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Zingerman’s Cornman Farms gets new owners who plan to add 14-acre vineyard
The owners of Social Vines Vineyard & Winery plan to keep the Cornman Farms name and continue to operate it as an event venue.
America’s biggest measles outbreaks have very different death tolls. Why?
Outbreaks in Pennsylvania, South Carolina, Utah, and West Texas have produced dramatically different numbers of deaths.
Ana Navarro shuts down ‘View’ cohosts for joking during tense Donald Trump discussion topic
Ana Navarro shut down ‘The View’ cohosts Sara Haines and Alyssa Farah Griffin for making light of a serious, tense topic related to Donald Trump: ‘Stop, this is not funny.’
Country star Thomas Rhett returning to Omaha for CHI Health Center show
Thomas Rhett will perform at 7:30 p.m. on Saturday, Oct. 24 at the CHI Health Center in Omaha.
Vernon County expands support for small businesses through grant program
15 Vernon County businesses have been awarded $10,000 each through the 2026 Elevate Vernon Grant Program.
Training solutions for your business
Director of Workforce Development and Continuing Education Programs Molly Salisbury joins Kerrigan to share how you can build your team's skills with training designed around your organization's needs.
Training solutions for your business
Director of Workforce Development and Continuing Education Programs Molly Salisbury joins Kerrigan to share how you can build your team's skills with training designed around your organization's needs.
CBS Sports projects Florida for Citrus Bowl after Week 7 Texas win
After securing a signature road win over Texas in Week 7, CBS Sports now projects Florida football to play in the Citrus Bowl against Iowa.
Opinion: Chicago can’t cut its way out of this budget crisis. There’s another option.
To solve Chicago’s financial crisis, we need to look past the false binary between cutting our way out, and regressive fines and fees.
Trump uses antisemitic slur to defend GOP Kansas senator
GOP Kansas Sen. Roger Marshall Marshall is locked in an unexpectedly tight reelection battle against Democrat Adam Hamilton in what might be the biggest surprise of the midterms.
Political Pulse: Independent candidate Rep. Peri Pourier runs on public safety for District 27 Senate
Independent candidate Peri Pourier is running for South Dakota's District 27 Senate seat on a platform of public safety and improving state and tribal relationships.
First Clade I Mpox case reported in Clark County resident
The Southern Nevada Health District announced Tuesday the first confirmed case of Clade I Mpox in a Clark County resident.
Amazon uses ‘TNF’ to attract new advertisers, expand ad business
'Thursday Night Football' coverage for Amazon has proven a particularly useful tool to expand its advertising and streaming business.
Man arrested after unlawfully entering Alabama School of Math and Science Property, police say
A 44-year-old man was arrested Monday afternoon after unlawfully entering the grounds and a building at the Alabama School of Math and Science, according to the Mobile Police Department.
Buzz of the Week: Do you feel like you have a political home in Utah?
Republican, Democrat, Democratic Socialist, Libertarian, Independent, something else entirely — do you feel like you have a political home in Utah? Let us know what you think.
Jane Muir: Champion of Community and Leader in Business Law
Getting your Trinity Audio player ready... Setting the standard for efficiency and community engagement, while blending professional acumen with altruism Jane Muir is a leader in the Miami legal landscape. She founded J. Muir & Associates in 2018 and has spent over 15 years building a business law practice, a strong team and a sterling […]
Ban ‘intrusive’ cameras on mental health wards in England, say bereaved families
Lawyers tell inquiry ‘patients’ lives are at stake’ through improper use of Oxevision system for most vulnerable
State, local leaders break ground on Bibb County Health Science Academy
The Bibb County Health Science Academy is expected to open in fall 2028.
State, local leaders break ground on Bibb County Health Science Academy
The Bibb County Health Science Academy is expected to open in fall 2028.
Truist Financial Issues Pessimistic Forecast for Accel Entertainment (NYSE:ACEL) Stock Price
Truist Financial lowered their price target on shares of Accel Entertainment from $14.00 to $13.00 and set a "hold" rating on the stock in a research note on Tuesday.
