nature Quest!Interested in more weather and wind science? Email us your question at shortwave@npr.org.Listen to every episode of Short Wave sponsor-free and support our work at NPR by signing up for Short Wave+ at plus.npr.org/shortwave.
What Norway’s dominance at the Winter Olympics can teach us about youth sports
The country’s focus for young people on ‘the joy of sport’ leads to much higher participation rates – and lots of Olympic gold Barry Finegold, CommonWealth Beacon EVERY CYCLE OF the Winter Olympics brings a familiar but uncomfortable storyline: The United States, with its vast population, enormous resources, and deep
Mallon Receives Inaugural Dawn Staley Legacy Award at Philadelphia Sports Legacy Honors
PHILADELPHIA - Janet E. & Barry C. Burkholder Family Head Women's Basketball Coach Amy Mallon was one of six recipients of the inaugural Dawn Staley Legacy A...
'Brady Bunch' star Barry Williams says it took 15 years to make peace with fans calling him 'Greg': 'It was a threat to my identity'
'Brady Bunch' star Barry Williams says it took 15 years for him to make peace with fans calling him 'Greg' in public: 'It was a threat to my identity.'
Alabama Rep. Barry Moore, former Navy SEAL Jared Hudson advance to GOP runoff in Senate race
Moore, boosted by the Trump endorsement, led the GOP primary voting Tuesday night for the seat being vacated by Sen. Tommy Tuberville, who is running for governor.
Sports promoter Barry Hearn to receive civic honour
The sports promoter and founder of Matchroom says he is "honoured" to be awarded the title.
Kyle Schwarber joins Barry Bonds, Mark McGwire in MLB history
The Phillies' slugger continues to etch his place in the history books as he finds himself in the company of Barry Bonds and Mark McGwire.
Longtime KOAT health expert Barry Ramo awarded UNM honorary doctorate
Longtime KOAT health expert Barry Ramo was awarded an honorary doctorate from the University of New Mexico due to his decades of contributions in promoting heart health.
Matchroom sells minority stake to US investment firm Bruin Capital
Barry and Eddie Hearn’s sports promotional company is reportedly valued at more than £1bn
11 TV Hill: Making Baltimore an entertainment destination
Big-name artists like Barry Manilow, Olivia Dean and J. Cole are coming to CFG Bank Arena this year, highlighting a push to bring major acts to Baltimore.
'Comedy Bang! Bang!' brings ‘Ground Beefing’ to Madison
The popular comedy podcast features performers improvising fake characters. Host Scott Aukerman is bringing the show to the Barrymore Theatre May 27.
Barry Manilow postpones shows for fourth time in 5 months
The iconic singer underwent surgery for lung cancer in December.
How Perimenopause Became America's New Health Scare
If you’re a woman who speaks English, it sometimes feels like you can’t spend time on the internet without being bombarded with all the ways in which your body or your mind could be just a little broken. A few years ago, Instagram was full of women talking about attention deficit disorder, and lo and behold: From 2020 to 2022, the percentage of women (between the ages of 23 and 49) newly diagnosed with it nearly doubled. Not long ago, premenstrual syndrome was all the rage, with the algorithm pushing videos that explained why it’s okay to fly off the handle once a month. These days, the word perimenopause is everywhere. Perhaps you’ve seen the headlines. “Perimenopause is having a millennial moment. Here are 7 ways to cope,” says The Washington Post. Or perhaps you’ve seen Apple TV’s glossy drama Your Friends & Neighbors, which is back for its second season; the female protagonist Mel is explicitly perimenopausal, and in the first season, she keyed a car for no apparent reason. She’s played by Amanda Peet, who talks about being perimenopausal in real life (“God knows I’ve wanted to key a lot of cars in the last three years,” she’s said.) In fact, it sometimes feels like every celebrity interview with a forty- or fiftysomething woman requires her to open up about what’s going on with her hormones. Drew Barrymore joked on CBS Mornings that when she found out how long perimenopause can last, she thought she’d “never make it 10 years like this.” Katherine Heigl told Business Insider that “whoever designed it so that women would be going through perimenopause while raising teenagers should be sent a strongly worded letter.” At the same time, influencers who talk about perimenopause seem to have cropped up out of nowhere with something to sell you, causing people online to wonder where this all came from. It’s trickled down from Instagram to tchotchke shops, which sell fridge magnets that say “Perimenopause Is Hot.” You can buy a T-shirt that proclaims “Perimenopause Made Me Do It!” My mom, who is 48, started uncontrollably shaking her leg at night a few years ago. “It’s perimenopause,” she told me when I complained about how annoying it was. But what exactly is perimenopause—and why are we all talking about it all of a sudden?
Analysis: VAR frustration for Toffees
It isn't that long since Everton were in West Ham's position and fighting for Premier League survival - but now they are in the battle to secure European football next season and, particularly for that reason, this will have been a frustrating result. David Moyes' side have one of the best away records in the Premier League and it looked they would earn a point with Kiernan Dewsbury-Hall's late strike. Moments before Dewsbury-Hall equalised, the Toffees thought they had a penalty when the ball struck Mateus Fernandes' hand inside the box as he grappled with Thierno Barry.
Barry Mano, Who Gave Sports Referees a Voice (and More), Dies at 82
With Referee magazine and a nonprofit advocacy group, he created a community and support system for sports officials
Why CBS Remains Bullish on Syndicated TV Shows
The head of CBS Media Ventures, Bryon Rubin, breaks down why the subsidiary’s lineup of game shows, courtroom shows and a daytime talk show makes business sense in 2026.
UCF receives $50 million from business alum, largest gift in school history
Barry Miller’s gift will help the business college hire new faculty members in fields such as artificial intelligence and cyber security.
First-Gen Alumnus Behind Transformational Gift Believes in Power of Philanthropy to Change Lives
With a $50 million gift, entrepreneur Barry Miller ’95 is investing in the next generation of Knights — helping them build the skills and connections that have fueled his success.
UCF Receives $50 Million Gift to Establish the Barry S. Miller College of Business
The largest gift in university history positions UCF to lead the future of technology-driven business education.
AD Chris McIntosh is reportedly leaving Wisconsin for role in Big Ten office
According to two reports, Chris McIntosh, Barry Alvarez's successor as athletic director, is leaving Wisconsin for a job with the Big Ten Conference.
Alamo Drafthouse showing 'The Pitt' finale free for health care workers
Ten Alamo Drafthouse locations are hosting free screenings of "The Pitt" Season 2 finale on Monday, April 13. Limited tickets are available online.
How Trump’s ‘wall of noise’ is changing Australian politics – Back to Back Barries podcast
Tony Barry and Barrie Cassidy discuss the fragile ceasefire in Iran and the pressure building on Australian politicians to respond to Donald Trump’s escalating rhetoric.
Two Carolina juniors named 2026 Goldwater scholars - College of Arts and Sciences
Anish Aradhey and Paul Hamrick, both juniors at Carolina, were selected for the prestigious Barry Goldwater scholarship. Established by Congress in 1986, the scholarship is designed to identify and support the next generation of research scientists.