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Former Dolphins RB Raheem Mostert blasts Mike McDaniel's coaching style: 'I need someone tough'
McDaniel's style clearly isn't for everyone
Scientists find the genetic switch that makes pancreatic cancer resist chemotherapy
Scientists have identified a crucial molecular switch that decides whether pancreatic cancer cells resist chemotherapy or respond to it. The key player, a gene called GATA6, keeps tumours in a more structured and treatable form—but it gets shut down by an overactive KRAS-driven pathway. When researchers blocked that pathway, GATA6 levels rebounded and cancer cells became more sensitive to chemo. The discovery could help turn some of the toughest pancreatic tumours into ones doctors can better control.
Vulnerable Republicans in California's redrawn congressional districts back war in Iran
Republicans facing tough reelection fights in this year's midterms are backing President Trump's attacks on Iran, which are unpopular, according to recent polling.
Galaxy S26 vs. S26+ vs. S26 Ultra: Everything You Need to Know About Samsung's 2026 Flagship Phones
Samsung's Galaxy S26 lineup has arrived, and on the surface, all three models look equally compelling—making your buying decision tougher than ever. I break down what sets each phone apart to help you decide which one best fits your needs.
States Move to Limit Access to H.I.V. Treatment
Citing shortfalls in federal support, about 20 states are toughening eligibility requirements for patients in drug assistance programs.
Miami Dolphins make decision on Tua Tagovailoa
The NFL Scouting Combine has come to a close, and teams now move towards the new league year. Some teams have tough decisions to make with limited time to do so. The Miami Dolphins, however, appear to have made their…
For the first time, light mimics a Nobel Prize quantum effect
Scientists have pulled off a feat long considered out of reach: getting light to mimic the famous quantum Hall effect. In their experiment, photons drift sideways in perfectly defined, quantized steps—just like electrons do in powerful magnetic fields. Because these steps depend only on nature’s fundamental constants, they could become a new gold standard for ultra-precise measurements. The discovery also hints at tougher, more reliable quantum photonic technologies.
Business of Farming Conference aims to support local farmers
The year 2025 was tough for farms in the region recovering from Helene damage.The Appalachian Sustainable Agriculture Project (ASAP) held its annual Business of
A Grip on Sports: The best way to remember a lost loved one may be the most personal question someone can answer, even when it plays out in public
A GRIP ON SPORTS • Friday was a tough day. For a lot of reasons. Some parts of life, and death, are harder to deal with than others.
Political Candidates and the Troubling Chill Factor
Whether it’s political polarization, ruthless social media or federal interference, this is a particularly tough time to be in elected office in a city or a state.
Youth sports in CT create stress, inequality and distrust
Youth sports are not just becoming more expensive, they are more stressful, unequal, and tougher on kids' mental health.
Trump heads weakened into a season of tough political challenges
President Trump is in a precarious position with the 2026 midterm elections just ahead, but he and his supporters express confidence.
The Beginner's Blueprint For Building AI Agents That Handle Your Toughest Business Tasks
This practical guide explains how to design agentic workflows using a simple inputs, tasks and outputs framework, so any business leader can move from idea to execution.
Trump issues patriotic rallying cry as he faces tough political headwinds
The BBC's Anthony Zurcher was in the chamber as the US president delivered a lengthy sales pitch to the nation.
Houston’s Kelvin Sampson reacts to getting humbled by tough schedule
Houston coach Kelvin Sampson gave proper credit to Kansas after their much-anticipated matchup at Allen Fieldhouse on Monday.
Dating has been hard as an American living in another country
Dating and finding love abroad has been hard as an American living in Paris. The language barrier and cultural differences are tough to navigate.
Matchday 1: New York City vs LA Galaxy at Dignity Health Sports Park
New York City FC begin their 2026 season with a Justin Haak reunion and a tough test in primetime against a retooled LA Galaxy.
Michigan basketball players react to Duke's 'really tough' defense
Michigan basketball players Yaxel Lendeborg and Morez Johnson Jr. react to Duke's elite defense, calling it the best they've faced.