Gimmick or giveback? Even some Trump supporters don't expect to get $5,000 checks after midterms
The offering of government checks has become a go-to tactic for President Donald Trump when he faces a political jam.
Great Lakes Science Center’s Robotics Initiative receives $1 million gift
A $1 million endowment from the Thomas F. Peterson Jr. Charitable Trust will fund robotics education and 3-D printed prosthetics for those in need.
As Summer Crowds Fade, Keystone Businesses Navigate the Annual Shift to Winter
After a summer defined by packed streets, Fourth of July festivities, and celebrations marking America’s 250th anniversary at nearby Mount Rushmore, the tourist hub of Keystone is settling into its quiet off-season
Johnson’s winning coalition fractures as two SEIU locals back Giannoulias
Mayor Brandon Johnson had all three SEIU locals in 2023, but they broke from his coalition after he took office
France could face even worse destruction with second weekend of planned riots, State Dept warns
An internal State Department document warns antifascist protests near Marine Le Pen's National Rally congress in Orléans could spark new unrest.
Hunter Schafer reveals she had gender-affirming bottom surgery: ‘I’m a woman, I’m a girl’
The “Euphoria” star said the experience has been “amazing” and she feels truly herself.
Opinion: A Bears stadium deal must deliver more than a home for football
Keeping the Bears in Chicago could create opportunities for local businesses, but a stadium deal must also deliver measurable economic returns and inclusion.
Moment of Science: New electric current test measures coffee quality without tasting
Getting a clue about the perfect brew! Here's how new research could make sure your morning pick-me-up is "not your average Joe". ☕
Trump takes transactional politics to a new level at latest campaign rally
Trump effectively told Kansans he’s prepared to hurt the state on purpose if he dislikes an election result, which is every bit as remarkable as it sounds.
Trump takes transactional politics to a new level at latest campaign rally
Trump effectively told Kansans he’s prepared to hurt the state on purpose if he dislikes an election result, which is every bit as remarkable as it sounds.
AI scammers target sports fans with celebrity deepfakes
Our investigators reveal how scammers use AI to create convincing fakes of celebrities and athletes, targeting new schemes at fans
AI scammers target sports fans with celebrity deepfakes
Our investigators reveal how scammers use AI to create convincing fakes of celebrities and athletes, targeting new schemes at fans
AI scammers target sports fans with celebrity deepfakes
Our investigators reveal how scammers use AI to create convincing fakes of celebrities and athletes, targeting new schemes at fans
Scientists left in the dark by National Science Foundation grant application delays
The Major Research Instrumentation program offers grants of up to $4 million to scientists buying research equipment
Trump administration announces $8 billion farm relief plan as fuel, fertilizer costs bite
(CNN) — President Donald Trump announced at a Kansas rally on Monday that his administration is introducing an $8 billion aid package for farmers in the face of high diesel
Perspective on CPW’s wolf depredation decision
As state representatives from the Western Slope and Eastern Plains, we are united in standing for our agricultural communities. Colorado Parks and Wildlife’s decision to suspend its chronic wolf-depredation directive breaks faith with voters, with agriculture and with the communities that have borne the true burden of wolf reintroduction. When Proposition 114 narrowly passed in […]
Gravity Media Drives Lifted Entertainment’s <i>I’m A Celebrity… The Wild Frontier</i>, Through Rapid-Deployment IP Production
Gravity Media has rapidly deployed complete IP-based broadcast infrastructure for Lifted Entertainment (part of ITV Studios) on I'm A Celebrity... The Wild Frontier, supporting production in the remote mountain environment...
Paxton campaign showing ‘desperation’ with manufactured story: Political commentator
In the final days until election, President Trump is set to hold another rally in Texas for Republican Senate candidate Ken Paxton. MS NOW National Reporter Rosa Flores shares what she is hearing from voters there. MediasTouch Journalist Adam Mockler, Democratic Strategist Basil Smikle, Bloomberg Businessweek Journalist Max Chafkin, and Rolling Stone Magazine Politics Reporter Nikki McCann Ramirez join the Group Chat with Stephanie Ruhle to share their analysis.
'Unsolved Mysteries' ventures into a new realm: video podcasts
Over the course of nearly four decades, the celebrated show 'Unsolved Mysteries' has evolved amid the changes in the TV business.
These moms regret voting for Trump but aren't sold on Dems
These white suburban mothers were among more than 77 million Americans who voted for Trump in 2024. Now, they say they regret it.
Morning 3: Lincoln County home health worker accused of taking thousands in forged checks -- and other news
Here are the top stories for the morning of Oct. 20, 2026
Nine State Board of Education seats are on the ballot this fall, including 4 in the Greater Houston Area
The state board of education is one of the most influential bodies shaping education across the state. The board sets curriculum and chooses instructional materials for all public school classrooms and in recent years has been scrutinized for its controversial choices.
Wire 3 Begins Construction on Easley Expansion
Wire 3, a leading 100 percent fiber internet provider, announced that construction is underway in Easley, marking another step in the company’s South Carolina expansion. Powered by a fully funded $19 million investment, the Easley expansion will...
MCG and Itiliti Health Form Partnership to Support Health Plans with CMS-0057-F Compliance
/PRNewswire/ -- MCG Health, part of the Hearst Health network and the industry's source of truth for trusted clinical guidance, today announced a strategic...
Mississippi Gulf Coast Community College students use AI to solve business problems
Students at the Harrison County campus are learning ways to solve real-world problems using artificial intelligence.
Trumbull Health Department Holding Walk-in Flu Clinics This Week
The Trumbull Health Department will be having walk-in flu clinics this week:TODAY, 10/20/27: 10-12pm and 2-4pmWednesday, 10/21/26: 6-8pm 335 White Plains Road No appointment required!We will
HOMETOWN HEALTH: Researchers identify new clues for treating type 2 diabetes
The study's authors say this could be developed into new treatments that could help people regulate their blood sugar.
Police trying to identify man in connection with UTV stolen from business
Harrisburg Police are asking for the public’s help in identifying a man in connection with a theft investigation.
Peoria indoor baseball and soccer space celebrates 10 years in business
'It just shows that we can do anything here.'
The problem(s) with the White House’s new women’s health initiative
Under the circumstances, it’s probably best to keep expectations low as the White House’s efforts on this issue get underway.
T-shirts and silver balls: Politics get mixed in with the profane at a Trump store
By Elle Reeve, Samantha Guff, Frank Fenimore, CNN Boones Mill, Virginia (CNN) — Walk into Trump Town USA in Boones Mill, Virginia, and you may marvel at the breadth of human creativity, as long as you’re not distracted by how the merchandise tackles some of the most controversial political issues in the most vulgar way
Seattle Art Museum renovations: Peek inside at construction
An $8.1 million project is underway at Seattle’s flagship art museum, adding more public spaces to gather, work and dine at the museum. Take a peek!
340 Home Care, Home Health, and Hospice Providers Earn Inaugural Trusted & Transparent™ Recognition from Accushield
/PRNewswire/ -- Accushield today announced the inaugural class of Trusted & Transparent™ home-based care companies, with 340 organizations and 883 location...
US Rep. Bynum seeks re-election with Democrats poised for favorable midterm
Candidates are vying for the 5th Congressional District, which the Cook Political Report, a nonpartisan elections forecaster, labels as solidly Democratic.