Lawmakers consider property tax cap as mayors, business owners clash over impact
Some business owners say rising tax rates are forcing them to make tough decisions about staying open.
The Boston accent melts her heart
How are ya? A tough winter has brightened with the voices on the Globe’s Boston Accent Hotline.
Trumbull County business owners express importance of shopping small
It seems to be happening a lot lately: small businesses here locally making the tough decision to close their doors.
Trumbull County business owners express importance of shopping small
It seems to be happening a lot lately: small businesses here locally making the tough decision to close their doors.
Illinois Democrat tries to bleep her way through a tough Senate primary with a new expletive-laden anti-Trump ad
Senate candidate Juliana Stratton's new ad full of f-bombs is the latest move in a contest that has centered on the president.
Rep. Tony Gonzales had affair with aide who lit herself on fire, lawyer alleges
The congressman from Texas, who is facing a tough primary battle, has denied having an affair.
Fernando Mendoza admits he nearly picked Georgia over Indiana
It was a tough decision for the Heisman winner, who nearly signed with Georgia out of the transfer portal
Eagles Stay or Go 2026: Special teams
Reuben Frank and Dave Zangaro bring back Stay or Go in 2026, trying to figure out the futures of every Eagles player on the roster. We already took a look, at quarterback, running back, receiver, tight end, interior offensive line, offensive tackle, edge rusher, defensive tackle, linebacker, cornerback and safety. Up last: Specialists. Jake Elliott Roob: Tough one because Elliott has been so…
Gov. Tim Walz faces tough political reality as he seeks to assert himself in final year in office
Republicans in the tied Minnesota House are already signaling opposition to the governor’s policy agenda, setting up early clashes as lawmakers returned to St. Paul this week.
Mapped: How much Minnesotans spend on health care
The findings show how tough it can be to afford health care, even with insurance.
Making Sense of Politics in a Messy Sports World
Whether, and how, to talk about tough issues.
GCU students put their passion into politics at statehouse
It can be tough working in government and politics with the polarization and rancor around it these days. But Kady Binsbacher sees it as a […]
Messes around every corner: A year under new ownership, former Steward hospitals continued to bleed
The acquiring health care systems knew they faced a tough situation, but few expected the takeovers to be this hard.
South Florida leaders push crackdown on Cuba-linked firms, a lifeline for thousands of families
Miami-Dade and local leaders seek tougher action on Cuba trade, revoking licenses, urging federal probes and targeting flights, remittances and shipments.
From Detroit to Charlotte: How a business coach built a culture of ‘tough love’
Nikita Allen trains Black entrepreneurs and others to build sustainable businesses in the Charlotte region.
Today’s Papers: An historic Juve blunder, Galagoal, Bastoni apology
La Gazzetta dello SportNot like that An historic gaffe in the Champions LeagueBremer ko, Cabal sent off, Galatasaray win 5-2. It will be very tough to qualify for the round of 16 in Turin on the 25th...
Oscar-winning actor Robert Duvall dead at 95
Robert Duvall, the Oscar-winning actor best known for “The Godfather,“ Apocalypse Now” and many other tough-guy roles over an acclaimed screen career that spanned six decades, has died. He was 95.
Oscar-winning actor Robert Duvall dead at 95
(CNN) — Robert Duvall, the Oscar-winning actor best known for “The Godfather,“ “Apocalypse Now” and many other tough-guy roles over an acclaimed screen career that spanned six decades, has died.
Dolphins start a tough rebuild by cutting Tyreek Hill and Bradley Chubb, and likely Tua Tagovailoa too
Al Roker Offers Words of Encouragement After a Tough Week in Calming Instagram Videos
“It’s going to be another week, and we just have to get in there and get it done,” Al said.
Microplastics have reached Antarctica’s only native insect
Even Antarctica’s toughest native insect can’t escape the reach of plastic pollution. Scientists have discovered that Belgica antarctica — a tiny, rice-sized midge and the southernmost insect on Earth — is already ingesting microplastics in the wild. While lab tests showed the hardy larvae can survive short-term exposure without obvious harm, those exposed to higher plastic levels had reduced fat reserves, hinting at hidden energy costs.