'Office Space' star Richard Riehle dies at 78
Actor Richard Riehle arrives at the premiere of New Line Cinema's 'A Very Harold & Kumar 3D Christmas' at Grauman's Chinese Theatre on November 2, 2011 in Hollywood, California. (Jason Merritt/Getty Images)Richard Riehle, known for his role in the 1999 film Office Space, has died. He was 78.A statement shared by Artists & Representatives and Wright Entertainment, Inc. announced Riehle's passing on Monday, writing, "Our industry has lost an exceptional talent, and our community has lost a truly wonderful man.""We are deeply saddened to confirm the passing of our beloved client, Richard Riehle, this past weekend," the statement said. "A remarkable actor whose career in theater, film, and television spanned nearly five decades and more than 400 projects, Richard leaves behind an extraordinary legacy."The statement continued, "Beyond his immense talent, he will be remembered for his genuine goodness, boundless kindness, and unwavering generosity, particularly toward emerging actors and filmmakers, whom he encouraged and supported at every opportunity."Born on May 12, 1948, Riehle starred in many television series and films over the years.Notable projects include Casino, The Man from Earth and Deuce Bigalow: Male Gigolo.He got his start as an actor at the University of Notre Dame, where he was involved in the University Theatre and starred in several stage productions. He went on to earn a Master of Fine Arts in acting and directing from the University of Minnesota.While he's played characters that have an "average Joe" presence, he always made the most of his brief screen time.Some roles that he is remembered for include The Quartermaster in Glory, the train guard in The Fugitive, Reverend Scroggins in Fried Green Tomatoes and Bill Cozbi in Bridesmaids.On television, he starred as Principal Ed Rooney in the 1990 series Ferris Bueller and as grandfather Walt Finnerty in the early 2000s sitcom, Grounded For Life.In 2023, he also played Warden Reynolds in Barry.Riehle is survived by his wife, Jane Latham, and their four children.Copyright © 2026, ABC Audio. All rights reserved.
Xbox is struggling for stock so bad that it's encouraging lapsed users to trade-in their dormant consoles ahead of GTA 6
The console stock situation is so dire now that Microsoft is targeting lapsed users with second, dormant Xbox consoles to recommend trading-in. The RAM crisis continues.
Revisiting Brewers' Adames Trade Which Included Rays' Rasmussen
The Milwaukee Brewers transformed their infield with a midseason swap, but the Tampa Bay Rays struck gold by turning a struggling reliever into a dominant ace.
Suspects on motorbikes wanted for business break-ins in Summit County
Akron police are hoping someone recognizes the motorbike riding suspects wanted for recent break-ins.
300+ Charleston builders to gather for heart health talk at Hard Hats with Heart event
Hard Hats with Heart will be hosting their annual networking celebration Tueday. They state that theCharleston construction industry leaders build healthier he
KFF Tracking Poll on Health Information and Trust: Fall 2026 Update on Vaccine Views
The latest KFF Tracking Poll on Health Information and Trust finds about half of parents mistakenly believe spacing out vaccines is healthier for children, while confidence in many long-standing childhood vaccines is high across partisans. These findings take on new relevance following President Trump's recent executive order calling for changes in U.S. childhood vaccine recommendations, including splitting the measles, mumps, and rubella (MMR) vaccine—currently given as a single combined shot—into three separate vaccines across multiple visits.
Hanan Al Kuwari: Executive, Minister, Diplomat - And A Middle-Power Mediator?
The State of Qatar has nominated former minister of public health Dr Hanan Mohamed Al Kuwari for Director-General of the World Health Organization (WHO). Entering a competitive contest alongside six other candidates as the WHO faces financial instability, workforce restructuring, and geopolitical fragmentation, her campaign positions her as a pragmatic, delivery-focused nominee.
Trump continues midterm campaign blitz in North Carolina
President to stump for Michael Whatley, who is facing an uphill battle against Democrat Roy Cooper for the Senate, as elections are just two weeks away
Local men’s health activist running 60 miles to benefit non-profit Movember
The 60 miles represents the 60 men around the world the die by suicide each hour.
Biotech firm Colossal set to return extinct bird’s egg to New Zealand
The biotech firm trying to bring extinct species back to life, Colossal Biosciences Inc., will return an egg from the flightless moa to its native New Zealand.
Trump’s attacks on California elections endanger democracy, repeating a pattern
Republicans questioned elections before reforms made redistricting nonpartisan. Now they accuse California of letting noncitizens vote.
Study links rise in online sports betting to mental health issues
The study’s authors said gambling and sports betting have never been more accessible.
The Broad to move works to Paris and Leimert Park during construction
The Broad will display more than 160 works in a major exhibition at the Fondation Louis Vuitton in Paris during its final phase of construction. It will also partner with Art + Practice in Leimert Park.
Halloween event at The Castle features science behind spooky season
Museum offers hands-on activities with live animals, skeletons and pumpkins.
GM's core profit rises 22% on strength of pickup-truck business
GM shares fell about 6% in premarket trading.
How Much Of Cisco Stock's Rise Did The Business Earn?
Cisco Systems (CSCO) supplies businesses and the hyperscalers building AI infrastructure with networking and security products, along with services. The company's stock climbed 92% between late July 2021 and mid-October 2026, before dividends. A rally of that magnitude makes it natural to credit a growing business. So take a guess: how much of that rise came from Cisco selling more.
United CEO Scott Kirby calls for wealth tax and a near-100% inheritance tax
United Airlines CEO Scott Kirby says wealth inequality threatens society and calls for a national wealth tax and steep inheritance taxes.
2026 Business & Economic Outlook to Explore Key Trends
The Northwest Indiana Business RoundTable ( NWIBRT ) and the Construction Advancement Foundation ( CAF ) will host the 2026 Business & Economic Outlook on Oct. 30, bringing business leaders, …
A note to readers: Science, accountability and elections
Dear readers, As early voting begins, I wanted to share some news — and why it connects to the decisions we make at the ballot box. I’ve been selected for the inaugural cohort of the South Atlantic Climate Journalism Hub mentorship program, hosted by Covering Climate Now. I’m excited to join this group, learn from scientists and fellow journalists, and expand my science reporting. Science directly ties to governance. Local officials make decisions about where development goes, how infrastructure is maintained, what emergency preparations receive funding, and how communities rebuild after disasters. Understanding the evidence behind those decisions helps us evaluate whether our government is serving us well. Here in western North Carolina, those connections are all around us, in Lake Lure and beyond. Flood maps inform decisions about property and development. Engineering assessments help identify risks at dams and bridges. Rainfall forecasts guide emergency preparations. Geological information helps explain landslide hazards. Water testing gives communities information they need to assess conditions. Meteorologists’ knowledge and public perception of weather events shape public safety. Each involves scientific or technical knowledge. Each also raises questions about public responsibility: What did officials know? How did they use that information? What did they tell the public? What did taxpayers receive for their money? A study can identify a problem. Elected officials still have to decide what to do about it, how to pay for it, and how to explain their choices. Reporting should examine both the evidence and the response. That is where I want to strengthen my work. My reporting on Helene recovery, infrastructure, flooding, public safety, and public spending has repeatedly brought me to questions that require scientific expertise alongside public records. This mentorship may help me better understand the research, ask more precise questions, and explain the answers clearly. I also bring the perspective of someone living with these concerns. I live downstream of Lake Lure Dam, and landslides affected my property during Helene. Those experiences bring urgency to my questions. Careful reporting helps establish the answers. Readers deserve to know what the evidence shows, where uncertainty remains, and whether officials accurately describe the information guiding their decisions. You also deserve scrutiny of proposed solutions: what they cost, what they are expected to accomplish, and what risks remain. Access to that information matters. As a mostly deaf journalist who relies on written communication, I will continue pressing for written public warnings, records, and explanations that people can read and use in real time. As you consider the candidates seeking your vote, consider how they approach evidence, preparedness, and transparency. Do they support local journalism, even when it’s not parroting a press release? Do they explain weather events clearly in plain English and explain their decisions after them? Make supporting records available? Acknowledge uncertainty? Follow through when a report identifies a risk? Those are practical questions about governing. Thank you for supporting Cops & Congress and the work that makes these questions part of the public conversation. I’m grateful to David Dickson and the CC Now team for this opportunity, and I look forward to bringing what I learn back to you. Annie DanceEditor & Publisher, Cops & Congress — Learn more about this newsletter, ethics policy, how you can help shape this work, and support it. Follow on X and Facebook. Send constructive criticism, fan mail, and tips with public documents for future stories: CopsandCongress@gmail.com ICYMI: View the Cops & Congress archive — Annie Dance is the publisher of Cops & Congress, a newsletter that analyzes what happens when crime, courts, disaster, democracy, and small-town policies collide. Views expressed here are covered by the First Amendment. Dance has a Bachelor of Arts from Manhattan University in Communication with a focus in Journalism and Government. She has been a journalist for over 20 years. Share Upgrade now or give a gift subscription
Mahjong studio opens in Blue Springs as the centuries-old Chinese game sees a surge in new players
A new Blue Springs studio, Bam Bird Social, is dedicated to teaching and playing mahjong as the game surges in popularity.