This SF sports legend has a Hollywood-worthy spy story
While parts of her biography are tough to pin down, Marble's impact was undeniable.
‘Hard things are what’s cool about sport’: Anchorage’s Gus Schumacher on a tough Olympics start
After a strong run of World Cup finishes this season, Schumacher reflects on some of the disappointment of his Olympic experience and how he hopes to progress.
Winter Olympics 2026: Jordan Stolz conquers his toughest speed skating test, wins gold in 500 to stay on historic pace
Winter Olympics 2026: Jordan Stolz conquers his toughest test, wins gold in 500 to stay on historic pace
Record-breaking gravitational wave puts Einstein's relativity to its toughest test yet — and proves him right again
A record-breaking gravitational wave signal let scientists "listen" to a distant black hole merger and put Einstein's gravity to its toughest test yet.
Takeaways: Enforcement surge ending in Minneapolis as state and DHS officials face tough questions in Senate
While White House border czar Tom Homan announced Thursday morning the federal immigration surge in Minnesota would be ending, state officials were facing tough questions about the circumstances that led to that crackdown in the first place.
How business students learn to make ethical decisions by studying a soup kitchen in one of America’s toughest neighborhoods
For 50 years, St. Francis Inn in Philadelphia has served the poorest and most vulnerable people in Kensington.
How business students learn to make ethical decisions by studying a soup kitchen in one of America’s toughest neighborhoods
For 50 years, St. Francis Inn in Philadelphia has served the poorest and most vulnerable people in Kensington.
Three Healthcare VCs That Are Beating a Tough Fundraising Market
Venture capitalists focused on health are struggling to entice skeptical investors—but a handful are succeeding.
Netanyahu to push Trump to take tough Iran stance during White House visit
Israeli PM is expected to press the president to take a harder line over Iran’s nuclear program
Charted: Where health coverage breaks the bank
The findings show how tough it can be to afford health care, even with insurance.
Takeaways from a tense House hearing with Trump immigration officials
With the Trump administration’s mass deportation push under intense scrutiny, the heads of Immigration and Customs Enforcement, Customs and Border Protection, and US Citizenship and Immigration Services faced tough questions during a congressional committee hearing on Tuesday.
Super Bowl ads try to overcome tough times with health, caring and the usual laughs
At a difficult time for America, Super Bowl advertisers ask viewers to take care of themselves and others — and maybe even crack a smile.
Super Bowl ads try to overcome tough times with health, caring and the usual laughs
There is plenty of silliness in this year’s commercials.
Super Bowl ads try to overcome tough times with health, caring and the usual laughs
At a difficult time for America, Super Bowl advertisers are asking viewers to take care of themselves and others — and maybe even crack a smile.
Super Bowl Ads Try to Overcome Tough Times With Health, Caring and the Usual Laughs
At a difficult time for America, Super Bowl advertisers ask viewers to take care of themselves and others — and maybe even crack a smile. Ring shows how neighbors can use their doorbell cameras to find lost pets. A Budweiser Clydesdale protects a bald eagle chick from the rain. Novartis touts a ...
This tiny molecular trick makes spider silk almost unbreakable
Scientists have cracked a key mystery behind spider silk’s legendary strength and flexibility. They discovered that tiny molecular interactions act like natural glue, holding silk proteins together as they transform from liquid into incredibly tough fibers. This same process helps create silk that’s stronger than steel by weight and tougher than Kevlar.
Trump says Minneapolis showed him 'softer touch' needed on immigration
“I learned that maybe we could use a little bit of a softer touch. But you still have to be tough,” Trump told NBC News.
After the Minneapolis shootings, Trump says his administration could use 'a softer touch' on immigration
In an exclusive interview with NBC News, President Donald Trump added: "But you still have to be tough."
All eyes on Johnson as House returns amid partial government shutdown
The speaker faces tough days ahead trying to pass a federal funding package and prevent a prolonged partial government shutdown
Sports Daily: KU salvages otherwise tough weekend for college basketball in Kansas
KU beats BYU, Wichita State and K-State fall in action this weekend.