GM’s core profit rises 22% on strength of pickup-truck business
By Kalea Hall Oct 20 (Reuters) - General Motors’ third-quarter results easily beat analyst expectations on the back of resolute shoppers who continue to spring for pricey pickups and SUVs. The company on Tuesday said quarterly earnings before interes...
GM's core profit rises 22% on strength of pickup-truck business
General Motors' third-quarter results easily beat analyst expectations on the back of resolute shoppers who continue to spring for pricey pickups and SUVs.
LACMA, Perrotin, the new Metro and now the Brick: Todd Gray is having a banner year
Todd Gray has a solo show opening at the Brick on Oct. 18 — the cap on a banner year including a LACMA commission, a solo show at Perrotin and a public art piece for the Wilshire/La Cienega station for the D line.
As Hollywood implodes, is success still possible for a striving actor?
Last year 34-year-old actor Katie Folger moved from Austin into a Silver Lake casita to pursue her acting dream. Now she's performing a one-woman show called "Getting in Bed With the Pizza Man" at Elysian Theater. But will the TV pilot sell?
Envelope Insiders Live: See stars of 'Furious,' 'Love Story' and more
The creatives behind 'Furious,' 'Love Story,' 'The Only Living Pickpocket in New York' and 'Tenzing' joined us for a day of food, wine and great conversations. Take a look inside.
3 reasons why healthcare organizations ditch tech vendors
Health plans and providers are increasingly inking performance-based contracts with digital health companies to ensure returns on their investment.
How one health system is battling rising uncompensated care costs
Sanford Health is expanding patient navigation and Medicaid renewal support as uncompensated care costs rise and more patients lose coverage.
Would Trump accept GOP midterm losses? 7 in 10 Americans doubt it.
A Post-ABC News-Ipsos poll finds broad confidence that votes will be counted accurately, but deep doubt that the president would accept the results if Republicans lost.
The Data Dive: Steve Kornacki on how Susan Collins could transcend Trump in Maine
Seeking re-election in a blue state, the longtime Republican senator is relying on her personal brand to defy political gravity — again.
Owner of CT information technology consulting business sentenced for computer intrusion scheme
Federal officials said he remotely disabled a client’s computer network on 21 separate days in 2024, which resulted in the company being unable to conduct business on those days.
Water shortages will threaten growth within five years, say over half of European industrial leaders
Water stress is already hitting operating costs, supply chains and infrastructure across European industryWater shortages now rank as high as cybe...
Xbox 'Business Strategist' Claims Video Game Industry Is 'Pretending to Not Use AI,' Deletes Twitter Account After Deluge of Replies
An Xbox staff member went viral this week for taking to social media to tell "the truth that nobody wants you to know": that the video game industry is "pretending" to not use AI.
Office conversions boost downtown Grand Rapids’ commercial real estate market
Downtown Grand Rapids office conversions are creating scarcity in the market, and will add more residents downtown.
Republicans in competitive Pa. races are tying themselves to Josh Shapiro. What does that mean for the midterms?