Speaker Johnson must sell conservatives on funding deal Democrats pushed for — or risk lengthy government shutdown
House Speaker Mike Johnson is back in Washington this week with a tough ask for his fellow Republicans: accept a funding deal that Democrats pushed for or risk another painful, prolonged government shutdown.
When Health Insurance Costs More Than the Mortgage
As health care costs skyrocket and federal lawmakers pull back help on insurance premiums, more middle-income families are facing tough choices on health care.
Texas Republicans shift messaging around ICE tactics amid election-year risks
With midterm elections approaching, Texas Republicans are publicly questioning ICE's tactics following deadly and controversial enforcement actions. Analysts say the rhetoric reflects growing political vulnerability rather than a true break from the party's tough stance on immigration.
New businesses struggle in Missouri. An immigrant-owned bakery is beating the odds
Nearly half of all new businesses in the U.S. shut down within five years, and Missouri businesses face even tougher odds. Despite the obstacles, one immigrant-owned bakery is bringing something new to Missouri.
Youssef (26 points) leads Pinkerton boys past Londonderry
LONDONDERRY -- In typical fashion, Friday night’s rivalry game between the Pinkerton Academy and Londonderry boys basketball teams began with a tough and gritty feel to it.
Plain Talk: 'Our business climate in North Dakota is eroded'
On this Plain Talk, Ron Ness, president of the North Dakota Petroleum Council, talks about the tough economic environment for the state's oil and gas developers.
Why the UK’s toughest immigration voices are often politicians of colour
As parties harden their stance on borders, minority politicians have become political cover against racism accusations.
Yankees news: The ZiPS Projections are in
FanGraphs’ ZiPS projections show AL East will be tough once again; is the window running out; a minor move
A Soulslike where survival is everything and a mountain is the boss
Climbing is combat in the tough, mesmerizing mountaineering game Cairn
Minneapolis small business supports strike against ICE, raises money
ICE activity and tariffs are making for an especially tough month for Perennial Cycle in Minneapolis. The owner is focusing on the community.
Analysis: Why the Minnesota deportation impasse will be so hard to solve
What happens now that the tough Minnesota deportation crackdown has turned tragic depends on whether President Donald Trump concludes he simply has an optics problem or whether he’s ready to make genuine changes to unpopular hardline policies that are central to his political identity.
Ranking 2026 Big Ten football schedules from easiest to toughest
Big Ten heavyweights must overcome grueling schedules in 2026 to reach their ultimate destination
Illinois faces its toughest challenge yet in No. 2 UCLA
Wallace, Parchment, and the Illini look to make a splash in conference play
Kawhi Leonard, Clippers ready to feast on porous Jazz defense
It's tough to find an NBA team currently playing better basketball than the Los Angeles Clippers.
Pistons launch tough road trip with test vs. Nuggets
The slog of an 82-game schedule becomes tough in January, when winter has settled in and injuries add up.
Tennessee's tough task: Slow down high-octane Georgia
Tennessee, which boasts the No. 1-ranked defense in the Southeastern Conference, will try to slow down the league's top offensive team when it visits Georgia on Wednesday in Athens, Ga.
Rebuffed Burnham can return to honing his stature and attack lines
Greater Manchester mayor will not be tested in tough byelection or against PM for now, but can continue to pose speculative threat
Three Takeaways From Northwestern’s 71-64 Loss to UCLA
More of the same in a tough loss in Los Angeles.
Toughest Places To Play In North America: Where Do Arrowhead, Michigan Stadium Rank?
Here are the toughest places to play in sports across North America.
Blackhawks face another tough foe in reigning champion Panthers
The Chicago Blackhawks are still working their way out of a rebuild. But after going toe-to-toe with two of the NHL's best, they'll look to keep it going when they host the back-to-back Stanley Cup champion Florida Panthers on Sunday.