Republicans in competitive swing district races are featuring Gov. Josh Shapiro in ads. It's "quite telling," one political science professor said.
Data Centers Play Delicate Game to Weather Political Backlash
Demand for the data centers powering artificial intelligence is booming even as developers find themselves playing political defense.
A key climate report was scrapped under Trump. Scientists plowed ahead with the research.
Some of the ousted climate scientists have just published their own research paper, identifying changes in the research field.
Threats of political violence soar in Australia’s ‘online echo chamber’
Independent lawmaker Helen Haines was in critical condition after being struck deliberately by a car.
New health science center to be featured at Altrusa Oak Ridge meeting
Altrusa International will host a program on the new 130,000 square foot Roane State health science center.
New health science center to be featured at Altrusa Oak Ridge meeting
Altrusa International will host a program on the new 130,000 square foot Roane State health science center.
Banijay Confirms Senior Leadership Structure
The newly-minted Banijay Entertainment has set out its senior leadership team following the merger with All3Media.
Pfizer makes ‘business decision’ to end phase 2 trial of autoimmune drug as program’s future uncertain
Pfizer has called time on a phase 2 trial of its CXCR5 antibody in an autoimmune blood disorder, with the company tight-lipped on whether this marks the end of the road for the asset. The Big Pharma had been evaluating the therapy, dubbed PF-06835375, in a phase 2 study of 61 patients with primary immune thrombocytopenia (ITP) that kicked off in 2022, according to the federal trials register. However, Pfizer confirmed to Fierce on Monday that this study had been terminated “due to a business decision.” “The decision to terminate the trial was not based on any safety concerns,” a spokesperson pointed out. At time of publication, PF-06835375 remained listed on Pfizer’s website for both ITP and lupus. A phase 1 study in lupus wrapped up in 2022, according to the trials database. ITP is an autoimmune disorder characterized by a low platelet count. Novartis was at one point evaluating its B-cell-depleting antibody ianalumab—recently approved as Fabhalta to treat immunoglobulin A nephropathy—as a potential treatment ITP. But the therapy struggled to demonstrate a benefit in the clinic for this indication. When contacted by Fierce, Pfizer wouldn’t confirm whether all work on PF-06835375 has been halted, and whether the company has any other plans to explore C-X-C chemokine receptor type 5 (CXCR5) as a mechanism. CXCR5 is found in blood cancers such as diffuse large B-cell lymphoma and mantle cell lymphoma chemokine receptor. However, there is little expression in normal tissue, which has led some drug developers to explore its potential. Vincerx Pharma had at one point been planning to take an anti-CXCR5 ADC into the clinic to treat B-cell malignancies, but that ambition was scrapped due to cash constraints. Where Big Pharma is placing its bets is one of the hot topics being discussed at Fierce Biotech's high-impact event in London next month. Find out more information and register by clicking on the banner below: [ ](https://qtxasset.com/quartz/qcloud5/media/image/where_big_pharma_is_placing_its_bets.png?VersionId=B8JrRbJ.pFUSK1pJgjeWHLGm_18RdLAy)
Roland n/vision Review: Vision for the Future or Late to the Party?
The new Roland n/vision is the company’s first true wavetable synth. Can the latest addition to the Boutique series hold its own against the competition?
Trump’s Approval Rating Plunges to Historic Low Ahead of Midterm Elections
68% of Americans disapprove of Trump's handling of the economy, including 37% of respondents who identify as Republicans.
James Maddison marks first Tottenham start in nearly 18 months with stunning goal in first Premier League win of season
Tottenham playmaker struck opener in 3-1 win over Coventry which moved side off foot of Premier League; the 29-year-old was making his first start following torrid long lay-off after suffering an ACL injury
Nvidia CEO urges German manufacturers to adopt AI
FRANKFURT, Germany — Nvidia CEO Jensen Huang urged Germany’s makers of cars and industrial machines to quickly adopt artificial intelligence to “re-engineer” the country’s struggling business model by tapping its