Open Thread: 25 January 2026
The Daily Merengue is a place where you can feel free to d all things football. Do not be alarmed by the overt RMCF bias. It’s in the name! Shoutout to the mods who do a fantastic job, Ezek, Valyrian Steel, Kung_Fu_Zizou, Juninho, NeRObutBlanco and yours truly, Felipejack. Victory! Villarreal is usually a tough opponent. We won and kept a clean […]
Buffs drop fifth-straight conference game to UCF
The last few games have been a tough stretch for Tad Boyle and the Colorado Buffaloes, falling to all four of their previous opponents. It didn’t get any better on Saturday afternoon, as the Buffs fell to the UCF Knights in Boulder by a final score of 95-86. CU entered the game as 3.5-point favorites […]
McGeeney expects 'tough one' for Armagh in Monaghan
Armagh football manager Kieran McGeeney expects Sunday's Division One opener away to Monaghan [14:00 GMT, live on BBC iPlayer and BBC Sport NI website] to be a "tough one".
Arizona State hosts Cincinnati as both clubs seek better results
While the Big 12 proves to be one of the toughest conferences in college basketball, it's still an entertaining slugfest for teams that find themselves at the bottom of the conference standings.
Pacers upset Thunder in NBA Finals rematch, easily the highlight of a tough season for Indiana
Cuthbert on 'tough love' and WSL title race
Chelsea's Erin Cuthbert and Alyssa Thompson discuss the WSL title race, learning "tough love" and adapting to a new club.
Top 25 And 1: No. 2 Nebraska moves to 19-0 after third straight double-digit win
The Cornhuskers have their toughest test ahead, however, as a date with Michigan awaits on Tuesday
Samsung Galaxy S26 Ultra might finally kill screen protectors
Tougher new Gorilla Glass incoming
Tougher stance on Trump is 'very good for business', says JP Morgan's Europe boss as CEOs welcome tariff U-turn
Market watches breathed sigh of relief on President Donald Trump's tariff U-turn, but keep focused on corporate resilience.
Farmers Now Owe a Lot More for Health Insurance
More than a quarter of the agricultural workforce purchases health insurance through the individual marketplace, a much larger share than the overall percentage of U.S. adults. After a tough year for farmers, the loss of enhanced ACA subsidies is putting health insurance out of reach for many.
Congress’ health deal still has hurdles
The package, which would put guardrails on to drug intermediaries, faces a tough test this week.
PCA soaking up Chicago sports scene: 'It's on another level'
CHICAGO -- The video clip quickly made its way across social media platforms on Monday night. Bears quarterback Caleb Williams -- one night after a tough loss to the Rams in the NFL playoffs -- was sitting in the front row at the United Center for a Blackhawks game. As
Miami, Indiana turn championship into one of toughest tickets in memory
According to Ticketdata, the lowest "get-in" price at Hard Rock Stadium, not far from the Miami campus, was $3,652 about 24 hours before kickoff
Even MBAs From Top Business Schools Are Struggling to Get Hired
Finding a professional job right now is so tough that it’s taking many of America’s most credentialed business-school graduates months to land offers.
Burnley analysis: Jubilant Clarets earn hard-fought point
As Anfield emptied out, the Burnley players and their travelling supporters celebrated jubilantly. West Ham's win at Spurs was bad news for the Clarets' slim survival hopes, but this result was a rare moment of joy in an otherwise tough season for Scott Parker's side. On another day, Burnley could have been three or four goals down by the time they scored, but they showed courage and took advantage of Liverpool's sloppiness.
Lakers get tough news on Luka Doncic before Blazers game
This is more rough news for the Lakers.
What Voters Told Democrats About ICE, Rising Costs and Party Perceptions
In focus groups, swing voters gave Democratic politicians some tough feedback on the party.
Chuck Schumer Calls His Shot
After securing strong recruits on a tough Senate map, the Democratic leader is not only predicting an upset 2026 victory, but also naming the states he thinks his party can flip.
BP Flags $5 Billion Write-Down in Low-Carbon Segment, Warns of Weak Oil Trading
The warning and impairment—in its gas and low-carbon energy segment—cap off a tough year for the industry.